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qa_id string | question string | answer string | level string | subtype string | source_medium_qa_id string | record_json string |
|---|---|---|---|---|---|---|
medium_convergence_00001 | BHLHE22 and RBCK1 have overlapping extended protein-interaction neighborhoods containing several shared proteins. Evidence concerning one of these shared proteins describes a RING finger protein functioning as an E3 ligase for oxidized iron regulatory protein suggesting oxidation signals ubiquitination. For which disea... | alpha 1-antitrypsin deficiency | Medium | convergence | {"qa_id":"medium_convergence_00001","source_qa_id":"medium_convergence_two_branch_unequal_context_0316","difficulty":"medium","subtype":"convergence","detailed_subtype":"two_branch_unequal_context","locator":"context","question":"BHLHE22 and RBCK1 have overlapping extended protein-interaction neighborhoods containing s... | |
medium_convergence_00002 | CENPW and CCND1 share more than one reported protein partner. Evidence concerning one of these shared proteins describes phosphorylated cyclin D1 recognition by a ubiquitin ligase where FBX4 and alphaB crystallin govern substrate specificity. For which disease is this protein reported as a biomarker? | malignant pleural mesothelioma | Medium | convergence | {"qa_id":"medium_convergence_00002","source_qa_id":"medium_convergence_two_branch_equal_context_0783","difficulty":"medium","subtype":"convergence","detailed_subtype":"two_branch_equal_context","locator":"context","question":"CENPW and CCND1 share more than one reported protein partner. Evidence concerning one of these... | |
medium_convergence_00003 | AKAP8L, LMNA, and TOPBP1 share more than one reported protein partner. Evidence concerning one of these shared proteins describes the physical interaction between a nuclear matrix protein and a nuclear lamina protein with the binding site located at the carboxy terminus. Which disease is linked to genomic alterations i... | amyotrophic lateral sclerosis | Medium | convergence | {"qa_id":"medium_convergence_00003","source_qa_id":"medium_convergence_three_branch_context_0672","difficulty":"medium","subtype":"convergence","detailed_subtype":"three_branch_context","locator":"context","question":"AKAP8L, LMNA, and TOPBP1 share more than one reported protein partner. Evidence concerning one of thes... | |
medium_convergence_00004 | BATF2 and CREBBP have overlapping extended protein-interaction neighborhoods containing several shared proteins. Evidence concerning one of these shared proteins describes a binding interaction that prevents the phosphorylation of a transcription factor during cellular differentiation. Which disease is linked to genomi... | obesity disorder | Medium | convergence | {"qa_id":"medium_convergence_00004","source_qa_id":"medium_convergence_two_branch_unequal_context_0770","difficulty":"medium","subtype":"convergence","detailed_subtype":"two_branch_unequal_context","locator":"context","question":"BATF2 and CREBBP have overlapping extended protein-interaction neighborhoods containing se... | |
medium_convergence_00005 | West Nile virus and Influenza A virus alter the expression of several genes in common. Expression data distinguish one of these genes: it was upregulated in bronchial epithelial cells with a log2 fold-change of about 1.35 and an adjusted p-value of about 0.00063. For which disease is this gene reported as a biomarker? | osteoporosis | Medium | convergence | {"qa_id":"medium_convergence_00005","source_qa_id":"medium_convergence_two_branch_equal_context_1124","difficulty":"medium","subtype":"convergence","detailed_subtype":"two_branch_equal_context","locator":"context","question":"West Nile virus and Influenza A virus alter the expression of several genes in common. Express... | |
medium_convergence_00006 | "KLF2, USP9X, and CTNNB1 share more than one reported protein partner. Evidence concerning one of th(...TRUNCATED) | lung cancer | Medium | convergence | "{\"qa_id\":\"medium_convergence_00006\",\"source_qa_id\":\"medium_convergence_three_branch_context_(...TRUNCATED) | |
medium_convergence_00007 | "West Nile virus and Human alphaherpesvirus 3 alter the expression of several genes in common. Expre(...TRUNCATED) | squamous cell carcinoma | Medium | convergence | "{\"qa_id\":\"medium_convergence_00007\",\"source_qa_id\":\"medium_convergence_two_branch_equal_cont(...TRUNCATED) | |
medium_convergence_00008 | "CLEC1B and CFTR share more than one reported protein partner. Evidence concerning one of these shar(...TRUNCATED) | hepatocellular carcinoma | Medium | convergence | "{\"qa_id\":\"medium_convergence_00008\",\"source_qa_id\":\"medium_convergence_two_branch_equal_cont(...TRUNCATED) | |
medium_convergence_00009 | "HEYL and VHL have overlapping extended protein-interaction neighborhoods containing several shared (...TRUNCATED) | osteoarthritis, knee | Medium | convergence | "{\"qa_id\":\"medium_convergence_00009\",\"source_qa_id\":\"medium_convergence_two_branch_unequal_co(...TRUNCATED) | |
medium_convergence_00010 | "POU2F2 and KMT2D share more than one reported protein partner. Evidence concerning one of these sha(...TRUNCATED) | asthma | Medium | convergence | "{\"qa_id\":\"medium_convergence_00010\",\"source_qa_id\":\"medium_convergence_two_branch_equal_cont(...TRUNCATED) |
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