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Update README.md
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README.md
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### `syn_human` · `syn_mouse` — Synonymous codon substitution (20,000 pairs each)
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Codons within a real CDS are replaced with the highest-frequency synonym for the target
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species
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downstream flanking sequence is left unchanged. Amino acid identity is preserved by
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construction. The model should prefer the natural codon usage over the artificially
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optimised variant.
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patch is identical between original and perturbed.
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- Annotations: GENCODE v45 / GRCh38; 9,705 unique genes.
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- Window layout:
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---
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### `syn_human` · `syn_mouse` — Synonymous codon substitution (20,000 pairs each)
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Codons within a real CDS are replaced with the highest-frequency synonym for the target
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species, while the upstream and
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downstream flanking sequence is left unchanged. Amino acid identity is preserved by
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construction. The model should prefer the natural codon usage over the artificially
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optimised variant.
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patch is identical between original and perturbed.
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- Annotations: GENCODE v45 / GRCh38; 9,705 unique genes.
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- Window layout: 8,102 bp upstream flank, CDS near the right edge.
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