"""Geometry helpers: signed distance fields, point sampling, marching cubes.""" import numpy as np from scipy import ndimage as ndi def sdf_from_mask(mask, spacing=(1.0, 1.0, 1.0)): """Signed distance field in mm. Negative inside the mask, positive outside, 0 on surface. mask: bool/0-1 array [x,y,z]; spacing: voxel size per axis (mm).""" mask = mask.astype(bool) spacing = tuple(float(s) for s in spacing) if not mask.any(): # no structure -> large positive distance everywhere return np.full(mask.shape, 10.0, dtype=np.float32) if mask.all(): return np.full(mask.shape, -10.0, dtype=np.float32) out = ndi.distance_transform_edt(~mask, sampling=spacing) inn = ndi.distance_transform_edt(mask, sampling=spacing) sdf = out - inn return sdf.astype(np.float32) def normals_from_sdf(sdf, spacing=(1.0, 1.0, 1.0)): """Unit gradient of the SDF (surface normals), [x,y,z,3].""" gx, gy, gz = np.gradient(sdf, spacing[0], spacing[1], spacing[2]) g = np.stack([gx, gy, gz], axis=-1) n = np.linalg.norm(g, axis=-1, keepdims=True) n = np.clip(n, 1e-6, None) return (g / n).astype(np.float32) def sample_surface_and_random(mask, spacing, n_points, near_ratio=0.6, sigma_mm=0.6, rng=None): """Return query coordinates in *voxel* units within a ROI. A fraction near the surface (jittered surface voxels) + the rest uniform random.""" rng = rng or np.random.default_rng() shape = np.array(mask.shape) n_near = int(n_points * near_ratio) n_rand = n_points - n_near # surface voxels: boundary between mask and background mask = mask.astype(bool) if mask.any(): eroded = ndi.binary_erosion(mask) surf = mask & ~eroded coords = np.argwhere(surf) else: coords = np.zeros((0, 3)) if len(coords) > 0: idx = rng.integers(0, len(coords), size=n_near) near = coords[idx].astype(np.float32) sigma_vox = np.array(sigma_mm) / np.array(spacing) near = near + rng.normal(0, 1, near.shape) * sigma_vox[None, :] else: near = rng.random((n_near, 3)) * (shape - 1)[None, :] rand = rng.random((n_rand, 3)) * (shape - 1)[None, :] pts = np.concatenate([near, rand], axis=0).astype(np.float32) pts = np.clip(pts, 0, (shape - 1)[None, :]) return pts def trilinear_sample(vol, pts): """Sample a scalar/vector volume at fractional voxel coords pts [N,3] -> [N,(C)]. vol: [x,y,z] or [x,y,z,C]. Pure-numpy trilinear interpolation.""" pts = np.asarray(pts, dtype=np.float32) x, y, z = pts[:, 0], pts[:, 1], pts[:, 2] sx, sy, sz = vol.shape[:3] x0 = np.clip(np.floor(x).astype(int), 0, sx - 1); x1 = np.clip(x0 + 1, 0, sx - 1) y0 = np.clip(np.floor(y).astype(int), 0, sy - 1); y1 = np.clip(y0 + 1, 0, sy - 1) z0 = np.clip(np.floor(z).astype(int), 0, sz - 1); z1 = np.clip(z0 + 1, 0, sz - 1) xd = (x - x0)[:, None] if vol.ndim == 4 else (x - x0) yd = (y - y0)[:, None] if vol.ndim == 4 else (y - y0) zd = (z - z0)[:, None] if vol.ndim == 4 else (z - z0) def g(a, b, c): return vol[a, b, c] c00 = g(x0, y0, z0) * (1 - xd) + g(x1, y0, z0) * xd c01 = g(x0, y0, z1) * (1 - xd) + g(x1, y0, z1) * xd c10 = g(x0, y1, z0) * (1 - xd) + g(x1, y1, z0) * xd c11 = g(x0, y1, z1) * (1 - xd) + g(x1, y1, z1) * xd c0 = c00 * (1 - yd) + c10 * yd c1 = c01 * (1 - yd) + c11 * yd return c0 * (1 - zd) + c1 * zd def canal_centerline(mask): """3D skeleton (centerline) of a binary canal mask -> bool array [x,y,z].""" mask = mask.astype(bool) if not mask.any(): return np.zeros_like(mask) try: from skimage.morphology import skeletonize return skeletonize(mask).astype(bool) except Exception: try: from skimage.morphology import skeletonize_3d return skeletonize_3d(mask).astype(bool) except Exception: return np.zeros_like(mask) def marching_cubes_to_mesh(sdf_grid, level=0.0, spacing=(1.0, 1.0, 1.0), origin=(0.0, 0.0, 0.0), pad=False, watertight=False): """SDF grid -> trimesh.Trimesh in world (mm) coordinates. Returns None if empty. pad : pad the grid with a positive border so the zero-level set never touches the volume boundary -> MC produces a closed surface. watertight : keep the largest connected component and fill holes. """ import trimesh from skimage import measure if pad: bigval = float(abs(sdf_grid).max() + max(spacing)) sdf_grid = np.pad(sdf_grid, 1, mode="constant", constant_values=bigval) origin = np.array(origin) - np.array(spacing) # shift to keep world coords if sdf_grid.min() > level or sdf_grid.max() < level: return None try: verts, faces, normals, _ = measure.marching_cubes( sdf_grid, level=level, spacing=tuple(float(s) for s in spacing)) except Exception: return None verts = verts + np.array(origin)[None, :] mesh = trimesh.Trimesh(vertices=verts, faces=faces, vertex_normals=normals, process=True) if watertight: try: comps = mesh.split(only_watertight=False) if len(comps) > 1: mesh = max(comps, key=lambda m: len(m.faces)) mesh.fill_holes() mesh.remove_degenerate_faces() mesh.remove_duplicate_faces() mesh.fix_normals() except Exception: pass return mesh