| COc1cc2c(N3CCN(C(=O)Nc4ccc(OC(C)C)cc4)CC3)ncnc2cc1OCCCN1CCCCC1,CHEMBL124660,6.7 |
| Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)cc1Nc1nccc(-c2cccnc2)n1,CHEMBL941,6.8 |
| Cc1cccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)cc2)c1,CHEMBL196363,8.7 |
| Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4n[nH]c(N)c34)cc2)c1,CHEMBL223360,8.1 |
| Cc1cccc(NC(=O)Nc2ccc(-c3cncc4c3c(N)nn4C)cc2)c1,CHEMBL404367,7.6 |
| COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1,CHEMBL261849,7.4 |
| Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1S(N)(=O)=O,CHEMBL477772,7.7 |
| CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1,CHEMBL1336,6.8 |
| COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(N)=O)s3)c2cc1OC,CHEMBL514499,6.3 |
| CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1,CHEMBL522892,7.4 |
| CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1,CHEMBL574738,7.3 |
| Nc1nc(Nc2ccc(S(N)(=O)=O)cc2)nn1C(=O)c1c(F)cccc1F,CHEMBL191003,5.9 |
| Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1,CHEMBL101253,6.0 |
| NCCn1cc(-c2cc(-c3cc4ccccc4s3)c3n[nH]cc3c2)c2nc(N)ncc21,CHEMBL590109,5.6 |
| O=C(Cc1ccccc1)Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCOCC4)c3)n2)c1,CHEMBL1090360,6.0 |
| CN1CCN(c2ccc(-c3cnc4c(c3)N(Cc3cc(Cl)ccc3C(F)(F)F)CCN4)cn2)CC1,CHEMBL1164180,6.5 |
| CN1CCN(c2ccc(-c3cnc4c(c3)N(Cc3c(F)ccc(F)c3Cl)CCN4)cn2)CC1,CHEMBL1164265,6.4 |
| Nc1ncnc2c1c(-c1cnc3[nH]ccc3c1)nn2C1CCCC1,CHEMBL1081312,6.4 |
| COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCCC1,CHEMBL491473,7.1 |
| COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1,CHEMBL509032,6.4 |
| CCCn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1,CHEMBL1993941,8.5 |
| Cc1cc(N2CCOCC2)cc2[nH]c(-c3c(NCC(O)c4cccc(Cl)c4)cc[nH]c3=O)nc12,CHEMBL2005886,7.6 |
| NC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1ccccc1C(F)(F)F,CHEMBL481491,5.7 |
| NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccc[nH]2)C(=O)N3)c1)Cc1ccccc1,CHEMBL1980407,6.2 |
| Cc1cccc(NC(=O)Nc2ccc(-c3csc4nc(N)nc(N)c34)cc2)c1,CHEMBL1973145,8.5 |
| NC1CCC(Nc2nccc(-c3c[nH]c4ncccc34)n2)CC1,CHEMBL1966628,7.0 |
| Cc1cccc(NC(=O)Nc2ccc(-c3cccc(C(N)=O)c3)cc2)c1,CHEMBL1971141,6.4 |
| COc1ccc(-c2ccc(NC(=O)Nc3ccc(OC(F)(F)F)cc3)cc2)c2c(N)noc12,CHEMBL1973178,8.3 |
| O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3c[nH]nc3c2)n1,CHEMBL244378,6.5 |
| Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4n[nH]c(N)c34)c(F)c2)c1,CHEMBL1988778,8.5 |
| OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1,CHEMBL1986943,6.7 |
| CCn1c(C)c(-c2ccnc(Nc3cccc(OC)c3)n2)sc1=O,CHEMBL1986263,6.4 |
| O=C(Nc1cnccn1)Nc1ccnc2c(F)cccc12,CHEMBL1975647,6.0 |
| CN1c2ccc(N)cc2C(c2ccccc2)c2cc(N)ccc21,CHEMBL1991734,5.9 |
| CNC(=O)C(C)n1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5ccc(C)cc5)cc4)csc23)cn1,CHEMBL1970142,8.0 |
| Nc1[nH]nc2ncc(Br)cc12,CHEMBL2002105,4.5 |
| NS(=O)(=O)c1cccc(Nc2ncc3ccn(-c4ccccc4)c3n2)c1,CHEMBL1988163,5.6 |
| Cc1cc(O)ccc1-n1c2cc(Cl)ccc2c(=O)c2c(N)nc(N)nc21,CHEMBL1995592,6.8 |
| CCOC(=O)Cc1nc2c3cc(Br)ccc3nc(=O)n2[nH]1,CHEMBL1974480,6.0 |
| Nc1ncnc2c1C(=O)Nc1ccccc1N2,CHEMBL1980671,5.6 |
| CCc1nc2c(c3cc(OC)c(OC)cc13)C(=O)NC2=O,CHEMBL2003524,5.7 |
| Cn1c(=O)n(-c2ccc(C(C)(C)C#N)cc2)c2c3cc(-c4cnc5ccccc5c4)ccc3ncc21,CHEMBL1879463,6.5 |
| Cc1cccc(NC(=O)Nc2ccc(-c3ccc4nccnc4c3N)cc2)c1,CHEMBL507936,8.2 |
| CCN1CCN(c2ccc(Nc3ncc(Cl)c(Nc4ccc5n[nH]cc5c4)n3)cc2)CC1,CHEMBL1967998,8.2 |
| Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCNS(C)(=O)=O)cnc(N)c34)cc2)c1,CHEMBL1994321,8.0 |
| Cn1cc(-c2cc3nc(Br)cnc3[nH]2)c2cc(C#N)ccc21,CHEMBL1978562,5.7 |
| O=C1NCCc2[nH]c(-c3ccnc(C=Cc4ccccc4)c3)cc21,CHEMBL1997129,6.2 |
| NC(=O)c1cc(Cl)cc2[nH]c(-c3ccc(C4CCCNC4)cc3F)nc12,CHEMBL1984788,6.4 |
| Cc1cccc(NC(=O)Cc2ccc(-c3cccc4n[nH]c(N)c34)cc2)c1,CHEMBL1964307,7.9 |
| Cc1ccnc2[nH]c3cc(C(C)C)ccc3c(=O)c12,CHEMBL1989471,6.1 |
| COc1ccc(CN(C)C)cc1Nc1nccc(-c2c(-c3cccc(NC(=O)Cc4ccccc4)c3)nc3sccn23)n1,CHEMBL1966842,6.3 |
| CC(O)Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1,CHEMBL2002165,8.5 |
| Nc1ncnc2scc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12,CHEMBL1998585,7.7 |
| Nc1[nH]nc2cccc(-c3ccc(NC(=O)Nc4cccc(Cl)c4)c(F)c3)c12,CHEMBL2000652,8.7 |
| CCN1CCN(c2ccc(Nc3ncc(C#N)c(Nc4ccc5n[nH]cc5c4)n3)cc2)CC1,CHEMBL1973516,7.75 |
| COCOc1cccc(OCOC)c1-c1ccc(NS(C)(=O)=O)cc1C(=O)OC,CHEMBL2004025,6.2 |
| Cc1ccc(-c2cc3c(NCCN)ccc(C(N)=O)c3[nH]2)cc1,CHEMBL1996048,6.1 |
| Cc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C(C)C(=O)N(C)C)c5)cnc(N)c34)cc2)cc1,CHEMBL2001485,7.0 |
| Nc1[nH]nc2cccc(-c3ccc(F)cc3)c12,CHEMBL1971519,5.1 |
| CNC(=O)COc1ccc(Nc2nc(Nc3ccc(C)c(S(N)(=O)=O)c3)ncc2F)cc1,CHEMBL1978099,6.6 |
| COC(=O)c1c(-c2ccc(NC(=O)Nc3ccccc3)cc2)c2c(N)ncnn2c1C,CHEMBL1977041,7.4 |
| O=C1CCCN1Cc1ccc2c(c1)[nH]c(=O)c1cccn12,CHEMBL539474,5.7 |
| Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5ccc(OC(F)F)cc5)cc4)csc23)cn1,CHEMBL1988387,7.9 |
| Cc1[nH]nc2cccc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12,CHEMBL1970074,7.5 |
| O=c1cc(-c2ccncc2)[nH]c(NC2CCCCC2)n1,CHEMBL1958401,5.6 |
| CCN(CC)CCOc1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1,CHEMBL1984044,6.3 |
| O=C(Nc1cccc(C(F)(F)F)n1)Nc1ccnc2c(F)cccc12,CHEMBL1966816,5.9 |
| CC(=O)N1CCN(C2CCC(n3nc(-c4ccc(NC(=O)c5cc6ccccc6n5C)cc4)c4c(N)ncnc43)CC2)CC1,CHEMBL1972584,6.2 |
| CCCOn1c2ccc(Cl)cc2c(=O)c2c(C)nn(C)c21,CHEMBL207253,6.2 |
| Cc1c(-c2cccc(OCc3ccccc3)c2)c2c(N)ncnc2n1C1CC(CN2CCCC2)C1,CHEMBL1968791,6.9 |
| Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN5CCCC5)cnc(N)c34)cc2)c1,CHEMBL1973211,8.0 |
| Cc1c(-c2cccc(OCc3ccccc3)c2)c2c(N)ncnc2n1C1CCC(N2CCCC2)CC1,CHEMBL2007151,6.3 |
| CC(C)c1cc(=O)[nH]c2[nH][nH]c(=O)c12,CHEMBL1999120,5.0 |
| CCN(CC)CCCNC(=O)c1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12,CHEMBL1999414,8.6 |
| CCOc1nc(C(=O)NCc2ccccc2S(N)(=O)=O)cc(N)c1Cl,CHEMBL2006581,5.6 |
| Cc1ccc(F)c(NC(=O)Nc2ccc(-c3coc4c(C#CCN5CCOCC5)cnc(N)c34)cc2)c1,CHEMBL1983640,8.3 |
| Cc1cc(C)cc(NC(=O)Nc2ccc3c(c2)CCc2sc4ncnc(N)c4c2-3)c1,CHEMBL1964687,7.7 |
| CCOc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)cc1,CHEMBL1974254,8.6 |
| c1ccc(CNc2nc(Nc3cc(C4CC4)n[nH]3)c3sccc3n2)cc1,CHEMBL1997924,7.4 |
| Cc1ccc(NC(=O)Nc2ccc(-c3coc4ncnc(N)c34)cc2)cc1,CHEMBL2005828,6.3 |
| NC(=O)c1sc2c(Br)ccc(Cl)c2c1N,CHEMBL1998611,5.7 |
| CNC(=O)C=Cc1cnc(N)c2c(-c3cc(F)c4[nH]c(C)cc4c3)csc12,CHEMBL2006778,8.4 |
| O=C(Nc1cnc2[nH]cc(-c3ccccc3)c2c1)c1c(F)cccc1F,CHEMBL1996979,6.5 |
| NC(=O)c1cccc2[nH]c(-c3ccc(C4CCCNC4)cc3F)nc12,CHEMBL1997025,6.1 |
| CNC(=O)c1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)csc12,CHEMBL1982476,8.8 |
| Cc1cc(Nc2nc(Cl)cc(NCc3ccccc3)n2)[nH]n1,CHEMBL2005449,5.9 |
| Nc1[nH]nc2cc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)ccc12,CHEMBL1997623,6.9 |
| Nc1nc2ncc(-c3ccccc3)cn2n1,CHEMBL2002480,4.0 |
| Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCCCCCCCCN)cnc(N)c34)cc2)c1,CHEMBL1978166,7.4 |
| Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)c1,CHEMBL1967116,8.8 |
| O=C1Nc2ccccc2C1=Cc1ccc[nH]1,CHEMBL1996176,6.35 |
| COc1cc(Nc2ncnc(N3CCCc4cc(C)ccc43)n2)cc(OC)c1OC,CHEMBL1992125,5.7 |
| Cc1cc(NC(=O)Nc2ccc(-c3c(F)ccc4n[nH]c(N)c34)cc2)ccc1F,CHEMBL1993996,8.9 |
| Nc1ncnc2sc(Br)c(-c3ccc(NC(=O)Cc4cccc(Cl)c4)cc3)c12,CHEMBL1980896,7.6 |
| CC(C)(C)c1ccc2nc(-c3n[nH]c4ccccc34)[nH]c2c1,CHEMBL1970104,6.5 |
| CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4,CHEMBL1980995,8.1 |
| COc1cc2cnc3c(c2cc1OC)C(=O)NC3=O,CHEMBL1982506,5.8 |
| CCN(CC)CCNC(=O)C=Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12,CHEMBL2004716,7.8 |
| Nc1nnc2cncc(Cl)n12,CHEMBL1968130,4.1 |
| CNC(=O)C=Cc1cnc(N)c2c(-c3ccc4c(c3)OCO4)csc12,CHEMBL1993243,7.5 |
| Nc1ncnc2c1c(-c1cccc(OCc3ccccc3)c1)cn2C1CC(CN2CCCC2)C1,CHEMBL1988370,6.0 |
| Cc1cccc(NC(=O)Nc2ccc(-c3cnc4c(-c5cnn(C)c5)cnn4c3N)cc2)c1,CHEMBL508928,7.5 |
| COc1cccc(-c2cc3c(=O)[nH]c4ccccc4n3c2)c1,CHEMBL1991356,5.6 |
| O=c1nc[nH]c2c(Cl)cccc12,CHEMBL1949855,4.4 |
| CN(C)CC(O)COc1ccc(Nc2nccc(Nc3cc(Cl)ccc3Cl)n2)cc1,CHEMBL101311,6.0 |
| Cc1ccc(F)c(NC(=O)Nc2ccc(-c3nsc4ncnc(N)c34)cc2)c1,CHEMBL262433,5.9 |
| Nc1[nH]nc2cccc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12,CHEMBL373798,9.2 |
| Cc1ccc(-c2nn(C(C)(C)C)c3ncnc(N)c23)cc1,CHEMBL306380,6.2 |
| Cc1cc(=O)n2ccc(CN(C)C)c(O)c2n1,CHEMBL1988581,6.9 |
| Cc1cc(C)cc(NC(=O)Nc2ccc(-c3cccc4snc(N)c34)cc2)c1,CHEMBL1976328,5.9 |
| Cc1cccc(NC(=O)Nc2ccc(-c3csc4ccnc(N)c34)cc2)c1,CHEMBL394619,8.2 |
| CCN(C(C)=O)c1ccc(Nc2nc(NC3CC3)c3[nH]cnc3n2)cc1,CHEMBL2006564,6.9 |
| COc1ccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)cc1OC,CHEMBL1964399,5.6 |
| Nc1ncnc2c1N=C(c1ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc1)CCN2,CHEMBL411903,6.2 |
| Nc1[nH]nc2c(-c3ccccc3)cccc12,CHEMBL1991008,4.2 |
| Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN)cnc(N)c34)cc2)c1,CHEMBL1965988,8.3 |
| CCOc1nc(C(=O)NCc2cccnc2)cc(N)c1C#N,CHEMBL209534,5.9 |
| CC(=O)c1cccc(-c2ccc3nccn3n2)c1,CHEMBL1994159,4.2 |
| COc1cc(C=C2SC(=Nc3ccccc3)NC2=O)ccc1O,CHEMBL1970522,5.8 |
| Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cncc4c3c(N)nn4C)cc2)c1,CHEMBL402846,9.0 |
| Cn1nc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)cncc21,CHEMBL1964692,6.5 |
| O=C(Cc1ccccc1)Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3ccccc3Cl)n2)c1,CHEMBL1995428,6.2 |
| Nc1[nH]nc2cccc(-c3ccc(NC(=O)Nc4ccccc4)cc3)c12,CHEMBL219722,8.2 |
| Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1,CHEMBL482967,6.2 |
| CNC(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCOCC3)cc2OC)ncc1Cl,CHEMBL458997,5.8 |
| NC(=O)c1cccc(-c2cnc3[nH]cc(-c4ccccc4)c3c2)c1,CHEMBL1982957,6.4 |
| O=C1c2ccccc2-c2n[nH]c3cccc1c23,CHEMBL1725279,6.9 |
| c1ccc(CNc2cc(-c3c[nH]c4ncccc34)ncn2)cc1,CHEMBL2002346,6.7 |
| CCOc1nc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cc(N)c1C#N,CHEMBL424872,6.2 |
| Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#Cc5cccnc5)cnc(N)c34)cc2)c1,CHEMBL1971947,7.8 |
| Cc1ccc(F)c(NC(=O)Nc2ccc(-c3c(F)ccc4n[nH]c(N)c34)cc2)c1,CHEMBL1996255,8.9 |
| CCN(CC)CCOc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1,CHEMBL49120,9.2 |
| CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12,CHEMBL1983111,7.2 |
| Nc1[nH]nc2nnc(-c3ccccc3)c(-c3ccccc3)c12,CHEMBL260135,5.6 |
| CCC(=O)Nc1ccc(C(=O)N2CCNCC2)c(O)c1,CHEMBL1988141,6.6 |
| Nc1c(-c2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)cnc2c(-c3ccc4c(c3)OCO4)cnn12,CHEMBL1977134,7.2 |
| Nc1ccc(-c2csc3c(C=Cc4nc5ccccc5[nH]4)cnc(N)c23)cc1,CHEMBL1988300,7.3 |
| Nc1ncnc2scc(-c3ccccc3)c12,CHEMBL1975212,5.7 |
| O=c1[nH][nH]c2ccc(Br)cc12,CHEMBL2001613,4.4 |
| NC(=O)c1cc2c(-c3ccc(Nc4nc5ccccc5o4)cc3)cnc(N)c2s1,CHEMBL1993904,6.1 |
| Cc1cccc(-c2cccc3onc(N)c23)c1,CHEMBL1980376,4.8 |
| Nc1[nH]nc2cccc(-c3ccc(NC(=O)Nc4cc(CO)ccc4F)cc3)c12,CHEMBL1985311,8.3 |
| Nc1ncnc2c1c(-c1cccc(OCc3ccccc3)c1)cn2C1CCC(N2CCCC2)CC1,CHEMBL1965910,5.9 |
| Cc1cccc(NC(=O)Nc2ccc(-c3coc4ncnc(N)c34)cc2)c1,CHEMBL1983963,8.7 |
| COc1ccc(C(=O)Nc2cnc3[nH]cc(-c4ccccc4)c3c2)cc1,CHEMBL1997764,5.7 |
| N#Cc1ncc2nc1OCCCCCOc1cc(CCCO)c(Cl)cc1NC(=O)N2,CHEMBL223367,7.7 |
| O=c1nc2ccc(Cl)cc2c2nc[nH]n12,CHEMBL1992673,4.7 |
| CN1CCN(c2ccc(C(=O)Nc3[nH]nc4ccc(Cc5cc(F)cc(F)c5)cc34)c(NC3CCOCC3)c2)CC1,CHEMBL1983268,7.4 |
| NC(=O)c1cn(-c2ccc(O)cc2Cl)c2cc(-c3ccncc3)ccc2c1=O,CHEMBL340384,6.4 |
| CN(C)C1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1,CHEMBL1969151,6.3 |
| COC(=O)c1c(N)nc2ccccn12,CHEMBL1981492,4.1 |
| Cn1cc(-c2cc3nc(Br)cnc3[nH]2)c2cc(F)ccc21,CHEMBL1993335,6.2 |
| CC(C)NC1=NNC(=O)C1=Cc1cc2ccccc2[nH]1,CHEMBL1988692,6.1 |
| Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1,CHEMBL1970317,8.7 |
| Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4c3c(N)nn4C)cc2)c1,CHEMBL1985491,8.7 |
| N#Cc1ncc2nc1OCCCCOc1cc(NCc3cncs3)c(Cl)cc1NC(=O)N2,CHEMBL248757,8.9 |
| Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN(C)C)cnc(N)c34)cc2)c1,CHEMBL1979883,7.9 |
| COCCOC1CCC(n2nc(-c3ccc(Nc4nc5cc(C)cc(C)c5o4)cc3)c3c(N)ncnc32)CC1,CHEMBL1984162,7.2 |
| COc1ccc(CN(C)C)cc1Nc1nccc(-c2c(-c3cccc(NC(=O)c4c(F)cccc4F)c3)nc3sccn23)n1,CHEMBL1997051,5.9 |
| Fc1cnc(Nc2ccccc2)nc1Nc1ccccc1,CHEMBL491758,7.1 |
| O=C1Nc2ccccc2C1=Cc1c[nH]c2ccccc12,CHEMBL1986590,6.2 |
| Cc1cc(C)cc(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)c1,CHEMBL371206,6.8 |
| COc1ccc(C=NNc2ncnc3c2[nH]c2ccccc23)cc1OC,CHEMBL1974664,8.0 |
| c1ccc(-c2ccnc3[nH]ccc23)cc1,CHEMBL482538,5.0 |
| COc1ccc(-c2cc3nccn3c(Nc3ncccc3C(N)=O)n2)cc1OC,CHEMBL1190711,6.2 |
| Nc1[nH]nc2cccc(-c3ccc(Br)cc3)c12,CHEMBL1990346,5.9 |
| CNCC#Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12,CHEMBL1964441,8.3 |
| Cc1cc(C(N)=O)n2nc(C(C)(C)C)cc2n1,CHEMBL1986684,5.4 |
| ON=C(c1nc2ccccc2[nH]1)c1nc2ccccc2[nH]1,CHEMBL546797,5.9 |
| Cc1ccc(F)c(NC(=O)Nc2ccc(-c3ccc(OCCCn4cccc4)c4n[nH]c(N)c34)cc2)c1,CHEMBL2007266,7.8 |
| Cc1ccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)cc2)cc1C,CHEMBL2000335,6.9 |
| Nc1nc(=O)[nH]c2sccc12,CHEMBL2007097,4.4 |
| Cn1cc(-c2cnn3c(N)c(-c4ccc(NC(=O)Nc5cccc(C(F)(F)F)c5)cc4)cnc23)cn1,CHEMBL1988717,8.2 |
| Cc1cccc(Nc2nc(NC3CCCCC3N)cnc2C(N)=O)c1,CHEMBL1974328,6.0 |
| Cc1cnc(Nc2nc(NC(C)C)ncc2Br)s1,CHEMBL1973013,6.3 |
| CCC(N)(C#Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12)CC,CHEMBL1983025,7.5 |
| COc1ccc(-n2ccc3cnc(Nc4cc(OC)c(OC)c(OC)c4)nc32)cc1,CHEMBL1975927,8.3 |
| Nc1[nH]nc2cccc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(F)c3)c12,CHEMBL1980904,8.5 |
| CC(Nc1cncc(-n2cnc3ccc(C#N)cc32)n1)c1ccccc1F,CHEMBL1977138,6.6 |
| COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC,CHEMBL1241473,7.9 |
| c1ccc(C2CCc3[nH]ncc3C2)cc1,CHEMBL2000879,4.3 |
| COC(=O)c1ccccc1-c1ccc2c(c1)Nc1ccccc1NC2=O,CHEMBL2004513,5.9 |
| CN(C)c1ccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCOCC4)c3)n2)cc1NC(=O)Cc1ccccc1,CHEMBL1969483,6.2 |
| O=C1Nc2cc(-c3ccc(O)cc3)ccc2C1=Cc1ccc[nH]1,CHEMBL1980329,5.9 |
| c1nc(-c2ccc3c(c2)OCO3)c2cc[nH]c2n1,CHEMBL2004515,4.9 |
| CCN(CC)CC#Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12,CHEMBL2001257,7.6 |
| Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cncc4n[nH]c(N)c34)cc2)c1,CHEMBL271441,9.1 |
| COc1cc(-c2csc3c(C=CC(=O)NCCN(C)C)cnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C,CHEMBL1989267,7.1 |
| Nc1ncnc2scc(-c3ccc(NC(=O)Nc4ccccc4)cc3)c12,CHEMBL1967531,6.7 |
| C#Cc1cn(C2CCCC2)c2ncnc(N)c12,CHEMBL1993877,5.9 |
| Cc1cc(NC(=O)Nc2ccc(-c3ccnc4n[nH]c(N)c34)cc2)ccc1F,CHEMBL273187,9.5 |
| CCc1c(-c2ccc(C(C)(C)O)cc2)[nH]c2nccnc12,CHEMBL1976420,5.8 |
| Cc1cc(NC(=O)Nc2ccc(-c3cccc4n[nH]c(N)c34)c(F)c2)ccc1F,CHEMBL1986979,8.8 |
| N#Cc1ncc2nc1OCCCCCOc1cc(OCCO)c(Cl)cc1NC(=O)N2,CHEMBL413779,7.6 |
| CN1CCN(Cc2ccc3c(c2)Cc2c-3n[nH]c2-c2csc(C#CCOCC3CC3)c2)CC1,CHEMBL2002446,8.5 |
| Cc1ccccc1-c1c(-c2ccc3n[nH]c(N)c3c2)nnn1Cc1ccccc1,CHEMBL2000029,5.8 |
| Cc1cc(O)ccc1-n1cc(C(N)=O)c(=O)c2ccc(-c3ccncc3)cc21,CHEMBL340921,6.0 |
| N#Cc1ncc2nc1OCCCCCOc1cc(OCCCO)c(Cl)cc1NC(=O)N2,CHEMBL373598,7.4 |
| CCOc1ccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCOCC4)c3)n2)cc1NC(=O)Cc1ccccc1,CHEMBL2000078,5.9 |
| O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1,CHEMBL1973540,6.6 |
| COc1ccc2c(c1)c(-c1cc3nc(Br)cnc3[nH]1)cn2C,CHEMBL2005478,5.8 |
| COc1cccc(OC)c1CNc1nc(NC2CCCCC2)nc2ccc(Cl)cc12,CHEMBL1996646,6.5 |
| c1ccc(-c2cccc3nccn23)cc1,CHEMBL1992723,4.1 |
| O=C(Cc1ccccc1)Nc1cc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCOCC4)c3)n2)ccc1Cl,CHEMBL2005482,6.8 |
| Cc1ccccc1Nc1nccc(-c2c(-c3cccc(NC(=O)Cc4ccccc4)c3)nc3sccn23)n1,CHEMBL1997909,7.1 |
| N#Cc1ccc2c(c1)C(c1ccc3c(n1)CCCC3O)C(=O)N2,CHEMBL1985681,6.9 |
| Cc1ccc(-c2ccc(NC(=O)Nc3cccc(Br)c3)cc2)c2c(N)[nH]nc12,CHEMBL1973937,7.8 |
| OC1CCC(Nc2cc(Cl)nc(-c3c[nH]c4ncccc34)n2)CC1,CHEMBL1991674,6.7 |
| Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cn[nH]c5)cnc(N)c34)cc2)c1,CHEMBL1969102,8.6 |
| CCc1nc(Nc2ccc(N3CCOCC3)c(Cl)c2)nc2[nH]ccc12,CHEMBL2004118,5.8 |
| CNC(=O)N1CCN(CCCOc2ccc3c(c2)-c2[nH]nc(-c4ccc(C#N)nc4)c2C3)CC1,CHEMBL2001998,6.4 |
| COc1cc(C=C(C#N)c2nc3ccccc3[nH]2)c(Br)cc1O,CHEMBL1994241,5.7 |
| CS(=O)(=O)Nc1cc2c(cc1Cl)NC(=O)Nc1cnc(C#N)c(n1)OCCCCCO2,CHEMBL223460,7.8 |
| O=C1Cc2c([nH]c3ccc([N+](=O)[O-])cc23)-c2ccccc2N1,CHEMBL50894,6.0 |
| Cc1cnc(Nc2cccc(S(N)(=O)=O)c2)nc1Nc1ccc(OCC(N)=O)cc1,CHEMBL1988838,6.5 |
| CCN1CCN(c2ccc(Nc3nccc(-c4c(-c5cccc(C(=O)Nc6ccccc6F)c5)nc5ccccn45)n3)cc2)CC1,CHEMBL1981725,7.5 |
| Cc1cccc(NC(=O)Nc2ccc(-c3cccc4n[nH]cc34)cc2)c1,CHEMBL375284,8.6 |
| COc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(CC(O)CO)c5)cnc(N)c34)cc2)cc1,CHEMBL1965170,8.4 |
| CCNC(=O)c1[nH]nc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(OC)cc1,CHEMBL365617,5.9 |
| CCOc1nc(C(=O)NCc2ccncc2)cc(N)c1C#N,CHEMBL1984206,5.8 |
| Nc1c(-c2ccccc2)c2cc(Cl)ccc2[nH]c1=O,CHEMBL462120,6.7 |
| Nc1ncc(-c2ccoc2)c2scc(-c3ccc(NC(=O)Nc4ccccc4F)cc3)c12,CHEMBL1965570,6.7 |
| COc1c(-c2nc3ccccc3[nH]2)c(O)cc2oc(C)cc(=O)c12,CHEMBL1972355,5.7 |
| CC(C)(O)c1cn(-c2ccc3n[nH]cc3c2)nn1,CHEMBL2001641,4.4 |
| Cc1ccc(-c2cc(-c3cc(Br)ccc3O)[nH]c(=O)c2C#N)s1,CHEMBL1997193,6.4 |
| CCNc1nc(C)c(-c2ccnc(Nc3ccc(N4CCN(C(C)=O)CC4)cc3)n2)s1,CHEMBL1983715,7.6 |
| O=C(Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCCC4=O)c3)n2)c1)c1c(F)cccc1F,CHEMBL2006715,6.1 |
| NC(=O)c1cccc2[nH]c(-c3ccc(NC(=O)c4cccc(S(=O)(=O)N5CCOCC5)c4)cc3)nc12,CHEMBL1986597,6.0 |
| Cc1cccc(NC(=O)Nc2ccc(-c3cccc4n[nH]c(N)c34)cc2)c1,CHEMBL220057,8.4 |
| CC(C)Cc1nc(Nc2ccc(N3CCOCC3)c(Cl)c2)nc2[nH]ccc12,CHEMBL1980763,6.3 |
| CC(=O)c1ccccc1-c1ncnc2[nH]ccc12,CHEMBL1977931,4.2 |
| COc1cc(-c2nn(C3CCC(N4CCN(C(C)=O)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C,CHEMBL1970879,6.1 |
| Cc1cc(C)c(C=C2C(=O)Nc3ccccc32)[nH]1,CHEMBL2002702,7.7 |
| Nc1ncc(-c2cnn(CCO)c2)c2scc(-c3ccc(NC(=O)Nc4ccc(OC(F)F)cc4)cc3)c12,CHEMBL1972220,8.0 |
| Fc1cccc(CNc2ncnc3nc[nH]c23)c1,CHEMBL2003785,4.5 |
| NC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1,CHEMBL1973720,6.9 |
| Cc1cccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)c1,CHEMBL1969523,5.9 |
| Cn1nc(N)c2c(-c3ccc(NC(=O)Nc4ccc(F)c(C(F)(F)F)c4)cc3)ccnc21,CHEMBL1966836,8.4 |
| COCCOCC#Cc1cc(-c2[nH]nc3c2C(=O)c2cc(CN4CCN(C)CC4)ccc2-3)cs1,CHEMBL387971,7.8 |
| O=c1[nH]c2ccc(Cl)cc2c(-c2ccccc2)c1C1=NNC(c2ccccc2)C1,CHEMBL1992796,5.6 |
| N#Cc1ncc2nc1OCCCCCOc1cc(OCC(O)CO)c(Cl)cc1NC(=O)N2,CHEMBL223257,7.0 |
| CC(NC(=O)c1ccc(-c2ccncc2)cc1)c1ccccc1,CHEMBL1999428,5.6 |
| Cc1cccc(NC(=O)Nc2ccc(-c3noc4ncnc(N)c34)cc2)c1,CHEMBL211378,7.8 |
| Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN5CCOCC5)cnc(N)c34)cc2)c1,CHEMBL1982465,8.1 |
| Cc1cccc(NC(=O)Nc2ccc(-c3cncc4n[nH]c(N)c34)cc2)c1,CHEMBL272938,9.2 |
| CC(=O)Nc1ccc(-n2nc3ccc(N)nc3n2)cc1,CHEMBL2002723,5.7 |
| COc1ccc(NC(=O)Nc2ccc(-c3cccc4onc(N)c34)cc2)cc1Cl,CHEMBL272453,6.8 |
| Cc1cccc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)cc2)c1,CHEMBL185569,7.2 |
| Clc1cc(-c2c[nH]c3ncccc23)cc(NCc2ccccc2)n1,CHEMBL1969588,6.8 |
| COc1cc(Nc2nccc(Nc3cc(C4CCCCC4)no3)n2)cc(OC)c1OC,CHEMBL1984711,7.6 |
| Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1,CHEMBL1967878,6.9 |
| CCC1CC(NS(=O)(=O)C2CC2)CC1c1ncc2cnc3[nH]ccc3n12,CHEMBL1992073,5.8 |
| Nc1ncnc2sccc12,CHEMBL1972934,4.9 |
| O=C(Cc1ccc(-c2cccnc2)cc1)Nc1ccc(SC(F)F)cc1,CHEMBL1992581,5.8 |
| COc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(CC(C)(C)O)c5)cnc(N)c34)cc2)cc1,CHEMBL2004290,8.2 |
| Nc1[nH]nc2ccc(-c3nnn(Cc4ccccc4)c3-c3ccc(F)cc3)cc12,CHEMBL1986499,5.6 |
| C#Cc1cc2c(cc1OC)-c1[nH]nc(-c3ccc(C#N)nc3)c1C2,CHEMBL1972250,5.6 |
| Nc1[nH]nc2nccc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12,CHEMBL403402,8.8 |
| NC(=O)c1cccc2[nH]c(-c3ccc(C4CCCCN4)cc3F)nc12,CHEMBL1089101,5.7 |
| C=Cc1ccc(-c2cccc3nnc(N)n23)cc1,CHEMBL1983573,5.2 |
| Cc1cc(C)cc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)c(C)c2)c1,CHEMBL2004311,6.2 |
| CC(=O)c1c(-c2ccccc2)nn(C)c(=O)c1N,CHEMBL1984402,4.1 |
| Cc1ccc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1,CHEMBL1988075,8.0 |
| Cc1ccccc1Nc1nccc(-c2c(-c3cccc(NC(=O)c4ccccc4)c3)nc3sccn23)n1,CHEMBL1988076,6.9 |
| Nc1ncnc2c1N=C(c1ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc1)CCN2,CHEMBL260092,6.7 |
| Cc1[nH]nc2ncc(C#N)c(-c3ccccc3)c12,CHEMBL1965495,7.2 |
| Cc1cc(C)cc(NC(=O)Nc2ccc(-c3cccc4sncc34)cc2)c1,CHEMBL1992242,7.2 |
| O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3n[nH]cc3c2)n1,CHEMBL396523,6.3 |
| Cc1cc(C)cc(NC(=O)Nc2ccc(NC(=O)c3csc4ncnc(N)c34)cc2)c1,CHEMBL1970203,5.8 |
| CNC(=O)C=Cc1cnc(N)c2c(-c3ccc4sc(C)nc4c3)csc12,CHEMBL1968590,8.4 |
| c1cnc2[nH]cc(-c3ccnc(NC4CCCCC4)n3)c2c1,CHEMBL385478,7.0 |
| CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(N3CCN(C(C)=O)CC3)ccc2OC)ncc1Br,CHEMBL1971029,6.8 |
| Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)c12,CHEMBL394790,6.0 |
| COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(=O)O)s3)c2cc1OC,CHEMBL474432,6.2 |
| Nc1[nH]nc2c(OCCCn3cccc3)ccc(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)c12,CHEMBL1965387,7.5 |
| Cc1cc(-c2ncnc3[nH]ccc23)ccc1F,CHEMBL1997041,5.5 |
| NC(=O)c1cc2c(-c3ccccc3)cncc2s1,CHEMBL1999556,5.6 |
| CNC(=O)c1ccccc1Sc1ccc2c(C=Cc3ccccn3)[nH]nc2c1,CHEMBL1988437,7.1 |
| Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CC(C)(C)N)cnc(N)c34)cc2)c1,CHEMBL1979577,8.1 |
| Nc1ncnc2c1C(=O)NCCN2,CHEMBL1992607,4.1 |
| N#Cc1ncc2nc1OCC(O)C(O)COc1ccc(Cl)cc1NC(=O)N2,CHEMBL1980802,6.8 |
| CCN(CC)CCCNC(=O)c1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)csc12,CHEMBL1996649,8.6 |
| CCCCOc1ncnc2[nH]cc(-c3ccccc3)c12,CHEMBL1996817,6.5 |
| Cc1cc(C)cc(NC(=O)Nc2ccc(-c3cccc4onc(N)c34)cc2)c1,CHEMBL409349,8.4 |
| CCOc1nc(C(=O)NCc2ccc(S(N)(=O)=O)cc2)cc(N)c1C#N,CHEMBL2004355,6.7 |
| Cc1cc(C)c2oc(Nc3ccc(-c4cccc(C(N)=O)c4N)cc3F)nc2c1,CHEMBL1990884,6.4 |
| CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c1C,CHEMBL1990885,8.6 |
| Nc1c(-c2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ccc2nccnc12,CHEMBL2004438,7.6 |
| COc1ccc(-c2ccc(NC(=O)Nc3cccc(Br)c3)cc2)c2c(N)noc12,CHEMBL271381,7.1 |
| Cc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)cc1,CHEMBL1982466,8.1 |
| NC(=O)c1ccc2nc(-c3ccc([N+](=O)[O-])o3)cn2c1,CHEMBL1973359,5.9 |
| Cc1cccc(NC(=O)Nc2ccc(-c3cccc4n[nH]c(N)c34)c(F)c2)c1,CHEMBL1994638,8.8 |
| Cn1nc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)ccnc21,CHEMBL1985888,8.6 |
| CN1CCN(c2ccc(Nc3ncc(Cl)c(Nc4ccc5n[nH]cc5c4)n3)cc2)CC1,CHEMBL1979690,7.8 |
| COc1cc(C=C(C#N)c2nc3ccc(C)cc3[nH]2)c(Br)cc1O,CHEMBL2000345,5.9 |
| O=C(NN=Cc1cc(Br)c(O)c(Br)c1)Nc1ccccc1,CHEMBL1983575,7.5 |
| Cn1c2ccccc2c2c3c(c4c5ccccc5n(CCC#N)c4c21)CNC3=O,CHEMBL302449,5.8 |
| Cc1[nH]c(C=C2C(=O)Nc3ccccc32)c(C)c1CCC(=O)O,CHEMBL2007064,7.0 |
| COC(C(=O)N1Cc2n[nH]c(NC(=O)c3ccc(N4CCN(C)CC4)cc3)c2C1)c1ccccc1,CHEMBL1981047,6.8 |
| CC(C)Nc1nccc(Nc2ncc(-c3ccccc3)s2)n1,CHEMBL2002432,6.2 |
| O=C1Cc2cc(-c3ccccc3)cnc2N1,CHEMBL1983630,4.2 |
| COc1ccc(-c2ccc(NC(=O)Nc3ccc(F)c(C)c3)cc2)c2c(N)noc12,CHEMBL1979093,6.3 |
| COCCOC1CCC(n2nc(-c3ccc(Nc4nc5cc(C)cc(Cl)c5o4)cc3)c3c(N)ncnc32)CC1,CHEMBL1987054,7.0 |
| Nc1ncc(-c2ccncc2)c2scc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12,CHEMBL1970083,7.7 |
| CNC(=O)c1cnc(N)c2c(-c3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)csc12,CHEMBL2005631,8.5 |
| Nc1ncc(C=CC(=O)NCCCn2ccnc2)c2scc(-c3ccc(Br)cc3)c12,CHEMBL1994938,7.3 |
| Nc1cc(=O)[nH]n1-c1ccccn1,CHEMBL1995765,4.8 |
| CC(C)(C)C(=O)Oc1ccc2c(c1)nc(NC(=O)c1cccc([N+](=O)[O-])c1)n2CCCO,CHEMBL1236126,5.7 |
| CCCNC(=O)c1ccc(Nc2nc(CCC(F)(F)F)c3cc[nH]c3n2)cc1,CHEMBL1984760,6.0 |
| NC(=O)c1cc2c(-c3ccc(F)cc3F)cncc2s1,CHEMBL1975787,5.7 |
| Brc1ccc2n[nH]c(-c3ccccc3)c2c1,CHEMBL1994074,5.9 |
| Cc1ccc(Nc2nc3ccc([N+](=O)[O-])cc3[nH]2)nc1,CHEMBL1992937,6.1 |
| NC(=O)c1cccc2c[nH]nc12,CHEMBL451401,4.8 |
| Cc1cc(C)cc(NC(=O)Nc2ccc(-c3ccnc4c3c(N)nn4C)cc2)c1,CHEMBL1986507,8.7 |
| Cc1cc(Nc2cc(N3CCN(C)CC3)nc(C=Cc3ccccc3)n2)[nH]n1,CHEMBL1983923,6.9 |
| O=C(Nc1ccc(-c2cccc3sncc23)cc1)Nc1ccc(F)c(C(F)(F)F)c1,CHEMBL2000801,6.5 |
| CN1CCN(c2cccc(Nc3nccc(-c4c(C(N)=O)nc5ccccn45)n3)c2)CC1,CHEMBL1971245,6.1 |
| Nc1ncc(-c2ccoc2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12,CHEMBL1966514,7.8 |
| O=C1Cc2c([nH]c3ccc(Br)cc23)-c2ccccc2N1,CHEMBL296586,5.7 |
| N#Cc1ccc2nc(N)n(-c3nc(-c4ccccc4)cs3)c2c1,CHEMBL1996066,6.4 |
| Nc1[nH]nc2cccc(-c3ccc(NC(=O)Nc4cc(C(=O)O)ccc4F)cc3)c12,CHEMBL1993722,6.0 |
| Cc1[nH]nc2ccc(-c3cccnc3)cc12,CHEMBL1967252,4.5 |
| CC(C)C(C)Nc1ncc(Cl)c(Nc2nccs2)n1,CHEMBL1993374,6.3 |
| N#Cc1c(O)[nH]c(=O)c2c(=N)oc3ccc(Cl)cc3c12,CHEMBL1973711,6.4 |
| CC(C)(C(N)=O)n1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1,CHEMBL1967720,8.3 |
| CCNC(=O)c1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)csc12,CHEMBL1979516,7.3 |
| CN(C)c1ccc(-c2cc(-c3ccc([N+](=O)[O-])cc3)nc(NS(=O)(=O)c3ccc(N)cc3)n2)cc1,CHEMBL1980167,5.7 |
| CCOc1nc(C(=O)NCc2ccccc2S(N)(=O)=O)cc(N)c1C#N,CHEMBL377408,6.2 |
| Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(Br)c4)cc3)c12,CHEMBL1976220,6.1 |
| Cc1ccc(C(=O)Nc2ccon2)cc1Nc1ncnc2c1cnn2-c1ccccc1,CHEMBL259922,7.6 |
| CN1CCN(C2CCC(n3cc(-c4ccc(Oc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1,CHEMBL1997617,7.8 |
| NCc1cc(Nc2ncnc(-c3ccccc3)n2)ccc1O,CHEMBL1980246,5.8 |
| Cc1cc(NC(=O)Nc2ccc(-c3cccc4n[nH]c(N)c34)cc2)ccc1F,CHEMBL374044,9.0 |
| Nc1nccc2scc(-c3ccc(NC(=O)Nc4ccccc4C(F)(F)F)cc3)c12,CHEMBL1987910,6.7 |
| O=C(Nc1nc2ccccc2s1)c1cccc2c1CN(c1nc(C(=O)O)c(-c3ccc(CO)cc3)s1)CC2,CHEMBL1983980,5.8 |
| CNc1nc(C)c(-c2ccnc(Nc3ccc(N4CCNCC4)cc3)n2)s1,CHEMBL1999484,7.2 |
| Nc1ncc(-c2cnn(CCO)c2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12,CHEMBL1980297,8.5 |
| Cn1nc(N)c2c(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)cncc21,CHEMBL404366,9.5 |
| Cc1ccc(NCc2ccc(-c3ccc(F)cc3)nc2)cc1,CHEMBL1986899,7.0 |
| Cc1cc(OCC2CCC(C(=O)O)C2)c(NC(=O)Nc2cnc(C#N)cn2)cc1Cl,CHEMBL1991285,6.0 |
| Cc1cc2cc(-c3csc4c(-c5cccc(S(C)(=O)=O)c5)cnc(N)c34)ccc2[nH]1,CHEMBL1997822,7.4 |
| O=C(O)c1ccccc1Nc1ccnc(Nc2cccc(O)c2)n1,CHEMBL243088,6.5 |
| O=C(Nc1cnc2[nH]cc(-c3ccccc3)c2c1)c1cccc(F)c1F,CHEMBL1974416,5.9 |
| CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl,CHEMBL1993661,6.8 |
| COc1cc2c(cc1F)C(c1ccccc1Cl)=Nc1c(C)n[nH]c1N2,CHEMBL1980391,6.1 |
| C[C@@H](O)Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1,CHEMBL2022856,8.5 |
| CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4ccncc4)cc3)n2)c(=O)c1=O,CHEMBL2205426,5.68 |
| Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1NC(=O)CCN1CCN(C)CC1,CHEMBL3288854,6.64 |
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