| { | |
| "CO2H-tBu deprotection": [ | |
| 1309, | |
| 228, | |
| 51, | |
| 1518, | |
| 563 | |
| ], | |
| "Triflyloxy Sonogashira coupling": [ | |
| 31, | |
| 28, | |
| 17, | |
| 94, | |
| 13 | |
| ], | |
| "CO2H-Me deprotection": [ | |
| 44348, | |
| 48540, | |
| 35741, | |
| 5697, | |
| 38698 | |
| ], | |
| "Grignard + acid chloride ketone synthesis": [ | |
| 54, | |
| 4, | |
| 3, | |
| 11, | |
| 27 | |
| ], | |
| "Friedel-Crafts acylation": [ | |
| 238, | |
| 517, | |
| 27, | |
| 203, | |
| 429 | |
| ], | |
| "Bromo Grignard reaction": [ | |
| 1805, | |
| 3679, | |
| 4827, | |
| 2278, | |
| 6630 | |
| ], | |
| "Pinner reaction": [ | |
| 26, | |
| 653, | |
| 1731, | |
| 1393, | |
| 1138 | |
| ], | |
| "Sulfanyl to sulfonyl": [ | |
| 39, | |
| 55, | |
| 195, | |
| 86, | |
| 26 | |
| ], | |
| "Ester Schotten-Baumann": [ | |
| 1519, | |
| 6224, | |
| 1584, | |
| 5881, | |
| 5635 | |
| ], | |
| "Weinreb ketone synthesis": [ | |
| 2472, | |
| 1083, | |
| 177, | |
| 1881, | |
| 2196 | |
| ], | |
| "Isocyanate + amine urea coupling": [ | |
| 4090, | |
| 12403, | |
| 2582, | |
| 9606, | |
| 11850 | |
| ], | |
| "Sulfonamide Schotten-Baumann": [ | |
| 12601, | |
| 4558, | |
| 3003, | |
| 14935, | |
| 18965 | |
| ], | |
| "Mitsunobu sulfonamide reaction": [ | |
| 81, | |
| 238, | |
| 103, | |
| 389, | |
| 284 | |
| ], | |
| "Iodo N-alkylation": [ | |
| 7428, | |
| 5977, | |
| 2664, | |
| 6065, | |
| 5820 | |
| ], | |
| "Hydroxy to chloro": [ | |
| 858, | |
| 2745, | |
| 1093, | |
| 2874, | |
| 2799 | |
| ], | |
| "Ketone Dess-Martin oxidation": [ | |
| 2654, | |
| 292, | |
| 2495, | |
| 2600, | |
| 700 | |
| ], | |
| "Iodo Miyaura boration": [ | |
| 273, | |
| 373, | |
| 125, | |
| 83, | |
| 236 | |
| ], | |
| "SNAr ether synthesis": [ | |
| 24867, | |
| 17691, | |
| 41943, | |
| 36500, | |
| 14392 | |
| ], | |
| "Bromination": [ | |
| 11216, | |
| 5313, | |
| 13809, | |
| 12588, | |
| 12713 | |
| ], | |
| "CO2H-Et deprotection": [ | |
| 3665, | |
| 15010, | |
| 2103, | |
| 20673, | |
| 26290 | |
| ], | |
| "N-Cbz deprotection": [ | |
| 548, | |
| 135, | |
| 432, | |
| 1161, | |
| 1470 | |
| ], | |
| "Sulfonic ester Schotten-Baumann": [ | |
| 10311, | |
| 6967, | |
| 16358, | |
| 12964, | |
| 15035 | |
| ], | |
| "Fischer-Speier esterification": [ | |
| 585, | |
| 1084, | |
| 571, | |
| 1010, | |
| 3051 | |
| ], | |
| "Bromo Buchwald-Hartwig amination": [ | |
| 9197, | |
| 8830, | |
| 4304, | |
| 9577, | |
| 7019 | |
| ], | |
| "Darzens bromination": [ | |
| 74, | |
| 51, | |
| 46, | |
| 28, | |
| 17 | |
| ], | |
| "Iodination": [ | |
| 2087, | |
| 2021, | |
| 372, | |
| 3095, | |
| 192 | |
| ], | |
| "Methyl esterification": [ | |
| 1796, | |
| 2504, | |
| 2621, | |
| 6916, | |
| 1040 | |
| ], | |
| "Iodo Sonogashira coupling": [ | |
| 3152, | |
| 3126, | |
| 3834, | |
| 2059, | |
| 94 | |
| ], | |
| "Ketone to alcohol reduction": [ | |
| 11145, | |
| 1876, | |
| 11169, | |
| 8797, | |
| 4371 | |
| ], | |
| "Iodo N-methylation": [ | |
| 12592, | |
| 10501, | |
| 5573, | |
| 1827, | |
| 4808 | |
| ], | |
| "Aldehyde Dess-Martin oxidation": [ | |
| 3561, | |
| 1295, | |
| 3716, | |
| 26, | |
| 2157 | |
| ], | |
| "Ketone reductive amination": [ | |
| 8201, | |
| 2927, | |
| 8317, | |
| 1743, | |
| 10244 | |
| ], | |
| "Keto alpha-alkylation": [ | |
| 2444, | |
| 4158, | |
| 4988, | |
| 1629, | |
| 1252 | |
| ], | |
| "Triflyloxy Miyaura boration": [ | |
| 191, | |
| 390, | |
| 82, | |
| 276, | |
| 398 | |
| ], | |
| "Chlorination": [ | |
| 4, | |
| 2655, | |
| 4002, | |
| 159, | |
| 916 | |
| ], | |
| "Chloro Miyaura boration": [ | |
| 371, | |
| 314, | |
| 245, | |
| 59, | |
| 246 | |
| ], | |
| "Ester hydrolysis": [ | |
| 1798, | |
| 1161, | |
| 161, | |
| 175, | |
| 1498 | |
| ], | |
| "O-TBDPS deprotection": [ | |
| 995, | |
| 1671, | |
| 141, | |
| 2002, | |
| 1557 | |
| ], | |
| "Grignard ester substitution": [ | |
| 136, | |
| 32, | |
| 121, | |
| 140, | |
| 42 | |
| ], | |
| "Bromo Suzuki coupling": [ | |
| 8685, | |
| 17290, | |
| 19876, | |
| 13865, | |
| 6940 | |
| ], | |
| "Iodo Stille reaction": [ | |
| 138, | |
| 176, | |
| 51, | |
| 182, | |
| 79 | |
| ], | |
| "Bromo Sonogashira coupling": [ | |
| 3268, | |
| 3059, | |
| 3588, | |
| 4239, | |
| 3698 | |
| ], | |
| "O-Bn deprotection": [ | |
| 495, | |
| 1015, | |
| 920, | |
| 262, | |
| 1384 | |
| ], | |
| "Chloro Sonogashira coupling": [ | |
| 21, | |
| 235, | |
| 225, | |
| 7, | |
| 72 | |
| ], | |
| "Alcohol + amine condensation": [ | |
| 1449, | |
| 1292, | |
| 120, | |
| 468, | |
| 138 | |
| ], | |
| "O-TBS deprotection": [ | |
| 7417, | |
| 257, | |
| 7042, | |
| 2706, | |
| 580 | |
| ], | |
| "Mitsunobu aryl ether synthesis": [ | |
| 8423, | |
| 3899, | |
| 4562, | |
| 10960, | |
| 7953 | |
| ], | |
| "Chloro Buchwald-Hartwig amination": [ | |
| 3510, | |
| 2167, | |
| 7744, | |
| 3981, | |
| 7749 | |
| ], | |
| "Weinreb amide synthesis": [ | |
| 3307, | |
| 1667, | |
| 779, | |
| 386, | |
| 397 | |
| ], | |
| "Iodo Grignard reaction": [ | |
| 168, | |
| 110, | |
| 90, | |
| 108, | |
| 105 | |
| ], | |
| "Bromo Miyaura boration": [ | |
| 7651, | |
| 887, | |
| 1612, | |
| 993, | |
| 6596 | |
| ], | |
| "Bromo Stille reaction": [ | |
| 745, | |
| 347, | |
| 819, | |
| 111, | |
| 254 | |
| ], | |
| "Chloro Suzuki coupling": [ | |
| 3139, | |
| 3116, | |
| 8786, | |
| 7350, | |
| 2296 | |
| ], | |
| "Carboxylic acid + amine condensation": [ | |
| 110593, | |
| 48100, | |
| 73018, | |
| 121275, | |
| 65485 | |
| ], | |
| "Darzens chlorination": [ | |
| 617, | |
| 3630, | |
| 4508, | |
| 802, | |
| 414 | |
| ], | |
| "Wohl-Ziegler bromination": [ | |
| 333, | |
| 276, | |
| 7, | |
| 47, | |
| 121 | |
| ], | |
| "Esterification": [ | |
| 1362, | |
| 3329, | |
| 3978, | |
| 3943, | |
| 1751 | |
| ], | |
| "Mitsunobu ester synthesis": [ | |
| 410, | |
| 60, | |
| 168, | |
| 388, | |
| 2 | |
| ], | |
| "Bromo Grignard preparation": [ | |
| 99, | |
| 67, | |
| 200, | |
| 116, | |
| 73 | |
| ], | |
| "O-TIPS deprotection": [ | |
| 433, | |
| 569, | |
| 498, | |
| 158, | |
| 194 | |
| ], | |
| "N-Cbz protection": [ | |
| 1215, | |
| 891, | |
| 3967, | |
| 239, | |
| 2372 | |
| ], | |
| "Bechamp reduction": [ | |
| 8883, | |
| 998, | |
| 5138, | |
| 936, | |
| 821 | |
| ], | |
| "Bromo N-alkylation": [ | |
| 38284, | |
| 31246, | |
| 32954, | |
| 60252, | |
| 55883 | |
| ], | |
| "Isocyanate + alcohol reaction": [ | |
| 2175, | |
| 644, | |
| 232, | |
| 2080, | |
| 328 | |
| ], | |
| "Carboxylic ester + amine reaction": [ | |
| 6089, | |
| 2245, | |
| 19498, | |
| 2226, | |
| 7707 | |
| ], | |
| "Mitsunobu imide reaction": [ | |
| 826, | |
| 245, | |
| 1166, | |
| 504, | |
| 1185 | |
| ], | |
| "Carboxy to carbamoyl": [ | |
| 4870, | |
| 325, | |
| 5073, | |
| 671, | |
| 3434 | |
| ], | |
| "Claisen-Schmidt condensation": [ | |
| 2692, | |
| 2390, | |
| 2315, | |
| 2141, | |
| 1295 | |
| ], | |
| "Amide Schotten-Baumann": [ | |
| 17089, | |
| 13386, | |
| 43891, | |
| 46936, | |
| 20590 | |
| ], | |
| "Carbamate Schotten-Baumann": [ | |
| 3910, | |
| 4351, | |
| 6484, | |
| 2144, | |
| 11004 | |
| ], | |
| "Chloro Stille reaction": [ | |
| 330, | |
| 153, | |
| 234, | |
| 161, | |
| 37 | |
| ], | |
| "Mesyloxy N-alkylation": [ | |
| 76, | |
| 3754, | |
| 5088, | |
| 4612, | |
| 819 | |
| ], | |
| "Methoxy to hydroxy": [ | |
| 600, | |
| 4404, | |
| 1746, | |
| 4144, | |
| 2172 | |
| ], | |
| "Knoevenagel condensation": [ | |
| 271, | |
| 1911, | |
| 714, | |
| 1804, | |
| 140 | |
| ], | |
| "Ester to alcohol reduction": [ | |
| 14405, | |
| 4002, | |
| 6054, | |
| 4669, | |
| 2584 | |
| ], | |
| "Wittig olefination": [ | |
| 3589, | |
| 6830, | |
| 4450, | |
| 5763, | |
| 2478 | |
| ], | |
| "Steglich esterification": [ | |
| 2505, | |
| 3305, | |
| 2678, | |
| 2166, | |
| 32 | |
| ], | |
| "Aldehyde reductive amination": [ | |
| 21884, | |
| 26774, | |
| 18173, | |
| 9810, | |
| 30531 | |
| ], | |
| "Chloro N-alkylation": [ | |
| 6788, | |
| 8800, | |
| 17332, | |
| 7564, | |
| 7014 | |
| ], | |
| "Chloro Grignard reaction": [ | |
| 1133, | |
| 318, | |
| 557, | |
| 577, | |
| 1238 | |
| ], | |
| "Williamson ether synthesis": [ | |
| 107, | |
| 367, | |
| 175, | |
| 104, | |
| 351 | |
| ], | |
| "Iodo Buchwald-Hartwig amination": [ | |
| 540, | |
| 1035, | |
| 1000, | |
| 514, | |
| 104 | |
| ], | |
| "Iodo Suzuki coupling": [ | |
| 756, | |
| 3469, | |
| 2266, | |
| 361, | |
| 29 | |
| ], | |
| "N-Boc protection": [ | |
| 10929, | |
| 4286, | |
| 8583, | |
| 5294, | |
| 14478 | |
| ], | |
| "N-Boc deprotection": [ | |
| 72309, | |
| 92493, | |
| 56057, | |
| 73519, | |
| 1267 | |
| ] | |
| } |