Javtor/biomedical-topic-categorization-validation

PMID int64 35.7M 36.4M	Title/Abstract stringlengths 22 8.78k	MeshTerms stringlengths 7 101	SemanticTypes stringlengths 4 64
36,348,551	pah exposur associ oxid stress neurotransmitt level coal miner object learn investig polycycl aromat hydrocarbon pah explor associ pah exposur oxid stress neurotransmitt level coal miner method cross section survey conduct coal miner underground first line group underground auxiliari group surfac group april june level urinari monohydroxi pah metabolit oh pah oxid stress neurotransmitt blood determin linear regress model use evalu correl oh pah oxid stress neurotransmitt level mediat role oxid stress urinari oh pah neurotransmitt chang assess mediat analysi result level hydroxynaphthalen nap hydroxi uoren flu hydroxypyren ohp urin oh pah coal miner differ workplac signific differ h p level neurotransmitt hydroxytryptamin ht norepinephrin ne epinephrin e dopamin da acetylcholin ach acetylcholinesteras ach oxid stress malondialdehyd mda f p blood three group coal miner signific differ control potenti confound factor ne content negat correl flu level ach activ also negat correl ohp level ci p ci p posit correl found ach content hydroxyphenanthren phe level ach activ also posit correl nap level phe level ci p ci p ci p addit superoxid dismutas activ correl ohp level ach activ ci p ci p mediat analysi indic ohp level may direct affect ach activ p conclus level pah underground coal miner relat higher may lead chang neurotransmitt level mediat effect oxid stress observ	D011084	T109
36,348,550	effect pprb jnk signal pathway hydroquinon induc malign transform tk cell object investig cell cycl apoptosi hydroquinon hq induc malign transform tk cell relat regulatori mechan method tk cell expos moll hq htime week week experiment group tk cell treat phosphat buffer pbs week use control group march regulatori mechan research cell divid four group control group experiment group control inhibitor group experiment inhibitor group inhibitor group ad moll p cell cycl apoptosi detect flow cytometri protein express cell cycl relat protein jnk signal pathway protein detect western blot result flow cytometri show compar control group ratio cell gg phase experiment group signific decreas p ratio cell phase signific increas p western blot demonstr protein express p rb ser ef cyclin p p ser jnk p jnk thrtyr c jun p c jun ser p regul protein express rb p p p signific regul expos sp compar experiment group signific chang cell cycl distribut p apoptosi rate p experiment inhibitor group express c jun p protein regul express rb p protein regul experiment inhibitor group conclus hq induc tk cell malign transform cell cycl arrest phase pprb signal pathway inhibit jnk signal pathway activ howev activ jnk signal pathway may involv regul cell cycl	D006873;D020935	T121;T044;T109
36,348,511	algorithm instrument rapid spatial frequenc domain fluoresc diffus optic imag significancerapid estim depth margin fluoresc target buri tissu surfac could improv upon current imag guid surgeri techniqu tumor resectionaimw describ algorithm instrument permit rapid estim depth transvers margin fluoresc target turbid media work aim introduc experiment demonstr character methodologyapproachspati frequenc domain fluoresc diffus optic tomographi sfd fdot techniqu adapt rapid comput inexpens estim fluorophor target depth later margin algorithm util variat diffus fluoresc intens respect spatial modul frequenc comput target depth later margin determin via analyt invers data use depth inform obtain first step character method perform use fluoresc contrast target embed tissu simul phantomsresultssingl multipl target signific later size imag vari depth deep cm phantom data analysi show good depth sensit reconstruct transvers margin most within error true marginsconclusionsth studi suggest rapid sfd fdot approach could use resect surgeri broad first step rigor sfd fdot reconstruct experi permit evalu current limit	D041622;D025321	T060;T061
36,348,509	accur earli predict wound heal outcom burn injuri use wavelet shannon entropi terahertz time domain waveform significancesever burn injuri caus signific hypermetabol alter high dynam hard predict requir acut critic care clinic assess sever burn injuri high subject consist report inaccur therefor util imag modal crucial reach object accur burn assess modalityaimw describ non invas techniqu use terahertz time domain spectroscopi thz tds wavelet packet shannon entropi automat estim burn depth predict wound heal outcom thermal burn injuriesapproachw creat burn injuri differ sever grade two porcin model use scald contact method inflict use thz portabl handheld spectral reflect phasr scanner obtain vivo thz tds imag use energi shannon entropi ratio wavelet packet coeffici thz tds waveform day creat supervis support vector machin svm classif model histolog assess burn biopsi serv ground truthresultsw achiev accuraci rate predict wound heal outcom determin histolog measur epitheli rate day post burn induct use thz tds measur obtain day furthermor report accuraci rate automat diagnosi superfici partial thick deep partial thick full thick burn respect use multiclass svm modelconclusionsth thz phasr scanner promis robust high speed accur diagnost modal improv clinic triag burn manag	D012867;D055068	T022;T059
36,348,508	distinct clinicopatholog featur ovarian endometriosi long term exposur mifepriston mifepriston use treat endometriosi caus constel endometri alter studi investig effect long term mifepriston ovarian endometriosi	D004715;D010048;D010051	T047;T191
36,348,498	periop outcom uniport versus two port three port video assist thoracoscop surgeri lung cancer systemat review meta analysi uniport video assist thoracoscop surgeri vat appli wide treatment lung cancer recent year studi report uniport vat might provid better outcom multiport vat howev periop outcom uniport vat compar two port three port vat respect yet studi comprehens scale meta analysi studi compar periop efficaci among uniport two port three port vat	D020775;D008175	T061;T191
36,348,497	modif mesenchym stem cell cartilag target therapi osteoarthr oa chronic degen joint diseas character destruct articular cartilag sclerosi subchondr bone joint dysfunct pathogenesi attribut direct damag mechan destruct joint tissu mesenchym stem cell mscs suggest potenti strategi treatment oa shown therapeut effect oa howev specif fate mscs intraarticular inject includ cell attach prolifer differenti death still unclear guarante stem cell retain cartilag tissu enact repair direct home mscs import determin efficaci msc base cartilag repair recent studi reveal uniqu home capac mscs target modif improv abil promot tissu regener comprehens review home effect stem cell joint highlight progress toward target modif mscs futur develop target system acceler tissu regener benefit target tissu repair	D045164;D059630;D002358;D010003	T061;T047;T025;T024
36,348,496	develop test new applic measur motion cervic spine cervic myelopathi progress diseas earli detect treatment contribut prognosi evalu cervic intervertebr instabl simpl x ray use clinic set inform instabl import understand caus myelopathi evalu intervertebr instabl x ray complic reduc burden clinician system automat measur rang motion develop compar flex extend posit later view simpl x ray cervic spine accuraci system verifi comparison spine surgeon resid determin whether system could withstand actual use	D002574;D013118	T023;T047
36,348,495	evid anthocyanin betalain pigment genus hylocereus weak respond zhou bmc genom combin transcriptom metabolom analysi pitaya fruit unveil mechan under peel pulp color format publish bmc genom given evolutionari conserv anthocyanin biosynthesi pathway betalain pigment speci open idea speci anthocyanin betalain might exist howev absenc lc msms spectra appar lack biolog replic comparison authent standard find zhou bmc genom strong basi propos presenc anthocyanin betalain pigment pitaya addit analysi dataset indic misidentif import gene omiss key flavonoid anthocyanin synthesi gene an dfr final analysi rna seq dataset reveal correl anthocyanin biosynthesi gene express pigment status	D050858;D029421	T123;T002;T109
36,348,494	applic mapl comput strong fuzzi chromat polynomi fuzzi graph field graph theori mapl technic comput form use solv problem articl appli mapl find strong fuzzi chromat polynomi fuzzi graph relat moreov appli mapl obtain strong fuzzi chromat number fuzzi graph use strong fuzzi chromat polynomi	D031002	T002
36,348,492	indirect social contact intervent reduc mental health relat stigma low middl incom countri systemat review mental health relat stigma discrimin complex widespread issu negat effect numer aspect life peopl live experi mental health condit research show social contact best evid base intervent reduc stigma within context rapid develop remot technolog covid relat restrict face face contact aim paper categoris compar defin indirect social contact isc intervent reduc stigma discrimin mental health low middl incom countri lmic	D000086382;D001523	T047;T067;T048
36,348,491	assess left ventricular diastol function children hivaid attend tertiari health facil enugu nigeria doppler echocardiograph studi determin preval factor associ left ventricular diastol dysfunct children hivaid	D000163	T047
36,348,489	chronic rhinosinus associ chronic bronchiti five year follow telemark studi chronic rhinosinus crs associ generalis airway inflamm studi address relationship crs chronic bronchiti cb	D029481;D012852;D001249;D012220	T047
36,348,488	factor influenc adher antiretrovir therapi experi peopl live hiv healthcar provid sierra leon qualit studi antiretrovir therapi art primari mode treatment human immunodefici virus hiv slow diseas progress reduc spread infect hiv treatment also known requir high level adher achiev good treatment outcom viral load suppress sierra leon peopl live hiv plhiv non adher first year treatment understand reason behind high rate non adher perspect plhiv health worker critic develop strategi improv adher qualit studi root field public health servic identifi barrier facilit influenc adher antiretrovir treatment sierra leon method qualit studi design use depth interview four healthcar worker plhiv two district sierra leon freetown bo interview analyz use ground theori approach identifi emerg theme data	D055118;D015658	T033;T055;T081;T047
36,348,486	rare case report primari sjgren syndrom clinic characterist similar clipper primari sjgren syndrom pss autoimmun inflammatori diseas character dryness eye mouth mucous membran patient pss also present extraglandular manifest pulmonari kidney nervous system involv central nervous system cns manifest rare describ pss	D002493;D012859	T047
36,348,484	integr nutrit obes prevent consider institut invest decis regard food compani australian invest sector perspect grow recognit current food system unhealthi unsustain increas shift toward suppli market unhealthi ultra process food beverag larg food compani hold substanti power within food system present signific barrier progress address issu relat nutrit obes prevent institut investor pension fund play key role influenc corpor govern practic increas incorpor environment social govern esg consider within invest decis consid nutrit obes prevent institut investor present potenti avenu drive increas food industri account popul health impact studi investig view stakehold australian invest sector incorpor nutrit obes prevent consider within institut invest decis make regard food compani	D019649;D009752	T033;T057
36,348,483	predict exercis induc desatur copd patient without rest hypoxemia retrospect studi univers accept criterion assess exercis induc desatur eid purpos studi compar two method regular use determin eid copd patient well explor risk factor predictor relat eid	D029424;D011656;D004646	T047;T046
36,348,482	anxieti depress symptom albuminuria risk acut myocardi infarct norwegian hunt cohort studi studi suggest increas risk outcom peopl joint exposur share common causal pathway object studi determin risk incid acut myocardi infarct ami follow exposur albuminuria andor anxieti depress symptom	D000419;D009203	T033;T047
36,348,481	pattern chang obes indic cardiometabol risk factor diagnosi type diabet two decad follow tehran lipid glucos studi identifi pattern variat obes indic cardiometabol risk factor diagnosi type diabet could provid insight critic period drastic chang occur facilit target intervent prevent diabet therefor studi sought explor pattern chang obes indic cardiometabol risk factor diabet diagnosi	D003924;D002318	T047
36,348,480	later flow assay lfa diagnosi covid associ pulmonari aspergillosi capa singl center experi invas pulmonari aspergillosi ipa seen coronavirus covid report differ incid defin covid associ pulmonari aspergillosi capa detect galactomannan antigen import diagnost step diagnos ipa enzym link immunoassay elisa frequent use method later flow assay lfa increas use high sensit specif rapid diagnosi present studi aim compar sensit lfa elisa diagnosi capa covid patient follow hospit icu pandem icu p	D000086382;D055744;D055732	T047;T067
36,348,479	consum percept legal cannabi product canada repeat cross section studi consum percept legal cannabi product may drive willing purchas illeg legal market howev littl known topic current studi examin percept legal product among canadian cannabi consum year period follow feder legal non medic cannabi	D002188	T121;T002;T167;T109
36,348,478	comparison machin learn model bluetongu risk predict seropreval studi small rumin bluetongu bt diseas concern anim breeder question mind whether predict risk diseas occur main object studi enhanc accuraci bt risk predict reli machin learn ml approach help fulfil inquiri sever risk factor bt affect occurr magnitud anim infect virus report global addit risk factor sex age speci season uneven affect anim health welfar therefor seropreval studi data appar healthi anim sheep goat five differ provinc egypt use analyz compar perform algorithm predict bt risk	D001819;D015511;D012757	T047
36,348,477	periop transcutan electr acupoint stimul ptea pain manag major spinal surgeri patient lumbar disc herniat seen patient lumbar back pain common spine disord demand surgic correct spinal surgeri one effect manag patient howev current surgic techniqu still present complic chronic pain patient underw lumbar surgeri signific impact patient qualiti life research studi shown transcutan electr acupoint stimul tea may reduc cumul dosag intraop anesthet well postop pain medic patient	D015669;D059408	T061;T029
36,348,476	phase iiiii trial hyperimmun anti covid intraven immunoglobulin c ivig therapi sever covid patient studi protocol random control trial covid pose global health challeng million cumul case million cumul death report till januari world health organ sever potenti treatment treat covid clinic trial includ antivir steroid immunomodul non specif ivig monoclon antibodi passiv immun convalesc plasma need produc anti covid ivig therapi must continu alongsid current treatment modal consid virus still mutat variant concern context present studi exploit pool diversifi convalesc plasma collect recov covid patient propos hyperimmun anti covid intraven immunoglobulin c ivig therapi would abl counter new infecti covid variant neutral virus particl success outcom phase iii clinic trial c ivig current studi aim evalu safeti efficaci singl low dose c ivig sever covid patient phase iiiii clinic trial	D000086382;D011024;D018352	T047;T067
36,348,474	chang prevent behaviour covid vaccin thailand cross section studi protect behaviour eg mask wear handwash avoid social gather mass vaccin effect way control coronavirus diseas covid pandem previous studi found peopl get vaccin may chang protect behaviour thai govern endors sever mix match vaccin regimen elimin insuffici vaccin brand studi aim determin level protect behaviour chang covid vaccin relationship various vaccin regimen thailand	D000086382	T047;T067
36,348,473	effect relat mechan alpha adrenerg receptor inhibitor phentolamin rabbit model acut pulmonari embol combin shock observ effect mechan alpha adrenerg receptor inhibitor phentolamin ptl rabbit model acut pulmonari embol ape combin shock	D011655;D012769;D015186	T047;T046;T015
36,348,471	lineag abund estim sar cov wastewat use transcriptom quantif techniqu effect monitor spread sar cov mutant essenti effort counter ongo pandem predict lineag abund wastewat howev technic challeng show sequenc sar cov rna wastewat appli algorithm initi use transcriptom quantif estim lineag abund wastewat sampl find high variabl signal among individu sampl overal trend match observ sequenc clinic sampl thus clinic sequenc remain sensit techniqu popul surveil wastewat sequenc use monitor trend mutant preval situat clinic sequenc unavail	D000086402;D000086382	T005;T067;T047
36,348,470	depress associ younger age femal sex obes smoke physic inact patient newli diagnos type diabet swedish multicentr cross section studi depress risk factor type diabet td cardiovascular diseas cvd aim explor preval depress anxieti antidepress use obes hemoglobin ac mmolmol life style factor pre exist cvd patient newli diagnos td explor associ depress compar swedish general popul data	D003924;D002318	T047
36,348,468	mix liver kidney transcriptom dataset darevskia valentini rock lizard studi perform frame bigger studi dedic genom transcriptom parthenogenesi vertebr among vertebr oblig parthenogenesi first describ lizard genus darevskia genus found parthenogenet speci origin via interspecif hybrid remain unknown genet genom factor play key role generat parthenogenet organ compar genom transcriptom analysi parthenogen parent speci may elucid problem darevskia valentini patern speci four seven parthenogen genus promot particular import speci generat parthenogenet form	D008116	T014
36,348,467	prepar character vitro cytotox nanoliposom load anti tubercular drug tgf sirna improv spinal tuberculosi therapi tuberculosi tb repres bacteri infect affect mani individu year potenti lead death overexpress transform growth factor tgf primari immunomodulatori function human tuberculosi work aim develop nanoliposom facilit deliveri anti tubercular product thp deriv human macrophag mycobacterium host cell evalu drug effici well effect tgf specif short interf rna sirna deliveri system employ nanoliposom	D053773;D014399	T123;T047;T121;T116
36,348,466	advers emot resili among syrian refuge netherland syrian refuge compris vast major refuge netherland although research carri factor promot refuge resili empir studi resili syrian refuge	D012036	T098
36,348,465	rage display sex specif differ obes induc adipos tissu insulin resist receptor advanc glycat end product rage play import role obes associ insulin sensit also previous report rage defici improv insulin resist obes induc adipos tissu current studi aim elucid sex specif mechan rage defici adipos tissu metabol regul system glucos homeostasi	D007333	T046
36,348,463	decellular bovin ovarian nich restor function cumulus endotheli cell recent decellular techniqu introduc one tissu engin procedur treatment various defici aim assess dynam activ ccs huvec within decellular bovin ovarian tissu transplant subcutan rat ovarian tissu decellular use cocktail consist differ chemic effici decellular assess use hematoxylin eosin dapi stain cell surviv evalu use ldh leakag assay thereaft decellular sampl recellular use huvec ccs encapsul insid algin gelatin hydrogel transplant subcutan rat exist cd estrogen posit cell assess use immunohistochemistri stain	D005109;D042783	T025;T024
36,348,461	evolut function development dynam pseudogen mammal pseudogen excel marker genom evolut emerg crucial regul develop diseas especi cancer howev systemat function character evolut pseudogen remain larg unexplor	D011544;D009369	T191;T028
36,348,460	inclus progress criteria extern randomis pilot trial cross section studi fund applic submit nihr research patient benefit programm extern randomis pilot trial aim assess whether futur definit randomis control trial rct feasibl pre specifi progress criteria help guid interpret pilot trial find decid whether definit trial conduct aim examin research report plan assess progress criteria extern pilot trial fund applic submit nihr research patient benefit programm	D012107	T062;T096;T170;T081;T169
36,348,459	novel homozyg mutat trappc gene caus autosom recess non syndrom intellectu disabl etiolog intellectu disabl divers includ genet environment factor genet caus intellectu disabl rang chromosom aberr singl gene disord trappc gene report caus autosom recess form intellectu disabl patient consanguin non consanguin famili around world	D008607;D008831	T019;T047;T048
36,348,457	natur killer cell clinic develop non engin engin combin therapi natur killer nk cell uniqu immun effector abl kill cancer cell direct recognit surfac ligand without prior sensit allogen nk transfer high valuabl treatment option cancer recent emerg hundr clinic trial pave way final achiev market author advantag nk cell therapi includ use allogen cell sourc shelf avail risk graft versus host diseas gvhd allogen nk cell therapi reach clinic stage ex vivo expand differenti non engin cell chimer antigen receptor car engin cd engin product combin therapi antibodi prime agent drug review summar recent clinic status allogen nk cell base therapi treatment hematolog solid tumor discuss main characterist differ cell sourc use nk product develop use cell manufactur process engin method strategi adopt genet modifi product chosen approach combin therapi compar analysi nk base non engin engin combin therapi present examin choic made product develop regard nk cell sourc target tumor indic solid hematolog cancer clinic trial outcom discuss avail assess comparison preclin data regulatori challeng product approv review highlight lack specif requir standard product addit competit landscap busi field present review offer comprehens overview effort driven biotech pharmaceut compani academ center bring nk cell therapi pivot clinic trial stage market author	D000076962;D009369;D019337	T129;T191;T116;T192
36,348,455	cladribin treatment improv cortic network function mous model autoimmun encephalomyel cladribin synthet purin analogu interfer dna synthesi repair next disrupt cellular prolifer activ divid lymphocyt compound approv treatment multipl sclerosi ms cladribin cross blood brain barrier suggest potenti effect central nervous system cns resid cell explor compart specif immunosuppress well potenti direct neuroprotect effect oral cladribin treatment experiment autoimmun encephalomyel eae mice	D004681;D018696;D004679	T121;T047;T050;T169
36,348,454	icu bridg program volunt bridg medicin peopl togeth intens care unit icu emot tax environ patient famili member increas risk long term physic psycholog consequ critic ill known collect post intens care syndrom pic environment strain lead high incid staff turnov burnout	D007362;D016638	T047;T073;T093
36,348,453	intensifi tuberculosi treatment reduc mortal hiv infect uninfect patient tuberculosi mening intens tbm studi protocol phase iii random control trial tubercul mening tbm lethal disabl form tuberculosi tb particular sub saharan africa current anti tb treatment poor effect sinc tbm mortal reach hiv negat patient hiv co infect patient reduc tbm induc morbid mortal intens tbm trial evalu two intervent hiv infect uninfect patient anti tb treatment intensif use oral high dose rifampicin mgkg daili linezolid mg daili mg daili first week anti tb treatment use adjunct aspirin mg daili	D014390;D015658	T047
36,348,452	respiratori ill virus infect special emphasi covid virus emerg pose challeng treatment option uniqu would know complet henc mani virus caus high morbid mortal long time despit larg divers virus share common characterist infect least differ respiratori born virus report belong various virus taxonom famili mani virus multipli caus damag upper lower respiratori tract descript virus comparison concern epidemiolog molecular characterist diseas manifest diagnosi treatment lack inform help diagnos differenti formul control measur faster lead caus acut ill worldwid acut respiratori infect ari respons near million death everi year most young children infant lower respiratori tract infect fourth common caus death global non infecti chronic condit review aim present characterist differ virus caus respiratori infect highlight uniqu sar cov expect review help understand similar differ among close relat virus caus respiratori infect formul specif prevent control measur	D000086382;D012141;D014780	T047;T005;T067
36,348,446	characterist cost electr scooter injuri helsinki retrospect cohort studi incid electr scooter e scooter injuri increas drastic numer countri widespread avail share e scooter econom impact societi broader perspect studi aim estim incid e scooter injuri describ injuri pattern estim cost e scooter injuri	D006260;D006259	T073;T037
36,348,445	success breastfeed follow level ii nicu stay qatar longitudin studi exclus breastfeed essenti need mother newborn babi cultur practic employ demand signific influenc feed practic associ neonat intens care unit nicu admiss breastfeed outcom variabl data qatar middl east particular limit henc studi aim estim rate breastfeed time nicu discharg rate success breastfeed nicu discharg qatar well babi follow up	D001942;D007363	T073;T055;T040;T093;T058
36,348,444	case primari optic pathway demyelin caus oncocyt oligodendrogliopathi unknown origin report case year old woman present acut onset dizzi gait dysbal blur vision magnet reson imag includ tesla tesla imag reveal hyperintens hypointens non contrast enhanc lesion strict confin white matter affect right optic radiat extens ophthalmolog examin yield mild quadrantanopia sign optic neuropathi lesion biopsi neuropatholog evalu reveal demyelin lesion mark tissu vacuol granular myelin disintegr accompani mild cell infiltr notabl absenc myelin uptak macrophag oligodendrocyt strike enlarg display oncocyt characterist show cytoplasm accumul mitochondria mild abnorm morpholog electron microscopi diagnosi multipl sclerosi exclud hard diseas variant leber hereditari optic neuropathi suspect howev neither pcr relev mutat whole exom sequenc yield known pathogenet mutat patient genom present pattern demyelin tissu injuri unknown etiolog oncocyt chang oligodendrocyt lack adequ phagocyt respons macrophag best knowledg describ	D029242;D009103;D066127	T047;T024;T023
36,348,440	review applic exposom paradigm unveil environment determin age relat diseas age relat diseas account almost half diseas among adult worldwid incid substanti affect exposom sum exogen endogen environment exposur human bodi respons exposur throughout entir lifespan herein perform comprehens review epidemiolog literatur determin key element exposom affect develop age relat diseas role age hallmark process find exposur assess previous age studi use reductionist approach wherebi effect singl environment factor specif class environment factor develop age relat diseas examin lack holist unbias understand effect multipl environment factor develop age relat diseas address propos sever research strategi base exposom framework could advanc understand particular mechanist perspect environment factor affect develop age relat diseas discuss statist method method use exposom wide associ studi particular focus multiom technolog also address futur challeng opportun realm multidisciplinari approach genom exposom epidemiolog furthermor provid perspect precis public health servic vulner popul public communic integr risk exposur inform bench bedsid translat research age relat diseas	D000081413	T058
36,348,439	gap sexual transmit infect screen among youth live hiv alabama gap sexual transmit infect sti test lead poor health outcom due untreat ill among youth live hiv ylhiv thus object studi examin sti test behavior outcom among sampl ylhiv southern unit state clinic record ylhiv receiv hiv care alabama evalu receipt sti test gonorrhea chlamydia syphili preval posit test result factor associ test outcom clinic visit	D013587;D015658;D012749;D006069;D002690	T047
36,348,437	express ki p relat hpv squamous cell carcinoma extern auditori canal squamous cell carcinoma extern auditori canal eacscc uncommon tumor respons head neck malign although remark research evid exhibit high risk human papillomavirus hpv account consider head neck malign role pathogenesi eacscc yet determin	D030361;D002294;D006258	T047;T191
36,348,436	anti leucin rich glioma inactiv enceph two case report review literatur anti leucin rich glioma inactiv enceph newli emerg entiti character frequent faciobrachi dyston seizur wide spectrum subacut clinic symptom seizur type mood behavior chang memori loss awar differenti diagnosi psychogen nonepilept seizur mesial tempor limbic structur basal ganglia common involv region	D020363;D004660;D005910	T047;T191
36,348,435	ventricular arrhythmia burden patient implant cardiovert defibril remot patient monitor differ time interv covid pandem current studi investig whether chang patient care time covid pandem especi reduct person visit would result deterior arrhythm clinic condit patient implant cardiovert defibril icd remot patient monitor	D017147;D000086382	T047;T074;T067
36,348,433	molecular characterist norovirus sporad outbreak case acut gastroenter sewag sichuan china norovirus high divers constant surveil essenti prevent control norovirus gastroenter	D029322;D017250;D005759	T005;T047
36,348,432	death human cytomegalovirus infect girl congenit thymic dysplasia report case girl congenit thymic dysplasia refractori dissemin human cytomegalovirus cmv infect diagnos autopsi addit diagnos cell lymphopenia immunodefici receiv antivir therapi ganciclovir gcv valganciclovir v gcv enhanc foscarnet cmv viral load vl monitor elev retin interstiti pneumonia hepat phenotyp cell lymphopenia uncertain limit altern therapi whole exom sequenc wes lymphocyt subset panel autopsi girl die progress respiratori failur septic shock ten month age sever dissemin cmv infect typic develop infant primari matern infect occur earlier gestat peopl weaken host immun system individu cmv infect initi immunodefici associ poor prognosi similar patient secondari immunodefici case describ difficult treatment prognosi cmv infect patient congenit immunodefici highlight import earli aggress anti cmv antivir therapi immunodefici vl monitor drug resist role cell cmv infect	D003586;D008231	T047
36,348,431	high preval resist third generat cephalosporin detect among clinic isol sentinel healthcar facil lago nigeria antimicrobi resist amr bacteri pathogen worldwid concern demand immedi attent inform amr origin high incom countri littl known burden africa particular nigeria use four sentinel site general hospit lago state studi sought estim burden amr	D002439;D013203	T047;T195;T109
36,348,430	field test new icd code system method earli experi icd beta version beta version intern classif diseas th revis mms icd need test field test involv real world applic new code examin usabl describ creat dataset character usabl icd code set coder compar icd icd ca canadian modif refer standard dataset diagnos real world usabl encompass code select time code complet inpati chart use icd compar icd ca	D038801;D006761	T170;T073;T093
36,348,429	profession wellb turnov intent among child therapist comparison therapist train untrain trauma focus cognit behavior therapi poor profession wellb job turnov challeng child mental health clinic despit increas interest implement evid base practic ebp mental health servic littl known use ebp may influenc therapist profession wellb turnov intent investig compar averag level compass satisfact burnout secondari traumat stress turnov intent therapist train ebp trauma focus cognit behavior therapi tf cbt untrain therapist also explor preval associ person organiz outcom	D000068376;D002055;D015928	T061;T048
36,348,427	evalu first aid skill train systemat review abl help save live layperson recommend undergo first aid train aim review explor varieti element measur system assess effect first aid train differ aspect first aid skill includ practic skill knowledg emot perspect	D005392;D016887	T061
36,348,426	sagitt intervertebr rotat motion deep learn base measur flexion neutral extens cervic later radiograph analysi sagitt intervertebr rotat motion sirm provid import inform evalu cervic diseas deep learn wide use spinal paramet measur howev investig spinal motion analysi purpos studi develop deep learn base model fulli autom measur sirm base flexion neutral extens cervic later radiograph evalu applic flexion extens fe flexion neutral fn neutral extens ne motion analysi	D002574;D000077321	T023;T066
36,348,424	effect shunt surgeri corticospin excit idiopath normal pressur hydrocephalus transcrani magnet stimul studi idiopath normal pressur hydrocephalus inph multifactori diseas present classic symptom triad cognit declin gait disturb urinari incontin symptom allevi shunt surgeri etiolog symptom remain unclear navig transcrani magnet stimul ntms appli character corticospin excit cortic motor function shunt surgeri order elucid pathophysiolog inph also aim determin whether ntms could appli predict tool pre surgic work inph	D006850;D009044	T047;T029;T023
36,348,423	longitudin trend produc purchas behavior descript studi transact level data loyalti card household household food purchas hfp pathway communiti food environ food avail household consumpt hfp data emerg altern monitor popul dietari trend time paper investig use loyalti card dataset unexplor sourc continu collect hfp data describ tempor trend household produc purchas	D003258;D005191	T098;T080;T099;T062;T079;T054;T102
36,348,422	effect mhealth base exercis insulin sensit patient hepatocellular carcinoma insulin resist mish protocol random control trial import insulin resist gain increas attent play import role carcinogenesi hepatocellular carcinoma hcc although exercis import intervent lower insulin resist easi hcc patient maintain high complianc appropri exercis mobil health mhealth wearabl devic solut carri adjust supervis exercis normal insulin resist patient hcc develop hcc specif applic equip patient center exercis paper present random control trial protocol compar intervent group control group determin whether mhealth base exercis effect normal insulin sensit hcc patient insulin resist anticanc treatment	D007333;D006528;D017216;D008113	T058;T046;T191
36,348,421	induct mechan cigarett smoke compon cscs dyslipidemia hepat steatosi rat purpos studi explor effect cigarett smoke compon csc exposur serum lipid level rat under molecular mechan	D000073865;D005234;D050171;D035683	T123;T055;T114;T047;T046
36,348,420	laparoscop versus open distal gastrectomi elder patient advanc gastric cancer retrospect compar studi laparoscop radic distal gastrectomi ldg frequent perform local advanc distal gastric cancer agc open distal gastrectomi odg howev benefit ldg elder agc patient agc lap remain unclear	D013274;D010535	T060;T191;T061
36,348,418	childhood diabet mellitus earli onset kidney diseas later life nationwid popul base match cohort studi empir evid remain inconclus associ diabet mellitus dm children earli onset kidney diseas later life littl known effect dm type ie type diabet tdm type diabet tdm childhood type specif kidney diseas aim evalu associ childhood dm overal type specif earli onset kidney diseas later life	D003922;D003924;D007674;D051437	T047
36,348,417	swedish trial embol middl mening arteri versus surgic evacu chronic subdur hematoma swemma nation month multi center random control superior trial parallel group assign open treatment alloc blind clinic outcom assess chronic subdur hematoma csdh one common neurosurg disord incid rise routin treatment neurosurg hematoma evacu associ recurr rate recent year endovascular embol middl mening arteri emma garner much attent due recurr rate low sever random control trial plan ongo trial convent neurosurg treatment without adjunct endovascular embol compar propos trial aim conduct head head comparison neurosurg endovascular treatment stand alon treatment	D020200	T046
36,348,415	genom wide profil retrovir dna integr effect clinic pre infus car cell product clinic car cell therapi use integr vector system repres promis approach treatment hematolog malign lentivir retrovir vector common use vector manufactur process howev integr pattern viral vector subsequ effect car cell product still unclear	D016086;D012190	T005
36,348,414	sex differ medial prefront cortic glutam system dysregul prefront cortex under varieti psychiatr ill includ substanc use disord depress anxieti despit establish sex differ preval present ill neural mechan drive differ larg unexplor investig potenti sex differ glutamaterg transmiss within medial prefront cortex mpfc goal experi determin baselin sex differ transmiss within region may underli sex differ diseas involv dysregul prefront cortex	D018698;D012727	T123;T032;T121;T116
36,348,413	molecular test deliv person chemotherapi recommend risk undertreat adjuv set cancer treatment de escal strategi goal omit minim treatment patient without compromis outcom histor elig adjuv treatment sole reli patient clinic tumor patholog characterist turn centuri base new biolog understand molecular base strategi test sometim implement	D001943;D003110	T191
36,348,411	neighborhood environment factor link hospit older peopl viral lower respiratori tract infect spain case crossov studi lower respiratori tract viral infect lrti signific caus morbid mortal older peopl worldwid analyz associ short term exposur environment factor climat factor outdoor air pollut hospit admiss viral lrti diagnosi older adult	D000393;D000397;D012141	T131;T047;T069;T080
36,348,410	drive assess preclin alzheim diseas progress date path forward chang drive behaviour may start preclin stage alzheim diseas ad under ad biolog process begun presenc cognit normal summar emerg evid suggest preclin ad may impact everyday drive behaviour main increas evid link drive perform behaviour ad biomark cognit intact older adult studi found subtl yet detect differ drive associ ad biomark status among cognit intact older adult	D000544	T047;T048
36,348,409	improv malaria surveil electron integr diseas surveil respons eidsr system mainland tanzania tanzania made remark progress reduc malaria burden aim transit malaria control sub nation elimin electron week month report platform use district health inform system dhis introduc week report implement mobil phone base integr diseas surveil respons eidsr platform progress scale public privat health facil studi describ roll larg scale implement eidsr compar consist week eidsr month dhis malaria indic data report includ assess use malaria outbreak detect case base surveil cbs low transmiss area	D008288;D063005	T047;T170
36,348,408	nkd correl occurr progress prognosi thyroid carcinoma thyroid carcinoma thca preval type tumor endocrin system nkd increas evidenc play crucial role mani cancer except thca herein aim explor potenti role nkd thca	D002352;D013964	T123;T191;T116
36,348,405	promot synthet degrad activ stat parp inhibit role poli adp ribosyl ation calpain autophagi report parp regul gene whose product crucial asthma part control stat integr specul calpain depend mechan wish deciph parp stat relationship context intracellular traffick promot occup transcript factor target gene integr presenc calpain connect autophagi	D000074747;D011065	T126;T116;T044
36,348,401	complianc hand hygien practic among nurs staff secondari healthcar hospit kuwait hand hygien hh among healthcar worker especi nurs main prevent measur control healthcar associ infect complianc hand hygien cwhh remain low various set includ kuwait studi aim assess knowledg attitud toward cwhh among nurs staff secondari care hospit kuwait	D063373;D003428;D009740	T055;T047;T097
36,348,400	prognost potenti liver injuri patient dilat cardiomyopathi retrospect studi liver injuri li frequent observ patient dilat cardiomyopathi dcm wherea prognost valu remain blurri attempt apprais prognost effect li patient dcm	D002311	T047
36,348,398	oral manifest associ inflammatori bowel diseas earli endoscop find patient spondyloarthr spondyloarthr spa group autoinflammatori disord primari extra articular manifest inflammatori bowel diseas ibd oral caviti part gastrointestin tract signific compromis ibd mani case first site clinic manifest ibd studi aim identifi chang oral mucosa associ onset ibd associ endoscopichistolog find	D013281;D025241;D015212;D019226;D005891;D012216	T047
36,348,397	investig job satisfact amongst voluntari counsel test center health center iran job satisfact person feel job personnel good feel work destroy plan intent unintent present research aim investig compar job satisfact employe therapist voluntari counsel test center versus health center provinc iran	D007588;D017132	T082;T041
36,348,396	nonunion humer medial condyl fractur caus excess function exercis case report review literatur medial epicondyl fractur one common humerus fractur humer medial condyl fractur hmcf rare nonunion medial humer condyl fractur due function exercis less common	D004551;D006810;D005599	T046;T037;T030
36,348,395	vector born pathogen potenti relev dissemin reloc cat larg popul unown cat constitut anim welfar ecolog societ public health issu worldwid reloc home current carri mani part world intent reliev suffer social problem contribut ethic human popul control cat popul understand individu cat lifestyl diseas status veterinari team profession work cat chariti help prevent sever cat stress spread felin pathogen especi vector born pathogen overlook cat articl discuss issu reloc home unown cat global perspect also review zoonot non zoonot infecti agent cat give list practic recommend veterinari team profession deal home cat final present consensus statement consolid th symposium companion vector born diseas cvbd world forum ultim help veterinari team profession understand problem role help prevent manag vector born pathogen reloc cat	D004199;D002371	T047;T008
36,348,394	effect attach posit molar intrus clear align finit element studi evalu biomechan effect differ attach posit maxillari molar intrus clear align treatment finit element analysi	D014087;D009968	T061;T074
36,348,392	effect onlin team base learn introduct medic ethic educ medic student medic colleg nepal pilot studi effect onlin class alway concern overcom opt activ learn strategi like team base learn tbl studi conduct find effect onlin tbl activ learn strategi also aim explor satisfact percept student toward tbl	D013337	T097
36,348,390	relationship menopaus syndrom gut microb gut microb close relat women health previous studi report gut microb premenopaus women differ postmenopaus women howev littl known relationship gut microbiota dysbiosi menopaus syndrom mps aim studi explor relationship mps gut microb	D064806;D000069196	T047;T046;T001;T007
36,348,388	ertapenem induc neurotox end stage renal diseas patient intermitt haemodialysi case report carbapenem induc neurotox unusu side effect seizur common report symptom among carbapenem imipenem cilastin classic associ sever neurotox side effect carbapenem main excret kidney half life signific increas patient chronic kidney diseas ckd therefor dose adjust necessari patient ertapenem associ neurotox increas report ckd patient rare seen patient recommend dose adjust	D007676;D020258;D051436	T047;T037
36,348,387	comparison surgic outcom without ologen collagen matrix augment xen gel stent implant compar surgic outcom postop complic without ologen collagen matrix augment xen gel stent implant	D020327;D005902	T047;T074
36,348,386	quantif lysosphingomyelin lysosphingomyelin screen acid sphingomyelinas defici acid sphingomyelinas defici asmd lysosom disord caus defici acid sphingomyelinas asm lead accumul sphingomyelin sm varieti cell type lysosphingomyelin lysosm de acetyl form sm shown biomark asmd tissu plasma dri blood spot dbs lysosphingomyelin lysosm carboxyl analogu lysosm high level lysosphingomyelin lysosm also shown asmd patient studi report util quantif lysosm lysosm dbs patient latin america asmd ultra perform liquid chromatographi tandem mass spectrometri uplc msms	D052536;D009542	T047
36,348,385	rucaparib recurr ovarian cancer real world experi rucaparib earli access programm spain geico studi rucaparib poli adp ribos polymeras inhibitor approv europ mainten therapi recurr platinum sensit pt ovarian cancer oc rucaparib access programm rap design provid earli access rucaparib mention indic well patient brca mutat pt platinum resist pt r oc therapeut altern	D010051;D000970	T121;T191;T109
36,348,384	longitudin function outcom late effect radiat follow treatment nasopharyng carcinoma secondari analysi prospect cohort studi studi object provid longitudin data upper aerodigest tract function late complic follow imrt nasopharyng carcinoma elucid factor might predict wors outcom hypothes despit advanc imrt radiat caus signific function declin late complic often progress aris year treatment larger radiat volum associ poorer outcom	D009303;D050397	T061;T191
36,348,383	propos feasibl classif common bile duct duplic base newli describ variant review exist literatur duplic common bile duct cbd extrem rare among anatom variat biliari tract system present septum within cbd accessori cbd studi report rare case duplic common bile duct combin congenit biliari dilatationw present rare case septum dilat biliari tract	D015529;D001659;D001662;D017734	T061;T019;T023
36,348,381	dietari divers primari schoolchildren south central cte divoir risk factor non communic diseas balanc nutrit import children physic cognit develop yet remain challeng mani part low middl incom countri lmic earli detect nutrit defici metabol syndrom school age children necessari prevent non communic diseas ncds later life studi aim obtain baselin data health nutrit status metabol marker ncds among primari schoolchildren cte divoir	D000073296;D011236;D008288;D000740	T047
36,348,380	interpret mechan type diabet mellitus base framework psychosomat medicin real world studi use bipolar disord bd control explor possibl development process impair glucos metabol rhythm	D003924;D011611;D011236	T047;T091
36,348,378	sever moral distress nurs systemat review meta analysi moral distress one import problem nurs face care patient various studi report frequenc sever moral distress nurs howev date comprehens studi show result research across world found therefor due import issu role health nurs patient lack general statist worldwid present studi conduct determin frequenc sever moral distress nurs systemat review meta analysi	D009014	T078
36,348,376	evalu diagnost manag agreement audiolog ent prospect inter rater agreement studi paediatr primari contact clinic ear nose throat ent primari contact model care use audiologist first triag point children refer ent middl ear hear concern shown reduc wait time improv ent surgic convers rate increas servic capac studi aim investig safeti qualiti model look agreement audiologist ent clinic decis method perform inter rater agreement studi diagnosi manag decis made audiologist ent children seen australian hospit ent primari contact servic examin natur pattern disagr	D001298	T091
36,348,373	evalu intern farm biosecur measur combin sow vaccin prevent influenza virus infect group due wean pig influenza virus iav import respiratori pathogen pig affect pig health well product zoonot potenti signific econom impact produc ultim goal maintain herd free iav due probabl iav introduct herd also desir herd immun virus studi evalu protocol combin sow vaccin implement intern biosecur practic pre wean period goal wean iav negat pig five iav posit breed herd vaccin twice week apart herd specif autogen vaccin subsequ week biosecur protocol maintain consist pig movement day age use nurs sow worker chang dispos glove litter worker step farrow crate daili disinfect tool materi use handl pig	D009976;D013553;D009980	T047;T005
36,348,372	effect earli home base strength sensori motor train total hip arthroplasti studi protocol multicent random control trial total hip arthroplasti tha effect allevi pain function deficit persist year follow surgeri regardless standard physiotherapi program signific addit muscular atrophi weak occur deficit strength serious advers consequ patient respect physic function mainten independ requir revis surgeri progress resist train rehabilit follow tha shown signific enhanc muscl strength function fundament principl progress overload exercis muscl becom stronger differ strength train protocol use differ time postop phase group individu practic major differ center base home base program without supervis primari object studi evalu whether earli postop home base strength train protocol improv patient function outcom month year follow surgeri secondari object feasibl present protocol elect tha patient safeti	D019644;D055070	T061
36,348,371	simultan measur size methyl chromosom qa dz repeat facioscapulohumer muscular dystrophi long read sequenc facioscapulohumer muscular dystrophi fshd autosom domin muscular disord character asymmetr muscl wast weak fshd subdivid two type fshd caus contract dz repeat chromosom q fshd caus mild contract dz repeat plus aberr hypomethyl mediat genet variant smchd dnmtb lrif genet diagnosi fshd challeng complex procedur requir	D020391	T047
36,348,370	alcohol use disord comorbid anxieti disord case report focus literatur review alcohol use disord aud anxieti disord anxd preval health concern clinic practic frequent co occur aud anxd compound one anoth concurr aud anxd pose challeng clinic manag approach treatment one disord may ineffect potenti counterproduct disord	D000437;D013375	T184;T048
36,348,369	depot buprenorphin opioid agonist therapi new south wale correct centr cost model daili liquid methadon sublingu buprenorphin naloxon primari opioid agonist treatment correct centr new south wale australia howev signific potenti divers patient daili administr resourc intens altern treatment form subcutan depot buprenorphin becam viabl option follow safeti trial unloc studi depot prepar demonstr advantag current treatment difficult divert requir fewer administr paper report result econom model staf cost medic administr compar depot buprenorphin methadon sublingu buprenorphin provis unloc trial facil	D002047;D009293	T121;T048;T109
36,348,368	dynamaed unifi model framework invas aed mosquito mosquito speci belong genus aed attract interest scientist public health offic capac transmit virus affect human speci brought outsid nativ rang mean trade tourism colonis new region thank uniqu combin eco physiolog trait consid mosquito physiolog behaviour trait understand predict popul dynam thus crucial step develop strategi mitig local densiti invas aed popul synthesis life cycl four invas aed speci ae aegypti ae albopictus ae japonicus ae koreicus singl multi scale stochast model framework code r packag dynamaed design stage base time discret stochast model driven temperatur photo period inter specif larval competit appli three differ spatial scale punctual local region spatial scale consid differ degre spatial complex data avail account activ passiv dispers mosquito speci well heterogen input temperatur data overarch aim provid flexibl open sourc user friend tool root updat knowledg speci biolog could appli manag invas aed popul well theoret ecolog inquiri	D000330	T204
36,348,367	associ bodi composit physic fit among chines medic student cross section studi studi examin associ bodi composit physic fit score among medic student shenyang china	D050177;D013337	T033;T097
36,348,366	defin impact platelet lymphocyt ratio patient surviv gastric neuroendocrin neoplasm retrospect cohort analysi gastric neuroendocrin neoplasm g nen rare heterogen neoplasm increas incid year convent prognost marker g nen remain limit could detect surgeri urgent need explor new prognost marker g nen patient studi aim investig prognost valu platelet lymphocyt ratio plr associ plr bodi mass index bmi patient gastric neuroendocrin neoplasm g nen	D018358;D013274	T191
36,348,365	agi grade guid chaiqin chengqi decoct treatment predict moder sever sever acut pancreat cap trial studi protocol randomis doubl blind placebo control parallel group pragmat clinic trial acut pancreat ap common digest diseas increas incid global without intern licenc pharmacolog therapi moder sever sever acut pancreat msapsap contribut predomin morbid mortal manag west china hospit decad use tradit chines medicin formula chaiqin chengqi decoct cqcqd current studi test whether earli administr cqcqd result improv clinic outcom predict msapsap patient	D010195;D004365	T121;T123;T047;T046
36,348,364	registr base assess femor torsion rotat osteotomi base contralater anatomi comput assist techniqu surgic treatment femor deform becom increas import state art deform assess contralater side use templat correct common repres normal anatomi contribut iter closest point icp algorithm use registr howev anatom section femur idiosyncrat featur allow consist deform assess icp algorithm unknown furthermor side side differ consid error quantif aim studi analyz influenc valu differ section femur assess femor deform base contralater anatomi	D014057;D001847	T060;T047

36,348,551

pah exposur associ oxid stress neurotransmitt level coal miner object learn investig polycycl aromat hydrocarbon pah explor associ pah exposur oxid stress neurotransmitt level coal miner method cross section survey conduct coal miner underground first line group underground auxiliari group surfac group april june level urinari monohydroxi pah metabolit oh pah oxid stress neurotransmitt blood determin linear regress model use evalu correl oh pah oxid stress neurotransmitt level mediat role oxid stress urinari oh pah neurotransmitt chang assess mediat analysi result level hydroxynaphthalen nap hydroxi uoren flu hydroxypyren ohp urin oh pah coal miner differ workplac signific differ h p level neurotransmitt hydroxytryptamin ht norepinephrin ne epinephrin e dopamin da acetylcholin ach acetylcholinesteras ach oxid stress malondialdehyd mda f p blood three group coal miner signific differ control potenti confound factor ne content negat correl flu level ach activ also negat correl ohp level ci p ci p posit correl found ach content hydroxyphenanthren phe level ach activ also posit correl nap level phe level ci p ci p ci p addit superoxid dismutas activ correl ohp level ach activ ci p ci p mediat analysi indic ohp level may direct affect ach activ p conclus level pah underground coal miner relat higher may lead chang neurotransmitt level mediat effect oxid stress observ

D011084

T109

36,348,550

effect pprb jnk signal pathway hydroquinon induc malign transform tk cell object investig cell cycl apoptosi hydroquinon hq induc malign transform tk cell relat regulatori mechan method tk cell expos moll hq htime week week experiment group tk cell treat phosphat buffer pbs week use control group march regulatori mechan research cell divid four group control group experiment group control inhibitor group experiment inhibitor group inhibitor group ad moll p cell cycl apoptosi detect flow cytometri protein express cell cycl relat protein jnk signal pathway protein detect western blot result flow cytometri show compar control group ratio cell gg phase experiment group signific decreas p ratio cell phase signific increas p western blot demonstr protein express p rb ser ef cyclin p p ser jnk p jnk thrtyr c jun p c jun ser p regul protein express rb p p p signific regul expos sp compar experiment group signific chang cell cycl distribut p apoptosi rate p experiment inhibitor group express c jun p protein regul express rb p protein regul experiment inhibitor group conclus hq induc tk cell malign transform cell cycl arrest phase pprb signal pathway inhibit jnk signal pathway activ howev activ jnk signal pathway may involv regul cell cycl

D006873;D020935

T121;T044;T109

36,348,511

algorithm instrument rapid spatial frequenc domain fluoresc diffus optic imag significancerapid estim depth margin fluoresc target buri tissu surfac could improv upon current imag guid surgeri techniqu tumor resectionaimw describ algorithm instrument permit rapid estim depth transvers margin fluoresc target turbid media work aim introduc experiment demonstr character methodologyapproachspati frequenc domain fluoresc diffus optic tomographi sfd fdot techniqu adapt rapid comput inexpens estim fluorophor target depth later margin algorithm util variat diffus fluoresc intens respect spatial modul frequenc comput target depth later margin determin via analyt invers data use depth inform obtain first step character method perform use fluoresc contrast target embed tissu simul phantomsresultssingl multipl target signific later size imag vari depth deep cm phantom data analysi show good depth sensit reconstruct transvers margin most within error true marginsconclusionsth studi suggest rapid sfd fdot approach could use resect surgeri broad first step rigor sfd fdot reconstruct experi permit evalu current limit

D041622;D025321

T060;T061

36,348,509

accur earli predict wound heal outcom burn injuri use wavelet shannon entropi terahertz time domain waveform significancesever burn injuri caus signific hypermetabol alter high dynam hard predict requir acut critic care clinic assess sever burn injuri high subject consist report inaccur therefor util imag modal crucial reach object accur burn assess modalityaimw describ non invas techniqu use terahertz time domain spectroscopi thz tds wavelet packet shannon entropi automat estim burn depth predict wound heal outcom thermal burn injuriesapproachw creat burn injuri differ sever grade two porcin model use scald contact method inflict use thz portabl handheld spectral reflect phasr scanner obtain vivo thz tds imag use energi shannon entropi ratio wavelet packet coeffici thz tds waveform day creat supervis support vector machin svm classif model histolog assess burn biopsi serv ground truthresultsw achiev accuraci rate predict wound heal outcom determin histolog measur epitheli rate day post burn induct use thz tds measur obtain day furthermor report accuraci rate automat diagnosi superfici partial thick deep partial thick full thick burn respect use multiclass svm modelconclusionsth thz phasr scanner promis robust high speed accur diagnost modal improv clinic triag burn manag

D012867;D055068

T022;T059

36,348,508

distinct clinicopatholog featur ovarian endometriosi long term exposur mifepriston mifepriston use treat endometriosi caus constel endometri alter studi investig effect long term mifepriston ovarian endometriosi

D004715;D010048;D010051

T047;T191

36,348,498

periop outcom uniport versus two port three port video assist thoracoscop surgeri lung cancer systemat review meta analysi uniport video assist thoracoscop surgeri vat appli wide treatment lung cancer recent year studi report uniport vat might provid better outcom multiport vat howev periop outcom uniport vat compar two port three port vat respect yet studi comprehens scale meta analysi studi compar periop efficaci among uniport two port three port vat

D020775;D008175

T061;T191

36,348,497

modif mesenchym stem cell cartilag target therapi osteoarthr oa chronic degen joint diseas character destruct articular cartilag sclerosi subchondr bone joint dysfunct pathogenesi attribut direct damag mechan destruct joint tissu mesenchym stem cell mscs suggest potenti strategi treatment oa shown therapeut effect oa howev specif fate mscs intraarticular inject includ cell attach prolifer differenti death still unclear guarante stem cell retain cartilag tissu enact repair direct home mscs import determin efficaci msc base cartilag repair recent studi reveal uniqu home capac mscs target modif improv abil promot tissu regener comprehens review home effect stem cell joint highlight progress toward target modif mscs futur develop target system acceler tissu regener benefit target tissu repair

D045164;D059630;D002358;D010003

T061;T047;T025;T024

36,348,496

develop test new applic measur motion cervic spine cervic myelopathi progress diseas earli detect treatment contribut prognosi evalu cervic intervertebr instabl simpl x ray use clinic set inform instabl import understand caus myelopathi evalu intervertebr instabl x ray complic reduc burden clinician system automat measur rang motion develop compar flex extend posit later view simpl x ray cervic spine accuraci system verifi comparison spine surgeon resid determin whether system could withstand actual use

D002574;D013118

T023;T047

36,348,495

evid anthocyanin betalain pigment genus hylocereus weak respond zhou bmc genom combin transcriptom metabolom analysi pitaya fruit unveil mechan under peel pulp color format publish bmc genom given evolutionari conserv anthocyanin biosynthesi pathway betalain pigment speci open idea speci anthocyanin betalain might exist howev absenc lc msms spectra appar lack biolog replic comparison authent standard find zhou bmc genom strong basi propos presenc anthocyanin betalain pigment pitaya addit analysi dataset indic misidentif import gene omiss key flavonoid anthocyanin synthesi gene an dfr final analysi rna seq dataset reveal correl anthocyanin biosynthesi gene express pigment status

D050858;D029421

T123;T002;T109

36,348,494

applic mapl comput strong fuzzi chromat polynomi fuzzi graph field graph theori mapl technic comput form use solv problem articl appli mapl find strong fuzzi chromat polynomi fuzzi graph relat moreov appli mapl obtain strong fuzzi chromat number fuzzi graph use strong fuzzi chromat polynomi

D031002

T002

36,348,492

indirect social contact intervent reduc mental health relat stigma low middl incom countri systemat review mental health relat stigma discrimin complex widespread issu negat effect numer aspect life peopl live experi mental health condit research show social contact best evid base intervent reduc stigma within context rapid develop remot technolog covid relat restrict face face contact aim paper categoris compar defin indirect social contact isc intervent reduc stigma discrimin mental health low middl incom countri lmic

D000086382;D001523

T047;T067;T048

36,348,491

assess left ventricular diastol function children hivaid attend tertiari health facil enugu nigeria doppler echocardiograph studi determin preval factor associ left ventricular diastol dysfunct children hivaid

D000163

T047

36,348,489

chronic rhinosinus associ chronic bronchiti five year follow telemark studi chronic rhinosinus crs associ generalis airway inflamm studi address relationship crs chronic bronchiti cb

D029481;D012852;D001249;D012220

T047

36,348,488

factor influenc adher antiretrovir therapi experi peopl live hiv healthcar provid sierra leon qualit studi antiretrovir therapi art primari mode treatment human immunodefici virus hiv slow diseas progress reduc spread infect hiv treatment also known requir high level adher achiev good treatment outcom viral load suppress sierra leon peopl live hiv plhiv non adher first year treatment understand reason behind high rate non adher perspect plhiv health worker critic develop strategi improv adher qualit studi root field public health servic identifi barrier facilit influenc adher antiretrovir treatment sierra leon method qualit studi design use depth interview four healthcar worker plhiv two district sierra leon freetown bo interview analyz use ground theori approach identifi emerg theme data

D055118;D015658

T033;T055;T081;T047

36,348,486

rare case report primari sjgren syndrom clinic characterist similar clipper primari sjgren syndrom pss autoimmun inflammatori diseas character dryness eye mouth mucous membran patient pss also present extraglandular manifest pulmonari kidney nervous system involv central nervous system cns manifest rare describ pss

D002493;D012859

T047

36,348,484

integr nutrit obes prevent consider institut invest decis regard food compani australian invest sector perspect grow recognit current food system unhealthi unsustain increas shift toward suppli market unhealthi ultra process food beverag larg food compani hold substanti power within food system present signific barrier progress address issu relat nutrit obes prevent institut investor pension fund play key role influenc corpor govern practic increas incorpor environment social govern esg consider within invest decis consid nutrit obes prevent institut investor present potenti avenu drive increas food industri account popul health impact studi investig view stakehold australian invest sector incorpor nutrit obes prevent consider within institut invest decis make regard food compani

D019649;D009752

T033;T057

36,348,483

predict exercis induc desatur copd patient without rest hypoxemia retrospect studi univers accept criterion assess exercis induc desatur eid purpos studi compar two method regular use determin eid copd patient well explor risk factor predictor relat eid

D029424;D011656;D004646

T047;T046

36,348,482

anxieti depress symptom albuminuria risk acut myocardi infarct norwegian hunt cohort studi studi suggest increas risk outcom peopl joint exposur share common causal pathway object studi determin risk incid acut myocardi infarct ami follow exposur albuminuria andor anxieti depress symptom

D000419;D009203

T033;T047

36,348,481

pattern chang obes indic cardiometabol risk factor diagnosi type diabet two decad follow tehran lipid glucos studi identifi pattern variat obes indic cardiometabol risk factor diagnosi type diabet could provid insight critic period drastic chang occur facilit target intervent prevent diabet therefor studi sought explor pattern chang obes indic cardiometabol risk factor diabet diagnosi

D003924;D002318

T047

36,348,480

later flow assay lfa diagnosi covid associ pulmonari aspergillosi capa singl center experi invas pulmonari aspergillosi ipa seen coronavirus covid report differ incid defin covid associ pulmonari aspergillosi capa detect galactomannan antigen import diagnost step diagnos ipa enzym link immunoassay elisa frequent use method later flow assay lfa increas use high sensit specif rapid diagnosi present studi aim compar sensit lfa elisa diagnosi capa covid patient follow hospit icu pandem icu p

D000086382;D055744;D055732

T047;T067

36,348,479

consum percept legal cannabi product canada repeat cross section studi consum percept legal cannabi product may drive willing purchas illeg legal market howev littl known topic current studi examin percept legal product among canadian cannabi consum year period follow feder legal non medic cannabi

D002188

T121;T002;T167;T109

36,348,478

comparison machin learn model bluetongu risk predict seropreval studi small rumin bluetongu bt diseas concern anim breeder question mind whether predict risk diseas occur main object studi enhanc accuraci bt risk predict reli machin learn ml approach help fulfil inquiri sever risk factor bt affect occurr magnitud anim infect virus report global addit risk factor sex age speci season uneven affect anim health welfar therefor seropreval studi data appar healthi anim sheep goat five differ provinc egypt use analyz compar perform algorithm predict bt risk

D001819;D015511;D012757

T047

36,348,477

periop transcutan electr acupoint stimul ptea pain manag major spinal surgeri patient lumbar disc herniat seen patient lumbar back pain common spine disord demand surgic correct spinal surgeri one effect manag patient howev current surgic techniqu still present complic chronic pain patient underw lumbar surgeri signific impact patient qualiti life research studi shown transcutan electr acupoint stimul tea may reduc cumul dosag intraop anesthet well postop pain medic patient

D015669;D059408

T061;T029

36,348,476

phase iiiii trial hyperimmun anti covid intraven immunoglobulin c ivig therapi sever covid patient studi protocol random control trial covid pose global health challeng million cumul case million cumul death report till januari world health organ sever potenti treatment treat covid clinic trial includ antivir steroid immunomodul non specif ivig monoclon antibodi passiv immun convalesc plasma need produc anti covid ivig therapi must continu alongsid current treatment modal consid virus still mutat variant concern context present studi exploit pool diversifi convalesc plasma collect recov covid patient propos hyperimmun anti covid intraven immunoglobulin c ivig therapi would abl counter new infecti covid variant neutral virus particl success outcom phase iii clinic trial c ivig current studi aim evalu safeti efficaci singl low dose c ivig sever covid patient phase iiiii clinic trial

D000086382;D011024;D018352

T047;T067

36,348,474

chang prevent behaviour covid vaccin thailand cross section studi protect behaviour eg mask wear handwash avoid social gather mass vaccin effect way control coronavirus diseas covid pandem previous studi found peopl get vaccin may chang protect behaviour thai govern endors sever mix match vaccin regimen elimin insuffici vaccin brand studi aim determin level protect behaviour chang covid vaccin relationship various vaccin regimen thailand

D000086382

T047;T067

36,348,473

effect relat mechan alpha adrenerg receptor inhibitor phentolamin rabbit model acut pulmonari embol combin shock observ effect mechan alpha adrenerg receptor inhibitor phentolamin ptl rabbit model acut pulmonari embol ape combin shock

D011655;D012769;D015186

T047;T046;T015

36,348,471

lineag abund estim sar cov wastewat use transcriptom quantif techniqu effect monitor spread sar cov mutant essenti effort counter ongo pandem predict lineag abund wastewat howev technic challeng show sequenc sar cov rna wastewat appli algorithm initi use transcriptom quantif estim lineag abund wastewat sampl find high variabl signal among individu sampl overal trend match observ sequenc clinic sampl thus clinic sequenc remain sensit techniqu popul surveil wastewat sequenc use monitor trend mutant preval situat clinic sequenc unavail

D000086402;D000086382

T005;T067;T047

36,348,470

depress associ younger age femal sex obes smoke physic inact patient newli diagnos type diabet swedish multicentr cross section studi depress risk factor type diabet td cardiovascular diseas cvd aim explor preval depress anxieti antidepress use obes hemoglobin ac mmolmol life style factor pre exist cvd patient newli diagnos td explor associ depress compar swedish general popul data

D003924;D002318

T047

36,348,468

mix liver kidney transcriptom dataset darevskia valentini rock lizard studi perform frame bigger studi dedic genom transcriptom parthenogenesi vertebr among vertebr oblig parthenogenesi first describ lizard genus darevskia genus found parthenogenet speci origin via interspecif hybrid remain unknown genet genom factor play key role generat parthenogenet organ compar genom transcriptom analysi parthenogen parent speci may elucid problem darevskia valentini patern speci four seven parthenogen genus promot particular import speci generat parthenogenet form

D008116

T014

36,348,467

prepar character vitro cytotox nanoliposom load anti tubercular drug tgf sirna improv spinal tuberculosi therapi tuberculosi tb repres bacteri infect affect mani individu year potenti lead death overexpress transform growth factor tgf primari immunomodulatori function human tuberculosi work aim develop nanoliposom facilit deliveri anti tubercular product thp deriv human macrophag mycobacterium host cell evalu drug effici well effect tgf specif short interf rna sirna deliveri system employ nanoliposom

D053773;D014399

T123;T047;T121;T116

36,348,466

advers emot resili among syrian refuge netherland syrian refuge compris vast major refuge netherland although research carri factor promot refuge resili empir studi resili syrian refuge

D012036

T098

36,348,465

rage display sex specif differ obes induc adipos tissu insulin resist receptor advanc glycat end product rage play import role obes associ insulin sensit also previous report rage defici improv insulin resist obes induc adipos tissu current studi aim elucid sex specif mechan rage defici adipos tissu metabol regul system glucos homeostasi

D007333

T046

36,348,463

decellular bovin ovarian nich restor function cumulus endotheli cell recent decellular techniqu introduc one tissu engin procedur treatment various defici aim assess dynam activ ccs huvec within decellular bovin ovarian tissu transplant subcutan rat ovarian tissu decellular use cocktail consist differ chemic effici decellular assess use hematoxylin eosin dapi stain cell surviv evalu use ldh leakag assay thereaft decellular sampl recellular use huvec ccs encapsul insid algin gelatin hydrogel transplant subcutan rat exist cd estrogen posit cell assess use immunohistochemistri stain

D005109;D042783

T025;T024

36,348,461

evolut function development dynam pseudogen mammal pseudogen excel marker genom evolut emerg crucial regul develop diseas especi cancer howev systemat function character evolut pseudogen remain larg unexplor

D011544;D009369

T191;T028

36,348,460

inclus progress criteria extern randomis pilot trial cross section studi fund applic submit nihr research patient benefit programm extern randomis pilot trial aim assess whether futur definit randomis control trial rct feasibl pre specifi progress criteria help guid interpret pilot trial find decid whether definit trial conduct aim examin research report plan assess progress criteria extern pilot trial fund applic submit nihr research patient benefit programm

D012107

T062;T096;T170;T081;T169

36,348,459

novel homozyg mutat trappc gene caus autosom recess non syndrom intellectu disabl etiolog intellectu disabl divers includ genet environment factor genet caus intellectu disabl rang chromosom aberr singl gene disord trappc gene report caus autosom recess form intellectu disabl patient consanguin non consanguin famili around world

D008607;D008831

T019;T047;T048

36,348,457

natur killer cell clinic develop non engin engin combin therapi natur killer nk cell uniqu immun effector abl kill cancer cell direct recognit surfac ligand without prior sensit allogen nk transfer high valuabl treatment option cancer recent emerg hundr clinic trial pave way final achiev market author advantag nk cell therapi includ use allogen cell sourc shelf avail risk graft versus host diseas gvhd allogen nk cell therapi reach clinic stage ex vivo expand differenti non engin cell chimer antigen receptor car engin cd engin product combin therapi antibodi prime agent drug review summar recent clinic status allogen nk cell base therapi treatment hematolog solid tumor discuss main characterist differ cell sourc use nk product develop use cell manufactur process engin method strategi adopt genet modifi product chosen approach combin therapi compar analysi nk base non engin engin combin therapi present examin choic made product develop regard nk cell sourc target tumor indic solid hematolog cancer clinic trial outcom discuss avail assess comparison preclin data regulatori challeng product approv review highlight lack specif requir standard product addit competit landscap busi field present review offer comprehens overview effort driven biotech pharmaceut compani academ center bring nk cell therapi pivot clinic trial stage market author

D000076962;D009369;D019337

T129;T191;T116;T192

36,348,455

cladribin treatment improv cortic network function mous model autoimmun encephalomyel cladribin synthet purin analogu interfer dna synthesi repair next disrupt cellular prolifer activ divid lymphocyt compound approv treatment multipl sclerosi ms cladribin cross blood brain barrier suggest potenti effect central nervous system cns resid cell explor compart specif immunosuppress well potenti direct neuroprotect effect oral cladribin treatment experiment autoimmun encephalomyel eae mice

D004681;D018696;D004679

T121;T047;T050;T169

36,348,454

icu bridg program volunt bridg medicin peopl togeth intens care unit icu emot tax environ patient famili member increas risk long term physic psycholog consequ critic ill known collect post intens care syndrom pic environment strain lead high incid staff turnov burnout

D007362;D016638

T047;T073;T093

36,348,453

intensifi tuberculosi treatment reduc mortal hiv infect uninfect patient tuberculosi mening intens tbm studi protocol phase iii random control trial tubercul mening tbm lethal disabl form tuberculosi tb particular sub saharan africa current anti tb treatment poor effect sinc tbm mortal reach hiv negat patient hiv co infect patient reduc tbm induc morbid mortal intens tbm trial evalu two intervent hiv infect uninfect patient anti tb treatment intensif use oral high dose rifampicin mgkg daili linezolid mg daili mg daili first week anti tb treatment use adjunct aspirin mg daili

D014390;D015658

T047

36,348,452

respiratori ill virus infect special emphasi covid virus emerg pose challeng treatment option uniqu would know complet henc mani virus caus high morbid mortal long time despit larg divers virus share common characterist infect least differ respiratori born virus report belong various virus taxonom famili mani virus multipli caus damag upper lower respiratori tract descript virus comparison concern epidemiolog molecular characterist diseas manifest diagnosi treatment lack inform help diagnos differenti formul control measur faster lead caus acut ill worldwid acut respiratori infect ari respons near million death everi year most young children infant lower respiratori tract infect fourth common caus death global non infecti chronic condit review aim present characterist differ virus caus respiratori infect highlight uniqu sar cov expect review help understand similar differ among close relat virus caus respiratori infect formul specif prevent control measur

D000086382;D012141;D014780

T047;T005;T067

36,348,446

characterist cost electr scooter injuri helsinki retrospect cohort studi incid electr scooter e scooter injuri increas drastic numer countri widespread avail share e scooter econom impact societi broader perspect studi aim estim incid e scooter injuri describ injuri pattern estim cost e scooter injuri

D006260;D006259

T073;T037

36,348,445

success breastfeed follow level ii nicu stay qatar longitudin studi exclus breastfeed essenti need mother newborn babi cultur practic employ demand signific influenc feed practic associ neonat intens care unit nicu admiss breastfeed outcom variabl data qatar middl east particular limit henc studi aim estim rate breastfeed time nicu discharg rate success breastfeed nicu discharg qatar well babi follow up

D001942;D007363

T073;T055;T040;T093;T058

36,348,444

case primari optic pathway demyelin caus oncocyt oligodendrogliopathi unknown origin report case year old woman present acut onset dizzi gait dysbal blur vision magnet reson imag includ tesla tesla imag reveal hyperintens hypointens non contrast enhanc lesion strict confin white matter affect right optic radiat extens ophthalmolog examin yield mild quadrantanopia sign optic neuropathi lesion biopsi neuropatholog evalu reveal demyelin lesion mark tissu vacuol granular myelin disintegr accompani mild cell infiltr notabl absenc myelin uptak macrophag oligodendrocyt strike enlarg display oncocyt characterist show cytoplasm accumul mitochondria mild abnorm morpholog electron microscopi diagnosi multipl sclerosi exclud hard diseas variant leber hereditari optic neuropathi suspect howev neither pcr relev mutat whole exom sequenc yield known pathogenet mutat patient genom present pattern demyelin tissu injuri unknown etiolog oncocyt chang oligodendrocyt lack adequ phagocyt respons macrophag best knowledg describ

D029242;D009103;D066127

T047;T024;T023

36,348,440

review applic exposom paradigm unveil environment determin age relat diseas age relat diseas account almost half diseas among adult worldwid incid substanti affect exposom sum exogen endogen environment exposur human bodi respons exposur throughout entir lifespan herein perform comprehens review epidemiolog literatur determin key element exposom affect develop age relat diseas role age hallmark process find exposur assess previous age studi use reductionist approach wherebi effect singl environment factor specif class environment factor develop age relat diseas examin lack holist unbias understand effect multipl environment factor develop age relat diseas address propos sever research strategi base exposom framework could advanc understand particular mechanist perspect environment factor affect develop age relat diseas discuss statist method method use exposom wide associ studi particular focus multiom technolog also address futur challeng opportun realm multidisciplinari approach genom exposom epidemiolog furthermor provid perspect precis public health servic vulner popul public communic integr risk exposur inform bench bedsid translat research age relat diseas

D000081413

T058

36,348,439

gap sexual transmit infect screen among youth live hiv alabama gap sexual transmit infect sti test lead poor health outcom due untreat ill among youth live hiv ylhiv thus object studi examin sti test behavior outcom among sampl ylhiv southern unit state clinic record ylhiv receiv hiv care alabama evalu receipt sti test gonorrhea chlamydia syphili preval posit test result factor associ test outcom clinic visit

D013587;D015658;D012749;D006069;D002690

T047

36,348,437

express ki p relat hpv squamous cell carcinoma extern auditori canal squamous cell carcinoma extern auditori canal eacscc uncommon tumor respons head neck malign although remark research evid exhibit high risk human papillomavirus hpv account consider head neck malign role pathogenesi eacscc yet determin

D030361;D002294;D006258

T047;T191

36,348,436

anti leucin rich glioma inactiv enceph two case report review literatur anti leucin rich glioma inactiv enceph newli emerg entiti character frequent faciobrachi dyston seizur wide spectrum subacut clinic symptom seizur type mood behavior chang memori loss awar differenti diagnosi psychogen nonepilept seizur mesial tempor limbic structur basal ganglia common involv region

D020363;D004660;D005910

T047;T191

36,348,435

ventricular arrhythmia burden patient implant cardiovert defibril remot patient monitor differ time interv covid pandem current studi investig whether chang patient care time covid pandem especi reduct person visit would result deterior arrhythm clinic condit patient implant cardiovert defibril icd remot patient monitor

D017147;D000086382

T047;T074;T067

36,348,433

molecular characterist norovirus sporad outbreak case acut gastroenter sewag sichuan china norovirus high divers constant surveil essenti prevent control norovirus gastroenter

D029322;D017250;D005759

T005;T047

36,348,432

death human cytomegalovirus infect girl congenit thymic dysplasia report case girl congenit thymic dysplasia refractori dissemin human cytomegalovirus cmv infect diagnos autopsi addit diagnos cell lymphopenia immunodefici receiv antivir therapi ganciclovir gcv valganciclovir v gcv enhanc foscarnet cmv viral load vl monitor elev retin interstiti pneumonia hepat phenotyp cell lymphopenia uncertain limit altern therapi whole exom sequenc wes lymphocyt subset panel autopsi girl die progress respiratori failur septic shock ten month age sever dissemin cmv infect typic develop infant primari matern infect occur earlier gestat peopl weaken host immun system individu cmv infect initi immunodefici associ poor prognosi similar patient secondari immunodefici case describ difficult treatment prognosi cmv infect patient congenit immunodefici highlight import earli aggress anti cmv antivir therapi immunodefici vl monitor drug resist role cell cmv infect

D003586;D008231

T047

36,348,431

high preval resist third generat cephalosporin detect among clinic isol sentinel healthcar facil lago nigeria antimicrobi resist amr bacteri pathogen worldwid concern demand immedi attent inform amr origin high incom countri littl known burden africa particular nigeria use four sentinel site general hospit lago state studi sought estim burden amr

D002439;D013203

T047;T195;T109

36,348,430

field test new icd code system method earli experi icd beta version beta version intern classif diseas th revis mms icd need test field test involv real world applic new code examin usabl describ creat dataset character usabl icd code set coder compar icd icd ca canadian modif refer standard dataset diagnos real world usabl encompass code select time code complet inpati chart use icd compar icd ca

D038801;D006761

T170;T073;T093

36,348,429

profession wellb turnov intent among child therapist comparison therapist train untrain trauma focus cognit behavior therapi poor profession wellb job turnov challeng child mental health clinic despit increas interest implement evid base practic ebp mental health servic littl known use ebp may influenc therapist profession wellb turnov intent investig compar averag level compass satisfact burnout secondari traumat stress turnov intent therapist train ebp trauma focus cognit behavior therapi tf cbt untrain therapist also explor preval associ person organiz outcom

D000068376;D002055;D015928

T061;T048

36,348,427

evalu first aid skill train systemat review abl help save live layperson recommend undergo first aid train aim review explor varieti element measur system assess effect first aid train differ aspect first aid skill includ practic skill knowledg emot perspect

D005392;D016887

T061

36,348,426

sagitt intervertebr rotat motion deep learn base measur flexion neutral extens cervic later radiograph analysi sagitt intervertebr rotat motion sirm provid import inform evalu cervic diseas deep learn wide use spinal paramet measur howev investig spinal motion analysi purpos studi develop deep learn base model fulli autom measur sirm base flexion neutral extens cervic later radiograph evalu applic flexion extens fe flexion neutral fn neutral extens ne motion analysi

D002574;D000077321

T023;T066

36,348,424

effect shunt surgeri corticospin excit idiopath normal pressur hydrocephalus transcrani magnet stimul studi idiopath normal pressur hydrocephalus inph multifactori diseas present classic symptom triad cognit declin gait disturb urinari incontin symptom allevi shunt surgeri etiolog symptom remain unclear navig transcrani magnet stimul ntms appli character corticospin excit cortic motor function shunt surgeri order elucid pathophysiolog inph also aim determin whether ntms could appli predict tool pre surgic work inph

D006850;D009044

T047;T029;T023

36,348,423

longitudin trend produc purchas behavior descript studi transact level data loyalti card household household food purchas hfp pathway communiti food environ food avail household consumpt hfp data emerg altern monitor popul dietari trend time paper investig use loyalti card dataset unexplor sourc continu collect hfp data describ tempor trend household produc purchas

D003258;D005191

T098;T080;T099;T062;T079;T054;T102

36,348,422

effect mhealth base exercis insulin sensit patient hepatocellular carcinoma insulin resist mish protocol random control trial import insulin resist gain increas attent play import role carcinogenesi hepatocellular carcinoma hcc although exercis import intervent lower insulin resist easi hcc patient maintain high complianc appropri exercis mobil health mhealth wearabl devic solut carri adjust supervis exercis normal insulin resist patient hcc develop hcc specif applic equip patient center exercis paper present random control trial protocol compar intervent group control group determin whether mhealth base exercis effect normal insulin sensit hcc patient insulin resist anticanc treatment

D007333;D006528;D017216;D008113

T058;T046;T191

36,348,421

induct mechan cigarett smoke compon cscs dyslipidemia hepat steatosi rat purpos studi explor effect cigarett smoke compon csc exposur serum lipid level rat under molecular mechan

D000073865;D005234;D050171;D035683

T123;T055;T114;T047;T046

36,348,420

laparoscop versus open distal gastrectomi elder patient advanc gastric cancer retrospect compar studi laparoscop radic distal gastrectomi ldg frequent perform local advanc distal gastric cancer agc open distal gastrectomi odg howev benefit ldg elder agc patient agc lap remain unclear

D013274;D010535

T060;T191;T061

36,348,418

childhood diabet mellitus earli onset kidney diseas later life nationwid popul base match cohort studi empir evid remain inconclus associ diabet mellitus dm children earli onset kidney diseas later life littl known effect dm type ie type diabet tdm type diabet tdm childhood type specif kidney diseas aim evalu associ childhood dm overal type specif earli onset kidney diseas later life

D003922;D003924;D007674;D051437

T047

36,348,417

swedish trial embol middl mening arteri versus surgic evacu chronic subdur hematoma swemma nation month multi center random control superior trial parallel group assign open treatment alloc blind clinic outcom assess chronic subdur hematoma csdh one common neurosurg disord incid rise routin treatment neurosurg hematoma evacu associ recurr rate recent year endovascular embol middl mening arteri emma garner much attent due recurr rate low sever random control trial plan ongo trial convent neurosurg treatment without adjunct endovascular embol compar propos trial aim conduct head head comparison neurosurg endovascular treatment stand alon treatment

D020200

T046

36,348,415

genom wide profil retrovir dna integr effect clinic pre infus car cell product clinic car cell therapi use integr vector system repres promis approach treatment hematolog malign lentivir retrovir vector common use vector manufactur process howev integr pattern viral vector subsequ effect car cell product still unclear

D016086;D012190

T005

36,348,414

sex differ medial prefront cortic glutam system dysregul prefront cortex under varieti psychiatr ill includ substanc use disord depress anxieti despit establish sex differ preval present ill neural mechan drive differ larg unexplor investig potenti sex differ glutamaterg transmiss within medial prefront cortex mpfc goal experi determin baselin sex differ transmiss within region may underli sex differ diseas involv dysregul prefront cortex

D018698;D012727

T123;T032;T121;T116

36,348,413

molecular test deliv person chemotherapi recommend risk undertreat adjuv set cancer treatment de escal strategi goal omit minim treatment patient without compromis outcom histor elig adjuv treatment sole reli patient clinic tumor patholog characterist turn centuri base new biolog understand molecular base strategi test sometim implement

D001943;D003110

T191

36,348,411

neighborhood environment factor link hospit older peopl viral lower respiratori tract infect spain case crossov studi lower respiratori tract viral infect lrti signific caus morbid mortal older peopl worldwid analyz associ short term exposur environment factor climat factor outdoor air pollut hospit admiss viral lrti diagnosi older adult

D000393;D000397;D012141

T131;T047;T069;T080

36,348,410

drive assess preclin alzheim diseas progress date path forward chang drive behaviour may start preclin stage alzheim diseas ad under ad biolog process begun presenc cognit normal summar emerg evid suggest preclin ad may impact everyday drive behaviour main increas evid link drive perform behaviour ad biomark cognit intact older adult studi found subtl yet detect differ drive associ ad biomark status among cognit intact older adult

D000544

T047;T048

36,348,409

improv malaria surveil electron integr diseas surveil respons eidsr system mainland tanzania tanzania made remark progress reduc malaria burden aim transit malaria control sub nation elimin electron week month report platform use district health inform system dhis introduc week report implement mobil phone base integr diseas surveil respons eidsr platform progress scale public privat health facil studi describ roll larg scale implement eidsr compar consist week eidsr month dhis malaria indic data report includ assess use malaria outbreak detect case base surveil cbs low transmiss area

D008288;D063005

T047;T170

36,348,408

nkd correl occurr progress prognosi thyroid carcinoma thyroid carcinoma thca preval type tumor endocrin system nkd increas evidenc play crucial role mani cancer except thca herein aim explor potenti role nkd thca

D002352;D013964

T123;T191;T116

36,348,405

promot synthet degrad activ stat parp inhibit role poli adp ribosyl ation calpain autophagi report parp regul gene whose product crucial asthma part control stat integr specul calpain depend mechan wish deciph parp stat relationship context intracellular traffick promot occup transcript factor target gene integr presenc calpain connect autophagi

D000074747;D011065

T126;T116;T044

36,348,401

complianc hand hygien practic among nurs staff secondari healthcar hospit kuwait hand hygien hh among healthcar worker especi nurs main prevent measur control healthcar associ infect complianc hand hygien cwhh remain low various set includ kuwait studi aim assess knowledg attitud toward cwhh among nurs staff secondari care hospit kuwait

D063373;D003428;D009740

T055;T047;T097

36,348,400

prognost potenti liver injuri patient dilat cardiomyopathi retrospect studi liver injuri li frequent observ patient dilat cardiomyopathi dcm wherea prognost valu remain blurri attempt apprais prognost effect li patient dcm

D002311

T047

36,348,398

oral manifest associ inflammatori bowel diseas earli endoscop find patient spondyloarthr spondyloarthr spa group autoinflammatori disord primari extra articular manifest inflammatori bowel diseas ibd oral caviti part gastrointestin tract signific compromis ibd mani case first site clinic manifest ibd studi aim identifi chang oral mucosa associ onset ibd associ endoscopichistolog find

D013281;D025241;D015212;D019226;D005891;D012216

T047

36,348,397

investig job satisfact amongst voluntari counsel test center health center iran job satisfact person feel job personnel good feel work destroy plan intent unintent present research aim investig compar job satisfact employe therapist voluntari counsel test center versus health center provinc iran

D007588;D017132

T082;T041

36,348,396

nonunion humer medial condyl fractur caus excess function exercis case report review literatur medial epicondyl fractur one common humerus fractur humer medial condyl fractur hmcf rare nonunion medial humer condyl fractur due function exercis less common

D004551;D006810;D005599

T046;T037;T030

36,348,395

vector born pathogen potenti relev dissemin reloc cat larg popul unown cat constitut anim welfar ecolog societ public health issu worldwid reloc home current carri mani part world intent reliev suffer social problem contribut ethic human popul control cat popul understand individu cat lifestyl diseas status veterinari team profession work cat chariti help prevent sever cat stress spread felin pathogen especi vector born pathogen overlook cat articl discuss issu reloc home unown cat global perspect also review zoonot non zoonot infecti agent cat give list practic recommend veterinari team profession deal home cat final present consensus statement consolid th symposium companion vector born diseas cvbd world forum ultim help veterinari team profession understand problem role help prevent manag vector born pathogen reloc cat

D004199;D002371

T047;T008

36,348,394

effect attach posit molar intrus clear align finit element studi evalu biomechan effect differ attach posit maxillari molar intrus clear align treatment finit element analysi

D014087;D009968

T061;T074

36,348,392

effect onlin team base learn introduct medic ethic educ medic student medic colleg nepal pilot studi effect onlin class alway concern overcom opt activ learn strategi like team base learn tbl studi conduct find effect onlin tbl activ learn strategi also aim explor satisfact percept student toward tbl

D013337

T097

36,348,390

relationship menopaus syndrom gut microb gut microb close relat women health previous studi report gut microb premenopaus women differ postmenopaus women howev littl known relationship gut microbiota dysbiosi menopaus syndrom mps aim studi explor relationship mps gut microb

D064806;D000069196

T047;T046;T001;T007

36,348,388

ertapenem induc neurotox end stage renal diseas patient intermitt haemodialysi case report carbapenem induc neurotox unusu side effect seizur common report symptom among carbapenem imipenem cilastin classic associ sever neurotox side effect carbapenem main excret kidney half life signific increas patient chronic kidney diseas ckd therefor dose adjust necessari patient ertapenem associ neurotox increas report ckd patient rare seen patient recommend dose adjust

D007676;D020258;D051436

T047;T037

36,348,387

comparison surgic outcom without ologen collagen matrix augment xen gel stent implant compar surgic outcom postop complic without ologen collagen matrix augment xen gel stent implant

D020327;D005902

T047;T074

36,348,386

quantif lysosphingomyelin lysosphingomyelin screen acid sphingomyelinas defici acid sphingomyelinas defici asmd lysosom disord caus defici acid sphingomyelinas asm lead accumul sphingomyelin sm varieti cell type lysosphingomyelin lysosm de acetyl form sm shown biomark asmd tissu plasma dri blood spot dbs lysosphingomyelin lysosm carboxyl analogu lysosm high level lysosphingomyelin lysosm also shown asmd patient studi report util quantif lysosm lysosm dbs patient latin america asmd ultra perform liquid chromatographi tandem mass spectrometri uplc msms

D052536;D009542

T047

36,348,385

rucaparib recurr ovarian cancer real world experi rucaparib earli access programm spain geico studi rucaparib poli adp ribos polymeras inhibitor approv europ mainten therapi recurr platinum sensit pt ovarian cancer oc rucaparib access programm rap design provid earli access rucaparib mention indic well patient brca mutat pt platinum resist pt r oc therapeut altern

D010051;D000970

T121;T191;T109

36,348,384

longitudin function outcom late effect radiat follow treatment nasopharyng carcinoma secondari analysi prospect cohort studi studi object provid longitudin data upper aerodigest tract function late complic follow imrt nasopharyng carcinoma elucid factor might predict wors outcom hypothes despit advanc imrt radiat caus signific function declin late complic often progress aris year treatment larger radiat volum associ poorer outcom

D009303;D050397

T061;T191

36,348,383

propos feasibl classif common bile duct duplic base newli describ variant review exist literatur duplic common bile duct cbd extrem rare among anatom variat biliari tract system present septum within cbd accessori cbd studi report rare case duplic common bile duct combin congenit biliari dilatationw present rare case septum dilat biliari tract

D015529;D001659;D001662;D017734

T061;T019;T023

36,348,381

dietari divers primari schoolchildren south central cte divoir risk factor non communic diseas balanc nutrit import children physic cognit develop yet remain challeng mani part low middl incom countri lmic earli detect nutrit defici metabol syndrom school age children necessari prevent non communic diseas ncds later life studi aim obtain baselin data health nutrit status metabol marker ncds among primari schoolchildren cte divoir

D000073296;D011236;D008288;D000740

T047

36,348,380

interpret mechan type diabet mellitus base framework psychosomat medicin real world studi use bipolar disord bd control explor possibl development process impair glucos metabol rhythm

D003924;D011611;D011236

T047;T091

36,348,378

sever moral distress nurs systemat review meta analysi moral distress one import problem nurs face care patient various studi report frequenc sever moral distress nurs howev date comprehens studi show result research across world found therefor due import issu role health nurs patient lack general statist worldwid present studi conduct determin frequenc sever moral distress nurs systemat review meta analysi

D009014

T078

36,348,376

evalu diagnost manag agreement audiolog ent prospect inter rater agreement studi paediatr primari contact clinic ear nose throat ent primari contact model care use audiologist first triag point children refer ent middl ear hear concern shown reduc wait time improv ent surgic convers rate increas servic capac studi aim investig safeti qualiti model look agreement audiologist ent clinic decis method perform inter rater agreement studi diagnosi manag decis made audiologist ent children seen australian hospit ent primari contact servic examin natur pattern disagr

D001298

T091

36,348,373

evalu intern farm biosecur measur combin sow vaccin prevent influenza virus infect group due wean pig influenza virus iav import respiratori pathogen pig affect pig health well product zoonot potenti signific econom impact produc ultim goal maintain herd free iav due probabl iav introduct herd also desir herd immun virus studi evalu protocol combin sow vaccin implement intern biosecur practic pre wean period goal wean iav negat pig five iav posit breed herd vaccin twice week apart herd specif autogen vaccin subsequ week biosecur protocol maintain consist pig movement day age use nurs sow worker chang dispos glove litter worker step farrow crate daili disinfect tool materi use handl pig

D009976;D013553;D009980

T047;T005

36,348,372

effect earli home base strength sensori motor train total hip arthroplasti studi protocol multicent random control trial total hip arthroplasti tha effect allevi pain function deficit persist year follow surgeri regardless standard physiotherapi program signific addit muscular atrophi weak occur deficit strength serious advers consequ patient respect physic function mainten independ requir revis surgeri progress resist train rehabilit follow tha shown signific enhanc muscl strength function fundament principl progress overload exercis muscl becom stronger differ strength train protocol use differ time postop phase group individu practic major differ center base home base program without supervis primari object studi evalu whether earli postop home base strength train protocol improv patient function outcom month year follow surgeri secondari object feasibl present protocol elect tha patient safeti

D019644;D055070

T061

36,348,371

simultan measur size methyl chromosom qa dz repeat facioscapulohumer muscular dystrophi long read sequenc facioscapulohumer muscular dystrophi fshd autosom domin muscular disord character asymmetr muscl wast weak fshd subdivid two type fshd caus contract dz repeat chromosom q fshd caus mild contract dz repeat plus aberr hypomethyl mediat genet variant smchd dnmtb lrif genet diagnosi fshd challeng complex procedur requir

D020391

T047

36,348,370

alcohol use disord comorbid anxieti disord case report focus literatur review alcohol use disord aud anxieti disord anxd preval health concern clinic practic frequent co occur aud anxd compound one anoth concurr aud anxd pose challeng clinic manag approach treatment one disord may ineffect potenti counterproduct disord

D000437;D013375

T184;T048

36,348,369

depot buprenorphin opioid agonist therapi new south wale correct centr cost model daili liquid methadon sublingu buprenorphin naloxon primari opioid agonist treatment correct centr new south wale australia howev signific potenti divers patient daili administr resourc intens altern treatment form subcutan depot buprenorphin becam viabl option follow safeti trial unloc studi depot prepar demonstr advantag current treatment difficult divert requir fewer administr paper report result econom model staf cost medic administr compar depot buprenorphin methadon sublingu buprenorphin provis unloc trial facil

D002047;D009293

T121;T048;T109

36,348,368

dynamaed unifi model framework invas aed mosquito mosquito speci belong genus aed attract interest scientist public health offic capac transmit virus affect human speci brought outsid nativ rang mean trade tourism colonis new region thank uniqu combin eco physiolog trait consid mosquito physiolog behaviour trait understand predict popul dynam thus crucial step develop strategi mitig local densiti invas aed popul synthesis life cycl four invas aed speci ae aegypti ae albopictus ae japonicus ae koreicus singl multi scale stochast model framework code r packag dynamaed design stage base time discret stochast model driven temperatur photo period inter specif larval competit appli three differ spatial scale punctual local region spatial scale consid differ degre spatial complex data avail account activ passiv dispers mosquito speci well heterogen input temperatur data overarch aim provid flexibl open sourc user friend tool root updat knowledg speci biolog could appli manag invas aed popul well theoret ecolog inquiri

D000330

T204

36,348,367

associ bodi composit physic fit among chines medic student cross section studi studi examin associ bodi composit physic fit score among medic student shenyang china

D050177;D013337

T033;T097

36,348,366

defin impact platelet lymphocyt ratio patient surviv gastric neuroendocrin neoplasm retrospect cohort analysi gastric neuroendocrin neoplasm g nen rare heterogen neoplasm increas incid year convent prognost marker g nen remain limit could detect surgeri urgent need explor new prognost marker g nen patient studi aim investig prognost valu platelet lymphocyt ratio plr associ plr bodi mass index bmi patient gastric neuroendocrin neoplasm g nen

D018358;D013274

T191

36,348,365

agi grade guid chaiqin chengqi decoct treatment predict moder sever sever acut pancreat cap trial studi protocol randomis doubl blind placebo control parallel group pragmat clinic trial acut pancreat ap common digest diseas increas incid global without intern licenc pharmacolog therapi moder sever sever acut pancreat msapsap contribut predomin morbid mortal manag west china hospit decad use tradit chines medicin formula chaiqin chengqi decoct cqcqd current studi test whether earli administr cqcqd result improv clinic outcom predict msapsap patient

D010195;D004365

T121;T123;T047;T046

36,348,364

registr base assess femor torsion rotat osteotomi base contralater anatomi comput assist techniqu surgic treatment femor deform becom increas import state art deform assess contralater side use templat correct common repres normal anatomi contribut iter closest point icp algorithm use registr howev anatom section femur idiosyncrat featur allow consist deform assess icp algorithm unknown furthermor side side differ consid error quantif aim studi analyz influenc valu differ section femur assess femor deform base contralater anatomi

D014057;D001847

T060;T047