Unnamed: 0 int64 0 2.34M | titles stringlengths 5 21.5M | abst stringlengths 1 21.5M |
|---|---|---|
2,400 | Atrial fibrillation storms. | Evolving pacemaker and device technology now allows the onset pattern of arrhythmias to be identified. It is recognised that some cardiac arrhythmias have a circadian pattern of onset and that ventricular arrhythmias can occur in clusters of electrical storms. The long-term follow-up of patients with an atrial defibril... |
2,401 | Acute myocardial infarction complicated by early onset of heart failure: safety and feasibility of interhospital transfer for coronary angioplasty. Subanalysis of Killip II-IV patients from the PRAGUE-1 study. | The objective of this study is to assess the feasibility and safety of interhospital transfer (within up to 60 minutes) for primary/rescue coronary angioplasty of patients with myocardial infarction (AMI) complicated by an early onset of acute heart failure (AHF) admitted to a community hospital without PCI facilities.... |
2,402 | The administration of alpha-melanocyte-stimulating hormone protects the ischemic/reperfused myocardium. | The contribution of alpha-melanocyte-stimulating hormone (alpha-MSH) treatment, an active fragment of adrenocorticotropic hormone (ACTH), to the recovery of postischemic cardiac function, infarct size, the incidence of reperfusion-induced ventricular fibrillation and apoptotic cell death was studied in ischemic/reperfu... |
2,403 | Aldosterone receptor blockade improves left ventricular remodeling and increases ventricular fibrillation threshold in experimental heart failure. | To investigate the effects of aldosterone receptor blockade in postinfarction heart failure.</AbstractText>Eighty-seven rats with moderate myocardial infarction were randomized to receive either no drug or canrenone, the active metabolite of spironolactone, 20 mg/kg/day, or ramipril, 1 mg/kg/day, or a combination of th... |
2,404 | Activation of peripheral delta opioid receptors eliminates cardiac electrical instability in a rat model of post-infarction cardiosclerosis via mitochondrial ATP-dependent K+ channels. | The effects of the selective delta-1 (delta(1)) opioid receptor agonist, DPDPE, and the selective delta(2) opioid receptor agonist, DSLET, have been studied on the ventricular fibrillation threshold (VFT) in rats with an experimental post-infarction cardiosclerosis (CS). It has been found that CS induced a significant ... |
2,405 | Stroke volumes and end-tidal carbon dioxide generated by precordial compression during ventricular fibrillation. | The objective of this study was to measure stroke volumes produced by precordial compression during cardiopulmonary resuscitation and to quantitate relationships of stroke volume to measurements of end-tidal carbon dioxide.</AbstractText>A prospective, observational animal study.</AbstractText>Medical research laborato... |
2,406 | Study of sudden cardiac deaths in young athletes. | Sudden cardiac deaths in athletes are usually due to underlying cardiovascular disease. The final pathway is usually ventricular fibrillation following hypertrophic cardiomyopathy and coronary artery anomalies in young persons below the age of 30 years. Sudden cardiac death in young is rare but remains as a source of c... |
2,407 | [Early defibrillation in the treatment of sudden cardiac arrest]. | Recovery from nontraumatic cardiac arrest depends on the presence of all the elements in the chain of survival. "Early defibrillation" is critical because ventricular fibrillation is the most common initial dysrhythmia of sudden cardiac arrest. Defibrillation is the only treatment, and survival from ventricular fibrill... |
2,408 | Surgical myocardial revascularization without extracorporeal circulation. | To assess the immediate postoperative period of patients undergoing myocardial revascularization without extracorporeal circulation with different types of grafts.</AbstractText>One hundred and twelve patients, 89 (79.5%) of whom were males, were revascularized without extracorporeal circulation. Their ages ranged from... |
2,409 | Dynamic pressure--flow velocity relationships in the human cerebral circulation. | The pressure-flow velocity relationship in the cerebral circulation is characterized by the critical closing pressure (CCP), which is the pressure at which flow ceases, and the linear slope of a plot between pressure and flow velocity. It has been suggested, but not validated, that CCP can be determined from arterial b... |
2,410 | Characterization of fibrillatory rhythms by ensemble vector directional analysis. | Recent studies have demonstrated that fibrillatory rhythms are not random phenomena but have definable patterns. However, standard mapping techniques may have limitations in their ability to identify the organization of fibrillation. The purpose of this study was to develop and apply a method, "ensemble vector mapping,... |
2,411 | Adenosine-sensitive wide-complex tachycardia: an uncommon variant of idiopathic fascicular ventricular tachycardia--a case report. | Most wide-complex tachycardias encountered in the emergency department (ED) are ventricular in origin, most commonly associated with structural heart disease. Ventricular tachyarrhythmias range in severity from life-threatening rhythms (eg, ventricular fibrillation and hemodynamically compromising ventricular tachycard... |
2,412 | [Antithrombotic prophylaxis in patients with ventricular dysfunction: critical review of the literature and new perspectives]. | Recent observational data suggest that mild or moderate heart failure is associated with an annual risk of stroke of approximately 1.2%. Indeed, it is possible that the major cause of sudden death in chronic heart failure is not related to arrhythmias, but to vascular occlusion. Anticoagulation may reduce the rate of e... |
2,413 | Ongoing trials of cardiac resynchronisation. | Heart failure is an increasingly common and debilitating condition for which pharmacological therapy has, so far, provided only partial relief. Despite medical therapy the overall prognosis remains poor with high rates of sudden death and death from progressive heart failure. Device based therapies offer considerable p... |
2,414 | Ventricular fibrillation during electrical cardioversion of pre-excited atrial fibrillation. | The Wolff-Parkinson-White syndrome can rarely present with pre-excited atrial fibrillation. In this condition the short refractory period of the accessory pathway can lead to rapid atrioventricular conduction. There is then a danger that at high heart rates the irregular broad complex tachycardia that results can deter... |
2,415 | Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker therapy for sinus node dysfunction. | Dual-chamber (DDDR) pacing preserves AV synchrony and may reduce heart failure (HF) and atrial fibrillation (AF) compared with ventricular (VVIR) pacing in sinus node dysfunction (SND). However, DDDR pacing often results in prolonged QRS durations (QRSd) as the result of right ventricular stimulation, and ventricular d... |
2,416 | Atrial fibrillation: hypertension as a causative agent, risk factor for complications, and potential therapeutic target. | Atrial fibrillation and hypertension are 2 prevalent, and often coexistent, conditions in the North American population. Their incidence increases with advancing age, and they are responsible for considerable morbidity and mortality. Although the relation between the 2 conditions has long been known, the treatment of h... |
2,417 | Suppressing arrhythmias in cardiac models using overdrive pacing and calcium channel blockers. | Recent findings indicate that ventricular fibrillation might arise from spiral wave chaos. Our objective in this computational study was to investigate wave interactions in excitable media and to explore the feasibility of using overdrive pacing to suppress spiral wave chaos. This work is based on the finding that in e... |
2,418 | Enhanced self-termination of re-entrant arrhythmias as a pharmacological strategy for antiarrhythmic action. | Ventricular tachycardia and fibrillation are potentially lethal cardiac arrhythmias generated by high frequency, irregular spatio-temporal electrical activity. Re-entrant propagation has been demonstrated as a mechanism generating these arrhythmias in computational and in vitro animal models of these arrhythmias. Re-en... |
2,419 | Wave front fragmentation due to ventricular geometry in a model of the rabbit heart. | The role of the heart's complex shape in causing the fragmentation of activation wave fronts characteristic of ventricular fibrillation (VF) has not been well studied. We used a finite element model of cardiac propagation capable of simulating functional reentry on curved two-dimensional surfaces to test the hypothesis... |
2,420 | Characterization of patterned irregularity in locally interacting, spatially extended systems: Ventricular fibrillation. | The re-entrant ventricular arrhythmias of monomorphic ventricular tachycardia and fibrillation are produced by abnormal spatio-temporal patterns of propagation in the ventricular myocardium. These behaviors can be described by solutions of reaction-diffusion equation excitable medium models. The direct comparison of su... |
2,421 | Alternans and higher-order rhythms in an ionic model of a sheet of ischemic ventricular muscle. | Life-threatening arrhythmias such as ventricular tachycardia and fibrillation often occur during acute myocardial ischemia. During the first few minutes following coronary occlusion, there is a gradual rise in the extracellular concentration of potassium ions ([K(+)](0)) within ischemic tissue. This elevation of [K(+)]... |
2,422 | Deterministic nonlinearity in ventricular fibrillation. | We provide numerical evidence that the electrocardiogram data collected from pigs during induced ventricular fibrillation cannot be described by a monotonic nonlinear transformation of linearly filtered noise. To establish this we use surrogate techniques and apply two test statistics: (1) the Takens' maximum likelihoo... |
2,423 | The correlation dimension of rat hearts in an experimentally controlled environment. | The electric response of several isolated rat hearts in a controlled environment was studied experimentally. The correlation dimension D(2) was estimated and was found to be between 4 and 6.5 when the response was nearly periodic. The variation of D(2) with the concentration of calcium was studied and a general trend o... |
2,424 | Acute reductions in ventricular myocardial tissue velocities after direct current cardioversion of atrial fibrillation. | Cardioversion by direct current (DC) and other methods can cause atrial "stunning." There are case reports of acute pulmonary edema after DC cardioversion, but whether acute ventricular dysfunction is a general consequence of DC cardioversion is unknown. We have investigated whether DC cardioversion acutely affects myo... |
2,425 | Clinical and electrophysiologic predictors of ventricular tachyarrhythmia recurrence in patients with implantable cardioverter defibrillators. | Not all patients experience recurrent sustained ventricular tachyarrhythmias after placement of an implantable cardioverter defibrillator (ICD). We evaluated the clinical and electrophysiologic predictors of ventricular tachycardia (VT) and ventricular fibrillation (VF) recurrence following ICD implantation.</AbstractT... |
2,426 | Natural history of Brugada syndrome: the prognostic value of programmed electrical stimulation of the heart. | The prognostic value of electrophysiologic studies in individuals with the syndrome of right bundle branch block and ST segment elevation in precordial leads V1 to V3 (Brugada syndrome) remains controversial. Our previous data from 252 individuals with the syndrome suggested that programmed ventricular stimulation had ... |
2,427 | Cardioprotection with sildenafil, a selective inhibitor of cyclic 3',5'-monophosphate-specific phosphodiesterase 5. | The effects of sildenafil (Viagra), a specific inhibitor of phosphodiesterase 5, on ischemic myocardium was examined using an isolated rat heart model. Rats were pretreated with sildenafil at doses ranging from 0.001 mg to 0.5 mg/kg body weight. After 60 min, isolated hearts were subjected to ischemia for 30 min follow... |
2,428 | [Study on the compatibility of composite herbal medicines of the lingguizhugan decoction]. | To study the compatibility of composite herbal medicines of the Ling Gui Zhu Gan Decoction.</AbstractText>Ethanol extract test solutions of the different combinations were prepared according to the orthogonal layout L16(4(5)). Pharmacologic experiments, such as the time of surviving of mice in shortage of oxygen in reg... |
2,429 | Defibrillatory action of glibenclamide is independent from ATP-sensitive K+ channels and free radicals. | This study investigated whether glibenclamide exerts a defibrillatory action and if this action is mediated by a blockade of ATP-sensitive K+ channels (K(ATP)) or by an anti-free radical mechanism. Aerobically perfused isolated rat hearts were subjected to 10 min of pacing-induced ventricular fibrillation (VF) followed... |
2,430 | Modulation of ventricular fibrillation in isolated perfused heart by dofetilide. | The authors studied the involvement of IKr potassium current in ventricular fibrillation during perfusion. Electrophysiologic parameters were measured before and after dofetilide administration (2.5, 7.5, and 12.5 x 10-7 M, n = 8) in isolated perfused feline hearts. During pacing, these parameters included epicardial c... |
2,431 | Late outcomes of mitral valve repair for floppy valves: Implications for asymptomatic patients. | We sought to evaluate the long-term results of mitral valve repair in patients with mitral regurgitation caused by floppy mitral valves and compare the outcomes of asymptomatic patients with those of symptomatic patients.</AbstractText>A retrospective review of 488 consecutive patients who had mitral valve repair for f... |
2,432 | Cardiopulmonary Resuscitation Guidelines 2000 update: what's happened since? | To examine the literature for new resuscitation science since the publication of the Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiac Care.</AbstractText>The two and a half years since the publication of the Guidelines 2000 have seen the advent of a number of new and important resuscitation studi... |
2,433 | Monitoring during cardiac arrest: are we there yet? | Advancements in electronic data acquisition have translated into improved monitoring of victims of cardiac arrest, but initial techniques remain direct observation of pulses and respirations. The most essential monitor continues to be the electrocardiogram. However, monitoring diastolic blood pressure, myocardial perfu... |
2,434 | Myocardial protection during resuscitation from cardiac arrest. | Successful treatment of cardiac arrest requires that an electrically stable and mechanically competent cardiac activity be promptly reestablished. However, many interventions used to attempt to reestablish cardiac activity may also inflict additional myocardial injury and, in turn, compromise resuscitability. In this r... |
2,435 | Strategies for reversing shock-resistant ventricular fibrillation. | Shock-resistant ventricular fibrillation is defined as ventricular fibrillation persisting after three defibrillation attempts. In approximately 10 to 25% of all cardiac arrests, shock-resistant ventricular fibrillation develops, and 87 to 98% of these patients die.</AbstractText>In the treatment of shock-resistant ven... |
2,436 | Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: the MIRACLE ICD Trial. | Cardiac resynchronization therapy (CRT) through biventricular pacing is an effective treatment for heart failure (HF) with a wide QRS; however, the outcomes of patients requiring CRT and implantable cardioverter defibrillator (ICD) therapy are unknown.</AbstractText>To examine the efficacy and safety of combined CRT an... |
2,437 | Enalapril decreases the incidence of atrial fibrillation in patients with left ventricular dysfunction: insight from the Studies Of Left Ventricular Dysfunction (SOLVD) trials. | Atrial fibrillation (AF) is frequently encountered in patients with heart failure (HF) and is also a predictor of morbidity and mortality in this population. Recent experimental studies have shown electrical and structural atrial remodeling with increased fibrosis in animals with HF and have suggested a preventive effe... |
2,438 | Results of early defibrillation program in Piacenza. | Defibrillation as soon as possible is the mainstay of modern emergency system in the treatment of sudden cardiac death. The emergency medical system (EMS) should be integrated with first responders in the community trained to use the semiautomatic external defibrillators (AED). Piacenza Progetto Vita is a European proj... |
2,439 | Potent antifibrillatory effects of intrapericardial nitroglycerin in the ischemic porcine heart. | We investigated the antiarrhythmic effects of intrapericardial nitroglycerin (NTG) during acute myocardial ischemia in the porcine heart.</AbstractText>Nitroglycerin is a nitric oxide donor that exerts potent effects on the cardiovascular system. Intrapericardial administration allows investigation of pharmacologic act... |
2,440 | Concomitant recovery of atrial mechanical and endocrine function after cardioversion in patients with persistent atrial fibrillation. | The purpose of this study was to evaluate left atrial mechanical function recovery and plasma atrial natriuretic peptide (ANP) release following successful cardioversion of persistent atrial fibrillation (AF).</AbstractText>Atrial fibrillation is characterized by functional deterioration, loss of atrial contraction, an... |
2,441 | The Australian Intervention Randomized Control of Rate in Atrial Fibrillation Trial (AIRCRAFT). | The Australian Intervention Randomized Control of Rate in Atrial Fibrillation Trial was a multicenter trial of atrioventricular junction ablation and pacing (AVJAP) compared with pharmacologic ventricular rate control (medication [MED]) in patients with mild to moderately symptomatic permanent atrial fibrillation (AF).... |
2,442 | Amiodarone for pharmacological cardioversion of recent-onset atrial fibrillation. | The efficacy and safety of amiodarone for pharmacological cardioversion of recent-onset atrial fibrillation was examined by reviewing the trials on the subject identified through a comprehensive literature search. Amiodarone has been used both intravenously (i.v.) and orally for the pharmacological cardioversion of rec... |
2,443 | Atrial stunning: determinants and cellular mechanisms. | Atrial stunning is a transient depression of atrial and atrial-appendage mechanical function after successful cardioversion of atrial fibrillation compared with its precardioversion state.</AbstractText>Atrial stunning associated with different methods of cardioversion of atrial fibrillation and the determinants and ce... |
2,444 | Quality of life evidence in the management of the individual patient with atrial fibrillation. | It is remarkable that in patients with paroxysmal AF not sufficiently controlled by pharmacological therapy, ablation and pacemaker treatment is highly effective and superior to drug therapy in controlling symptoms and improving quality of life. The discontinuation of drug therapy exposes patients to further recurrence... |
2,445 | Utility of patient-activated cardiac event recorders in the detection of cardiac arrhythmias. | Patient-activated event recorders are useful for the diagnosis of arrhythmia in patients with palpitation and presyncope. However, the utility of event recorders in patients suspected of arrhythmia but presenting with other symptoms is not clear. Furthermore, the factors influencing their utility have not been evaluate... |
2,446 | [Systemic embolism after reversion to sinusal rhythm of persistent atrial flutter]. | The incidence of embolism in atrial flutter has been underestimated in the routine clinical practice.</AbstractText>In this study the incidence of thromboembolic events after restoration of sinus rhythm (by catheter ablation or cardioversion) was compared in two groups of consecutive patients, with a different anticoag... |
2,447 | Significance of the morphological patterns of electrograms recorded during ventricular fibrillation: an experimental study. | Mapping techniques are used to study the significance of the morphological patterns of the electrograms (EGMs) obtained during VF in an experimental model. In 24 isolated rabbit heart preparations recordings were made of activation during VF using a multiple electrode (121 unipolar electrodes) positioned on the lateral... |
2,448 | Effects of sulfonylurea hypoglycemic agents and adenosine triphosphate dependent potassium channel antagonists on ventricular arrhythmias in patients with decompensated heart failure. | Hypoglycemic sulfonylureas block cardiac ATP-sensitive potassium channels (K(ATP)). The opening of these channels in cardiomyocytes can induce arrhythmias. In animal studies, sulfonylureas exert an antiarrhythmic effect on the ischemic myocardium, but data on human arrhythmic events are lacking. The study population in... |
2,449 | Late improvement in ventricular performance following internal cardioversion for persistent atrial fibrillation: an argument in support of concealed cardiomyopathy. | The aim of the study was to evaluate the time course of atrial and ventricular function improvement following internal atrial cardioversion in patients with structural heart disease. Twenty-nine patients with chronic persistent atrial fibrillation (AF) and underlying structural heart disease were followed by serial ech... |
2,450 | Cycle length-dependent repolarization changes during atrial fibrillation in the Brugada syndrome. | This is a case report of a patient with Brugada syndrome who developed paroxysmal atrial fibrillation. During the episode, beat-to-beat changes in ventricular repolarization were observed. These changes were a paradoxical ST-segment alteration after a short-coupled ventricular beat. These findings, not reported before,... |
2,451 | Two-dimensional analysis of ventricular fibrillation in the guinea pig. | Cardiac arrhythmias are undesirable electrical activity in the heart. Ventricular fibrillation (VF) is a fatal cardiac arrhythmia and is characterized by the breakdown of organized electrical activity in the ventricular myocardium. However, little is known about VF, partially because it is difficult to study and unders... |
2,452 | Increased cycle length variability during ventricular fibrillation: a novel predictor of arrhythmia recurrence. | To evaluate the clinical value of cycle length (CL) variability during ventricular fibrillation (VF), 26 patients who underwent implantable cardioverter defibrillator (ICD) implantation were enrolled. In VF induced for defibrillation testing, mean and SD of VFCL, mean successive differences (MSD) of VFCL, and coefficie... |
2,453 | Patients with chronic heart failure encountered in daily clinical practice are different from the "typical" patient enrolled in therapeutic trials. | The aim of this study was to compare the clinical characteristics of patients enrolled in randomized clinical trials on congestive heart failure treatment with those of real-world patients encountered in daily clinical practice.</AbstractText>We searched the Cochrane review methodology, Medline and SilverPlatter databa... |
2,454 | Survival with full neurologic recovery after prolonged cardiopulmonary resuscitation with a combination of vasopressin and epinephrine in pigs. | We sought to determine the effects of a combination of vasopressin and epinephrine on neurologic recovery in comparison with epinephrine alone and saline placebo alone in an established porcine model of prolonged cardiopulmonary resuscitation (CPR). After 4 min of cardiac arrest, followed by 3 min of basic life support... |
2,455 | [Sudden death in a normal heart. Idiopathic ventricular fibrillation. Review of the literature concerning one case]. | Idiopathic ventricular fibrillation is that which is produced in the absence of structural cardiac disease and of other identifiable causes of ventricular fibrillation such as cardiotoxicity, electrolytical alterations or hereditary predisposition. The case of a healthy male, aged 37, who was asymptomatic until the day... |
2,456 | [Cardiac arrhythmias during pregnancy--what to do?]. | Atrial premature beats are frequently diagnosed during pregnancy, supraventricular tachycardia (atrial tachycardia, AV nodal reentrant tachycardia, circus movement tachycardia) less frequently. For acute therapy, electrical cardioversion with 50-100 J is indicated in all unstable patients. In stable supraventricular ta... |
2,457 | [Pregnancy and cardiomyopathies]. | This overview on the topic of cardiomyopathy and gestation comprises the diagnostic and therapeutic options of patients with preexistent cardiomyopathies (dilated, hypertrophic, inflammatory, and others) and with cardiomyopathies which have been discovered during or in the 6 months following delivery. CARDIOMYOPATHIES ... |
2,458 | Temporal trends in sudden cardiac arrest: a 25-year emergency medical services perspective. | Little is known about temporal trends in survival and prognostic characteristics of patients with out-of-hospital cardiac arrest treated by emergency medical services (EMS). We hypothesized that an evolving combination of beneficial and adverse factors may contribute to temporal patterns of survival.</AbstractText>We e... |
2,459 | Nonrheumatic atrial fibrillation and left ventricular hypertrophy in the prognosis of reversible ischaemic neurological deficit. | Nonrheumatic atrial fibrillation (NRAF) and left ventricular hypertrophy (LVH) have long been recognised as risk factors for cerebral ischaemia and as predictors of recurrent vascular events. In the present study we aimed at determining the value of NRAF and LVH as predictors of recurrent vascular events in a cohort of... |
2,460 | Prognosis of congestive heart failure in patients with normal versus reduced ejection fractions: results from a cohort of 2,258 hospitalized patients. | Patients with congestive heart failure have an annual mortality of 10% to 20% depending on disease severity. Though one third of these patients have normal left ventricular (LV) ejection fraction (EF), their natural history is poorly defined. Small population-based studies have suggested a more benign prognosis for pat... |
2,461 | Long-term follow-up of single-lead VDD pacing. | Long-term outcomes of single-lead VDD pacing were studied retrospectively and partly prospectively. Records were analysed of 81 patients out of 133 in whom a single-lead VDD pacemaker was implanted between January 1993 and December 1997 and who attended a follow-up clinic more than two years after the implant. Forty-ei... |
2,462 | Comparative follow up of patients with implanted cardioverter-defibrillators after induction of sustained monomorphic ventricular tachycardias or ventricular fibrillation by programmed stimulation. | To investigate the prognostic value of induced monomorphic ventricular tachycardia (VT) and ventricular flutter or fibrillation (VF) during programmed electrical stimulation in patients with a high risk for sudden arrhythmogenic cardiac death.</AbstractText>Prospective cohort study.</AbstractText>102 patients at high r... |
2,463 | Successful resuscitation of a patient with electrical storm. | A 41 year old woman with type 2 diabetes, hypertension, and hyperlipidaemia but no known heart disease received 130 DC shocks for repeated cardiac arrests due to ventricular tachyarrhythmias over 48 hours. She was stabilised by intravenous amiodarone and had a defibrillator implanted. Serial ECGs did not change, but ra... |
2,464 | Tedisamil in coronary disease: additional benefits in the therapy of atrial fibrillation? | Atrial fibrillation has recently come into clinical and research focus. In particular, ventricular rate control has been carefully compared with atrial rhythm control. Additionally, the recent discovery of atrial stunning has initiated clinical and research interest in atrial remodeling. Atrial fibrillation is more lik... |
2,465 | Predicting defibrillation success by 'genetic' programming in patients with out-of-hospital cardiac arrest. | In some patients with ventricular fibrillation (VF) there may be a better chance of successful defibrillation after a period of chest compression and ventilation before the defibrillation attempt. It is therefore important to know whether a defibrillation attempt will be successful. The predictive power of a model deve... |
2,466 | Age and sex analyses of out-of-hospital cardiac arrest in Osaka, Japan. | To determine effective interventional targets for out-of-hospital cardiac arrests by analyzing the distribution characteristics of arrest patients according to age and sex with special emphasis on ventricular fibrillation (VF).</AbstractText>All patients who suffered out-of-hospital cardiac arrest in Osaka Prefecture, ... |
2,467 | Myocardial injury in children following resuscitation after cardiac arrest. | Myocardial dysfunction occurs immediately after successful cardiac resuscitation. Our purpose was to determine whether measurement of cardiac troponin I in children with acute out-of-hospital cardiac arrest predicts the severity of myocardial injury.</AbstractText>This prospective, observational study was performed in ... |
2,468 | Frequency of acute coronary syndrome in patients presenting to the emergency department with chest pain after methamphetamine use. | We reviewed the frequency of acute coronary syndrome (ACS) in patients presenting to our emergency department (ED) with chest pain after methamphetamine (MAP) use during a 2-year interval. Thirty-three patients (25 males, 8 females; average age 40.4 +/- 8.0 years) with a total of 36 visits met study inclusion criteria:... |
2,469 | [ECG changes in aortic valve defects]. | ECG is nowadays no longer the dominant way of diagnosing aortic valve diseases. The basis of accurate diagnosis of these diseases is clinical examination, ECHO and catheterization of the heart, which is essential in the great majority of valve diseases, in particular to rule out coronary changes. ECG is however importa... |
2,470 | [Electrocardiographic changes after heart transplantation]. | Electrocardiographic (ECG) changes are described after heart transplantation in almost 75% patients. During the early postoperative period the usual finding are conduction disorders which in 3-5% call for implantation of a pacemaker. The most frequent persisting disorder is bundle branch block which is of clinical impo... |
2,471 | Sudden death in noncoronary heart disease is associated with delayed paced ventricular activation. | Slowed or delayed myocardial activation and dispersed refractoriness predispose to reentrant excitation that may lead to ventricular fibrillation (VF). Increased ventricular electrogram duration (DeltaED) in response to extrastimuli and increased S1S2 coupling intervals at which electrogram duration starts to increase ... |
2,472 | Inherited arrhythmic disorders in Japan. | The clinical and genetic characteristics of inherited arrhythmic disorders in Japan are briefly summarized. The incidence of hereditary long QT syndrome (LQTS) in Japan seems comparable to that in western countries. The genotypes are mainly LQT1 and LQT2; LQT3 and other types are rare. Mutations found in Japanese LQTS ... |
2,473 | A newly characterized SCN5A mutation underlying Brugada syndrome unmasked by hyperthermia. | Febrile illness has been rarely reported to modulate ST segment elevation in right precordial leads on ECG or even precipitate ventricular fibrillation in patients with Brugada syndrome. We report the case of a patient whose Brugada ECG pattern was unmasked by hyperthermia secondary to acute cholangitis. Serial ECGs sh... |
2,474 | Site-specific arrhythmogenesis in patients with Brugada syndrome. | It has been believed that electrophysiologic abnormality of the epicardial region of the right ventricular free wall may play an important role in arrhythmogenesis of phase 2 reentry in Brugada syndrome, but clinical evidence of the occurrence of ventricular arrhythmias at the right ventricular free wall has not been e... |
2,475 | Arrhythmia surgery in association with complex congenital heart repairs excluding patients with fontan conversion. | Surgical arrhythmia therapy may be performed for patients failing the catheter ablation approach or incorporated into repair of complex congenital heart disease. Variations in atrial and ventricular anatomy that may limit the catheter approach can be directly addressed surgically assuring lesion depth and continuity of... |
2,476 | Administration of atrial natriuretic peptide attenuates reperfusion phenomena and preserves left ventricular regional wall motion after direct coronary angioplasty for acute myocardial infarction. | To evaluate the effects of synthetic human atrial natriuretic peptide (hANP) on myocardial reperfusion injury and left ventricular remodeling, 19 patients within 12 h of a first attack of anterior myocardial infarction (AMI) underwent intracoronary injection of 25 microg of hANP immediately after coronary angioplasty, ... |
2,477 | Alterations in atrial electrophysiology and tissue structure in a canine model of chronic atrial dilatation due to mitral regurgitation. | Clinically, chronic atrial dilatation is associated with an increased incidence of atrial fibrillation (AF), but the underlying mechanism is not clear. We have investigated atrial electrophysiology and tissue structure in a canine model of chronic atrial dilatation due to mitral regurgitation (MR).</AbstractText>Thirte... |
2,478 | Mechanical effects on arrhythmogenesis: from pipette to patient. | Mechanical stimuli delivered to the precordium can, if strong enough and timed at the beginning of the T-wave, induce ventricular premature beats or runs of ventricular tachycardia and even fibrillation. On the other hand, there are reports that a properly timed "chest thump" can terminate ventricular tachycardia, or c... |
2,479 | Mechanically induced sudden death in chest wall impact (commotio cordis). | Sudden death due to nonpenetrating chest wall impact in the absence of injury to the ribs, sternum and heart is known as commotio cordis. Although once thought rare, an increasing number of these events have been reported. Indeed, a significant percentage of deaths on the athletic field are due to chest wall impact. Co... |
2,480 | Mechano-electrical feedback underlying arrhythmias: the atrial fibrillation case. | Mechanoelectrical feedback (MEF) has become firmly established as a mechanism in which mechanical forces experienced by myocardial tissue or cell membranes convey alterations in electrophysiologic characteristics of such tissue. Observations to date mainly concern mechanically induced changes in action potential durati... |
2,481 | Combining electrical therapies for advanced heart failure: the Milan experience with biventricular pacing-defibrillation backup combination for primary prevention of sudden cardiac death. | Biventricular pacing (BVP) improves hemodynamics and symptoms in patients with heart failure with bundle branch block. Patients with a left ventricular ejection fraction <0.35 and ventricular tachyarrhythmias are at risk of sudden cardiac death, and they benefit most from implantable cardioverter defibrillators (ICD... |
2,482 | Prevention and management of chronic heart failure with electrical therapy. | Sudden cardiac death is responsible for >40% of patients with heart failure losing their lives. Thus, the prevention of life-threatening cardiac arrhythmias is a major goal in the management of heart failure. In several randomized clinical trials, electrical therapy with the implantable cardioverter defibrillator (I... |
2,483 | Pharmacologic therapy for patients with chronic heart failure and reduced systolic function: review of trials and practical considerations. | Heart failure (HF) is a complex clinical syndrome resulting from any structural or functional cardiac disorder impairing the ability of the ventricles to fill with or eject blood. The approach to pharmacologic treatment has become a combined preventive and symptomatic management strategy. Ideally, treatment should be i... |
2,484 | Echocardiographic changes and predictors of arrhythmia recurrence after long-term use of the atrial defibrillator. | The patient-activated atrial defibrillator allows patients to cardiovert themselves from atrial fibrillation soon after the onset of symptoms. The long-term effects of early cardioversion from persistent atrial fibrillation on left ventricular performance and left atrial size are unknown.</AbstractText>Eighteen patient... |
2,485 | Diagnosis and treatment of sick sinus syndrome. | Sick sinus syndrome comprises a variety of conditions involving sinus node dysfunction and commonly affects elderly persons. While the syndrome can have many causes, it usually is idiopathic. Patients may experience syncope, pre-syncope, palpitations, or dizziness; however, they often are asymptomatic or have subtle or... |
2,486 | Electron microscopic study of intrinsic cardiac ganglia in the adult human. | The aim of the present study was to describe in detail the ultrastructure of intrinsic cardiac ganglionic cells in the healthy human as these cells appear to be directly involved in the development of tachycardia, atrioventricular block, ventricular fibrillation, and sudden cardiac death. Tissues examined in this study... |
2,487 | Correlation of the Tei index with invasive measurements of ventricular function in a porcine model. | The Doppler myocardial performance (Tei) index has been reported to be clinically useful in assessing left ventricular systolic and diastolic function in both adults and children. However, there are limited data to compare the Tei index with invasive measurements of ventricular function. We used a porcine model to dire... |
2,488 | [Risk of ventricular fibrillation in patients with Wolff-Parkinson White syndrome]. | A 16-year-old boy suddenly fell off his stool, a 26-year-old man had persistent palpitations and a 29-year-old man was reanimated without an incriminating anamnesis. The diagnosis 'Wolff-Parkinson-White(WPW)-syndrome' was made in all three cases. The boy died as a result of postanoxic neurological injury; in the two me... |
2,489 | Implications of the LIFE trial. | The recent Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) study was conducted in patients with essential hypertension with electrocardiogram evidence of left ventricular hypertrophy. This showed that losartan compared to atenolol resulted in a significant reduction in the primary endpoint of cardio... |
2,490 | Electrophysiological effects of a single intravenous administration of ivabradine (S 16257) in adult patients with normal baseline electrophysiology. | Ivabradine is a heart rate-lowering agent that selectively inhibits the pacemaker current, I(f), in the sinoatrial node. The objective of this study was to evaluate the effects of a single intravenous administration of ivabradine on cardiac electrophysiological parameters in patients with normal baseline electrophysiol... |
2,491 | Atrial fibrillation in the pacemaker clinic. | Electrocardiographic (ECG) recognition of the underlying rhythm in patients with ventricular pacing can be difficult. Atrial fibrillation (AF) in particular may go unreported.</AbstractText>To compare the underlying atrial rhythm determined in the pacemaker clinic with the 12-lead ECG interpretation of the atrial rhyth... |
2,492 | Biphasic shocks compared with monophasic damped sine wave shocks for direct ventricular defibrillation during open heart surgery. | Biphasic waveform shocks are more effective than monophasic shocks for transchest ventricular defibrillation, atrial cardioversion, and defibrillation with implantable defibrillators but have not been studied for open chest, intraoperative defibrillation. This prospective, blinded, randomized clinical study compares bi... |
2,493 | Electrical heterogeneity and arrhythmogenesis: importance of conduction velocity dispersion. | An experimental model of conduction velocity (CV) and refractory period dispersion was established to determine which variable is a determinant of myocardial vulnerability. Anesthetized swine were instrumented with a left anterior descending coronary artery catheter for regional infusion of lidocaine (n = 6), low-dose ... |
2,494 | SNC-80-induced preconditioning: selective activation of the mitochondrial adenosine triphosphate-gated potassium channel. | Pharmacologic preconditioning by delta-opioid agonists occurs via activation of an adenosine triphosphate (ATP)-gated potassium channel (I(KATP)). Opening of mitochondrial I(KATP) confers pharmacologic preconditioning whereas opening the sarcolemmal I(KATP) shortens action potential duration and is proarrhythmic. This ... |
2,495 | Combined sodium and calcium channel blockade in prevention of lethal arrhythmias. | Anti-arrhythmic compounds with multiple actions reduce arrhythmic death risk in post-myocardial infarction (MI) patients. Sudden death prevention, however, may rely more on implantable defibrillators than anti-arrhythmic drugs due to ineffective pharmacologic intervention. Widespread use of implantable defibrillators s... |
2,496 | Deleterious effects of acute treatment with a peroxisome proliferator-activated receptor-gamma activator in myocardial ischemia and reperfusion in pigs. | Thiazolidinediones exert electrophysiologic effects in noncardiac cells in vitro, but to date there have been no reports of effects on cardiac rhythm. We previously demonstrated that chronic pretreatment with a thiazolidinedione peroxisome proliferator-activated receptor (PPAR)-gamma activator, troglitazone, improves r... |
2,497 | Atrial infarction: a neglected electrocardiographic sign with important clinical implications. | A case of atrial infarction in the setting of an acute infero-posterolateral and right ventricular myocardial infarction is reported. Although often only a subtle ECG sign, this finding must make the physician aware of possible complications, such as arrhythmias (atrial fibrillation, sinus bradycardia, and AV conductio... |
2,498 | Detection of proarrhythmia in the female rabbit heart: blinded validation. | Reliable detection of drug-induced proarrhythmia, especially the potential for polymorphic ventricular tachycardia, is of great importance in the development of new compounds that are safe for the heart and was evaluated in a blinded study.</AbstractText>In 142 female rabbits, the monophasic action potential was used t... |
2,499 | Effects of glucose-induced insulin secretion on ST segment elevation in the Brugada syndrome. | ST segment elevation in patients with Brugada syndrome is known to fluctuate occasionally, influenced by multiple factors. Insulin has been shown to affect QT dispersion in healthy volunteers, as well as result in abnormality of ventricular repolarization in patients with congenital long QT syndrome.</AbstractText>To a... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.