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README.md
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---
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task_categories:
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- question-answering
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tags:
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- biology
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- medical
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size_categories:
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- n<1K
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---
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# Target-QA: QA Dataset Based on DepMap Multi-Omics Profiles and CRISPR Outcomes
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## Dataset Summary
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---
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## Supported Tasks and Benchmarks
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- **Graph-Augmented Question Answering**
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---
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## Preprocessing Details
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- **Starting cohort**: 985 DepMap cell lines
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- 649 annotated (cancerous)
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- 336 non-annotated or non-cancerous
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- **Target-QA subset**: 363 overlapping with CRISPR gene effect data
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- **Omics modalities integrated into 834,809 entities**:
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- Promoter: 86,238
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- Gene: 86,238
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- Transcript: 412,039
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- Protein: 121,419
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- **Knowledge graph integration**:
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- Protein–protein interactions: 17,151,453 edges
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- Disease–target associations: 27,087,971 edges
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> **Note:** Methylation values excluded due to high saturation.
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---
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## Data Splits
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- **Pretraining set**: 336 samples
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- Train: 269
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- Test: 67
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- **Target-QA set**: 363 samples
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- Train: 300
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- Test: 63
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**Test distribution includes:** LUAD (7), BRCA (6), COAD/READ (5), PAAD (4), GBM (3), SARC (3), OV (3), SKCM (3), ESCA (3), SCLC (3), HNSC (2), LUSC (2), STAD (2), etc.
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---
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## Prompt Design
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### Initial Prompt (`P_init_n`)
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# Target-QA: QA Dataset Based on DepMap Multi-Omics Profiles and CRISPR Outcomes
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## Dataset Summary
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---
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## Preprocessing Details
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+

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- **Starting cohort**: 985 DepMap cell lines
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- 649 annotated (cancerous)
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- 336 non-annotated or non-cancerous
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- **Target-QA subset**: 363 overlapping with CRISPR gene effect data
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- **Omics modalities integrated into 834,809 entities**:
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- Promoter: 86,238
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- Gene: 86,238
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- Transcript: 412,039
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- Protein: 121,419
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- **Knowledge graph integration**:
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- Protein–protein interactions: 17,151,453 edges
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- Disease–target associations: 27,087,971 edges
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> **Note:** Methylation values excluded due to high saturation.
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---
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## Data Splits
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- **Pretraining set**: 336 samples
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- Train: 269
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- Test: 67
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- **Target-QA set**: 363 samples
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- Train: 300
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- Test: 63
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**Test distribution includes:** LUAD (7), BRCA (6), COAD/READ (5), PAAD (4), GBM (3), SARC (3), OV (3), SKCM (3), ESCA (3), SCLC (3), HNSC (2), LUSC (2), STAD (2), etc.
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---
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## Supported Tasks and Benchmarks
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- **Graph-Augmented Question Answering**
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---
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## Prompt Design
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### Initial Prompt (`P_init_n`)
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