Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
|---|---|---|---|---|---|---|---|
cilium assembly cilium movement flagellated sperm motility protein polyglycylation | axoneme; cilium; microtubule; microtubule cytoskeleton; sperm flagellum | ATP binding metal ion binding protein-glycine ligase activity protein-glycine ligase activity, initiating | Mus musculus | ATP-binding Cell projection Cilium Cytoplasm Cytoskeleton Flagellum Ligase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MSCPPTPNPP | MSCPPTPNPPFRPPSHTRVLRTPPLPPWVCLNSKSLSTGVGGQKNQLREASMENGERKKLSSTLSDGDHKEENKLKQGIPQDLSSSPKLDRYKIARQLTEKAIKERKIFSIYGHYPVIRATLRRKGWVEKKFNFFPKALQNLGSEDKSAETKENQEIALERFDDIHDVMSRLVKNEIPYLLWTIKRDVVDYHSLTCDQMLNHYGKTASFTTKIGLCLNMRSLPWYVQANPNTFFPRCYGLCTESEKQEFLDDFRRTVAASILKWVVLHQNYCSKVKGKSKKEEAKNSDPSPKKDPENPDLKLPSLSGQVVDTACKVCQAY... | cilium assembly cilium movement flagellated sperm motility protein polyglycylation axoneme; cilium; microtubule; microtubule cytoskeleton; sperm flagellum ATP binding metal ion binding protein-glycine ligase activity protein-glycine ligase activity, initiating Mus musculus ATP-binding Cell projection Cilium Cytoplasm C... |
protein polyglycylation | axoneme; cilium; microtubule; microtubule cytoskeleton | ATP binding metal ion binding protein-glycine ligase activity protein-glycine ligase activity, elongating | Mus musculus | Alternative splicing ATP-binding Cell projection Cilium Cytoplasm Cytoskeleton Ligase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MALHPQAGRP | MALHPQAGRPHRDGSEAQAEAAAQDLGRLPSPSKVGAAVCRIQGLGHRAARRPRRGIGTTSASRVPRPGALMPATRNRPRFIHCRGQPPRTRVSSKRSKRSRIHPCHTEVPGWTHEKQMGSSVKERLRPELSQLDQDADDLEEEEAARLPVTSPDGLLMEGDKQPSPGQGPFFYIGGTNGASIISNYCESKGWQRTQDSHCEDYKLKWCEIKCRDNYCSFREGQQLLFQLPNNKLLTTKIGLLSALREHARTLSKARMLPSTQTKVLKMEEFFPETYRLDIRDERQAFFALFDETQMWICKPTASNQGKGIFLIRSQEEA... | protein polyglycylation axoneme; cilium; microtubule; microtubule cytoskeleton ATP binding metal ion binding protein-glycine ligase activity protein-glycine ligase activity, elongating Mus musculus Alternative splicing ATP-binding Cell projection Cilium Cytoplasm Cytoskeleton Ligase Magnesium Metal-binding Microtubule ... |
microtubule cytoskeleton organization microtubule severing protein modification process | ciliary basal body; cilium; cytoplasm; microtubule | ATP binding metal ion binding tubulin binding tubulin-glutamic acid ligase activity | Mus musculus | Alternative splicing ATP-binding Cell projection Cilium Cytoplasm Cytoskeleton Ligase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MRRSSPEKKP | MRRSSPEKKPEAEWEADAAAAAAATAAATESLPAETEKQQGVDAGAAGDPERLELEEQPKDVGRIPTPTRRHAPEEGEARVVRRLPPALPLAQPRPAARALSQLVKARGRSRSRVYRRSAGSMRPVTVDSSKARTSLDALKISLRQLRWKEFPFGRRLPCDIYWHGVSFRDSDILSGQVNKFPGMTEMVRKVTLSRALRIMQNLFPEEYNFYPRSWILPEEFQLFVSQVQTVKEGDPSWKPTFIVKPDSGCQGDGIYLIKDPCDGRLTGTLHNRPAVVQEYIRKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFC... | microtubule cytoskeleton organization microtubule severing protein modification process ciliary basal body; cilium; cytoplasm; microtubule ATP binding metal ion binding tubulin binding tubulin-glutamic acid ligase activity Mus musculus Alternative splicing ATP-binding Cell projection Cilium Cytoplasm Cytoskeleton Ligas... |
ERK1 and ERK2 cascade G1/S transition of mitotic cell cycle negative regulation of activated T cell proliferation negative regulation of cytokine production negative regulation of ERK1 and ERK2 cascade negative regulation of G1/S transition of mitotic cell cycle negative regulation of phosphatidylinositol 3-kinase/prot... | cell surface; external side of plasma membrane | signaling receptor binding | Mus musculus | Alternative splicing Coiled coil Disulfide bond Glycoprotein Immunoglobulin domain Membrane Reference proteome Signal Transmembrane Transmembrane helix | MEPTTSLRSC | MEPTTSLRSCPIASLLFFLVLSLFVLVSAQFTVIGPAEPILAMVGENTTLHCHLSPERNAEEMEVRWFRWRFFPAVLVYRGHQERPEEQMVAYRGRTTFMRTDISKGRVALIIHNVTAYDNGIYCCYFQEGRSYDQATMKLMVASLGSEPLIKMKTLEDGSILLECTSEGWYPEPRAVWRDPYDEVVPALEEEYTADREGLFTVTMTIIIRDCSVRNMTCSVNNTLLSQEVESVILIPESFVPSLPLWMVAVAVTLPVVMLILLTSGSICLVKKHRRKKSILSAEKEAEYEEKEAARQLQEELRWRRTLLHAADVVLDPD... | ERK1 and ERK2 cascade G1/S transition of mitotic cell cycle negative regulation of activated T cell proliferation negative regulation of cytokine production negative regulation of ERK1 and ERK2 cascade negative regulation of G1/S transition of mitotic cell cycle negative regulation of phosphatidylinositol 3-kinase/prot... |
hydrogen peroxide catabolic process response to oxidative stress | extracellular region | catalase activity heme binding metal ion binding | Pyricularia oryzae | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Reference proteome Secreted Signal | MHASLSSWLL | MHASLSSWLLAASLLTQPISVSGQGCPFAKRDGTVDSSLPQKRADAPETTTFGRCAVKSNQAGGGTRSHDWWPCQLRLDVLRQFQPSQNPLGGDFDYAEAFQSLDYEAVKKDIAALMTESQDWWPADFGNYGGLFVRMAWHSAGTYRAMDGRGGGGMGQQRFAPLNSWPDNQNLDKARRLIWPIKQKYGNKISWADLMLLTGNVALENMGFKTLGFGGGRADTWQSDEAVYWGAETTFVPQGNDVRYNNSVDINARADKLEKPLAATHMGLIYVNPEGPNGTPDPAASAKDIREAFGRMGMNDTETVALIAGGHAFGKTH... | hydrogen peroxide catabolic process response to oxidative stress extracellular region catalase activity heme binding metal ion binding Pyricularia oryzae 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Reference proteome Secreted S... |
negative regulation of filamentous growth negative regulation of transcription by RNA polymerase II nuclear-transcribed mRNA catabolic process, non-stop decay phosphorylation positive regulation of developmental process positive regulation of transcription from RNA polymerase II promoter by galactose protein destabiliz... | CKM complex; mediator complex | ATP binding cyclin-dependent protein serine/threonine kinase activity metal ion binding protein serine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity | Pyricularia oryzae | Activator ATP-binding Kinase Magnesium Metal-binding Nucleotide-binding Nucleus Reference proteome Repressor Serine/threonine-protein kinase Transcription Transcription regulation Transferase | MSHSNPPTGA | MSHSNPPTGASGGPGSASASAAPARGYYSLKRSIQTAFNDPLDRGLGPPAYQSKVRVMDKYQVIGFISSGTYGRVYKARGRQGQPGEFAIKKFKPDKEGEQITYTGISQSAIREMALCSELRHPNVIRLVETILEDKAIFMVFEYAEHDLLQIIHHHTQQPKHPIPPQTIKSIMFQLLNGCQYLHTNWVLHRDLKPANIMVTSSGEVKVGDLGLARIFWKPVRTLMQGDKVVVTIWYRAPELLMGSHHYTPAVDMWAVGCIFAELLSLRPIFKGEEAKMDNTKKGGSRDMPFQRHQMQKIVDIMGMPTKERWPLLTSMPD... | negative regulation of filamentous growth negative regulation of transcription by RNA polymerase II nuclear-transcribed mRNA catabolic process, non-stop decay phosphorylation positive regulation of developmental process positive regulation of transcription from RNA polymerase II promoter by galactose protein destabiliz... |
hydrogen peroxide catabolic process response to oxidative stress | cytoplasm | catalase activity heme binding metal ion binding | Pyricularia oryzae | Cytoplasm Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Reference proteome | MGECPLRTAN | MGECPLRTANVAGGGTRNRDWWPNTLKLNILRQHTEATNPYDPNFDYAEAFKSLDYEGLKKDLRALMTDSQEYWPADFGHYGGLFVRMAWHSAGTYRVMDGRGGGGQGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGNKISWADLMLLTGNVALEDMGFKTFGFAGGRPDTWEADESTYWGGETTWLGNEVRYSSGNEGHKESGVIDGSESKKGHKDIHTRDLEKPVSAAHMGLIYVNPEGPDGIPDPVAAARDIRTTFSRMAMNDEETVALIAGGHTVGKTHGAAPSDNVGPEPEAAPIENQGLGWSNKHGSGKGPD... | hydrogen peroxide catabolic process response to oxidative stress cytoplasm catalase activity heme binding metal ion binding Pyricularia oryzae Cytoplasm Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Reference proteome MGECPLRTAN MGECPLRTANVAGGGTRNRDWWPNTLKLNILRQHTEATNPYDPNFDYAEAFKSLDYEGLKKDLRALM... |
cell budding cellular response to oxidative stress invasive growth in response to glucose limitation Mo-molybdopterin cofactor biosynthetic process protein urmylation regulation of pseudohyphal growth tRNA wobble position uridine thiolation | cytosol | AMPylase activity ATP binding identical protein binding metal ion binding molybdopterin-synthase adenylyltransferase activity molybdopterin-synthase sulfurtransferase activity thiosulfate sulfurtransferase activity URM1 activating enzyme activity | Pyricularia oryzae | ATP-binding Cytoplasm Metal-binding Molybdenum cofactor biosynthesis Multifunctional enzyme Nucleotide-binding Reference proteome Transferase tRNA processing Zinc | MEEADKRAEE | MEEADKRAEELRAQIAECEATLQSLKEQLAAAEAAKTPPYSDSTETDRGSSSSTWKWPLAEAEYERYGRQLILPSVGIQGQLRLKAASVLIVGAGGLGCPASAYFAGAGVGTIGLVDGDTVEASNLHRQVAHGTSRVGMLKVDSAISYLRELNPLVKYNAHQSHLTPENAESIVSGYDLVLDCTDHPTSRYLISDVCVLLRKPLVSASALRTDGQLIVLNTPAAPQADLSGGPCYRCVFPKPPPPDAVTSCGEGGILGPVVGVMGVLQALEGIRLLAAGRHLSPSPEQQQTAISPSLLLFSAPPDGSPAGFRSVRMRGRR... | cell budding cellular response to oxidative stress invasive growth in response to glucose limitation Mo-molybdopterin cofactor biosynthetic process protein urmylation regulation of pseudohyphal growth tRNA wobble position uridine thiolation cytosol AMPylase activity ATP binding identical protein binding metal ion bindi... |
fatty acid beta-oxidation | fatty acid beta-oxidation multienzyme complex | 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding | Aeromonas salmonicida | Fatty acid metabolism Isomerase Lipid degradation Lipid metabolism Lyase Multifunctional enzyme NAD Oxidoreductase | MIYQGETLSV | MIYQGETLSVSYLENGIAELRFDAPGSVNKLDRATLLSLSEAIAALQQQADLKGLILTSGKDAFIVGADITEFLELFDLPQEDLLGWLKKANDIFSAIEDLPVPTLSAIKGHALGGGCETILSTDFRLADTSAKIGLPETKLGIMPGFGGTVRLPRVIGADNALEWITTGKDYRADDALKVGAIDAVVAPDALHSAAVQMMKDAIAGKLNWQSRRAAKKAPLRLSKLEAMMSFSTAAGMVAAVAGKHYPAPMTAVKTVEAAAGMSRDEALVVEAQGFIKLAKTDVAKALVGIFLNDQHIKALAKKAAKQAAKATRHAAVL... | fatty acid beta-oxidation fatty acid beta-oxidation multienzyme complex 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding Aeromonas salmonicida Fatty acid metabolism Isomerase Lipid degradation Lipid ... |
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane | host cell plasma membrane; membrane; virion membrane | monoatomic ion channel activity proton transmembrane transporter activity | Influenza A virus | Alternative splicing Disulfide bond Glycoprotein Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel Virion | MSLLTEVETP | MSLLTEVETPIRNEWGCRCNDSSDPLVVAANIIGILHLILWILDRLFFKCIYRLFKHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVNIELE | protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane host cell plasma membrane; membrane; virion membrane monoatomic ion channel activity proton transmembrane transporter activity Influenza A virus Alternative splicing Disulfide bond Glycoprotein Hos... |
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane | host cell plasma membrane; membrane; virion membrane | monoatomic ion channel activity proton transmembrane transporter activity | Influenza A virus | Alternative splicing Disulfide bond Glycoprotein Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel Virion | MSLLTEVETP | MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRLFKHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVNIELE | protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane host cell plasma membrane; membrane; virion membrane monoatomic ion channel activity proton transmembrane transporter activity Influenza A virus Alternative splicing Disulfide bond Glycoprotein Hos... |
cellular response to type II interferon defense response to Gram-positive bacterium defense response to protozoan negative regulation of interferon-alpha production negative regulation of protein import into nucleus negative regulation of protein phosphorylation negative regulation of protein ubiquitination negative re... | cytoplasmic vesicle; Golgi membrane; nucleus; perinuclear region of cytoplasm | GTP binding GTPase activity ubiquitin-protein transferase inhibitor activity | Mus musculus | Alternative splicing Coiled coil Cytoplasm Golgi apparatus GTP-binding Hydrolase Immunity Innate immunity Membrane Nucleotide-binding Nucleus Reference proteome | MTQPQMAPIC | MTQPQMAPICLVENHNEQLSVNQEAIEILDKISQPVVVVAIVGWSHTGKSYLMNCLAGQNHVSGTLPTSQRFPSGLHRAVSDQGHLDVVHAPPHQARALVLLDTEGLGDVEKGDPKNDLWIFALSVLLSSTFVYNSMNTINHQALEQLHYVTELTELIRAKSSPNPHGIKNSTEFVSFFPDFVWTVRDFMLELKLNGEDITSDEYLENALKLIPGNNPRIQASNSARECIRRFFPNRKCFVFEWPTHDIELIKQLETISEDQLDPTFKESAMAFASYIFTYAKIKTLREGIKVTGNGLGTLVTTYVDAINSGAVPCLDDA... | cellular response to type II interferon defense response to Gram-positive bacterium defense response to protozoan negative regulation of interferon-alpha production negative regulation of protein import into nucleus negative regulation of protein phosphorylation negative regulation of protein ubiquitination negative re... |
unsaturated fatty acid biosynthetic process | endoplasmic reticulum membrane; mitochondrion | acyl-CoA delta5-desaturase activity | Papio anubis | Acetylation Alternative splicing Electron transport Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism Membrane Mitochondrion Oxidoreductase Reference proteome Transmembrane Transmembrane helix Transport | MAPDPVAAKT | MAPDPVAAKTPVQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYDISEFTRRHPGGSRVISHYAGQDATDPFVAFHSNKGLVKKYMNSLLIGELSPEQPSFEPTKNKELTDEFRELRATVEQMGLMKANHVFFLLYLLHILLLDGAAWLTLWIFGTSFLPFLLCAVLLTAAQIQAGWLQHDLGHLSVFSTSKWNHLVHHFVIGHLKGVPASWWNHMHFQHHAKPNCFGKDPDINMHPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPPALVPFFFQWYVFYFVIQRKKWVDLAWMITFYIRLLLTYVPLLGLKAFL... | unsaturated fatty acid biosynthetic process endoplasmic reticulum membrane; mitochondrion acyl-CoA delta5-desaturase activity Papio anubis Acetylation Alternative splicing Electron transport Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism Membrane Mitochondrion Ox... |
arachidonic acid secretion lipid catabolic process phospholipid metabolic process | extracellular region | calcium ion binding phospholipase A2 activity phospholipase A2 inhibitor activity toxin activity | Vipera berus nikolskii | Blood coagulation cascade inhibiting toxin Direct protein sequencing Disulfide bond Hemostasis impairing toxin Neurotoxin Phospholipase A2 inhibitor Platelet aggregation inhibiting toxin Presynaptic neurotoxin Secreted Signal Toxin | MRTLWIVAVC | MRTLWIVAVCLIGVEGNLFQFGDMILQKTGKEAVHSYAIYGCYCGWGGQGRAQDATDRCCFAQDCCYGRVNDCNPKTATYTYSFENGDIVCGDNDLCLRAVCECDRAAAICLGENVNTYDKNYEYYSISHCTEESEQC | arachidonic acid secretion lipid catabolic process phospholipid metabolic process extracellular region calcium ion binding phospholipase A2 activity phospholipase A2 inhibitor activity toxin activity Vipera berus nikolskii Blood coagulation cascade inhibiting toxin Direct protein sequencing Disulfide bond Hemostasis i... |
protein phosphorylation | extracellular region; Golgi apparatus; Golgi membrane | ATP binding metal ion binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Drosophila melanogaster | Alternative splicing ATP-binding Disulfide bond Glycoprotein Golgi apparatus Kinase Manganese Membrane Metal-binding Nucleotide-binding Reference proteome Secreted Serine/threonine-protein kinase Signal-anchor Transferase Transmembrane Transmembrane helix | MAVLRTMKLK | MAVLRTMKLKERLVISLGATLVLLTLLLIVDVQMDFGVANRHLLQQQHQKIRLGNDYDGGTGGGGMLHEFKRKFLQKSNASGSKEASTQAGASQSGGATSGQDAAAGASGGAAGPGTSRSTSTRKPTPHDRYADLQKHLLSDEYSHVIVDNAPDVSRDNPTLAEMLHRKASANASNLERFQLRITKKELYGEQDTLVDAVLRDMIKLPIQHVVQKEGGTQLKLIIEYPNDIKALMKPMRFPREQQTLPNHFYFTDYERHNAEIAAFHLDRILGFRRAMPVAGRTLNITTEIYQLAEENLLKTFFVSPSLNLCFHGKCSYY... | protein phosphorylation extracellular region; Golgi apparatus; Golgi membrane ATP binding metal ion binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity Drosophila melanogaster Alternative splicing ATP-binding Disulfide bond Glycoprotein Golgi apparatus Kinase Manganes... |
ectoine biosynthetic process phosphorylation | cytoplasm | aspartate kinase activity ATP binding | Stutzerimonas stutzeri | Allosteric enzyme ATP-binding Cytoplasm Kinase Nucleotide-binding Reference proteome Transferase | MHTVEKIGGT | MHTVEKIGGTSMSRFEEVLDNIFIGRREGAALYQRIFVVSAYSGMTNLLLEHKKTGEPGVYQRFADAQSEGAWREALEGVRQRMLAKNAELFSSEYELHAANQFINSRIDDASECMHSLQKLCAYGHFQLSEHLMKVREMLASLGEAHSAFNSVLALKQRGVNARLADLTGWQQEAPLPFEEMISSHFAGFDFSRELVVATGYTHCAEGLMNTFDRGYSEITFAQIAAATGAREAIIHKEFHLSSADPNLVGADKVVTIGRTNYDVADQLSNLGMEAIHPRAAKTLRRAGVELRIKNAFEPEHGGTLISQDYKSEKPCVE... | ectoine biosynthetic process phosphorylation cytoplasm aspartate kinase activity ATP binding Stutzerimonas stutzeri Allosteric enzyme ATP-binding Cytoplasm Kinase Nucleotide-binding Reference proteome Transferase MHTVEKIGGT MHTVEKIGGTSMSRFEEVLDNIFIGRREGAALYQRIFVVSAYSGMTNLLLEHKKTGEPGVYQRFADAQSEGAWREALEGVRQRMLAKNAELFSSE... |
fatty acid beta-oxidation | fatty acid beta-oxidation multienzyme complex | 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding | Enterobacter sp. | Fatty acid metabolism Isomerase Lipid degradation Lipid metabolism Lyase Multifunctional enzyme NAD Oxidoreductase | MLYKGDTLYV | MLYKGDTLYVDWLEDGIAELVFDAPGSVNKLDTATVASLGHALDVLEKQSDLKGLLLRSEKAAFIVGADITEFLSLFQVPEEQLSQWLHFANSVFNRLEDLPVPTISAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALKIGLIDGIVKAEKLRDGAISILRQAINGDLDWKAKRQRKLEPLKLSKIEATMSFTIAKGMVMQTAGKHYPAPITAVKTIEAAARLGREEALKLENQSFVPLAHTNEARALVGIFLNDQFVKGKAKQLTKNVEMPKQAAVLG... | fatty acid beta-oxidation fatty acid beta-oxidation multienzyme complex 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding Enterobacter sp. Fatty acid metabolism Isomerase Lipid degradation Lipid metab... |
fatty acid metabolic process | membrane | acetate-CoA ligase activity ATP binding butyrate-CoA ligase activity medium-chain fatty acid-CoA ligase activity propionate-CoA ligase activity | Metallosphaera sedula | ATP-binding Fatty acid metabolism Ligase Lipid metabolism Magnesium Membrane Nucleotide-binding Reference proteome Transmembrane Transmembrane helix | MVTVQDFFRK | MVTVQDFFRKFIEFQNSPNEKSLQEIVKLVGQLDLRRFNWVRDVFEDIHVKERGSKTALIWRDINTGEEAKLSYHELSLMSNRVLSTLRKHGLKKGDVVYLMTKVHPMHWAVFLAVIKGGFVMVPSATNLTVAEMKYRFSDLKPSAIISDSLRASVMEEALGSLKVEKFLIDGKRETWNSLEDESSNAEPEDTRGEDVIINYFTSGTTGMPKRVIHTAVSYPVGSITTASIVGVRESDLHLNLSATGWAKFAWSSFFSPLLVGATVVGINYEGKLDTRRYLGEVENLGVTSFCAPPTAWRQFITLDLDQFRFERLRSVVS... | fatty acid metabolic process membrane acetate-CoA ligase activity ATP binding butyrate-CoA ligase activity medium-chain fatty acid-CoA ligase activity propionate-CoA ligase activity Metallosphaera sedula ATP-binding Fatty acid metabolism Ligase Lipid metabolism Magnesium Membrane Nucleotide-binding Reference proteome T... |
defense response to bacterium defense response to fungus induction of programmed cell death killing of cells of another organism | extracellular space | actin binding aspartic-type endopeptidase inhibitor activity mannose binding | Ginkgo biloba | 3D-structure Actin-binding Antibiotic Antimicrobial Apoptosis Direct protein sequencing Disulfide bond Fungicide Lectin Mannose-binding Plant defense Secreted Signal | MKTMRMNSAF | MKTMRMNSAFILAFALAAAMLILTEAANTAFVSSACNTQKIPSGSPFNRNLRAMLADLRQNTAFSGYDYKTSRAGSGGAPTAYGRATCKQSISQSDCTACLSNLVNRIFSICNNAIGARVQLVDCFIQYEQRSF | defense response to bacterium defense response to fungus induction of programmed cell death killing of cells of another organism extracellular space actin binding aspartic-type endopeptidase inhibitor activity mannose binding Ginkgo biloba 3D-structure Actin-binding Antibiotic Antimicrobial Apoptosis Direct protein se... |
negative regulation of amyloid precursor protein biosynthetic process | endosome membrane; extracellular space; Golgi apparatus; Golgi membrane; Golgi-associated vesicle membrane; organelle membrane; plasma membrane | amyloid-beta binding ATP binding | Pan troglodytes | Cell membrane Disulfide bond Endosome Glycoprotein Golgi apparatus Membrane Reference proteome Secreted Signal-anchor Transmembrane Transmembrane helix | MVKVTFNSAL | MVKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDDVVPVGQRRAWCWCMCFGLAFMLAGVILGGAYLYKYFALQPDDVYYCGIKYIKDDVILNEPSADAPAALYQTIEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHMVITDRIENIDHLGFFIYRLCHDKETYKLQRRETIKGIQKREASNCFAIRHFENKFAVETLICS | negative regulation of amyloid precursor protein biosynthetic process endosome membrane; extracellular space; Golgi apparatus; Golgi membrane; Golgi-associated vesicle membrane; organelle membrane; plasma membrane amyloid-beta binding ATP binding Pan troglodytes Cell membrane Disulfide bond Endosome Glycoprotein Golgi ... |
fructose 1,6-bisphosphate metabolic process glycolytic process protein homotetramerization | cytosol; I band; M band | fructose-bisphosphate aldolase activity | Pan troglodytes | Acetylation Cytoplasm Glycolysis Hydroxylation Isopeptide bond Lyase Phosphoprotein Reference proteome Schiff base Ubl conjugation | MPYQYPALTP | MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIVGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIAEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKEN... | fructose 1,6-bisphosphate metabolic process glycolytic process protein homotetramerization cytosol; I band; M band fructose-bisphosphate aldolase activity Pan troglodytes Acetylation Cytoplasm Glycolysis Hydroxylation Isopeptide bond Lyase Phosphoprotein Reference proteome Schiff base Ubl conjugation MPYQYPALTP MPYQYPA... |
actin filament organization antibacterial humoral response cellular response to iron ion ERK1 and ERK2 cascade intracellular iron ion homeostasis iron ion transport osteoclast differentiation positive regulation of bone resorption positive regulation of cell motility positive regulation of DNA-templated transcription p... | apical plasma membrane; basal plasma membrane; cell surface; clathrin-coated pit; early endosome; endocytic vesicle; extracellular space; HFE-transferrin receptor complex; late endosome; perinuclear region of cytoplasm; plasma membrane; recycling endosome | ferric iron binding ferrous iron binding iron chaperone activity transferrin receptor binding | Pan troglodytes | Disulfide bond Glycoprotein Ion transport Iron Iron transport Metal-binding Methylation Phosphoprotein Reference proteome Repeat Secreted Signal Transport | MRLAVGALLV | MRLAVGALLVCAVLGLCLAVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANFFSGSCAPCADGTDFPQLCQLCPGCGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHG... | actin filament organization antibacterial humoral response cellular response to iron ion ERK1 and ERK2 cascade intracellular iron ion homeostasis iron ion transport osteoclast differentiation positive regulation of bone resorption positive regulation of cell motility positive regulation of DNA-templated transcription p... |
adult locomotory behavior cellular response to calcium ion centrosome cycle cerebellar cortex morphogenesis cerebral cortex development dentate gyrus development forebrain morphogenesis gene expression glial cell differentiation homeostasis of number of cells within a tissue intracellular protein transport locomotory e... | axonemal microtubule; condensed chromosome; cytoplasm; cytoplasmic ribonucleoprotein granule; cytosol; microtubule; neuromuscular junction; plasma membrane; recycling endosome | GTP binding hydrolase activity identical protein binding metal ion binding protein heterodimerization activity protein-containing complex binding structural constituent of cytoskeleton | Pan troglodytes | Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Isopeptide bond Magnesium Metal-binding Methylation Microtubule Nitration Nucleotide-binding Phosphoprotein Reference proteome | MRECISIHVG | MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYR... | adult locomotory behavior cellular response to calcium ion centrosome cycle cerebellar cortex morphogenesis cerebral cortex development dentate gyrus development forebrain morphogenesis gene expression glial cell differentiation homeostasis of number of cells within a tissue intracellular protein transport locomotory e... |
alternative mRNA splicing, via spliceosome androgen receptor signaling pathway epithelial to mesenchymal transition intracellular estrogen receptor signaling pathway intrinsic apoptotic signaling pathway by p53 class mediator miRNA transcription myoblast differentiation negative regulation of transcription by RNA polym... | cytoplasm; nuclear speck; nucleolus; nucleus; ribonucleoprotein complex; spliceosomal complex | ATP binding ATP hydrolysis activity mRNA 3'-UTR binding nuclear androgen receptor binding promoter-specific chromatin binding ribonucleoprotein complex binding RNA helicase activity | Pan troglodytes | Acetylation ATP-binding Biological rhythms Cytoplasm Helicase Hydrolase Isopeptide bond Methylation mRNA processing mRNA splicing Nucleotide-binding Nucleus Phosphoprotein Reference proteome RNA-binding Spliceosome Transcription Transcription regulation Ubl conjugation | MSGYSSDRDR | MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVENCIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVC... | alternative mRNA splicing, via spliceosome androgen receptor signaling pathway epithelial to mesenchymal transition intracellular estrogen receptor signaling pathway intrinsic apoptotic signaling pathway by p53 class mediator miRNA transcription myoblast differentiation negative regulation of transcription by RNA polym... |
ATP metabolic process cardiac muscle contraction cell adhesion innate immune response intracellular calcium ion homeostasis intracellular potassium ion homeostasis intracellular sodium ion homeostasis membrane repolarization positive regulation of potassium ion import across plasma membrane positive regulation of sodiu... | apical plasma membrane; basolateral plasma membrane; intercalated disc; lateral plasma membrane; organelle membrane; sodium:potassium-exchanging ATPase complex; sperm flagellum; T-tubule | ATPase activator activity ATPase binding P-type sodium:potassium-exchanging transporter activity protein kinase binding protein-macromolecule adaptor activity | Pan troglodytes | Cell adhesion Cell membrane Disulfide bond Glutathionylation Glycoprotein Immunity Innate immunity Ion transport Membrane Phosphoprotein Potassium Potassium transport Reference proteome Signal-anchor Sodium Sodium transport Sodium/potassium transport Transmembrane Transmembrane helix Transport | MARGKAKEEG | MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEAYVLNIVRFLEKYKDSAQRDDMIFEDCGDVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGLNDETYGYKEGKPCIIIKLNRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGKRDEDKDKIGNVEYFGLGNSPGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYSEKDRFQGRFDVKIEVKS | ATP metabolic process cardiac muscle contraction cell adhesion innate immune response intracellular calcium ion homeostasis intracellular potassium ion homeostasis intracellular sodium ion homeostasis membrane repolarization positive regulation of potassium ion import across plasma membrane positive regulation of sodiu... |
cellular response to heat protein folding protein stabilization response to antibiotic response to cold response to heat | cytoplasm; cytosol; melanosome; myelin sheath; neuronal cell body; nucleus; perinuclear region of cytoplasm; plasma membrane; protein-containing complex | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone disordered domain specific binding unfolded protein binding | Pan troglodytes | Acetylation ATP-binding Cell membrane Chaperone Cytoplasm Membrane Nucleotide-binding Nucleus Phosphoprotein Reference proteome S-nitrosylation Stress response Ubl conjugation | MPEETQTQDQ | MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVIPHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTND... | cellular response to heat protein folding protein stabilization response to antibiotic response to cold response to heat cytoplasm; cytosol; melanosome; myelin sheath; neuronal cell body; nucleus; perinuclear region of cytoplasm; plasma membrane; protein-containing complex ATP binding ATP hydrolysis activity ATP-depend... |
cellular response to interleukin-1 membrane protein ectodomain proteolysis mRNA processing negative regulation of mRNA splicing, via spliceosome positive regulation of mRNA splicing, via spliceosome positive regulation of transcription by RNA polymerase II protein homooligomerization regulation of alternative mRNA spli... | catalytic step 2 spliceosome; euchromatin; extracellular exosome; nucleus; spliceosomal complex; supraspliceosomal complex | chromatin binding mRNA binding RNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Pan troglodytes | Acetylation Activator Glycoprotein Isopeptide bond Methylation mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repressor Ribonucleoprotein RNA-binding Spliceosome Transcription Tumor suppressor Ubl conjugation | MVEADRPGKL | MVEADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVEQATKPSFESGRRGPPPPPRSRGPPRGLRGGRGGSGGTRGPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGGPPPKRSAPSGPVRSSSGMGGRAPVSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYSDRDGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPPTRGPPPSYGGSSRYDDYSSSRDGY... | cellular response to interleukin-1 membrane protein ectodomain proteolysis mRNA processing negative regulation of mRNA splicing, via spliceosome positive regulation of mRNA splicing, via spliceosome positive regulation of transcription by RNA polymerase II protein homooligomerization regulation of alternative mRNA spli... |
cellular response to tumor necrosis factor ceramide biosynthetic process ceramide catabolic process fatty acid metabolic process keratinocyte differentiation regulation of programmed necrotic cell death regulation of steroid biosynthetic process sphingosine biosynthetic process | extracellular space; lysosome | ceramidase activity fatty acid amide hydrolase activity N-acylsphingosine amidohydrolase activity | Pan troglodytes | Disulfide bond Glycoprotein Hydrolase Lipid metabolism Lysosome Reference proteome Secreted Signal Sphingolipid metabolism Zymogen | MPGRSRVALV | MPGRSRVALVLLAAAVSCAVAQHAPPWTEDCRKSTYPPSGPTYRGPVPWYTINLDLPPYKRWHELMLDKAPMLKVIVNSLKNMINTFVPSGKIVQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLSLNERFSINGGYLGILEWILGKKDAMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDVYELDAKQGRWYVVQTN... | cellular response to tumor necrosis factor ceramide biosynthetic process ceramide catabolic process fatty acid metabolic process keratinocyte differentiation regulation of programmed necrotic cell death regulation of steroid biosynthetic process sphingosine biosynthetic process extracellular space; lysosome ceramidase ... |
cell migration cell migration involved in gastrulation cell proliferation involved in kidney development coronary vasculature development mesonephric duct morphogenesis negative regulation of smoothened signaling pathway positive regulation of canonical Wnt signaling pathway positive regulation of endocytosis positive ... | cell surface; collagen-containing extracellular matrix; lysosomal lumen; plasma membrane; side of membrane | peptidyl-dipeptidase inhibitor activity | Pan troglodytes | Cell membrane Disulfide bond Glycoprotein GPI-anchor Heparan sulfate Lipoprotein Membrane Phosphoprotein Protease inhibitor Proteoglycan Pyrrolidone carboxylic acid Reference proteome Signal | MAGTVRTACL | MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASKELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVL... | cell migration cell migration involved in gastrulation cell proliferation involved in kidney development coronary vasculature development mesonephric duct morphogenesis negative regulation of smoothened signaling pathway positive regulation of canonical Wnt signaling pathway positive regulation of endocytosis positive ... |
intracellular signal transduction phosphorylation | cytoplasm; nucleus; plasma membrane | ATP binding calcium ion binding calcium-dependent protein serine/threonine kinase activity calmodulin binding calmodulin-dependent protein kinase activity protein serine kinase activity | Solanum tuberosum | ATP-binding Calcium Cell membrane Kinase Lipoprotein Membrane Metal-binding Myristate Nucleotide-binding Palmitate Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase | MGNACRGSFG | MGNACRGSFGGKTFQGYPQPQDHSESNSNPKHNSDSPKPKKEQQPLVTMNRTSTNQSYYVLGHKTPNIRDLYTLGRKLGQGQFGTTYLCTELSSGIDYACKSIAKRKLISKEDVEDVRREIQIMHHLAGHKNIVSIKGAYEDPLYVHIVMELCGGGELFDRIIQRGHYTERKAADLTKIIVGVVEACHSLGVMHRDLKPENFLLVNKDDDFSLKAIDFGLSVFFKPGQIFTDVVGSPYYVAPEVLLKHYGPEADVWTAGVILYILLSGVPPFWAETQQGIFDAVLKGHIDFDSDPWPLLSESAKDLIRKMLCMRPSERLT... | intracellular signal transduction phosphorylation cytoplasm; nucleus; plasma membrane ATP binding calcium ion binding calcium-dependent protein serine/threonine kinase activity calmodulin binding calmodulin-dependent protein kinase activity protein serine kinase activity Solanum tuberosum ATP-binding Calcium Cell membr... |
angiogenesis cell adhesion endothelial cell migration melanocyte apoptotic process melanocyte proliferation negative regulation of cell proliferation involved in contact inhibition negative regulation of extracellular matrix disassembly positive regulation of execution phase of apoptosis proteolysis proteolysis involve... | anchoring junction; apical part of cell; basal part of cell; cell surface; extracellular space; lamellipodium membrane; peptidase complex; plasma membrane; ruffle membrane | dipeptidyl-peptidase activity integrin binding protease binding protein homodimerization activity serine-type endopeptidase activity | Bos taurus | Angiogenesis Apoptosis Cell adhesion Cell junction Cell membrane Cell projection Cleavage on pair of basic residues Coiled coil Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Membrane Protease Reference proteome Secreted Serine protease Signal-anchor Transmembrane Transmembrane helix | MKTWLKIVFG | MKTWLKIVFGVATSAVLALLVMCIVLRPSRVHNSEESTTRALTLKDILNGTFSYKTFFPNWISGQEYLHQSTDNNVVFYNIETGESYTILSNTTMKSVNASNYGLSPDRQFAYLESDYSKLWRYSYTATYHIYDLTNGEFIRRNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPEDPPFQITYNGKENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTEIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDATYPEHIGPREVPVPAMIASSDYYFSWLTWVTDDRICLQWLKRIQNVSVLST... | angiogenesis cell adhesion endothelial cell migration melanocyte apoptotic process melanocyte proliferation negative regulation of cell proliferation involved in contact inhibition negative regulation of extracellular matrix disassembly positive regulation of execution phase of apoptosis proteolysis proteolysis involve... |
actin cytoskeleton organization muscle cell development peroxisome proliferator activated receptor signaling pathway protein transport retinoic acid receptor signaling pathway | anchoring junction; cell junction; cell projection; cortical actin cytoskeleton; cytoplasm; nucleus; perinuclear region of cytoplasm; plasma membrane; ribonucleoprotein complex; stress fiber; Z disc | actin filament binding calcium ion binding nuclear receptor coactivator activity | Bos taurus | Acetylation Actin-binding Calcium Cell junction Cytoplasm Cytoskeleton Metal-binding Nucleus Phosphoprotein Protein transport Reference proteome Repeat Transport | MVDYHAANQS | MVDYHAANQSYQYGPSSGSNGAGGGGTMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYERLASDLLEWIRRTIPWLEDRV... | actin cytoskeleton organization muscle cell development peroxisome proliferator activated receptor signaling pathway protein transport retinoic acid receptor signaling pathway anchoring junction; cell junction; cell projection; cortical actin cytoskeleton; cytoplasm; nucleus; perinuclear region of cytoplasm; plasma mem... |
negative regulation of apoptotic process negative regulation of extrinsic apoptotic signaling pathway neuron migration positive regulation of JNK cascade positive regulation of proteasomal ubiquitin-dependent protein catabolic process protein autoubiquitination protein ubiquitination regulation of CD4-positive, alpha-b... | cytosol; Golgi apparatus; lamellipodium; perinuclear region of cytoplasm | MAP-kinase scaffold activity metal ion binding ubiquitin protein ligase activity | Bos taurus | Cell projection Cytoplasm Golgi apparatus Metal-binding Phosphoprotein Reference proteome Repeat SH3 domain Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MDESALLDLL | MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELRCPECRTLVGSGVEQLPSNILLVRLLDGIKQRPWKPGPVGGSGTNGTSALRAQSSAVVTCSPKDGPSSQGGPQPRAQAWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIVLRRQVDENWYHGEVGGVHGFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNSAAKQLIEWDQPPGPGVAAGEGALATTPSSTTTKQPDGKKNTKKRHSFTSLSMASKASQAAQQ... | negative regulation of apoptotic process negative regulation of extrinsic apoptotic signaling pathway neuron migration positive regulation of JNK cascade positive regulation of proteasomal ubiquitin-dependent protein catabolic process protein autoubiquitination protein ubiquitination regulation of CD4-positive, alpha-b... |
cellular response to glucose stimulus cellular response to insulin stimulus import across plasma membrane inorganic cation transmembrane transport intracellular zinc ion homeostasis iron import into cell iron ion transmembrane transport manganese ion homeostasis manganese ion transmembrane transport negative regulation... | apical plasma membrane; basolateral plasma membrane; early endosome membrane; late endosome membrane; lysosomal membrane; plasma membrane | cadmium ion transmembrane transporter activity iron ion transmembrane transporter activity manganese ion transmembrane transporter activity monoatomic anion:monoatomic cation symporter activity monoatomic cation:bicarbonate symporter activity zinc ion transmembrane transporter activity | Bos taurus | Cell membrane Endosome Glycoprotein Ion transport Lysosome Membrane Reference proteome Signal Transmembrane Transmembrane helix Transport Ubl conjugation Zinc Zinc transport | MELLRPALPS | MELLRPALPSYFLLTLLSIWTAASEARAVSTGMPTISAASFLQNLMHRYGEGDSLTLQQLKALLNHLDVGVGRGNISQPVQGPRNLSTCFSSGELFAAHNLSHQSQIGEREFQEFCPTILQQLDSRACSSENQENEENEQTEEGRPSSVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPMEDYYVSKSAVVFGGFYLFFFTEKILKMLLKQKNEHHHGHSHYTSETLPSQKDQEEGVTEKLQNGDLDHMIPQHCSGELDGKTPVVDEKVIVGSLSVQDLQASQSAC... | cellular response to glucose stimulus cellular response to insulin stimulus import across plasma membrane inorganic cation transmembrane transport intracellular zinc ion homeostasis iron import into cell iron ion transmembrane transport manganese ion homeostasis manganese ion transmembrane transport negative regulation... |
aldosterone metabolic process artery smooth muscle contraction cellular response to acidic pH cellular response to aldosterone epithelial fluid transport erythrocyte homeostasis gene expression intracellular sodium ion homeostasis leukocyte activation involved in inflammatory response mucus secretion multicellular orga... | apical plasma membrane; cytoplasmic vesicle membrane; external side of plasma membrane; extracellular exosome; sodium channel complex | ligand-gated sodium channel activity WW domain binding | Bos taurus | Cell membrane Cytoplasmic vesicle Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Reference proteome Sensory transduction Sodium Sodium channel Sodium transport Taste Transmembrane Transmembrane helix Transport | MHVKKYLLKG | MHVKKYLLKGLHRLQKGPGYTYKELLVWYCDNTNTHGPKRIICEGPKKKAMWFVLTLLFTSLVCWQWGLFIKTYLNWEVSVSLSIGFKTMDFPAVTICNASPFQYSKVQHLLKDLDELMEAVLGRILGPELSQVNDTRALNLSIWHHTPLVFINEQNPHHPVVLDLFEDNFNGSASNSPAPGRPCSAHRCKVAMRLCSHNGTTCTFRNFSSATQAVTEWYTLQATNIFAQVPNQELVAMGYPAERLILACLFGAEPCNYRNFTPIFHPDYGNCYIFNWGMTEKALPSANPGTEFGLKLILDMGQEDYVPFLTSTAGARLM... | aldosterone metabolic process artery smooth muscle contraction cellular response to acidic pH cellular response to aldosterone epithelial fluid transport erythrocyte homeostasis gene expression intracellular sodium ion homeostasis leukocyte activation involved in inflammatory response mucus secretion multicellular orga... |
apoptotic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of proteolysis nucleotide-binding oligomerization domain containing 2 signaling pathway positive regulation of canonical NF-kappaB signal transduction ... | cytoplasm; nucleus | cysteine-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process metal ion binding ubiquitin-protein transferase activity | Xenopus laevis | Alternative splicing Apoptosis Cytoplasm Developmental protein Metal-binding Nucleus Protease inhibitor Reference proteome Repeat Thiol protease inhibitor Transferase Ubl conjugation pathway Wnt signaling pathway Zinc Zinc-finger | MEPQIVKFVF | MEPQIVKFVFKEEMTCQCPKMSDSACDVDTDQNYFEEEVRLASFANFSSSYPVSAPALARAGFYYTGDGDRVKCFSCMAMVEDWQHGDTAIGKHRKISPNCKFINGFNNFRSDCIQTQAPVMQNSHANGFPNSAEDPGEKSSSEIMADYMLRTGRVVDMSKPKYPRHMAMCSEEARLQTFQNWPGYSPLMPKELANAGLFYTGINDQVKCFCCGGKLMNWEPSDRAWTEHKKHFPECYFVLGRDVGNVTRDASVQGSTYMNSYNARLETFSSWPFPIDKETLAKAGFYRIGDEDATKCFSCGGMLNCWAANDDPWEEHAK... | apoptotic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of proteolysis nucleotide-binding oligomerization domain containing 2 signaling pathway positive regulation of canonical NF-kappaB signal transduction ... |
negative regulation of apoptotic process neuron migration positive regulation of JNK cascade positive regulation of proteasomal ubiquitin-dependent protein catabolic process protein autoubiquitination protein ubiquitination regulation of CD4-positive, alpha-beta T cell differentiation regulation of CD8-positive, alpha-... | Golgi apparatus; lamellipodium; perinuclear region of cytoplasm | MAP-kinase scaffold activity metal ion binding ubiquitin protein ligase activity | Danio rerio | Cell projection Cytoplasm Golgi apparatus Metal-binding Reference proteome Repeat SH3 domain Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MDESALLDLL | MDESALLDLLECPVCLERLDATAKVLPCQHTFCRRCLLGIVGSRGELRCPECRTLVESGVDELPSNILLVRLLDGIKQRPRRTGSVHGTCANGSAVAGVRAQGAGGSQRDPGPTGGQSQRVQAKSTPVRGVPQLPCAKALYNYDGKEPGDLKFSKGDIIILRRQVDENWYHGEMGGVHGFFPTNFVQVIKPLPQPPPQCKALYDFELKDKEADKDCLPFSKDDILTVIRRVDENWAEGMLGDKIGIFPISYVEFNSAARQLIELDKPSEGGGDSSEGPSSSSSGPQANGSQKAPGEKKNSKKRHSFTSLTMSHKPCLAPP... | negative regulation of apoptotic process neuron migration positive regulation of JNK cascade positive regulation of proteasomal ubiquitin-dependent protein catabolic process protein autoubiquitination protein ubiquitination regulation of CD4-positive, alpha-beta T cell differentiation regulation of CD8-positive, alpha-... |
macroautophagy membrane fission multivesicular body assembly protein targeting to membrane protein targeting to vacuole protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ubiquitin-dependent protein catabolic process via the multivesicular ... | endosome membrane; ESCRT I complex; extracellular exosome; late endosome membrane | calcium-dependent protein binding | Homo sapiens | Endosome Membrane Phosphoprotein Protein transport Reference proteome Transport | METLKDKTLQ | METLKDKTLQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPLEISRSNLSDRYQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAEKFLEGEVPLETFLENFSSMRMLSHLRRVRVEKLQEVVRKPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSF... | macroautophagy membrane fission multivesicular body assembly protein targeting to membrane protein targeting to vacuole protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ubiquitin-dependent protein catabolic process via the multivesicular ... |
DNA damage response positive regulation of protein ubiquitination protein autoprocessing protein-DNA covalent cross-linking repair proteolysis response to UV S-adenosylmethionine biosynthetic process translesion synthesis | chromatin; nuclear speck; nucleus | double-stranded DNA binding K63-linked polyubiquitin modification-dependent protein binding metal ion binding metalloendopeptidase activity methionine adenosyltransferase activity polyubiquitin modification-dependent protein binding single-stranded DNA binding ubiquitin binding | Bos taurus | Acetylation Autocatalytic cleavage Chromosome DNA damage DNA repair Hydrolase Isopeptide bond Metal-binding Metalloprotease Nucleus Phosphoprotein Protease Reference proteome Ubl conjugation Zinc Zinc-finger | MDEDLVLALQ | MDEDLVLALQLQEEWNLQVSEREPAQEPLSLVDASWELVDPTPDLQGLFVLFNDRFFWGQLEAVEVKWSVRMTLCAGICSYEGRGGMCSIRLSEPLLKLRPRKDLVETLLHEMIHAYLFVTNNDKDREGHGPEFCKHMHRINRLTGANITVYHTFHDEVDEYRRHWWRCNGPCQNSKPYYGYVKRATNRAPSAHDYWWAEHQKTCGGTYIKIKEPENYSKKGKGKTKLRKQPVSEAENKDKPNRGEKQLLIPFTGKGYVLGETSNFSSGKCITSHAINESQEPLSQDHSANALRPHSKTEVKFEQNGPSKKTSVASPVLS... | DNA damage response positive regulation of protein ubiquitination protein autoprocessing protein-DNA covalent cross-linking repair proteolysis response to UV S-adenosylmethionine biosynthetic process translesion synthesis chromatin; nuclear speck; nucleus double-stranded DNA binding K63-linked polyubiquitin modificatio... |
sodium ion transport | plasma membrane | antiporter activity | Vibrio cholerae serotype O1 | Antiport Cell inner membrane Cell membrane Direct protein sequencing Ion transport Membrane Sodium Sodium transport Transmembrane Transmembrane helix Transport | MTGRIALLSL | MTGRIALLSLTLFSPLSLASTPDGQALDFTHSTIGYAALLIFAIAYTLVMLEEYLQLRKSKPVLLAAGLIWAMIGYVYQQTGSTEVARQALEHNLLEYAELLLFLLVAMTYISAMEERRLFDALKAWMINRGFNFHTLFWITGWLAFFISPIADNLTTALLMCAVVMKVGGENPKFVSLACINIVIAANAGGAFSPFGDITTLMVWQAGHVSFLEFMDLFLPSLANYLVPALVMSLFVPHQTPSSIQEVVELKRGAKRIVVLFLFTILSAIGFHAFFHFPPVIGMMMGLAYLQFFGYFLRKTLARSLAKKTAIAMAKNDE... | sodium ion transport plasma membrane antiporter activity Vibrio cholerae serotype O1 Antiport Cell inner membrane Cell membrane Direct protein sequencing Ion transport Membrane Sodium Sodium transport Transmembrane Transmembrane helix Transport MTGRIALLSL MTGRIALLSLTLFSPLSLASTPDGQALDFTHSTIGYAALLIFAIAYTLVMLEEYLQLRKSKPVL... |
fatty acid beta-oxidation | fatty acid beta-oxidation multienzyme complex | 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding | Vibrio cholerae serotype O1 | Fatty acid metabolism Isomerase Lipid degradation Lipid metabolism Lyase Multifunctional enzyme NAD Oxidoreductase | MIYQAKTLQV | MIYQAKTLQVKQLANGIAELSFCAPASVNKLDLHTLESLDKALDALAADSSVKGLLLSSDKEAFIVGADITEFLGLFAKPEAELDEWLQFANRIFNKLEDLPFPTLSALKGHTLGGGCECVLATDFRIGDATTSIGLPETKLGIMPGFGGTVRLPRLIGADSAMEIITQGKACRAEEALKVGLLDAIVDSDKLIDSAITTLTQAIEEKLDWQKRRQQKTSALTLSKLEAMMSFTMAKGMVAQVAGKHYPAPMTSVVTIEEAARLPRDAALDIERKHFIKLAKSTEAQALVGIFLNDQYIKGLAKQSAKAASQDTQHAAVL... | fatty acid beta-oxidation fatty acid beta-oxidation multienzyme complex 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding Vibrio cholerae serotype O1 Fatty acid metabolism Isomerase Lipid degradation ... |
endoplasmic reticulum membrane organization endoplasmic reticulum unfolded protein response endoplasmic reticulum-plasma membrane tethering intracellular calcium ion homeostasis IRE1-mediated unfolded protein response positive regulation of viral genome replication | endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; plasma membrane | beta-tubulin binding enzyme binding FFAT motif binding protein heterodimerization activity protein homodimerization activity | Sus scrofa | Acetylation Coiled coil Endoplasmic reticulum Isopeptide bond Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Ubl conjugation Unfolded protein response | MAKVEQVLSL | MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPADTSDMEAAWKEAKPEDLMDSKLRCVFELPAENDKPHDVEINKIISTTASKTETPVVSKALSSALDDTEVKKVMEECKRLQSEVQRLREENKQLKEEDGLRMRKPVLSNSPAPAPATPGKEEGLSTRLLALVVLFFIVGVIIGKIAL | endoplasmic reticulum membrane organization endoplasmic reticulum unfolded protein response endoplasmic reticulum-plasma membrane tethering intracellular calcium ion homeostasis IRE1-mediated unfolded protein response positive regulation of viral genome replication endoplasmic reticulum; endoplasmic reticulum membrane;... |
cell division cilium disassembly meiotic spindle organization mitotic centrosome separation mitotic spindle organization phosphorylation positive regulation of meiotic cell cycle process involved in oocyte maturation positive regulation of mitotic cell cycle positive regulation of translation regulation of cytokinesis | basolateral plasma membrane; centriole; centrosome; chromosome passenger complex; ciliary basal body; cytoplasm; kinetochore; mitotic spindle pole; neuron projection; spindle microtubule; spindle midzone; spindle pole; spindle pole centrosome | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Sus scrofa | ATP-binding Cell cycle Cell division Cell membrane Cell projection Cilium Cilium biogenesis/degradation Cytoplasm Cytoskeleton Isopeptide bond Kinase Membrane Microtubule Mitosis Nucleotide-binding Phosphoprotein Proto-oncogene Reference proteome Serine/threonine-protein kinase Transferase Ubl conjugation | MDKCKENCIS | MDKCKENCISGLKTTVPPGDGPKRVPVTQHFPAQHLPSANSGQAQRVLCPSNSSQRLPSHTQKLVSSHKPVQNLKQKQSQATSGPRPVSRPLSNTQQSEQPQPAAPGNNPEKEAASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKTQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGAVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCY... | cell division cilium disassembly meiotic spindle organization mitotic centrosome separation mitotic spindle organization phosphorylation positive regulation of meiotic cell cycle process involved in oocyte maturation positive regulation of mitotic cell cycle positive regulation of translation regulation of cytokinesis ... |
Mo-molybdopterin cofactor biosynthetic process protein urmylation tRNA thio-modification tRNA wobble position uridine thiolation tRNA wobble uridine modification | cytoplasm; cytosol | ATP binding metal ion binding molybdopterin-synthase adenylyltransferase activity molybdopterin-synthase sulfurtransferase activity nucleotidyltransferase activity sulfurtransferase activity thiosulfate sulfurtransferase activity URM1 activating enzyme activity | Sus scrofa | ATP-binding Cytoplasm Disulfide bond Metal-binding Molybdenum cofactor biosynthesis Multifunctional enzyme Nucleotide-binding Reference proteome Transferase tRNA processing Zinc | MAAREEVLAL | MAAREEVLALQAEVARREEELSSLKHRLAAALLAEQESERLLPVSPLPPKAALSQDEILRYSRQLVLPELGVQGQLRLATASVLIVGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEVSNLARQVLHGEALAGQAKVFSAAASLRRLNSAVECVPYAQALTPATALDLVRRYDVVADCSDNVPTRYLVNDACVLAGRPLVSASALRFEGQITVYHYGGGPCYRCVFPQPPPAETVTNCADGGVLGVVTGVLGCLQALEVLKIAAGLGPSYSGSLLLFDALRGLFRRIQLRRRRPDCAACGERPTVTELQDYEGFCGSSATD... | Mo-molybdopterin cofactor biosynthetic process protein urmylation tRNA thio-modification tRNA wobble position uridine thiolation tRNA wobble uridine modification cytoplasm; cytosol ATP binding metal ion binding molybdopterin-synthase adenylyltransferase activity molybdopterin-synthase sulfurtransferase activity nucleot... |
hydrogen peroxide catabolic process response to oxidative stress | extracellular region; plant-type cell wall; vacuole | heme binding lactoperoxidase activity metal ion binding peroxidase activity | Zea mays | Calcium Disulfide bond Glycoprotein Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Pyrrolidone carboxylic acid Reference proteome Secreted Signal Vacuole | MAKESKLTAG | MAKESKLTAGVAAALTVVAACALCLLLPATARAQLRVGFYDTSCPNAEALVRQAVAAAFAKDAGIAAGLIRLHFHDCFVRGCDGSVLLTVNPGGGQTERDALPNNPSLRGFDVIDAAKTAVEQSCPRTVSCADIVAFAARDSISLTGSVSYQVPAGRRDGRVSNATETVDLPPPTSTAQSLTDLFKAKELSVEDMVVLSGAHTVGRSFCASFFKRVWNTSTNPATAIVDAGLSPSYAQLLRALCPSNTTQTTPITTAMDPGTPNVLDNNYYKLLPRGMGLFFSDNQLRVNPQMAALVSSFASNETLWKEKFAAAMVKMGR... | hydrogen peroxide catabolic process response to oxidative stress extracellular region; plant-type cell wall; vacuole heme binding lactoperoxidase activity metal ion binding peroxidase activity Zea mays Calcium Disulfide bond Glycoprotein Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Pyrrolidone ca... |
angiogenesis cell differentiation defense response to Gram-negative bacterium defense response to Gram-positive bacterium immune system process | extracellular region | endonuclease activity RNA binding RNA nuclease activity | Danio rerio | 3D-structure Angiogenesis Antibiotic Antimicrobial Developmental protein Differentiation Direct protein sequencing Disulfide bond Endonuclease Hydrolase Immunity Nuclease Pyrrolidone carboxylic acid Reference proteome Secreted Signal | MGIHQCTAVV | MGIHQCTAVVLLLLCASLSTYGQPAEIRRRYEHFLTQHVYGGITEQTCDRVMRQRRITRFPTGNDCKEVNTFIQANGNHVRTVCTGGGTRQTDNRDLYMSNNQFTVITCTLRSGERHPNCRYRGKESSRKIVVACEGEWPTHYEKGVIV | angiogenesis cell differentiation defense response to Gram-negative bacterium defense response to Gram-positive bacterium immune system process extracellular region endonuclease activity RNA binding RNA nuclease activity Danio rerio 3D-structure Angiogenesis Antibiotic Antimicrobial Developmental protein Differentiati... |
viral entry into host cell viral penetration into host nucleus | host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid | DNA binding | WU polyomavirus | Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane Host nucleus Late protein Lipoprotein Membrane Myristate Reference proteome Viral penetration into host nucleus Virion Virus entry into host cell | MGILLAVPEI | MGILLAVPEIIAASVAGGAEALSIAGSGAAIATGEGLAALGGLTESAALLGETVEISEAAATVLTKVPELVTVTQGVTAAVQGGAGLVGGIYTALAADRPGDLPASTPTGSPSGLHPPAGYNPQGGGLNIQSIHKPLHAPYPGMALAPIPEYNLETGIPGVPDWVFNFIASHLPELPSLQDVFNRIAYGIWTSYYNTGRTVVNRAVSEELQRLLGDLEYGFRTALATIGESDPVNAIVEQVRSFVSGGRQRELLQIAAGQPVDISEGVSRGTATISNAVEAVRDATQRLSQATYNFVYDASTLPRDGFNALSDGVHRLGQ... | viral entry into host cell viral penetration into host nucleus host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid DNA binding WU polyomavirus Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane Host nucleus Late protein Lipopro... |
B cell homeostasis B cell proliferation cell morphogenesis defense response to Gram-positive bacterium gene expression lymph node development negative regulation of T cell apoptotic process negative regulation of T cell mediated cytotoxicity positive regulation of cell population proliferation positive regulation of ge... | cytosol; external side of plasma membrane; nucleoplasm | cytokine receptor activity | Callithrix jacchus | Cell membrane Disulfide bond Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Signal Transmembrane Transmembrane helix | MTILGTTFGV | MTILGTTFGVFFSLLQVVSGESGYAQNGDLEDAELDDYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVRCLNFRKLQEIYLIETKKFLLIGNSNICVKAGEKSLTCKNVNVATIVKPEAPFDLSVIYREGANDFLVTFNTSHLQKKYVKVLMHDVAYRHEKDENNWMHVNLSSTKLTLLQRKLQPKATYEIKVRSIPGDYFKGFWSEWSPSYYFRTPEINNHSGETNPTLLTISILSVLSVVLLVILACVLWKKRIKPIIWPSLPDHKKTLEHLCKKPSKNLIVSFNPESFLDCQIHRVDDIQARDEV... | B cell homeostasis B cell proliferation cell morphogenesis defense response to Gram-positive bacterium gene expression lymph node development negative regulation of T cell apoptotic process negative regulation of T cell mediated cytotoxicity positive regulation of cell population proliferation positive regulation of ge... |
defense response to Gram-positive bacterium inflammatory response innate immune response MyD88-dependent toll-like receptor signaling pathway positive regulation of canonical NF-kappaB signal transduction positive regulation of non-canonical NF-kappaB signal transduction Toll signaling pathway toll-like receptor 4 sign... | cytoplasm; cytosol; nucleus; plasma membrane | TIR domain binding Toll-like receptor binding | Gallus gallus | Cytoplasm Immunity Inflammatory response Innate immunity Nucleus Reference proteome | MATVPVGAGS | MATVPVGAGSAPGPEPADLHSVPMVALNYGVRRRLGLYLNPRAATAADWTALAEKLGHDYLEIRRLEALPDPTAALLEEWQSRCPGGATVGQLLELLRQLGRHDVLLELGGSVEEDCKKYLRRKQQEAEQPLQVPAVDSSVPKTSELMGITTRDDPYGHGTEMFDAFICYCQKDLQFVQEMIRELEQTEFKLKLCVFDRDVLPGTCVWSISGELIERRCRRMVVVISDDYLESDECDFQTKFALSLSPGARLKRLIPVKCKTMKNEFPSILRFITICDYTNPCTKKWFWTRLAKSLLLP | defense response to Gram-positive bacterium inflammatory response innate immune response MyD88-dependent toll-like receptor signaling pathway positive regulation of canonical NF-kappaB signal transduction positive regulation of non-canonical NF-kappaB signal transduction Toll signaling pathway toll-like receptor 4 sign... |
positive regulation of catalytic activity positive regulation of spermidine biosynthetic process S-adenosylmethionine metabolic process spermidine biosynthetic process trypanothione biosynthetic process | catalytic complex | adenosylmethionine decarboxylase activity enzyme activator activity enzyme binding protein heterodimerization activity | Trypanosoma brucei brucei | 3D-structure Polyamine biosynthesis Spermidine biosynthesis | MSVTRINQQT | MSVTRINQQTECPSSVHDLVSCWGGCTQSKTSTDSGLEKRFELNFAQPVDIGTVTVKQLASVMERAGESLRQNSAELGIHTLKFDRSLLVFTAKQIVVRSSVSVMLHEAVHPMLELMRSHNIIVDWASFMRVNYGSPWDMTSETSDIMAHEYAELKSAFPTGHPYLAGPVDRDHCFYFVYDGIDRDPSSCRRENDVQINVYMYNVQADDEYDLDGNTKEQQLLVSHCAGEYETLRVSTYGSTHPFASFETNAVSAASDITKIVNGLLKKFYPERVLLVLLQDRDAQGTTACGVMDRLEGFTVVHRGANHFGGGYVFHQAT... | positive regulation of catalytic activity positive regulation of spermidine biosynthetic process S-adenosylmethionine metabolic process spermidine biosynthetic process trypanothione biosynthetic process catalytic complex adenosylmethionine decarboxylase activity enzyme activator activity enzyme binding protein heterodi... |
DNA repair protein repair | cytoplasm | protein deglycase activity thiolester hydrolase activity | Staphylococcus aureus | Cytoplasm DNA damage DNA repair Hydrolase Stress response | MSQDVNELSK | MSQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLSGYPVKLELWAMPTEDEAVISTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGHAAVVGISESEDVQQTLDWALDNDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVADLLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK | DNA repair protein repair cytoplasm protein deglycase activity thiolester hydrolase activity Staphylococcus aureus Cytoplasm DNA damage DNA repair Hydrolase Stress response MSQDVNELSK MSQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLSGYPVKLELWAMPTEDEAVISTYNKLKEKLKQPKK... |
antibacterial humoral response hydrogen peroxide catabolic process response to oxidative stress | cytoplasm; extracellular space | calcium ion binding heme binding lactoperoxidase activity peroxidase activity thiocyanate peroxidase activity | Bubalus bubalis | 3D-structure Antibiotic Antimicrobial Calcium Cytoplasm Disulfide bond Glycoprotein Heme Hydrogen peroxide Iron Metal-binding Nitration Oxidoreductase Peroxidase Phosphoprotein Secreted Signal | MWVCLQLPVF | MWVCLQLPVFLASVTLFEVAASDTIAQAASTTTISDAVSKVKIQVNKAFLDSRTRLKTTLSSEAPTTQQLSEYFKHAKGQTRTAIRNGQVWEESFKRLRRDTTLTNVTDPSLDLTALSWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRL... | antibacterial humoral response hydrogen peroxide catabolic process response to oxidative stress cytoplasm; extracellular space calcium ion binding heme binding lactoperoxidase activity peroxidase activity thiocyanate peroxidase activity Bubalus bubalis 3D-structure Antibiotic Antimicrobial Calcium Cytoplasm Disulfide b... |
response to oxidative stress | lipid droplet | alcohol dehydrogenase (NAD+) activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Caenorhabditis elegans | Alternative splicing Lipid droplet NAD Oxidoreductase Reference proteome | MPYVFLLSPQ | MPYVFLLSPQLEIASQWDGYYEKTFEVSDHVHKEIILKVSGQTVLITGSGSGLGRLMAFEFGKLGARLVLWDINEQGNKETLKELEAMGVEAKAYTVDLSEYKEINRTADLVKSEVGKVDILVNNAGIVTGKKLLQCPDELMVKTVSVNTNALFFTTKNFLPGMLESNKGHIVTIASMAGKCGVAGLVDYCASKHGAVGFNDSLASELYALKKDVKTTVVCPIYINTGMFDGIATKWPTLLPILSPEYVVDCIMEAVLTDRAFLAIPKFSYIFIALAGLLPTEVLNLYGDHFGITHSMDHFKGRQSRQA | response to oxidative stress lipid droplet alcohol dehydrogenase (NAD+) activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Caenorhabditis elegansAlternative splicing Lipid droplet NAD Oxidoreductase Reference proteome MPYVFLLSPQ MPYVFLLSPQLEIASQWDGYYEKTFEVSDHVHKEIILKVSGQTVLIT... |
proteolysis | endoplasmic reticulum membrane | aspartic-type endopeptidase activity | Plasmodium vivax | 3D-structure Aspartyl protease Disulfide bond Endoplasmic reticulum Hydrolase Membrane Protease Reference proteome Signal Transmembrane Transmembrane helix | MVGASLGPPG | MVGASLGPPGRGSLSRLIRLVICVLTLCALSVQGRSESTEGHSKDLLYKYKLYGDIDEYAYYFLDIDIGTPEQRISLILDTGSSSLSFPCAGCKNCGVHMENPFNLNNSKTSSILYCENEECPFKLNCVKGKCEYMQSYCEGSQISGFYFSDVVSVVSYNNERVTFRKLMGCHMHEESLFLYQQATGVLGMSLSKPQGIPTFVNLLFDNAPQLKQVFTICISENGGELIAGGYDPAYIVRRGGSKSVSGQGSGPVSESLSESGEDPQVALREAEKVVWENVTRKYYYYIKVRGLDMFGTNMMSSSKGLEMLVDSGSTFTH... | proteolysis endoplasmic reticulum membrane aspartic-type endopeptidase activity Plasmodium vivax 3D-structure Aspartyl protease Disulfide bond Endoplasmic reticulum Hydrolase Membrane Protease Reference proteome Signal Transmembrane Transmembrane helix MVGASLGPPG MVGASLGPPGRGSLSRLIRLVICVLTLCALSVQGRSESTEGHSKDLLYKYKLYGDI... |
peptide catabolic process proteolysis | cytoplasm | manganese ion binding metalloaminopeptidase activity metallodipeptidase activity zinc ion binding | Plasmodium vivax | 3D-structure Aminopeptidase Cytoplasm Dipeptidase Hydrolase Metal-binding Protease Reference proteome Zinc | MPLLRSSQHI | MPLLRSSQHIKNTYWNIPKKSFRTGVPQFAESKKTRILHLHPLCKSASGVESPPFFDSQTFSSISNRKEFRKMATTVPQVVSLDPTTIPIDYHTPIDDLSIEVKDISAEACPADEGLIVFLLNSAPKHSSSGGSGGNGGSAGSSGNGEGGAQIKINSSVKDNTINEFLKEGNMENFTGKLGTSKSFYIANDQKKYVSLAYVGCGPANEETELEIRKVAYALVTLLHDSKHKKVSIIFEIKIEEALFRFFLEHLFYEYVTDERFKSADKSTETDFIKNLSLHIANADAYKGQIDKARVYFYGTYYAAQLIAAPSNYCNPVS... | peptide catabolic process proteolysis cytoplasm manganese ion binding metalloaminopeptidase activity metallodipeptidase activity zinc ion binding Plasmodium vivax 3D-structure Aminopeptidase Cytoplasm Dipeptidase Hydrolase Metal-binding Protease Reference proteome Zinc MPLLRSSQHI MPLLRSSQHIKNTYWNIPKKSFRTGVPQFAESKKTRILH... |
phenylalanyl-tRNA aminoacylation protein heterotetramerization | cytoplasm; cytosol; phenylalanine-tRNA ligase complex | ATP binding magnesium ion binding phenylalanine-tRNA ligase activity RNA binding | Plasmodium vivax | 3D-structure Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Ligase Magnesium Metal-binding Nucleotide-binding Protein biosynthesis Reference proteome | MPTISVHEED | MPTISVHEEDLIEKLGEKIEEEKLNDICFEFGIEIDDVEYKGEKKIYKIEVPANRYDLVCVEGLCRALKSFIGKYENVSYALLTNSEEACVKEKHFMRVDESVDERRSYVVSAVLKNVKMNENVYNNIIELQEKLHHNLGKKRILLAIGIHDYDKINFPVAYKFEEKEKINFIPLNETQNVNGNNFINFYQDNINLKSYLKIISDFEKFPVIVDAGGQILSLPPIINCDYTKITYDTRNLFIECTAIDRNKAEIAVNIICSMLSEYCTPKYSIHSFFVQYDKNHKAEKGNGYLYPVFKNKTLTCHMDYVRKLSGILNLSV... | phenylalanyl-tRNA aminoacylation protein heterotetramerization cytoplasm; cytosol; phenylalanine-tRNA ligase complex ATP binding magnesium ion binding phenylalanine-tRNA ligase activity RNA binding Plasmodium vivax 3D-structure Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Ligase Magnesium Metal-binding Nucleotide-bi... |
phenylalanyl-tRNA aminoacylation protein heterotetramerization | cytoplasm; cytosol; phenylalanine-tRNA ligase complex | ATP binding magnesium ion binding phenylalanine-tRNA ligase activity tRNA binding | Plasmodium vivax | 3D-structure Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Ligase Magnesium Metal-binding Nucleotide-binding Protein biosynthesis Reference proteome | MQAKAQEEQK | MQAKAQEEQKGEELSQFLQALEEEFALCQEGGGDKREADGPSLENAEAEELANRRAYYLQLKEERNVLVEESKHVTSLHMSSKHNIEHAKVLGMAKKLETLYYVVNHVRSFNTYQLTEEGKEYLRDGSPEHVTLRYVMEQEGCTLEDLKKLFGKKGEIGLNINLKKKKIELRKSDKRLFPHVEGSAHSLVDETRCYLQKVEAHGNDEGALVSHLKGILPPEKGEKKEEDEANNLIKELKKRKLIEAKKISYIYIIRTNLFTKEIKKQITDLTYLLIKNEEYKKYQVKKYNFFSSGKKMNKGNIHLLIRQMRTFKDVFVSL... | phenylalanyl-tRNA aminoacylation protein heterotetramerization cytoplasm; cytosol; phenylalanine-tRNA ligase complex ATP binding magnesium ion binding phenylalanine-tRNA ligase activity tRNA binding Plasmodium vivax 3D-structure Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Ligase Magnesium Metal-binding Nucleotide-b... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of heart rate regulation of systemic arterial blood pressure regulation of urine volume | extracellular region | hormone activity | Sus scrofa | Amidation Cleavage on pair of basic residues Disulfide bond Hormone Reference proteome Secreted Signal | MTAHILLLWL | MTAHILLLWLFASSILGDPDSAGRLTRHQVSLKSGRLCSLGTCQTHRLPEIIYWLRSASTKELSGKAGRKPQDPYSYGRRRRRRRRRREARLLRRLQDPSLRRAQLAG | adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of heart rate regulation of systemic arterial blood pressure regulation of urine volume extracellular region hormone activity Sus scrofa Amidation Cleavage on pair of basic residues Disulfide bond Hormone Reference proteome Se... |
CD8-positive, alpha-beta T cell differentiation proteasomal protein catabolic process proteolysis T cell differentiation in thymus | cytosol; nucleus; proteasome core complex, beta-subunit complex | endopeptidase activity peptidase activity threonine-type endopeptidase activity | Homo sapiens | Cytoplasm Hydrolase Nucleus Protease Proteasome Reference proteome Threonine protease Zymogen | MALQDVCKWQ | MALQDVCKWQSPDTQGPSPHLPRAGGWAVPRGCDPQTFLQIHGPRLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESGWEHVSRSDACVLYVELQKLLEPEPEEDASHAHPEPATAHRAAEDRELSVGPGEVTPGDSRMPAGTETV | CD8-positive, alpha-beta T cell differentiation proteasomal protein catabolic process proteolysis T cell differentiation in thymus cytosol; nucleus; proteasome core complex, beta-subunit complex endopeptidase activity peptidase activity threonine-type endopeptidase activity Homo sapiens Cytoplasm Hydrolase Nucleus Prot... |
ganglioside catabolic process oligosaccharide catabolic process | cytoplasm; cytoplasmic vesicle; lysosomal lumen; lysosomal membrane; lysosome; membrane; plasma membrane | exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity exo-alpha-sialidase activity | Sus scrofa | Carbohydrate metabolism Cell membrane Cytoplasmic vesicle Glycoprotein Glycosidase Hydrolase Lipid degradation Lipid metabolism Lysosome Membrane Phosphoprotein Reference proteome Repeat Signal | MTAERPGAVP | MTAERPGAVPLGRPGRPPMLGLGEAYRAQVFASIFLLLLSPAGVGARAKNDFNLVHPLVTMEQLLWVSGKQIGSVDTFRIPLITTTPRGTLLAFAEARKMSASDKGAKFIALRRSMDQGSTWSPTAFIVDDGETPDGLNLGAVVSDTTTGVVFLFYSLCAHKAGCRVASTMLVWSKDDGISWSSPRNLSLDIGTEMFAPGPGSGIQKQWAPQKGRLIVCGHGTLERDGVFCLLSDDHGASWRYGSGISGIPYGQPKRENDFNPDECQPYELPDGSVVINARNQNNYHCRCRIVLRSYDACDTLRPRDVTFDPELVDPVVA... | ganglioside catabolic process oligosaccharide catabolic process cytoplasm; cytoplasmic vesicle; lysosomal lumen; lysosomal membrane; lysosome; membrane; plasma membrane exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity exo-alpha-sialidase activity Sus scrofa Car... |
cell redox homeostasis intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress protein folding protein folding in endoplasmic reticulum release of sequestered calcium ion into cytosol response to endoplasmic reticulum stress | dendrite; endoplasmic reticulum; endoplasmic reticulum membrane; extracellular space; Golgi lumen | FAD binding oxidoreductase activity protein-disulfide reductase activity thiol oxidase activity | Bos taurus | Apoptosis Cell projection Disulfide bond Electron transport Endoplasmic reticulum FAD Flavoprotein Glycoprotein Golgi apparatus Membrane Oxidoreductase Phosphoprotein Redox-active center Reference proteome Secreted Signal Transport | MGRRWGFLIG | MGRRWGFLIGFLVAVGLLGLGHGEQQPSETAAQRCFCQVSGYLDDCTCDVETIDKFNNYRLFPRLQKLLESDYFRYYKVNLKRPCPFWNDINQCGRRDCAVKPCHSDEVPDGIKSASYKYSEEANNLIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEVDDIQSPDAEYVDLLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGKSEENTFYSWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQDTWLEKKWGHNITEFQQRFDGILTEGEGPRRLKNLYFLYLIELRALSKVVP... | cell redox homeostasis intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress protein folding protein folding in endoplasmic reticulum release of sequestered calcium ion into cytosol response to endoplasmic reticulum stress dendrite; endoplasmic reticulum; endoplasmic reticulum membrane; extr... |
cell division cellular response to ionizing radiation chromatin remodeling DNA repair-dependent chromatin remodeling double-strand break repair mitotic G2 DNA damage checkpoint signaling positive regulation of DNA repair positive regulation of NLRP3 inflammasome complex assembly protein K63-linked deubiquitination prot... | BRCA1-A complex; BRISC complex; cytoplasm; nuclear ubiquitin ligase complex; nucleoplasm; nucleus; spindle pole | cysteine-type deubiquitinase activity enzyme regulator activity K63-linked deubiquitinase activity metal ion binding metal-dependent deubiquitinase activity metallopeptidase activity polyubiquitin modification-dependent protein binding | Bos taurus | Acetylation Alternative splicing Cell cycle Cell division Chromatin regulator Cytoplasm Cytoskeleton DNA damage DNA repair Hydrolase Metal-binding Metalloprotease Mitosis Nucleus Phosphoprotein Protease Reference proteome Ubl conjugation pathway Zinc | MAVQVVQAVQ | MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDLRNDPKFTYTGTEMRTVAEKVDTVRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSESPRGPRDFWSSSQHISIEGQKEEERYERIEIPIHIVPHVTIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHVQELQQEKEELLQELSSLE | cell division cellular response to ionizing radiation chromatin remodeling DNA repair-dependent chromatin remodeling double-strand break repair mitotic G2 DNA damage checkpoint signaling positive regulation of DNA repair positive regulation of NLRP3 inflammasome complex assembly protein K63-linked deubiquitination prot... |
autophagy cellular response to interleukin-1 DNA damage response DNA damage response, signal transduction by p53 class mediator DNA repair monoubiquitinated protein deubiquitination negative regulation of canonical NF-kappaB signal transduction negative regulation of stress granule assembly protein deubiquitination pro... | cytoplasm; cytosolic ribosome; early endosome; intermediate filament cytoskeleton; nucleoplasm; nucleus; protein-containing complex | cysteine-type deubiquitinase activity cysteine-type endopeptidase activity molecular function inhibitor activity p53 binding transmembrane transporter binding | Bos taurus | Acetylation Autophagy Cytoplasm DNA damage DNA repair Endosome Hydrolase Nucleus Phosphoprotein Protease Reference proteome Thiol protease Ubl conjugation Ubl conjugation pathway | MALRSPQYIF | MALRSPQYIFGDFSPDEFNQFFVTPRASVELPPYGGTVLCGAQAADDLPDGHDYQRIEFGVNEVIEPSDTLPRTPNYSISSTLNPQAPEFILSCTTSKKLPDDIDKEVNYSSANCQYPGPALALDGGSPAEAEALENDGVSGGLGQRERKKKKKRPPGYYSYLKDGGEGGPSAEALVNGHAGPAVSNSVGAEDTDLMGDVPTAGTPRTWGSPQDATDFVSDAGPAGAFPGALDGGARTAGQLEGCPGADSEASCLPAEAGRDTLLRTAVAQPSVGTDTTENLGVTNGQILESLGEGTAANGVELHTVESSDSDPAKAESA... | autophagy cellular response to interleukin-1 DNA damage response DNA damage response, signal transduction by p53 class mediator DNA repair monoubiquitinated protein deubiquitination negative regulation of canonical NF-kappaB signal transduction negative regulation of stress granule assembly protein deubiquitination pro... |
adenine nucleotide transport ADP transport ATP transport | mitochondrial inner membrane | adenine nucleotide transmembrane transporter activity ADP:inorganic phosphate antiporter activity ATP transmembrane transporter activity ATP:inorganic phosphate antiporter activity calcium ion binding | Bos taurus | Acetylation Antiport Calcium Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport | MLRWLRGFVL | MLRWLRGFVLPTAACQDVEPPTRYETLFQKLDRNGDGVVDISELQEGLKSLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQILGLTISEQQAELILQSIDADGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGVAGAVSRTSTAPLDRLKVMMQVHGSKSAKMNIYGGFQQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFVSGSMAGATAQTFIYPMEVLKTRLAVGK... | adenine nucleotide transport ADP transport ATP transport mitochondrial inner membrane adenine nucleotide transmembrane transporter activity ADP:inorganic phosphate antiporter activity ATP transmembrane transporter activity ATP:inorganic phosphate antiporter activity calcium ion binding Bos taurus Acetylation Antiport C... |
cellular defense response galactolipid catabolic process intestinal lipid catabolic process phospholipid catabolic process phospholipid metabolic process response to bacterium triglyceride catabolic process | extracellular space; neuron projection; zymogen granule membrane | 1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity acylglycerol lipase activity calcium ion binding galactolipase activity phospholipase activity triglyceride lipase activity | Bos taurus | Calcium Cell projection Cytoplasmic vesicle Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metabolism Membrane Metal-binding Reference proteome Secreted Signal | MLPSWTIGLL | MLPSWTIGLLLLATVRGKEICYEPFGCFSDEKPWTGILQRPLKLFPWSPEDIDAHFLLYTNENPNNYQRINITDLATVRASNFQLDRKTRFVIHGFIDDGDSGWPTDLCKKMFKVEKVNCICVDWEHGAWTKYTQAVHNTRVVGAEIAFFIQGLSTELGYGPENVHLIGHSLGAQLAAEAGRRLGGQVGRITGLDPAQPCFEGTPEEVRLDPSDAMFVDVIHTDSASIIPFLSLGIRQKVGHLDFYPNGGKEMPGCQKNILSTIIDINGIWQGIQDFVACSHLRSYKYYSSSILNPDGFLGYPCASYEEFQEGGCFPCPA... | cellular defense response galactolipid catabolic process intestinal lipid catabolic process phospholipid catabolic process phospholipid metabolic process response to bacterium triglyceride catabolic process extracellular space; neuron projection; zymogen granule membrane 1-18:1-2-16:0-monogalactosyldiacylglycerol lipas... |
negative regulation of DNA-templated transcription negative regulation of osteoblast differentiation | nucleolus; nucleoplasm; nucleus | 2-oxoglutarate-dependent dioxygenase activity histone H3K36 demethylase activity histone H3K36me/H3K36me2 demethylase activity histone H3K4 demethylase activity histone H3K4me/H3K4me2/H3K4me3 demethylase activity iron ion binding peptidyl-histidine dioxygenase activity protein demethylase activity | Bos taurus | Acetylation Chromatin regulator Dioxygenase Iron Metal-binding Nucleus Oxidoreductase Phosphoprotein Reference proteome Repressor Transcription Transcription regulation | MDGLRASAGL | MDGLRASAGLLRRGRLRRRRQQQPHSGSVLALPLRPRKIRRQLRRSVSSRMAALRAQTLQSEDSEDSRVESTVGEPGDPLAGGTAALSDATGREPHGQLGPVELLEASPASRSLQTPRALVEAQTPAARLVEAQTPAARLVEAHTPAARLVEAHTPPARLVEASALPARLVETSALLCSTQHLAAVPPSVAPAMLSGPQGESTGEELPWDSPLQRILAELNRIPSSRRRAARLFEWLISPMPPDHFYRRLWEREAVLVRRQDHSYYQGLFSTAVLDSILRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYRA... | negative regulation of DNA-templated transcription negative regulation of osteoblast differentiation nucleolus; nucleoplasm; nucleus 2-oxoglutarate-dependent dioxygenase activity histone H3K36 demethylase activity histone H3K36me/H3K36me2 demethylase activity histone H3K4 demethylase activity histone H3K4me/H3K4me2/H3K... |
calcineurin-NFAT signaling cascade cell cycle cell differentiation cellular response to hydrogen peroxide cellular response to laminar fluid shear stress cellular response to transforming growth factor beta stimulus intracellular signal transduction MAPK cascade negative regulation of calcineurin-NFAT signaling cascade... | cytoplasm; cytosol; nucleus; PML body | ATP binding MAP kinase activity mitogen-activated protein kinase binding protein serine kinase activity protein serine/threonine kinase activity | Bos taurus | Acetylation ATP-binding Cell cycle Cytoplasm Differentiation Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MAEPLKEDDG | MAEPLKEDDGEDGSGEPPGPVKAEPAGTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMTVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQA... | calcineurin-NFAT signaling cascade cell cycle cell differentiation cellular response to hydrogen peroxide cellular response to laminar fluid shear stress cellular response to transforming growth factor beta stimulus intracellular signal transduction MAPK cascade negative regulation of calcineurin-NFAT signaling cascade... |
neuron projection development regulation of ARF protein signal transduction signal transduction | cleavage furrow; dendritic spine; postsynaptic density, intracellular component; ruffle membrane | guanyl-nucleotide exchange factor activity phospholipid binding | Homo sapiens | Alternative splicing Cell membrane Cell projection Coiled coil Guanine-nucleotide releasing factor Membrane Phosphoprotein Reference proteome | MAQGAMRFCS | MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGRELGRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAPGGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAPPQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKWEFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETDIDEVLAEREEADSAIESQPS... | neuron projection development regulation of ARF protein signal transduction signal transduction cleavage furrow; dendritic spine; postsynaptic density, intracellular component; ruffle membrane guanyl-nucleotide exchange factor activity phospholipid binding Homo sapiens Alternative splicing Cell membrane Cell projection... |
ether lipid biosynthetic process fatty acid metabolic process | endoplasmic reticulum; endoplasmic reticulum membrane | plasmanylethanolamine desaturase activity | Homo sapiens | Alternative splicing Endoplasmic reticulum Fatty acid metabolism Lipid metabolism Membrane Oxidoreductase Reference proteome Transmembrane Transmembrane helix | MAGAENWPGQ | MAGAENWPGQQLELDEDEASCCRWGAQHAGARELAALYSPGKRLQEWCSVILCFSLIAHNLVHLLLLARWEDTPLVILGVVAGALIADFLSGLVHWGADTWGSVELPIVGKAFIRPFREHHIDPTAITRHDFIETNGDNCLVTLLPLLNMAYKFRTHSPEALEQLYPWECFVFCLIIFGTFTNQIHKWSHTYFGLPRWVTLLQDWHVILPRKHHRIHHVSPHETYFCITTGWLNYPLEKIGFWRRLEDLIQGLTGEKPRADDMKWAQKIK | ether lipid biosynthetic process fatty acid metabolic process endoplasmic reticulum; endoplasmic reticulum membrane plasmanylethanolamine desaturase activity Homo sapiens Alternative splicing Endoplasmic reticulum Fatty acid metabolism Lipid metabolism Membrane Oxidoreductase Reference proteome Transmembrane Transmembr... |
central nervous system morphogenesis cranial skeletal system development endocytosis protein deubiquitination protein K48-linked deubiquitination protein K63-linked deubiquitination proteolysis regulation of G protein-coupled receptor signaling pathway | centrosome; perinuclear region of cytoplasm | cysteine-type deubiquitinase activity cysteine-type endopeptidase activity zinc ion binding | Danio rerio | Cytoplasm Cytoskeleton Endocytosis Hydrolase Metal-binding Protease Reference proteome Repeat Thiol protease Ubl conjugation pathway Zinc Zinc-finger | MTDSGDLCPH | MTDSGDLCPHLDSIGEVTKEELIQKSKGTCQSCGVGGPNLWACLQCDCPYVGCGESYSDHSTIHAQAKKHNLTVNLTTFRVWCYVCEREVFLEPKPVTPVSSAHRCKPHDQDPVSQTTCYPLKAVPIAVADEEGSESEEDELKPRGLTGMKNIGNSCYMNAALQALSNCPPLTQFFQDCSGLVRTDKKPALCKSYQKLISELWHKKRPSYVVPTTLFHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELKEPLFDCSGGISEVEPDLSLDSCNLVDGDRSPSEDEFLSCDSGSGSERGDGERAGGEAELLIQDECVAVR... | central nervous system morphogenesis cranial skeletal system development endocytosis protein deubiquitination protein K48-linked deubiquitination protein K63-linked deubiquitination proteolysis regulation of G protein-coupled receptor signaling pathway centrosome; perinuclear region of cytoplasm cysteine-type deubiquit... |
extracellular matrix organization otolith development otolith mineralization protein complex oligomerization | collagen trimer; collagen-containing extracellular matrix; extracellular space | calcium ion binding extracellular matrix structural constituent conferring tensile strength | Danio rerio | Calcium Collagen Disulfide bond Extracellular matrix Glycoprotein Metal-binding Reference proteome Repeat Secreted Signal | MPNILHPFII | MPNILHPFIIIMTLLVVATGNQASIDKTTQWPRMKPTKKPPPRDEGPSKLGSISTTVSPTAIGITEEVTDAMMDAYTITSTGSTTFSSDTYSADYHTEAMVPPGVGPGNYTLDYNECFFNFCECCPPERGPPGPVGEKGLPGIPGGKGEMGPPGPPGQEGLTGAPGTHGVKGEKGDTGASGLPGIPGVTGKQGEKGESGPKGDKGDTGFPGLKGDPGERGEPGWNGTKGGMGEPGKQGLTGPPGPDGIKGEKGDKGDCPFGEKGQKGSIGEPGPQGPKGDPGVPGTNGTDGLPGSKGPKGDPGPLSKQGEPGPPGPQGPP... | extracellular matrix organization otolith development otolith mineralization protein complex oligomerization collagen trimer; collagen-containing extracellular matrix; extracellular space calcium ion binding extracellular matrix structural constituent conferring tensile strength Danio rerio Calcium Collagen Disulfide ... |
phosphorylation regulation of primary metabolic process | plasma membrane | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Mycobacterium tuberculosis | ATP-binding Cell membrane Kinase Membrane Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Transmembrane Transmembrane helix | MSPRVGVTLS | MSPRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVLKSEFSSDPEFIERFRAEARTTAMLNHPGIASVHDYGESQMNGEGRTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTGRALQIAHAAGLVHRDVKPGNILITPTGQVKITDFGIAKAVDAAPVTQTGMVMGTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKRPFAGDGALTVAMKHIKEPPPPLPPDLPPNVRELIEITLVKNPAMRYRSGGPFADAVAAVRAGRRPPRPSQTPPPGRAAPAAIPSGTTARVAANSAGRTAASRRSR... | phosphorylation regulation of primary metabolic process plasma membrane ATP binding protein serine kinase activity protein serine/threonine kinase activity Mycobacterium tuberculosis ATP-binding Cell membrane Kinase Membrane Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferas... |
beta-lactam antibiotic catabolic process response to antibiotic | extracellular region; periplasmic space | beta-lactamase activity | Mycobacterium tuberculosis | Antibiotic resistance Hydrolase Periplasm Reference proteome Secreted Signal | MRNRGFGRRE | MRNRGFGRRELLVAMAMLVSVTGCARHASGARPASTTLPAGADLADRFAELERRYDARLGVYVPATGTTAAIEYRADERFAFCSTFKAPLVAAVLHQNPLTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGPGGGTAAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRALLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDRAGGGYDAEPREALLAEAATCVAGVLA | beta-lactam antibiotic catabolic process response to antibiotic extracellular region; periplasmic space beta-lactamase activity Mycobacterium tuberculosis Antibiotic resistance Hydrolase Periplasm Reference proteome Secreted Signal MRNRGFGRRE MRNRGFGRRELLVAMAMLVSVTGCARHASGARPASTTLPAGADLADRFAELERRYDARLGVYVPATGTTAAIEYRAD... |
chromosome condensation intracellular iron ion homeostasis | cytoplasm; nucleoid | DNA binding oxidoreductase activity structural constituent of chromatin | Mycobacterium tuberculosis | 3D-structure Acetylation Cytoplasm DNA condensation DNA-binding Iron Iron storage Oxidoreductase Phosphoprotein Reference proteome Repeat Transcription Transcription regulation | MNKAELIDVL | MNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFRPGAQFKAVVSGAQRLPAEGPAVKRGVGASAAKKVAKKAPAKKATKAAKKAATKAPARKAATKAPAKKAATKAPAKKAVKATKSPAKKVTKAVKKTAVKASVRKAATKAPAKKAAAKRPATKAPAKKATARRGRK | chromosome condensation intracellular iron ion homeostasis cytoplasm; nucleoid DNA binding oxidoreductase activity structural constituent of chromatin Mycobacterium tuberculosis 3D-structure Acetylation Cytoplasm DNA condensation DNA-binding Iron Iron storage Oxidoreductase Phosphoprotein Reference proteome Repeat Tran... |
alanine biosynthetic process pantothenate biosynthetic process response to antibiotic | cytoplasm | aspartate 1-decarboxylase activity | Mycobacterium tuberculosis | Antibiotic resistance Autocatalytic cleavage Cytoplasm Decarboxylase Lyase Pantothenate biosynthesis Pyruvate Reference proteome Schiff base Zymogen | MLRTMLKSKI | MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVHPGDLVILIAYATMDDARARTYQPRIVFVDAYNKPIDMGHDPAFVPENAGELLDPRLGVG | alanine biosynthetic process pantothenate biosynthetic process response to antibiotic cytoplasm aspartate 1-decarboxylase activity Mycobacterium tuberculosis Antibiotic resistance Autocatalytic cleavage Cytoplasm Decarboxylase Lyase Pantothenate biosynthesis Pyruvate Reference proteome Schiff base Zymogen MLRTMLKSKI ML... |
axonogenesis habituation regulation of ERK1 and ERK2 cascade regulation of neurotrophin TRK receptor signaling pathway | cell projection; cytoplasmic vesicle membrane; Golgi membrane; presynaptic membrane | palmitoyltransferase activity protein-cysteine S-myristoyltransferase activity protein-cysteine S-palmitoyltransferase activity protein-cysteine S-stearoyltransferase activity | Danio rerio | Acyltransferase ANK repeat Cell membrane Cell projection Cytoplasmic vesicle Golgi apparatus Lipoprotein Membrane Palmitate Reference proteome Repeat Synapse Transferase Transmembrane Transmembrane helix | MADALVGYEK | MADALVGYEKEAGCVPILHPEEIKPQSHYNHGYNESRKSHVDDYSTWDIVKATQYGIFERCRELVEAGYDVRQPDKENVTLLHWAAINNRVDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCVHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEANANVDAQNIKGETPLDLAKQRKNVWMINHLQEARQAKGYDSPSYLKRLKMDKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKG... | axonogenesis habituation regulation of ERK1 and ERK2 cascade regulation of neurotrophin TRK receptor signaling pathway cell projection; cytoplasmic vesicle membrane; Golgi membrane; presynaptic membrane palmitoyltransferase activity protein-cysteine S-myristoyltransferase activity protein-cysteine S-palmitoyltransferas... |
inorganic cation transmembrane transport serotonin receptor signaling pathway | neuron projection; plasma membrane; postsynaptic membrane; serotonin-activated cation-selective channel complex; synapse | acetylcholine-gated monoatomic cation-selective channel activity serotonin-gated monoatomic cation channel activity | Homo sapiens | Alternative splicing Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MEGSWFHRKR | MEGSWFHRKRFSFYLLLGFLLQGRGVTFTINCSGFGQHGADPTALNSVFNRKPFRPVTNISVPTQVNISFAMSAILDVNEQLHLLSSFLWLEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQTHGEWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPVKSGNRVPFKITLLLGYNVFLLMMSDLLPTSGTPLIGVYFALCLSLMV... | inorganic cation transmembrane transport serotonin receptor signaling pathway neuron projection; plasma membrane; postsynaptic membrane; serotonin-activated cation-selective channel complex; synapse acetylcholine-gated monoatomic cation-selective channel activity serotonin-gated monoatomic cation channel activity Homo ... |
alpha-pinene biosynthetic process circadian rhythm diterpenoid biosynthetic process green leaf volatile biosynthetic process limonene biosynthetic process monoterpene biosynthetic process | chloroplast | (E)-beta-ocimene synthase activity 1,8-cineole synthase activity magnesium ion binding myrcene synthase activity sabinene synthase activity | Nicotiana suaveolens | Chloroplast Lyase Magnesium Metal-binding Plastid Transit peptide | MNHHLIITPI | MNHHLIITPIFHLQIMLPVATLKRPPPPAATCSIYSFSRGTPSLVSKARLSTAAVGGMKNEPSPNHYSDISSSDLNLTRRSGNYGPTMWDFEYIQSIHNDYTEKKYMNRLNKLKEEMKKMIMAEGSQELEKLELIDNLQRLGVSYHFKHEIMQILSSIKQHSTPADSLYATALKFRLFREYGFHISQEIFGGLSETHTEDTKGMLYLYEASFLATEGESELEKARNWTEKHLREYLENKNDDQNVAELVHHALELPLHWRMLRIEARWFINFYKKKQDMIPLLLELAILDFNIVQAAHIEDLKYVARWWKETCLAENLPF... | alpha-pinene biosynthetic process circadian rhythm diterpenoid biosynthetic process green leaf volatile biosynthetic process limonene biosynthetic process monoterpene biosynthetic process chloroplast (E)-beta-ocimene synthase activity 1,8-cineole synthase activity magnesium ion binding myrcene synthase activity sabinen... |
carnosine biosynthetic process histidine catabolic process | cytosol | ATP binding ATP hydrolysis activity carnosine synthase activity homocarnosine synthase activity metal ion binding | Homo sapiens | Alternative splicing ATP-binding Ligase Magnesium Manganese Metal-binding Nucleotide-binding Reference proteome | MLLCLSPAWL | MLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLDDFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQGGVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQVAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDGPSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGEEAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRA... | carnosine biosynthetic process histidine catabolic process cytosol ATP binding ATP hydrolysis activity carnosine synthase activity homocarnosine synthase activity metal ion binding Homo sapiens Alternative splicing ATP-binding Ligase Magnesium Manganese Metal-binding Nucleotide-binding Reference proteome MLLCLSPAWL MLL... |
proteolysis | extracellular region | cysteine-type peptidase activity | Tabernaemontana divaricata | 3D-structure Disulfide bond Hydrolase Protease Secreted Thiol protease Zymogen | AVIPLKNQGK | AVIPLKNQGKCGSCWAFSTVTTVESINQIRTGNLISLSEQQLVDCSKKNHGCKGGYFDRAYQYIIANGGIDTEANYPYKAFQGPCRAAKKVVRIDGCKGVPQCNENALKNAVASQPSVVAIDASSKQFQHYKSGIFTGPCGTKLNHGVVIVGYGKDYWIVRNSWGRHWGEQGYTRMKRVGGCGL | proteolysis extracellular region cysteine-type peptidase activity Tabernaemontana divaricata 3D-structure Disulfide bond Hydrolase Protease Secreted Thiol protease Zymogen AVIPLKNQGK AVIPLKNQGKCGSCWAFSTVTTVESINQIRTGNLISLSEQQLVDCSKKNHGCKGGYFDRAYQYIIANGGIDTEANYPYKAFQGPCRAAKKVVRIDGCKGVPQCNENALKNAVASQPSVVAIDASSKQFQHYKSGIF... |
cell adhesion mediated by integrin cellular response to low-density lipoprotein particle stimulus integrin-mediated signaling pathway muscle organ development myoblast differentiation myoblast fusion negative regulation of vasoconstriction positive regulation of cell migration positive regulation of protein localizatio... | cell surface; focal adhesion; integrin alpha9-beta1 complex; lamellipodium; melanosome; membrane; recycling endosome; ruffle membrane | integrin binding involved in cell-matrix adhesion metal ion binding protein heterodimerization activity | Camelus bactrianus | Acetylation Calcium Cell adhesion Cell junction Cell membrane Cell projection Disulfide bond EGF-like domain Endosome Glycoprotein Integrin Isopeptide bond Magnesium Membrane Metal-binding Myogenesis Phosphoprotein Receptor Repeat Signal Transmembrane Transmembrane helix Ubl conjugation | MNLQLIFWIG | MNLQLIFWIGLISSVCCVFGQADEDRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCHPNDTENPRGSKDIKKNKNVTNRSKGTAEKLQPEDITQIQPQQLVLQLRSGEPQTFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLRNPCTNEQNCTSPFSYKNVLSLTDKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQCHLKNDVYTMSHYYDYPSIA... | cell adhesion mediated by integrin cellular response to low-density lipoprotein particle stimulus integrin-mediated signaling pathway muscle organ development myoblast differentiation myoblast fusion negative regulation of vasoconstriction positive regulation of cell migration positive regulation of protein localizatio... |
ganglioside catabolic process oligosaccharide catabolic process | cytoplasm; cytoplasmic vesicle; lysosomal lumen; lysosomal membrane; lysosome; membrane; plasma membrane | exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity exo-alpha-sialidase activity | Bos taurus | Carbohydrate metabolism Cell membrane Cytoplasmic vesicle Glycoprotein Glycosidase Hydrolase Lipid degradation Lipid metabolism Lysosome Membrane Phosphoprotein Reference proteome Repeat Signal | MTEEGPGIVS | MTEEGPGIVSLGKLRRPRMLRLWGICRVQIFSAIFMLMSPAGVGAGAKDDFSLVHPLVTMEQLLWVSGKQIGSVDTFRIPLITTTPRGTLLAFAEARKMSTSDKGAKFIALRRSMDQGSTWSPTAFIVDDGETPDGLNLGAVVSDTTTGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVSWSSPRNLSLDIGTEMFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGVSWRYGGGVSGIPYGQPKRENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIILRSYDACDTLRPRDVTFDTELVDPVVAA... | ganglioside catabolic process oligosaccharide catabolic process cytoplasm; cytoplasmic vesicle; lysosomal lumen; lysosomal membrane; lysosome; membrane; plasma membrane exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity exo-alpha-sialidase activity Bos taurus Car... |
endocytosis megakaryocyte development protein transport regulation of protein localization | early endosome; Golgi apparatus; nucleus | GTPase activator activity small GTPase binding | Mus musculus | Alternative splicing Endocytosis Endosome Golgi apparatus GTPase activation Phosphoprotein Protein transport Reference proteome Transport | MEVRASFQKV | MEVRASFQKVSGSSDSVATLNSEEFVLVSQHTDATSIKDDGKPQLKIASNGDEQLEKAMEEILRDSEKGQSGLPVDCQGSSEISDCPFGDVPASQTTKPPLQLILDPSNTEISTPRPSSPSRFPEEDSVLFNKLTYLGCMKVSSPRSEVEALRAMATMRASSQYPFAVTLYVPNVPEGSVRIIDQSSNVEIASFPIYKVLFCARGHDGTAESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIPTPDSDVFTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKIKQGIEKKVVITVQQL... | endocytosis megakaryocyte development protein transport regulation of protein localization early endosome; Golgi apparatus; nucleus GTPase activator activity small GTPase binding Mus musculus Alternative splicing Endocytosis Endosome Golgi apparatus GTPase activation Phosphoprotein Protein transport Reference proteome ... |
adenosine metabolic process dephosphorylation lipid metabolic process lysosome organization positive regulation of adenosine receptor signaling pathway regulation of sensory perception of pain thiamine metabolic process | extracellular space; lysosome; plasma membrane; vesicle membrane | 5'-nucleotidase activity acid phosphatase activity lysophosphatidic acid phosphatase activity phosphatase activity protein tyrosine phosphatase activity thiamine phosphate phosphatase activity | Bos taurus | Disulfide bond Glycoprotein Hydrolase Lipid metabolism Reference proteome Secreted Signal | MRNAALLMTR | MRNAALLMTRATSLRLSLLLLLSFLPDLDGGVRAKELRFVTLVFRHGDRSPIETFPNDPIKESSWPQGFGQLTQLGMAQHYELGQYIRKRYENFLNESYKREQVHVRSTDIDRTLMSAMTNLAALFPPEGISIWNPSLPWQPIPVHTVPVSEDQLLYLPFRNCPRFQELQSETLISEEFQKRLQPYKDFIEVLPKLTGYHDQDLLGIWSKVYDPLFCEGVHNFTLPSWATEDTMTKLKEISELSLLSLYGIHKQKEKSRLQGGVLINEILNHMKSATQPSNRRKLIMYSAHDTTVSGLQMALDVYNGILPPYASCHMMEL... | adenosine metabolic process dephosphorylation lipid metabolic process lysosome organization positive regulation of adenosine receptor signaling pathway regulation of sensory perception of pain thiamine metabolic process extracellular space; lysosome; plasma membrane; vesicle membrane 5'-nucleotidase activity acid phosp... |
collagen fibril organization endothelial cell migration endothelial cell proliferation epithelial to mesenchymal transition heterochromatin organization negative regulation of DNA-templated transcription negative regulation of stem cell population maintenance negative regulation of transcription by RNA polymerase II pe... | basement membrane; chromatin; collagen-containing extracellular matrix; endoplasmic reticulum; extracellular space; membrane; nucleoplasm; nucleus | calcium ion binding copper ion binding oligosaccharide binding protein-lysine 6-oxidase activity | Bos taurus | Basement membrane Calcium Chromatin regulator Chromosome Copper Disulfide bond Endoplasmic reticulum Extracellular matrix Glycoprotein LTQ Metal-binding Nucleus Oxidoreductase Reference proteome Repeat Repressor Secreted Signal TPQ Transcription Transcription regulation | MERRGSSCLC | MERRGSSCLCRCLALLALLPTLSLAQYESWRHYPEYFQEPAPEYHRPEVPSDVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFTIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNVYCTGSEATLAACSSNGWGVTDCKHTEDVGVVCSEKRIPGFKFDNSLINSIENMNIQVEDIRIRAILSAFRKRTPVTEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGEKTYNTKVYKMFAARKKQRYWPYSMDCTGTEAHISSCKLGPQVSLDPVKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYK... | collagen fibril organization endothelial cell migration endothelial cell proliferation epithelial to mesenchymal transition heterochromatin organization negative regulation of DNA-templated transcription negative regulation of stem cell population maintenance negative regulation of transcription by RNA polymerase II pe... |
double-strand break repair via homologous recombination protein phosphorylation regulation of double-strand break repair via homologous recombination | centrosome; chromatin; cytoplasm; cytosol; nucleoplasm; nucleus; plasma membrane; protein phosphatase 4 complex | metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity | Bos taurus | Acetylation Cytoplasm Cytoskeleton Hydrolase Manganese Metal-binding Methylation Nucleus Protein phosphatase Reference proteome | MAEISDLDRQ | MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKKPVADYFL | double-strand break repair via homologous recombination protein phosphorylation regulation of double-strand break repair via homologous recombination centrosome; chromatin; cytoplasm; cytosol; nucleoplasm; nucleus; plasma membrane; protein phosphatase 4 complex metal ion binding myosin phosphatase activity protein seri... |
adaptive immune response endocytosis neuron projection morphogenesis podosome assembly positive regulation of axon extension positive regulation of dendritic spine morphogenesis postsynaptic actin cytoskeleton organization regulation of actin filament polymerization synapse assembly | anchoring junction; clathrin-coated vesicle membrane; cortical actin cytoskeleton; cytosol; dendrite; early endosome; Golgi membrane; lamellipodium; perikaryon; podosome; postsynaptic density; postsynaptic membrane; ruffle; site of polarized growth | actin filament binding | Bos taurus | Acetylation Actin-binding Adaptive immunity Cell junction Cell membrane Cell projection Coiled coil Cytoplasm Cytoplasmic vesicle Cytoskeleton Endocytosis Endosome Golgi apparatus Immunity Membrane Phosphoprotein Reference proteome SH3 domain Synapse Transport | MAVNLSRNGP | MAVNLSRNGPALLEAYQQVVNEKSSTDWALFTYEGNSNDIRVAGTGEGGLEEMVEELNSGKVMYAFCRVKDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMAGFLKGAHVTINARAEEDVEPECIMQKVARASGANYTFHKESSRFQDTGPQAPVGSVYQKTNAVSEIKRVGKDSFWAKAEKEEENRRLEEKRRAEEERQQLEQERRERELREAALREQRYQEQGGEAGLQRKYEQHEVLSRNREEQPAHPREIFKQKERAMSTTSISSPQPGKLKSPFLQKQLTQPDTPISRESPHATSRPRADLREEPVPSIPPC... | adaptive immune response endocytosis neuron projection morphogenesis podosome assembly positive regulation of axon extension positive regulation of dendritic spine morphogenesis postsynaptic actin cytoskeleton organization regulation of actin filament polymerization synapse assembly anchoring junction; clathrin-coated ... |
actin filament bundle organization autophagy centrosome cycle membrane tubulation neuron projection morphogenesis phagocytosis protein polymerization receptor-mediated endocytosis regulation of axon extension stress fiber assembly synaptic vesicle endocytosis vesicle scission | anchoring junction; cell junction; centriole; centrosome; clathrin-coated pit; clathrin-coated vesicle; cytoplasm; endosome; membrane; microtubule; midbody; neuron projection; phagocytic cup; phagocytic vesicle membrane; podosome; postsynaptic density; presynapse; recycling endosome; synapse; uropod | GTP binding GTPase activity microtubule binding phosphatidylinositol-4,5-bisphosphate binding protein self-association | Bos taurus | Acetylation Cell junction Cell projection Coated pit Cytoplasm Cytoplasmic vesicle Cytoskeleton Endocytosis Endosome GTP-binding Hydrolase Membrane Microtubule Motor protein Nucleotide-binding Phagocytosis Phosphoprotein Reference proteome Synapse Synaptosome | MGNRGMEELI | MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEYAEFLHCKSRKFTDFEEVRQEIEAETDRVTGTNKGISPVPINLRIYSPHVLNLTLIDLPGITKVPVGDQPQDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRTALAAERKFFLSHPAYRHIADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPD... | actin filament bundle organization autophagy centrosome cycle membrane tubulation neuron projection morphogenesis phagocytosis protein polymerization receptor-mediated endocytosis regulation of axon extension stress fiber assembly synaptic vesicle endocytosis vesicle scission anchoring junction; cell junction; centriol... |
adrenal chromaffin cell differentiation cell cycle negative regulation of cell population proliferation negative regulation of protein phosphorylation negative regulation of transcription by RNA polymerase II neuron differentiation noradrenergic neuron development norepinephrine biosynthetic process pancreatic A cell d... | nucleus; transcription repressor complex | chromatin DNA binding DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Bos taurus | Cell cycle Developmental protein Differentiation DNA-binding Metal-binding Neurogenesis Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger | MPRGFLVKRS | MPRGFLVKRSKKSTPVSYRIRGGEDGDRALLLLPGCGGARASPPAPGPGPVPGPLQPPPPTERAHAALAAALACAPGPPPPPPGLRAAHFGNPEAAHPAPLYSPTRPVSREHEKHKYFERSFNLGSPVSAESFPTPAALLVGGGGGGGGGGANGAGGGGTCSGDPLLFAPAELKMGTAFSAAAEAARGPGPGPPLPPAAALRPPGKRPSPPASAAAAAEPPAKVAKAPGSKKPKAIRKLHFEDEVTTSPVLGLKIKEGPVEAPRGRAGGAARPLGEFICQLCKEEYADPFALAQHKCSRIVRVEYRCPECAKVFSCPANL... | adrenal chromaffin cell differentiation cell cycle negative regulation of cell population proliferation negative regulation of protein phosphorylation negative regulation of transcription by RNA polymerase II neuron differentiation noradrenergic neuron development norepinephrine biosynthetic process pancreatic A cell d... |
potassium ion transmembrane transport potassium ion transport protein homooligomerization protein localization to plasma membrane | dendrite; neuronal cell body; neuronal cell body membrane; perikaryon; plasma membrane; voltage-gated potassium channel complex | delayed rectifier potassium channel activity protein heterodimerization activity transmembrane transporter binding | Mus musculus | Cell membrane Cell projection Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MAEKAPPGLN | MAEKAPPGLNRKTSRSTLSLPPEPVDIIRSKTCSRRVKINVGGLNHEVLWRTLDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETMREREGEEFDNTCCPEKRKKLWDLLEKPNSSVAAKILAIVSILFIVLSTIALSLNTLPELQENDEFGQPSDNRKLAHVEAVCIAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTG... | potassium ion transmembrane transport potassium ion transport protein homooligomerization protein localization to plasma membrane dendrite; neuronal cell body; neuronal cell body membrane; perikaryon; plasma membrane; voltage-gated potassium channel complex delayed rectifier potassium channel activity protein heterodim... |
embryonic cranial skeleton morphogenesis mRNA splicing, via spliceosome mRNA transport negative regulation of translation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay positive regulation of translation regulation of alternative mRNA splicing, via spliceosome regulation of nuclear-transcribed mRNA... | catalytic step 2 spliceosome; cytoplasm; exon-exon junction complex; nuclear speck; nucleolus; nucleus; U2-type catalytic step 1 spliceosome | ATP binding ATP hydrolysis activity mRNA binding poly(A) binding RNA helicase activity | Sus scrofa | Acetylation ATP-binding Cytoplasm Helicase Hydrolase Isopeptide bond mRNA processing mRNA splicing mRNA transport Nonsense-mediated mRNA decay Nucleotide-binding Nucleus Phosphoprotein Reference proteome RNA-binding rRNA processing Spliceosome Translation regulation Transport Ubl conjugation | MAATATMATS | MAATATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIM... | embryonic cranial skeleton morphogenesis mRNA splicing, via spliceosome mRNA transport negative regulation of translation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay positive regulation of translation regulation of alternative mRNA splicing, via spliceosome regulation of nuclear-transcribed mRNA... |
Gram-negative-bacterium-type cell outer membrane assembly lipopolysaccharide biosynthetic process O antigen biosynthetic process | Gram-negative-bacterium-type cell wall; membrane | glucosyltransferase activity glycogen (starch) synthase activity | Escherichia coli | Glycosyltransferase Lipopolysaccharide biosynthesis Membrane Transferase Transmembrane Transmembrane helix | MKIAYVVSSK | MKIAYVVSSKKKCGPNIVILNIVKELANKHEMEIFFLDESDDDVFECVNVKSTQIKKASDLKEHLKRFDIIHSSGIRPDALVVLCKVIYRVKCKIITTIHNYVFQDLYYSYGLVKSLIGGLLWCSIWLFFDKLVILSKNADNYYWFLPSAKKNIIYNGIDDNDCLQNKKCNYRKEFNIPDDGILAGSCANLTKRKGIDLVIQTLTKEHKIYYIVAGNGIEKHNLINLVKARKLHERVYFIDFLDEPESFMSQLDVFLMPSRSEGFGLTVLESTKLGIPVITSNIPIFMELFDQMCLTFDIKNPSTLIDVITYAKKNRLHL... | Gram-negative-bacterium-type cell outer membrane assembly lipopolysaccharide biosynthetic process O antigen biosynthetic process Gram-negative-bacterium-type cell wall; membrane glucosyltransferase activity glycogen (starch) synthase activity Escherichia coliGlycosyltransferase Lipopolysaccharide biosynthesis Membrane ... |
atrial cardiac muscle cell development cell differentiation digestive tract development embryonic heart tube development epithelial cell apoptotic process epithelial cell differentiation epithelial cell proliferation hypothalamus development negative regulation of apoptotic process negative regulation of epithelial cel... | chromatin; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Homo sapiens | Activator Developmental protein Disease variant DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MLLSPVTSTP | MLLSPVTSTPFSVKDILRLERERSCPAASPHPRVRKSPENFQYLRMDAEPRGSEVHNAGGGGGDRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQGHLAATLQGVRAW | atrial cardiac muscle cell development cell differentiation digestive tract development embryonic heart tube development epithelial cell apoptotic process epithelial cell differentiation epithelial cell proliferation hypothalamus development negative regulation of apoptotic process negative regulation of epithelial cel... |
cell adhesion fusion of sperm to egg plasma membrane involved in single fertilization single fertilization sperm-egg recognition | external side of plasma membrane; extracellular region; microvillus membrane; plasma membrane | signaling receptor activity signaling receptor binding | Homo sapiens | 3D-structure Alternative splicing Cell membrane Cell projection Disulfide bond Fertilization Glycoprotein GPI-anchor Lipoprotein Membrane Receptor Reference proteome Signal | MACWWPLLLE | MACWWPLLLELWTVMPTWAGDELLNICMNAKHHKRVPSPEDKLYEECIPWKDNACCTLTTSWEAHLDVSPLYNFSLFHCGLLMPGCRKHFIQAICFYECSPNLGPWIQPVGSLGWEVAPSGQGERVVNVPLCQEDCEEWWEDCRMSYTCKSNWRGGWDWSQGKNRCPKGAQCLPFSHYFPTPADLCEKTWSNSFKASPERRNSGRCLQKWFEPAQGNPNVAVARLFASSAPSWELSYTIMVCSLFLPFLS | cell adhesion fusion of sperm to egg plasma membrane involved in single fertilization single fertilization sperm-egg recognition external side of plasma membrane; extracellular region; microvillus membrane; plasma membrane signaling receptor activity signaling receptor binding Homo sapiens 3D-structure Alternative spli... |
BMP signaling pathway | cytosol; nucleus | protein kinase binding | Homo sapiens | Acetylation Alternative splicing Cytoplasm Nucleus Phosphoprotein Reference proteome | MAFSQVQCLD | MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKRILETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGTEFFTRSATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSHSVSLKGIPMEKE... | BMP signaling pathway cytosol; nucleus protein kinase binding Homo sapiens Acetylation Alternative splicing Cytoplasm Nucleus Phosphoprotein Reference proteome MAFSQVQCLD MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKRILETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASV... |
negative regulation of cytokine-mediated signaling pathway regulation of cell shape response to lipopolysaccharide Toll signaling pathway | cytoplasm; plasma membrane | ATP binding | Homo sapiens | ATP-binding Cell membrane Coiled coil Cytoplasm Lipoprotein Membrane Methylation Nucleotide-binding Palmitate Phosphoprotein Prenylation Reference proteome Repeat | MAESSLYRQR | MAESSLYRQRLEVIAEKRRLQEEIRAARREVEEEKLRVERLKRKSLRERWLMDGAAAVPEPSEDPTSKDPQSPEGQAQARIRNLEDSLFTLQSQLQLLQSASTGAQHKPSGRPSWRRQGHRPLSQSIVEAGSVGQTDLNKRASLPAGLVGTPPESPSEPREDVLGFLPGPRQVPGAAGDSSEANGPCPSPIPTPEQGLSQRAVPSEGRVGEAKGGGVVSVVWEGLRATEDCATGATGPELEAKVEEVVLEAIGDRKGAGSLELPAWVKEDRGIVEVVWEGVGGSDAEAMGEIGRVPEVVQTSSPRLQERLEAAASIEGED... | negative regulation of cytokine-mediated signaling pathway regulation of cell shape response to lipopolysaccharide Toll signaling pathway cytoplasm; plasma membrane ATP binding Homo sapiens ATP-binding Cell membrane Coiled coil Cytoplasm Lipoprotein Membrane Methylation Nucleotide-binding Palmitate Phosphoprotein Preny... |
male gonad development mRNA processing positive regulation of mRNA splicing, via spliceosome RNA splicing spermatogenesis | nucleolus; nucleoplasm; nucleus; spliceosomal complex | RNA binding | Homo sapiens | mRNA processing mRNA splicing Nucleus Reference proteome RNA-binding | MVEADHPGKL | MVEADHPGKLFIGGLNRETNEKMLKAVFGKHGPISEVLLIKDRTSKSRGFAFITFENPADAKNAAKDMNGKSLHGKAIKVEQAKKPSFQSGGRRRPPASSRNRSPSGSLRSARGSRGGTRGWLPSQEGHLDDGGYTPDLKMSYSRGLIPVKRGPSSRSGGPPPKKSAPSAVARSNSWMGSQGPMSQRRENYGVPPRRATISSWRNDRMSTRHDGYATNDGNHPSCQETRDYAPPSRGYAYRDNGHSNRDEHSSRGYRNHRSSRETRDYAPPSRGHAYRDYGHSRRDESYSRGYRNRRSSRETREYAPPSRGHGYRDYGHS... | male gonad development mRNA processing positive regulation of mRNA splicing, via spliceosome RNA splicing spermatogenesis nucleolus; nucleoplasm; nucleus; spliceosomal complex RNA binding Homo sapiens mRNA processing mRNA splicing Nucleus Reference proteome RNA-binding MVEADHPGKL MVEADHPGKLFIGGLNRETNEKMLKAVFGKHGPISEVLL... |
glycerol biosynthetic process glycerophospholipid metabolic process negative regulation of gluconeogenesis | cytoplasm | ADP phosphatase activity glycerol-1-phosphatase activity glycerol-3-phosphatase activity magnesium ion binding phosphoglycolate phosphatase activity protein tyrosine phosphatase activity | Homo sapiens | Carbohydrate metabolism Hydrolase Magnesium Metal-binding Protein phosphatase Reference proteome | MAAAEAGGDD | MAAAEAGGDDARCVRLSAERAQALLADVDTLLFDCDGVLWRGETAVPGAPEALRALRARGKRLGFITNNSSKTRAAYAEKLRRLGFGGPAGPGASLEVFGTAYCTALYLRQRLAGAPAPKAYVLGSPALAAELEAVGVASVGVGPEPLQGEGPGDWLHAPLEPDVRAVVVGFDPHFSYMKLTKALRYLQQPGCLLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPERTVMVGDRLDTDILLGATCGLKTILTLTGVSTLGDVKNNQESDCVSKKKMVPDFYVDSIADLLPALQ... | glycerol biosynthetic process glycerophospholipid metabolic process negative regulation of gluconeogenesis cytoplasm ADP phosphatase activity glycerol-1-phosphatase activity glycerol-3-phosphatase activity magnesium ion binding phosphoglycolate phosphatase activity protein tyrosine phosphatase activity Homo sapiens Car... |
negative regulation of Wnt signaling pathway positive regulation of protein oxidation positive regulation of protein-containing complex assembly proteolysis Wnt signaling pathway | membrane; organelle membrane; plasma membrane | metal ion binding metalloendopeptidase activity Wnt-protein binding | Homo sapiens | Cell membrane Glycoprotein Hydrolase Membrane Metal-binding Metalloprotease Protease Reference proteome Signal Transmembrane Transmembrane helix Wnt signaling pathway | MHAALAGPLL | MHAALAGPLLAALLATARARPQPPDGGQCRPPGSQRDLNSFLWTIRRDPPAYLFGTIHVPYTRVWDFIPDNSKAAFQASTRVYFELDLTDPYTISALASCQLLPHGENLQDVLPHELYWRLKRHLDYVKLMMPSWMTPAQRGKGLYADYLFNAIAGNWERKRPVWVMLMVNSLTERDVRFRGVPVLDLYLAQQAEKMKKTTGAVEQVEEQCHPLNNGLNFSQVLFALNQTLLQQESVRAGSLQASYTTEDLIKHYNCGDLSAVIFNHDTSQLPNFINTTLPPHEQVTAQEIDSYFRQELIYKRNERMGKRVMALLRENED... | negative regulation of Wnt signaling pathway positive regulation of protein oxidation positive regulation of protein-containing complex assembly proteolysis Wnt signaling pathway membrane; organelle membrane; plasma membrane metal ion binding metalloendopeptidase activity Wnt-protein binding Homo sapiens Cell membrane ... |
negative regulation of anion channel activity positive regulation of cell migration positive regulation of protein targeting to membrane | cell junction; plasma membrane | transmembrane transporter binding | Homo sapiens | Alternative splicing Cell membrane Membrane Reference proteome Transport | MATIAAAAFE | MATIAAAAFEALMDGVTCWDVPRGPIPSELLLIGEAAFPVMVNDKGQVLIAASSYGRGRLVVVSHEGYLSHTGLAPFLLNAVSWLCPCPGAPVGVHPSLAPLVNILQDAGLEAQVKPEPGEPLGVYCINAYNDTLTATLIQFVKHGGGLLIGGQAWYWASQHGPDKVLSRFPGNKVTSVAGVYFTDTYGDRDRFKVSKKVPKIPLHVRYGEDVRQDQQQLLEGISELDIRTGGVPSQLLVHGALAFPLGLDASLNCFLAAAHYGRGRVVLAAHECLLCAPKMGPFLLNAVRWLARGQTGKVGVNTNLKDLCPLLSEHGLQ... | negative regulation of anion channel activity positive regulation of cell migration positive regulation of protein targeting to membrane cell junction; plasma membrane transmembrane transporter binding Homo sapiens Alternative splicing Cell membrane Membrane Reference proteome Transport MATIAAAAFE MATIAAAAFEALMDGVTCWDV... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.