"""Stage 0 preprocessing: per case, produce a compact processed bundle: - image (normalized, [x,y,z] float32) at working spacing - sem (0 bg / 1 tooth-solid / 2 canal) for Stage-1 segmentation - inst (tooth instance id 0..28, from tooth_solid) for Stage-2 ROI cropping - cinst (canal instance id 0..28) - cleaning report (json) for the QC before/after table Run: python -m toothcanal.preprocess --config configs/default.yaml """ import os, argparse import numpy as np from tqdm import tqdm from .utils import (load_config, ensure_dir, load_nii, resample_to_spacing, read_json, write_json) from .cleaning import build_instances def normalize_image(img, clip): img = np.clip(img, clip[0], clip[1]).astype(np.float32) lo, hi = float(img.min()), float(img.max()) if hi - lo < 1e-5: return np.zeros_like(img) return (img - lo) / (hi - lo) def _fit_to_shape(arr, shape): """Crop or zero-pad a label array to an exact target shape.""" out = np.zeros(shape, dtype=arr.dtype) s = [min(shape[k], arr.shape[k]) for k in range(3)] out[:s[0], :s[1], :s[2]] = arr[:s[0], :s[1], :s[2]] return out def _resample_label_to_reference(lab, lmeta, ref_img, ref_meta): """Resample a label volume onto the reference image's exact voxel grid using SimpleITK (nearest neighbor), so label and image align even when the annotation was made at a different resolution.""" import SimpleITK as sitk lab_t = np.transpose(lab, (2, 1, 0)) li = sitk.GetImageFromArray(lab_t) li.SetSpacing(tuple(float(s) for s in lmeta["spacing"])) li.SetOrigin(tuple(float(o) for o in lmeta["origin"])) li.SetDirection(tuple(float(d) for d in lmeta["direction"])) ref_t = np.transpose(ref_img, (2, 1, 0)) ri = sitk.GetImageFromArray(ref_t) ri.SetSpacing(tuple(float(s) for s in ref_meta["spacing"])) ri.SetOrigin(tuple(float(o) for o in ref_meta["origin"])) ri.SetDirection(tuple(float(d) for d in ref_meta["direction"])) out = sitk.Resample(li, ri, sitk.Transform(), sitk.sitkNearestNeighbor, 0, li.GetPixelID()) o = sitk.GetArrayFromImage(out) return np.transpose(o, (2, 1, 0)).astype(np.int16) def process_case(cid, info, cfg): from .assemble import assemble_label pp = cfg["preprocess"] img, imeta = load_nii(info["image"]) lab, lmeta = load_nii(info["label"]) lab = np.rint(lab).astype(np.int16) # merge supplementary tooth labels for canal-only cases (e.g. 21-30) lab, status = assemble_label(lab, info.get("num", -1), cfg) if status == "canal_only": print(f"[preprocess] SKIP {cid}: only canal labels, no tooth labels found " f"(drop tooth nii into paths.extra_tooth_dir).") return None # If label grid differs from image grid (different annotation resolution), # first put the label onto the image's exact grid, THEN resample both together. if lab.shape != img.shape: lab = _resample_label_to_reference(lab, lmeta, img, imeta) # resample both to working spacing (image linear, label nearest) img, imeta2 = resample_to_spacing(img, imeta, pp["spacing"], is_label=False) lab, _ = resample_to_spacing(lab, imeta, pp["spacing"], is_label=True) lab = np.rint(lab).astype(np.int16) imeta = imeta2 # final safety: crop/pad label to image shape so indexing never mismatches if lab.shape != img.shape: lab = _fit_to_shape(lab, img.shape) img = normalize_image(img, pp["clip_hu"]) instances, report = build_instances(lab, cfg) sem = np.zeros(img.shape, dtype=np.uint8) # 1 tooth-solid, 2 canal, 3 descriptor-core inst = np.zeros(img.shape, dtype=np.uint8) # tooth instance id cinst = np.zeros(img.shape, dtype=np.uint8) # canal instance id desc = np.zeros(img.shape, dtype=np.uint8) # 1 = eroded tooth-core descriptor from scipy import ndimage as _ndi erode_iter = int(cfg["preprocess"].get("descriptor_erode_iter", 3)) for i, d in instances.items(): sem[d["tooth_solid"]] = 1 inst[d["tooth_solid"]] = i sem[d["canal"]] = 2 cinst[d["canal"]] = i # descriptor = tooth body eroded so neighboring teeth separate into cores core = _ndi.binary_erosion(d["tooth_solid"], iterations=erode_iter) if not core.any(): # tiny tooth: keep a seed voxel core = d["tooth_solid"] desc[core] = i # store instance id in the core map # Stage-1 semantic target: 0 bg / 1 tooth / 2 canal / 3 descriptor-core sem[desc > 0] = 3 out_dir = ensure_dir(cfg["paths"]["proc_dir"]) np.savez_compressed( os.path.join(out_dir, f"{cid}.npz"), image=img.astype(np.float32), sem=sem, inst=inst, cinst=cinst, desc=desc, spacing=np.array(imeta["spacing"], dtype=np.float32), origin=np.array(imeta["origin"], dtype=np.float32), n_instances=len(instances), ) return dict(case=cid, n_instances=len(instances), cleaning=report, status=status, shape=list(img.shape)) def main(): ap = argparse.ArgumentParser() ap.add_argument("--config", default="configs/default.yaml") ap.add_argument("--limit", type=int, default=0, help="process only first N (debug)") ap.add_argument("--force", action="store_true", help="reprocess cases even if their .npz already exists") args = ap.parse_args() cfg = load_config(args.config) manifest = read_json(os.path.join(cfg["paths"]["raw_dir"], "manifest.json")) items = list(manifest.items()) if args.limit: items = items[:args.limit] ensure_dir(cfg["paths"]["proc_dir"]) if not args.force: before = len(items) items = [(cid, info) for cid, info in items if not os.path.exists(os.path.join(cfg["paths"]["proc_dir"], f"{cid}.npz"))] skipped = before - len(items) if skipped: print(f"[preprocess] skipping {skipped} already-processed case(s); " f"will process {len(items)}.") summary = [] for cid, info in tqdm(items, desc="preprocess"): try: r = process_case(cid, info, cfg) if r is not None: summary.append(r) except Exception as e: print(f"[preprocess] FAILED {cid}: {e}") write_json(summary, os.path.join(cfg["paths"]["proc_dir"], "preprocess_report.json")) # ---- aggregate report (handles both 'offset' per-instance and 'geometric' summary) ---- nb = na = vb = va = specks = 0 reassigned = orphaned = ncomp = geo_cases = 0 for s in summary: for c in s["cleaning"]: if "pairing" in c: # geometric re-pairing summary reassigned += c.get("voxels_reassigned", 0) orphaned += c.get("voxels_orphaned", 0) ncomp += c.get("n_components", 0) geo_cases += 1 else: # legacy offset per-instance cleaning nb += c.get("n_components_before", 0); na += c.get("n_components_after", 0) vb += c.get("voxels_before", 0); va += c.get("voxels_after", 0) specks += c.get("removed_specks", 0) if geo_cases: print("\n========== canal<->tooth geometric re-pairing ==========") print(f"cases re-paired: {geo_cases} | canal components: {ncomp}") print(f"voxels re-assigned to correct tooth: {reassigned} | orphaned/dropped: {orphaned}") print("========================================================") if vb: print("\n========== canal cleaning (before / after) ==========") print(f"components: {nb} -> {na} (removed {specks} specks)") print(f"voxels retained: {100.0 * va / vb:.2f}% (lost {100.0 * (vb - va) / vb:.2f}%)") print("=====================================================") if __name__ == "__main__": main()