id int64 225 5.32k | context stringlengths 2.88k 70.8k | question stringlengths 11 194 | answers dict | is_impossible bool 1
class |
|---|---|---|---|---|
4,106 | Etiology of Influenza-Like Illnesses from Sentinel Network Practitioners in Réunion Island, 2011-2012
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031398/
SHA: f5ff89ebfdd0375d034c112c6c1c7e163fa69a0c
Authors: Brottet, Elise; Jaffar-Bandjee, Marie-Christine; Li-Pat-Yuen, Ghislaine; Filleul, Laurent
Date: 2016-09-21... | Which two seasons were identified for trends in virus circulation?? | {
"answer_start": [
6299
],
"text": [
"winter season during weeks 23 to 39 between June and September and summer season during the rest of the year."
]
} | false |
4,107 | Etiology of Influenza-Like Illnesses from Sentinel Network Practitioners in Réunion Island, 2011-2012
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031398/
SHA: f5ff89ebfdd0375d034c112c6c1c7e163fa69a0c
Authors: Brottet, Elise; Jaffar-Bandjee, Marie-Christine; Li-Pat-Yuen, Ghislaine; Filleul, Laurent
Date: 2016-09-21... | Which were the most frequently identified respiratory pathogens? | {
"answer_start": [
7961
],
"text": [
" rhinovirus (23.4%), influenza A not H1N1 (21.2%) and influenza B (12.6%) "
]
} | false |
4,108 | Etiology of Influenza-Like Illnesses from Sentinel Network Practitioners in Réunion Island, 2011-2012
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031398/
SHA: f5ff89ebfdd0375d034c112c6c1c7e163fa69a0c
Authors: Brottet, Elise; Jaffar-Bandjee, Marie-Christine; Li-Pat-Yuen, Ghislaine; Filleul, Laurent
Date: 2016-09-21... | What were detected only in summer? | {
"answer_start": [
8504
],
"text": [
"Human Metapneumovirus, RSV A and B, and influenza A(H1N1)pdm09"
]
} | false |
4,109 | Etiology of Influenza-Like Illnesses from Sentinel Network Practitioners in Réunion Island, 2011-2012
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031398/
SHA: f5ff89ebfdd0375d034c112c6c1c7e163fa69a0c
Authors: Brottet, Elise; Jaffar-Bandjee, Marie-Christine; Li-Pat-Yuen, Ghislaine; Filleul, Laurent
Date: 2016-09-21... | What viruses were identified only in winter? | {
"answer_start": [
8769
],
"text": [
"Parainfluenza 1,2 and 4 viruses"
]
} | false |
4,111 | Etiology of Influenza-Like Illnesses from Sentinel Network Practitioners in Réunion Island, 2011-2012
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031398/
SHA: f5ff89ebfdd0375d034c112c6c1c7e163fa69a0c
Authors: Brottet, Elise; Jaffar-Bandjee, Marie-Christine; Li-Pat-Yuen, Ghislaine; Filleul, Laurent
Date: 2016-09-21... | Respiratory viral pathogens were present in what percentage of samples? | {
"answer_start": [
9941
],
"text": [
"76.1"
]
} | false |
4,112 | Etiology of Influenza-Like Illnesses from Sentinel Network Practitioners in Réunion Island, 2011-2012
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031398/
SHA: f5ff89ebfdd0375d034c112c6c1c7e163fa69a0c
Authors: Brottet, Elise; Jaffar-Bandjee, Marie-Christine; Li-Pat-Yuen, Ghislaine; Filleul, Laurent
Date: 2016-09-21... | What did the study highlight? | {
"answer_start": [
10537
],
"text": [
"several co-infections, showing that concomitant the multiple etiology of ILI"
]
} | false |
4,113 | Etiology of Influenza-Like Illnesses from Sentinel Network Practitioners in Réunion Island, 2011-2012
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031398/
SHA: f5ff89ebfdd0375d034c112c6c1c7e163fa69a0c
Authors: Brottet, Elise; Jaffar-Bandjee, Marie-Christine; Li-Pat-Yuen, Ghislaine; Filleul, Laurent
Date: 2016-09-21... | How many swabs remained without etiology? | {
"answer_start": [
11673
],
"text": [
" 53 swabs, representing 24% of the sample"
]
} | false |
4,114 | Etiology of Influenza-Like Illnesses from Sentinel Network Practitioners in Réunion Island, 2011-2012
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031398/
SHA: f5ff89ebfdd0375d034c112c6c1c7e163fa69a0c
Authors: Brottet, Elise; Jaffar-Bandjee, Marie-Christine; Li-Pat-Yuen, Ghislaine; Filleul, Laurent
Date: 2016-09-21... | What hypotheses can explain this result? | {
"answer_start": [
11842
],
"text": [
" a poor quality of swabs, preventing from identifying a pathogen, noninfectious causes or other pathogens not included in the multiplex PCR."
]
} | false |
4,115 | Etiology of Influenza-Like Illnesses from Sentinel Network Practitioners in Réunion Island, 2011-2012
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031398/
SHA: f5ff89ebfdd0375d034c112c6c1c7e163fa69a0c
Authors: Brottet, Elise; Jaffar-Bandjee, Marie-Christine; Li-Pat-Yuen, Ghislaine; Filleul, Laurent
Date: 2016-09-21... | What could not be tested for? | {
"answer_start": [
12032
],
"text": [
"RNAse P, a marker of human cells,"
]
} | false |
4,116 | Etiology of Influenza-Like Illnesses from Sentinel Network Practitioners in Réunion Island, 2011-2012
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031398/
SHA: f5ff89ebfdd0375d034c112c6c1c7e163fa69a0c
Authors: Brottet, Elise; Jaffar-Bandjee, Marie-Christine; Li-Pat-Yuen, Ghislaine; Filleul, Laurent
Date: 2016-09-21... | What does this study highlight? | {
"answer_start": [
13427
],
"text": [
" circulation of multiple pathogens in Réunion Island throughout the year."
]
} | false |
4,117 | Etiology of Influenza-Like Illnesses from Sentinel Network Practitioners in Réunion Island, 2011-2012
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031398/
SHA: f5ff89ebfdd0375d034c112c6c1c7e163fa69a0c
Authors: Brottet, Elise; Jaffar-Bandjee, Marie-Christine; Li-Pat-Yuen, Ghislaine; Filleul, Laurent
Date: 2016-09-21... | What does the study show? | {
"answer_start": [
13510
],
"text": [
"that ILI is not specific to influenza and so it is essential to have biological results in order to establish the differential diagnosis and thus explain the etiology of symptoms."
]
} | false |
4,118 | Etiology of Influenza-Like Illnesses from Sentinel Network Practitioners in Réunion Island, 2011-2012
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031398/
SHA: f5ff89ebfdd0375d034c112c6c1c7e163fa69a0c
Authors: Brottet, Elise; Jaffar-Bandjee, Marie-Christine; Li-Pat-Yuen, Ghislaine; Filleul, Laurent
Date: 2016-09-21... | What would be interesting to do? | {
"answer_start": [
14153
],
"text": [
"to repeat this study every 3 or 5 years adding clinical data to monitor the evolution of respiratory pathogens in Réunion Island over time."
]
} | false |
3,593 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | What is it most similar to? | {
"answer_start": [
1035
],
"text": [
"bat beta-coronaviruses, with the highest being >96% identity "
]
} | false |
3,589 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | How many people were affected as of Feb. 10, 2020? | {
"answer_start": [
447
],
"text": [
"greater than 40,000"
]
} | false |
3,590 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | How is the SARS-CoV-2 referred to? | {
"answer_start": [
629
],
"text": [
" as coronavirus disease discovered in 2019 (COVID-19)"
]
} | false |
3,592 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | How much similarity the SARS-COV-2 genome sequence has with SARS-COV? | {
"answer_start": [
975
],
"text": [
"∼80% identity with SARS-CoV"
]
} | false |
3,594 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | what similarity human SARS-COV and palm civet SARSlike COV share? | {
"answer_start": [
1505
],
"text": [
" 99.8% homology, with a total of 202 single-nucleotide (nt) variations (SNVs) identified across the genome "
]
} | false |
3,595 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | How much is the difference between the human SARS-CoV-2 and the bat RaTG13-CoV? | {
"answer_start": [
1639
],
"text": [
"greater than 1,100 nt "
]
} | false |
3,596 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | Why is it highly unlikely that RaTG13 CoV is the immediate source of SARS-CoV-2. | {
"answer_start": [
1737
],
"text": [
"are distributed throughout the genome in a naturally occurring pattern following the evolutionary characteristics typical of CoVs"
]
} | false |
3,597 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | What are the most revealing signs that SARS-CoV-2 evolved by natural evolution. | {
"answer_start": [
1945
],
"text": [
"The absence of a logical targeted pattern in the new viral sequences and a close relative in a wildlife species (bat"
]
} | false |
3,598 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | What did the Nature Medicine paper report? | {
"answer_start": [
2585
],
"text": [
"the construction of a chimeric CoV with a bat CoV S gene (SHC014) in the backbone of a SARS CoV that has adapted to infect mice (MA15) and is capable of infecting human cells"
]
} | false |
3,599 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | Why does the claim lack any scientific basis? | {
"answer_start": [
2835
],
"text": [
" because of significant divergence in the genetic sequence of this construct with the new SARS-CoV-2 (>5,000 nucleotides)."
]
} | false |
3,600 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | How was the mouse-adapted SARS virus (MA15) generated? | {
"answer_start": [
3013
],
"text": [
"by serial passage of an infectious wildtype SARS CoV clone in the respiratory tract of BALB/c mice."
]
} | false |
3,601 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | How did the SARS-CoV gain elevated replication and lung pathogenesis in aged mice ? | {
"answer_start": [
3229
],
"text": [
"due to six coding genetic mutations associated with mouse adaptation. "
]
} | false |
3,602 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | Why is it likely that MA15 is highly attenuated to replicate in human cells? | {
"answer_start": [
3383
],
"text": [
"due to the mouse adaptation."
]
} | false |
3,604 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | Why were civets proposed to be an intermediate host of the bat-CoVs, capable of spreading SARS CoV to humans? | {
"answer_start": [
3414
],
"text": [
"t was proposed that the S gene from bat-derived CoV, unlike that from human patients-or civetsderived viruses, was unable to use human ACE2 as a receptor for entry into human cells "
]
} | false |
3,605 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | What was the finding in 2013? | {
"answer_start": [
3738
],
"text": [
"several novel bat coronaviruses were isolated from Chinese horseshoe bats and the bat SARS-like or SL-CoV-WIV1 was able to use ACE2 from humans, civets and Chinese horseshoe bats for entry "
]
} | false |
3,606 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | Why is it proposed that some bat SL-CoVs may be able to directly infect human hosts? | {
"answer_start": [
3933
],
"text": [
"Combined with evolutionary evidence that the bat ACE2 gene has been positively selected at the same contact sites as the human ACE2 gene for interacting with SARS CoV ["
]
} | false |
3,607 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | What was done to test if an intermediate host may not be necessary and that some bat SL-CoVs may be able to directly infect human hosts. T | {
"answer_start": [
4277
],
"text": [
" the exact S gene from bat coronavirus SL-SHC014 was synthesized and used to generate a chimeric virus in the mouse adapted MA15 SARS-CoV backbone. "
]
} | false |
3,608 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | What were the results of this test? | {
"answer_start": [
4425
],
"text": [
"The resultant SL-SHC014-MA15 virus could indeed efficiently use human ACE2 and replicate in primary human airway cells to similar titres as epidemic strains of SARS-CoV. While SL-SHC014-MA15 can replicate efficiently in young and aged mouse lungs, infection was atten... | false |
3,609 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | Why were experiments with SL-SHC014-MA15 chimeric virus were later restricted? | {
"answer_start": [
5059
],
"text": [
"as gain of function (GOF) studies under the US government-mandated pause policy "
]
} | false |
3,610 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | Why is there no credible evidence to support the claim that the SARS-CoV-2 is derived from the chimeric SL-SHC014-MA15 virus? | {
"answer_start": [
5474
],
"text": [
"upon careful phylogenetic analyses by multiple international groups [5, 14] , the SARS-CoV-2 is undoubtedly distinct from SL-SHC014-MA15, with >6,000 nucleotide differences across the whole genome."
]
} | false |
3,611 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | What did the rumour that the virus was made by humans in the lab, claim? | {
"answer_start": [
6049
],
"text": [
"that SARS-CoV-2 has HIV sequence in it and was thus likely generated in the laboratory. I"
]
} | false |
3,612 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | What was reported in a rebuttal paper led by an HIV-1 virologist Dr. Feng Gao? | {
"answer_start": [
6197
],
"text": [
" they used careful bioinformatics analyses to demonstrate that the original claim of multiple HIV insertions into the SARS-CoV-2 is not HIV-1 specific but random "
]
} | false |
3,613 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | What happened to the report with initial claims? | {
"answer_start": [
6365
],
"text": [
" Because of the many concerns raised by the international community, the authors who made the initial claim have already withdrawn this report."
]
} | false |
3,614 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | What is the difference between evolution and synthetic constructs? | {
"answer_start": [
6510
],
"text": [
"Evolution is stepwise and accrues mutations gradually over time, whereas synthetic constructs would typically use a known backbone and introduce logical or targeted changes instead of the randomly occurring mutations that are present in naturally isolated viruses suc... | false |
3,615 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | What is the conclusion of this report? | {
"answer_start": [
6810
],
"text": [
" there is currently no credible evidence to support the claim that SARS-CoV-2 originated from a laboratory-engineered CoV. It is more likely that SARS-CoV-2 is a recombinant CoV generated in nature between a bat CoV and another coronavirus in an intermediate animal h... | false |
3,616 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | What is the conclusion of this report? | {
"answer_start": [
7082
],
"text": [
"More studies are needed to explore this possibility and resolve the natural origin of SARS-CoV-2. We should emphasize that, although SARS-CoV-2 shows no evidence of laboratory origin, viruses with such great public health threats must be handled properly in the labor... | false |
4,574 | No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054935/
SHA: 5a9154aee79901dd8fecd58b7bcd9b7351102d24
Authors: Liu, Shan-Lu; Saif, Linda J.; Weiss, Susan R.; Su, Lishan
Date: 2020-02-26
DOI: 10.1080/22221751.2020.1733440
License: cc-by
... | what is the clinical manifestation similar to? | {
"answer_start": [
859
],
"text": [
"to that of the severe acute respiratory syndrome (SARS) caused by SARS-CoV. "
]
} | false |
5,173 | Effectiveness of zinc supplementation on diarrhea and average daily gain in pre-weaned dairy calves: A double-blind, block-randomized, placebo-controlled clinical trial
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619766/
SHA: ef20a0cd67ce018cf061f154bd8be9d0e58d0f23
Authors: Feldmann, Hillary R.; Williams, Deniece... | What was the purpose of the research? | {
"answer_start": [
500
],
"text": [
"to evaluate the effectiveness of zinc supplementation on diarrhea and average daily weight gain (ADG) in pre-weaned dairy calves"
]
} | false |
5,174 | Effectiveness of zinc supplementation on diarrhea and average daily gain in pre-weaned dairy calves: A double-blind, block-randomized, placebo-controlled clinical trial
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619766/
SHA: ef20a0cd67ce018cf061f154bd8be9d0e58d0f23
Authors: Feldmann, Hillary R.; Williams, Deniece... | What preventative measure has been taken to decrease the incidence of diarrhea in children? | {
"answer_start": [
3167
],
"text": [
"Zinc supplementation"
]
} | false |
4,442 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What led to a great increase in their study among virologists worldwide? | {
"answer_start": [
533
],
"text": [
"an outbreak in 1993–94 in the southwestern United States"
]
} | false |
4,443 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | How many hantaviral genotypes have been described | {
"answer_start": [
658
],
"text": [
"Well over 40"
]
} | false |
4,444 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | How many of them are pathogenic for humans? | {
"answer_start": [
748
],
"text": [
"nearly half of them"
]
} | false |
4,445 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What do Hantaviruses cause in their reservoir hosts? | {
"answer_start": [
810
],
"text": [
"persistent infections"
]
} | false |
4,446 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What does hantavirus human disease manifest as? | {
"answer_start": [
907
],
"text": [
" a cardiopulmonary compromise, hantavirus cardiopulmonary syndrome (HCPS)"
]
} | false |
4,448 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is the case-fatality ratios, for the most common viral serotypes? | {
"answer_start": [
1046
],
"text": [
"between 30% and 40%"
]
} | false |
4,449 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What are among the factors that may have increased the human caseload of HCPS between 1993 and the present? | {
"answer_start": [
1066
],
"text": [
" Habitat disturbance and larger-scale ecological disturbances, perhaps including climate change,"
]
} | false |
4,450 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What do authors consider in this study? | {
"answer_start": [
1282
],
"text": [
" the features that influence the structure of host population dynamics that may lead to viral outbreaks"
]
} | false |
4,451 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What do authors consider in this study? | {
"answer_start": [
1398
],
"text": [
"the macromolecular determinants of hantaviruses that have been regarded as having potential contribution to pathogenicity."
]
} | false |
4,452 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | Which diseases are a major concern among scientists studying infectious diseases? | {
"answer_start": [
1609
],
"text": [
" emerging zoonotic diseases"
]
} | false |
4,453 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What may alter population disease dynamics and lead to the emergence of zoonotic infections? | {
"answer_start": [
1753
],
"text": [
"Changes in biotic and abiotic conditions"
]
} | false |
4,454 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | Which are among the conspicuous examples which challenge prevention and control measures of public health systems? | {
"answer_start": [
2120
],
"text": [
" influenza A, Ebola virus, hepatitis C virus, severe adult respiratory distress (SARS), coronavirus, and human immunodeficiency virus"
]
} | false |
4,456 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | More recently, what did outbreaks of several viral-related diseases that have emerged or re-emerged, involve? | {
"answer_start": [
2807
],
"text": [
"hantaviruses, and the expansion of the geographic range of West Nile virus."
]
} | false |
4,455 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What did, In the last century, outbreaks of viral-related diseases that have emerged or re-emerged, involve? | {
"answer_start": [
2755
],
"text": [
"arenaviruses and dengue viruses"
]
} | false |
4,457 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | Among zoonotic diseases, what are hosts of several pathogenic RNA viruses? | {
"answer_start": [
2908
],
"text": [
"small mammals"
]
} | false |
4,458 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | Which pathogenic RNA viruses are hosted by small mammals? | {
"answer_start": [
2977
],
"text": [
" Arenaviridae and Bunyaviridae: Hantavirus "
]
} | false |
4,459 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | When did Hantavirus infections became a concern in the Americas? | {
"answer_start": [
3228
],
"text": [
" disease, hantavirus cardiopulmonary syndrome, HCPS (or hantavirus pulmonary syndrome), was linked to "
]
} | false |
4,460 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What was the hantavirus cardiopulmonary syndrome, HCPS (or hantavirus pulmonary syndrome), linked to? | {
"answer_start": [
3330
],
"text": [
"infection by the newly-discovered Sin Nombre virus (SNV)"
]
} | false |
4,461 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What was identified as the reservoir of SNV? | {
"answer_start": [
3391
],
"text": [
" the rodent Peromyscus maniculatus (deer mouse)"
]
} | false |
4,462 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What did a review of ancient Chinese writings in 960 AD, reveal? | {
"answer_start": [
3621
],
"text": [
"descriptions closely resembling hemorrhagic fever with renal syndrome (HFRS), the syndrome caused by Old World hantaviruses"
]
} | false |
4,463 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | How was HFRS first brought to the attention of western medicine ? | {
"answer_start": [
4055
],
"text": [
"with an outbreak that occurred among United Nations troops during the Korean conflict between 1951 and 1954"
]
} | false |
4,464 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is HTNV? | {
"answer_start": [
4256
],
"text": [
" etiologic agent, Hantaan virus"
]
} | false |
4,465 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | Where was HTNV isolated from? | {
"answer_start": [
4308
],
"text": [
" from the striped field mouse Apodemus agrarius,"
]
} | false |
4,466 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | Which new genus was the virus later found to represent? | {
"answer_start": [
4567
],
"text": [
"Hantavirus of the family Bunyaviridae"
]
} | false |
4,467 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | Which was the first hantavirus to be isolated? | {
"answer_start": [
4725
],
"text": [
"The categorization of hantaviruses as belonging to the family Bunyaviridae is due in part to"
]
} | false |
4,468 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is the categorization of hantaviruses as belonging to the family Bunyaviridae due in part to? | {
"answer_start": [
4817
],
"text": [
" the consistent presence of three RNA genomes that are circularized in vivo as a result of the presence of terminal complementary nucleotides that help fold the genome into a -hairpin‖ morphology,"
]
} | false |
4,469 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What was the hairpin morphology first described for? | {
"answer_start": [
5038
],
"text": [
"Uukuniemi phlebovirus "
]
} | false |
4,470 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | How is the the precursor form GPC processed, during virus maturation? | {
"answer_start": [
5376
],
"text": [
"a membrane -bound protease into Gn and Gc, a cleavage that occurs"
]
} | false |
4,471 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | When does the cleavage appear to be signaled? | {
"answer_start": [
5471
],
"text": [
"after the conserved peptide signal WAASA at the C-terminal of Gn "
]
} | false |
4,472 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | Why must the two proteins Gn and Gc be co-expressed? | {
"answer_start": [
5727
],
"text": [
"to allow them stability so that the two can be assembled correctly in the Golg"
]
} | false |
4,473 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | Which two distinct cellular receptors the glycoproteins are the known or presumed ligands for? | {
"answer_start": [
6200
],
"text": [
" the 3 integrin chain and decay accelerating factor, or DAF"
]
} | false |
4,474 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is the underlying premise for many of these studies? | {
"answer_start": [
8311
],
"text": [
" blunt any pathological response in the host ["
]
} | false |
4,482 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is the premise for apathogenic forms to blunt any pathological response in the host? | {
"answer_start": [
8136
],
"text": [
"would tend to induce an earlier innate response that would render it more likely that the virus would be quickly cleared or rendered less competent in its replication"
]
} | false |
4,483 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | Which proteins and mRNAs prominently induced by hantaviruses include? | {
"answer_start": [
10002
],
"text": [
"hantaviruses have been identified as adversely affecting"
]
} | false |
4,492 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What have hantaviruses been identified as adversely affect? | {
"answer_start": [
10059
],
"text": [
"endothelial migration over substrata "
]
} | false |
4,493 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What have hantaviruses been identified in potentiating? | {
"answer_start": [
10115
],
"text": [
" VEG-F-induced endothelial permeability"
]
} | false |
4,494 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is N-protein? | {
"answer_start": [
10217
],
"text": [
"a structural component of the viral nucleocapsid"
]
} | false |
4,495 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What does the N-protein, as an RNA-binding protein, do? | {
"answer_start": [
10341
],
"text": [
"engages the hairpin termini of the genomic segments with high affinity"
]
} | false |
4,496 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | As an RNA-binding protein that engages the hairpin termini of the genomic segments, what does the N-protein of hantavirus do? | {
"answer_start": [
10422
],
"text": [
" it limits the access of the RNA to host nucleases "
]
} | false |
4,497 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | As an RNA-binding protein that engages the hairpin termini of the genomic segments, what does the N-protein of hantavirus do? | {
"answer_start": [
10476
],
"text": [
" helps to render viral replication a closed process within the cytoplasm"
]
} | false |
4,498 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What does the N-protein act as? | {
"answer_start": [
10566
],
"text": [
"a peripheral membrane protein"
]
} | false |
4,499 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What can some of the other activities of N have, be linked to? | {
"answer_start": [
10910
],
"text": [
" to the interference with an array of the intracellular processes of the normal cell"
]
} | false |
4,500 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What can some of the other activities of N have, be linked to? | {
"answer_start": [
10857
],
"text": [
" to fundamental requirements of replication"
]
} | false |
4,501 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is N also reported to interact with? | {
"answer_start": [
11219
],
"text": [
"with actin microfilaments, and the SUMO-1 protein"
]
} | false |
4,502 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | How do the viral RNAs become concentrated in P bodies during hantavirus infection? | {
"answer_start": [
11940
],
"text": [
" through their interaction with N and DCP1"
]
} | false |
4,503 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What have confocal microscopy and biochemical-inhibitor studies shown? | {
"answer_start": [
13763
],
"text": [
" that N tracks along microtubules"
]
} | false |
4,504 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What have confocal microscopy and biochemical-inhibitor studies shown on what N tracks? | {
"answer_start": [
13801
],
"text": [
"not with actin filaments "
]
} | false |
4,505 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is the ultimate destination for N, for its assembly into viral particles? | {
"answer_start": [
13906
],
"text": [
"the Golgi"
]
} | false |
4,506 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | How does it traffic? | {
"answer_start": [
13938
],
"text": [
" via the endoplasmic reticulum-Golgi intermediate complex (ERGIC), also known as vesicular-tubular cluster "
]
} | false |
4,507 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is a dominant negative inhibitor? | {
"answer_start": [
14082
],
"text": [
" dynamitin"
]
} | false |
4,508 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is dynamitin associated with? | {
"answer_start": [
14110
],
"text": [
"dynein-mediated transport"
]
} | false |
4,509 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is dynamitin associated with? | {
"answer_start": [
14136
],
"text": [
" reduced N's accumulation in the Golgi"
]
} | false |
4,510 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What does recent data indicate? | {
"answer_start": [
14426
],
"text": [
" that microtubular transport is indeed utilized for the New World hantavirus SNV"
]
} | false |
4,511 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | Why have Hantavirus diseases of man been suspected of having an immunopathogenic basis? | {
"answer_start": [
15425
],
"text": [
"plasma viral RNA with"
]
} | false |
4,542 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is a critical feature of both? | {
"answer_start": [
15723
],
"text": [
" a transient (~ 1-5 days) capillary leak involving the kidney and retroperitoneal space in HFRS and the lungs in HCPS"
]
} | false |
4,543 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is the character of he resulting leakage? | {
"answer_start": [
15864
],
"text": [
"is exudative in character, with chemical composition high in protein and resembling plasma."
]
} | false |
4,544 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | Which is an especially attractive candidate as an important in vivo receptor for hantaviruses? | {
"answer_start": [
16094
],
"text": [
" β3 integrin"
]
} | false |
4,545 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is the likely way that hantaviruses arrive at their target tissues? | {
"answer_start": [
16255
],
"text": [
"through uptake by regional lymph nodes, perhaps with or within an escorting lung histiocyte"
]
} | false |
4,546 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What does the virus seed? | {
"answer_start": [
16364
],
"text": [
"local endothelium"
]
} | false |
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