assay_context
large_stringclasses
4 values
assay_id
large_stringclasses
11 values
assay_objective
large_stringclasses
11 values
biosample
large_stringclasses
10 values
candidate_count
int64
10
10
candidates_json_path
large_stringlengths
76
76
cheap_gate_status
large_stringclasses
1 value
chromosome
large_stringclasses
9 values
gene
large_stringclasses
11 values
instruction_path
large_stringlengths
79
79
interface_mode
large_stringclasses
1 value
leakage_audit
bool
1 class
locus_id
large_stringclasses
11 values
objective
large_stringclasses
10 values
ontology_term
large_stringclasses
9 values
oracle_replay
bool
1 class
output
large_stringclasses
5 values
package_path
large_stringlengths
53
53
private_fields_absent
bool
1 class
public_evidence_channels
large_stringclasses
1 value
public_evidence_guide_path
large_stringlengths
87
87
public_support_audit
bool
1 class
reference_build
large_stringclasses
1 value
source_interval
large_stringclasses
11 values
subset
large_stringclasses
1 value
task_family
large_stringclasses
1 value
task_id
large_stringlengths
25
25
task_json_path
large_stringlengths
70
70
task_kind
large_stringclasses
1 value
wrong_answer_negative_control
bool
1 class
CAGE
cage_liver
prioritize promoter or enhancer edits affecting liver regulatory output
liver
10
latent_mining/biology/tasks/apsci_triage_018bc0230b40/solver/candidates.json
pass
chr1
PCSK9
latent_mining/biology/tasks/apsci_triage_018bc0230b40/tb_science/instruction.md
adversarial
true
pcsk9_liver
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in liver, using only public sequence and plausibility features.
UBERON:0002107
true
CAGE
latent_mining/biology/tasks/apsci_triage_018bc0230b40
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_018bc0230b40/solver/public_evidence_guide.json
true
hg38
chr1:55200000-55400000
biology
regulatory_variant_triage_cached
apsci_triage_018bc0230b40
latent_mining/biology/tasks/apsci_triage_018bc0230b40/solver/task.json
search
true
ChIP
chip_histone_a549
prioritize distal enhancer or super-enhancer edits in oncology regulatory context
A549 lung epithelial cancer cell line
10
latent_mining/biology/tasks/apsci_triage_01d843d085ed/solver/candidates.json
pass
chr8
MYC
latent_mining/biology/tasks/apsci_triage_01d843d085ed/tb_science/instruction.md
adversarial
true
myc_8q24
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in A549 lung epithelial cancer cell line, using only public sequence and plausibility features.
EFO:0001086
true
CHIP_HISTONE
latent_mining/biology/tasks/apsci_triage_01d843d085ed
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_01d843d085ed/solver/public_evidence_guide.json
true
hg38
chr8:127800000-128050000
biology
regulatory_variant_triage_cached
apsci_triage_01d843d085ed
latent_mining/biology/tasks/apsci_triage_01d843d085ed/solver/task.json
search
true
CAGE
cage_liver
prioritize promoter or enhancer edits affecting liver regulatory output
liver
10
latent_mining/biology/tasks/apsci_triage_034f4be4f75d/solver/candidates.json
pass
chr1
PCSK9
latent_mining/biology/tasks/apsci_triage_034f4be4f75d/tb_science/instruction.md
adversarial
true
pcsk9_liver
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in liver, using only public sequence and plausibility features.
UBERON:0002107
true
CAGE
latent_mining/biology/tasks/apsci_triage_034f4be4f75d
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_034f4be4f75d/solver/public_evidence_guide.json
true
hg38
chr1:55200000-55400000
biology
regulatory_variant_triage_cached
apsci_triage_034f4be4f75d
latent_mining/biology/tasks/apsci_triage_034f4be4f75d/solver/task.json
search
true
CAGE
cage_hela_s3
prioritize promoter-like edits affecting CAGE TSS regulatory output
HeLa-S3 cervical cancer cell line
10
latent_mining/biology/tasks/apsci_triage_038c54a1c801/solver/candidates.json
pass
chr5
TERT
latent_mining/biology/tasks/apsci_triage_038c54a1c801/tb_science/instruction.md
adversarial
true
tert_promoter
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in HeLa-S3 cervical cancer cell line, using only public sequence and plausibility features.
EFO:0002791
true
CAGE
latent_mining/biology/tasks/apsci_triage_038c54a1c801
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_038c54a1c801/solver/public_evidence_guide.json
true
hg38
chr5:1100000-1300000
biology
regulatory_variant_triage_cached
apsci_triage_038c54a1c801
latent_mining/biology/tasks/apsci_triage_038c54a1c801/solver/task.json
search
true
RNA_SEQ
rna_seq_small_intestine
prioritize intestinal enhancer edits affecting digestive regulatory output
small intestine
10
latent_mining/biology/tasks/apsci_triage_045d84e4ad43/solver/candidates.json
pass
chr2
LCT/MCM6
latent_mining/biology/tasks/apsci_triage_045d84e4ad43/tb_science/instruction.md
adversarial
true
lct_mcm6
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in small intestine, using only public sequence and plausibility features.
UBERON:0002108
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_045d84e4ad43
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_045d84e4ad43/solver/public_evidence_guide.json
true
hg38
chr2:136600000-136800000
biology
regulatory_variant_triage_cached
apsci_triage_045d84e4ad43
latent_mining/biology/tasks/apsci_triage_045d84e4ad43/solver/task.json
search
true
ATAC
atac_tcell
prioritize promoter or enhancer edits in T-cell immune-regulatory context
CD4/T cell
10
latent_mining/biology/tasks/apsci_triage_059b647310d2/solver/candidates.json
pass
chr10
IL2RA
latent_mining/biology/tasks/apsci_triage_059b647310d2/tb_science/instruction.md
adversarial
true
il2ra_tcell
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in CD4/T cell, using only public sequence and plausibility features.
CL:0000624
true
ATAC
latent_mining/biology/tasks/apsci_triage_059b647310d2
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_059b647310d2/solver/public_evidence_guide.json
true
hg38
chr10:6000000-6150000
biology
regulatory_variant_triage_cached
apsci_triage_059b647310d2
latent_mining/biology/tasks/apsci_triage_059b647310d2/solver/task.json
search
true
ATAC
atac_subcutaneous_adipose
prioritize distal enhancer edits in adipose regulatory context
subcutaneous adipose tissue
10
latent_mining/biology/tasks/apsci_triage_060ec3545056/solver/candidates.json
pass
chr16
FTO/IRX3
latent_mining/biology/tasks/apsci_triage_060ec3545056/tb_science/instruction.md
adversarial
true
fto_irx3_adipose
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in subcutaneous adipose tissue, using only public sequence and plausibility features.
UBERON:0002190
true
ATAC
latent_mining/biology/tasks/apsci_triage_060ec3545056
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_060ec3545056/solver/public_evidence_guide.json
true
hg38
chr16:53700000-53900000
biology
regulatory_variant_triage_cached
apsci_triage_060ec3545056
latent_mining/biology/tasks/apsci_triage_060ec3545056/solver/task.json
search
true
RNA_SEQ
rna_seq_beta_cell
prioritize beta-cell promoter or enhancer edits affecting endocrine RNA-seq regulatory output
type B pancreatic cell
10
latent_mining/biology/tasks/apsci_triage_098797bb3844/solver/candidates.json
pass
chr11
INS
latent_mining/biology/tasks/apsci_triage_098797bb3844/tb_science/instruction.md
adversarial
true
ins_islet
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in type B pancreatic cell, using only public sequence and plausibility features.
CL:0000169
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_098797bb3844
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_098797bb3844/solver/public_evidence_guide.json
true
hg38
chr11:2100000-2300000
biology
regulatory_variant_triage_cached
apsci_triage_098797bb3844
latent_mining/biology/tasks/apsci_triage_098797bb3844/solver/task.json
search
true
CAGE
cage_liver
prioritize promoter or enhancer edits affecting liver regulatory output
liver
10
latent_mining/biology/tasks/apsci_triage_0a6f8c4b683b/solver/candidates.json
pass
chr1
PCSK9
latent_mining/biology/tasks/apsci_triage_0a6f8c4b683b/tb_science/instruction.md
adversarial
true
pcsk9_liver
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in liver, using only public sequence and plausibility features.
UBERON:0002107
true
CAGE
latent_mining/biology/tasks/apsci_triage_0a6f8c4b683b
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_0a6f8c4b683b/solver/public_evidence_guide.json
true
hg38
chr1:55200000-55400000
biology
regulatory_variant_triage_cached
apsci_triage_0a6f8c4b683b
latent_mining/biology/tasks/apsci_triage_0a6f8c4b683b/solver/task.json
search
true
RNA_SEQ
rna_seq_small_intestine
prioritize intestinal enhancer edits affecting digestive regulatory output
small intestine
10
latent_mining/biology/tasks/apsci_triage_0acaba7a7df6/solver/candidates.json
pass
chr2
LCT/MCM6
latent_mining/biology/tasks/apsci_triage_0acaba7a7df6/tb_science/instruction.md
adversarial
true
lct_mcm6
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in small intestine, using only public sequence and plausibility features.
UBERON:0002108
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_0acaba7a7df6
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_0acaba7a7df6/solver/public_evidence_guide.json
true
hg38
chr2:136600000-136800000
biology
regulatory_variant_triage_cached
apsci_triage_0acaba7a7df6
latent_mining/biology/tasks/apsci_triage_0acaba7a7df6/solver/task.json
search
true
ChIP
chip_histone_a549
prioritize distal enhancer or super-enhancer edits in oncology regulatory context
A549 lung epithelial cancer cell line
10
latent_mining/biology/tasks/apsci_triage_0b1b652d7c4f/solver/candidates.json
pass
chr8
MYC
latent_mining/biology/tasks/apsci_triage_0b1b652d7c4f/tb_science/instruction.md
adversarial
true
myc_8q24
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in A549 lung epithelial cancer cell line, using only public sequence and plausibility features.
EFO:0001086
true
CHIP_HISTONE
latent_mining/biology/tasks/apsci_triage_0b1b652d7c4f
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_0b1b652d7c4f/solver/public_evidence_guide.json
true
hg38
chr8:127800000-128050000
biology
regulatory_variant_triage_cached
apsci_triage_0b1b652d7c4f
latent_mining/biology/tasks/apsci_triage_0b1b652d7c4f/solver/task.json
search
true
CAGE
cage_liver
prioritize promoter or enhancer edits affecting liver regulatory output
liver
10
latent_mining/biology/tasks/apsci_triage_0b6ecd452509/solver/candidates.json
pass
chr1
PCSK9
latent_mining/biology/tasks/apsci_triage_0b6ecd452509/tb_science/instruction.md
adversarial
true
pcsk9_liver
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in liver, using only public sequence and plausibility features.
UBERON:0002107
true
CAGE
latent_mining/biology/tasks/apsci_triage_0b6ecd452509
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_0b6ecd452509/solver/public_evidence_guide.json
true
hg38
chr1:55200000-55400000
biology
regulatory_variant_triage_cached
apsci_triage_0b6ecd452509
latent_mining/biology/tasks/apsci_triage_0b6ecd452509/solver/task.json
search
true
CAGE
cage_hela_s3
prioritize promoter-like edits affecting CAGE TSS regulatory output
HeLa-S3 cervical cancer cell line
10
latent_mining/biology/tasks/apsci_triage_0b8d82104da5/solver/candidates.json
pass
chr5
TERT
latent_mining/biology/tasks/apsci_triage_0b8d82104da5/tb_science/instruction.md
adversarial
true
tert_promoter
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in HeLa-S3 cervical cancer cell line, using only public sequence and plausibility features.
EFO:0002791
true
CAGE
latent_mining/biology/tasks/apsci_triage_0b8d82104da5
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_0b8d82104da5/solver/public_evidence_guide.json
true
hg38
chr5:1100000-1300000
biology
regulatory_variant_triage_cached
apsci_triage_0b8d82104da5
latent_mining/biology/tasks/apsci_triage_0b8d82104da5/solver/task.json
search
true
ChIP
chip_erythroblast_tf
prioritize TF-bound enhancer edits affecting erythroid hemoglobin-switching regulatory output
erythroblast
10
latent_mining/biology/tasks/apsci_triage_0ca4f2d706cd/solver/candidates.json
pass
chr2
BCL11A
latent_mining/biology/tasks/apsci_triage_0ca4f2d706cd/tb_science/instruction.md
adversarial
true
bcl11a_erythroid
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_0ca4f2d706cd
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_0ca4f2d706cd/solver/public_evidence_guide.json
true
hg38
chr2:60500000-60800000
biology
regulatory_variant_triage_cached
apsci_triage_0ca4f2d706cd
latent_mining/biology/tasks/apsci_triage_0ca4f2d706cd/solver/task.json
search
true
ChIP
chip_erythroblast_tf
prioritize TF-bound enhancer edits affecting erythroid hemoglobin-switching regulatory output
erythroblast
10
latent_mining/biology/tasks/apsci_triage_0d05cc727176/solver/candidates.json
pass
chr2
BCL11A
latent_mining/biology/tasks/apsci_triage_0d05cc727176/tb_science/instruction.md
adversarial
true
bcl11a_erythroid
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_0d05cc727176
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_0d05cc727176/solver/public_evidence_guide.json
true
hg38
chr2:60500000-60800000
biology
regulatory_variant_triage_cached
apsci_triage_0d05cc727176
latent_mining/biology/tasks/apsci_triage_0d05cc727176/solver/task.json
search
true
ATAC
atac_subcutaneous_adipose
prioritize distal enhancer edits in adipose regulatory context
subcutaneous adipose tissue
10
latent_mining/biology/tasks/apsci_triage_0da6ab2d8cf0/solver/candidates.json
pass
chr16
FTO/IRX3
latent_mining/biology/tasks/apsci_triage_0da6ab2d8cf0/tb_science/instruction.md
adversarial
true
fto_irx3_adipose
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in subcutaneous adipose tissue, using only public sequence and plausibility features.
UBERON:0002190
true
ATAC
latent_mining/biology/tasks/apsci_triage_0da6ab2d8cf0
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_0da6ab2d8cf0/solver/public_evidence_guide.json
true
hg38
chr16:53700000-53900000
biology
regulatory_variant_triage_cached
apsci_triage_0da6ab2d8cf0
latent_mining/biology/tasks/apsci_triage_0da6ab2d8cf0/solver/task.json
search
true
CAGE
cage_hela_s3
prioritize promoter-like edits affecting CAGE TSS regulatory output
HeLa-S3 cervical cancer cell line
10
latent_mining/biology/tasks/apsci_triage_0f196e892e53/solver/candidates.json
pass
chr5
TERT
latent_mining/biology/tasks/apsci_triage_0f196e892e53/tb_science/instruction.md
adversarial
true
tert_promoter
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in HeLa-S3 cervical cancer cell line, using only public sequence and plausibility features.
EFO:0002791
true
CAGE
latent_mining/biology/tasks/apsci_triage_0f196e892e53
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_0f196e892e53/solver/public_evidence_guide.json
true
hg38
chr5:1100000-1300000
biology
regulatory_variant_triage_cached
apsci_triage_0f196e892e53
latent_mining/biology/tasks/apsci_triage_0f196e892e53/solver/task.json
search
true
ChIP
chip_erythroid_tf
prioritize TF-bound promoter/enhancer edits in erythroid or megakaryocytic context
erythroid/megakaryocytic
10
latent_mining/biology/tasks/apsci_triage_148fac15d81c/solver/candidates.json
pass
chrX
GATA1
latent_mining/biology/tasks/apsci_triage_148fac15d81c/tb_science/instruction.md
adversarial
true
gata1_chrx
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroid/megakaryocytic, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_148fac15d81c
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_148fac15d81c/solver/public_evidence_guide.json
true
hg38
chrX:48500000-48700000
biology
regulatory_variant_triage_cached
apsci_triage_148fac15d81c
latent_mining/biology/tasks/apsci_triage_148fac15d81c/solver/task.json
search
true
CAGE
cage_hela_s3
prioritize promoter-like edits affecting CAGE TSS regulatory output
HeLa-S3 cervical cancer cell line
10
latent_mining/biology/tasks/apsci_triage_190c3a75b807/solver/candidates.json
pass
chr5
TERT
latent_mining/biology/tasks/apsci_triage_190c3a75b807/tb_science/instruction.md
adversarial
true
tert_promoter
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in HeLa-S3 cervical cancer cell line, using only public sequence and plausibility features.
EFO:0002791
true
CAGE
latent_mining/biology/tasks/apsci_triage_190c3a75b807
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_190c3a75b807/solver/public_evidence_guide.json
true
hg38
chr5:1100000-1300000
biology
regulatory_variant_triage_cached
apsci_triage_190c3a75b807
latent_mining/biology/tasks/apsci_triage_190c3a75b807/solver/task.json
search
true
CAGE
cage_hela_s3
prioritize promoter-like edits affecting CAGE TSS regulatory output
HeLa-S3 cervical cancer cell line
10
latent_mining/biology/tasks/apsci_triage_1a4a51ce41f6/solver/candidates.json
pass
chr5
TERT
latent_mining/biology/tasks/apsci_triage_1a4a51ce41f6/tb_science/instruction.md
adversarial
true
tert_promoter
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in HeLa-S3 cervical cancer cell line, using only public sequence and plausibility features.
EFO:0002791
true
CAGE
latent_mining/biology/tasks/apsci_triage_1a4a51ce41f6
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_1a4a51ce41f6/solver/public_evidence_guide.json
true
hg38
chr5:1100000-1300000
biology
regulatory_variant_triage_cached
apsci_triage_1a4a51ce41f6
latent_mining/biology/tasks/apsci_triage_1a4a51ce41f6/solver/task.json
search
true
ChIP
chip_erythroblast_lcr_tf
prioritize TF-bound locus-control-region enhancer edits in erythroblast regulatory context
erythroblast
10
latent_mining/biology/tasks/apsci_triage_1ded69978d25/solver/candidates.json
pass
chr11
HBB/HBE
latent_mining/biology/tasks/apsci_triage_1ded69978d25/tb_science/instruction.md
adversarial
true
hbb_lcr
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_1ded69978d25
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_1ded69978d25/solver/public_evidence_guide.json
true
hg38
chr11:5200000-5300000
biology
regulatory_variant_triage_cached
apsci_triage_1ded69978d25
latent_mining/biology/tasks/apsci_triage_1ded69978d25/solver/task.json
search
true
RNA_SEQ
rna_seq_beta_cell
prioritize beta-cell promoter or enhancer edits affecting endocrine RNA-seq regulatory output
type B pancreatic cell
10
latent_mining/biology/tasks/apsci_triage_1f18d39dcc00/solver/candidates.json
pass
chr11
INS
latent_mining/biology/tasks/apsci_triage_1f18d39dcc00/tb_science/instruction.md
adversarial
true
ins_islet
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in type B pancreatic cell, using only public sequence and plausibility features.
CL:0000169
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_1f18d39dcc00
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_1f18d39dcc00/solver/public_evidence_guide.json
true
hg38
chr11:2100000-2300000
biology
regulatory_variant_triage_cached
apsci_triage_1f18d39dcc00
latent_mining/biology/tasks/apsci_triage_1f18d39dcc00/solver/task.json
search
true
RNA_SEQ
rna_seq_airway_epithelial
prioritize airway epithelial promoter or enhancer edits affecting RNA-seq regulatory output
airway epithelial cell
10
latent_mining/biology/tasks/apsci_triage_1fc12cd15415/solver/candidates.json
pass
chr7
CFTR
latent_mining/biology/tasks/apsci_triage_1fc12cd15415/tb_science/instruction.md
adversarial
true
cftr_epithelial
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in airway epithelial cell, using only public sequence and plausibility features.
CL:0002368
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_1fc12cd15415
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_1fc12cd15415/solver/public_evidence_guide.json
true
hg38
chr7:117500000-117700000
biology
regulatory_variant_triage_cached
apsci_triage_1fc12cd15415
latent_mining/biology/tasks/apsci_triage_1fc12cd15415/solver/task.json
search
true
RNA_SEQ
rna_seq_beta_cell
prioritize beta-cell promoter or enhancer edits affecting endocrine RNA-seq regulatory output
type B pancreatic cell
10
latent_mining/biology/tasks/apsci_triage_22d582c8efaf/solver/candidates.json
pass
chr11
INS
latent_mining/biology/tasks/apsci_triage_22d582c8efaf/tb_science/instruction.md
adversarial
true
ins_islet
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in type B pancreatic cell, using only public sequence and plausibility features.
CL:0000169
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_22d582c8efaf
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_22d582c8efaf/solver/public_evidence_guide.json
true
hg38
chr11:2100000-2300000
biology
regulatory_variant_triage_cached
apsci_triage_22d582c8efaf
latent_mining/biology/tasks/apsci_triage_22d582c8efaf/solver/task.json
search
true
ATAC
atac_subcutaneous_adipose
prioritize distal enhancer edits in adipose regulatory context
subcutaneous adipose tissue
10
latent_mining/biology/tasks/apsci_triage_238881b9c961/solver/candidates.json
pass
chr16
FTO/IRX3
latent_mining/biology/tasks/apsci_triage_238881b9c961/tb_science/instruction.md
adversarial
true
fto_irx3_adipose
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in subcutaneous adipose tissue, using only public sequence and plausibility features.
UBERON:0002190
true
ATAC
latent_mining/biology/tasks/apsci_triage_238881b9c961
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_238881b9c961/solver/public_evidence_guide.json
true
hg38
chr16:53700000-53900000
biology
regulatory_variant_triage_cached
apsci_triage_238881b9c961
latent_mining/biology/tasks/apsci_triage_238881b9c961/solver/task.json
search
true
RNA_SEQ
rna_seq_small_intestine
prioritize intestinal enhancer edits affecting digestive regulatory output
small intestine
10
latent_mining/biology/tasks/apsci_triage_23ae7052234a/solver/candidates.json
pass
chr2
LCT/MCM6
latent_mining/biology/tasks/apsci_triage_23ae7052234a/tb_science/instruction.md
adversarial
true
lct_mcm6
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in small intestine, using only public sequence and plausibility features.
UBERON:0002108
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_23ae7052234a
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_23ae7052234a/solver/public_evidence_guide.json
true
hg38
chr2:136600000-136800000
biology
regulatory_variant_triage_cached
apsci_triage_23ae7052234a
latent_mining/biology/tasks/apsci_triage_23ae7052234a/solver/task.json
search
true
ChIP
chip_erythroblast_tf
prioritize TF-bound enhancer edits affecting erythroid hemoglobin-switching regulatory output
erythroblast
10
latent_mining/biology/tasks/apsci_triage_24623c135fbe/solver/candidates.json
pass
chr2
BCL11A
latent_mining/biology/tasks/apsci_triage_24623c135fbe/tb_science/instruction.md
adversarial
true
bcl11a_erythroid
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_24623c135fbe
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_24623c135fbe/solver/public_evidence_guide.json
true
hg38
chr2:60500000-60800000
biology
regulatory_variant_triage_cached
apsci_triage_24623c135fbe
latent_mining/biology/tasks/apsci_triage_24623c135fbe/solver/task.json
search
true
CAGE
cage_hela_s3
prioritize promoter-like edits affecting CAGE TSS regulatory output
HeLa-S3 cervical cancer cell line
10
latent_mining/biology/tasks/apsci_triage_26262170e717/solver/candidates.json
pass
chr5
TERT
latent_mining/biology/tasks/apsci_triage_26262170e717/tb_science/instruction.md
adversarial
true
tert_promoter
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in HeLa-S3 cervical cancer cell line, using only public sequence and plausibility features.
EFO:0002791
true
CAGE
latent_mining/biology/tasks/apsci_triage_26262170e717
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_26262170e717/solver/public_evidence_guide.json
true
hg38
chr5:1100000-1300000
biology
regulatory_variant_triage_cached
apsci_triage_26262170e717
latent_mining/biology/tasks/apsci_triage_26262170e717/solver/task.json
search
true
RNA_SEQ
rna_seq_airway_epithelial
prioritize airway epithelial promoter or enhancer edits affecting RNA-seq regulatory output
airway epithelial cell
10
latent_mining/biology/tasks/apsci_triage_27668c2e049d/solver/candidates.json
pass
chr7
CFTR
latent_mining/biology/tasks/apsci_triage_27668c2e049d/tb_science/instruction.md
adversarial
true
cftr_epithelial
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in airway epithelial cell, using only public sequence and plausibility features.
CL:0002368
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_27668c2e049d
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_27668c2e049d/solver/public_evidence_guide.json
true
hg38
chr7:117500000-117700000
biology
regulatory_variant_triage_cached
apsci_triage_27668c2e049d
latent_mining/biology/tasks/apsci_triage_27668c2e049d/solver/task.json
search
true
ChIP
chip_erythroblast_lcr_tf
prioritize TF-bound locus-control-region enhancer edits in erythroblast regulatory context
erythroblast
10
latent_mining/biology/tasks/apsci_triage_283da1e2c928/solver/candidates.json
pass
chr11
HBB/HBE
latent_mining/biology/tasks/apsci_triage_283da1e2c928/tb_science/instruction.md
adversarial
true
hbb_lcr
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_283da1e2c928
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_283da1e2c928/solver/public_evidence_guide.json
true
hg38
chr11:5200000-5300000
biology
regulatory_variant_triage_cached
apsci_triage_283da1e2c928
latent_mining/biology/tasks/apsci_triage_283da1e2c928/solver/task.json
search
true
ATAC
atac_subcutaneous_adipose
prioritize distal enhancer edits in adipose regulatory context
subcutaneous adipose tissue
10
latent_mining/biology/tasks/apsci_triage_2cb79fea6982/solver/candidates.json
pass
chr16
FTO/IRX3
latent_mining/biology/tasks/apsci_triage_2cb79fea6982/tb_science/instruction.md
adversarial
true
fto_irx3_adipose
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in subcutaneous adipose tissue, using only public sequence and plausibility features.
UBERON:0002190
true
ATAC
latent_mining/biology/tasks/apsci_triage_2cb79fea6982
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_2cb79fea6982/solver/public_evidence_guide.json
true
hg38
chr16:53700000-53900000
biology
regulatory_variant_triage_cached
apsci_triage_2cb79fea6982
latent_mining/biology/tasks/apsci_triage_2cb79fea6982/solver/task.json
search
true
ChIP
chip_erythroblast_tf
prioritize TF-bound enhancer edits affecting erythroid hemoglobin-switching regulatory output
erythroblast
10
latent_mining/biology/tasks/apsci_triage_2d34678e7412/solver/candidates.json
pass
chr2
BCL11A
latent_mining/biology/tasks/apsci_triage_2d34678e7412/tb_science/instruction.md
adversarial
true
bcl11a_erythroid
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_2d34678e7412
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_2d34678e7412/solver/public_evidence_guide.json
true
hg38
chr2:60500000-60800000
biology
regulatory_variant_triage_cached
apsci_triage_2d34678e7412
latent_mining/biology/tasks/apsci_triage_2d34678e7412/solver/task.json
search
true
ChIP
chip_erythroblast_lcr_tf
prioritize TF-bound locus-control-region enhancer edits in erythroblast regulatory context
erythroblast
10
latent_mining/biology/tasks/apsci_triage_2ed7eaf36182/solver/candidates.json
pass
chr11
HBB/HBE
latent_mining/biology/tasks/apsci_triage_2ed7eaf36182/tb_science/instruction.md
adversarial
true
hbb_lcr
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_2ed7eaf36182
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_2ed7eaf36182/solver/public_evidence_guide.json
true
hg38
chr11:5200000-5300000
biology
regulatory_variant_triage_cached
apsci_triage_2ed7eaf36182
latent_mining/biology/tasks/apsci_triage_2ed7eaf36182/solver/task.json
search
true
RNA_SEQ
rna_seq_small_intestine
prioritize intestinal enhancer edits affecting digestive regulatory output
small intestine
10
latent_mining/biology/tasks/apsci_triage_30e1ec35b83d/solver/candidates.json
pass
chr2
LCT/MCM6
latent_mining/biology/tasks/apsci_triage_30e1ec35b83d/tb_science/instruction.md
adversarial
true
lct_mcm6
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in small intestine, using only public sequence and plausibility features.
UBERON:0002108
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_30e1ec35b83d
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_30e1ec35b83d/solver/public_evidence_guide.json
true
hg38
chr2:136600000-136800000
biology
regulatory_variant_triage_cached
apsci_triage_30e1ec35b83d
latent_mining/biology/tasks/apsci_triage_30e1ec35b83d/solver/task.json
search
true
RNA_SEQ
rna_seq_airway_epithelial
prioritize airway epithelial promoter or enhancer edits affecting RNA-seq regulatory output
airway epithelial cell
10
latent_mining/biology/tasks/apsci_triage_30fdb0c7db5b/solver/candidates.json
pass
chr7
CFTR
latent_mining/biology/tasks/apsci_triage_30fdb0c7db5b/tb_science/instruction.md
adversarial
true
cftr_epithelial
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in airway epithelial cell, using only public sequence and plausibility features.
CL:0002368
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_30fdb0c7db5b
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_30fdb0c7db5b/solver/public_evidence_guide.json
true
hg38
chr7:117500000-117700000
biology
regulatory_variant_triage_cached
apsci_triage_30fdb0c7db5b
latent_mining/biology/tasks/apsci_triage_30fdb0c7db5b/solver/task.json
search
true
ATAC
atac_tcell
prioritize promoter or enhancer edits in T-cell immune-regulatory context
CD4/T cell
10
latent_mining/biology/tasks/apsci_triage_31e280d77332/solver/candidates.json
pass
chr10
IL2RA
latent_mining/biology/tasks/apsci_triage_31e280d77332/tb_science/instruction.md
adversarial
true
il2ra_tcell
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in CD4/T cell, using only public sequence and plausibility features.
CL:0000624
true
ATAC
latent_mining/biology/tasks/apsci_triage_31e280d77332
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_31e280d77332/solver/public_evidence_guide.json
true
hg38
chr10:6000000-6150000
biology
regulatory_variant_triage_cached
apsci_triage_31e280d77332
latent_mining/biology/tasks/apsci_triage_31e280d77332/solver/task.json
search
true
CAGE
cage_hela_s3
prioritize promoter-like edits affecting CAGE TSS regulatory output
HeLa-S3 cervical cancer cell line
10
latent_mining/biology/tasks/apsci_triage_349cdeee1532/solver/candidates.json
pass
chr5
TERT
latent_mining/biology/tasks/apsci_triage_349cdeee1532/tb_science/instruction.md
adversarial
true
tert_promoter
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in HeLa-S3 cervical cancer cell line, using only public sequence and plausibility features.
EFO:0002791
true
CAGE
latent_mining/biology/tasks/apsci_triage_349cdeee1532
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_349cdeee1532/solver/public_evidence_guide.json
true
hg38
chr5:1100000-1300000
biology
regulatory_variant_triage_cached
apsci_triage_349cdeee1532
latent_mining/biology/tasks/apsci_triage_349cdeee1532/solver/task.json
search
true
ChIP
chip_erythroblast_lcr_tf
prioritize TF-bound locus-control-region enhancer edits in erythroblast regulatory context
erythroblast
10
latent_mining/biology/tasks/apsci_triage_35393fadc21f/solver/candidates.json
pass
chr11
HBB/HBE
latent_mining/biology/tasks/apsci_triage_35393fadc21f/tb_science/instruction.md
adversarial
true
hbb_lcr
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_35393fadc21f
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_35393fadc21f/solver/public_evidence_guide.json
true
hg38
chr11:5200000-5300000
biology
regulatory_variant_triage_cached
apsci_triage_35393fadc21f
latent_mining/biology/tasks/apsci_triage_35393fadc21f/solver/task.json
search
true
ATAC
atac_tcell
prioritize promoter or enhancer edits in T-cell immune-regulatory context
CD4/T cell
10
latent_mining/biology/tasks/apsci_triage_3751f6faa8e6/solver/candidates.json
pass
chr10
IL2RA
latent_mining/biology/tasks/apsci_triage_3751f6faa8e6/tb_science/instruction.md
adversarial
true
il2ra_tcell
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in CD4/T cell, using only public sequence and plausibility features.
CL:0000624
true
ATAC
latent_mining/biology/tasks/apsci_triage_3751f6faa8e6
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_3751f6faa8e6/solver/public_evidence_guide.json
true
hg38
chr10:6000000-6150000
biology
regulatory_variant_triage_cached
apsci_triage_3751f6faa8e6
latent_mining/biology/tasks/apsci_triage_3751f6faa8e6/solver/task.json
search
true
RNA_SEQ
rna_seq_airway_epithelial
prioritize airway epithelial promoter or enhancer edits affecting RNA-seq regulatory output
airway epithelial cell
10
latent_mining/biology/tasks/apsci_triage_380f0dc939d3/solver/candidates.json
pass
chr7
CFTR
latent_mining/biology/tasks/apsci_triage_380f0dc939d3/tb_science/instruction.md
adversarial
true
cftr_epithelial
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in airway epithelial cell, using only public sequence and plausibility features.
CL:0002368
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_380f0dc939d3
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_380f0dc939d3/solver/public_evidence_guide.json
true
hg38
chr7:117500000-117700000
biology
regulatory_variant_triage_cached
apsci_triage_380f0dc939d3
latent_mining/biology/tasks/apsci_triage_380f0dc939d3/solver/task.json
search
true
ATAC
atac_subcutaneous_adipose
prioritize distal enhancer edits in adipose regulatory context
subcutaneous adipose tissue
10
latent_mining/biology/tasks/apsci_triage_39c6dd97a117/solver/candidates.json
pass
chr16
FTO/IRX3
latent_mining/biology/tasks/apsci_triage_39c6dd97a117/tb_science/instruction.md
adversarial
true
fto_irx3_adipose
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in subcutaneous adipose tissue, using only public sequence and plausibility features.
UBERON:0002190
true
ATAC
latent_mining/biology/tasks/apsci_triage_39c6dd97a117
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_39c6dd97a117/solver/public_evidence_guide.json
true
hg38
chr16:53700000-53900000
biology
regulatory_variant_triage_cached
apsci_triage_39c6dd97a117
latent_mining/biology/tasks/apsci_triage_39c6dd97a117/solver/task.json
search
true
RNA_SEQ
rna_seq_small_intestine
prioritize intestinal enhancer edits affecting digestive regulatory output
small intestine
10
latent_mining/biology/tasks/apsci_triage_431fa109e926/solver/candidates.json
pass
chr2
LCT/MCM6
latent_mining/biology/tasks/apsci_triage_431fa109e926/tb_science/instruction.md
adversarial
true
lct_mcm6
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in small intestine, using only public sequence and plausibility features.
UBERON:0002108
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_431fa109e926
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_431fa109e926/solver/public_evidence_guide.json
true
hg38
chr2:136600000-136800000
biology
regulatory_variant_triage_cached
apsci_triage_431fa109e926
latent_mining/biology/tasks/apsci_triage_431fa109e926/solver/task.json
search
true
ChIP
chip_histone_a549
prioritize distal enhancer or super-enhancer edits in oncology regulatory context
A549 lung epithelial cancer cell line
10
latent_mining/biology/tasks/apsci_triage_4866137c529f/solver/candidates.json
pass
chr8
MYC
latent_mining/biology/tasks/apsci_triage_4866137c529f/tb_science/instruction.md
adversarial
true
myc_8q24
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in A549 lung epithelial cancer cell line, using only public sequence and plausibility features.
EFO:0001086
true
CHIP_HISTONE
latent_mining/biology/tasks/apsci_triage_4866137c529f
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_4866137c529f/solver/public_evidence_guide.json
true
hg38
chr8:127800000-128050000
biology
regulatory_variant_triage_cached
apsci_triage_4866137c529f
latent_mining/biology/tasks/apsci_triage_4866137c529f/solver/task.json
search
true
ChIP
chip_erythroblast_lcr_tf
prioritize TF-bound locus-control-region enhancer edits in erythroblast regulatory context
erythroblast
10
latent_mining/biology/tasks/apsci_triage_497bc4b77fbd/solver/candidates.json
pass
chr11
HBB/HBE
latent_mining/biology/tasks/apsci_triage_497bc4b77fbd/tb_science/instruction.md
adversarial
true
hbb_lcr
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_497bc4b77fbd
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_497bc4b77fbd/solver/public_evidence_guide.json
true
hg38
chr11:5200000-5300000
biology
regulatory_variant_triage_cached
apsci_triage_497bc4b77fbd
latent_mining/biology/tasks/apsci_triage_497bc4b77fbd/solver/task.json
search
true
ATAC
atac_tcell
prioritize promoter or enhancer edits in T-cell immune-regulatory context
CD4/T cell
10
latent_mining/biology/tasks/apsci_triage_4bdcbf0d0e58/solver/candidates.json
pass
chr10
IL2RA
latent_mining/biology/tasks/apsci_triage_4bdcbf0d0e58/tb_science/instruction.md
adversarial
true
il2ra_tcell
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in CD4/T cell, using only public sequence and plausibility features.
CL:0000624
true
ATAC
latent_mining/biology/tasks/apsci_triage_4bdcbf0d0e58
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_4bdcbf0d0e58/solver/public_evidence_guide.json
true
hg38
chr10:6000000-6150000
biology
regulatory_variant_triage_cached
apsci_triage_4bdcbf0d0e58
latent_mining/biology/tasks/apsci_triage_4bdcbf0d0e58/solver/task.json
search
true
CAGE
cage_liver
prioritize promoter or enhancer edits affecting liver regulatory output
liver
10
latent_mining/biology/tasks/apsci_triage_4c13ac4d079e/solver/candidates.json
pass
chr1
PCSK9
latent_mining/biology/tasks/apsci_triage_4c13ac4d079e/tb_science/instruction.md
adversarial
true
pcsk9_liver
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in liver, using only public sequence and plausibility features.
UBERON:0002107
true
CAGE
latent_mining/biology/tasks/apsci_triage_4c13ac4d079e
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_4c13ac4d079e/solver/public_evidence_guide.json
true
hg38
chr1:55200000-55400000
biology
regulatory_variant_triage_cached
apsci_triage_4c13ac4d079e
latent_mining/biology/tasks/apsci_triage_4c13ac4d079e/solver/task.json
search
true
ChIP
chip_erythroblast_tf
prioritize TF-bound enhancer edits affecting erythroid hemoglobin-switching regulatory output
erythroblast
10
latent_mining/biology/tasks/apsci_triage_4eb2be129d3f/solver/candidates.json
pass
chr2
BCL11A
latent_mining/biology/tasks/apsci_triage_4eb2be129d3f/tb_science/instruction.md
adversarial
true
bcl11a_erythroid
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_4eb2be129d3f
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_4eb2be129d3f/solver/public_evidence_guide.json
true
hg38
chr2:60500000-60800000
biology
regulatory_variant_triage_cached
apsci_triage_4eb2be129d3f
latent_mining/biology/tasks/apsci_triage_4eb2be129d3f/solver/task.json
search
true
ChIP
chip_erythroblast_tf
prioritize TF-bound enhancer edits affecting erythroid hemoglobin-switching regulatory output
erythroblast
10
latent_mining/biology/tasks/apsci_triage_4fcbc1adbce5/solver/candidates.json
pass
chr2
BCL11A
latent_mining/biology/tasks/apsci_triage_4fcbc1adbce5/tb_science/instruction.md
adversarial
true
bcl11a_erythroid
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_4fcbc1adbce5
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_4fcbc1adbce5/solver/public_evidence_guide.json
true
hg38
chr2:60500000-60800000
biology
regulatory_variant_triage_cached
apsci_triage_4fcbc1adbce5
latent_mining/biology/tasks/apsci_triage_4fcbc1adbce5/solver/task.json
search
true
ChIP
chip_erythroid_tf
prioritize TF-bound promoter/enhancer edits in erythroid or megakaryocytic context
erythroid/megakaryocytic
10
latent_mining/biology/tasks/apsci_triage_51a4caf9f4fc/solver/candidates.json
pass
chrX
GATA1
latent_mining/biology/tasks/apsci_triage_51a4caf9f4fc/tb_science/instruction.md
adversarial
true
gata1_chrx
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroid/megakaryocytic, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_51a4caf9f4fc
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_51a4caf9f4fc/solver/public_evidence_guide.json
true
hg38
chrX:48500000-48700000
biology
regulatory_variant_triage_cached
apsci_triage_51a4caf9f4fc
latent_mining/biology/tasks/apsci_triage_51a4caf9f4fc/solver/task.json
search
true
ChIP
chip_erythroid_tf
prioritize TF-bound promoter/enhancer edits in erythroid or megakaryocytic context
erythroid/megakaryocytic
10
latent_mining/biology/tasks/apsci_triage_522442c37908/solver/candidates.json
pass
chrX
GATA1
latent_mining/biology/tasks/apsci_triage_522442c37908/tb_science/instruction.md
adversarial
true
gata1_chrx
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroid/megakaryocytic, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_522442c37908
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_522442c37908/solver/public_evidence_guide.json
true
hg38
chrX:48500000-48700000
biology
regulatory_variant_triage_cached
apsci_triage_522442c37908
latent_mining/biology/tasks/apsci_triage_522442c37908/solver/task.json
search
true
CAGE
cage_hela_s3
prioritize promoter-like edits affecting CAGE TSS regulatory output
HeLa-S3 cervical cancer cell line
10
latent_mining/biology/tasks/apsci_triage_52a393b85246/solver/candidates.json
pass
chr5
TERT
latent_mining/biology/tasks/apsci_triage_52a393b85246/tb_science/instruction.md
adversarial
true
tert_promoter
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in HeLa-S3 cervical cancer cell line, using only public sequence and plausibility features.
EFO:0002791
true
CAGE
latent_mining/biology/tasks/apsci_triage_52a393b85246
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_52a393b85246/solver/public_evidence_guide.json
true
hg38
chr5:1100000-1300000
biology
regulatory_variant_triage_cached
apsci_triage_52a393b85246
latent_mining/biology/tasks/apsci_triage_52a393b85246/solver/task.json
search
true
RNA_SEQ
rna_seq_beta_cell
prioritize beta-cell promoter or enhancer edits affecting endocrine RNA-seq regulatory output
type B pancreatic cell
10
latent_mining/biology/tasks/apsci_triage_54cd4b6b2284/solver/candidates.json
pass
chr11
INS
latent_mining/biology/tasks/apsci_triage_54cd4b6b2284/tb_science/instruction.md
adversarial
true
ins_islet
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in type B pancreatic cell, using only public sequence and plausibility features.
CL:0000169
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_54cd4b6b2284
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_54cd4b6b2284/solver/public_evidence_guide.json
true
hg38
chr11:2100000-2300000
biology
regulatory_variant_triage_cached
apsci_triage_54cd4b6b2284
latent_mining/biology/tasks/apsci_triage_54cd4b6b2284/solver/task.json
search
true
ChIP
chip_erythroid_tf
prioritize TF-bound promoter/enhancer edits in erythroid or megakaryocytic context
erythroid/megakaryocytic
10
latent_mining/biology/tasks/apsci_triage_55fedb382f5f/solver/candidates.json
pass
chrX
GATA1
latent_mining/biology/tasks/apsci_triage_55fedb382f5f/tb_science/instruction.md
adversarial
true
gata1_chrx
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroid/megakaryocytic, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_55fedb382f5f
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_55fedb382f5f/solver/public_evidence_guide.json
true
hg38
chrX:48500000-48700000
biology
regulatory_variant_triage_cached
apsci_triage_55fedb382f5f
latent_mining/biology/tasks/apsci_triage_55fedb382f5f/solver/task.json
search
true
ChIP
chip_erythroblast_lcr_tf
prioritize TF-bound locus-control-region enhancer edits in erythroblast regulatory context
erythroblast
10
latent_mining/biology/tasks/apsci_triage_5988b4ad6b90/solver/candidates.json
pass
chr11
HBB/HBE
latent_mining/biology/tasks/apsci_triage_5988b4ad6b90/tb_science/instruction.md
adversarial
true
hbb_lcr
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_5988b4ad6b90
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_5988b4ad6b90/solver/public_evidence_guide.json
true
hg38
chr11:5200000-5300000
biology
regulatory_variant_triage_cached
apsci_triage_5988b4ad6b90
latent_mining/biology/tasks/apsci_triage_5988b4ad6b90/solver/task.json
search
true
ATAC
atac_subcutaneous_adipose
prioritize distal enhancer edits in adipose regulatory context
subcutaneous adipose tissue
10
latent_mining/biology/tasks/apsci_triage_5a044d544833/solver/candidates.json
pass
chr16
FTO/IRX3
latent_mining/biology/tasks/apsci_triage_5a044d544833/tb_science/instruction.md
adversarial
true
fto_irx3_adipose
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in subcutaneous adipose tissue, using only public sequence and plausibility features.
UBERON:0002190
true
ATAC
latent_mining/biology/tasks/apsci_triage_5a044d544833
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_5a044d544833/solver/public_evidence_guide.json
true
hg38
chr16:53700000-53900000
biology
regulatory_variant_triage_cached
apsci_triage_5a044d544833
latent_mining/biology/tasks/apsci_triage_5a044d544833/solver/task.json
search
true
CAGE
cage_hela_s3
prioritize promoter-like edits affecting CAGE TSS regulatory output
HeLa-S3 cervical cancer cell line
10
latent_mining/biology/tasks/apsci_triage_5b0afc0e692c/solver/candidates.json
pass
chr5
TERT
latent_mining/biology/tasks/apsci_triage_5b0afc0e692c/tb_science/instruction.md
adversarial
true
tert_promoter
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in HeLa-S3 cervical cancer cell line, using only public sequence and plausibility features.
EFO:0002791
true
CAGE
latent_mining/biology/tasks/apsci_triage_5b0afc0e692c
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_5b0afc0e692c/solver/public_evidence_guide.json
true
hg38
chr5:1100000-1300000
biology
regulatory_variant_triage_cached
apsci_triage_5b0afc0e692c
latent_mining/biology/tasks/apsci_triage_5b0afc0e692c/solver/task.json
search
true
ATAC
atac_subcutaneous_adipose
prioritize distal enhancer edits in adipose regulatory context
subcutaneous adipose tissue
10
latent_mining/biology/tasks/apsci_triage_5b47b3875c71/solver/candidates.json
pass
chr16
FTO/IRX3
latent_mining/biology/tasks/apsci_triage_5b47b3875c71/tb_science/instruction.md
adversarial
true
fto_irx3_adipose
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in subcutaneous adipose tissue, using only public sequence and plausibility features.
UBERON:0002190
true
ATAC
latent_mining/biology/tasks/apsci_triage_5b47b3875c71
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_5b47b3875c71/solver/public_evidence_guide.json
true
hg38
chr16:53700000-53900000
biology
regulatory_variant_triage_cached
apsci_triage_5b47b3875c71
latent_mining/biology/tasks/apsci_triage_5b47b3875c71/solver/task.json
search
true
ChIP
chip_erythroid_tf
prioritize TF-bound promoter/enhancer edits in erythroid or megakaryocytic context
erythroid/megakaryocytic
10
latent_mining/biology/tasks/apsci_triage_5bfa03cd7892/solver/candidates.json
pass
chrX
GATA1
latent_mining/biology/tasks/apsci_triage_5bfa03cd7892/tb_science/instruction.md
adversarial
true
gata1_chrx
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroid/megakaryocytic, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_5bfa03cd7892
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_5bfa03cd7892/solver/public_evidence_guide.json
true
hg38
chrX:48500000-48700000
biology
regulatory_variant_triage_cached
apsci_triage_5bfa03cd7892
latent_mining/biology/tasks/apsci_triage_5bfa03cd7892/solver/task.json
search
true
RNA_SEQ
rna_seq_airway_epithelial
prioritize airway epithelial promoter or enhancer edits affecting RNA-seq regulatory output
airway epithelial cell
10
latent_mining/biology/tasks/apsci_triage_5cecf31038f3/solver/candidates.json
pass
chr7
CFTR
latent_mining/biology/tasks/apsci_triage_5cecf31038f3/tb_science/instruction.md
adversarial
true
cftr_epithelial
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in airway epithelial cell, using only public sequence and plausibility features.
CL:0002368
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_5cecf31038f3
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_5cecf31038f3/solver/public_evidence_guide.json
true
hg38
chr7:117500000-117700000
biology
regulatory_variant_triage_cached
apsci_triage_5cecf31038f3
latent_mining/biology/tasks/apsci_triage_5cecf31038f3/solver/task.json
search
true
ChIP
chip_erythroid_tf
prioritize TF-bound promoter/enhancer edits in erythroid or megakaryocytic context
erythroid/megakaryocytic
10
latent_mining/biology/tasks/apsci_triage_5f4212c744aa/solver/candidates.json
pass
chrX
GATA1
latent_mining/biology/tasks/apsci_triage_5f4212c744aa/tb_science/instruction.md
adversarial
true
gata1_chrx
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroid/megakaryocytic, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_5f4212c744aa
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_5f4212c744aa/solver/public_evidence_guide.json
true
hg38
chrX:48500000-48700000
biology
regulatory_variant_triage_cached
apsci_triage_5f4212c744aa
latent_mining/biology/tasks/apsci_triage_5f4212c744aa/solver/task.json
search
true
ATAC
atac_subcutaneous_adipose
prioritize distal enhancer edits in adipose regulatory context
subcutaneous adipose tissue
10
latent_mining/biology/tasks/apsci_triage_60fe6953f120/solver/candidates.json
pass
chr16
FTO/IRX3
latent_mining/biology/tasks/apsci_triage_60fe6953f120/tb_science/instruction.md
adversarial
true
fto_irx3_adipose
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in subcutaneous adipose tissue, using only public sequence and plausibility features.
UBERON:0002190
true
ATAC
latent_mining/biology/tasks/apsci_triage_60fe6953f120
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_60fe6953f120/solver/public_evidence_guide.json
true
hg38
chr16:53700000-53900000
biology
regulatory_variant_triage_cached
apsci_triage_60fe6953f120
latent_mining/biology/tasks/apsci_triage_60fe6953f120/solver/task.json
search
true
RNA_SEQ
rna_seq_small_intestine
prioritize intestinal enhancer edits affecting digestive regulatory output
small intestine
10
latent_mining/biology/tasks/apsci_triage_61ba96954b68/solver/candidates.json
pass
chr2
LCT/MCM6
latent_mining/biology/tasks/apsci_triage_61ba96954b68/tb_science/instruction.md
adversarial
true
lct_mcm6
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in small intestine, using only public sequence and plausibility features.
UBERON:0002108
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_61ba96954b68
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_61ba96954b68/solver/public_evidence_guide.json
true
hg38
chr2:136600000-136800000
biology
regulatory_variant_triage_cached
apsci_triage_61ba96954b68
latent_mining/biology/tasks/apsci_triage_61ba96954b68/solver/task.json
search
true
CAGE
cage_liver
prioritize promoter or enhancer edits affecting liver regulatory output
liver
10
latent_mining/biology/tasks/apsci_triage_63d245aed6fa/solver/candidates.json
pass
chr1
PCSK9
latent_mining/biology/tasks/apsci_triage_63d245aed6fa/tb_science/instruction.md
adversarial
true
pcsk9_liver
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in liver, using only public sequence and plausibility features.
UBERON:0002107
true
CAGE
latent_mining/biology/tasks/apsci_triage_63d245aed6fa
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_63d245aed6fa/solver/public_evidence_guide.json
true
hg38
chr1:55200000-55400000
biology
regulatory_variant_triage_cached
apsci_triage_63d245aed6fa
latent_mining/biology/tasks/apsci_triage_63d245aed6fa/solver/task.json
search
true
RNA_SEQ
rna_seq_airway_epithelial
prioritize airway epithelial promoter or enhancer edits affecting RNA-seq regulatory output
airway epithelial cell
10
latent_mining/biology/tasks/apsci_triage_64c15593e086/solver/candidates.json
pass
chr7
CFTR
latent_mining/biology/tasks/apsci_triage_64c15593e086/tb_science/instruction.md
adversarial
true
cftr_epithelial
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in airway epithelial cell, using only public sequence and plausibility features.
CL:0002368
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_64c15593e086
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_64c15593e086/solver/public_evidence_guide.json
true
hg38
chr7:117500000-117700000
biology
regulatory_variant_triage_cached
apsci_triage_64c15593e086
latent_mining/biology/tasks/apsci_triage_64c15593e086/solver/task.json
search
true
ATAC
atac_tcell
prioritize promoter or enhancer edits in T-cell immune-regulatory context
CD4/T cell
10
latent_mining/biology/tasks/apsci_triage_669815584849/solver/candidates.json
pass
chr10
IL2RA
latent_mining/biology/tasks/apsci_triage_669815584849/tb_science/instruction.md
adversarial
true
il2ra_tcell
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in CD4/T cell, using only public sequence and plausibility features.
CL:0000624
true
ATAC
latent_mining/biology/tasks/apsci_triage_669815584849
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_669815584849/solver/public_evidence_guide.json
true
hg38
chr10:6000000-6150000
biology
regulatory_variant_triage_cached
apsci_triage_669815584849
latent_mining/biology/tasks/apsci_triage_669815584849/solver/task.json
search
true
ChIP
chip_erythroblast_lcr_tf
prioritize TF-bound locus-control-region enhancer edits in erythroblast regulatory context
erythroblast
10
latent_mining/biology/tasks/apsci_triage_672fd0911af7/solver/candidates.json
pass
chr11
HBB/HBE
latent_mining/biology/tasks/apsci_triage_672fd0911af7/tb_science/instruction.md
adversarial
true
hbb_lcr
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_672fd0911af7
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_672fd0911af7/solver/public_evidence_guide.json
true
hg38
chr11:5200000-5300000
biology
regulatory_variant_triage_cached
apsci_triage_672fd0911af7
latent_mining/biology/tasks/apsci_triage_672fd0911af7/solver/task.json
search
true
ChIP
chip_histone_a549
prioritize distal enhancer or super-enhancer edits in oncology regulatory context
A549 lung epithelial cancer cell line
10
latent_mining/biology/tasks/apsci_triage_677ee1a9ff10/solver/candidates.json
pass
chr8
MYC
latent_mining/biology/tasks/apsci_triage_677ee1a9ff10/tb_science/instruction.md
adversarial
true
myc_8q24
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in A549 lung epithelial cancer cell line, using only public sequence and plausibility features.
EFO:0001086
true
CHIP_HISTONE
latent_mining/biology/tasks/apsci_triage_677ee1a9ff10
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_677ee1a9ff10/solver/public_evidence_guide.json
true
hg38
chr8:127800000-128050000
biology
regulatory_variant_triage_cached
apsci_triage_677ee1a9ff10
latent_mining/biology/tasks/apsci_triage_677ee1a9ff10/solver/task.json
search
true
ChIP
chip_histone_a549
prioritize distal enhancer or super-enhancer edits in oncology regulatory context
A549 lung epithelial cancer cell line
10
latent_mining/biology/tasks/apsci_triage_67f360d8a419/solver/candidates.json
pass
chr8
MYC
latent_mining/biology/tasks/apsci_triage_67f360d8a419/tb_science/instruction.md
adversarial
true
myc_8q24
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in A549 lung epithelial cancer cell line, using only public sequence and plausibility features.
EFO:0001086
true
CHIP_HISTONE
latent_mining/biology/tasks/apsci_triage_67f360d8a419
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_67f360d8a419/solver/public_evidence_guide.json
true
hg38
chr8:127800000-128050000
biology
regulatory_variant_triage_cached
apsci_triage_67f360d8a419
latent_mining/biology/tasks/apsci_triage_67f360d8a419/solver/task.json
search
true
ChIP
chip_erythroblast_lcr_tf
prioritize TF-bound locus-control-region enhancer edits in erythroblast regulatory context
erythroblast
10
latent_mining/biology/tasks/apsci_triage_6994ece0c349/solver/candidates.json
pass
chr11
HBB/HBE
latent_mining/biology/tasks/apsci_triage_6994ece0c349/tb_science/instruction.md
adversarial
true
hbb_lcr
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_6994ece0c349
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_6994ece0c349/solver/public_evidence_guide.json
true
hg38
chr11:5200000-5300000
biology
regulatory_variant_triage_cached
apsci_triage_6994ece0c349
latent_mining/biology/tasks/apsci_triage_6994ece0c349/solver/task.json
search
true
ChIP
chip_erythroblast_tf
prioritize TF-bound enhancer edits affecting erythroid hemoglobin-switching regulatory output
erythroblast
10
latent_mining/biology/tasks/apsci_triage_6be3c59b7305/solver/candidates.json
pass
chr2
BCL11A
latent_mining/biology/tasks/apsci_triage_6be3c59b7305/tb_science/instruction.md
adversarial
true
bcl11a_erythroid
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_6be3c59b7305
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_6be3c59b7305/solver/public_evidence_guide.json
true
hg38
chr2:60500000-60800000
biology
regulatory_variant_triage_cached
apsci_triage_6be3c59b7305
latent_mining/biology/tasks/apsci_triage_6be3c59b7305/solver/task.json
search
true
ATAC
atac_tcell
prioritize promoter or enhancer edits in T-cell immune-regulatory context
CD4/T cell
10
latent_mining/biology/tasks/apsci_triage_6dfe412f9a00/solver/candidates.json
pass
chr10
IL2RA
latent_mining/biology/tasks/apsci_triage_6dfe412f9a00/tb_science/instruction.md
adversarial
true
il2ra_tcell
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in CD4/T cell, using only public sequence and plausibility features.
CL:0000624
true
ATAC
latent_mining/biology/tasks/apsci_triage_6dfe412f9a00
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_6dfe412f9a00/solver/public_evidence_guide.json
true
hg38
chr10:6000000-6150000
biology
regulatory_variant_triage_cached
apsci_triage_6dfe412f9a00
latent_mining/biology/tasks/apsci_triage_6dfe412f9a00/solver/task.json
search
true
ATAC
atac_tcell
prioritize promoter or enhancer edits in T-cell immune-regulatory context
CD4/T cell
10
latent_mining/biology/tasks/apsci_triage_6f0f22ef839a/solver/candidates.json
pass
chr10
IL2RA
latent_mining/biology/tasks/apsci_triage_6f0f22ef839a/tb_science/instruction.md
adversarial
true
il2ra_tcell
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in CD4/T cell, using only public sequence and plausibility features.
CL:0000624
true
ATAC
latent_mining/biology/tasks/apsci_triage_6f0f22ef839a
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_6f0f22ef839a/solver/public_evidence_guide.json
true
hg38
chr10:6000000-6150000
biology
regulatory_variant_triage_cached
apsci_triage_6f0f22ef839a
latent_mining/biology/tasks/apsci_triage_6f0f22ef839a/solver/task.json
search
true
CAGE
cage_hela_s3
prioritize promoter-like edits affecting CAGE TSS regulatory output
HeLa-S3 cervical cancer cell line
10
latent_mining/biology/tasks/apsci_triage_712407843d8e/solver/candidates.json
pass
chr5
TERT
latent_mining/biology/tasks/apsci_triage_712407843d8e/tb_science/instruction.md
adversarial
true
tert_promoter
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in HeLa-S3 cervical cancer cell line, using only public sequence and plausibility features.
EFO:0002791
true
CAGE
latent_mining/biology/tasks/apsci_triage_712407843d8e
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_712407843d8e/solver/public_evidence_guide.json
true
hg38
chr5:1100000-1300000
biology
regulatory_variant_triage_cached
apsci_triage_712407843d8e
latent_mining/biology/tasks/apsci_triage_712407843d8e/solver/task.json
search
true
ChIP
chip_erythroblast_tf
prioritize TF-bound enhancer edits affecting erythroid hemoglobin-switching regulatory output
erythroblast
10
latent_mining/biology/tasks/apsci_triage_71b26455aaa5/solver/candidates.json
pass
chr2
BCL11A
latent_mining/biology/tasks/apsci_triage_71b26455aaa5/tb_science/instruction.md
adversarial
true
bcl11a_erythroid
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_71b26455aaa5
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_71b26455aaa5/solver/public_evidence_guide.json
true
hg38
chr2:60500000-60800000
biology
regulatory_variant_triage_cached
apsci_triage_71b26455aaa5
latent_mining/biology/tasks/apsci_triage_71b26455aaa5/solver/task.json
search
true
ChIP
chip_erythroblast_tf
prioritize TF-bound enhancer edits affecting erythroid hemoglobin-switching regulatory output
erythroblast
10
latent_mining/biology/tasks/apsci_triage_7447356d00d4/solver/candidates.json
pass
chr2
BCL11A
latent_mining/biology/tasks/apsci_triage_7447356d00d4/tb_science/instruction.md
adversarial
true
bcl11a_erythroid
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_7447356d00d4
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_7447356d00d4/solver/public_evidence_guide.json
true
hg38
chr2:60500000-60800000
biology
regulatory_variant_triage_cached
apsci_triage_7447356d00d4
latent_mining/biology/tasks/apsci_triage_7447356d00d4/solver/task.json
search
true
RNA_SEQ
rna_seq_beta_cell
prioritize beta-cell promoter or enhancer edits affecting endocrine RNA-seq regulatory output
type B pancreatic cell
10
latent_mining/biology/tasks/apsci_triage_751d40e40846/solver/candidates.json
pass
chr11
INS
latent_mining/biology/tasks/apsci_triage_751d40e40846/tb_science/instruction.md
adversarial
true
ins_islet
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in type B pancreatic cell, using only public sequence and plausibility features.
CL:0000169
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_751d40e40846
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_751d40e40846/solver/public_evidence_guide.json
true
hg38
chr11:2100000-2300000
biology
regulatory_variant_triage_cached
apsci_triage_751d40e40846
latent_mining/biology/tasks/apsci_triage_751d40e40846/solver/task.json
search
true
RNA_SEQ
rna_seq_beta_cell
prioritize beta-cell promoter or enhancer edits affecting endocrine RNA-seq regulatory output
type B pancreatic cell
10
latent_mining/biology/tasks/apsci_triage_753269be06d4/solver/candidates.json
pass
chr11
INS
latent_mining/biology/tasks/apsci_triage_753269be06d4/tb_science/instruction.md
adversarial
true
ins_islet
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in type B pancreatic cell, using only public sequence and plausibility features.
CL:0000169
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_753269be06d4
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_753269be06d4/solver/public_evidence_guide.json
true
hg38
chr11:2100000-2300000
biology
regulatory_variant_triage_cached
apsci_triage_753269be06d4
latent_mining/biology/tasks/apsci_triage_753269be06d4/solver/task.json
search
true
CAGE
cage_hela_s3
prioritize promoter-like edits affecting CAGE TSS regulatory output
HeLa-S3 cervical cancer cell line
10
latent_mining/biology/tasks/apsci_triage_7a491161d042/solver/candidates.json
pass
chr5
TERT
latent_mining/biology/tasks/apsci_triage_7a491161d042/tb_science/instruction.md
adversarial
true
tert_promoter
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in HeLa-S3 cervical cancer cell line, using only public sequence and plausibility features.
EFO:0002791
true
CAGE
latent_mining/biology/tasks/apsci_triage_7a491161d042
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_7a491161d042/solver/public_evidence_guide.json
true
hg38
chr5:1100000-1300000
biology
regulatory_variant_triage_cached
apsci_triage_7a491161d042
latent_mining/biology/tasks/apsci_triage_7a491161d042/solver/task.json
search
true
ATAC
atac_tcell
prioritize promoter or enhancer edits in T-cell immune-regulatory context
CD4/T cell
10
latent_mining/biology/tasks/apsci_triage_7b050ae3e9c1/solver/candidates.json
pass
chr10
IL2RA
latent_mining/biology/tasks/apsci_triage_7b050ae3e9c1/tb_science/instruction.md
adversarial
true
il2ra_tcell
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in CD4/T cell, using only public sequence and plausibility features.
CL:0000624
true
ATAC
latent_mining/biology/tasks/apsci_triage_7b050ae3e9c1
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_7b050ae3e9c1/solver/public_evidence_guide.json
true
hg38
chr10:6000000-6150000
biology
regulatory_variant_triage_cached
apsci_triage_7b050ae3e9c1
latent_mining/biology/tasks/apsci_triage_7b050ae3e9c1/solver/task.json
search
true
ChIP
chip_erythroid_tf
prioritize TF-bound promoter/enhancer edits in erythroid or megakaryocytic context
erythroid/megakaryocytic
10
latent_mining/biology/tasks/apsci_triage_7c6cc1542eb4/solver/candidates.json
pass
chrX
GATA1
latent_mining/biology/tasks/apsci_triage_7c6cc1542eb4/tb_science/instruction.md
adversarial
true
gata1_chrx
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroid/megakaryocytic, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_7c6cc1542eb4
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_7c6cc1542eb4/solver/public_evidence_guide.json
true
hg38
chrX:48500000-48700000
biology
regulatory_variant_triage_cached
apsci_triage_7c6cc1542eb4
latent_mining/biology/tasks/apsci_triage_7c6cc1542eb4/solver/task.json
search
true
ATAC
atac_tcell
prioritize promoter or enhancer edits in T-cell immune-regulatory context
CD4/T cell
10
latent_mining/biology/tasks/apsci_triage_7e50f73fab90/solver/candidates.json
pass
chr10
IL2RA
latent_mining/biology/tasks/apsci_triage_7e50f73fab90/tb_science/instruction.md
adversarial
true
il2ra_tcell
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in CD4/T cell, using only public sequence and plausibility features.
CL:0000624
true
ATAC
latent_mining/biology/tasks/apsci_triage_7e50f73fab90
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_7e50f73fab90/solver/public_evidence_guide.json
true
hg38
chr10:6000000-6150000
biology
regulatory_variant_triage_cached
apsci_triage_7e50f73fab90
latent_mining/biology/tasks/apsci_triage_7e50f73fab90/solver/task.json
search
true
ATAC
atac_subcutaneous_adipose
prioritize distal enhancer edits in adipose regulatory context
subcutaneous adipose tissue
10
latent_mining/biology/tasks/apsci_triage_8242ae5aa3e7/solver/candidates.json
pass
chr16
FTO/IRX3
latent_mining/biology/tasks/apsci_triage_8242ae5aa3e7/tb_science/instruction.md
adversarial
true
fto_irx3_adipose
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in subcutaneous adipose tissue, using only public sequence and plausibility features.
UBERON:0002190
true
ATAC
latent_mining/biology/tasks/apsci_triage_8242ae5aa3e7
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_8242ae5aa3e7/solver/public_evidence_guide.json
true
hg38
chr16:53700000-53900000
biology
regulatory_variant_triage_cached
apsci_triage_8242ae5aa3e7
latent_mining/biology/tasks/apsci_triage_8242ae5aa3e7/solver/task.json
search
true
ChIP
chip_erythroid_tf
prioritize TF-bound promoter/enhancer edits in erythroid or megakaryocytic context
erythroid/megakaryocytic
10
latent_mining/biology/tasks/apsci_triage_82c170de1abe/solver/candidates.json
pass
chrX
GATA1
latent_mining/biology/tasks/apsci_triage_82c170de1abe/tb_science/instruction.md
adversarial
true
gata1_chrx
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroid/megakaryocytic, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_82c170de1abe
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_82c170de1abe/solver/public_evidence_guide.json
true
hg38
chrX:48500000-48700000
biology
regulatory_variant_triage_cached
apsci_triage_82c170de1abe
latent_mining/biology/tasks/apsci_triage_82c170de1abe/solver/task.json
search
true
ChIP
chip_erythroid_tf
prioritize TF-bound promoter/enhancer edits in erythroid or megakaryocytic context
erythroid/megakaryocytic
10
latent_mining/biology/tasks/apsci_triage_83944e549863/solver/candidates.json
pass
chrX
GATA1
latent_mining/biology/tasks/apsci_triage_83944e549863/tb_science/instruction.md
adversarial
true
gata1_chrx
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroid/megakaryocytic, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_83944e549863
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_83944e549863/solver/public_evidence_guide.json
true
hg38
chrX:48500000-48700000
biology
regulatory_variant_triage_cached
apsci_triage_83944e549863
latent_mining/biology/tasks/apsci_triage_83944e549863/solver/task.json
search
true
CAGE
cage_hela_s3
prioritize promoter-like edits affecting CAGE TSS regulatory output
HeLa-S3 cervical cancer cell line
10
latent_mining/biology/tasks/apsci_triage_83c243a8b41a/solver/candidates.json
pass
chr5
TERT
latent_mining/biology/tasks/apsci_triage_83c243a8b41a/tb_science/instruction.md
adversarial
true
tert_promoter
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in HeLa-S3 cervical cancer cell line, using only public sequence and plausibility features.
EFO:0002791
true
CAGE
latent_mining/biology/tasks/apsci_triage_83c243a8b41a
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_83c243a8b41a/solver/public_evidence_guide.json
true
hg38
chr5:1100000-1300000
biology
regulatory_variant_triage_cached
apsci_triage_83c243a8b41a
latent_mining/biology/tasks/apsci_triage_83c243a8b41a/solver/task.json
search
true
RNA_SEQ
rna_seq_airway_epithelial
prioritize airway epithelial promoter or enhancer edits affecting RNA-seq regulatory output
airway epithelial cell
10
latent_mining/biology/tasks/apsci_triage_88d6a836d277/solver/candidates.json
pass
chr7
CFTR
latent_mining/biology/tasks/apsci_triage_88d6a836d277/tb_science/instruction.md
adversarial
true
cftr_epithelial
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in airway epithelial cell, using only public sequence and plausibility features.
CL:0002368
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_88d6a836d277
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_88d6a836d277/solver/public_evidence_guide.json
true
hg38
chr7:117500000-117700000
biology
regulatory_variant_triage_cached
apsci_triage_88d6a836d277
latent_mining/biology/tasks/apsci_triage_88d6a836d277/solver/task.json
search
true
ATAC
atac_subcutaneous_adipose
prioritize distal enhancer edits in adipose regulatory context
subcutaneous adipose tissue
10
latent_mining/biology/tasks/apsci_triage_8a8f3bae3875/solver/candidates.json
pass
chr16
FTO/IRX3
latent_mining/biology/tasks/apsci_triage_8a8f3bae3875/tb_science/instruction.md
adversarial
true
fto_irx3_adipose
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in subcutaneous adipose tissue, using only public sequence and plausibility features.
UBERON:0002190
true
ATAC
latent_mining/biology/tasks/apsci_triage_8a8f3bae3875
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_8a8f3bae3875/solver/public_evidence_guide.json
true
hg38
chr16:53700000-53900000
biology
regulatory_variant_triage_cached
apsci_triage_8a8f3bae3875
latent_mining/biology/tasks/apsci_triage_8a8f3bae3875/solver/task.json
search
true
CAGE
cage_hela_s3
prioritize promoter-like edits affecting CAGE TSS regulatory output
HeLa-S3 cervical cancer cell line
10
latent_mining/biology/tasks/apsci_triage_8b2931dc8baf/solver/candidates.json
pass
chr5
TERT
latent_mining/biology/tasks/apsci_triage_8b2931dc8baf/tb_science/instruction.md
adversarial
true
tert_promoter
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in HeLa-S3 cervical cancer cell line, using only public sequence and plausibility features.
EFO:0002791
true
CAGE
latent_mining/biology/tasks/apsci_triage_8b2931dc8baf
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_8b2931dc8baf/solver/public_evidence_guide.json
true
hg38
chr5:1100000-1300000
biology
regulatory_variant_triage_cached
apsci_triage_8b2931dc8baf
latent_mining/biology/tasks/apsci_triage_8b2931dc8baf/solver/task.json
search
true
ChIP
chip_erythroid_tf
prioritize TF-bound promoter/enhancer edits in erythroid or megakaryocytic context
erythroid/megakaryocytic
10
latent_mining/biology/tasks/apsci_triage_8daa4f05b060/solver/candidates.json
pass
chrX
GATA1
latent_mining/biology/tasks/apsci_triage_8daa4f05b060/tb_science/instruction.md
adversarial
true
gata1_chrx
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroid/megakaryocytic, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_8daa4f05b060
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_8daa4f05b060/solver/public_evidence_guide.json
true
hg38
chrX:48500000-48700000
biology
regulatory_variant_triage_cached
apsci_triage_8daa4f05b060
latent_mining/biology/tasks/apsci_triage_8daa4f05b060/solver/task.json
search
true
CAGE
cage_liver
prioritize promoter or enhancer edits affecting liver regulatory output
liver
10
latent_mining/biology/tasks/apsci_triage_8fc6f2128dce/solver/candidates.json
pass
chr1
PCSK9
latent_mining/biology/tasks/apsci_triage_8fc6f2128dce/tb_science/instruction.md
adversarial
true
pcsk9_liver
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in liver, using only public sequence and plausibility features.
UBERON:0002107
true
CAGE
latent_mining/biology/tasks/apsci_triage_8fc6f2128dce
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_8fc6f2128dce/solver/public_evidence_guide.json
true
hg38
chr1:55200000-55400000
biology
regulatory_variant_triage_cached
apsci_triage_8fc6f2128dce
latent_mining/biology/tasks/apsci_triage_8fc6f2128dce/solver/task.json
search
true
ChIP
chip_erythroid_tf
prioritize TF-bound promoter/enhancer edits in erythroid or megakaryocytic context
erythroid/megakaryocytic
10
latent_mining/biology/tasks/apsci_triage_925ce5e82bbb/solver/candidates.json
pass
chrX
GATA1
latent_mining/biology/tasks/apsci_triage_925ce5e82bbb/tb_science/instruction.md
adversarial
true
gata1_chrx
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroid/megakaryocytic, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_925ce5e82bbb
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_925ce5e82bbb/solver/public_evidence_guide.json
true
hg38
chrX:48500000-48700000
biology
regulatory_variant_triage_cached
apsci_triage_925ce5e82bbb
latent_mining/biology/tasks/apsci_triage_925ce5e82bbb/solver/task.json
search
true
ChIP
chip_erythroblast_lcr_tf
prioritize TF-bound locus-control-region enhancer edits in erythroblast regulatory context
erythroblast
10
latent_mining/biology/tasks/apsci_triage_92a854646c6a/solver/candidates.json
pass
chr11
HBB/HBE
latent_mining/biology/tasks/apsci_triage_92a854646c6a/tb_science/instruction.md
adversarial
true
hbb_lcr
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ChIP objective in erythroblast, using only public sequence and plausibility features.
CL:0000765
true
CHIP_TF
latent_mining/biology/tasks/apsci_triage_92a854646c6a
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_92a854646c6a/solver/public_evidence_guide.json
true
hg38
chr11:5200000-5300000
biology
regulatory_variant_triage_cached
apsci_triage_92a854646c6a
latent_mining/biology/tasks/apsci_triage_92a854646c6a/solver/task.json
search
true
CAGE
cage_liver
prioritize promoter or enhancer edits affecting liver regulatory output
liver
10
latent_mining/biology/tasks/apsci_triage_97594e028b2e/solver/candidates.json
pass
chr1
PCSK9
latent_mining/biology/tasks/apsci_triage_97594e028b2e/tb_science/instruction.md
adversarial
true
pcsk9_liver
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in liver, using only public sequence and plausibility features.
UBERON:0002107
true
CAGE
latent_mining/biology/tasks/apsci_triage_97594e028b2e
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_97594e028b2e/solver/public_evidence_guide.json
true
hg38
chr1:55200000-55400000
biology
regulatory_variant_triage_cached
apsci_triage_97594e028b2e
latent_mining/biology/tasks/apsci_triage_97594e028b2e/solver/task.json
search
true
CAGE
cage_liver
prioritize promoter or enhancer edits affecting liver regulatory output
liver
10
latent_mining/biology/tasks/apsci_triage_981ea9136d6f/solver/candidates.json
pass
chr1
PCSK9
latent_mining/biology/tasks/apsci_triage_981ea9136d6f/tb_science/instruction.md
adversarial
true
pcsk9_liver
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in liver, using only public sequence and plausibility features.
UBERON:0002107
true
CAGE
latent_mining/biology/tasks/apsci_triage_981ea9136d6f
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_981ea9136d6f/solver/public_evidence_guide.json
true
hg38
chr1:55200000-55400000
biology
regulatory_variant_triage_cached
apsci_triage_981ea9136d6f
latent_mining/biology/tasks/apsci_triage_981ea9136d6f/solver/task.json
search
true
RNA_SEQ
rna_seq_small_intestine
prioritize intestinal enhancer edits affecting digestive regulatory output
small intestine
10
latent_mining/biology/tasks/apsci_triage_99cf28e5fecf/solver/candidates.json
pass
chr2
LCT/MCM6
latent_mining/biology/tasks/apsci_triage_99cf28e5fecf/tb_science/instruction.md
adversarial
true
lct_mcm6
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in small intestine, using only public sequence and plausibility features.
UBERON:0002108
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_99cf28e5fecf
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_99cf28e5fecf/solver/public_evidence_guide.json
true
hg38
chr2:136600000-136800000
biology
regulatory_variant_triage_cached
apsci_triage_99cf28e5fecf
latent_mining/biology/tasks/apsci_triage_99cf28e5fecf/solver/task.json
search
true
ATAC
atac_tcell
prioritize promoter or enhancer edits in T-cell immune-regulatory context
CD4/T cell
10
latent_mining/biology/tasks/apsci_triage_9d949de88434/solver/candidates.json
pass
chr10
IL2RA
latent_mining/biology/tasks/apsci_triage_9d949de88434/tb_science/instruction.md
adversarial
true
il2ra_tcell
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in CD4/T cell, using only public sequence and plausibility features.
CL:0000624
true
ATAC
latent_mining/biology/tasks/apsci_triage_9d949de88434
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_9d949de88434/solver/public_evidence_guide.json
true
hg38
chr10:6000000-6150000
biology
regulatory_variant_triage_cached
apsci_triage_9d949de88434
latent_mining/biology/tasks/apsci_triage_9d949de88434/solver/task.json
search
true
CAGE
cage_hela_s3
prioritize promoter-like edits affecting CAGE TSS regulatory output
HeLa-S3 cervical cancer cell line
10
latent_mining/biology/tasks/apsci_triage_9f08b4cb23f9/solver/candidates.json
pass
chr5
TERT
latent_mining/biology/tasks/apsci_triage_9f08b4cb23f9/tb_science/instruction.md
adversarial
true
tert_promoter
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in HeLa-S3 cervical cancer cell line, using only public sequence and plausibility features.
EFO:0002791
true
CAGE
latent_mining/biology/tasks/apsci_triage_9f08b4cb23f9
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_9f08b4cb23f9/solver/public_evidence_guide.json
true
hg38
chr5:1100000-1300000
biology
regulatory_variant_triage_cached
apsci_triage_9f08b4cb23f9
latent_mining/biology/tasks/apsci_triage_9f08b4cb23f9/solver/task.json
search
true
RNA_SEQ
rna_seq_beta_cell
prioritize beta-cell promoter or enhancer edits affecting endocrine RNA-seq regulatory output
type B pancreatic cell
10
latent_mining/biology/tasks/apsci_triage_a15bfa620002/solver/candidates.json
pass
chr11
INS
latent_mining/biology/tasks/apsci_triage_a15bfa620002/tb_science/instruction.md
adversarial
true
ins_islet
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome RNA_SEQ objective in type B pancreatic cell, using only public sequence and plausibility features.
CL:0000169
true
RNA_SEQ
latent_mining/biology/tasks/apsci_triage_a15bfa620002
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_a15bfa620002/solver/public_evidence_guide.json
true
hg38
chr11:2100000-2300000
biology
regulatory_variant_triage_cached
apsci_triage_a15bfa620002
latent_mining/biology/tasks/apsci_triage_a15bfa620002/solver/task.json
search
true
ATAC
atac_subcutaneous_adipose
prioritize distal enhancer edits in adipose regulatory context
subcutaneous adipose tissue
10
latent_mining/biology/tasks/apsci_triage_a1bce0a7f0d9/solver/candidates.json
pass
chr16
FTO/IRX3
latent_mining/biology/tasks/apsci_triage_a1bce0a7f0d9/tb_science/instruction.md
adversarial
true
fto_irx3_adipose
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome ATAC objective in subcutaneous adipose tissue, using only public sequence and plausibility features.
UBERON:0002190
true
ATAC
latent_mining/biology/tasks/apsci_triage_a1bce0a7f0d9
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_a1bce0a7f0d9/solver/public_evidence_guide.json
true
hg38
chr16:53700000-53900000
biology
regulatory_variant_triage_cached
apsci_triage_a1bce0a7f0d9
latent_mining/biology/tasks/apsci_triage_a1bce0a7f0d9/solver/task.json
search
true
CAGE
cage_liver
prioritize promoter or enhancer edits affecting liver regulatory output
liver
10
latent_mining/biology/tasks/apsci_triage_a20754c63049/solver/candidates.json
pass
chr1
PCSK9
latent_mining/biology/tasks/apsci_triage_a20754c63049/tb_science/instruction.md
adversarial
true
pcsk9_liver
Select the candidate edit most likely to satisfy the hidden cached AlphaGenome CAGE objective in liver, using only public sequence and plausibility features.
UBERON:0002107
true
CAGE
latent_mining/biology/tasks/apsci_triage_a20754c63049
true
edit action type; local reference and alternate sequence context; Carbon reference and alternate mean log probability; Carbon delta mean log probability; GC fraction shift; homopolymer shift; PWM/motif disruption or creation over public local contexts; Carbon edit-site surprisal window when per-token cache is present; ...
latent_mining/biology/tasks/apsci_triage_a20754c63049/solver/public_evidence_guide.json
true
hg38
chr1:55200000-55400000
biology
regulatory_variant_triage_cached
apsci_triage_a20754c63049
latent_mining/biology/tasks/apsci_triage_a20754c63049/solver/task.json
search
true