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1
+ {
2
+ "Gilman type conjugate addition": "3.11.89",
3
+ "Keto alpha-alkylation": "3.11.91",
4
+ "Ester to alcohol reduction": "7.4.1",
5
+ "O-Acetylation": "2.6.8",
6
+ "Alkene hydrogenation": "7.6.1",
7
+ "CO2H-Me deprotection": "6.2.2",
8
+ "Shiina macrolactonization": "2.6.33",
9
+ "N-Boc deprotection": "6.1.1",
10
+ "Carboxylic acid + amine condensation": "2.1.2",
11
+ "Williamson ether synthesis": "1.7.9",
12
+ "Ester Schotten-Baumann": "2.6.1",
13
+ "Amide Schotten-Baumann": "2.1.1",
14
+ "Other separation": "11.10",
15
+ "Ester hydrolysis": "9.7.61",
16
+ "O-TBS protection": "5.3.2",
17
+ "O-TBS deprotection": "6.3.2",
18
+ "Iodination": "10.1.4",
19
+ "Ketone reductive amination": "1.2.5",
20
+ "Iodo Suzuki coupling": "3.1.3",
21
+ "Nitro to amino": "7.1.1",
22
+ "Sandmeyer iodination": "9.7.99",
23
+ "Methyl esterification": "1.7.6",
24
+ "Amino to iodo": "9.7.10",
25
+ "Defluorination": "9.7.140",
26
+ "Iodo Miyaura boration": "9.7.78",
27
+ "Bromo Suzuki coupling": "3.1.1",
28
+ "Iodo to pinacolatoboranyl": "9.7.85",
29
+ "CDI urea synthesis": "2.3.7",
30
+ "Goldberg reaction": "1.3.23",
31
+ "Bromo Buchwald-Hartwig amination": "1.3.1",
32
+ "Bromo Grignard reaction": "3.7.2",
33
+ "Aldehyde reductive imination": "1.2.2",
34
+ "N-tBu sulfinyl deprotection": "6.1.22",
35
+ "Ketone amine condensation": "1.2.18",
36
+ "Carbamate Schotten-Baumann": "2.4.5",
37
+ "Bromo N-alkylation": "1.6.2",
38
+ "Chloro N-arylation": "1.3.7",
39
+ "Epoxide + amine coupling": "1.2.14",
40
+ "CO2H-Et deprotection": "6.2.1",
41
+ "Chloro Miyaura boration": "9.7.37",
42
+ "N-PMB deprotection": "6.1.11",
43
+ "Alkylimino-de-oxo-bisubstitution": "1.2.3",
44
+ "Chloro N-alkylation": "1.6.4",
45
+ "Ketone to alcohol reduction": "7.5.1",
46
+ "CO2H-tBu deprotection": "6.2.3",
47
+ "Friedel-Crafts acylation": "3.10.1",
48
+ "Trihaloacetyl + alcohol reaction": "2.6.29",
49
+ "Levy reaction": "2.3.3",
50
+ "Bromination": "10.1.1",
51
+ "Thiazole synthesis": "4.3.3",
52
+ "Isothiocyanate + amine thiourea coupling": "2.3.2",
53
+ "N-Bz deprotection": "6.1.2",
54
+ "Oxazole synthesis": "4.2.16",
55
+ "Bromo to azido": "9.7.23",
56
+ "Dioxolane synthesis": "4.2.20",
57
+ "Phosphate ester synthesis": "1.9.20",
58
+ "Iodo thioether synthesis": "1.8.15",
59
+ "Carbonylthiourea synthesis": "2.8.10",
60
+ "Sulfoxy thioether synthesis": "1.8.31",
61
+ "Methylation": "10.4.2",
62
+ "2-Thioxopyrimidin-4-one synthesis": "4.1.95",
63
+ "Bromo thioether synthesis": "1.8.12",
64
+ "Formaldehyde reductive amination": "1.2.10",
65
+ "Aryllithium carboxylation": "3.9.159",
66
+ "Sulfonamide Schotten-Baumann": "2.2.3",
67
+ "Reductive cyclopropane cleavage": "7.9.79",
68
+ "Aldehyde to acid oxidation": "8.8.3",
69
+ "Aldehyde reductive amination": "1.2.1",
70
+ "Carboxylation": "10.4.6",
71
+ "Carboxylic acid Schmidt reaction": "9.7.164",
72
+ "Racemization": "11.7",
73
+ "Phosphonamide Schotten-Baumann": "2.8.3",
74
+ "Chloro Suzuki coupling": "3.1.2",
75
+ "N-Fmoc protection": "5.1.3",
76
+ "Bromo N-arylation": "1.3.6",
77
+ "N-Boc protection": "5.1.1",
78
+ "Hydroxy to chloroformate": "9.7.321",
79
+ "Imidazole synthesis": "4.1.12",
80
+ "Methoxy to hydroxy": "6.3.7",
81
+ "Carboxylic acid + amidine condensation": "2.1.61",
82
+ "Nitrogen oxidation": "8.4.2",
83
+ "Mitsunobu aryl ether synthesis": "1.7.7",
84
+ "Iodo N-methylation": "1.1.3",
85
+ "Lindgren oxidation": "8.8.5",
86
+ "Bromo to methoxy": "9.7.31",
87
+ "Imidazo[1,2-a]pyrimidine synthesis": "4.1.193",
88
+ "Alkene acylation": "3.11.224",
89
+ "SNAr ether synthesis": "1.7.11",
90
+ "Palladium catalyzed cyanation": "9.7.462",
91
+ "Cyano to carbamoyl": "9.7.57",
92
+ "Vilsmeier-Haack reaction": "3.11.14",
93
+ "Iodo to cyano": "9.7.82",
94
+ "Carboxy to carbamoyl": "9.7.33",
95
+ "Bromo to pinacolatoboranyl": "9.7.32",
96
+ "Amination": "10.4.5",
97
+ "CO2H-tBu protection": "5.2.1",
98
+ "Carboxylic ester + amine reaction": "2.1.10",
99
+ "Krapcho decarboxylation": "9.7.127",
100
+ "CO2H-Bn deprotection": "6.2.4",
101
+ "Esterification": "2.6.2",
102
+ "Lactone alcoholysis": "1.7.76",
103
+ "Hydroxy to fluoro": "9.1.7",
104
+ "Fischer-Speier esterification": "2.6.3",
105
+ "Nitration": "10.2.1",
106
+ "Aza-Diels-Alder reaction": "4.1.80",
107
+ "N-dealkylation": "9.7.334",
108
+ "Aryl alpha alkylation": "3.11.252",
109
+ "Prilezhaev epoxidation": "4.2.8",
110
+ "N-Cbz deprotection": "6.1.3",
111
+ "Decarboxylation": "9.7.194",
112
+ "N-Acetylation": "2.1.7",
113
+ "Oxo to thioxo": "9.7.93",
114
+ "Ullmann thioether synthesis": "1.8.36",
115
+ "Lumiere-Barbier method": "2.1.78",
116
+ "Chlorination": "10.1.2",
117
+ "N-Ac deprotection": "6.1.4",
118
+ "Van Leusen oxazole synthesis": "4.2.29",
119
+ "Cyano to amidino": "9.7.181",
120
+ "N-Acyl amidine Schotten-Baumann": "2.1.62",
121
+ "Iodo Stille reaction": "3.4.5",
122
+ "Iodo to trifluoromethyl": "9.7.306",
123
+ "Alkane dehydrogenation": "8.8.18",
124
+ "Bromo Miyaura boration": "9.7.20",
125
+ "Carbamate + carboxylic acid reaction": "2.1.44",
126
+ "2,3-Quinoxalinedione synthesis": "4.1.67",
127
+ "Bromo Suzuki-type coupling": "3.1.5",
128
+ "Mitsunobu imide reaction": "1.4.1",
129
+ "Purification": "11.6",
130
+ "Sulfonic ester Schotten-Baumann": "2.7.2",
131
+ "Mesyloxy N-alkylation": "1.6.9",
132
+ "Carbonate Schotten-Baumann": "2.4.7",
133
+ "Carbonate + amine reaction": "2.4.9",
134
+ "O-Transcarbamation": "2.4.10",
135
+ "O-carbonate deprotection": "6.3.20",
136
+ "Alkene dihydroxylation": "10.4.9",
137
+ "O-acetonide protection": "5.3.7",
138
+ "O-Ac deprotection": "6.3.6",
139
+ "Menshutkin reaction": "1.1.2",
140
+ "Iodo Grignard reaction": "3.7.5",
141
+ "O-Bn protection": "5.3.1",
142
+ "Diels-Alder cycloaddition": "3.11.3",
143
+ "Hydroxy to triflyloxy": "1.7.5",
144
+ "Comins vinyl triflate synthesis": "9.7.418",
145
+ "Triflyloxy Miyaura boration": "9.7.103",
146
+ "Ketone dioxolane protection": "5.5.2",
147
+ "Aldehyde to alcohol reduction": "7.9.1",
148
+ "Ester halide coupling": "1.7.26",
149
+ "Ketone dioxolane deprotection": "6.5.3",
150
+ "Sulfanyl to sulfonyl": "8.2.2",
151
+ "Mesyloxy to bromo": "9.7.209",
152
+ "Triflyloxy Suzuki coupling": "3.1.4",
153
+ "Triflyloxy Suzuki-type coupling": "3.1.8",
154
+ "Chiral separation": "11.1",
155
+ "Aziridine + amine coupling": "1.2.13",
156
+ "CO2H-TBS deprotection": "6.2.5",
157
+ "Transetherification": "1.7.21",
158
+ "O-TSE deprotection": "6.3.23",
159
+ "Transamidation": "2.1.64",
160
+ "Trifluoroacetate salt formation": "11.8.5",
161
+ "Lemieux-Johnson oxidation": "8.5.3",
162
+ "Appel bromination": "9.1.1",
163
+ "Tosyloxy N-alkylation": "1.6.12",
164
+ "Tosyloxy to bromo": "9.7.287",
165
+ "Aldehyde to amide": "9.7.507",
166
+ "Deuteriation": "10.4.18",
167
+ "2,5-Pyrroledione synthesis": "4.1.2",
168
+ "N-Bn deprotection": "6.1.5",
169
+ "O-allyl deprotection": "6.3.28",
170
+ "Chloride salt formation": "11.8.3",
171
+ "Urea hydrolysis": "9.7.450",
172
+ "Carboxylic anhydride + amine reaction": "2.1.6",
173
+ "Ether + amine reaction": "1.2.20",
174
+ "Disuccinimidyl carbonate carbamate synthesis": "2.4.15",
175
+ "Iodo Sonogashira coupling": "3.3.4",
176
+ "Carbamate + amine reaction": "2.3.10",
177
+ "O-Bn deprotection": "6.3.1",
178
+ "Phosphate ester hydrolysis": "9.7.355",
179
+ "Boronic ester synthesis": "9.7.467",
180
+ "Phenol oxidation": "8.1.35",
181
+ "Hydroxy to chloro": "9.1.6",
182
+ "Carboxylic acid to acid chloride": "9.3.1",
183
+ "Isomerization": "11.5",
184
+ "Ketone amino hydroxy condensation": "1.7.48",
185
+ "Wurtz-Fittig coupling": "3.11.16",
186
+ "Hydroxy to bromo": "9.1.5",
187
+ "Sulfate ester N-alkylation": "1.1.10",
188
+ "Amino to bromo": "9.7.3",
189
+ "Sulfo to sulfamoyl": "2.2.7",
190
+ "Isocyanate + amine urea coupling": "2.3.1",
191
+ "Ketone reductive diamination": "1.2.26",
192
+ "Sulfinic acid + chloride reaction": "1.8.2",
193
+ "Chloro thioether synthesis": "1.8.13",
194
+ "Formic acid + amine condensation": "2.1.18",
195
+ "Iodo N-alkylation": "1.6.8",
196
+ "O-MOM protection": "5.3.6",
197
+ "N-Trityl deprotection": "6.1.24",
198
+ "Weinreb bromo coupling": "3.9.14",
199
+ "Knorr quinoline cyclization": "4.1.9",
200
+ "Pyridone to bromopyridine": "9.1.11",
201
+ "Deoxygenation": "9.7.60",
202
+ "Ketone aryl lithium addition": "3.9.79",
203
+ "Knoevenagel condensation": "3.11.34",
204
+ "Triflyloxy to pinacolatoboranyl": "9.7.104",
205
+ "Rosenmund von Braun cyanation": "9.7.95",
206
+ "Bechamp reduction": "7.1.3",
207
+ "Chlorocarbonyl to carbamoyl": "9.7.165",
208
+ "Horner-Wadsworth-Emmons reaction": "3.11.5",
209
+ "Sharpless asymmetric dihydroxylation": "10.4.12",
210
+ "Carboxy ester to carbamoyl": "9.7.128",
211
+ "4-Quinazolinone synthesis": "4.1.40",
212
+ "Amide to amine reduction": "7.2.1",
213
+ "Ketone Collins oxidation": "8.1.10",
214
+ "Iodo Menshutkin reaction": "1.1.7",
215
+ "Bromo elimination": "9.7.253",
216
+ "Chloro elimination": "9.7.254",
217
+ "Debromination": "9.7.139",
218
+ "Alcohol elimination": "9.5.4",
219
+ "Upjohn dihydroxylation": "10.4.11",
220
+ "Carboxylic anhydride alcoholysis": "2.6.21",
221
+ "Ester pyrolysis": "7.9.25",
222
+ "Ketone alkyl lithium addition": "3.9.77",
223
+ "Ring closing olefin metathesis": "3.9.121",
224
+ "Corey-Gilman-Ganem oxidation": "8.8.23",
225
+ "Mitsunobu ester synthesis": "2.6.20",
226
+ "Fluoro N-arylation": "1.3.8",
227
+ "Benzimidazole synthesis": "4.1.45",
228
+ "Amino to hydroxy": "9.7.173",
229
+ "Carbamate Curtius reaction": "2.4.1",
230
+ "Bromo to mesyl": "9.7.30",
231
+ "Nitrile + amine reaction": "2.5.5",
232
+ "Pyridone to chloropyridine": "9.1.14",
233
+ "Imidazo[1,2-a]pyridine synthesis": "4.1.86",
234
+ "Strecker ketone reaction": "3.11.11",
235
+ "N-Cbz protection": "5.1.2",
236
+ "Cyanoalkane alkylation": "3.11.52",
237
+ "N-Benzhydrylidene deprotection": "6.1.13",
238
+ "Hydroxy to amino": "9.7.183",
239
+ "Aldehyde Parikh-Doering oxidation": "8.1.28",
240
+ "Oxo to difluoro": "9.7.234",
241
+ "Riley oxidation": "8.8.14",
242
+ "Cyano to formyl": "9.7.182",
243
+ "Oxo to hydroxyimino": "9.7.92",
244
+ "Nitrile oxide 1,3-cycloaddition": "4.2.78",
245
+ "Chloro to iodo": "9.7.45",
246
+ "Jones acid oxidation": "8.3.2",
247
+ "Sulfonic acid elimination": "9.7.332",
248
+ "Bromo Sonogashira coupling": "3.3.2",
249
+ "Hydroxylation": "8.8.11",
250
+ "Hydroamination": "1.2.17",
251
+ "Keto alpha hydroxyimination": "1.2.33",
252
+ "Mesyl to hydroxy": "9.7.284",
253
+ "Keto alpha-acylation": "3.11.93",
254
+ "Carboxylic anhydride + hydrazine reaction": "2.1.12",
255
+ "Bromo Heck reaction": "3.2.1",
256
+ "Cyano to carboxy": "9.4.1",
257
+ "Formylation": "10.4.1",
258
+ "Carboxylic acid + hydrazine condensation": "2.1.3",
259
+ "O-acetonide deprotection": "6.3.16",
260
+ "1,3-Benzoxazol-2-one synthesis": "4.2.27",
261
+ "Chloro Grignard reaction": "3.7.3",
262
+ "Triflyloxy N-alkylation": "1.6.11",
263
+ "Chloropyridine to pyridone": "9.7.365",
264
+ "N-methylation": "1.1.4",
265
+ "Carboxylic acid + nitro reaction": "2.1.54",
266
+ "Alcohol to acid oxidation": "8.3.1",
267
+ "Alkyne + hydroxy reaction": "1.7.79",
268
+ "Carbamoyl to cyano": "9.5.1",
269
+ "O-TMS protection": "5.3.4",
270
+ "Wohl-Ziegler bromination": "10.1.5",
271
+ "Azido to amino": "9.7.13",
272
+ "Tetrazole synthesis": "4.1.24",
273
+ "Julia-Kocienski olefination": "3.9.47",
274
+ "Hirao coupling": "1.9.11",
275
+ "Darzens chlorination": "9.1.10",
276
+ "Diazomethane esterification": "1.7.2",
277
+ "Chloro Goldberg reaction": "1.3.31",
278
+ "N-TFA protection": "5.1.5",
279
+ "Chlorosulfonation": "10.3.2",
280
+ "Sulfanyl to sulfinyl": "8.2.1",
281
+ "Chloro to amino": "9.7.39",
282
+ "Ammonium cleavage": "11.9.4",
283
+ "N-TFA deprotection": "6.1.8",
284
+ "Carboxylic acid to alcohol reduction": "7.9.2",
285
+ "Aldehyde Swern oxidation": "8.1.23",
286
+ "Ketone reductive imination": "1.2.6",
287
+ "Aldehyde acetal deprotection": "6.5.9",
288
+ "N-THP deprotection": "6.1.9",
289
+ "Deamination": "9.7.147",
290
+ "O-Formylation": "2.6.24",
291
+ "Benzothiazole synthesis": "4.3.9",
292
+ "Negishi coupling": "3.5.3",
293
+ "Bromo Negishi preparation": "9.7.21",
294
+ "Weinreb amide synthesis": "2.1.9",
295
+ "Ullmann condensation": "1.7.8",
296
+ "Bromo Stille reaction": "3.4.3",
297
+ "Carbamate hydrolysis": "9.7.328",
298
+ "Chlorosulfonyl to sulfamoyl": "9.7.52",
299
+ "Kumada coupling": "3.5.2",
300
+ "Grignard imine reaction": "3.7.32",
301
+ "Henry reaction": "3.11.31",
302
+ "Bischler-Napieralski reaction": "4.1.5",
303
+ "Amide hydrolysis": "9.7.351",
304
+ "Formate + amine condensation": "2.1.42",
305
+ "Keto alpha-arylation": "3.11.86",
306
+ "Aziridine reduction": "7.9.60",
307
+ "Bose-Mitsunobu azidation": "9.7.394",
308
+ "Staudinger reduction": "9.7.102",
309
+ "Hydroxy to azido": "9.7.73",
310
+ "Amino to nitro": "8.4.1",
311
+ "Pyrimidine-2,4-dione synthesis": "4.1.54",
312
+ "N-SEM protection": "5.1.8",
313
+ "N-SEM deprotection": "6.1.18",
314
+ "Hydroxy to difluoromethoxy": "9.7.264",
315
+ "O-MOM deprotection": "6.3.8",
316
+ "Fluoro thioether synthesis": "1.8.14",
317
+ "Chloro Buchwald-Hartwig amination": "1.3.2",
318
+ "S-Thioester synthesis": "2.8.5",
319
+ "S-carbonyl deprotection": "6.4.1",
320
+ "Nitrile alpha acylation": "3.11.176",
321
+ "Pyrazolamine synthesis": "4.1.59",
322
+ "Pinner pyrimidine synthesis": "4.1.19",
323
+ "Oxa Davis oxaziridine oxidation": "8.8.24",
324
+ "Ketone Dess-Martin oxidation": "8.1.3",
325
+ "Corey-Itsuno reduction": "7.5.2",
326
+ "Ester ether coupling": "1.7.22",
327
+ "Nitrile reduction": "7.3.1",
328
+ "Chan-Lam alkylamine coupling": "1.1.1",
329
+ "Bromo alkoxycarbonylation": "2.6.10",
330
+ "Pinner reaction": "1.7.18",
331
+ "1,2,4-Oxadiazole synthesis": "4.2.2",
332
+ "Robinson-Gabriel synthesis": "4.2.100",
333
+ "Ketone ketal deprotection": "6.5.10",
334
+ "1,3,4-Oxadiazole synthesis": "4.2.3",
335
+ "Imide Schotten-Baumann": "2.1.59",
336
+ "Palladium-catalyzed direct arylation": "3.5.18",
337
+ "Knorr pyrazole synthesis": "4.1.8",
338
+ "Azide-alkyne Huisgen cycloaddition": "4.1.4",
339
+ "Alcohol to aldehyde oxidation": "8.1.4",
340
+ "Chloro Suzuki-type coupling": "3.1.6",
341
+ "Chloro alkoxycarbonylation": "2.6.11",
342
+ "Carboxylic ester + hydrazine reaction": "2.1.15",
343
+ "Iodo N-arylation": "1.3.9",
344
+ "Fluorination": "10.1.3",
345
+ "Phosphoramidate synthesis": "1.9.30",
346
+ "Weinreb ketone synthesis": "3.9.13",
347
+ "N-Besyl deprotection": "6.1.20",
348
+ "Iodo Buchwald-Hartwig amination": "1.3.3",
349
+ "Alcohol + amine condensation": "1.2.9",
350
+ "Hajos-Parrish-Eder-Sauer-Wiechert reaction": "3.11.243",
351
+ "Deiodination": "9.7.141",
352
+ "1,3-Dioxane synthesis": "4.2.39",
353
+ "Hydroxy to iodo": "9.1.8",
354
+ "O-benzylidene deprotection": "6.3.25",
355
+ "Silyl ether synthesis": "1.9.34",
356
+ "O-Piv protection": "5.3.12",
357
+ "Ketal reduction": "7.9.42",
358
+ "Bromo stannylation": "1.9.4",
359
+ "Aldehyde Dess-Martin oxidation": "8.1.2",
360
+ "Urea Schotten-Baumann": "2.3.9",
361
+ "Hydroxy to cyano": "9.7.371",
362
+ "Cyano to carbamato": "2.4.16",
363
+ "Ethenyl to formyl": "8.5.4",
364
+ "Oxime to amino": "9.7.286",
365
+ "Mesyloxy Kolbe nitrile synthesis": "9.7.236",
366
+ "N-Phth deprotection": "6.1.7",
367
+ "N-Tosyl deprotection": "6.1.16",
368
+ "Thioic acid to thiono ester": "9.7.347",
369
+ "Lithium ester saponification": "11.8.15",
370
+ "Carboxylic ester + nitro reaction": "2.1.53",
371
+ "Urea Curtius reaction": "2.3.6",
372
+ "Carboxylic acid + sulfonamide condensation": "2.1.5",
373
+ "Carboxylic ester + sulfonamide reaction": "2.1.17",
374
+ "Phosphonic P-alkylation": "1.9.40",
375
+ "Pinacolatoborylation": "10.4.17",
376
+ "Amino conjugate addition": "1.2.16",
377
+ "Ketone Jones oxidation": "8.1.7",
378
+ "Fluoro to azido": "9.7.106",
379
+ "Carboxylic acid + amide condensation": "2.1.57",
380
+ "Fluoro to bromo": "9.7.231",
381
+ "Ether halide coupling": "1.7.25",
382
+ "2-Pyrone to 2-pyridone": "4.1.194",
383
+ "Iodo Goldberg reaction": "1.3.32",
384
+ "Bromo to cyano": "9.7.25",
385
+ "Fluoro to chloro": "9.7.232",
386
+ "Mitsunobu amine reaction": "1.1.25",
387
+ "Ether hydrolysis": "9.7.326",
388
+ "Wittig olefination": "3.8.1",
389
+ "Alkene oxidation": "8.7.4",
390
+ "Amino to hydrazino": "9.7.9",
391
+ "Alkene hydration": "10.4.3",
392
+ "Tebbe olefination": "3.9.54",
393
+ "Pyridine to piperidine hydrogenation": "7.9.12",
394
+ "Ketone Swern oxidation": "8.1.24",
395
+ "Decarboxylative coupling": "3.9.41",
396
+ "Bischler-Mohlau indole synthesis": "4.1.64",
397
+ "Chloro to hydroxy": "9.7.44",
398
+ "Bromo to borono": "9.7.24",
399
+ "N-DMOB deprotection": "6.1.23",
400
+ "2-Imidazoline synthesis": "4.1.87",
401
+ "Iodo Suzuki-type coupling": "3.1.7",
402
+ "Fluoro to hydrazino": "9.7.65",
403
+ "Amino to formamido": "2.1.34",
404
+ "Formamido to isocyano": "9.7.68",
405
+ "N-Bn protection": "5.1.6",
406
+ "Bromo Grignard + ester reaction": "3.7.14",
407
+ "Kulinkovich reaction": "3.9.65",
408
+ "Amino thioether synthesis": "1.8.21",
409
+ "Triphosgene carbamate synthesis": "2.4.4",
410
+ "Hofmann reaction": "9.7.70",
411
+ "Ugi reaction": "2.1.28",
412
+ "Bromo Goldberg reaction": "1.3.30",
413
+ "Carbamate + carboxylic anhydride reaction": "2.1.83",
414
+ "N-tBu deprotection": "6.1.17",
415
+ "Bromo Grignard + nitrile ketone synthesis": "3.7.10",
416
+ "Aldol condensation": "3.11.2",
417
+ "Isoxazole synthesis": "4.2.4",
418
+ "Steglich esterification": "2.6.9",
419
+ "N-Ethyl carbamate deprotection": "6.1.29",
420
+ "Dicarbonate + amine reaction": "2.4.11",
421
+ "Pyrimidine synthesis": "4.1.48",
422
+ "Ketone dithiolane protection": "5.5.6",
423
+ "Chloro Sonogashira coupling": "3.3.3",
424
+ "Phosphonic ester synthesis": "1.7.59",
425
+ "Leimgruber-Batcho indole synthesis": "4.1.137",
426
+ "Indazole synthesis": "4.1.13",
427
+ "Borono to hydroxy": "9.7.16",
428
+ "Pyridine N-oxide to aminopyridine": "1.6.14",
429
+ "Hydroxy to methoxy": "1.7.4",
430
+ "Amino to chlorosulfonyl": "9.7.170",
431
+ "Cyano to thiocarbamoyl": "9.7.58",
432
+ "Imidazolecarbonyl to ester": "2.6.7",
433
+ "Phillips benzimidazole condensation": "4.1.16",
434
+ "Cyanoalkane arylation": "3.11.253",
435
+ "Aryl hydroxyalkylation": "3.11.164",
436
+ "Sulfonic anhydride + amine reaction": "2.2.9",
437
+ "O-SEM protection": "5.3.10",
438
+ "Aldehyde aryl lithium addition": "3.9.82",
439
+ "Aldehyde dioxolane deprotection": "6.5.2",
440
+ "Leuckart thiophenol reaction": "1.8.11",
441
+ "Alkyne TMS deprotection": "6.5.1",
442
+ "Iodo to borono": "9.7.81",
443
+ "Cadogan carbazole synthesis": "4.1.144",
444
+ "Alkene ether synthesis": "1.7.12",
445
+ "Amidine synthesis": "2.5.9",
446
+ "Acetal hydrolysis": "9.7.437",
447
+ "Ethyl esterification": "1.7.3",
448
+ "Acetal reduction": "7.9.41",
449
+ "Sulfonic ester hydrolysis": "9.7.356",
450
+ "Sodium salt formation": "11.8.8",
451
+ "Claisen-Schmidt condensation": "3.11.146",
452
+ "Clauson-Kaas reaction": "4.1.136",
453
+ "Paal-Knorr pyrrole synthesis": "4.1.14",
454
+ "Ortho Fries rearrangement": "3.11.24",
455
+ "Sulfo to chlorosulfonyl": "9.3.3",
456
+ "Chloro to hydrazino": "9.7.43",
457
+ "Chloro to iodo Finkelstein reaction": "9.7.46",
458
+ "Chloro Menshutkin reaction": "1.1.6",
459
+ "Pyrimidin-4-one synthesis": "4.1.130",
460
+ "Pyridine to dihydropyridine hydrogenation": "7.9.45",
461
+ "Alkyne to alkane hydrogenation": "7.7.1",
462
+ "Alcohol to ketone oxidation": "8.1.5",
463
+ "Chloro to azido": "9.7.40",
464
+ "Johnson-Corey-Chaykovsky epoxidation": "4.2.9",
465
+ "Epoxide + alcohol coupling": "1.7.17",
466
+ "Bromo Heck-type reaction": "3.2.5",
467
+ "Lithium Bouveault aldehyde synthesis": "3.9.27",
468
+ "Bromo to formyl": "9.7.142",
469
+ "O-Bz deprotection": "6.3.17",
470
+ "O-TMS deprotection": "6.3.4",
471
+ "Sulfinyl to sulfonyl": "8.2.4",
472
+ "Azido Tsuji-Trost reaction": "9.7.463",
473
+ "Oxirane synthesis": "4.2.35",
474
+ "Guanidine synthesis": "2.5.8",
475
+ "Ketone Corey-Suggs oxidation": "8.1.33",
476
+ "N-Fmoc deprotection": "6.1.6",
477
+ "Alkyne to alkene hydrogenation": "7.9.8",
478
+ "Other salt formation": "11.8.18",
479
+ "Allyl alcohol rearrangement": "9.7.484",
480
+ "Mukaiyama aldol addition": "3.11.110",
481
+ "Thioether hydrolysis": "9.7.569",
482
+ "Doebner-Miller reaction": "4.1.7",
483
+ "Pyridine synthesis": "4.1.49",
484
+ "Skraup reaction": "4.1.23",
485
+ "Amino to azido": "9.7.2",
486
+ "Luche reduction": "7.5.5",
487
+ "1,2,4-Triazole synthesis": "4.1.53",
488
+ "Garigipati amidine synthesis": "9.7.302",
489
+ "Amidino to aminoamidino": "9.7.466",
490
+ "Minisci reaction": "3.9.44",
491
+ "Fluoro to cyano": "9.7.163",
492
+ "Amino to chloro": "9.7.4",
493
+ "Grignard aryl ether reaction": "3.7.31",
494
+ "TCDI thiourea synthesis": "2.8.12",
495
+ "Benzimidazolethione synthesis": "4.1.94",
496
+ "Vinyl ether hydrolysis": "9.7.343",
497
+ "Pyrrolidine-2,5-dione synthesis": "4.1.177",
498
+ "Bartoli-Dobbs indole synthesis": "4.1.125",
499
+ "Hiyama coupling": "3.5.1",
500
+ "Indole synthesis": "4.1.42",
501
+ "N-Silylation": "9.7.552",
502
+ "Transesterification": "2.6.14",
503
+ "Thiourea to guanidino": "9.7.344",
504
+ "Rathke guanidine synthesis": "2.5.7",
505
+ "Amino to guanidino": "9.7.8",
506
+ "Diazoalkane etherification": "1.7.29",
507
+ "Decyanation": "7.9.62",
508
+ "Triflyloxy N-arylation": "1.3.10",
509
+ "Triflyloxy Buchwald-Hartwig amination": "1.3.4",
510
+ "Reductive ester cleavage": "7.9.66",
511
+ "Triflyloxy to cyano": "9.7.248",
512
+ "Phosphine oxide P-alkylation": "1.9.39",
513
+ "1,3,4-Thiadiazole synthesis": "4.3.8",
514
+ "Triple bond Diels-Alder": "3.11.12",
515
+ "Djerassi-Rylander oxidation": "8.5.5",
516
+ "Blaise reaction": "3.9.43",
517
+ "O-Tf deprotection": "6.3.26",
518
+ "Tertiary amine oxidation": "8.4.3",
519
+ "Imide to amine reduction": "7.2.2",
520
+ "Keto Claisen condensation": "3.11.133",
521
+ "Iodo Heck reaction": "3.2.3",
522
+ "Hydroxy to mesyloxy": "9.7.74",
523
+ "Secondary aldimine reduction": "7.3.4",
524
+ "Amino to carbamoyl chloride": "9.7.322",
525
+ "Baeyer-Villiger oxidation": "2.6.4",
526
+ "Triphosgene urea synthesis": "2.3.8",
527
+ "Doebner condensation": "3.11.155",
528
+ "Oxazolidin-2-one synthesis": "4.2.51",
529
+ "Carboxylic ester + azide reaction": "2.1.52",
530
+ "Benzotriazole synthesis": "4.1.47",
531
+ "Wolff-Kishner reduction": "7.9.6",
532
+ "Aryllithium alkylation": "3.9.132",
533
+ "Chloro to bromo": "9.7.179",
534
+ "Ullmann-type biaryl coupling": "3.11.13",
535
+ "Sulfoxy elimination": "9.7.526",
536
+ "Boekelheide reaction": "9.7.260",
537
+ "Hydroxy thioether synthesis": "1.8.33",
538
+ "Hydroxy to tosyloxy": "9.7.266",
539
+ "Bromo ketone Barbier reaction": "3.9.2",
540
+ "Sulfanyl to chlorosulfonyl": "9.7.134",
541
+ "Isocyanate + alcohol reaction": "2.4.2",
542
+ "Methoxypyridine to pyridone": "9.7.561",
543
+ "Carbonylurea synthesis": "2.3.21",
544
+ "Alkene thioether synthesis": "1.8.17",
545
+ "Mitsunobu thioether synthesis": "1.8.20",
546
+ "Chloro to sulfanyl": "9.7.136",
547
+ "Disulfide reduction": "7.9.14",
548
+ "Trifluoromethylation": "10.4.24",
549
+ "Thioxo to oxo": "9.7.615",
550
+ "Chan-Lam arylamine coupling": "1.3.5",
551
+ "Pyridine N-oxide to cyanopyridine": "3.11.100",
552
+ "Pyrazole synthesis": "4.1.60",
553
+ "Piperidin-2-one synthesis": "4.1.200",
554
+ "Cope elimination": "9.7.214",
555
+ "Carboxy to alkane reduction": "7.9.63",
556
+ "Hydroxylamine alkylation": "1.7.32",
557
+ "Carboxylic anhydride + sulfonamide reaction": "2.1.14",
558
+ "Imine hydrolysis": "9.7.148",
559
+ "Cyano to Hydroxyamidino": "9.7.259",
560
+ "Chloro to cyano": "9.7.41",
561
+ "O-PMB deprotection": "6.3.10",
562
+ "Johnson-Corey-Chaykovsky cyclopropane synthesis": "3.11.27",
563
+ "S-methylation": "1.8.6",
564
+ "Hydroxyamidino to amidino": "9.7.285",
565
+ "Debus-Radziszewski imidazole synthesis": "4.1.89",
566
+ "Trihalide hydrolysis": "9.7.433",
567
+ "2,4-Quinazolinedione synthesis": "4.1.68",
568
+ "Fluoro to hydroxy": "9.7.66",
569
+ "Benzofuran synthesis": "4.2.22",
570
+ "1,3-Benzoxazole synthesis": "4.2.17",
571
+ "Regitz diazo transfer": "9.7.230",
572
+ "Aminopyridine to pyridone": "9.7.330",
573
+ "Mesyl N-arylation": "1.3.12",
574
+ "Potassium ester saponification": "11.8.17",
575
+ "Secondary ketimine reduction": "7.3.5",
576
+ "Dechlorination": "9.7.59",
577
+ "Mesyloxy to azido": "9.7.303",
578
+ "Bromo aldehyde Barbier reaction": "3.9.1",
579
+ "Benzylic ketone oxidation": "8.6.2",
580
+ "Amino to ureido": "2.3.4",
581
+ "Amino to isocyanato": "9.7.11",
582
+ "Aldehyde Ruppert-Prakash trifluoromethylation": "3.11.81",
583
+ "Aldehyde amino hydroxy condensation": "1.7.47",
584
+ "Hydroxyiminomethyl to cyano": "9.5.5",
585
+ "Bromo to iodo": "9.7.28",
586
+ "Epoxide + thiol coupling": "1.8.10",
587
+ "Hydroxyimidamide alkylation": "1.7.35",
588
+ "Diazoalkane esterification": "1.7.28",
589
+ "O-Amination": "10.4.23",
590
+ "Ester to aldehyde reduction": "7.9.28",
591
+ "Benzylic acid oxidation": "8.6.11",
592
+ "Oxo Ing-Manske reaction": "9.7.447",
593
+ "Pyridine N-oxide to bromopyridine": "9.7.372",
594
+ "Bromo to fluoro": "9.7.178",
595
+ "N-TIPS deprotection": "6.1.34",
596
+ "Sharpless asymmetric aminohydroxylation": "10.4.19",
597
+ "Hydroxy amide alkylation": "1.7.36",
598
+ "Simmons-Smith-Furukawa reaction": "3.9.142",
599
+ "Pictet-Spengler reaction": "4.1.18",
600
+ "Amino to fluoro": "9.7.7",
601
+ "Mitsunobu sulfonamide reaction": "2.2.6",
602
+ "Pinacolatoboranyl to borono": "9.7.94",
603
+ "Parham cyclization": "3.9.88",
604
+ "N-Benzhydryl deprotection": "6.1.12",
605
+ "Ketone to alkane reduction": "7.9.4",
606
+ "Oxonium ether synthesis": "1.7.50",
607
+ "1,4-Dioxane synthesis": "4.2.40",
608
+ "Wolff-Kishner reduction, Huang-Minlon modification": "7.9.64",
609
+ "Petasis reaction": "3.11.51",
610
+ "N-Alloc deprotection": "6.1.25",
611
+ "Ether synthesis": "1.7.13",
612
+ "Cyano to hydroxy": "9.7.208",
613
+ "Acid anhydride hydrolysis": "9.7.335",
614
+ "Carboxy to chloro": "9.7.191",
615
+ "Carboxy to carbonazidoyl": "9.7.34",
616
+ "Chloroformate urea synthesis": "2.3.17",
617
+ "Alkene oxidative cleavage": "8.5.1",
618
+ "Iodo Heck-type reaction": "3.2.7",
619
+ "Carboxylic ester + imine reaction": "2.1.39",
620
+ "Thiazol-2-imine synthesis": "4.3.18",
621
+ "Bromo to amino": "9.7.22",
622
+ "Tosyloxy to azido": "9.7.366",
623
+ "Ketone Parikh-Doering oxidation": "8.1.29",
624
+ "Oxime to oxo": "9.7.150",
625
+ "Aldol addition": "3.11.1",
626
+ "Desulfurization": "9.7.499",
627
+ "Alkene bromination": "10.1.6",
628
+ "Acetoacetic ester synthesis": "3.11.84",
629
+ "Hydroxylamine acylation": "1.7.33",
630
+ "Aldehyde dithiane protection": "5.5.7",
631
+ "Iodo Corey-Seebach reaction": "3.9.73",
632
+ "Ketone dithiane deprotection": "6.5.8",
633
+ "Alkyne hydration": "9.7.458",
634
+ "Desulfonylation": "9.7.252",
635
+ "Pinacolatoboranyl to bromo": "9.7.187",
636
+ "Sulfinyl to sulfanyl": "7.9.22",
637
+ "Iodo alkoxycarbonylation": "2.6.13",
638
+ "Iodo Grignard + ester reaction": "3.7.17",
639
+ "Formyl to cyano": "9.7.166",
640
+ "Palladium Kumada coupling": "3.5.4",
641
+ "Aryllithium acylation": "3.9.144",
642
+ "Bouveault aldehyde synthesis": "3.9.25",
643
+ "Acetal reductive imination": "1.2.29",
644
+ "Sulfonation": "10.3.1",
645
+ "Carboxy to cyano": "9.7.268",
646
+ "Hydrazide Schotten-Baumann": "2.1.11",
647
+ "Epoxide to alpha hydroxy azido": "9.7.367",
648
+ "Fujiwara-Moritani reaction": "3.5.15",
649
+ "Chloro to fluoro": "9.7.42",
650
+ "Nitro to fluoro": "9.7.185",
651
+ "Sulfonic ester to amine": "9.7.342",
652
+ "Grignard Bouveault aldehyde synthesis": "3.9.26",
653
+ "Chlorosulfonyl to fluorosulfonyl": "9.7.51",
654
+ "Tosyloxy to fluoro": "9.7.289",
655
+ "N-sulfonyl cleavage": "9.7.614",
656
+ "Gould-Jacobs reaction": "4.1.126",
657
+ "Pyridone synthesis": "4.1.63",
658
+ "1,3-Hydrogen migration": "9.7.477",
659
+ "Amino to thioureido": "2.3.5",
660
+ "Claisen condensation": "3.11.41",
661
+ "Carboxylic acid + imine condensation": "2.1.37",
662
+ "2,3-Dihydro-1,3,4-thiadiazole synthesis": "4.3.20",
663
+ "Phosgene carbamate synthesis": "2.4.12",
664
+ "O-TBDPS deprotection": "6.3.29",
665
+ "Hydroxylamine hydrolysis": "9.7.369",
666
+ "Bromo to hydroxy": "9.7.27",
667
+ "Hydroxy amide arylation": "1.7.40",
668
+ "Aldehyde Collins oxidation": "8.1.9",
669
+ "Chromanone synthesis": "4.2.21",
670
+ "1,2,3-Triazole synthesis": "4.1.1",
671
+ "Sulfinic acid + bromide reaction": "1.8.1",
672
+ "Tosyloxy Kolbe nitrile synthesis": "9.7.238",
673
+ "Transureidation": "2.3.15",
674
+ "Chloro Kolbe nitrile synthesis": "9.7.157",
675
+ "Arndt-Eistert reaction": "3.11.102",
676
+ "Diazo to chloro": "9.7.115",
677
+ "Michael-Henry reaction": "3.11.76",
678
+ "Potassium salt formation": "11.8.7",
679
+ "[1,2,4]Triazolo[1,5-a]pyridine synthesis": "4.1.90",
680
+ "Pyrrolidine synthesis": "4.1.22",
681
+ "Acetoxy thioether synthesis": "1.8.16",
682
+ "Hydroxy + thioether reaction": "1.7.45",
683
+ "Tetrahydrofuran synthesis": "4.2.83",
684
+ "Malonic ester synthesis": "3.11.83",
685
+ "Phosphorus Menshutkin reaction": "1.9.12",
686
+ "Aziridine synthesis": "4.1.211",
687
+ "Mitsunobu amide reaction": "2.1.73",
688
+ "Indolizine synthesis": "4.1.256",
689
+ "N-arylation": "1.3.35",
690
+ "Ketal reductive amination": "1.2.41",
691
+ "Wolff rearrangement": "9.7.113",
692
+ "Diazoalkane amination": "1.1.27",
693
+ "Carboxy ester to ether reduction": "7.9.33",
694
+ "Acetal amine condensation": "1.2.21",
695
+ "Hydroxy + carbonate ether synthesis": "1.7.68",
696
+ "Chloro Stille reaction": "3.4.4",
697
+ "Phosphonate alpha acylation": "3.11.181",
698
+ "Hydroxy amide acylation": "1.7.39",
699
+ "O-acylhydroxylamine + amine reaction": "2.1.40",
700
+ "Epoxide + carboxy coupling": "2.6.18",
701
+ "Shi epoxidation": "4.2.99",
702
+ "Aza Paterno-Buchi reaction": "4.1.251",
703
+ "Michaelis-Arbuzov reaction": "1.9.1",
704
+ "N-Bus deprotection": "6.1.19",
705
+ "Morpholine synthesis": "4.2.5",
706
+ "Piperazine synthesis": "4.1.20",
707
+ "Piperidine synthesis": "4.1.21",
708
+ "Hemiaminal dehydration": "9.5.11",
709
+ "Pinnick oxidation": "8.8.6",
710
+ "Bromo cyclopropyl ring opening": "10.1.38",
711
+ "Rubottom oxidation": "8.7.1",
712
+ "Oxo to cyano": "9.7.224",
713
+ "Cyclic Beckmann rearrangement": "4.1.6",
714
+ "2-Pyrrolidone synthesis": "4.1.3",
715
+ "O-benzylidene protection": "5.3.13",
716
+ "Djerassi-Rylander amide oxidation": "8.8.26",
717
+ "Tosyloxy Suzuki coupling": "3.1.10",
718
+ "Nitro N-arylation": "1.3.15",
719
+ "O-THP deprotection": "6.3.9",
720
+ "Fischer indole synthesis": "4.1.34",
721
+ "Bromo to carboxy": "9.7.177",
722
+ "Lactone to lactam": "4.1.209",
723
+ "3,1-Benzoxazine-2,4-dione + amine reaction": "2.1.84",
724
+ "Mannich reaction": "3.11.6",
725
+ "Pyrrolo[2,3-c]pyridine synthesis": "4.1.196",
726
+ "O-Amide hydrolysis": "9.7.460",
727
+ "Formyl to ethynyl": "9.7.69",
728
+ "Alkyne TIPS deprotection": "6.5.17",
729
+ "N-Bz protection": "5.1.7",
730
+ "Acetal formation": "1.7.30",
731
+ "Chloro Grignard + ester reaction": "3.7.15",
732
+ "Aldehyde Jones oxidation": "8.1.6",
733
+ "Ketone Ruppert-Prakash trifluoromethylation": "3.11.82",
734
+ "Quinazoline synthesis": "4.1.71",
735
+ "2-Quinazolinone synthesis": "4.1.118",
736
+ "Phosgene urea synthesis": "2.3.13",
737
+ "Friedlander quinoline synthesis": "4.1.29",
738
+ "Burton trifluoromethylation": "3.9.99",
739
+ "Iodo to formyl": "9.7.145",
740
+ "O-TES protection": "5.3.9",
741
+ "Fluoro to methoxy": "9.7.67",
742
+ "Lactam synthesis": "4.1.57",
743
+ "[1,2]-Wittig rearrangement": "3.11.126",
744
+ "N-Transcarbamation": "2.4.14",
745
+ "N-Teoc deprotection": "6.1.27",
746
+ "Ozonolysis": "8.5.2",
747
+ "Aldehyde dioxolane protection": "5.5.1",
748
+ "O-Sulfonation": "10.3.4",
749
+ "Simmons-Smith reaction": "3.9.23",
750
+ "Borsche-Drechsel cyclization": "4.1.103",
751
+ "Borsche-Drechsel carbazole synthesis": "4.1.35",
752
+ "Sodium ester saponification": "11.8.16",
753
+ "Favorskii rearrangement": "3.11.29",
754
+ "Negishi-type coupling": "3.9.60",
755
+ "Borylation": "10.4.16",
756
+ "Strecker aldehyde reaction": "3.11.10",
757
+ "Duff reaction": "3.9.76",
758
+ "Alkene hydrobromination": "10.1.8",
759
+ "Carbonodithioate synthesis": "2.6.17",
760
+ "O-Trityl deprotection": "6.3.22",
761
+ "Myers asymmetric alkylation": "3.11.236",
762
+ "Pyrazolo[1,5-a]pyridine synthesis": "4.1.85",
763
+ "Imidic ester + amine reaction": "2.5.2",
764
+ "Bromo oxidative cleavage": "8.8.19",
765
+ "Curtius rearrangement": "9.7.56",
766
+ "Olefin metathesis": "3.9.12",
767
+ "Sulfonylation": "10.4.34",
768
+ "Trihalide to amide": "9.7.436",
769
+ "Iodo Takai olefination": "3.9.50",
770
+ "Mesylate salt formation": "11.8.4",
771
+ "Azomethine ylide 1,3-cycloaddition": "4.1.225",
772
+ "[1,2,4]Triazolo[1,5-a]pyrimidin-7-one synthesis": "4.1.97",
773
+ "Isoindolinone synthesis": "4.1.56",
774
+ "Grignard ester substitution": "3.7.19",
775
+ "Bromide salt formation": "11.8.2",
776
+ "Acetate salt formation": "11.8.1",
777
+ "Migita thioether synthesis": "1.8.7",
778
+ "Triflyloxy Sonogashira coupling": "3.3.5",
779
+ "Favorskii reaction": "3.11.39",
780
+ "Chloro Heck-type reaction": "3.2.6",
781
+ "Aryl hydrogenation": "7.8.1",
782
+ "Sulfonyl oxime synthesis": "9.7.441",
783
+ "Neber rearrangement": "9.7.393",
784
+ "Fluoropyridine to pyridone": "9.7.562",
785
+ "Niementowski quinazoline synthesis": "4.1.30",
786
+ "Chloropyridine to thiopyridone": "9.7.572",
787
+ "Thioamide hydrolysis": "9.7.573",
788
+ "Mesyloxy to chloro": "9.7.210",
789
+ "Mesyloxy to fluoro": "9.7.211",
790
+ "Mitsunobu beta dicarbonyl reaction": "3.11.122",
791
+ "Carboxylic anhydride synthesis": "2.6.19",
792
+ "Bromo to iodo Finkelstein reaction": "9.7.29",
793
+ "Chloroformate + nitro reaction": "2.4.17",
794
+ "Kolbe-Schmitt reaction": "3.11.45",
795
+ "Alder-Ene reaction": "3.11.134",
796
+ "Rieche formylation": "3.9.55",
797
+ "Aldehyde to alkane reduction": "7.9.19",
798
+ "Aldehyde reductive hydrazination": "1.2.42",
799
+ "Amine dehydrogenation": "8.8.30",
800
+ "Carboxylic acid + thiol condensation": "2.8.4",
801
+ "Sulfone alpha acylation": "3.11.168",
802
+ "Amino to isothiocyanato": "9.7.12",
803
+ "Grignard conjugate addition": "3.7.26",
804
+ "Bromo to chloro": "9.7.267",
805
+ "Tosyloxy to iodo": "9.7.290",
806
+ "Fluoro to amino": "9.7.64",
807
+ "Eschweiler-Clarke methylation": "1.2.4",
808
+ "Bromo to iodo aromatic Finkelstein reaction": "9.7.338",
809
+ "Knorr quinoline synthesis": "4.1.10",
810
+ "Pauson-Khand reaction": "3.9.35",
811
+ "Bromo to sulfanyl": "9.7.135",
812
+ "Pyridine N-oxide to pyridyl ester": "1.7.24",
813
+ "Gewald reaction": "4.3.4",
814
+ "Quinoxalinone synthesis": "4.1.83",
815
+ "Sulfonyl thioether synthesis": "1.8.30",
816
+ "O-methylation": "1.7.14",
817
+ "Iodo aldehyde Barbier reaction": "3.9.5",
818
+ "Amine oxide to amine reduction": "7.9.56",
819
+ "N-Formyl deprotection": "6.1.31",
820
+ "Bromo aminocarbonylation": "2.1.30",
821
+ "Carboxy ester to acid chloride": "9.7.331",
822
+ "Evans asymmetric aldol addition": "3.11.159",
823
+ "Iodolactonization": "4.2.15",
824
+ "Hydroxylamine arylation": "1.7.37",
825
+ "Appel chlorination": "9.1.2",
826
+ "Hydroxylamine + amine reaction": "1.1.14",
827
+ "Dieckmann condensation": "3.11.42",
828
+ "Stannylation": "1.9.8",
829
+ "Pyridine N-oxide to chloropyridine": "9.7.374",
830
+ "Chloro Heck reaction": "3.2.2",
831
+ "Japp-Klingemann reaction": "1.2.15",
832
+ "Ketone Schmidt reaction": "2.1.24",
833
+ "Feist-Benary pyrrole synthesis": "4.1.152",
834
+ "Isoxazole ring opening": "9.7.474",
835
+ "Gabriel-Isay condensation": "4.1.241",
836
+ "Dihydropyridine to pyridine": "8.8.31",
837
+ "Bromo Menshutkin reaction": "1.1.5",
838
+ "Isoquinolone synthesis": "4.1.215",
839
+ "Chloro to mesyl": "9.7.47",
840
+ "Aldehyde amine condensation": "1.2.19",
841
+ "Bromo to trifluoromethyl": "9.7.305",
842
+ "O-Tce deprotection": "6.3.27",
843
+ "Diketene + amine reaction": "2.1.56",
844
+ "Friedel-Crafts alkylation": "3.10.2",
845
+ "CO2H-iPr deprotection": "6.2.12",
846
+ "Sulfamate N-alkylamination": "1.6.16",
847
+ "Carbonate + amine reaction with decarboxylation": "1.9.21",
848
+ "Kulinkovich-Szymoniak reaction": "3.9.67",
849
+ "Carbonate urea synthesis": "2.3.16",
850
+ "Koenigs-Knorr reaction": "1.7.53",
851
+ "Bromo Kornblum oxidation": "8.8.7",
852
+ "Bouveault-Blanc aldehyde reduction": "7.9.75",
853
+ "Amide + alcohol reaction": "2.6.34",
854
+ "Vorbrueggen condensation": "1.6.15",
855
+ "Elbs tolyl persulfate oxidation": "8.6.4",
856
+ "Ester aryl lithium addition": "3.9.122",
857
+ "Nitrosylation": "10.4.15",
858
+ "Nitrosamine to hydrazine reduction": "7.9.11",
859
+ "Bromo Gabriel alkylation": "1.6.1",
860
+ "Amino Ing-Manske reaction": "9.7.446",
861
+ "Aldehyde Corey-Suggs oxidation": "8.1.32",
862
+ "Pfitzinger reaction": "4.1.32",
863
+ "Dehydration": "11.2",
864
+ "Borono to pinacolatoboranyl": "9.7.17",
865
+ "Carboxylic anhydride + amide reaction": "2.1.46",
866
+ "Fluoro elimination": "9.7.498",
867
+ "Retro Diels-Alder reaction": "9.7.395",
868
+ "Palladium arylhalide alkylation": "3.5.20",
869
+ "Stork enamine alkyation": "3.11.232",
870
+ "Aldehyde Cornforth oxidation": "8.1.14",
871
+ "Phosphoramide hydrolysis": "9.7.452",
872
+ "2-Oxazoline synthesis": "4.2.32",
873
+ "Sulfide + amine reaction": "1.1.26",
874
+ "Michael addition": "3.11.92",
875
+ "Arylsulfoxy N-alkylation": "1.1.18",
876
+ "Ketone Cornforth oxidation": "8.1.15",
877
+ "Thioamide desulfurization": "9.7.503",
878
+ "Hofmann rearrangement": "9.7.125",
879
+ "Buechner-Curtius-Schlotterbeck synthesis": "3.9.100",
880
+ "Fluoro N-alkylation": "1.6.6",
881
+ "Chloro to pinacolatoboranyl": "9.7.49",
882
+ "Bucherer-Bergs reaction": "4.1.117",
883
+ "Corey-Fuchs reaction step 1": "9.7.54",
884
+ "Corey-Fuchs reaction step 2": "9.7.55",
885
+ "O-TIPS protection": "5.3.3",
886
+ "O-TIPS deprotection": "6.3.3",
887
+ "Larock indole synthesis": "4.1.11",
888
+ "Aryl desilylation": "6.5.13",
889
+ "Pyrrole synthesis": "4.1.100",
890
+ "Pyridine to tetrahydropyridine hydrogenation": "7.9.46",
891
+ "Chloro Gabriel alkylation": "1.6.3",
892
+ "Benzothiophene synthesis": "4.3.6",
893
+ "Triflyloxy Stille reaction": "3.4.6",
894
+ "Epoxide reduction": "7.9.76",
895
+ "Baeyer oxindole synthesis": "4.1.161",
896
+ "Transcarbonation": "2.4.8",
897
+ "Urech cyanohydrin method": "9.7.262",
898
+ "Erlenmeyer-Ploechl azlactone synthesis": "4.2.105",
899
+ "Ketone Ley-Griffith oxidation": "8.1.26",
900
+ "Amino to cyano": "9.7.5",
901
+ "3-Pyridazinone synthesis": "4.1.70",
902
+ "Schmidt glycosylation": "1.7.52",
903
+ "Bergmann azlactone peptide synthesis": "2.1.81",
904
+ "Stolle synthesis": "4.1.223",
905
+ "Sandmeyer isatin synthesis": "4.1.222",
906
+ "Amino to pinacolatoboranyl": "9.7.311",
907
+ "Pyrazolone synthesis": "4.1.61",
908
+ "Lithium salt separation": "11.9.1",
909
+ "Bromo Kolbe nitrile synthesis": "9.7.155",
910
+ "Hydroxylamine reduction": "7.9.39",
911
+ "Bruylants amination": "1.2.24",
912
+ "Triphosgene carbonate synthesis": "2.4.6",
913
+ "N,O-acetonide deprotection": "6.5.18",
914
+ "Arylsulfoxy N-arylation": "1.3.18",
915
+ "Carbamate + sulfonic ester reaction": "1.9.23",
916
+ "Unrecognized": "4.2.45",
917
+ "Sulfonyl to sulfanyl": "7.9.23",
918
+ "O-Boc protection": "5.3.11",
919
+ "Van Leusen imidazole synthesis": "4.1.98",
920
+ "Tosyloxy N-arylation": "1.3.14",
921
+ "Houben-Hoesch reaction": "3.11.44",
922
+ "Sultone + amine reaction": "1.1.13",
923
+ "Ketone Leuckart reaction": "1.2.8",
924
+ "Ketal hydrolysis": "9.7.438",
925
+ "Acetyl to carboxy": "9.7.240",
926
+ "Dimroth triazole synthesis": "4.1.174",
927
+ "Bromo to hydrazino": "9.7.26",
928
+ "Nitro to bromo": "9.7.373",
929
+ "N-Methyl carbamate deprotection": "6.1.28",
930
+ "Diazo to bromo": "9.7.116",
931
+ "Menke nitration": "10.2.4",
932
+ "Barton-McCombie deoxygenation": "9.7.15",
933
+ "Pinacol rearrangement": "9.7.378",
934
+ "Thiazoline synthesis": "4.3.11",
935
+ "Nitro 1,3-cycloaddition": "4.2.96",
936
+ "Sodium salt separation": "11.9.3",
937
+ "Sulfone alpha alkylation": "3.11.177",
938
+ "Ketal formation": "1.7.31",
939
+ "Meinwald rearrangement": "9.7.492",
940
+ "Chan reduction": "7.9.37",
941
+ "Phosgene carbonate synthesis": "2.4.13",
942
+ "Meerwein-Ponndorf-Verley reduction": "7.5.4",
943
+ "Aziridine + alcohol coupling": "1.7.16",
944
+ "Carboxy hydroxy elimination": "9.7.524",
945
+ "Chlorosulfonyl to sulfanyl": "9.7.109",
946
+ "Simmons-Smith-Charette reaction": "3.9.116",
947
+ "Alkyne + aldehyde reaction": "3.11.38",
948
+ "Chloro to methoxy": "9.7.48",
949
+ "Oxime arylation": "1.7.38",
950
+ "Amino Tsuji-Trost reaction": "1.1.24",
951
+ "Epoxide hydrolysis": "9.7.464",
952
+ "Wurtz-type coupling": "3.11.17",
953
+ "Carboxy pyrolysis": "9.5.6",
954
+ "Enyne metathesis": "3.9.110",
955
+ "Aryliodide arylation": "3.11.207",
956
+ "Chloro to trifluoromethyl": "9.7.448",
957
+ "Nitro to hydroxyamino": "9.7.186",
958
+ "Pyrimidine-2,4,6-trione synthesis": "4.1.111",
959
+ "Sulfoxide alpha acylation": "3.11.167",
960
+ "[1,2,4]Triazolo[4,3-a]pyridine synthesis": "4.1.69",
961
+ "1,4-Dihydropyrazine-2,3-dione synthesis": "4.1.229",
962
+ "O-SEM deprotection": "6.3.13",
963
+ "Cyanohydrin reaction": "9.7.261",
964
+ "Isoquinoline synthesis": "4.1.216",
965
+ "Hurtley reaction": "3.9.115",
966
+ "Iodo to carboxy": "9.7.206",
967
+ "Nosyloxy N-alkylation": "1.6.13",
968
+ "Pyridine N-oxide rearrangement": "4.1.107",
969
+ "Biginelli reaction": "4.1.93",
970
+ "Decarbonylation": "9.7.207",
971
+ "Benzimidazolone synthesis": "4.1.46",
972
+ "Silane hydroxylation": "8.8.29",
973
+ "Aldehyde Ley-Griffith oxidation": "8.1.25",
974
+ "Hydration": "11.3",
975
+ "Urea to carbdiimide dehydration": "9.7.521",
976
+ "Primary ketimine reduction": "7.3.3",
977
+ "Azide-nitrile Huisgen cycloaddition": "4.1.79",
978
+ "Thiocarbonate synthesis": "2.8.11",
979
+ "Thiol elimination": "9.7.319",
980
+ "Chloro to carboxy": "9.7.204",
981
+ "Sulfinic acid + fluoride reaction": "1.8.3",
982
+ "Sulfinamide Schotten-Baumann": "2.2.1",
983
+ "Acid to acid chloride": "9.3.2",
984
+ "Lombardo olefination": "3.9.152",
985
+ "Ether to ester oxidation": "8.8.39",
986
+ "Hydroxy to imidazolecarbonyloxy": "2.6.6",
987
+ "Triflyloxy Menshutkin reaction": "1.1.8",
988
+ "Carboxylic acid to peroxyacid": "9.7.293",
989
+ "Iodo stannylation": "1.9.7",
990
+ "Ketal reductive imination": "1.2.30",
991
+ "Iodo to bromo": "9.7.336",
992
+ "Pyrazolidine-3,5-dione synthesis": "4.1.203",
993
+ "Lithium salt formation": "11.8.6",
994
+ "Fluoro to sulfanyl": "9.7.225",
995
+ "Ketone amino thia condensation": "1.8.26",
996
+ "Silane to bromo": "9.7.609",
997
+ "1,3,4-Oxadiazol-2-one synthesis": "4.2.28",
998
+ "N-Pbf deprotection": "6.1.39",
999
+ "Chlorocarbonyl to carboxy": "9.7.245",
1000
+ "CO2H-PMB deprotection": "6.2.10",
1001
+ "4-Pyrone to 4-pyridone": "4.1.195",
1002
+ "Dialkyl acetal reductive amination": "1.2.32",
1003
+ "Iodo to amino": "9.7.80",
1004
+ "Pyridine N-oxide synthesis": "4.1.267",
1005
+ "Craig synthesis": "9.7.421",
1006
+ "Guareschi-Thorpe condensation": "4.1.134",
1007
+ "Imidazolecarbonyl to amide": "2.1.27",
1008
+ "Alkene hydroxybromination": "10.1.25",
1009
+ "Sulfanyl to sulfonic acid oxidation": "8.2.7",
1010
+ "Sulfonic acid + amine reaction": "2.2.4",
1011
+ "Keto-enol tautomerisation": "11.11.1",
1012
+ "Oxa-Diels-Alder reaction": "4.2.23",
1013
+ "Conrad-Limpach quinoline synthesis": "4.1.27",
1014
+ "Diazoalkane 1,3-cycloaddition": "4.1.224",
1015
+ "Azo extrusion": "9.7.517",
1016
+ "Bromoform reaction": "9.7.241",
1017
+ "O-Piv deprotection": "6.3.24",
1018
+ "Delepine aldehyde oxidation": "8.8.2",
1019
+ "Chloro aminocarbonylation": "2.1.31",
1020
+ "Bromo to thiocyanato": "9.7.219",
1021
+ "Carboxy to imidazolecarbonyl": "2.1.26",
1022
+ "Formate salt formation": "11.8.14",
1023
+ "Amidine hydrolysis": "9.7.472",
1024
+ "Pyridine N-oxide reduction": "7.9.29",
1025
+ "Hydroxyimidamide acylation": "1.7.42",
1026
+ "Bisulfate salt formation": "11.8.10",
1027
+ "Carboxylic ester + amine + halide reaction": "2.1.45",
1028
+ "Iodo to mesyl": "9.7.227",
1029
+ "Demko-Sharpless reaction": "4.1.154",
1030
+ "Oxime alkylation": "1.7.34",
1031
+ "Sulfonium salt formation": "11.8.12",
1032
+ "Iodo aminocarbonylation": "2.1.33",
1033
+ "Camps quinoline synthesis": "4.1.25",
1034
+ "Fischer glycosidation": "1.7.73",
1035
+ "Chloro to iodo aromatic Finkelstein reaction": "9.7.339",
1036
+ "Potassium salt separation": "11.9.2",
1037
+ "Alkene ester synthesis": "2.6.30",
1038
+ "Pyrazolidin-3-one synthesis": "4.1.204",
1039
+ "Acid chloride + nitro reaction": "2.1.82",
1040
+ "Clive-Reich-Sharpless olefination": "9.7.320",
1041
+ "1,2,4-Triazine synthesis": "4.1.218",
1042
+ "Hydroxyimidamide arylation": "1.7.43",
1043
+ "Fluoro Goldberg reaction": "1.3.33",
1044
+ "Bromo to isothiocyanato": "9.7.358",
1045
+ "Sulfonamide + alcohol reaction": "2.2.5",
1046
+ "Chloro to chlorosulfonyl": "9.7.250",
1047
+ "Glycol cleavage": "8.1.31",
1048
+ "Chloro to sulfonato": "9.7.360",
1049
+ "Periodate cleavage": "8.1.18",
1050
+ "Ketone O-alkylation": "1.7.49",
1051
+ "Riley hydroxylation": "8.6.1",
1052
+ "Alkylsulfoxy N-alkylation": "1.1.15",
1053
+ "Carboxy to bromo": "9.7.190",
1054
+ "Ester + carboxylic acid reaction": "2.6.16",
1055
+ "Cyclic sulfate synthesis": "4.3.26",
1056
+ "3,1-Benzoxazine-2,4-dione synthesis": "4.2.26",
1057
+ "Chloro stannylation": "1.9.5",
1058
+ "Pyridine to pyridone": "8.8.44",
1059
+ "Sulfinylimine condensation": "3.11.90",
1060
+ "Chloro Grignard + nitrile ketone synthesis": "3.7.11",
1061
+ "N-Pmc deprotection": "6.1.40",
1062
+ "Methylsulfanyl to hydrazino": "9.7.88",
1063
+ "Transsulfuration": "1.8.29",
1064
+ "Bromo Corey-Seebach reaction": "3.9.69",
1065
+ "1,2,4-Oxadiazol-5-one synthesis": "4.2.1",
1066
+ "1,3-Dioxin-4-one synthesis": "4.2.106",
1067
+ "Albright-Goldman aldehyde oxidation": "8.1.54",
1068
+ "Carboxy to carboxy N-succinimide": "9.7.333",
1069
+ "Amino to nitroso": "8.4.4",
1070
+ "Mesyloxy to hydroxy": "9.7.87",
1071
+ "O-TES deprotection": "6.3.19",
1072
+ "Phosphorus Grignard reaction": "1.9.32",
1073
+ "Amino to keto oxidation": "8.4.13",
1074
+ "Iodo ketone Barbier reaction": "3.9.6",
1075
+ "O-Thioester synthesis": "2.8.6",
1076
+ "Baeyer-Villiger tritylation": "3.10.7",
1077
+ "Hydrazino to amino": "9.7.71",
1078
+ "Allyl to enone oxidation": "8.6.10",
1079
+ "Methyl to formyl": "8.8.1",
1080
+ "Disulfide coupling": "1.8.8",
1081
+ "Amino to mesylamino": "9.7.174",
1082
+ "Chlorosulfonyl to sulfinato": "9.7.110",
1083
+ "Sulfinic acid + iodide reaction": "1.8.4",
1084
+ "Blanc chloromethylation": "3.11.55",
1085
+ "Carbonylsulfonamide Schotten-Baumann": "2.2.11",
1086
+ "Alkene hydrosilylation": "10.4.20",
1087
+ "CO2H-TMS deprotection": "6.2.7",
1088
+ "Iodo to azido": "9.7.107",
1089
+ "Pyrrolidin-2-one synthesis": "4.1.141",
1090
+ "Cella-Piancatelli-Iwabuchi aldehyde oxidation": "8.1.44",
1091
+ "Barton vinyl iodine procedure": "9.7.592",
1092
+ "Carbonylsulfonohydrazide synthesis": "2.2.8",
1093
+ "Aldehyde reductive diamination": "1.2.27",
1094
+ "Sulfone cleavage": "9.7.540",
1095
+ "Meerwein arylation": "3.9.64",
1096
+ "Sulfoxide cleavage": "9.7.539",
1097
+ "Mesyl N-alkylation": "1.6.17",
1098
+ "Amino to amido oxidation": "8.8.34",
1099
+ "Mesyl to cyano": "9.7.184",
1100
+ "2 + 2 Cycloaddition": "3.11.166",
1101
+ "Cyanoacetic ester synthesis": "3.11.85",
1102
+ "Sulfonyl azide synthesis": "9.7.575",
1103
+ "Seyferth-Gilbert-Bestmann aldehyde homologation": "3.11.98",
1104
+ "Iodo elimination": "9.7.255",
1105
+ "Van Leusen reaction": "9.7.223",
1106
+ "Phosphorus oxidation": "8.8.16",
1107
+ "Sulfamidite synthesis": "1.9.29",
1108
+ "Fluoro sulfamate reaction": "9.7.511",
1109
+ "Dihydropyridazine to pyridazine oxidation": "8.4.14",
1110
+ "Hydroxy to N-succinimide carbonato": "1.7.20",
1111
+ "Triflyl Suzuki coupling": "3.1.15",
1112
+ "Halide Sommelet reaction": "8.1.36",
1113
+ "Iodo to hydroxy": "9.7.83",
1114
+ "Sulfonato to iodo Finkelstein reaction": "9.7.398",
1115
+ "Triflyloxy to azido": "9.7.304",
1116
+ "Pfitzner-Moffatt aldehyde oxidation": "8.1.37",
1117
+ "Chloro ketone Barbier reaction": "3.9.4",
1118
+ "Umemoto trifluoromethylation": "3.11.204",
1119
+ "Amino to ammonio": "9.7.1",
1120
+ "N-MOM deprotection": "6.1.32",
1121
+ "Carbamate rearrangement": "9.7.370",
1122
+ "Ganem oxidation": "8.1.53",
1123
+ "Carboxylic acid to aldehyde reduction": "7.9.88",
1124
+ "Ketone alkyl aluminium addition": "3.9.80",
1125
+ "Baylis-Hillman reaction": "3.11.46",
1126
+ "Mesyl to methoxy": "9.7.258",
1127
+ "Grignard + acid chloride ketone synthesis": "3.7.28",
1128
+ "Roskamp reaction": "3.9.148",
1129
+ "2-Methylpyridine acylation": "3.11.225",
1130
+ "Nickel Kumada coupling": "3.9.24",
1131
+ "Alkyl desilylation": "6.5.12",
1132
+ "Imine lithium addition": "3.9.166",
1133
+ "Algar-Flynn-Oyamada reaction": "4.2.56",
1134
+ "Alpha ketol rearrangement": "9.7.486",
1135
+ "S-Bn deprotection": "6.4.3",
1136
+ "Eschenmoser methylenation": "3.11.158",
1137
+ "Ketone alpha thioether synthesis": "1.8.18",
1138
+ "Barton decarboxylation": "9.7.195",
1139
+ "Bamford-Stevens reaction": "9.7.388",
1140
+ "Alcohol Ritter reaction": "2.1.21",
1141
+ "Metal halogen exchange": "9.7.424",
1142
+ "Para Claisen rearrangement": "3.11.189",
1143
+ "Chlorosulfonyl to sulfo": "9.7.130",
1144
+ "N-Benzylidene deprotection": "6.1.14",
1145
+ "Fluoro Sonogashira coupling": "3.3.6",
1146
+ "N-PMP deprotection": "6.1.10",
1147
+ "Knorr pyrrole synthesis": "4.1.73",
1148
+ "Feist-Benary furan synthesis": "4.2.59",
1149
+ "Iodo Kolbe nitrile synthesis": "9.7.161",
1150
+ "N-Aminoimide to diacylhydrazine rearrangement": "9.7.601",
1151
+ "Chan-Lam ether coupling": "1.7.1",
1152
+ "Criegee oxidation": "8.1.30",
1153
+ "Iodo alkoxylation": "1.7.63",
1154
+ "Iodo Gabriel alkylation": "1.6.7",
1155
+ "Weinreb iodo coupling": "3.9.17",
1156
+ "Keto oxidative cleavage": "8.8.41",
1157
+ "Ether elimination": "9.7.329",
1158
+ "Ketone reductive hydrazination": "1.2.43",
1159
+ "N-Mesyl deprotection": "6.1.21",
1160
+ "Phase transfer aryl alkylation": "3.11.250",
1161
+ "1,2,4-Triazole-3-thione synthesis": "4.1.99",
1162
+ "Coumarin synthesis": "4.2.24",
1163
+ "Julia olefination": "3.9.45",
1164
+ "1,7-Hydrogen migration": "9.7.479",
1165
+ "Cadiot-Chodkiewicz coupling": "3.9.18",
1166
+ "Cadiot-Chodkiewicz-type coupling": "3.9.22",
1167
+ "Bouveault-Blanc ketone reduction": "7.5.9",
1168
+ "1,3-Benzoxazine-2,4-dione synthesis": "4.2.47",
1169
+ "Kaiser-Johnson-Middleton dinitrile cyclization": "4.1.120",
1170
+ "Saegusa oxidation": "8.8.21",
1171
+ "Nickel Negishi coupling": "3.9.59",
1172
+ "Pechmann condensation": "4.2.37",
1173
+ "Newman-Kwart rearrangement": "9.7.90",
1174
+ "S-thiocarbamate deprotection": "6.4.2",
1175
+ "von Braun amide degradation": "9.7.413",
1176
+ "Aryloxy N-arylation": "1.3.16",
1177
+ "Pyrazolo[1,5-a]pyrimidine synthesis": "4.1.72",
1178
+ "Ketone Sarett oxidation": "8.1.13",
1179
+ "5,6-Dihydro-1,3-oxazine synthesis": "4.2.89",
1180
+ "Amino to diazonio": "9.7.6",
1181
+ "Urech hydantoin synthesis": "4.1.115",
1182
+ "N-sulfinyl cleavage": "9.7.613",
1183
+ "Cyanoamine reaction": "9.7.551",
1184
+ "Hydantoin synthesis": "4.1.116",
1185
+ "Alkene chlorination": "10.1.7",
1186
+ "Azo coupling": "1.3.25",
1187
+ "Cyclo dehydrogenation coupling": "3.11.199",
1188
+ "Nitroso to amino reduction": "7.9.5",
1189
+ "Thiirane + amine coupling": "1.1.30",
1190
+ "Acyclic Beckmann rearrangement": "2.8.1",
1191
+ "Bailey peptide synthesis": "2.1.80",
1192
+ "Tosyloxy Suzuki-type coupling": "3.1.12",
1193
+ "Ketone alkyne lithium addition": "3.9.78",
1194
+ "Hydrostannylation": "1.9.3",
1195
+ "Murahashi coupling": "3.5.14",
1196
+ "Nitrate ester synthesis": "1.9.22",
1197
+ "Sharpless epoxidation": "4.2.42",
1198
+ "Ethenyl to acetyl": "8.7.3",
1199
+ "Pyrazine to piperazine hydrogenation": "7.9.13",
1200
+ "Ketone nitro condensation": "1.2.28",
1201
+ "Pummerer rearrangement": "9.7.217",
1202
+ "Aza-Bargellini reaction": "3.11.139",
1203
+ "1,3,2-Dioxathiane 2-oxide synthesis": "4.3.34",
1204
+ "Aldehyde dioxane protection": "5.5.3",
1205
+ "Ether cleavage": "2.6.15",
1206
+ "Cella-Piancatelli-Iwabuchi ketone oxidation": "8.1.45",
1207
+ "Isothiazole synthesis": "4.3.7",
1208
+ "Bromo to boronic_ester": "9.7.611",
1209
+ "[1,2]-Aza-Wittig rearrangement": "3.11.128",
1210
+ "Ivanov reaction": "3.11.240",
1211
+ "Ketone dithiane protection": "5.5.8",
1212
+ "Nitro pyridine N-oxide reduction": "7.9.30",
1213
+ "Michaelis-Becker reaction": "1.9.45",
1214
+ "Thioxo to imino": "9.7.291",
1215
+ "Sulfinic ester Schotten-Baumann": "2.7.1",
1216
+ "Amine metallation": "9.7.473",
1217
+ "Betti reaction": "3.11.63",
1218
+ "Conia-ene reaction": "3.11.94",
1219
+ "Bromo to chlorosulfonyl": "9.7.249",
1220
+ "Triflyloxy Heck reaction": "3.2.4",
1221
+ "N-TMS deprotection": "6.1.35",
1222
+ "McMurry coupling": "3.9.28",
1223
+ "Nitroalkane alkylation": "3.11.53",
1224
+ "N-Dimethylaminomethylene deprotection": "6.1.15",
1225
+ "1,2,3-Thiadiazole synthesis": "4.3.40",
1226
+ "Thiocyanato to sulfanyl": "9.7.188",
1227
+ "Bromo alkoxylation": "1.7.62",
1228
+ "Ethylene carbonate ether synthesis": "1.7.19",
1229
+ "Isocyanato to amino": "9.7.86",
1230
+ "Kostanecki acylation": "4.2.54",
1231
+ "Midland Alpine borane reduction": "7.5.12",
1232
+ "4,5-dihydro-1H-imidazole synthesis": "4.1.128",
1233
+ "Sulfinimidoyl to sulfonimidoyl": "8.2.3",
1234
+ "Iodo to methylsulfanyl": "9.7.84",
1235
+ "Lobry de Bruyn-van Ekenstein transformation": "9.7.496",
1236
+ "Zinc alkylation": "3.9.143",
1237
+ "Hydroxy to sulfanyl": "9.7.75",
1238
+ "Alkylsulfonyl N-arylation": "1.3.28",
1239
+ "Oxa Danishefsky cycloaddition": "4.2.67",
1240
+ "Sulfo reduction": "7.9.40",
1241
+ "Yamaguchi lactonization": "4.2.12",
1242
+ "Enone Hosomi-Sakurai reaction": "3.11.19",
1243
+ "Alcohol + amine to imine": "1.2.31",
1244
+ "Sulfamate aryl alkylamination": "3.11.213",
1245
+ "Amino to isocyano": "9.7.167",
1246
+ "Colvin alkyne synthesis": "3.9.104",
1247
+ "Freund-Gustavson cyclopropane synthesis": "3.11.79",
1248
+ "Aromatic Claisen rearrangement": "3.11.69",
1249
+ "Carboxyl extrusion": "9.7.519",
1250
+ "Albright-Goldman ketone oxidation": "8.1.55",
1251
+ "Tetrahydropyridine to pyridine": "8.8.32",
1252
+ "Epoxide ring opening": "9.7.563",
1253
+ "Ciamician-Dennstedt cyclopropane synthesis": "3.11.80",
1254
+ "Doering-LaFlamme allene synthesis, step 1": "3.9.109",
1255
+ "O-MEM deprotection": "6.3.18",
1256
+ "Diazonio to hydroxy": "9.7.124",
1257
+ "Cesium salt formation": "11.8.19",
1258
+ "Bromo formaldehyde Barbier reaction": "3.9.29",
1259
+ "Delepine reaction": "1.1.9",
1260
+ "Imidocarbonate + amine reaction": "2.3.11",
1261
+ "Sulfoxy Stille reaction": "3.4.8",
1262
+ "Diketo to alkane reduction": "7.9.38",
1263
+ "Indole + ketone condensation": "3.11.70",
1264
+ "Wagner-Meerwein rearrangement": "3.11.172",
1265
+ "Perkin alicyclic synthesis": "3.11.87",
1266
+ "Fluoro to carboxy": "9.7.205",
1267
+ "N-Phth protection": "5.1.4",
1268
+ "Ritter reaction": "2.1.19",
1269
+ "Pyran-4-one synthesis": "4.2.80",
1270
+ "Perkin reaction": "3.11.36",
1271
+ "Frankland preparation": "9.7.430",
1272
+ "Kornblum-DeLaMare rearrangement": "9.7.586",
1273
+ "4,5-Dihydropyrazole synthesis": "4.1.188",
1274
+ "Zinin reaction": "7.1.2",
1275
+ "1,2,4-Thiadiazole synthesis": "4.3.14",
1276
+ "Bromo Grignard preparation": "9.7.19",
1277
+ "Pyrazine synthesis": "4.1.58",
1278
+ "Keto alpha silylation": "1.9.35",
1279
+ "Morgan-Walls reaction": "4.1.214",
1280
+ "Hydrazino to azido": "9.7.432",
1281
+ "Carboxylic acid to acid fluoride": "9.7.340",
1282
+ "Pictet-Gams reaction": "4.1.213",
1283
+ "Chloro aldehyde Barbier reaction": "3.9.3",
1284
+ "Matteson homologation": "3.9.161",
1285
+ "Dithiocarbamate synthesis": "1.8.27",
1286
+ "1,2,4-Triazin-5-one synthesis": "4.1.178",
1287
+ "Azo reduction": "7.9.49",
1288
+ "Deutero to nitro": "10.2.5",
1289
+ "1,2,4-Triazol-3-one synthesis": "4.1.114",
1290
+ "Babler oxidation": "8.6.13",
1291
+ "Wacker-Tsuji oxidation": "8.7.2",
1292
+ "Nazarov cyclization": "3.11.33",
1293
+ "Iodo Grignard + nitrile ketone synthesis": "3.7.13",
1294
+ "Brosyloxy N-alkylation": "1.1.17",
1295
+ "Iodo Negishi preparation": "9.7.79",
1296
+ "Ing-Manske reaction": "9.7.445",
1297
+ "Alpha ketone rearrangement": "9.7.487",
1298
+ "Thioacetal reduction": "7.9.54",
1299
+ "Kishner diazomethane cyclopropane synthesis": "3.11.57",
1300
+ "Bouveault-Blanc reduction": "7.4.2",
1301
+ "Reformatsky reaction": "3.9.37",
1302
+ "Nitrogen chlorination": "10.1.32",
1303
+ "Groebke-Blackburn-Bienayme reaction": "4.1.121",
1304
+ "O-Tosyl deprotection": "6.3.11",
1305
+ "Mesyloxy to iodo": "9.7.212",
1306
+ "Alkyne to alpha diketone oxidation": "8.7.6",
1307
+ "Selenophene synthesis": "4.4.1",
1308
+ "Scholl reaction": "3.10.3",
1309
+ "Pyrazolo[3,4-b]pyridine synthesis": "4.1.187",
1310
+ "Chloro Kornblum oxidation": "8.8.8",
1311
+ "Chloro to oxo oxidation": "8.1.21",
1312
+ "Iodide salt formation": "11.8.11",
1313
+ "Niementowski quinoline synthesis, 2nd step": "4.1.258",
1314
+ "Phosphinic P-alkylation": "1.9.38",
1315
+ "Nitro to chloro": "9.7.375",
1316
+ "1,3-Dithiane synthesis": "4.3.30",
1317
+ "Grignard acetal reaction": "3.7.24",
1318
+ "Isochroman-1-one synthesis": "4.2.76",
1319
+ "Pyrimidine-4,6-dione synthesis": "4.1.113",
1320
+ "Thioimidic ester + amine reaction": "2.5.4",
1321
+ "Carboxy to azido": "9.7.368",
1322
+ "Carbonate hydrolysis": "9.7.327",
1323
+ "Double bond migration": "9.7.444",
1324
+ "Quinone reduction": "7.5.8",
1325
+ "McLoughlin-Thrower trifluoromethylation": "3.9.128",
1326
+ "Reimer-Tiemann formylation": "10.4.8",
1327
+ "Aldehyde amino thia condensation": "1.8.25",
1328
+ "Brackeen imidazole synthesis": "4.1.169",
1329
+ "Phosphinic ester synthesis": "1.7.58",
1330
+ "Jocic ether reaction": "1.7.72",
1331
+ "Mesyloxy N-arylation": "1.3.13",
1332
+ "Dakin reaction": "8.8.17",
1333
+ "Carboxylic anhydride reduction": "7.9.27",
1334
+ "Robinson annulation": "3.11.7",
1335
+ "Sandmeyer bromination": "9.7.96",
1336
+ "2-Thioxoimidazolidin-4-one synthesis": "4.1.183",
1337
+ "Frankland reaction": "3.9.114",
1338
+ "Aldehyde alkyl lithium addition": "3.9.83",
1339
+ "Oxime to nitro": "8.4.9",
1340
+ "Oxime acylation": "1.7.41",
1341
+ "Carboxylic acid + thioamide condensation": "2.1.58",
1342
+ "Thorpe reaction": "3.11.229",
1343
+ "Chloroform reaction": "9.7.242",
1344
+ "Isocyanate + amine + halide urea coupling": "2.3.18",
1345
+ "Piperidine to pyridine": "8.8.33",
1346
+ "Perkin condensation": "3.11.35",
1347
+ "Formaldehyde reductive imination": "1.2.11",
1348
+ "Iminium hydrolysis": "9.7.149",
1349
+ "Dimroth rearrangement": "9.7.381",
1350
+ "Pyridine C,N-addition": "3.11.101",
1351
+ "Oxidative decarboxylation": "8.8.40",
1352
+ "Trichloromethanesulfoxy N-alkylation": "1.1.16",
1353
+ "Trihalide to ester": "9.7.434",
1354
+ "Stetter reaction": "3.11.78",
1355
+ "Paal-Knorr furan synthesis": "4.2.6",
1356
+ "Sandmeyer chlorination": "9.7.97",
1357
+ "Carboxy to fluoro": "9.7.192",
1358
+ "Ziegler alkylation": "3.9.129",
1359
+ "Ammonium ether synthesis": "1.7.64",
1360
+ "Alkene hydrochlorination": "10.1.9",
1361
+ "CO2H-Bz deprotection": "6.2.11",
1362
+ "1,2-Benzoxazole synthesis": "4.2.11",
1363
+ "Fukuyama reduction": "7.9.16",
1364
+ "Pyridone to cyanopyridine": "9.7.565",
1365
+ "Pyridone to methoxypyridine": "1.7.70",
1366
+ "Iodo to chloro": "9.7.337",
1367
+ "Boord olefin synthesis": "3.9.97",
1368
+ "Chloro Grignard preparation": "9.7.36",
1369
+ "Grieco elimination": "9.5.12",
1370
+ "Tamao oxidation": "8.8.20",
1371
+ "Sulfanyl to bromo": "9.7.608",
1372
+ "3,1-Benzoxazin-4-one synthesis": "4.2.18",
1373
+ "Bromo lactone ring opening": "10.1.37",
1374
+ "Madelung indole synthesis": "4.1.122",
1375
+ "Silyl ether + amine reaction": "1.1.12",
1376
+ "Wittig-type olefination": "3.8.2",
1377
+ "Diketene + alcohol reaction": "2.6.23",
1378
+ "Thiirane synthesis": "4.3.19",
1379
+ "Carbonothioato to chloroformato": "9.7.475",
1380
+ "Dithiane Gewald reaction": "4.3.12",
1381
+ "Iodo to sulfanyl": "9.7.137",
1382
+ "Chromone cyclization": "4.2.50",
1383
+ "Amadori rearrangement": "1.1.19",
1384
+ "Azide-alkene Huisgen cycloaddition": "4.1.226",
1385
+ "Nitrosothiol synthesis": "9.7.470",
1386
+ "Oxazolidin-5-one synthesis": "4.2.71",
1387
+ "Piperidine-2,5-dione synthesis": "4.1.201",
1388
+ "Amino to hydroxylamino": "8.4.11",
1389
+ "Alkyne to alkene bromination": "10.1.11",
1390
+ "Hydroxy Tsuji-Trost reaction": "1.7.51",
1391
+ "Caglioti reaction": "7.9.36",
1392
+ "Nitrogen bromination": "10.1.33",
1393
+ "Chloro to formyl": "9.7.143",
1394
+ "Chloro to isothiocyanato": "9.7.226",
1395
+ "Chloro cyclopropyl ring opening": "10.1.39",
1396
+ "Sulfonic ester + alcohol reaction": "1.7.27",
1397
+ "Forster-Decker amine synthesis": "1.1.21",
1398
+ "Mesyloxy to cyano": "9.7.133",
1399
+ "Yamaguchi esterification": "2.6.5",
1400
+ "Fluoro to iodo": "9.7.233",
1401
+ "Pomeranz-Fritsch reaction": "4.1.65",
1402
+ "Aldehyde + hydroxylamine reaction": "1.9.48",
1403
+ "Peroxy cleavage": "7.9.65",
1404
+ "Hemetsberger indole synthesis": "4.1.108",
1405
+ "1,3,2-Dioxathiolane 2-oxide synthesis": "4.3.33",
1406
+ "Nef reaction": "9.7.89",
1407
+ "Aldehyde dithiane deprotection": "6.5.7",
1408
+ "Thiazolidin-4-one synthesis": "4.3.13",
1409
+ "Payne epoxidation": "4.2.82",
1410
+ "2-Benzofuranone synthesis": "4.2.60",
1411
+ "N-Trichloroacetyl deprotection": "6.1.30",
1412
+ "Still-Gennari modified Horner-Wadsworth-Emmons reaction": "3.11.251",
1413
+ "Sulfonyl to sulfinyl": "7.9.24",
1414
+ "Halohosphate to phosphonate": "1.9.47",
1415
+ "Pyridone to aminopyridine": "9.7.566",
1416
+ "Birch reduction": "7.9.15",
1417
+ "Sulfonic ester synthesis": "9.7.357",
1418
+ "Carroll rearrangement": "3.11.121",
1419
+ "Ketone alpha selenoether synthesis": "1.9.18",
1420
+ "Aniline to quinone oxidation": "8.4.8",
1421
+ "Keto azide condensation": "1.2.37",
1422
+ "N,O-cycloaddition": "4.2.79",
1423
+ "Azirine synthesis": "4.1.176",
1424
+ "Oxa Pictet-Spengler reaction": "4.2.7",
1425
+ "Curtius degradation": "9.7.257",
1426
+ "Sulfate salt formation": "11.8.9",
1427
+ "Nitro N,C-migration": "9.7.600",
1428
+ "Ketone dithiolane deprotection": "6.5.6",
1429
+ "Epoxide + phosphate coupling": "1.7.75",
1430
+ "Sulfonothioate thioether synthesis": "1.8.34",
1431
+ "Thiophene synthesis": "4.3.5",
1432
+ "Norrish type II reaction": "9.7.595",
1433
+ "Sulfenamide synthesis": "1.9.37",
1434
+ "Davis-Beirut reaction": "4.1.173",
1435
+ "Dihydropyrimidone synthesis": "4.1.78",
1436
+ "Silyl ether deprotection": "6.3.5",
1437
+ "Flood reaction": "9.7.428",
1438
+ "Alkyne trimerization": "3.9.91",
1439
+ "Fleming-Tamao oxidation": "8.8.4",
1440
+ "Imine Hosomi-Sakurai reaction": "3.11.21",
1441
+ "1,3-Oxazinane synthesis": "4.2.44",
1442
+ "Grieco three component condensation": "4.1.247",
1443
+ "Gabriel-Colman rearrangement": "4.1.248",
1444
+ "Johnson-Corey-Chaykovsky aziridine synthesis": "4.1.33",
1445
+ "N-TBS deprotection": "6.1.33",
1446
+ "N-TBDPS deprotection": "6.1.36",
1447
+ "Bargellini reaction": "3.11.138",
1448
+ "Ketal amine condensation": "1.2.22",
1449
+ "Bucherer carbazole synthesis": "4.1.102",
1450
+ "Zincke nitration": "9.7.105",
1451
+ "Nitrogen hydroxylation": "8.4.15",
1452
+ "Ketene S,S-acetal synthesis": "3.11.54",
1453
+ "Amino elimination": "9.7.558",
1454
+ "Baudisch reaction": "10.4.14",
1455
+ "Piancatelli rearrangement": "3.11.130",
1456
+ "Aldehyde Darzens reaction": "4.2.33",
1457
+ "Boulton-Katrizky rearrangement": "9.7.411",
1458
+ "Guanidine hydrolysis": "9.7.345",
1459
+ "Noyori asymmetric hydrogenation": "7.5.3",
1460
+ "Eglinton reaction": "3.9.19",
1461
+ "Aldehyde Corey-Seebach reaction": "3.9.68",
1462
+ "Liebeskind-Srogl coupling": "3.5.11",
1463
+ "Appel oxazoline synthesis": "4.2.61",
1464
+ "Acetal reductive diamination": "1.2.36",
1465
+ "Amino to sulfanyl": "9.7.138",
1466
+ "Aldehyde alkyne amine reaction": "3.9.124",
1467
+ "Peroxy ether synthesis": "1.7.56",
1468
+ "Benary reaction": "3.9.89",
1469
+ "Pechmann pyrazole synthesis": "4.1.15",
1470
+ "Bromolactonization": "4.2.13",
1471
+ "Hydroformylation": "3.9.34",
1472
+ "Ketone dioxane protection": "5.5.4",
1473
+ "Cyclopropane ring expansion": "3.11.174",
1474
+ "Hammick reaction": "3.11.43",
1475
+ "Sulfinyl elimination": "9.7.505",
1476
+ "Bromo Hunsdiecker reaction": "9.7.200",
1477
+ "Thia Davis oxaziridine oxidation": "8.2.5",
1478
+ "Norrish-Yang cyclization": "3.11.221",
1479
+ "Formyl Tsuji-Wilkinson decarbonylation": "9.7.279",
1480
+ "Modified Ing-Manske reaction": "9.7.442",
1481
+ "Aldehyde Hosomi-Sakurai reaction": "3.11.26",
1482
+ "Alkyne to alkene chlorination": "10.1.13",
1483
+ "Kharasch addition": "3.11.113",
1484
+ "Diol elimination": "9.7.534",
1485
+ "Deutero to iodo": "10.1.22",
1486
+ "Tosyloxy to chloro": "9.7.288",
1487
+ "Corey-Nicolaou macrolactonization": "4.2.65",
1488
+ "Triflyloxy stannylation": "1.9.13",
1489
+ "Isocyanato to amino reduction": "7.9.67",
1490
+ "Para Fries rearrangement": "3.11.25",
1491
+ "Alkyne + formaldehyde reaction": "3.11.37",
1492
+ "Palladium-catalyzed borane coupling": "3.5.19",
1493
+ "Alkyne TES deprotection": "6.5.16",
1494
+ "Triflyloxy Hiyama coupling": "3.5.7",
1495
+ "Cyanoamine to urea": "9.7.606",
1496
+ "Darzens bromination": "9.1.9",
1497
+ "Hydrazino to bromo": "9.7.72",
1498
+ "Iodo lactone ring opening": "10.1.36",
1499
+ "Isothiocyanate + alkene reaction": "3.11.179",
1500
+ "Iodo to nitro": "9.7.353",
1501
+ "Salol reaction": "2.1.76",
1502
+ "Hofmann-Martius rearrangement": "3.11.234",
1503
+ "Pyrrolidinium synthesis": "4.1.119",
1504
+ "Stille-Kelly coupling": "3.4.2",
1505
+ "Blanc bromomethylation": "3.11.56",
1506
+ "Bromo to oxo oxidation": "8.1.1",
1507
+ "Amide O-alkylation": "1.7.77",
1508
+ "Urea + ester + halide reaction": "2.1.74",
1509
+ "Hydroxy sulfamate reaction": "9.7.515",
1510
+ "Bromo to nitro": "9.7.352",
1511
+ "Imide to amine cleavage": "7.2.3",
1512
+ "Amino to sulfo": "9.7.171",
1513
+ "Baker-Venkataraman flavone synthesis": "4.2.63",
1514
+ "Trihaloacetyl hydrolysis": "9.7.508",
1515
+ "Knunyants fluoroalkylation": "3.11.32",
1516
+ "Seyferth-Gilbert aldehyde homologation": "3.11.99",
1517
+ "Hydroxamic acid/ester Schotten-Baumann": "2.1.41",
1518
+ "4-Oxazolone synthesis": "4.2.87",
1519
+ "Benzylic Davis oxaziridine oxidation": "8.6.6",
1520
+ "Frater-Seebach alkylation": "3.11.244",
1521
+ "Bismuth O-arylation": "1.7.65",
1522
+ "Petasis olefination": "3.9.151",
1523
+ "Strecker amino acid synthesis": "3.11.231",
1524
+ "N-Troc deprotection": "6.1.26",
1525
+ "Chloro Gabriel synthesis": "9.7.35",
1526
+ "Phosphate ester N-alkylation": "1.1.11",
1527
+ "Imine-enamine tautomerisation": "11.11.3",
1528
+ "CO2H-Phenacyl deprotection": "6.2.6",
1529
+ "Aza-Henry reaction": "3.11.75",
1530
+ "1,3-Vinyl ether rearrangement": "3.11.192",
1531
+ "Carbonic anhydride + amine reaction": "2.1.43",
1532
+ "Allan-Robinson reaction": "4.2.55",
1533
+ "Chloro to nitro": "9.7.180",
1534
+ "Quinoline synthesis": "4.1.158",
1535
+ "Amide to aldehyde reduction": "7.9.74",
1536
+ "Acyl halide to aldehyde reduction": "7.9.32",
1537
+ "Phthalazinone synthesis": "4.1.75",
1538
+ "Carboxylic anhydride + imine reaction": "2.1.38",
1539
+ "Azoxy reduction": "7.9.50",
1540
+ "Mislow-Evans rearrangement": "1.7.66",
1541
+ "Sulfoxide alpha alkylation": "3.11.178",
1542
+ "Ketene + amine reaction": "2.1.63",
1543
+ "Aza Davis oxaziridine oxidation": "8.4.5",
1544
+ "Chloro to thiocyanato": "9.7.220",
1545
+ "Ketone Mozingo reduction": "7.9.18",
1546
+ "Alpha ketone oxidation": "8.8.38",
1547
+ "Ketone Hosomi-Sakurai reaction": "3.11.23",
1548
+ "Aldehyde allyl lithium addition": "3.9.145",
1549
+ "Dimethyl acetal reductive amination": "1.2.12",
1550
+ "Carboxylic anhydride + sulfinamide reaction": "2.1.13",
1551
+ "Bromopyridine to pyridone": "9.7.461",
1552
+ "[2,3]-Wittig rearrangement": "3.11.127",
1553
+ "Carbazole synthesis": "4.1.101",
1554
+ "Benzimidazolimine synthesis": "4.1.74",
1555
+ "Azo to hydrazo reduction": "7.9.69",
1556
+ "Azido sulfamate reaction": "9.7.512",
1557
+ "Copper catalyzed arylation": "3.9.134",
1558
+ "Deutero to bromo": "10.1.19",
1559
+ "Isothiocyanate + alcohol reaction": "2.4.3",
1560
+ "Mesyloxy Suzuki coupling": "3.1.9",
1561
+ "Amino to thiocyanato": "9.7.175",
1562
+ "Acyl halide Schmidt reaction": "9.7.309",
1563
+ "Meyer-Schuster rearrangement": "9.7.401",
1564
+ "1,3-Oxazine-2,4-dione synthesis": "4.2.48",
1565
+ "Oxa Wagner-Meerwein rearrangement": "3.11.182",
1566
+ "Aldehyde dioxane deprotection": "6.5.11",
1567
+ "Aldehyde dithiolane protection": "5.5.5",
1568
+ "Ketone dioxane deprotection": "6.5.4",
1569
+ "Aldehyde dithiolane deprotection": "6.5.5",
1570
+ "Pyrrolo[1,2-c]pyrimidine synthesis": "4.1.217",
1571
+ "Gatterman amide synthesis": "3.11.249",
1572
+ "2-Thioxopyrimidine-4,6-dione synthesis": "4.1.112",
1573
+ "Cadogan-Sundberg indole synthesis": "4.1.135",
1574
+ "Aldehyde Peterson olefination": "3.11.72",
1575
+ "Paal-Knorr thiophene synthesis": "4.3.2",
1576
+ "3-Thioxo-1,2,4-triazinane-5,6-dione synthesis": "4.1.265",
1577
+ "Chloro Negishi preparation": "9.7.38",
1578
+ "Dihydropyridine synthesis": "4.1.55",
1579
+ "Mesyloxy Kolbe isonitrile synthesis": "9.7.237",
1580
+ "Fluorosulfonyl to sulfonato": "9.7.362",
1581
+ "Isothiocyanato to thioureido": "9.7.300",
1582
+ "Selenazole synthesis": "4.4.2",
1583
+ "Thiohosphate ester synthesis": "1.9.26",
1584
+ "Thio sulfamate reaction": "9.7.514",
1585
+ "Oxirane O-elimination": "9.7.531",
1586
+ "Sugasawa reaction": "3.11.88",
1587
+ "1,3-dihydro-1,4-diazepine-2-one synthesis": "4.1.185",
1588
+ "Aminal deamination": "9.7.559",
1589
+ "Kroehnke pyridine synthesis": "4.1.51",
1590
+ "Naraska-Prasad reduction": "7.5.11",
1591
+ "1,2,3,4-tetrahydro-1,4-diazepine-5-one synthesis": "4.1.129",
1592
+ "Baeyer-Emmerling indole synthesis": "4.1.41",
1593
+ "1,3-Diol Grob fragmentation": "9.7.456",
1594
+ "Thioamide Schotten-Baumann": "2.1.8",
1595
+ "Sulfoxy to hydroxy": "9.7.126",
1596
+ "Bartoli indole synthesis": "4.1.124",
1597
+ "Charette asymmetric cyclopropanation": "3.9.102",
1598
+ "Cyanocarbonyl decarbonylation": "9.7.282",
1599
+ "Gomberg-Bachmann reaction": "3.9.63",
1600
+ "Diazoalkane amidation": "1.7.69",
1601
+ "Buchwald-Hartwig phosphination": "1.9.43",
1602
+ "Alkylsulfoxy N-arylation": "1.3.20",
1603
+ "Ketone Peterson olefination": "3.11.73",
1604
+ "O-MEM protection": "5.3.8",
1605
+ "Chlorosulfonyl to sulfonato": "9.7.361",
1606
+ "Nitro to oxime reduction": "7.9.71",
1607
+ "Sulfonate Corey-Seebach reaction": "3.9.168",
1608
+ "Carboxy to iodo": "9.7.193",
1609
+ "Oppenauer oxidation": "8.1.16",
1610
+ "Retro Aldol addition": "9.7.396",
1611
+ "Reppe carbonylation": "3.9.149",
1612
+ "Eschenmoser-Claisen rearrangement": "3.11.107",
1613
+ "Thorpe-Ziegler reaction": "3.11.230",
1614
+ "[1,2,3]Triazolo[1,5-a]pyridine_synthesis": "4.1.127",
1615
+ "Milas hydroxylation": "10.4.10",
1616
+ "Carbonate decarbonylation": "9.7.324",
1617
+ "Chugaev elimination": "9.5.3",
1618
+ "Davidson oxazole synthesis": "4.2.68",
1619
+ "Magnesium salt separation": "11.9.7",
1620
+ "Pyridone to iodopyridine": "9.1.13",
1621
+ "Wacker cyclization": "4.2.58",
1622
+ "Niementowski quinoline synthesis": "4.1.31",
1623
+ "Ketal Hosomi-Sakurai reaction": "3.11.22",
1624
+ "Arens-van Dorp synthesis": "3.9.93",
1625
+ "Benzofuroxan synthesis": "4.2.49",
1626
+ "Nitro to hydrazino": "9.7.91",
1627
+ "Grignard + acid anhydride ketone synthesis": "3.7.27",
1628
+ "Alkyne halide reaction": "3.9.125",
1629
+ "Peroxy to hydroxy": "7.9.43",
1630
+ "Epoxide + ammonia + aldehyde coupling": "1.2.34",
1631
+ "Sulfamate alpha alkylamination": "3.11.214",
1632
+ "Ester alkyl lithium addition": "3.9.123",
1633
+ "Shapiro reaction": "9.7.389",
1634
+ "Diazonio to fluoro": "9.7.121",
1635
+ "von Braun reaction": "9.7.307",
1636
+ "Olefin hydroalkylation": "3.11.74",
1637
+ "Palladium arylhalide acylation": "3.5.17",
1638
+ "Carbon dioxide + epoxide reaction": "2.4.21",
1639
+ "Trithiocarbonate hydrolysis": "9.7.554",
1640
+ "Phosphate ester cleavage": "9.7.544",
1641
+ "Clemmensen reduction": "7.9.3",
1642
+ "Ammonium ester synthesis": "2.6.31",
1643
+ "Aldehyde Leuckart reaction": "1.2.7",
1644
+ "Aza Danishefsky cycloaddition": "4.1.172",
1645
+ "Epoxide Hosomi-Sakurai reaction": "3.11.20",
1646
+ "Iodo to chlorosulfonyl": "9.7.251",
1647
+ "Disulfide to chlorosulfonyl": "9.7.229",
1648
+ "Base catalyzed gamma elimination": "9.7.596",
1649
+ "Reissert indole synthesis": "4.1.109",
1650
+ "Imide + ammonium reaction": "2.1.66",
1651
+ "Trihaloacetyl + amine reaction": "2.1.71",
1652
+ "Aza-Wittig reaction": "1.2.23",
1653
+ "Allyl ether pyrolysis": "9.7.520",
1654
+ "Enamine to alkene reduction": "7.9.61",
1655
+ "Emde degradation": "9.7.256",
1656
+ "Aryl to quinone oxidation": "8.8.37",
1657
+ "Hofmann isonitrile synthesis": "9.7.168",
1658
+ "Appel cyclization": "4.1.160",
1659
+ "Staudinger ligation": "2.1.75",
1660
+ "Wharton reaction": "7.9.82",
1661
+ "Carboxylic acid + amide reaction": "2.6.22",
1662
+ "Chichibabin amination": "1.3.11",
1663
+ "O-DMPM deprotection": "6.3.21",
1664
+ "Iodo Gabriel synthesis": "9.7.76",
1665
+ "Hydroxyalkene pyrolysis": "9.7.516",
1666
+ "N-Acyl thioamide Schotten-Baumann": "2.1.60",
1667
+ "Bromo Cristol-Firth-Hunsdiecker reaction": "9.7.422",
1668
+ "De Kimpe aziridine synthesis": "4.1.132",
1669
+ "Ferrier rearrangement": "1.7.46",
1670
+ "Mesyloxypyridine to pyridone": "9.7.568",
1671
+ "Protodeboronation": "9.7.443",
1672
+ "Oxidative haloalkane coupling": "3.11.218",
1673
+ "Pyridone Suzuki-type coupling": "3.1.14",
1674
+ "Formamido to isoselenocyanato": "9.7.316",
1675
+ "Carboxylic anhydride to peroxyacid": "9.7.295",
1676
+ "Nitrile + hydrazine reaction": "2.5.6",
1677
+ "Johnson-Claisen rearrangement": "3.11.109",
1678
+ "Hinsberg thiophene synthesis": "4.3.16",
1679
+ "Bromo Nierenstein reaction": "3.11.59",
1680
+ "Barbas-List reaction": "3.11.242",
1681
+ "Bromo Grignard carboxylation": "3.7.6",
1682
+ "1,5-Hydrogen migration": "9.7.478",
1683
+ "Tsuji-Trost reaction": "3.5.10",
1684
+ "Thiazole-2-thione synthesis": "4.3.31",
1685
+ "Overman rearrangement": "9.7.453",
1686
+ "Cyanohydrination hydrolysis": "9.7.497",
1687
+ "Swarts fluorination": "9.7.312",
1688
+ "Paterno-Buchi reaction": "4.2.43",
1689
+ "Jocic reaction": "9.7.588",
1690
+ "Fluorocarbonyl to carboxy": "9.7.246",
1691
+ "Overman reaction": "9.7.454",
1692
+ "Bernet-Vasella ring opening": "9.7.409",
1693
+ "Iodoform reaction": "9.7.243",
1694
+ "Oxa-di-pi-methane rearrangement": "3.11.185",
1695
+ "Fluoro to formyl": "9.7.144",
1696
+ "Acetal reductive amination": "1.2.40",
1697
+ "Silane chlorination": "10.1.29",
1698
+ "Balz-Schiemann reaction": "9.7.14",
1699
+ "Ketone Corey-Kim oxidation": "8.1.20",
1700
+ "Barton-Zard reaction": "4.1.153",
1701
+ "Oppenauer-Woodward oxidation": "8.1.17",
1702
+ "Ketone dehydration": "9.5.13",
1703
+ "Kabachnik-Fields reaction": "10.4.28",
1704
+ "Carbamimidothioate hydrolysis": "9.7.570",
1705
+ "Phosphoryl deoxygenation": "7.9.20",
1706
+ "N-Mtr deprotection": "6.1.38",
1707
+ "Koch-Haaf reaction": "3.11.226",
1708
+ "Radical cyclization": "3.11.223",
1709
+ "Semi-pinacol rearrangement": "9.7.405",
1710
+ "Banert cascade": "4.1.250",
1711
+ "Ketal reductive diamination": "1.2.35",
1712
+ "Stork-Zhao-Wittig olefination": "3.8.3",
1713
+ "Nitrate ester oxidation": "8.4.6",
1714
+ "Blaise ketone synthesis": "3.9.61",
1715
+ "Alkene desilylation": "6.5.14",
1716
+ "Aryl thioether synthesis": "1.8.19",
1717
+ "Calcium salt separation": "11.9.5",
1718
+ "Katritzky pyrylium-pyridinium method": "4.1.143",
1719
+ "Willgerodt-Kindler reaction": "2.1.36",
1720
+ "Povarov reaction": "4.1.239",
1721
+ "Trihaloacetamide + amine reaction": "2.3.19",
1722
+ "Heck-Matsuda reaction": "3.2.11",
1723
+ "Iodo to hydrazino": "9.7.118",
1724
+ "Pyrimidin-2-one synthesis": "4.1.62",
1725
+ "Electrocyclic ring opening": "9.7.449",
1726
+ "Chloro to sulfo": "9.7.172",
1727
+ "Fluorosulfonyl to sulfo": "9.7.131",
1728
+ "Alkyne desilylation": "6.5.15",
1729
+ "1,2,5-Selenadiazole synthesis": "4.4.9",
1730
+ "Wurtz coupling": "3.11.15",
1731
+ "Trihaloacetamide + alcohol reaction": "2.4.18",
1732
+ "Dreiding-Schmidt reaction": "4.2.70",
1733
+ "Dihydropyrazolo[3,4-d]pyrimidin-4-one synthesis": "4.1.208",
1734
+ "Isocyanato to ureido": "9.7.299",
1735
+ "1,2,4-Thiadiazolidine-3,5-dione synthesis": "4.3.35",
1736
+ "Indazolone synthesis": "4.1.43",
1737
+ "Imidic acid + amine condensation": "2.5.1",
1738
+ "Bromo selenoether synthesis": "1.9.14",
1739
+ "Perkow reaction": "1.7.10",
1740
+ "Bromo Gabriel synthesis": "9.7.18",
1741
+ "Cyanate urea synthesis": "2.3.23",
1742
+ "Triflyloxy Heck-type reaction": "3.2.8",
1743
+ "Cyano to aminoamidino": "9.7.301",
1744
+ "Oxime to aziridine reduction": "4.1.197",
1745
+ "Phthalazine synthesis": "4.1.77",
1746
+ "Carreira alkynylation": "3.9.101",
1747
+ "Haworth reaction": "3.10.11",
1748
+ "[1,2,4]Triazolo[4,3-b]triazin-7-one synthesis": "4.1.252",
1749
+ "[1,2,4]Triazolo[4,3-a]pyridin-3-thione synthesis": "4.1.207",
1750
+ "Bromocarbonyl to carboxy": "9.7.244",
1751
+ "Aluminium conjugate addition": "3.9.141",
1752
+ "CO2H-THP deprotection": "6.2.9",
1753
+ "Wenker synthesis": "4.1.66",
1754
+ "Chlorosulfonyl to sulfino": "9.7.111",
1755
+ "Hass-Bender oxidation": "8.6.12",
1756
+ "Nenitzescu indole synthesis": "4.1.110",
1757
+ "Ozone 1,3-cycloaddition": "4.2.90",
1758
+ "Staudinger reaction": "1.9.44",
1759
+ "Gassman indolone synthesis": "4.1.36",
1760
+ "Reissert reaction": "3.11.71",
1761
+ "Iodo formaldehyde Barbier reaction": "3.9.31",
1762
+ "Hay reaction": "3.9.135",
1763
+ "Aziridine + thiol coupling": "1.8.9",
1764
+ "Isocyanato to isocyano reduction": "7.9.58",
1765
+ "Bromo to isocyano": "9.7.151",
1766
+ "Helferich method": "1.7.54",
1767
+ "Aldehyde autoxidation": "8.8.15",
1768
+ "Iodo cyclopropyl ring opening": "10.1.40",
1769
+ "Danishefsky cycloaddition": "3.11.149",
1770
+ "Allyl alcohol oxidation": "8.1.34",
1771
+ "3,5-Dihydroimidazol-4-one synthesis": "4.1.212",
1772
+ "2,3-Dihydro-1,3-benzoxazole synthesis": "4.2.108",
1773
+ "Carbon dioxide + amine + halide reaction": "2.3.20",
1774
+ "Chloro Nierenstein reaction": "3.11.60",
1775
+ "Gewald furan synthesis": "4.2.10",
1776
+ "Alkene sulfoxy addition": "10.3.3",
1777
+ "Sulfone to sulfonamide": "9.7.553",
1778
+ "Keto hydrosilylation": "9.7.397",
1779
+ "Gattermann-Koch formylation": "3.9.57",
1780
+ "Petrenko-Kritschenko piperidone synthesis": "4.1.199",
1781
+ "Nitro to formamido": "2.1.35",
1782
+ "Thiazol-4-one synthesis": "4.3.21",
1783
+ "Nitrate ester hydrolysis": "9.7.412",
1784
+ "Bismuth N-arylation": "1.3.29",
1785
+ "Dithiane to difluoro": "9.7.235",
1786
+ "O-Bucherer reaction": "9.7.415",
1787
+ "Thioic acid to thioyl chloride": "9.7.346",
1788
+ "Zweifel olefination": "3.11.124",
1789
+ "Eastwood reaction": "9.7.399",
1790
+ "Pyrazoline synthesis": "4.1.202",
1791
+ "Semmler-Wolff reaction": "9.5.2",
1792
+ "Marko-Lam deoxygenation": "7.9.86",
1793
+ "Hydrazone to cyano": "9.7.525",
1794
+ "Oxaziridine synthesis": "4.2.69",
1795
+ "Keto ylid pyrolysis": "9.7.543",
1796
+ "Boyer reaction": "2.1.22",
1797
+ "Chapman rearrangement": "1.3.24",
1798
+ "Electrocyclic ring closure": "3.11.165",
1799
+ "Mukaiyama-Hoshino method": "9.7.400",
1800
+ "Iodo to thiocyanato": "9.7.222",
1801
+ "Ketone Darzens reaction": "4.2.34",
1802
+ "Ireland-Claisen rearrangement": "3.11.108",
1803
+ "Modified Julia olefination": "3.9.46",
1804
+ "N-Oxide acylation": "1.7.74",
1805
+ "Pschorr cyclization": "3.9.62",
1806
+ "Abramov reaction": "1.9.10",
1807
+ "Baker-Venkataraman rearrangement": "3.11.97",
1808
+ "Wagner-Meerwein elimination": "3.11.173",
1809
+ "Ketone + hydroxylamine reaction": "1.9.49",
1810
+ "Cadogan coupling": "3.11.123",
1811
+ "Alkyne sulfamate reaction": "3.11.216",
1812
+ "Iodo Nozaki-Hiyama-Kishi reaction": "3.9.10",
1813
+ "1,3-Benzothiazin-4-one synthesis": "4.3.10",
1814
+ "Passerini reaction": "2.1.29",
1815
+ "Corey-Fuchs reaction": "9.7.53",
1816
+ "Aza-Wacker cyclization": "4.1.149",
1817
+ "Aromatic Menshutkin reaction": "1.3.21",
1818
+ "Atherton-Todd reaction": "9.7.292",
1819
+ "Bohlmann-Rahtz pyridine synthesis": "4.1.133",
1820
+ "Mukaiyama hydration": "10.4.31",
1821
+ "Sulfonic ester oxidation": "8.2.6",
1822
+ "Jacobsen epoxidation": "4.2.36",
1823
+ "Trichloroalkyl to acid chloride": "9.7.549",
1824
+ "Smiles rearrangement": "9.7.581",
1825
+ "Evans-Saksena reduction": "7.5.6",
1826
+ "Aliphatic diazonium coupling": "1.2.39",
1827
+ "Liebeskind-Sonogashira coupling": "3.5.13",
1828
+ "[1,2,4]Triazolo[4,3-a]pyridin-3-one synthesis": "4.1.84",
1829
+ "Ketone Corey-Seebach reaction": "3.9.74",
1830
+ "Isothiazol-3-one synthesis": "4.3.38",
1831
+ "Crossed Cannizzaro reaction": "7.9.21",
1832
+ "Hydroxy to peroxy": "8.8.28",
1833
+ "CO2H-MOM deprotection": "6.2.8",
1834
+ "Silane alkylation": "1.9.41",
1835
+ "Alkene hydroboration": "10.4.4",
1836
+ "Combes quinoline synthesis": "4.1.26",
1837
+ "Thiirane reduction": "7.9.77",
1838
+ "Strecker degradation": "9.7.580",
1839
+ "1,2,4-Triazine-3,5-dione synthesis": "4.1.264",
1840
+ "N-Oxide alkylation": "1.7.57",
1841
+ "Epoxide + halogen reaction": "9.7.440",
1842
+ "N-Bucherer reaction": "9.7.416",
1843
+ "P-hydroxylation": "8.8.27",
1844
+ "Enol-keto tautomerisation": "11.11.2",
1845
+ "Kulinkovich-de Meijere reaction": "3.9.66",
1846
+ "Cyclobutane 2 + 2 ring expansion": "3.11.170",
1847
+ "Sulfur chlorination": "10.1.15",
1848
+ "Thiophene desulfurization": "9.7.504",
1849
+ "Hantzsch pyrrole synthesis": "4.1.147",
1850
+ "Hydroquinazolinone synthesis": "4.1.44",
1851
+ "Pictet-Spengler cyclization": "4.1.17",
1852
+ "Iodopyridine to pyridone": "9.7.564",
1853
+ "1,2,4-Thiadiazol-5-one synthesis": "4.3.37",
1854
+ "Thioester aminolysis": "9.7.550",
1855
+ "Kolbe electrolysis": "3.11.104",
1856
+ "Oxo to selenoxo": "9.7.273",
1857
+ "Atherton-Todd coupling": "2.8.7",
1858
+ "Cyano sulfamate reaction": "3.11.215",
1859
+ "Dondoni homologation": "3.11.154",
1860
+ "Alkylborane disulfide coupling": "1.8.35",
1861
+ "Aza Norrish-Yang cyclization": "3.11.222",
1862
+ "Iodo Grignard preparation": "9.7.77",
1863
+ "Glaser coupling": "3.9.20",
1864
+ "Alkyne metathesis": "3.9.92",
1865
+ "Hydroxy to boronooxy": "9.7.323",
1866
+ "Thioester hydrolysis": "9.7.350",
1867
+ "Diels-Reese reaction": "4.1.249",
1868
+ "Grignard ketal reaction": "3.7.25",
1869
+ "Alpha hydroxy imine rearrangement": "9.7.490",
1870
+ "Pyridone Suzuki coupling": "3.1.13",
1871
+ "Fluoro Hunsdiecker reaction": "9.7.202",
1872
+ "Kazmaier-Claisen rearrangement": "3.9.126",
1873
+ "Borane to hydroxy": "9.7.483",
1874
+ "Zincke disulfide cleavage": "9.7.228",
1875
+ "1,2-Hydrovinylation": "3.9.86",
1876
+ "Silane decarbonation": "9.7.459",
1877
+ "Alkene Ritter reaction": "2.1.20",
1878
+ "N-Nitroso reduction": "7.9.70",
1879
+ "Silane fluorination": "10.1.31",
1880
+ "Carboxylic ester + sulfinamide reaction": "2.1.16",
1881
+ "Fluoro Kolbe nitrile synthesis": "9.7.159",
1882
+ "Beckmann fragmentation": "9.7.392",
1883
+ "Enamine-imine tautomerisation": "11.11.4",
1884
+ "Widman-Stoermer synthesis": "4.1.234",
1885
+ "Imidazole N-oxide synthesis": "4.1.261",
1886
+ "Aldehyde Schmidt reaction": "9.7.271",
1887
+ "Blum-Ittah aziridine synthesis": "4.1.168",
1888
+ "Thiourea to carbdiimide": "9.7.522",
1889
+ "1,3-Dihydroimidazol-2-one synthesis": "4.1.186",
1890
+ "Fiesselmann thiophene synthesis": "4.3.25",
1891
+ "1,2-Migratory nucleophilic substitution": "9.7.485",
1892
+ "Burgess alcohol dehydration": "9.5.8",
1893
+ "Hydrazo reduction": "7.9.51",
1894
+ "Thiodiazene synthesis": "9.7.468",
1895
+ "Phosphorus chlorination": "10.1.28",
1896
+ "Ketene hydrolysis": "9.7.363",
1897
+ "Nitrogen iodination": "10.1.34",
1898
+ "Sulfone extrusion": "9.7.510",
1899
+ "Bromo to chloro Negishi preparation": "9.7.297",
1900
+ "Imidazo[1,5-a]pyrimidine synthesis": "4.1.260",
1901
+ "Crabbe homologation": "3.9.7",
1902
+ "O-Nosyl deprotection": "6.3.12",
1903
+ "Catalytic keto reductive coupling": "3.9.137",
1904
+ "Thiophosphate ester hydrolysis": "9.7.359",
1905
+ "Grignard isothiocyanate reaction": "3.7.22",
1906
+ "Diazonio to bromo": "9.7.119",
1907
+ "Zweifel alkynylation": "3.11.125",
1908
+ "Silane bromination": "10.1.30",
1909
+ "Epoxide to alpha siloxy azido": "9.7.495",
1910
+ "Sulfone elimination": "9.7.533",
1911
+ "Hydroxy to nitrosooxy": "9.7.216",
1912
+ "Ichikawa rearrangement": "1.4.2",
1913
+ "Silanol to silyl fluoride": "9.7.341",
1914
+ "Elbs persulfate oxidation": "8.8.12",
1915
+ "Selenoxide cleavage": "9.7.541",
1916
+ "Chloro selenoether synthesis": "1.9.15",
1917
+ "Alkene hydroxyiodination": "10.1.27",
1918
+ "Heck oxyarylation": "3.2.9",
1919
+ "2,3-dihydro-1,4-diazepine-2-one 4-oxide synthesis": "4.1.266",
1920
+ "5-Oxazolone synthesis": "4.2.86",
1921
+ "Gewald pyrrole synthesis": "4.1.38",
1922
+ "1,2-Dithiolane synthesis": "4.3.17",
1923
+ "Retro-Henry reaction": "8.1.27",
1924
+ "Chloro Takai olefination": "3.9.49",
1925
+ "Darzens-Nenitzescu acylation": "3.10.8",
1926
+ "Bergmann amino acid synthesis": "3.11.28",
1927
+ "Hell-Volhard-Zelinsky halogenation": "10.1.14",
1928
+ "1,5-Alkyl migration": "3.11.194",
1929
+ "Fetizon ketone oxidation": "8.1.42",
1930
+ "Aryl selenoether synthesis": "1.9.19",
1931
+ "Hayashi rearrangement": "9.7.590",
1932
+ "Brown alkyne zipper reaction": "9.7.414",
1933
+ "Grignard isocyanate reaction": "3.7.21",
1934
+ "Birch alkylation": "3.9.33",
1935
+ "Tiffeneau-Demjanov rearrangement": "3.11.77",
1936
+ "Benzilic acid rearrangement": "9.7.382",
1937
+ "Adamczyk-Netzel protocol": "9.7.607",
1938
+ "Rupe rearrangement": "9.7.402",
1939
+ "Aniline Teuber reaction": "8.4.7",
1940
+ "Nitro Hunsdiecker reaction": "9.7.506",
1941
+ "N-Desilylation": "9.7.603",
1942
+ "Alpha halo ether + amine reaction": "2.1.67",
1943
+ "Nitro to cyano": "9.7.523",
1944
+ "Phosphonous ester synthesis": "1.7.60",
1945
+ "Dowd-Beckwith ring expansion": "3.9.106",
1946
+ "Boyland-Sims oxidation": "8.8.13",
1947
+ "Amide Ireland-Claisen rearrangement": "3.11.183",
1948
+ "Nitro O,C-migration": "9.7.602",
1949
+ "Alkylperoxy to keto": "8.8.36",
1950
+ "Zinner hydroxylamine synthesis": "9.7.308",
1951
+ "Amide alkyl lithium addition": "3.9.163",
1952
+ "Amino Sommelet reaction": "9.7.364",
1953
+ "Chloro Corey-Seebach reaction": "3.9.70",
1954
+ "Reilly-Hickinbottom rearrangement": "3.9.150",
1955
+ "Imino to thioxo": "9.7.605",
1956
+ "Fluoro Gabriel synthesis": "9.7.62",
1957
+ "Teuber reaction": "8.1.48",
1958
+ "Chloroformamide dehydrochlorination": "9.7.509",
1959
+ "Stille reaction": "3.4.1",
1960
+ "Aldehyde decarbonylation": "9.7.536",
1961
+ "Aminopyridine to thiopyridone": "9.7.576",
1962
+ "Phenol imination": "1.9.25",
1963
+ "Bernthsen thionation": "4.3.24",
1964
+ "Simonis chromone cyclization": "4.2.38",
1965
+ "Peroxy ester synthesis": "1.7.55",
1966
+ "Fujiwara lanthanide reaction": "3.9.118",
1967
+ "Phosphoramidite synthesis": "1.9.36",
1968
+ "Thioic acid alkene synthesis": "1.7.23",
1969
+ "Thioic acid to thioamide": "9.7.348",
1970
+ "Epoxide Corey-Seebach reaction": "3.9.71",
1971
+ "Thiirane + hydroxy coupling": "1.7.67",
1972
+ "Reductive ring contraction": "4.1.81",
1973
+ "Pudovik reaction": "10.4.29",
1974
+ "Nitroso to nitro": "8.4.12",
1975
+ "Pyrrolidine-2,4-dione synthesis": "4.1.190",
1976
+ "Thia vinylcyclopropane rearrangement": "4.3.28",
1977
+ "Alpha aldehyde rearrangement": "9.7.489",
1978
+ "Aldehyde Sarett oxidation": "8.1.12",
1979
+ "Pfitzner-Moffatt ketone oxidation": "8.1.38",
1980
+ "Chloro Grignard carboxylation": "3.7.7",
1981
+ "Mesyloxy Suzuki-type coupling": "3.1.11",
1982
+ "[1,2,4]Triazolo[3,4-f]triazin-8-one synthesis": "4.1.253",
1983
+ "Aromatic peroxide alkylation": "3.11.205",
1984
+ "Oxy-Cope rearrangement": "3.11.65",
1985
+ "Bromo Nozaki-Hiyama-Kishi reaction": "3.9.8",
1986
+ "1,3-Alkyl migration": "3.11.193",
1987
+ "Iodo Kochi reaction": "9.7.199",
1988
+ "Thiocarbonyl ylide 1,3-cycloaddition": "4.3.39",
1989
+ "Sulfenate ester synthesis": "1.9.33",
1990
+ "Dediazoniation": "7.9.59",
1991
+ "Griesbaum coozonolysis": "4.2.91",
1992
+ "Cope rearrangement": "3.11.64",
1993
+ "Alkoxyallene hydrolysis": "9.7.491",
1994
+ "Boger cyclopropane synthesis": "3.11.132",
1995
+ "Sulfonamide to sulfonyl hydrazide": "9.7.469",
1996
+ "Aryl sulfonamidation": "1.3.27",
1997
+ "Hiyama-Denmark coupling": "3.5.6",
1998
+ "Azoxy to azo reduction": "7.9.55",
1999
+ "Thionoester + amine reaction": "2.8.9",
2000
+ "Edman degradation": "9.7.426",
2001
+ "Imidazo[1,2-a]pyridin-5-one synthesis": "4.1.205",
2002
+ "Diazonio to chloro": "9.7.120",
2003
+ "Eschenmoser sulfide contraction": "3.11.157",
2004
+ "Pyran-2-one synthesis": "4.2.53",
2005
+ "Bromo Kolbe isonitrile synthesis": "9.7.156",
2006
+ "Diazonio to hydrazino reduction": "7.9.7",
2007
+ "Fluoro Corey-Seebach reaction": "3.9.72",
2008
+ "Halophosphate hydrolysis": "9.7.599",
2009
+ "Diarylketone decarbonylation": "9.7.501",
2010
+ "Bobbitt reaction": "4.1.198",
2011
+ "1,2,4-Triazine-1,4-dioxide synthesis": "4.1.221",
2012
+ "Mann ether demethylation": "6.3.14",
2013
+ "Imidazo[1,5-a][1,3,5]triazin-4-one synthesis": "4.1.230",
2014
+ "Doebner reaction": "4.1.28",
2015
+ "Carbon dioxide + alcohol + halide reaction": "2.4.19",
2016
+ "Alpha chloroamine dehydrochlorination": "9.7.557",
2017
+ "Darzens tetralin synthesis": "3.11.62",
2018
+ "Azide elimination": "9.7.494",
2019
+ "Acyl halide to ketene": "9.7.538",
2020
+ "Conjugate cyclization": "3.9.84",
2021
+ "Isonitrile to carbamate": "9.7.556",
2022
+ "1,3-Aryl migration": "3.11.197",
2023
+ "Diselenide reduction": "7.9.26",
2024
+ "Piloty-Robinson synthesis": "4.1.104",
2025
+ "Wohl-Aue reaction": "4.1.233",
2026
+ "1,2,4-Thiadiazol-3-one synthesis": "4.3.36",
2027
+ "Weinreb chloro coupling": "3.9.15",
2028
+ "Diazonio to azido": "9.7.274",
2029
+ "Diazonio to iodo": "9.7.122",
2030
+ "Pyridone to fluoropyridine": "9.1.12",
2031
+ "Carbonyl extrusion": "9.7.518",
2032
+ "Claisen rearrangement": "3.11.68",
2033
+ "Chlorocarbonyl decarbonylation": "9.7.281",
2034
+ "Mallory reaction": "3.11.238",
2035
+ "Nitrone 1,3-cycloaddition": "4.2.92",
2036
+ "Stille carbonylative coupling": "3.4.11",
2037
+ "Di-pi-methane rearrangement": "3.11.152",
2038
+ "Stobbe condensation": "3.11.40",
2039
+ "Diketene + hydroxylamine reaction": "2.6.25",
2040
+ "Dakin-West reaction": "3.11.112",
2041
+ "Nitrous oxide 1,3-cycloaddition": "4.2.93",
2042
+ "Boronic acid coupling": "3.9.81",
2043
+ "Silylketone alkyl lithium addition": "3.9.164",
2044
+ "Benzoin condensation": "3.11.105",
2045
+ "2-Thioxoimidazolidine-4,5-dione synthesis": "4.1.210",
2046
+ "Diselenide cleavage": "9.7.313",
2047
+ "Selenazolidin-4-one synthesis": "4.4.3",
2048
+ "Lossen rearrangement": "9.7.189",
2049
+ "1,2,4-Triazin-6-one synthesis": "4.1.219",
2050
+ "Reissert hydrolysis": "9.7.272",
2051
+ "Pyrazolo[1,5-d][1,2,4]triazine synthesis": "4.1.220",
2052
+ "Cesium salt separation": "11.9.6",
2053
+ "Hydroperoxide synthesis": "8.6.8",
2054
+ "Alkane coupling": "3.11.209",
2055
+ "Dutt-Wormall reaction": "9.7.425",
2056
+ "Epoxide to alkane reduction": "7.9.80",
2057
+ "Ultee cyanohydrin method": "9.7.263",
2058
+ "Imidazo[1,2-a]pyrimidin-5-one synthesis": "4.1.184",
2059
+ "Kroehnke aldehyde synthesis": "8.1.49",
2060
+ "Boennemann cyclization": "4.1.52",
2061
+ "Stephen aldehyde synthesis": "9.7.270",
2062
+ "Chloro alkoxylation": "1.7.61",
2063
+ "Carboxylic anhydride + amine to imino ester": "2.8.8",
2064
+ "Phosphoramide synthesis": "1.9.31",
2065
+ "Amino to diazo": "9.7.439",
2066
+ "Oxidative decyanation": "9.7.547",
2067
+ "Kowalski ester homologation": "3.9.153",
2068
+ "Myers deoxygenation": "7.9.84",
2069
+ "Fluoro Grignard + nitrile ketone synthesis": "3.7.12",
2070
+ "Oxime-nitroso tautomerisation": "11.11.6",
2071
+ "Nitrogen fluorination": "10.1.35",
2072
+ "Achmatowicz reaction": "4.2.46",
2073
+ "Aldehyde Nef synthesis": "3.9.39",
2074
+ "Nitro to azoxy reductive coupling": "7.9.48",
2075
+ "Grignard + nitrile ketone synthesis": "3.7.18",
2076
+ "Fukuyama coupling": "3.5.5",
2077
+ "Borane coupling": "3.9.133",
2078
+ "Bromo to selanyl": "9.7.314",
2079
+ "Benkeser reduction": "7.9.78",
2080
+ "1,4-Hydrovinylation": "3.9.87",
2081
+ "Baer-Fischer amino sugar synthesis": "4.2.62",
2082
+ "Alkyne coupling": "3.9.21",
2083
+ "Sandmeyer triazene reacation": "1.3.34",
2084
+ "Isoselenocyanato to selenoureido": "9.7.318",
2085
+ "Thioalkylation": "3.11.180",
2086
+ "Iodo Takai-Utimoto olefination": "3.9.53",
2087
+ "Bromopyridine to thiopyridone": "9.7.571",
2088
+ "Wallach degradation": "3.11.30",
2089
+ "Carboxylic acid + sulfinamide condensation": "2.1.4",
2090
+ "Triflyloxy to nitro": "9.7.354",
2091
+ "Barton-Kellogg olefination": "3.11.50",
2092
+ "Adams decarboxylation": "9.7.594",
2093
+ "Chlorosulfinyl to sulfinamoyl": "9.7.50",
2094
+ "Baeyer diaryl methane synthesis": "3.10.6",
2095
+ "Diketone decarbonylation": "9.7.283",
2096
+ "Sulfinic acid + amine reaction": "2.2.2",
2097
+ "Carbdiimide hydrogenation": "7.9.44",
2098
+ "Boronooxy Stille reaction": "3.4.10",
2099
+ "[1,2,4]Triazolo[4,3-a]pyrazin-8-one synthesis": "4.1.206",
2100
+ "Castro-Stephens coupling": "3.9.38",
2101
+ "Hurd-Mori reaction": "4.3.43",
2102
+ "Silyl enol ether coupling": "3.9.139",
2103
+ "Orru imidazoline synthesis": "4.1.88",
2104
+ "Seyferth-Gilbert-Bestmann ketone homologation": "3.11.8",
2105
+ "Keck asymmetric allylation": "3.9.155",
2106
+ "Acid to peroxyacid": "9.7.294",
2107
+ "Phosphatoxy Stille reaction": "3.4.9",
2108
+ "Ehrlich-Sachs reaction": "1.9.28",
2109
+ "Furan oxidative cleavage": "8.8.43",
2110
+ "Thiirane S-elimination": "9.7.532",
2111
+ "Ciamician coupling": "3.11.144",
2112
+ "N-TES deprotection": "6.1.37",
2113
+ "Deutero to chloro": "10.1.20",
2114
+ "Thiele reaction": "2.6.32",
2115
+ "Alkylsulfonyl N-alkylation": "1.1.23",
2116
+ "Sandmeyer hydroxylation": "9.7.376",
2117
+ "Vinyl acetal rearrangement": "9.7.455",
2118
+ "Chloro Nozaki-Hiyama-Kishi reaction": "3.9.9",
2119
+ "[1,2,4]Triazolo[1,5-a]pyrimidin-5-one synthesis": "4.1.156",
2120
+ "Hantzsch pyridine synthesis": "4.1.146",
2121
+ "Aryl thiourea coupling": "1.8.24",
2122
+ "Bodroux reaction": "2.1.49",
2123
+ "Thioic acid to thioyl azide": "9.7.349",
2124
+ "Oxa Alder-Ene reaction": "1.7.44",
2125
+ "Aromatic peroxide arylation": "3.11.206",
2126
+ "Seyferth-Gilbert ketone homologation": "3.11.9",
2127
+ "Rosenmund reduction": "7.9.31",
2128
+ "Buchner ring expansion": "3.9.58",
2129
+ "Timmis reaction": "4.1.243",
2130
+ "Smith indole synthesis": "4.1.123",
2131
+ "Epoxyketone-furan rearrangement": "4.2.77",
2132
+ "Chloro formaldehyde Barbier reaction": "3.9.30",
2133
+ "Koch reaction": "3.11.49",
2134
+ "Corey-House synthesis": "3.9.75",
2135
+ "Volhard-Erdmann cyclization": "4.3.42",
2136
+ "Bernthsen acridine synthesis": "4.1.151",
2137
+ "Fetizon aldehyde oxidation": "8.1.41",
2138
+ "Perkin rearrangement": "4.2.102",
2139
+ "Cloke-Wilson rearrangement": "3.11.148",
2140
+ "McFadyen-Stevens reduction": "7.9.73",
2141
+ "Alkyne to alkane chlorination": "10.1.12",
2142
+ "Azomethine imine 1,3-cycloaddition": "4.1.232",
2143
+ "Fukuyama indole synthesis": "4.1.82",
2144
+ "Nitrogen hydrogenation": "7.9.10",
2145
+ "1,3-Hydroxy inorganic ester Grob fragmentation": "9.7.457",
2146
+ "Fluoro to oxo oxidation": "8.1.22",
2147
+ "Hydroxylamino to hydrazino": "9.7.465",
2148
+ "Ferrario-Ackermann thiocyclization": "1.8.22",
2149
+ "Zincke sulfur chlorination": "10.1.16",
2150
+ "Carboxylic acid + imidoyl chloride": "2.1.65",
2151
+ "Aziridine N-elimination": "9.7.530",
2152
+ "Alkylborane carbonylation": "3.11.201",
2153
+ "Cannizzaro reaction": "7.9.89",
2154
+ "Dihydropyrimidine-2,4-dione synthesis": "4.1.189",
2155
+ "Reed reaction": "10.3.5",
2156
+ "Zincke sulfur bromination": "10.1.18",
2157
+ "Keto aziridine rearrangement": "4.2.81",
2158
+ "N-Nitroso elimination": "9.7.513",
2159
+ "Chloro to selanyl": "9.7.315",
2160
+ "Peroxidation": "8.6.7",
2161
+ "Evans-Tishchenko reaction": "7.5.7",
2162
+ "Aldehyde Corey-Kim oxidation": "8.1.19",
2163
+ "Fluoro Nierenstein reaction": "3.11.61",
2164
+ "1,3,2-Diazastibole synthesis": "4.4.5",
2165
+ "1,3,2-Diazabismole synthesis": "4.4.6",
2166
+ "Imidazolone synthesis": "4.1.155",
2167
+ "David-Mukaiyama-Ueno oxidation": "8.1.46",
2168
+ "Benzidine rearrangement": "9.7.379",
2169
+ "Ruff-Fenton degradation": "8.1.51",
2170
+ "Chlorosulfonyl to chloro": "9.7.108",
2171
+ "Hydroxylamine oxidation": "8.4.16",
2172
+ "Alkyl sulfoxidation": "1.8.28",
2173
+ "Chlorocarbonyl Tsuji-Wilkinson decarbonylation": "9.7.276",
2174
+ "Berchtold enamine homologation": "3.11.141",
2175
+ "Sulfoxide extrusion": "9.7.451",
2176
+ "1,2,5-Thiadiazole synthesis": "4.3.32",
2177
+ "Vinylcyclopropane rearrangement": "3.11.169",
2178
+ "Acid chloride to peroxyacid": "9.7.296",
2179
+ "Aza vinylcyclopropane rearrangement": "4.1.180",
2180
+ "Chlorosulfenation": "10.4.26",
2181
+ "Thioamide reduction": "7.9.52",
2182
+ "Nitro to azo reductive coupling": "7.9.47",
2183
+ "Ammoxidation": "8.6.5",
2184
+ "Triazene synthesis": "1.3.22",
2185
+ "Barton deamination": "7.9.35",
2186
+ "Isocyano to methylamino reduction": "7.9.72",
2187
+ "Nitroso-oxime tautomerisation": "11.11.5",
2188
+ "Doyle-Kirmse reaction": "3.9.158",
2189
+ "Meisenheimer rearrangement": "1.7.15",
2190
+ "Iodo Cristol-Firth-Hunsdiecker reaction": "9.7.423",
2191
+ "Sandmeyer cyanation": "9.7.325",
2192
+ "Pyrimidine-2-thione synthesis": "4.1.263",
2193
+ "Woodward cis-hydroxylation": "10.4.13",
2194
+ "Jocic thioether reaction": "1.8.38",
2195
+ "Fenton glycol oxidation": "8.1.39",
2196
+ "Sulfate ester cleavage": "9.7.546",
2197
+ "Pfitzinger-Halberkann reaction": "4.1.228",
2198
+ "Chloro Kochi reaction": "9.7.197",
2199
+ "Martinet dioxindole synthesis": "4.1.138",
2200
+ "Alkene hydroxychlorination": "10.1.26",
2201
+ "Thia-Ferrier rearrangement": "1.8.23",
2202
+ "Graham reaction": "4.1.257",
2203
+ "Purin-6-one synthesis": "4.1.254",
2204
+ "Etard reaction": "8.6.9",
2205
+ "S-Acm deprotection": "6.4.5",
2206
+ "Trofimov reaction": "4.1.255",
2207
+ "Kharasch-Sosnovsky reaction": "8.6.3",
2208
+ "Bromocarbonyl decarbonylation": "9.7.280",
2209
+ "Thia-Bargellini reaction": "3.11.140",
2210
+ "Carbon dioxide alcoholysis": "2.4.20",
2211
+ "Silyl ether to alkoxide": "9.7.597",
2212
+ "Strontium salt separation": "11.9.8",
2213
+ "Pyridone to mesyloxypyridine": "9.7.567",
2214
+ "Grignard carbondisulfide reaction": "3.7.23",
2215
+ "Epoxide ring expansion": "4.2.75",
2216
+ "Iodo Hunsdiecker reaction": "9.7.203",
2217
+ "Ugi-Diels-Alder reaction": "4.1.238",
2218
+ "Brook rearrangement": "9.7.384",
2219
+ "Iminecyclopropane rearrangement": "4.1.192",
2220
+ "Cyclobutane ring expansion": "3.11.175",
2221
+ "Iodo to isocyano": "9.7.154",
2222
+ "Zimmermann addition": "3.11.115",
2223
+ "Pyrrolo[3,2-d]pyrimidine-2,4-dione synthesis": "4.1.131",
2224
+ "Barbier-Wieland degradation": "9.7.407",
2225
+ "1,2,4-Oxadiazol-5-thione synthesis": "4.2.88",
2226
+ "MNNG diazomethane preparation": "12.2",
2227
+ "Gattermann formylation": "3.9.56",
2228
+ "Liebeskind-Kumada coupling": "3.5.12",
2229
+ "Acyl-Claisen rearrangement": "3.11.147"
2230
+ }