Lal Claude Opus 4.6 commited on
Commit
daf5b75
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1 Parent(s): 1e6bbe9

Fix loading instructions and add dataset metadata

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- Fix repo_type="dataset" missing from hf_hub_download (was causing 404)
- Fix variable name collision (ad overwrote import)
- Fix import consistency (import anndata, not as ad)
- Add matrix format info (Sparse CSC, float32)
- Add data splits table (train/valid/test counts)
- Document missing .var columns (width, cre_idx)
- Add cre_class possible values
- Fix title typo (human-catlas-atac -> human-atac-catlas)

Co-Authored-By: Claude Opus 4.6 <noreply@anthropic.com>

Files changed (1) hide show
  1. README.md +20 -9
README.md CHANGED
@@ -10,7 +10,7 @@ size_categories:
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  - 1M<n<10M
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  ---
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- # human-catlas-atac-data
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  ## Dataset Summary
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  This dataset provides a binary accessibility matrix of candidate Cis-Regulatory Elements (cCREs) across human cell types. It is derived from the CATlas project (https://decoder-genetics.wustl.edu/catlasv1/catlas_humanenhancer/#!/). The matrix identifies which genomic regions are accessible (1) or inaccessible (0) across 204 distinct cell types. The data is derived from https://decoder-genetics.wustl.edu/catlasv1/humanenhancer/data/cCRE_by_cell_type/. The hg38 genome build was used.
@@ -24,6 +24,14 @@ This dataset provides a binary accessibility matrix of candidate Cis-Regulatory
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  ### AnnData Object Dimensions
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  - **n_obs (Cell Types):** 204
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  - **n_vars (cCREs):** 1,121,319
 
 
 
 
 
 
 
 
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  ### Data Fields
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  - **`.X`**: A sparse binary matrix where rows are cell types and columns are genomic regions (cCREs).
@@ -31,22 +39,25 @@ This dataset provides a binary accessibility matrix of candidate Cis-Regulatory
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  - `cell type`: The descriptive name of the human cell type/cluster.
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  - **`.var` (Genomic Feature Metadata):**
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  - `chrom`, `start`, `end`: Genomic coordinates (hg38).
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- - `cre_class`: Classification of the regulatory element.
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- - `in_fetal` / `in_adult`: indicators of activity in developmental stages.
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  - `cre_module`: Associated regulatory module.
 
 
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  - `enformer_split`: Overlap with the data splits used for training the Enformer model.
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- - `split`: Splits used for downstream modeling (training/validation/test).
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  ## Usage
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  ```python
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- import anndata as ad
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  from huggingface_hub import hf_hub_download
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  file_path = hf_hub_download(
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- repo_id="Genentech/human-atac-catlas-data",
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- filename="data.h5ad"
 
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  )
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- ad = anndata.read_h5ad(file_path)
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- ```
 
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  - 1M<n<10M
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  ---
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+ # human-atac-catlas-data
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  ## Dataset Summary
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  This dataset provides a binary accessibility matrix of candidate Cis-Regulatory Elements (cCREs) across human cell types. It is derived from the CATlas project (https://decoder-genetics.wustl.edu/catlasv1/catlas_humanenhancer/#!/). The matrix identifies which genomic regions are accessible (1) or inaccessible (0) across 204 distinct cell types. The data is derived from https://decoder-genetics.wustl.edu/catlasv1/humanenhancer/data/cCRE_by_cell_type/. The hg38 genome build was used.
 
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  ### AnnData Object Dimensions
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  - **n_obs (Cell Types):** 204
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  - **n_vars (cCREs):** 1,121,319
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+ - **Matrix format:** Sparse CSC (scipy.sparse.csc_matrix), float32
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+
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+ ### Data Splits
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+ | Split | Count |
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+ |-------|-------|
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+ | train | 977,014 |
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+ | valid | 71,798 |
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+ | test | 72,507 |
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  ### Data Fields
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  - **`.X`**: A sparse binary matrix where rows are cell types and columns are genomic regions (cCREs).
 
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  - `cell type`: The descriptive name of the human cell type/cluster.
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  - **`.var` (Genomic Feature Metadata):**
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  - `chrom`, `start`, `end`: Genomic coordinates (hg38).
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+ - `cre_class`: Classification of the regulatory element (Promoter, Promoter Proximal, or Distal).
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+ - `in_fetal` / `in_adult`: Indicators of activity in developmental stages.
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  - `cre_module`: Associated regulatory module.
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+ - `width`: Width of the cCRE region in base pairs.
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+ - `cre_idx`: Index of the cCRE.
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  - `enformer_split`: Overlap with the data splits used for training the Enformer model.
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+ - `split`: Splits used for downstream modeling (train/valid/test).
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  ## Usage
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  ```python
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+ import anndata
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  from huggingface_hub import hf_hub_download
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  file_path = hf_hub_download(
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+ repo_id="Genentech/human-atac-catlas-data",
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+ filename="data.h5ad",
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+ repo_type="dataset"
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  )
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+ adata = anndata.read_h5ad(file_path)
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+ ```