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# Prokaryotic Genome CDS Annotation Summary
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## Abouts
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In this repository, we present the evaluation datasets for prokaryotic genome annotation tasked. Through comprehensive evaluations, GENERanno-cds-annotator achieves superior accuracy compared to traditional HMM-based methods (e.g., [GLIMMER3](https://ccb.jhu.edu/software/glimmer/index.shtml), [GeneMarkS2](https://genemark.bme.gatech.edu/genemarks2.cgi), [Prodigal](https://github.com/hyattpd/Prodigal?tab=readme-ov-file)) and recent LLM-based approaches (e.g., [GeneLM](https://www.biorxiv.org/content/10.1101/2025.03.20.644312v1)), while demonstrating exceptional generalization ability on archaeal genomes.
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