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Upload datasets

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cta_asap_100.json ADDED
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cta_cite_100.json ADDED
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cta_scrna_full.json ADDED
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drp_scrna_100.json ADDED
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pda_scatac.json ADDED
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+ [
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing CCND3 in K562 cells cause the expression of SDE2 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing NEDD8 in K562 cells cause the expression of GFI1B to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing ZNF326 in K562 cells cause the expression of ELF1 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Down"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing ZNF326 in K562 cells cause the expression of SMARCAD1 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Down"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing YIPF5 in K562 cells cause the expression of PTGS1 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing UFM1 in K562 cells cause the expression of CCNE2 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Down"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing QARS in K562 cells cause the expression of PCM1 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing FARSB in K562 cells cause the expression of IFI35 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing HSD17B12 in K562 cells cause the expression of TMEM50B to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Down"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing DNAJC19 in K562 cells cause the expression of TTC19 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing SEC61G in K562 cells cause the expression of TNRC6B to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing SLC39A7 in K562 cells cause the expression of SLC39A10 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing ZNF326 in K562 cells cause the expression of SPEN to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Down"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing XRN1 in K562 cells cause the expression of PRPF3 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing IDH3A in K562 cells cause the expression of WDR26 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing TTI1 in K562 cells cause the expression of HIST1H2AE to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing DARS in K562 cells cause the expression of ASNS to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing TTI1 in K562 cells cause the expression of CDCA7 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Down"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing SEC63 in K562 cells cause the expression of WBP1L to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing TTI2 in K562 cells cause the expression of S100A1 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
327
+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing BHLHE40 in K562 cells cause the expression of HOXB2 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Down"
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+ }
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+ ]
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+ },
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+ {
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+ "messages": [
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+ {
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+ "role": "system",
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+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
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+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing CHERP in K562 cells cause the expression of ZCCHC6 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
347
+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
351
+ }
352
+ ]
353
+ },
354
+ {
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+ "messages": [
356
+ {
357
+ "role": "system",
358
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
359
+ },
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+ {
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+ "role": "user",
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+ "content": "Does perturbing AARS in K562 cells cause the expression of FAM129A to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
363
+ },
364
+ {
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+ "role": "assistant",
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+ "content": "Up"
367
+ }
368
+ ]
369
+ },
370
+ {
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+ "messages": [
372
+ {
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+ "role": "system",
374
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
375
+ },
376
+ {
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+ "role": "user",
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+ "content": "Does perturbing XRN1 in K562 cells cause the expression of DEF6 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
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+ },
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+ {
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+ "role": "assistant",
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+ "content": "Up"
383
+ }
384
+ ]
385
+ },
386
+ {
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+ "messages": [
388
+ {
389
+ "role": "system",
390
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
391
+ },
392
+ {
393
+ "role": "user",
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+ "content": "Does perturbing CREB1 in K562 cells cause the expression of ZBTB43 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
395
+ },
396
+ {
397
+ "role": "assistant",
398
+ "content": "Down"
399
+ }
400
+ ]
401
+ },
402
+ {
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+ "messages": [
404
+ {
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+ "role": "system",
406
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
407
+ },
408
+ {
409
+ "role": "user",
410
+ "content": "Does perturbing SEC61B in K562 cells cause the expression of OS9 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
411
+ },
412
+ {
413
+ "role": "assistant",
414
+ "content": "Up"
415
+ }
416
+ ]
417
+ },
418
+ {
419
+ "messages": [
420
+ {
421
+ "role": "system",
422
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
423
+ },
424
+ {
425
+ "role": "user",
426
+ "content": "Does perturbing AARS in K562 cells cause the expression of PSAT1 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
427
+ },
428
+ {
429
+ "role": "assistant",
430
+ "content": "Up"
431
+ }
432
+ ]
433
+ },
434
+ {
435
+ "messages": [
436
+ {
437
+ "role": "system",
438
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
439
+ },
440
+ {
441
+ "role": "user",
442
+ "content": "Does perturbing TMED10 in K562 cells cause the expression of GALNT7 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
443
+ },
444
+ {
445
+ "role": "assistant",
446
+ "content": "Up"
447
+ }
448
+ ]
449
+ },
450
+ {
451
+ "messages": [
452
+ {
453
+ "role": "system",
454
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
455
+ },
456
+ {
457
+ "role": "user",
458
+ "content": "Does perturbing IER3IP1 in K562 cells cause the expression of ARFGAP3 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
459
+ },
460
+ {
461
+ "role": "assistant",
462
+ "content": "Up"
463
+ }
464
+ ]
465
+ },
466
+ {
467
+ "messages": [
468
+ {
469
+ "role": "system",
470
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
471
+ },
472
+ {
473
+ "role": "user",
474
+ "content": "Does perturbing SARS in K562 cells cause the expression of TGIF1 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
475
+ },
476
+ {
477
+ "role": "assistant",
478
+ "content": "Down"
479
+ }
480
+ ]
481
+ },
482
+ {
483
+ "messages": [
484
+ {
485
+ "role": "system",
486
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
487
+ },
488
+ {
489
+ "role": "user",
490
+ "content": "Does perturbing SPCS3 in K562 cells cause the expression of GNPTAB to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
491
+ },
492
+ {
493
+ "role": "assistant",
494
+ "content": "Up"
495
+ }
496
+ ]
497
+ },
498
+ {
499
+ "messages": [
500
+ {
501
+ "role": "system",
502
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
503
+ },
504
+ {
505
+ "role": "user",
506
+ "content": "Does perturbing TIMM44 in K562 cells cause the expression of SIL1 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
507
+ },
508
+ {
509
+ "role": "assistant",
510
+ "content": "Up"
511
+ }
512
+ ]
513
+ },
514
+ {
515
+ "messages": [
516
+ {
517
+ "role": "system",
518
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
519
+ },
520
+ {
521
+ "role": "user",
522
+ "content": "Does perturbing BHLHE40 in K562 cells cause the expression of ATF4 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
523
+ },
524
+ {
525
+ "role": "assistant",
526
+ "content": "Down"
527
+ }
528
+ ]
529
+ },
530
+ {
531
+ "messages": [
532
+ {
533
+ "role": "system",
534
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
535
+ },
536
+ {
537
+ "role": "user",
538
+ "content": "Does perturbing COPZ1 in K562 cells cause the expression of FNDC3A to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
539
+ },
540
+ {
541
+ "role": "assistant",
542
+ "content": "Up"
543
+ }
544
+ ]
545
+ },
546
+ {
547
+ "messages": [
548
+ {
549
+ "role": "system",
550
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
551
+ },
552
+ {
553
+ "role": "user",
554
+ "content": "Does perturbing EIF2S1 in K562 cells cause the expression of AHNAK to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
555
+ },
556
+ {
557
+ "role": "assistant",
558
+ "content": "Down"
559
+ }
560
+ ]
561
+ },
562
+ {
563
+ "messages": [
564
+ {
565
+ "role": "system",
566
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
567
+ },
568
+ {
569
+ "role": "user",
570
+ "content": "Does perturbing BHLHE40 in K562 cells cause the expression of ZBTB11 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
571
+ },
572
+ {
573
+ "role": "assistant",
574
+ "content": "Down"
575
+ }
576
+ ]
577
+ },
578
+ {
579
+ "messages": [
580
+ {
581
+ "role": "system",
582
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
583
+ },
584
+ {
585
+ "role": "user",
586
+ "content": "Does perturbing EIF2S1 in K562 cells cause the expression of XRN1 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
587
+ },
588
+ {
589
+ "role": "assistant",
590
+ "content": "Up"
591
+ }
592
+ ]
593
+ },
594
+ {
595
+ "messages": [
596
+ {
597
+ "role": "system",
598
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
599
+ },
600
+ {
601
+ "role": "user",
602
+ "content": "Does perturbing DERL2 in K562 cells cause the expression of TMC6 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
603
+ },
604
+ {
605
+ "role": "assistant",
606
+ "content": "Up"
607
+ }
608
+ ]
609
+ },
610
+ {
611
+ "messages": [
612
+ {
613
+ "role": "system",
614
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
615
+ },
616
+ {
617
+ "role": "user",
618
+ "content": "Does perturbing PPWD1 in K562 cells cause the expression of ANKRD12 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
619
+ },
620
+ {
621
+ "role": "assistant",
622
+ "content": "Up"
623
+ }
624
+ ]
625
+ },
626
+ {
627
+ "messages": [
628
+ {
629
+ "role": "system",
630
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
631
+ },
632
+ {
633
+ "role": "user",
634
+ "content": "Does perturbing DDIT3 in K562 cells cause the expression of ARID5A to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
635
+ },
636
+ {
637
+ "role": "assistant",
638
+ "content": "Down"
639
+ }
640
+ ]
641
+ },
642
+ {
643
+ "messages": [
644
+ {
645
+ "role": "system",
646
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
647
+ },
648
+ {
649
+ "role": "user",
650
+ "content": "Does perturbing HYOU1 in K562 cells cause the expression of ASCC3 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
651
+ },
652
+ {
653
+ "role": "assistant",
654
+ "content": "Up"
655
+ }
656
+ ]
657
+ },
658
+ {
659
+ "messages": [
660
+ {
661
+ "role": "system",
662
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
663
+ },
664
+ {
665
+ "role": "user",
666
+ "content": "Does perturbing DDIT3 in K562 cells cause the expression of CEBPB to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
667
+ },
668
+ {
669
+ "role": "assistant",
670
+ "content": "Down"
671
+ }
672
+ ]
673
+ },
674
+ {
675
+ "messages": [
676
+ {
677
+ "role": "system",
678
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
679
+ },
680
+ {
681
+ "role": "user",
682
+ "content": "Does perturbing SARS in K562 cells cause the expression of PRRC2B to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
683
+ },
684
+ {
685
+ "role": "assistant",
686
+ "content": "Up"
687
+ }
688
+ ]
689
+ },
690
+ {
691
+ "messages": [
692
+ {
693
+ "role": "system",
694
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
695
+ },
696
+ {
697
+ "role": "user",
698
+ "content": "Does perturbing TMED2 in K562 cells cause the expression of GOLIM4 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
699
+ },
700
+ {
701
+ "role": "assistant",
702
+ "content": "Up"
703
+ }
704
+ ]
705
+ },
706
+ {
707
+ "messages": [
708
+ {
709
+ "role": "system",
710
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
711
+ },
712
+ {
713
+ "role": "user",
714
+ "content": "Does perturbing HSPA9 in K562 cells cause the expression of DDX39A to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
715
+ },
716
+ {
717
+ "role": "assistant",
718
+ "content": "Down"
719
+ }
720
+ ]
721
+ },
722
+ {
723
+ "messages": [
724
+ {
725
+ "role": "system",
726
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
727
+ },
728
+ {
729
+ "role": "user",
730
+ "content": "Does perturbing DDIT3 in K562 cells cause the expression of CEBPG to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
731
+ },
732
+ {
733
+ "role": "assistant",
734
+ "content": "Down"
735
+ }
736
+ ]
737
+ },
738
+ {
739
+ "messages": [
740
+ {
741
+ "role": "system",
742
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
743
+ },
744
+ {
745
+ "role": "user",
746
+ "content": "Does perturbing TMED10 in K562 cells cause the expression of TRIP11 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
747
+ },
748
+ {
749
+ "role": "assistant",
750
+ "content": "Up"
751
+ }
752
+ ]
753
+ },
754
+ {
755
+ "messages": [
756
+ {
757
+ "role": "system",
758
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
759
+ },
760
+ {
761
+ "role": "user",
762
+ "content": "Does perturbing SARS in K562 cells cause the expression of KLF3 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
763
+ },
764
+ {
765
+ "role": "assistant",
766
+ "content": "Up"
767
+ }
768
+ ]
769
+ },
770
+ {
771
+ "messages": [
772
+ {
773
+ "role": "system",
774
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
775
+ },
776
+ {
777
+ "role": "user",
778
+ "content": "Does perturbing SEC61A1 in K562 cells cause the expression of ORAI3 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
779
+ },
780
+ {
781
+ "role": "assistant",
782
+ "content": "Up"
783
+ }
784
+ ]
785
+ },
786
+ {
787
+ "messages": [
788
+ {
789
+ "role": "system",
790
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
791
+ },
792
+ {
793
+ "role": "user",
794
+ "content": "Does perturbing HSPA5 in K562 cells cause the expression of CRYAB to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
795
+ },
796
+ {
797
+ "role": "assistant",
798
+ "content": "Down"
799
+ }
800
+ ]
801
+ },
802
+ {
803
+ "messages": [
804
+ {
805
+ "role": "system",
806
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
807
+ },
808
+ {
809
+ "role": "user",
810
+ "content": "Does perturbing DDRGK1 in K562 cells cause the expression of DDRGK1 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
811
+ },
812
+ {
813
+ "role": "assistant",
814
+ "content": "Down"
815
+ }
816
+ ]
817
+ },
818
+ {
819
+ "messages": [
820
+ {
821
+ "role": "system",
822
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
823
+ },
824
+ {
825
+ "role": "user",
826
+ "content": "Does perturbing SLMO2 in K562 cells cause the expression of PITPNB to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
827
+ },
828
+ {
829
+ "role": "assistant",
830
+ "content": "Up"
831
+ }
832
+ ]
833
+ },
834
+ {
835
+ "messages": [
836
+ {
837
+ "role": "system",
838
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
839
+ },
840
+ {
841
+ "role": "user",
842
+ "content": "Does perturbing SLMO2 in K562 cells cause the expression of SLMO2 to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
843
+ },
844
+ {
845
+ "role": "assistant",
846
+ "content": "Down"
847
+ }
848
+ ]
849
+ },
850
+ {
851
+ "messages": [
852
+ {
853
+ "role": "system",
854
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
855
+ },
856
+ {
857
+ "role": "user",
858
+ "content": "Does perturbing CAD in K562 cells cause the expression of CAD to upregulate or downregulate? Make your answer in format 'Final Answer: Up' or 'Final Answer: Down'."
859
+ },
860
+ {
861
+ "role": "assistant",
862
+ "content": "Down"
863
+ }
864
+ ]
865
+ }
866
+ ]
psa_scatac.json ADDED
@@ -0,0 +1,962 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ [
2
+ {
3
+ "messages": [
4
+ {
5
+ "role": "system",
6
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
7
+ },
8
+ {
9
+ "role": "user",
10
+ "content": "Does perturbing HARS in K562 cells cause significant changes in the expression of SAMD9? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
11
+ },
12
+ {
13
+ "role": "assistant",
14
+ "content": "No"
15
+ }
16
+ ]
17
+ },
18
+ {
19
+ "messages": [
20
+ {
21
+ "role": "system",
22
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
23
+ },
24
+ {
25
+ "role": "user",
26
+ "content": "Does perturbing CCND3 in K562 cells cause significant changes in the expression of SDE2? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
27
+ },
28
+ {
29
+ "role": "assistant",
30
+ "content": "Yes"
31
+ }
32
+ ]
33
+ },
34
+ {
35
+ "messages": [
36
+ {
37
+ "role": "system",
38
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
39
+ },
40
+ {
41
+ "role": "user",
42
+ "content": "Does perturbing PSMD4 in K562 cells cause significant changes in the expression of MYCN? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
43
+ },
44
+ {
45
+ "role": "assistant",
46
+ "content": "No"
47
+ }
48
+ ]
49
+ },
50
+ {
51
+ "messages": [
52
+ {
53
+ "role": "system",
54
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
55
+ },
56
+ {
57
+ "role": "user",
58
+ "content": "Does perturbing SEC61B in K562 cells cause significant changes in the expression of NBEAL2? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
59
+ },
60
+ {
61
+ "role": "assistant",
62
+ "content": "No"
63
+ }
64
+ ]
65
+ },
66
+ {
67
+ "messages": [
68
+ {
69
+ "role": "system",
70
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
71
+ },
72
+ {
73
+ "role": "user",
74
+ "content": "Does perturbing EIF2B2 in K562 cells cause significant changes in the expression of ARHGAP9? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
75
+ },
76
+ {
77
+ "role": "assistant",
78
+ "content": "No"
79
+ }
80
+ ]
81
+ },
82
+ {
83
+ "messages": [
84
+ {
85
+ "role": "system",
86
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
87
+ },
88
+ {
89
+ "role": "user",
90
+ "content": "Does perturbing EIF2B4 in K562 cells cause significant changes in the expression of G3BP2? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
91
+ },
92
+ {
93
+ "role": "assistant",
94
+ "content": "No"
95
+ }
96
+ ]
97
+ },
98
+ {
99
+ "messages": [
100
+ {
101
+ "role": "system",
102
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
103
+ },
104
+ {
105
+ "role": "user",
106
+ "content": "Does perturbing NEDD8 in K562 cells cause significant changes in the expression of GFI1B? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
107
+ },
108
+ {
109
+ "role": "assistant",
110
+ "content": "Yes"
111
+ }
112
+ ]
113
+ },
114
+ {
115
+ "messages": [
116
+ {
117
+ "role": "system",
118
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
119
+ },
120
+ {
121
+ "role": "user",
122
+ "content": "Does perturbing EIF2B3 in K562 cells cause significant changes in the expression of DNAJB4? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
123
+ },
124
+ {
125
+ "role": "assistant",
126
+ "content": "No"
127
+ }
128
+ ]
129
+ },
130
+ {
131
+ "messages": [
132
+ {
133
+ "role": "system",
134
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
135
+ },
136
+ {
137
+ "role": "user",
138
+ "content": "Does perturbing CARS in K562 cells cause significant changes in the expression of CUL9? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
139
+ },
140
+ {
141
+ "role": "assistant",
142
+ "content": "No"
143
+ }
144
+ ]
145
+ },
146
+ {
147
+ "messages": [
148
+ {
149
+ "role": "system",
150
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
151
+ },
152
+ {
153
+ "role": "user",
154
+ "content": "Does perturbing ZNF326 in K562 cells cause significant changes in the expression of ELF1? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
155
+ },
156
+ {
157
+ "role": "assistant",
158
+ "content": "Yes"
159
+ }
160
+ ]
161
+ },
162
+ {
163
+ "messages": [
164
+ {
165
+ "role": "system",
166
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
167
+ },
168
+ {
169
+ "role": "user",
170
+ "content": "Does perturbing ZNF326 in K562 cells cause significant changes in the expression of SMARCAD1? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
171
+ },
172
+ {
173
+ "role": "assistant",
174
+ "content": "Yes"
175
+ }
176
+ ]
177
+ },
178
+ {
179
+ "messages": [
180
+ {
181
+ "role": "system",
182
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
183
+ },
184
+ {
185
+ "role": "user",
186
+ "content": "Does perturbing EIF2B3 in K562 cells cause significant changes in the expression of C6orf106? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
187
+ },
188
+ {
189
+ "role": "assistant",
190
+ "content": "No"
191
+ }
192
+ ]
193
+ },
194
+ {
195
+ "messages": [
196
+ {
197
+ "role": "system",
198
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
199
+ },
200
+ {
201
+ "role": "user",
202
+ "content": "Does perturbing STT3A in K562 cells cause significant changes in the expression of IKZF2? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
203
+ },
204
+ {
205
+ "role": "assistant",
206
+ "content": "No"
207
+ }
208
+ ]
209
+ },
210
+ {
211
+ "messages": [
212
+ {
213
+ "role": "system",
214
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
215
+ },
216
+ {
217
+ "role": "user",
218
+ "content": "Does perturbing YIPF5 in K562 cells cause significant changes in the expression of PTGS1? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
219
+ },
220
+ {
221
+ "role": "assistant",
222
+ "content": "Yes"
223
+ }
224
+ ]
225
+ },
226
+ {
227
+ "messages": [
228
+ {
229
+ "role": "system",
230
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
231
+ },
232
+ {
233
+ "role": "user",
234
+ "content": "Does perturbing DARS in K562 cells cause significant changes in the expression of RIOK2? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
235
+ },
236
+ {
237
+ "role": "assistant",
238
+ "content": "No"
239
+ }
240
+ ]
241
+ },
242
+ {
243
+ "messages": [
244
+ {
245
+ "role": "system",
246
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
247
+ },
248
+ {
249
+ "role": "user",
250
+ "content": "Does perturbing OST4 in K562 cells cause significant changes in the expression of SEC63? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
251
+ },
252
+ {
253
+ "role": "assistant",
254
+ "content": "No"
255
+ }
256
+ ]
257
+ },
258
+ {
259
+ "messages": [
260
+ {
261
+ "role": "system",
262
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
263
+ },
264
+ {
265
+ "role": "user",
266
+ "content": "Does perturbing UFM1 in K562 cells cause significant changes in the expression of CCNE2? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
267
+ },
268
+ {
269
+ "role": "assistant",
270
+ "content": "Yes"
271
+ }
272
+ ]
273
+ },
274
+ {
275
+ "messages": [
276
+ {
277
+ "role": "system",
278
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
279
+ },
280
+ {
281
+ "role": "user",
282
+ "content": "Does perturbing SRP68 in K562 cells cause significant changes in the expression of CD3EAP? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
283
+ },
284
+ {
285
+ "role": "assistant",
286
+ "content": "No"
287
+ }
288
+ ]
289
+ },
290
+ {
291
+ "messages": [
292
+ {
293
+ "role": "system",
294
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
295
+ },
296
+ {
297
+ "role": "user",
298
+ "content": "Does perturbing FARSB in K562 cells cause significant changes in the expression of DOK3? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
299
+ },
300
+ {
301
+ "role": "assistant",
302
+ "content": "No"
303
+ }
304
+ ]
305
+ },
306
+ {
307
+ "messages": [
308
+ {
309
+ "role": "system",
310
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
311
+ },
312
+ {
313
+ "role": "user",
314
+ "content": "Does perturbing FARSB in K562 cells cause significant changes in the expression of ORAI2? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
315
+ },
316
+ {
317
+ "role": "assistant",
318
+ "content": "No"
319
+ }
320
+ ]
321
+ },
322
+ {
323
+ "messages": [
324
+ {
325
+ "role": "system",
326
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
327
+ },
328
+ {
329
+ "role": "user",
330
+ "content": "Does perturbing TIMM44 in K562 cells cause significant changes in the expression of NFKBIE? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
331
+ },
332
+ {
333
+ "role": "assistant",
334
+ "content": "No"
335
+ }
336
+ ]
337
+ },
338
+ {
339
+ "messages": [
340
+ {
341
+ "role": "system",
342
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
343
+ },
344
+ {
345
+ "role": "user",
346
+ "content": "Does perturbing GNPNAT1 in K562 cells cause significant changes in the expression of DOCK11? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
347
+ },
348
+ {
349
+ "role": "assistant",
350
+ "content": "No"
351
+ }
352
+ ]
353
+ },
354
+ {
355
+ "messages": [
356
+ {
357
+ "role": "system",
358
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
359
+ },
360
+ {
361
+ "role": "user",
362
+ "content": "Does perturbing GMPPB in K562 cells cause significant changes in the expression of TUBB3? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
363
+ },
364
+ {
365
+ "role": "assistant",
366
+ "content": "No"
367
+ }
368
+ ]
369
+ },
370
+ {
371
+ "messages": [
372
+ {
373
+ "role": "system",
374
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
375
+ },
376
+ {
377
+ "role": "user",
378
+ "content": "Does perturbing CHERP in K562 cells cause significant changes in the expression of NAV1? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
379
+ },
380
+ {
381
+ "role": "assistant",
382
+ "content": "No"
383
+ }
384
+ ]
385
+ },
386
+ {
387
+ "messages": [
388
+ {
389
+ "role": "system",
390
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
391
+ },
392
+ {
393
+ "role": "user",
394
+ "content": "Does perturbing QARS in K562 cells cause significant changes in the expression of PCM1? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
395
+ },
396
+ {
397
+ "role": "assistant",
398
+ "content": "Yes"
399
+ }
400
+ ]
401
+ },
402
+ {
403
+ "messages": [
404
+ {
405
+ "role": "system",
406
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
407
+ },
408
+ {
409
+ "role": "user",
410
+ "content": "Does perturbing CARS in K562 cells cause significant changes in the expression of ASRGL1? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
411
+ },
412
+ {
413
+ "role": "assistant",
414
+ "content": "No"
415
+ }
416
+ ]
417
+ },
418
+ {
419
+ "messages": [
420
+ {
421
+ "role": "system",
422
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
423
+ },
424
+ {
425
+ "role": "user",
426
+ "content": "Does perturbing CARS in K562 cells cause significant changes in the expression of ZNF672? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
427
+ },
428
+ {
429
+ "role": "assistant",
430
+ "content": "No"
431
+ }
432
+ ]
433
+ },
434
+ {
435
+ "messages": [
436
+ {
437
+ "role": "system",
438
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
439
+ },
440
+ {
441
+ "role": "user",
442
+ "content": "Does perturbing FARSB in K562 cells cause significant changes in the expression of IFI35? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
443
+ },
444
+ {
445
+ "role": "assistant",
446
+ "content": "Yes"
447
+ }
448
+ ]
449
+ },
450
+ {
451
+ "messages": [
452
+ {
453
+ "role": "system",
454
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
455
+ },
456
+ {
457
+ "role": "user",
458
+ "content": "Does perturbing SEC61B in K562 cells cause significant changes in the expression of GDPD5? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
459
+ },
460
+ {
461
+ "role": "assistant",
462
+ "content": "No"
463
+ }
464
+ ]
465
+ },
466
+ {
467
+ "messages": [
468
+ {
469
+ "role": "system",
470
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
471
+ },
472
+ {
473
+ "role": "user",
474
+ "content": "Does perturbing SRP72 in K562 cells cause significant changes in the expression of ANKRD33? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
475
+ },
476
+ {
477
+ "role": "assistant",
478
+ "content": "No"
479
+ }
480
+ ]
481
+ },
482
+ {
483
+ "messages": [
484
+ {
485
+ "role": "system",
486
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
487
+ },
488
+ {
489
+ "role": "user",
490
+ "content": "Does perturbing SEL1L in K562 cells cause significant changes in the expression of KIAA1919? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
491
+ },
492
+ {
493
+ "role": "assistant",
494
+ "content": "No"
495
+ }
496
+ ]
497
+ },
498
+ {
499
+ "messages": [
500
+ {
501
+ "role": "system",
502
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
503
+ },
504
+ {
505
+ "role": "user",
506
+ "content": "Does perturbing CHERP in K562 cells cause significant changes in the expression of CLINT1? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
507
+ },
508
+ {
509
+ "role": "assistant",
510
+ "content": "No"
511
+ }
512
+ ]
513
+ },
514
+ {
515
+ "messages": [
516
+ {
517
+ "role": "system",
518
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
519
+ },
520
+ {
521
+ "role": "user",
522
+ "content": "Does perturbing HSD17B12 in K562 cells cause significant changes in the expression of TMEM50B? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
523
+ },
524
+ {
525
+ "role": "assistant",
526
+ "content": "Yes"
527
+ }
528
+ ]
529
+ },
530
+ {
531
+ "messages": [
532
+ {
533
+ "role": "system",
534
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
535
+ },
536
+ {
537
+ "role": "user",
538
+ "content": "Does perturbing SRPR in K562 cells cause significant changes in the expression of RAB33A? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
539
+ },
540
+ {
541
+ "role": "assistant",
542
+ "content": "No"
543
+ }
544
+ ]
545
+ },
546
+ {
547
+ "messages": [
548
+ {
549
+ "role": "system",
550
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
551
+ },
552
+ {
553
+ "role": "user",
554
+ "content": "Does perturbing DNAJC19 in K562 cells cause significant changes in the expression of TTC19? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
555
+ },
556
+ {
557
+ "role": "assistant",
558
+ "content": "Yes"
559
+ }
560
+ ]
561
+ },
562
+ {
563
+ "messages": [
564
+ {
565
+ "role": "system",
566
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
567
+ },
568
+ {
569
+ "role": "user",
570
+ "content": "Does perturbing PDIA6 in K562 cells cause significant changes in the expression of C14orf1? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
571
+ },
572
+ {
573
+ "role": "assistant",
574
+ "content": "No"
575
+ }
576
+ ]
577
+ },
578
+ {
579
+ "messages": [
580
+ {
581
+ "role": "system",
582
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
583
+ },
584
+ {
585
+ "role": "user",
586
+ "content": "Does perturbing SEC61G in K562 cells cause significant changes in the expression of TNRC6B? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
587
+ },
588
+ {
589
+ "role": "assistant",
590
+ "content": "Yes"
591
+ }
592
+ ]
593
+ },
594
+ {
595
+ "messages": [
596
+ {
597
+ "role": "system",
598
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
599
+ },
600
+ {
601
+ "role": "user",
602
+ "content": "Does perturbing PDIA6 in K562 cells cause significant changes in the expression of PPL? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
603
+ },
604
+ {
605
+ "role": "assistant",
606
+ "content": "No"
607
+ }
608
+ ]
609
+ },
610
+ {
611
+ "messages": [
612
+ {
613
+ "role": "system",
614
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
615
+ },
616
+ {
617
+ "role": "user",
618
+ "content": "Does perturbing MANF in K562 cells cause significant changes in the expression of ZNF175? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
619
+ },
620
+ {
621
+ "role": "assistant",
622
+ "content": "No"
623
+ }
624
+ ]
625
+ },
626
+ {
627
+ "messages": [
628
+ {
629
+ "role": "system",
630
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
631
+ },
632
+ {
633
+ "role": "user",
634
+ "content": "Does perturbing SLC39A7 in K562 cells cause significant changes in the expression of SLC39A10? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
635
+ },
636
+ {
637
+ "role": "assistant",
638
+ "content": "Yes"
639
+ }
640
+ ]
641
+ },
642
+ {
643
+ "messages": [
644
+ {
645
+ "role": "system",
646
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
647
+ },
648
+ {
649
+ "role": "user",
650
+ "content": "Does perturbing AMIGO3 in K562 cells cause significant changes in the expression of C1orf162? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
651
+ },
652
+ {
653
+ "role": "assistant",
654
+ "content": "No"
655
+ }
656
+ ]
657
+ },
658
+ {
659
+ "messages": [
660
+ {
661
+ "role": "system",
662
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
663
+ },
664
+ {
665
+ "role": "user",
666
+ "content": "Does perturbing SEC61G in K562 cells cause significant changes in the expression of TMEM156? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
667
+ },
668
+ {
669
+ "role": "assistant",
670
+ "content": "No"
671
+ }
672
+ ]
673
+ },
674
+ {
675
+ "messages": [
676
+ {
677
+ "role": "system",
678
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
679
+ },
680
+ {
681
+ "role": "user",
682
+ "content": "Does perturbing ARHGAP22 in K562 cells cause significant changes in the expression of CCDC6? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
683
+ },
684
+ {
685
+ "role": "assistant",
686
+ "content": "No"
687
+ }
688
+ ]
689
+ },
690
+ {
691
+ "messages": [
692
+ {
693
+ "role": "system",
694
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
695
+ },
696
+ {
697
+ "role": "user",
698
+ "content": "Does perturbing CCND3 in K562 cells cause significant changes in the expression of NFKBIE? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
699
+ },
700
+ {
701
+ "role": "assistant",
702
+ "content": "No"
703
+ }
704
+ ]
705
+ },
706
+ {
707
+ "messages": [
708
+ {
709
+ "role": "system",
710
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
711
+ },
712
+ {
713
+ "role": "user",
714
+ "content": "Does perturbing GNPNAT1 in K562 cells cause significant changes in the expression of TMCO1? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
715
+ },
716
+ {
717
+ "role": "assistant",
718
+ "content": "No"
719
+ }
720
+ ]
721
+ },
722
+ {
723
+ "messages": [
724
+ {
725
+ "role": "system",
726
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
727
+ },
728
+ {
729
+ "role": "user",
730
+ "content": "Does perturbing SLC35B1 in K562 cells cause significant changes in the expression of SEC31A? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
731
+ },
732
+ {
733
+ "role": "assistant",
734
+ "content": "No"
735
+ }
736
+ ]
737
+ },
738
+ {
739
+ "messages": [
740
+ {
741
+ "role": "system",
742
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
743
+ },
744
+ {
745
+ "role": "user",
746
+ "content": "Does perturbing COPB1 in K562 cells cause significant changes in the expression of TMEM2? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
747
+ },
748
+ {
749
+ "role": "assistant",
750
+ "content": "No"
751
+ }
752
+ ]
753
+ },
754
+ {
755
+ "messages": [
756
+ {
757
+ "role": "system",
758
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
759
+ },
760
+ {
761
+ "role": "user",
762
+ "content": "Does perturbing SEC63 in K562 cells cause significant changes in the expression of SLC44A5? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
763
+ },
764
+ {
765
+ "role": "assistant",
766
+ "content": "No"
767
+ }
768
+ ]
769
+ },
770
+ {
771
+ "messages": [
772
+ {
773
+ "role": "system",
774
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
775
+ },
776
+ {
777
+ "role": "user",
778
+ "content": "Does perturbing ASCC3 in K562 cells cause significant changes in the expression of N4BP2? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
779
+ },
780
+ {
781
+ "role": "assistant",
782
+ "content": "No"
783
+ }
784
+ ]
785
+ },
786
+ {
787
+ "messages": [
788
+ {
789
+ "role": "system",
790
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
791
+ },
792
+ {
793
+ "role": "user",
794
+ "content": "Does perturbing ZNF326 in K562 cells cause significant changes in the expression of SPEN? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
795
+ },
796
+ {
797
+ "role": "assistant",
798
+ "content": "Yes"
799
+ }
800
+ ]
801
+ },
802
+ {
803
+ "messages": [
804
+ {
805
+ "role": "system",
806
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
807
+ },
808
+ {
809
+ "role": "user",
810
+ "content": "Does perturbing PDIA6 in K562 cells cause significant changes in the expression of HM13? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
811
+ },
812
+ {
813
+ "role": "assistant",
814
+ "content": "No"
815
+ }
816
+ ]
817
+ },
818
+ {
819
+ "messages": [
820
+ {
821
+ "role": "system",
822
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
823
+ },
824
+ {
825
+ "role": "user",
826
+ "content": "Does perturbing PSMD4 in K562 cells cause significant changes in the expression of GADD45G? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
827
+ },
828
+ {
829
+ "role": "assistant",
830
+ "content": "No"
831
+ }
832
+ ]
833
+ },
834
+ {
835
+ "messages": [
836
+ {
837
+ "role": "system",
838
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
839
+ },
840
+ {
841
+ "role": "user",
842
+ "content": "Does perturbing SRPRB in K562 cells cause significant changes in the expression of SUCO? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
843
+ },
844
+ {
845
+ "role": "assistant",
846
+ "content": "No"
847
+ }
848
+ ]
849
+ },
850
+ {
851
+ "messages": [
852
+ {
853
+ "role": "system",
854
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
855
+ },
856
+ {
857
+ "role": "user",
858
+ "content": "Does perturbing ASCC3 in K562 cells cause significant changes in the expression of PDK2? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
859
+ },
860
+ {
861
+ "role": "assistant",
862
+ "content": "No"
863
+ }
864
+ ]
865
+ },
866
+ {
867
+ "messages": [
868
+ {
869
+ "role": "system",
870
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
871
+ },
872
+ {
873
+ "role": "user",
874
+ "content": "Does perturbing IER3IP1 in K562 cells cause significant changes in the expression of POMP? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
875
+ },
876
+ {
877
+ "role": "assistant",
878
+ "content": "No"
879
+ }
880
+ ]
881
+ },
882
+ {
883
+ "messages": [
884
+ {
885
+ "role": "system",
886
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
887
+ },
888
+ {
889
+ "role": "user",
890
+ "content": "Does perturbing TMEM167A in K562 cells cause significant changes in the expression of SMAGP? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
891
+ },
892
+ {
893
+ "role": "assistant",
894
+ "content": "No"
895
+ }
896
+ ]
897
+ },
898
+ {
899
+ "messages": [
900
+ {
901
+ "role": "system",
902
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
903
+ },
904
+ {
905
+ "role": "user",
906
+ "content": "Does perturbing XRN1 in K562 cells cause significant changes in the expression of PRPF3? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
907
+ },
908
+ {
909
+ "role": "assistant",
910
+ "content": "Yes"
911
+ }
912
+ ]
913
+ },
914
+ {
915
+ "messages": [
916
+ {
917
+ "role": "system",
918
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
919
+ },
920
+ {
921
+ "role": "user",
922
+ "content": "Does perturbing ASCC3 in K562 cells cause significant changes in the expression of MLKL? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
923
+ },
924
+ {
925
+ "role": "assistant",
926
+ "content": "No"
927
+ }
928
+ ]
929
+ },
930
+ {
931
+ "messages": [
932
+ {
933
+ "role": "system",
934
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
935
+ },
936
+ {
937
+ "role": "user",
938
+ "content": "Does perturbing EIF2B4 in K562 cells cause significant changes in the expression of ST5? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
939
+ },
940
+ {
941
+ "role": "assistant",
942
+ "content": "No"
943
+ }
944
+ ]
945
+ },
946
+ {
947
+ "messages": [
948
+ {
949
+ "role": "system",
950
+ "content": "You are an expert who knows a lot about single cell biology and genomics and will help me solve a series of tasks related to single cell data analysis."
951
+ },
952
+ {
953
+ "role": "user",
954
+ "content": "Does perturbing SLC39A7 in K562 cells cause significant changes in the expression of FCGRT? Make your answer in format 'Final Answer: Yes' or 'Final Answer: No'."
955
+ },
956
+ {
957
+ "role": "assistant",
958
+ "content": "No"
959
+ }
960
+ ]
961
+ }
962
+ ]