id stringlengths 13 13 | source_index int64 0 673 | protein_id stringlengths 71 71 | instruction stringlengths 313 2.79k | reference stringlengths 47 7.79k | sequence_length int64 47 7.79k | go_molecular_function listlengths 1 28 | interpro listlengths 1 113 |
|---|---|---|---|---|---|---|---|
ipr_go-000000 | 0 | sha256:669119f3660e25802e4d9d5d3abdcf25e9feb3666a00e1d4a9a294493841e494 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to BKACE, BKACE that shares evolutionary origin and functional similarity; 2. The protein should be classified within Aldolase_TIM sharing conserved structural features; 3. The protein must be a... | MATKRKVIITCAPTGAIHTPSMSPYLPVTPQQIGDAALAAAKEGAAIIHLHARDPDDGHPTQDPAVFQEFLPRIKAECDAVINLTTGGSPHMTVAERLKPAHHFQPEVASLNMGSMNFGLYPMLERFKELKYDWERKHLENSRDLVFKNTFADIEYILTSCGANGTRFEFECYDISHLYNLAHFVDRGLAKPPFFVQSVFGLLGGIGAHPEDLAHMRRTADRLFGKDYVWSILGAGRNQIPLASIGVAQGSNARVGLEDSLWIEPGKLAESSAAQVRKIRQVIEGLSLDIATPAEAREMLQLKGAANTNF | 310 | [
{
"id": "GO:0043720",
"name": "3-keto-5-aminohexanoate cleavage activity "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
}
] | [
{
"id": "IPR008567",
"name": "BKACE",
"type": "FAMILY",
"begin": 6,
"end": 303
},
{
"id": "IPR013785",
"name": "Aldolase_TIM",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 1,
"end": 310
},
{
"id": "IPR008567",
"name": "BKACE",
"type": "FAMILY",
"begin": ... |
ipr_go-000001 | 1 | sha256:c96fb96cf353a2a45daf7d7220a05907ec80320af9f23fca1b4787e65147800e | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more 4Fe4S_Fe-S-bd, 4Fe4S_Fe-S-bd, 4Fe4S_Fe-S-bd, 4Fe4S_Fe-S-bd, 4Fe4S_Fe-S-bd that are essential for its biological function; 2. The protein should belong to RnfB_subfamily that shares ... | MSEEVQERIWILITPDKCSGCRLCEVTCSLEHEGIIWPEASRIRVFELFPGINVPHTCVQCPDYPCVNACPTNALSVDEKTGAVVVNEEKCITCGACVLACPGKVPRIPAGKGSVVICDLCGGNPKCVEICHEAGHDALKIVTGNYRPIYRTFAKDPQEKSLDIARKVFGEDF | 173 | [
{
"id": "GO:0051539",
"name": "4 iron, 4 sulfur cluster binding "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
},
{
"id": "GO:0016491",
"name": " oxidoreductase activity "
}
] | [
{
"id": "IPR017896",
"name": "4Fe4S_Fe-S-bd",
"type": "DOMAIN",
"begin": 9,
"end": 40
},
{
"id": "IPR017896",
"name": "4Fe4S_Fe-S-bd",
"type": "DOMAIN",
"begin": 48,
"end": 80
},
{
"id": "IPR017900",
"name": "4Fe4S_Fe_S_CS",
"type": "CONSERVED_SITE",
"... |
ipr_go-000002 | 2 | sha256:da4575a63eb192d39787f6fd7f81a2eac11b723684e0276f6772d5de325f4bdf | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more ABC_transporter-like_ATP-bd, Chromo/chromo_shadow_dom, ABC_transporter-like_ATP-bd, ABC_transporter-like_ATP-bd, ABC_transporter-like_ATP-bd, AAA+_ATPase, AAA+_ATPase, eEF3_ABC2_chr... | MAPAATAAASSGKGSFDLATLFVADKAARDEAGLALADAVKKSGVEFFTQIGFNDAIVKALNDKKSQSAREGACEVISTLCENGAAQLLEPHVISSAENTPFPALLEAFADKVAAVKTAAIAAVKAIVQSMNPWASFVLLPALLNLIRTSGKWQIKAGSLEILQQLITSAPYQMGEAMPDLVPVLAGAVWDTKSDVKKAAKATLEKAVSLVENKDIEKFVPALVKSLLNPIEEVPKTISLLSATTFVSEVTAPTISLIAPLLIRGLDERPTATKRKVCVIADNMSKLVDSEYTVRPFLPQLLPRLIKTAETIADPEARSV... | 1,055 | [
{
"id": "GO:0005524",
"name": "ATP binding "
},
{
"id": "GO:0016887",
"name": " ATP hydrolysis activity "
},
{
"id": "GO:0003723",
"name": " RNA binding "
},
{
"id": "GO:0003746",
"name": " translation elongation factor activity "
}
] | [
{
"id": "IPR003439",
"name": "ABC_transporter-like_ATP-bd",
"type": "DOMAIN",
"begin": 705,
"end": 936
},
{
"id": "IPR000953",
"name": "Chromo/chromo_shadow_dom",
"type": "DOMAIN",
"begin": 816,
"end": 872
},
{
"id": "IPR050611",
"name": "ABCF_EF3_subfamily",
... |
ipr_go-000003 | 3 | sha256:408c66280f8d66988edb935017c4298e17cf223293ee87d6ef970a50d0651da9 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more NMB0315-like_N, Peptidase_M23 that are essential for its biological function; 2. The protein should belong to Cell_wall_metabolism_enzyme that shares evolutionary origin and functio... | MAVFPLSAKHRKYALRALAVSIILVSAAYIASTERTERVRPQRVEQNLPPLSWGGSGVQTAYWVQEAVQPGDSLADVLARSGMARDEIARITEKYGGEADLRHLRADQSVHVLVGGDGGAREVQFFTDEDGERNLVALEKKGGIWRRSASEADMKVLPTLRSVVVKTSARGSLARAEVPVEIRESLSGIFAGRFSLDGLKEGDAVRLMYDSLYFHGQQVAAGDILAAEVVKGGTRHQAFYYRSDKEGGGGGNYYDEDGKVLQEKGGFNIEPLVYTRISSPFGYRMHPILHTWRLHTGIDYAAPQGTPVRASADGVITFKG... | 430 | [
{
"id": "GO:0046872",
"name": "metal ion binding "
},
{
"id": "GO:0004222",
"name": " metalloendopeptidase activity "
}
] | [
{
"id": "IPR050570",
"name": "Cell_wall_metabolism_enzyme",
"type": "FAMILY",
"begin": 19,
"end": 390
},
{
"id": "IPR054512",
"name": "NMB0315-like_N",
"type": "DOMAIN",
"begin": 61,
"end": 143
},
{
"id": "IPR011055",
"name": "Dup_hybrid_motif",
"type": "H... |
ipr_go-000004 | 4 | sha256:5a15a639dfbeeeb3377f43c662b97fda9aac823ffdf24464b2814658f4bd331d | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more AsnC-type_HTH_dom, AsnC-type_HTH_dom, AsnC-type_HTH_dom, AsnC-type_HTH_dom, AsnC-type_HTH_dom, Tscrpt_reg_AsnC/Lrp_C that are essential for its biological function; 2. The protein s... | MDRLDDTDERILAELAEHARATFAEIGHKVSLSAPAVKRRVDRMLESGVIKGFTTVVDRNALGWNTEAYVQIFCHGRIAPDQLRAAWVNIPEVVSAATVTGTSDAILHVLAHDMRHLEAALERIRSSADVERSESTVVLSNLIDRMPP | 148 | [
{
"id": "GO:0043565",
"name": "sequence-specific DNA binding "
}
] | [
{
"id": "IPR000485",
"name": "AsnC-type_HTH_dom",
"type": "DOMAIN",
"begin": 20,
"end": 31
},
{
"id": "IPR000485",
"name": "AsnC-type_HTH_dom",
"type": "DOMAIN",
"begin": 4,
"end": 20
},
{
"id": "IPR000485",
"name": "AsnC-type_HTH_dom",
"type": "DOMAIN",
... |
ipr_go-000005 | 5 | sha256:50594be59aa7852dcdccd4fd13825b239fed46dff2ce31a488ef868edb881b3b | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PLipase_A2_dom, PLipase_A2_dom that are essential for its biological function; 2. The protein should be classified within PLipase_A2_dom_sf, PLipase_A2_dom_sf sharing conserved stru... | MHALRSSVLALWLCLHVSVRAWMTYRSANGLDEYEPEDRIIFLGTKWCGNGNVAEGPEDLGPLKETDACCREHDMCPDLIAAGQSKHGLTNTASYTRLNCGCDEKFYNCLKNSAETGSGAVRFTYFTVLGTKCYRNEHPLICVKKGWFSCSKYELDKSQPKRYQWFDVSSNFAFPRMLT | 179 | [
{
"id": "GO:0046872",
"name": "metal ion binding "
},
{
"id": "GO:0004623",
"name": " phospholipase A2 activity "
},
{
"id": "GO:0090729",
"name": " toxin activity "
}
] | [
{
"id": "IPR033113",
"name": "PLipase_A2_His_AS",
"type": "ACTIVE_SITE",
"begin": 69,
"end": 76
},
{
"id": "IPR016090",
"name": "PLipase_A2_dom",
"type": "DOMAIN",
"begin": 42,
"end": 136
},
{
"id": "IPR036444",
"name": "PLipase_A2_dom_sf",
"type": "HOMOLO... |
ipr_go-000006 | 6 | sha256:341197d06eae7bdb9b8490afd8b9a74228a2641a42ddea4ea0c0078a4eb3a2cc | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GNAT_dom that are essential for its biological function; 2. The protein should be classified within Acyl_CoA_acyltransferase sharing conserved structural features; 3. The protein mu... | MISTPEPLHAGHILTPFCCGVDSIDNWLKQRAMKNQTTGASRTFVCCGSDSNVLAYYSLASSAVTTNTSPGRFRRNMPDPIPVVVLGRLAVDKSLHGQGVARALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYQRVGFVPSPMDPMMLMVTLGDLVESV | 163 | [
{
"id": "GO:0016747",
"name": "acyltransferase activity, transferring groups other than amino-acyl groups "
},
{
"id": "GO:0000049",
"name": " tRNA binding "
}
] | [
{
"id": "IPR016181",
"name": "Acyl_CoA_acyltransferase",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 26,
"end": 151
},
{
"id": "IPR000182",
"name": "GNAT_dom",
"type": "DOMAIN",
"begin": 85,
"end": 143
}
] |
ipr_go-000007 | 7 | sha256:bfff69d1d7d031108e1c50bbb606696118d87057cab6e04b802323f2c0487534 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more ABC_transporter-like_ATP-bd, DrrA1-3-like_C, AAA+_ATPase, ABC_transporter-like_ATP-bd that are essential for its biological function; 2. The protein should belong to ABC_transporter... | MADTAITVDGAEKRYGDKKALDGLDLRVARGTVHGVLGPNGAGKTTLVRVLSTLLRPDAGRIEVSGHDVVREAYAVRLRIGLLGQHAALDEELGGRQNLELFGRLHHLGARRARARADELLERFDLADTGRKTVRQYSGGMRRRLDLAASLITEPEVLFLDEPTTGLDPRGRAEVWDSVRSLVGGGTTVLLTTQYLEEADQLADRISVVDAGRVIAEGTADELKAETGGDRIDVVLREAGQLGAAVALLPLTGVTVDTDRRLLSAPVTDRMEALSGVVRALQEAGIEAEDVALRRPTLDEVFLHLTGDDRRVKEAA | 316 | [
{
"id": "GO:0005524",
"name": "ATP binding "
},
{
"id": "GO:0016887",
"name": " ATP hydrolysis activity "
}
] | [
{
"id": "IPR050763",
"name": "ABC_transporter_ATP-binding",
"type": "FAMILY",
"begin": 4,
"end": 310
},
{
"id": "IPR003439",
"name": "ABC_transporter-like_ATP-bd",
"type": "DOMAIN",
"begin": 21,
"end": 165
},
{
"id": "IPR005894",
"name": "DrrA",
"type": "F... |
ipr_go-000008 | 8 | sha256:9af3f057a63063df67b1505a5dd7494c95280d99f3fa45c9786ad221469f52c2 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Elp3/MiaA/NifB-like_rSAM, Cobalamin-bd, rSAM, Cobalamin-bd that are essential for its biological function; 2. The protein should belong to ThnK-like, Tetrapyrrole_Bchl_Biosynth_MTs,... | MTVPAARSGRKVYFIGLNAVPFLPLVAGLLRTYAEQDPRVAAGYDFQEPVFLVDGVQEMAAGITDPDVLALSCYVWNFRRQMKVARLVKERHPGMLVVAGGPHVPDRPGDFFARHPYVDVLVHGEGETAFRELLIERLADHPDYTRVPGVSVRHGTEAVPGRPAERLPRRIETPSPYLLGVMDGAVATCRQRDLRFYALWETNRGCPYSCAFCDWGSATMSALRLFDAERLQEEIEWFAEHDVEDLFVCDANFGILPRDLEIARALADARAATGAPKLIRVNFAKNSNDRVFEISKTWHDADLLMGTTLSMQSTDLDVLE... | 681 | [
{
"id": "GO:0051539",
"name": "4 iron, 4 sulfur cluster binding "
},
{
"id": "GO:0031419",
"name": " cobalamin binding "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
},
{
"id": "GO:0008168",
"name": " methyltransferase activity "
}
] | [
{
"id": "IPR036724",
"name": "Cobalamin-bd_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 64,
"end": 139
},
{
"id": "IPR006638",
"name": "Elp3/MiaA/NifB-like_rSAM",
"type": "DOMAIN",
"begin": 196,
"end": 414
},
{
"id": "IPR023404",
"name": "rSAM_horseshoe",
... |
ipr_go-000009 | 9 | sha256:2ca962384eab52f63840ebe294f20a563ed32fb8966a77e2f1c8c7c091f6e9f3 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more DrrA1-3-like_C, ABC_transporter-like_ATP-bd, AAA+_ATPase, ABC_transporter-like_ATP-bd that are essential for its biological function; 2. The protein should belong to DrrA, ABC_trans... | MDGYAVRAEAMEKRYGEKRALDGFDLAVGEGTVHGLLGPNGAGKTTAVRILSTLVRLDGGRATVAGLDVARQPREVRARIGLTGQYAAVDEVLTGRQNLEMFGRLFHLGGRRARLRATELLEQFDLTDAGDRGVGKYSGGMRRRLDLAASMILAPAVLFLDEPTTGLDPRSRGEVWESVRALVAGGTTVLLTTQYLEEADKLASRITVIDQGRAIADDTPDGLKNLVGGDRIEVVVAERAEIPRVVKVVARVADGEPEADETESRVHAPVTDRVTALTEVARTLQDEGVRVEDIGLRRPSLDDVFLRLTGHRTENTEAKE... | 322 | [
{
"id": "GO:0005524",
"name": "ATP binding "
},
{
"id": "GO:0016887",
"name": " ATP hydrolysis activity "
}
] | [
{
"id": "IPR025302",
"name": "DrrA1-3-like_C",
"type": "DOMAIN",
"begin": 219,
"end": 308
},
{
"id": "IPR003439",
"name": "ABC_transporter-like_ATP-bd",
"type": "DOMAIN",
"begin": 21,
"end": 165
},
{
"id": "IPR027417",
"name": "P-loop_NTPase",
"type": "HOM... |
ipr_go-000010 | 10 | sha256:ad2ea907ea45035c9658ce71d6525af775e5e2cb247a1245bff85cb9dce29966 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more AAA+_ATPase, ABC_transporter-like_ATP-bd, DrrA1-3-like_C, ABC_transporter-like_ATP-bd that are essential for its biological function; 2. The protein should belong to ABC_transporter... | MNTQPTRAIETSGLVKVYNGTRAVDGLDLDVPAGLVYGILGPNGAGKSTTIRMLATLLRPDGGTARVFGHDVTSEPDTVRRRISVTGQYASVDEGLTGTENLVMMGRLQGYSWARARERAAELIDGFGLGDARDRLLKTYSGGMRRRLDIAASIVVTPDLLFLDEPTTGLDPRSRNQVWDIVRALVDAGTTVLLTTQYLDEADQLADRIAVIDHGRVIAEGTTGELKSSLGSNVLRLRLHDAQSRAEAERLLSAELGVTIHRDSDPTALSARIDDPRQGMRALAELSRTQLEVRSFSLGQSSLDEVFLALTGHPADDRST... | 330 | [
{
"id": "GO:0005524",
"name": "ATP binding "
},
{
"id": "GO:0016887",
"name": " ATP hydrolysis activity "
}
] | [
{
"id": "IPR027417",
"name": "P-loop_NTPase",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 1,
"end": 261
},
{
"id": "IPR003593",
"name": "AAA+_ATPase",
"type": "DOMAIN",
"begin": 33,
"end": 216
},
{
"id": "IPR017871",
"name": "ABC_transporter-like_CS",
"type... |
ipr_go-000011 | 11 | sha256:f295ddc7682b2e3ff4f82ab0bccabeb67219f9e6c0ec6a5255a9bb834282ad29 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more FAD-dep_OxRdtase that are essential for its biological function; 2. The protein should be classified within FAD/NAD-bd_sf, FAD/NAD-bd_sf sharing conserved structural features; 3. Th... | MLRYRQVVGLLQRRNFSAGATSNGSGSSGGDKSGEDLHPIRRTLRLLGNDMRKVKEFFVPKEPETEKVPIPTQSQFHFSGERDKSKEATVPDDFQTHCDVLIIGGGGVGSSIAYWLKEKARDGLNVVVVEKDDTYAQSATRVSVGGLCQQFSLPENIQMSLFAADFLRSARKHFGEEVPLQFTPHGHLMLAGEEHAESLKRSSQLQNELGARNELLTADRLTARFPWLNTKGIALGCLGLEKEGWFNPLALLSNFRRSASGYGAHFISGQVVDFEFKSQTDISVVTDLGSNEGAYTGLEKAVIQLPDGTRRTCKFALCVI... | 515 | [
{
"id": "GO:0016491",
"name": "oxidoreductase activity "
}
] | [
{
"id": "IPR006076",
"name": "FAD-dep_OxRdtase",
"type": "DOMAIN",
"begin": 99,
"end": 482
},
{
"id": "IPR036188",
"name": "FAD/NAD-bd_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 99,
"end": 485
},
{
"id": "IPR036188",
"name": "FAD/NAD-bd_sf",
"type": "... |
ipr_go-000012 | 12 | sha256:6bd107edc9e34f66f2c22eae9672febecece9154557d102db3fa92c074ab48db | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more HCY_dom, HCY_dom that are essential for its biological function; 2. The protein should belong to Hcy_S-methyltransferase, Betaine-hCys_S-MeTrfase_BHMT, Betaine-hCys_S-MeTrfase_BHMT ... | MEVNQKWNWDTKPILVKCGGFSSQLAKNVTEKVDGDPLWGSRFDATNPEAVIQTHLDFLRNGADIILTNTYQSSVEGFVKYLGVTRERGVELIQKSVQLAKQAKEQYLSEIGSEAESALPLIMGSIGPYGAYLHDGSEYTGNYADKMSKEELRAWHKTRIEICLAAGVDGLALETLPCLMEAEAVTELVLDNFPDAKFWVSLQCMDEKHMASGENFAEAALSLWRLVQSRKAENRLLGIGLNCVNPLFVTPLLSSLTKVAGSDRIPLVVYSNRGEIYDVEQGDWTGTGEEVVKFVPEWIQLGVRIVGGCCRVYPTDVLAI... | 331 | [
{
"id": "GO:0047150",
"name": "betaine-homocysteine S-methyltransferase activity "
},
{
"id": "GO:0008898",
"name": " S-adenosylmethionine-homocysteine S-methyltransferase activity "
},
{
"id": "GO:0061627",
"name": " S-methylmethionine-homocysteine S-methyltransferase activity "
}... | [
{
"id": "IPR051486",
"name": "Hcy_S-methyltransferase",
"type": "FAMILY",
"begin": 16,
"end": 324
},
{
"id": "IPR036589",
"name": "HCY_dom_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 11,
"end": 327
},
{
"id": "IPR003726",
"name": "HCY_dom",
"type": "DO... |
ipr_go-000013 | 13 | sha256:cddc21a9c206b5acd72edec11188af523bc79531b47d6d0f42dae01cf0b2c4cc | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to HobA that shares evolutionary origin and functional similarity; 2. The protein should be classified within HobA_sf sharing conserved structural features; 3. The protein must be able to perfor... | MKNFYDWIKEFVRDQGEFIAQQSGWLELERSSYAKLIAQTISHVLNGGSLLVSADSSRHWFLNYILSNLNPKDLKERPLLSVIDFNASSFYPKNDANLSLATIEMTYQNPMFWHVGKIENEGLKTILLSKIPSFLWLFEELKEDCLLLKEHDSLLDYKLLQLFKLFENALFSVLYNKVTL | 180 | [
{
"id": "GO:0042802",
"name": "identical protein binding "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
}
] | [
{
"id": "IPR038381",
"name": "HobA_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 1,
"end": 180
},
{
"id": "IPR021011",
"name": "HobA",
"type": "FAMILY",
"begin": 1,
"end": 180
}
] |
ipr_go-000014 | 14 | sha256:0af3073a7c236a71413178dc89485593fd423e6ef4fe0e3dbe801a5e5e561220 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Elp3/MiaA/NifB-like_rSAM, rSAM, Cobalamin-bd, rSAM, rSAM that are essential for its biological function; 2. The protein should belong to OxsB-like, Tetrapyrrole_Bchl_Biosynth_MTs th... | MQTYLSTKSIEYYLKELKEIFSQIWLKPSEIEKRCEELFKRSKEFDYKRILVSGETDNTTLYVIEDSSKIHVFSPNRDLRENPLLMRWHPSWYEIESKEIYYKCFLSCEELYEHLELPTVTLVNLCVIENFPIPRLNLSTGTLSSYLRKEQLAKVELIDMQVGTTINQIIKNLLDSQPDIIGLSVNFGQKKLAFEILDLIYSHIENGDLSSIITVGNVIPSFSPEQFFERYPSLLICDKEGEYTLRDLIKMLKKELKLDEVNGISYVDESGEVKHNVAETVNFKEEVPTPSLDILGEISKFRGALTLETSRGCDYSRCTF... | 744 | [
{
"id": "GO:0051539",
"name": "4 iron, 4 sulfur cluster binding "
},
{
"id": "GO:0031419",
"name": " cobalamin binding "
},
{
"id": "GO:0016853",
"name": " isomerase activity "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
}
] | [
{
"id": "IPR006638",
"name": "Elp3/MiaA/NifB-like_rSAM",
"type": "DOMAIN",
"begin": 303,
"end": 529
},
{
"id": "IPR007197",
"name": "rSAM",
"type": "DOMAIN",
"begin": 299,
"end": 545
},
{
"id": "IPR023404",
"name": "rSAM_horseshoe",
"type": "HOMOLOGOUS_SUP... |
ipr_go-000015 | 15 | sha256:cc417e15ac0354c49fef7a10ef2eaa3595a3619ba1429df8c3467cd7ce1b7a72 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more HD/PDEase_dom, HD/PDEase_dom that are essential for its biological function; 2. The protein must be able to perform the hydrolase activity , metal ion binding required for its acti... | MSSLLDIIYQLRQVPRWDGSFQFEKEDVSQHSFSVIAISHILCELKETLEGKKINKEKLLLYALYHDVTEVVSTHIISPVKKNSILKDPFNAFREQIKNSLFDNLPITLSDTLSTILNNNDLEIQEIVEHADHVDAYCKSCIEVHRGNKDFISIQRSLGDKLDNLTKEYPYLKEFQNLFLKDFPLENKNYRYLN | 194 | [
{
"id": "GO:0016787",
"name": "hydrolase activity "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
}
] | [
{
"id": "IPR003607",
"name": "HD/PDEase_dom",
"type": "DOMAIN",
"begin": 26,
"end": 94
},
{
"id": "IPR003607",
"name": "HD/PDEase_dom",
"type": "DOMAIN",
"begin": 24,
"end": 146
}
] |
ipr_go-000016 | 16 | sha256:1621eedefff3630c8192cd5b4fcfd4879e875f8fbc8942b921307bce32788e81 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more HTH_TetR, HTH_TetR, HTH_TetR, DesT_TetR_C, HTH_TetR that are essential for its biological function; 2. The protein should belong to HTH-type_TetR-like_transc_reg that shares evoluti... | MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASDVFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVSGVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFENDFVTEPEVAAQVRVATESCIDAVFALISADSGLDPHRARMIAVGLVGMSVDCARYWLDADKPISKSDAVEGTVQFAWGGLSHVPLTRS | 228 | [
{
"id": "GO:0003700",
"name": "DNA-binding transcription factor activity "
},
{
"id": "GO:0000976",
"name": " transcription cis-regulatory region binding "
}
] | [
{
"id": "IPR050109",
"name": "HTH-type_TetR-like_transc_reg",
"type": "FAMILY",
"begin": 27,
"end": 224
},
{
"id": "IPR001647",
"name": "HTH_TetR",
"type": "DOMAIN",
"begin": 44,
"end": 90
},
{
"id": "IPR001647",
"name": "HTH_TetR",
"type": "DOMAIN",
"... |
ipr_go-000017 | 17 | sha256:0e3a88e10bc9db802cafcf77a32ab155d7b9003c45924dd5d25ec8dc07d86905 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GH10_dom, GH10_dom, GH10_dom, GH10_dom, GH10_dom, GH10_dom, GH10_dom that are essential for its biological function; 2. The protein should belong to GH10 that shares evolutionary or... | MRFSASLLLALTGSAAASPIRAEEEIRVYDLPISLFDDLQGLDAAMKAAGREYIGTSLTVRNDFQEQNIIRTEFGSITPENAQKWDATEPNRGQFTFGSADQHMDWARQNGKHVRCHTLVWYSQLPGWVSNSGFNNATLQQVMQNHINQVMGRYRGRCNHWDVVNEAPRLMAMRLQIGEAYIPIAFRMAAQADPSAKLYYNDYNLEYLGPKVEGAARIVRLVKQYGARIDGVGYQAHLVTEPTPTQSTPTPSEEDLIKALRITADLGVDVAYTEIDIRMRTPSNAQKLQQLADAYYRVARSCMKVPRCVGMTIWGVTDRY... | 358 | [
{
"id": "GO:0031176",
"name": "endo-1,4-beta-xylanase activity "
}
] | [
{
"id": "IPR001000",
"name": "GH10_dom",
"type": "DOMAIN",
"begin": 42,
"end": 349
},
{
"id": "IPR001000",
"name": "GH10_dom",
"type": "DOMAIN",
"begin": 225,
"end": 237
},
{
"id": "IPR001000",
"name": "GH10_dom",
"type": "DOMAIN",
"begin": 158,
"e... |
ipr_go-000018 | 18 | sha256:099e0d9d31b95aad01d9114eec635a5ba258509622920c5ebd279553304abc33 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GH10_dom, GH10_dom, GH10_dom, GH10_dom, GH10_dom, GH10_dom, GH10_dom that are essential for its biological function; 2. The protein should belong to GH10 that shares evolutionary or... | MHLASSLFLLATLPFGFAAGKGKGKGKDNSDVGLDVLAKKAGLKYFGAATDTPGQRERAGLEDKYPEYDRIMWHSPEFGSTTPTNGQKWLFVEPERGVFNFTEGDVVASKARQHGKLLRCHALVWHSQLAPWVEETEWTPEELRKVIVDHITAVAGHYKGQCYAWDVVNEALNEDGTYRESVFYKVLGEEYIKLAFETAAKVDPKAKLYYNDYNLEWPSAKTEGAKRIVKLLKDAKIPIHGVGLQAHLIAEQHPTLDDHIAAIRGFTQLGVEVALTELDIRLKTPATEENLALQREAYKNVVGACVQVCGCVGVTIWDFY... | 376 | [
{
"id": "GO:0031176",
"name": "endo-1,4-beta-xylanase activity "
}
] | [
{
"id": "IPR001000",
"name": "GH10_dom",
"type": "DOMAIN",
"begin": 35,
"end": 355
},
{
"id": "IPR044846",
"name": "GH10",
"type": "FAMILY",
"begin": 73,
"end": 320
},
{
"id": "IPR001000",
"name": "GH10_dom",
"type": "DOMAIN",
"begin": 235,
"end": ... |
ipr_go-000019 | 19 | sha256:1c8664061e849fad663355cf9160457527204ce7ad6cf995f8c64f1f58ff76bd | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GH10_dom, GH10_dom, GH10_dom, GH10_dom, GH10_dom, GH10_dom, GH10_dom, Cellulose-bd_dom_fun, Cellulose-bd_dom_fun, Cellulose-bd_dom_fun, Cellulose-bd_dom_fun that are essential for i... | MRSIALALAAAPAVLAQSQLWGQCGGIGWNGPTTCVSGATCTKINDWYHQCLPGGNNNNPPPATTSQWTPPPAQTSSNPPPNNGGGGGNTLHEKFKARGKQYFGTEIDHYHLNNNQLMEIARREFGQITHENSMKWDATEPSRGSFSFGNADRVVDWATSNGKLIRGHTLLWHSQLPQWVQNINDRNTLTQVIENHVKTIMTRYKGKIFHYDVVNEILDENGGLRNSVFSRVLGEDFVGIAFRAARATDPDAKLYINDYNLDSANYAKTRGMINLVNKWVSQGVPIDGIGTQAHLAGPGGWNPASGVPAALQALAGANVK... | 390 | [
{
"id": "GO:0030248",
"name": "cellulose binding "
},
{
"id": "GO:0031176",
"name": " endo-1,4-beta-xylanase activity "
}
] | [
{
"id": "IPR001000",
"name": "GH10_dom",
"type": "DOMAIN",
"begin": 91,
"end": 388
},
{
"id": "IPR017853",
"name": "Glycoside_hydrolase_SF",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 94,
"end": 390
},
{
"id": "IPR001000",
"name": "GH10_dom",
"type": "DOMA... |
ipr_go-000020 | 20 | sha256:b7967041b35792185c1644d9b504fb694f8ba3684cfea21d3146e4216c733f75 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to HAD_2, HAD-like_hydrolase_sf, HAD-SF_hydro_IA, HAD-SF_hydro_IA, HAD-SF_hydro_IA, HAD-SF_hydro_IA, HAD-SF_hydro_IA that shares evolutionary origin and functional similarity; 2. The protein sho... | MKPLVIFDLDGTLVDTPSGIVSAFITALRDLSMPFEDRRAIRATIGLPLEKAFGQILALPVEDERVTAAVRQYQAVFREQVLPQAPGLVFPGVVEGLALLKGQGYTLAVATSKVFASAKALLEAAGLWSYFDLVLGADMVAHPKPHPEMGLLAMSRLGADAATTAMVGDTTHDLLMAKQAGMAAIGVTWGIHTTDQLKAAEPQVIVDTFSEVVGAAHALLKLSSSPVSYC | 230 | [
{
"id": "GO:0046872",
"name": "metal ion binding "
},
{
"id": "GO:0008967",
"name": " phosphoglycolate phosphatase activity "
}
] | [
{
"id": "IPR036412",
"name": "HAD-like_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 2,
"end": 214
},
{
"id": "IPR041492",
"name": "HAD_2",
"type": "FAMILY",
"begin": 5,
"end": 187
},
{
"id": "IPR050155",
"name": "HAD-like_hydrolase_sf",
"type": "FAMILY"... |
ipr_go-000021 | 21 | sha256:e807cc0f18dab0c8533953590ec89f24222d44a8b0e1f52a2c74b876a731b693 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more CEP76_C, CEPT76/DRC7_peptidase-like_dom, C2_dom, C2_dom, C2_dom, C2_dom that are essential for its biological function; 2. The protein should belong to CEP76 that shares evolutionar... | MILDKFKNIVNLSNSNTEKEEGKNAEINENNDPNTQLAHEPSIVEADEKTFFDEMLGAPQYTYDEFLQVLKNPIEERGDTEDMKKHWGYPRRWKVILWDLHIQNYMNNDFNAFVDFDFGGNREECRIQRGSTMKIYAKGKTKNCLRTPVVTNVATEQKKNMNFRNVFEYRGSYLDLENEKLRIRVWEYKQFTLNKLEGIYEEPLLSFAVGEIYNETTLYKFIKDSRVKRCRLYFQLYFQELYDFELSFLNWSFSDLLSSSYIQAKSYNYLSNKNNVKKRYIDDTSCNIFPHMCKNFKRFHKKKIYRKVRNYDIDKNFSFN... | 1,846 | [
{
"id": "GO:0005544",
"name": "calcium-dependent phospholipid binding "
}
] | [
{
"id": "IPR052299",
"name": "CEP76",
"type": "FAMILY",
"begin": 9,
"end": 1120
},
{
"id": "IPR056288",
"name": "CEP76_C",
"type": "DOMAIN",
"begin": 989,
"end": 1126
},
{
"id": "IPR035892",
"name": "C2_domain_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"be... |
ipr_go-000022 | 22 | sha256:efad9c6b7776bbc78e56d40d80cd2f860218a2783d4d092d0f3250c6908ee57c | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more TmcA_N, NAT10/TcmA_helicase, GNAT_dom, GNAT_dom that are essential for its biological function; 2. The protein should belong to tRNA_acetyltr_TmcA, TmcA/NAT10/Kre33 that shares evol... | MTVKVKFPKDIREYARKEKVKDSLIKLTETALAEAISKFHRRMIVLQGDTLNKAKLAGILAGGAARILSEYIPEMLERKLRDTEQIEVLYATDALGEDTYGRKRFEEFRKHFSLLAPTAELTSVTFKHSRDILGRTFDILVIDLSYDYSPNDLGRIIETVRGGGLIFVLTNPFEKWKDMWTGFHKSLVTPPYTIEDVKKRFNRRLIRKFTEHKGIYIVNTDRMSIERKPGKYRSQATLPEREKVEIPKNIRFPRELYELCLTRGQVEVLKTLEELIEKEGMVVLTADRGRGKSVSIGIASVGLAVSSKKKRFRIVVTAPE... | 816 | [
{
"id": "GO:1990883",
"name": "18S rRNA cytidine N-acetyltransferase activity "
},
{
"id": "GO:0005524",
"name": " ATP binding "
},
{
"id": "GO:0004386",
"name": " helicase activity "
},
{
"id": "GO:0016787",
"name": " hydrolase activity "
},
{
"id": "GO:0106162",... | [
{
"id": "IPR013562",
"name": "TmcA_N",
"type": "DOMAIN",
"begin": 28,
"end": 219
},
{
"id": "IPR027417",
"name": "P-loop_NTPase",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 279,
"end": 447
},
{
"id": "IPR024914",
"name": "tRNA_acetyltr_TmcA",
"type": "FAMI... |
ipr_go-000023 | 23 | sha256:6e283cc779810dd9174f1b61924b8c74d0bd81ae7161f1184006352195efc500 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GH11_dom, GH11_dom that are essential for its biological function; 2. The protein should belong to Glyco_hydro_11, Glyco_hydro_11, Glyco_hydro_11, Glyco_hydro_11, Glyco_hydro_11, Gl... | MVSFTTLLTAVATAVSAVTASPLEALKRGIQPGTGVHDGYFYSFWTDGRGYVDFNNGPRGSYRVSWSNVNNWVGGKGWNPGPPRRIAYNGTWNNWNVNSYLALYGWTTNPLVEYYIVEAYGSYNPSSGAARLGTIEDDGGVYDIYRTRRINQPSIIGTASFDQYWSVRRQKRVGGTIDTGKHFDEWRRQGNLQLGAWNYMIMATEGYQSSGSAEIEVRSLD | 221 | [
{
"id": "GO:0031176",
"name": "endo-1,4-beta-xylanase activity "
}
] | [
{
"id": "IPR001137",
"name": "Glyco_hydro_11",
"type": "FAMILY",
"begin": 158,
"end": 163
},
{
"id": "IPR001137",
"name": "Glyco_hydro_11",
"type": "FAMILY",
"begin": 138,
"end": 144
},
{
"id": "IPR001137",
"name": "Glyco_hydro_11",
"type": "FAMILY",
"... |
ipr_go-000024 | 24 | sha256:50d3469575943c69659937ec94d1f84b72a59b8d874475defb7b29759a02ee84 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Glyco_hydro_43, Glycosyl_Hydrlase_43_Enz that shares evolutionary origin and functional similarity; 2. The protein should be classified within Glyco_hydro_beta-prop_sf, Glyco_hydro_beta-prop_... | MAPLITNIYTADPSAHVFNGKLYIYPSHDRETDIQFNDNGDQYDMADYHVFSLDSLDPPSEVTDHGVVLKVEDIPWVSKQLWAPDAATKDGKYYLYFPARDKEGIFRIGVAVSDKPEGPFTPDPEPIKGSYSIDPAVFVDDDGSAYMYFGGLWGGQLQCYQKGNNIFDAEWSGPKEPSGSGAKALGPRVAKLTDDMRQFAEEVREIVILAPETGEPLAADDHDRRFFEAAWMHKYNGKYYFSYSTGDTHYLVYAVGDSPYGPFTYGGRILEPVLGWTTHHSIVEFQGRWWLFHHDCELSKGVDHLRSVKVKEIWYDKDGK... | 327 | [
{
"id": "GO:0009044",
"name": "xylan 1,4-beta-xylosidase activity "
}
] | [
{
"id": "IPR006710",
"name": "Glyco_hydro_43",
"type": "FAMILY",
"begin": 65,
"end": 320
},
{
"id": "IPR052176",
"name": "Glycosyl_Hydrlase_43_Enz",
"type": "FAMILY",
"begin": 3,
"end": 326
},
{
"id": "IPR023296",
"name": "Glyco_hydro_beta-prop_sf",
"type"... |
ipr_go-000025 | 25 | sha256:c5cf3682979f916b743dae9d58b015b87b664ef42086c83e4f9416f69c814f7f | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Ser/Thr-sp_prot-phosphatase, Ser/Thr-sp_prot-phosphatase, PPP_dom, PP5_C, Ser/Thr-sp_prot-phosphatase, Ser/Thr-sp_prot-phosphatase, Ser/Thr-sp_prot-phosphatase, Ser/Thr-sp_prot-phos... | MASSDLEAATALKVQGNKAFGQHEWPTAVDFYTQAIAKYDREPSFFSNRAQAHIKLEAYGFAIADATKALELDPAYTKAYWRRALANTAILNYKDALRDFKVVAKREPNNRDAKVKLADCEKLVRRMEFEKAIEVGDPPSAFEDLDIDAIAVDDSYDGVRLEKEMTQEFIDDMIERFKNGKKIHRKYAFQIVKAVKDIVYAEPTMVEIGVDQGTKLTVCGDTHGQFFDLLEIFRLNGYPSEKHAYLFNGDFVDRGSWSTEIALLLYAYKWLRPNGIFLNRGNHETDDMNKVYGFEGECKAKYNERMFKVFSESFSALPLA... | 478 | [
{
"id": "GO:0046872",
"name": "metal ion binding "
},
{
"id": "GO:0016791",
"name": " phosphatase activity "
},
{
"id": "GO:0004722",
"name": " protein serine/threonine phosphatase activity "
}
] | [
{
"id": "IPR051134",
"name": "PPP_phosphatase",
"type": "FAMILY",
"begin": 45,
"end": 473
},
{
"id": "IPR006186",
"name": "Ser/Thr-sp_prot-phosphatase",
"type": "DOMAIN",
"begin": 279,
"end": 284
},
{
"id": "IPR006186",
"name": "Ser/Thr-sp_prot-phosphatase",
... |
ipr_go-000026 | 26 | sha256:b0dc5e50b16fe4fb37e0a6977ac17dd94f31021f79855fd06739f1865d49b609 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more DnaA_C, DnaA_dom, DnaA_N_dom, AAA+_ATPase, DnaA_C, DnaA_C that are essential for its biological function; 2. The protein should belong to Chromosome_initiator_DnaA, Chromosome_initi... | MRRGKKVGGIVLIPYSAAIAVEQSLEHLWEQILERLQHQLSRPTFETWIKTATAEAFDGKVLRLSTPNPFARNWLQKYYLRTIADVAAEILGHGIELQIGVLSDTSAEPESGAELWPAISPPPAVEVVKPPTTTAGRPPLRSSDLNPKYVFSRFVVGANNRMAHAASLAIAEYPGREYNPLFLCGGVGLGKTHLMQAIGHYRLEIDPDAKIFYVSTEQFTNDLIAAIRRDSMQSFREHYRAADVIMVDDIQFIEGKEYTQEEFFYTFNSLHEAGKQIVLASDRPPSQIPRLQERLISRFSMGLIADIQPPDFETRVAILQ... | 482 | [
{
"id": "GO:0005524",
"name": "ATP binding "
},
{
"id": "GO:0016887",
"name": " ATP hydrolysis activity "
},
{
"id": "GO:0003688",
"name": " DNA replication origin binding "
},
{
"id": "GO:0008289",
"name": " lipid binding "
}
] | [
{
"id": "IPR013159",
"name": "DnaA_C",
"type": "DOMAIN",
"begin": 387,
"end": 476
},
{
"id": "IPR001957",
"name": "Chromosome_initiator_DnaA",
"type": "FAMILY",
"begin": 29,
"end": 476
},
{
"id": "IPR013317",
"name": "DnaA_dom",
"type": "DOMAIN",
"begi... |
ipr_go-000027 | 27 | sha256:729a48d70d6bbe461cee74d78aec69eadd0836a65bfc944cb3241dac87281b34 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to CrtA-like that shares evolutionary origin and functional similarity; 2. The protein must be able to perform the metal ion binding , spheroidene monooxygenase activity required for its activi... | MQTVTLSIFRFNEFEKRLWVLGQMTANKLGMHYLPKAKFWKMFGSGTGQGFTPKPNWHVWSILAVWPDEETARREVAESPIYQRWTKMADESYTVLLQPTSAWGKWDGKEPFEPVKPASDVRPIAALTRATVKFWKAERFWAREPAISHMIGRNKDVVFKIGVGEVPFVQQVTFSIWPDARSMEEFARGAGGPHGEAIKAVRAENWFKEELYARFQILGTIGKWEGKDPVGEALTARPSEAPKPAPAPAAAQPAPAAEAPKPAPAPVAEKPALAVEMPKPAEPPKPVVEAPKPASAPVASKPMPQGGKPNFKGKPGKGGR... | 324 | [
{
"id": "GO:0046872",
"name": "metal ion binding "
},
{
"id": "GO:0043823",
"name": " spheroidene monooxygenase activity "
}
] | [
{
"id": "IPR049574",
"name": "CrtA-like",
"type": "FAMILY",
"begin": 3,
"end": 228
}
] |
ipr_go-000028 | 28 | sha256:988a45b94bdf9854fe2938f5dca65ebc73a07414f1d018dcbbc91c52ce85ad8a | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to MgTranspt_CorA/ZnTranspt_ZntB that shares evolutionary origin and functional similarity; 2. The protein should be classified within CorA_cytoplasmic_dom, CorA_TM1_TM2 sharing conserved struct... | MQAYESGDERGLIYGYVLNGRGGGRRVGRNQIAVLDLLPEESLWLHWDRGVPEAQAWLRDSAGLSEFACDLLLEEATRPRLLDLGAESLLVFLRGVNLNPGAEPEDMVSLRVFADARRVISLRLRPLKAVADLLEDLEAGKGPKTASEVVYYLAHYLTDRVDTLISGIADQLDAVEELVEADERASPDQHQLRTLRRRSAGLRRYLAPQRDIYSQLARYKLSWFVEDDADYWNELNNRLTRNLEELELIRERISVLQEAESRRITERMNRTMYLLGIITGFFLPMSFVTGLLGINVGGIPGADAPHGFWLACLLIGGVAT... | 332 | [
{
"id": "GO:0046873",
"name": "metal ion transmembrane transporter activity "
}
] | [
{
"id": "IPR045861",
"name": "CorA_cytoplasmic_dom",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 9,
"end": 260
},
{
"id": "IPR002523",
"name": "MgTranspt_CorA/ZnTranspt_ZntB",
"type": "FAMILY",
"begin": 41,
"end": 328
},
{
"id": "IPR045863",
"name": "CorA_TM1_T... |
ipr_go-000029 | 29 | sha256:701f68cbfc318376cdacc20fdf60c419cad69fc3e7e52cfd4cca8b47e5aca46e | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Ketoacyl_synth_N, PP-bd_ACP, PKS_DH, Acyl_transferase_dom, ADH-like_C, PKS_mFAS_DH, Acyl_transferase_dom, Ketoacyl_synth_C, PKS_ER, PKS_DH_C, PKS_Beta-ketoAc_synthase_dom, Methyltra... | MQSAGMHRATAEPIAIVGLSCKFAGEASTPDRLWEMLAAGRSAWSEIPPSRFNLKGAYHPSADRTNTVCFNSLCRGNPTEEKKVHVRGGHFLEQDLGLFDAQFFSFSAETAASMDPQIRLQLESVYEALENAGITLPDVAGSNTAVYAAVFSRDYRDGIIRDEDRLPRFLPTGTGDAMFSNRVSHFFDLRGPSITLDTGCSGGLVALHEGVKSLRTGESDMALISGEGLTDEGRFFSPDGKSYAFDSRANGYGRGEGIATIVIKRLSDAIIAGDPIRAIVRESGLNQDGKTETITTPSEEAQVALMRDCYRRAGLDYADT... | 2,568 | [
{
"id": "GO:0004312",
"name": "fatty acid synthase activity "
},
{
"id": "GO:0008168",
"name": " methyltransferase activity "
},
{
"id": "GO:0016491",
"name": " oxidoreductase activity "
},
{
"id": "GO:0031177",
"name": " phosphopantetheine binding "
},
{
"id": "G... | [
{
"id": "IPR014030",
"name": "Ketoacyl_synth_N",
"type": "DOMAIN",
"begin": 12,
"end": 269
},
{
"id": "IPR036291",
"name": "NAD(P)-bd_dom_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 1959,
"end": 2126
},
{
"id": "IPR009081",
"name": "PP-bd_ACP",
"type":... |
ipr_go-000030 | 30 | sha256:c0a362a3050d93d98be75f3ac1029e6c8fd68639ca3f45c8eda8bc47cee0a113 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Ribosomal_eL44, Ribosomal_eL44, Ribosomal_eL44, Ribosomal_eL44 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Ribosomal_zn-bd, Ribosomal... | MKYPKQIRTYCPFCKRHTIHKVEKVKKRPRSELSAGQRRFRRKLKGYTGFPRPNPAGREKPVKKLDLRFRCTVCGKAHTRGQGFRVKKFELVEV | 94 | [
{
"id": "GO:0070180",
"name": "large ribosomal subunit rRNA binding "
},
{
"id": "GO:0003735",
"name": " structural constituent of ribosome "
},
{
"id": "GO:0008270",
"name": " zinc ion binding "
}
] | [
{
"id": "IPR000552",
"name": "Ribosomal_eL44",
"type": "FAMILY",
"begin": 2,
"end": 92
},
{
"id": "IPR000552",
"name": "Ribosomal_eL44",
"type": "FAMILY",
"begin": 16,
"end": 92
},
{
"id": "IPR011332",
"name": "Ribosomal_zn-bd",
"type": "HOMOLOGOUS_SUPERFA... |
ipr_go-000031 | 31 | sha256:6872668a1169d79c41e0e3217c7a0afaf399201ad1db1edc0cc760ca366b5635 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to BT1, BT1 that shares evolutionary origin and functional similarity; 2. The protein should be classified within MFS_trans_sf, MFS_trans_sf sharing conserved structural features; 3. The protein... | MIEKSNNPFLSIDPIVERTKSNGEGLPLLSEKTKKGFDFTQIVVYLVGLSDGLTHLASLAIYYLFKDYFRLTPYQVSLILMYPYIPFILKPVIALITDSFSIFGMRRKPYLFLFSLFQSLNFLALAFLNLSVIQASLILFFISLCASFCTTVAEALVVESSMGQTYSQGTNKVTEFIASKAIGSLSVAYFSGYFLEKMPREYIFIATSIFPLIISLSCLFLKEKEYSTNRNIFNQLSDLIKFINTPIFLGPFLYIFVYMSGPDYDDAFFFFCTNKLGFRPSFMGTLRLTYGIASLIGIIIYRVFLKNCSLRKTLIITTLV... | 455 | [
{
"id": "GO:0008517",
"name": "folic acid transmembrane transporter activity "
}
] | [
{
"id": "IPR036259",
"name": "MFS_trans_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 42,
"end": 231
},
{
"id": "IPR036259",
"name": "MFS_trans_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 50,
"end": 443
},
{
"id": "IPR039309",
"name": "BT1",
"type": ... |
ipr_go-000032 | 32 | sha256:fd07dbf9bfb5cb23c30118d25ae54d0b10bd6ce7e6599f4edef4712571d4789e | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Ribosomal_eL19_dom, Ribosomal_eL19_dom, Ribosomal_eL19_dom that are essential for its biological function; 2. The protein should belong to Ribosomal_eL19 that shares evolutionary or... | MIMLKTQRRIAAELLKCGENRIWIDPERIEDVAAAITREDIKRLIHDGVIKKKPIKGQSRARARAFQEARKKGRHRGPGSKKGKKTARMGKKEVWMMTIRALRKELRKLKAEGKLDAHTYRRLYIRAKGGQFKNKRQLYMFMQEHGILKE | 150 | [
{
"id": "GO:0070180",
"name": "large ribosomal subunit rRNA binding "
},
{
"id": "GO:0003723",
"name": " RNA binding "
},
{
"id": "GO:0003735",
"name": " structural constituent of ribosome "
}
] | [
{
"id": "IPR023638",
"name": "Ribosomal_eL19_CS",
"type": "CONSERVED_SITE",
"begin": 7,
"end": 26
},
{
"id": "IPR039547",
"name": "Ribosomal_eL19",
"type": "FAMILY",
"begin": 1,
"end": 143
},
{
"id": "IPR035970",
"name": "60S_ribosomal_eL19_sf",
"type": "H... |
ipr_go-000033 | 33 | sha256:bd1ae21d4d6b2155ee292802de80ed9a0a9be76bd414045d979fdca2cb4a9e30 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GPCR_Rhodpsn_7TM that are essential for its biological function; 2. The protein should belong to Olfact_rcpt, Olfact_rcpt, Olfact_rcpt, Olfact_rcpt, Olfact_rcpt, GPCR_Rhodpsn, GPCR_... | MVNFTHVSEFVLLGFQGGPGMQAMLFLIFLILYGIAVVGNLGMIVIIWVDAHLHTPMYAFLQSLSLLDICYSSTIAPRALANSMQEDHTISFGGCAAQFFFLSLFGITEAFLLAAMAYDRFIAICNPLLYSVSMSHQVCVLLISGSYLWGVVNAIAQTTMTFRLPFCGSNEINDFFCDVPPLLSLSCSDTFINQLVLLGLCGSIIVSTFLIVLVSYIYIISTILRIPTMQGCQKAFSTCASHLTGVCLFFGTVFFMYAQPSAIFFMEQSKIVSIFYTMVIPMLNPLIYSLRNKEVKQALRRSMQKLSL | 308 | [
{
"id": "GO:0004930",
"name": "G protein-coupled receptor activity "
},
{
"id": "GO:0004984",
"name": " olfactory receptor activity "
}
] | [
{
"id": "IPR000725",
"name": "Olfact_rcpt",
"type": "FAMILY",
"begin": 234,
"end": 243
},
{
"id": "IPR000725",
"name": "Olfact_rcpt",
"type": "FAMILY",
"begin": 90,
"end": 101
},
{
"id": "IPR000725",
"name": "Olfact_rcpt",
"type": "FAMILY",
"begin": 12... |
ipr_go-000034 | 34 | sha256:79ec54a1b9a163f1fff48088a706f31d4fafb5f1834f53349d86da2f5110f685 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to PsuG, PsuG that shares evolutionary origin and functional similarity; 2. The protein should be classified within Indigdn_synthA-like, Indigdn_synthA-like sharing conserved structural features... | MSKTDFSHDLLRFSDEVKEALHSGKPVVALESTVIAHGLPYPENVATARKIEAAVRAEGAIPATIGIENGRFLIGMSDADLERFGSTRGIPKASSRDIPVILAQGGMGATTVASSLVAADLAGIPFFASAGIGGVHRGAERSMDISADLIQFTRSRVAVVCAGAKSILDLGLTLEYLETQCVPIISYQSDDFPAFYCRSSGFHSPHRLDDATVIARSIDMHWKLGNQSSVLITHPIHEEDAIGTDEVESIIREAAVQAEHEGIRGPGATPYLMRAVAKATEGKTVKANMSVLISTAALAGKLACAHIDYLRQQNQA | 316 | [
{
"id": "GO:0016798",
"name": "hydrolase activity, acting on glycosyl bonds "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
},
{
"id": "GO:0004730",
"name": " pseudouridylate synthase activity "
}
] | [
{
"id": "IPR007342",
"name": "PsuG",
"type": "FAMILY",
"begin": 16,
"end": 304
},
{
"id": "IPR022830",
"name": "Indigdn_synthA-like",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 6,
"end": 309
},
{
"id": "IPR022830",
"name": "Indigdn_synthA-like",
"type": "H... |
ipr_go-000035 | 35 | sha256:3e683829c8442e0bf03ec13937dea8f96def35b5488452f2558692c05563ba91 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Thioesterase, PP-bd_ACP, PP-bd_ACP, AMP-dep_synth/lig_dom, AA_adenyl_dom, PKS_PP-bd that are essential for its biological function; 2. The protein should be classified within ACP-li... | MDNISNHAFNYPVLVLNKGLLPEHDDIALARYLFSALALAVSRITQNEEMIVGFHLHPQEITRWKDDECIRQYILPLNIRFNSATPIAGFIREIMTWMTPDAIHQKNAMGASVLTLGPQHALHDIFDLEISWQPPVESEPVQALTCHVASREDALVLTLRFNPARFSATQMQKLPEVWRQITASAAKNGAETLRDIGLIDDAERQRVLHAFNQTEQAWDGETTVAARLKNRAQRHPEQTAVVFRDETLSYRQLYQQAGALAHYLNALETERERCVGLFVEPSLTLMTGVWGILLSGNAYLPLSPEYPEDRLAYMLENSQT... | 1,488 | [
{
"id": "GO:0016829",
"name": "lyase activity "
},
{
"id": "GO:0016491",
"name": " oxidoreductase activity "
},
{
"id": "GO:0031177",
"name": " phosphopantetheine binding "
}
] | [
{
"id": "IPR001031",
"name": "Thioesterase",
"type": "DOMAIN",
"begin": 1230,
"end": 1346
},
{
"id": "IPR009081",
"name": "PP-bd_ACP",
"type": "DOMAIN",
"begin": 1145,
"end": 1208
},
{
"id": "IPR009081",
"name": "PP-bd_ACP",
"type": "DOMAIN",
"begin": ... |
ipr_go-000036 | 36 | sha256:4d7ff8f97540a27b3e75118f82df28e82087f33a3652f781a7c4f3611ee726bb | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Phosphatidylglycerol_P_synth, CDP-alcohol_PTase-I, CDP-OH_P_trans that shares evolutionary origin and functional similarity; 2. The protein should be classified within CDP-OH_PTrfase_TM_dom s... | MSIIGSFPPGGPRVEVQETRVQTDRVLTIPNILSMARLAGVPLFLWLILRPEFGGPQSDGWALLVLALSGVSDYLDGKLARRWNQISSLGRLLDPAADRLYILSTLVGLTWREILPLWLTLVLLAREAMLLVMVGILRRHGYPPPQVNFLGKAATFNLMYAFPLLLLSDGSGWIASLAAVFGWAFAGWGTTLYWWAGVLYVVQVRRLVRADVAAD | 215 | [
{
"id": "GO:0043337",
"name": "cardiolipin synthase (CMP-forming) "
},
{
"id": "GO:0008444",
"name": " CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity "
}
] | [
{
"id": "IPR043130",
"name": "CDP-OH_PTrfase_TM_dom",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 23,
"end": 211
},
{
"id": "IPR004570",
"name": "Phosphatidylglycerol_P_synth",
"type": "FAMILY",
"begin": 24,
"end": 215
},
{
"id": "IPR048254",
"name": "CDP_ALCOH... |
ipr_go-000037 | 37 | sha256:51d4c0c4566dd5a453776af928588d79c76090f51f04d3c471c21531287c77f5 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Methyltransf_12 that are essential for its biological function; 2. The protein should belong to MeTrfase_VrtF that shares evolutionary origin and functional similarity; 3. The prote... | MTTTSASTTDHLIDQQVIDGQAGYTKSFLNIYDLAVFKGTAPLAWHCSPAVSRQMYDTCLGANHVEIGVGTGYLLDNATFPVADPKITLVDLNPNSLAHTAQRLNRYDVTTVRANVLEPLPLEERAYDSVGMSYLLHCVPGSIKEKGIALKHAAAVVRPGGVVFGATVLSSGVPVSARGRWTMNYLNKRGDFHNQEDNYDDLRDQLAQYFPRFQLTSRGCVGIWRAWTTD | 230 | [
{
"id": "GO:0008168",
"name": "methyltransferase activity "
}
] | [
{
"id": "IPR029063",
"name": "SAM-dependent_MTases_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 32,
"end": 211
},
{
"id": "IPR016584",
"name": "MeTrfase_VrtF",
"type": "FAMILY",
"begin": 8,
"end": 230
},
{
"id": "IPR013217",
"name": "Methyltransf_12",
"... |
ipr_go-000038 | 38 | sha256:3164fbc4f11b9d95188d1d240b8371851f4562adacc551b564f7e6157797e81d | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Eqnu_transpt, Eqnu_transpt, Eqnu_transpt, Eqnu_transpt, Eqnu_transpt, ENT1/ENT2 that shares evolutionary origin and functional similarity; 2. The protein should be classified within MFS_trans... | MSLKGGTAAPAPMAPPRKWYDMTSAEFYVYVVAFMCGISIMMPINAVFSAPSYMLEYYLYATKDPFLVPKMTNFWTNVMTYYNLISMVTSLVVEPLTLLKSFRKIPMLVRLLGGLSVLIIEIIVLMVVPARGTTEAGAVATMCIAGFIGGLGTSIFESTVYGMFGAFPPSFTSIMMGGVGISGVLTSLIQIIVKAALPDTYEGVKKQSYIYYSLDVGIQAATFIALIMMRFNSFAQLHFGDLGGVKSKVDAGSLAGAGENVREPGAEATELEQYTEPAIGQIQEKNAEAHKDDPLAERELSEEESGDSRAVEAAGEAPTS... | 497 | [
{
"id": "GO:0005337",
"name": "nucleoside transmembrane transporter activity "
}
] | [
{
"id": "IPR002259",
"name": "Eqnu_transpt",
"type": "FAMILY",
"begin": 149,
"end": 171
},
{
"id": "IPR002259",
"name": "Eqnu_transpt",
"type": "FAMILY",
"begin": 468,
"end": 492
},
{
"id": "IPR002259",
"name": "Eqnu_transpt",
"type": "FAMILY",
"begin"... |
ipr_go-000039 | 39 | sha256:de3aa0477e01f80d9d5e22a08b333696491763651bead8cf42b18579b0d8420e | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GNAT_dom, NAT10/TcmA_helicase, TmcA_N, GNAT_dom that are essential for its biological function; 2. The protein should belong to TmcA/NAT10/Kre33, tRNA_acetyltr_TmcA that shares evol... | MIPGSNPGGRIHNVIEMFENYFMDAVKGYYRHLAIIESQDPLEKINSLIDDYLKVNKKPRVIYGFHPWLDNSKDRMKELKKRFENFLDIDYSNSEKYLGQSADLVILDAMDDFRPNYIARFVDMTKGGGIAIIYSDNILEGKLYKKSLTRYGVVKDLFEARFIELAKRYRGIIFFQGNDRITFTPYSSNETHKPYKKIPKSPKVSMELHELCLSSDQNKVLEESLFIMNLGKRVLVITAARGRGKSASIGLFLSYLMSEGNFGSIIVTSPTYYSSQEIFKFIIRGLEALNVKYKVITSRDGKIMKISTRDSRVKWVSPDL... | 743 | [
{
"id": "GO:1990883",
"name": "18S rRNA cytidine N-acetyltransferase activity "
},
{
"id": "GO:0005524",
"name": " ATP binding "
},
{
"id": "GO:0106162",
"name": " mRNA N-acetyltransferase activity "
},
{
"id": "GO:0019843",
"name": " rRNA binding "
},
{
"id": "GO... | [
{
"id": "IPR027417",
"name": "P-loop_NTPase",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 41,
"end": 357
},
{
"id": "IPR032672",
"name": "TmcA/NAT10/Kre33",
"type": "FAMILY",
"begin": 555,
"end": 740
},
{
"id": "IPR000182",
"name": "GNAT_dom",
"type": "DOMA... |
ipr_go-000040 | 40 | sha256:c119806f4af8df36d96a0b3132aa84ccec0f7513a38b42c3ceb1495fb192ffc3 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to BT1, BT1 that shares evolutionary origin and functional similarity; 2. The protein should be classified within MFS_trans_sf, MFS_trans_sf, MFS_trans_sf sharing conserved structural features; ... | MEDDDFSIKDKKENYETCSTETISSYISINEKCQLIEKDINDDNHENPYMIFNKISSSLIAMLQGVEVLCNLSIIYLLKDNYHLHPASLSIVMCFIKIPWSIKLVWAVISDNYPIFGYRRKYYLLLGSFLCILSLICLGLITHNNLFITILLLFIYFFGSSLCNVIGEAQVVESNRNCSINSSARNVSLFFAFRKLSFAIMSYLSGYLLLLISKKHIFLIGSFLPICVFTSGFFIIEKRNYTKSSIKDQIKCIYSIIKLSYLKNFIIFIFIMMSTPSCGNTLFFYITNELKFSPNLLGKMAMFQSLASFISIISYMLFFT... | 505 | [
{
"id": "GO:0008517",
"name": "folic acid transmembrane transporter activity "
}
] | [
{
"id": "IPR036259",
"name": "MFS_trans_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 55,
"end": 248
},
{
"id": "IPR039309",
"name": "BT1",
"type": "FAMILY",
"begin": 58,
"end": 465
},
{
"id": "IPR036259",
"name": "MFS_trans_sf",
"type": "HOMOLOGOUS_SUPE... |
ipr_go-000041 | 41 | sha256:4c8973d7468158c8175a67ed07434d008aaf57307a621aab360cc26d615ada85 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more TmcA_N, GNAT_dom, GNAT_dom, GNAT_dom, NAT10/TcmA_helicase that are essential for its biological function; 2. The protein should belong to tRNA_acetyltr_TmcA, TmcA/NAT10/Kre33 that s... | MVNKEQFYDQIRKALEDGNTRYYRNLIYIERDDYFDHVKEIISLFLNFKSNPSVAYGFVPWASGSKERMRTIKEYFSKFDDIDYANAEYYLGNTYDLVILDTVDNFQPINIGRLVDLARGGGLIIIYTNNLIKDKTFRTSIMRNGLILDEYEKRFKRKLYEHEGIFIIDVNEYIPKPFSGNTMPKAEKKVPRNPLMPKEIHELSLSEDQNRVIESFTYLLSGGQRALVLTAARGRGKSAATGLSIAGLIEKLRERKEKSIRIIVTAPSIASASQVMSFAKLGLEALGEELSVKVSDTGHIKSLRGDYFKLEYVPPDAAIE... | 770 | [
{
"id": "GO:1990883",
"name": "18S rRNA cytidine N-acetyltransferase activity "
},
{
"id": "GO:0005524",
"name": " ATP binding "
},
{
"id": "GO:0106162",
"name": " mRNA N-acetyltransferase activity "
},
{
"id": "GO:0019843",
"name": " rRNA binding "
},
{
"id": "GO... | [
{
"id": "IPR027417",
"name": "P-loop_NTPase",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 225,
"end": 398
},
{
"id": "IPR016181",
"name": "Acyl_CoA_acyltransferase",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 511,
"end": 591
},
{
"id": "IPR027417",
"name": "P-l... |
ipr_go-000042 | 42 | sha256:05d96ad7f89c4b2d79479233554410215049beb269b097bdc3f1d62855a807c4 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more NIF_FeS_clus_asmbl_NifU_N, NIF_FeS_clus_asmbl_NifU_N, NIF_FeS_clus_asmbl_NifU_N that are essential for its biological function; 2. The protein should belong to ISCU that shares evol... | MSLVRNSSRLLRSQLKRVQSVPVALYHENVVEHYENPRNVGSLDKKDVTVGTGLVGAPACGDVMKLQIKVDENGKIVDAKFKTFGCGSAIASSSLATEWVKGKSIDEAGKLKNTDIAKELRLPPVKLHCSMLAEDAIKAALADYKVKQQKKVAN | 154 | [
{
"id": "GO:0051537",
"name": "2 iron, 2 sulfur cluster binding "
},
{
"id": "GO:0008198",
"name": " ferrous iron binding "
},
{
"id": "GO:0140132",
"name": " iron-sulfur cluster chaperone activity "
}
] | [
{
"id": "IPR002871",
"name": "NIF_FeS_clus_asmbl_NifU_N",
"type": "DOMAIN",
"begin": 25,
"end": 140
},
{
"id": "IPR002871",
"name": "NIF_FeS_clus_asmbl_NifU_N",
"type": "DOMAIN",
"begin": 17,
"end": 153
},
{
"id": "IPR002871",
"name": "NIF_FeS_clus_asmbl_NifU_... |
ipr_go-000043 | 43 | sha256:536d54264e6ff3f5d7f7604b6c1376b560b69f4005ef267570182f96dffb6a42 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more AK-Hom3, Asp/Glu/Uridylate_kinase, ACT_Aspartokinase that are essential for its biological function; 2. The protein should belong to Asp_kinase that shares evolutionary origin and f... | MSSASTPTAPYLEDLVRNSLDQNLPWVVQKYGGTSVGKSLDNITKIVGSYIDNGSKVAIVCSARSTQTKSLGTTNLLLQASREALQPAMSSSGDGRSGSMSGTATPFYPKRVGSGFFGKDQSTSMTSSVSSLSQLESQLGRSGSPSPFQSSSSRSPPRSPATPSQDSSISQEPAFHATVDLIKKGHLEAARASLKGGPLRDELEEEIERDCESLRSFLYAAQIIDEISPRSQDSIVGTGERLACKIVAAALRDRGVDSELVVLDNIVDASMSAASEAVSVDAGDQGVAQLGQEFYDQLSFRLGERLRECGQRVPVVTGYF... | 615 | [
{
"id": "GO:0004072",
"name": "aspartate kinase activity "
},
{
"id": "GO:0005524",
"name": " ATP binding "
}
] | [
{
"id": "IPR018042",
"name": "Aspartate_kinase_CS",
"type": "CONSERVED_SITE",
"begin": 28,
"end": 36
},
{
"id": "IPR036393",
"name": "AceGlu_kinase-like_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 26,
"end": 428
},
{
"id": "IPR041747",
"name": "AK-Hom3",
... |
ipr_go-000044 | 44 | sha256:57825f4d67b7b8a868fb283bc084d32ce6202d902a078ce010f45f7dba5b26c0 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more AB_hydrolase_1 that are essential for its biological function; 2. The protein should belong to HAT_MetX-like, HAT_MetX-like, HAT_MetX-like, HAT_MetX-like that shares evolutionary or... | MSDNTPTPQKNPDTNPYASLISQQIAIIPSFTLESGVTLNNVPVAYKTWGKLNEKADNCLVICHALTGSADVEDWWGPLLGLNKAFDPTRFFIFCGNVIGSPYGTISSVTTNPETGKPFGPEMPGSSVKDDVRLHYIILKSLGVRSVAAVVGGSMGGMTVLEYPLNTPPGFVRAIIPLATSARHSAWCISWGEAQRQSIYSDPDYKDGYYYEIEEEGGKVDLARQPARGLAAARMAALLTYRSRDSFESRFGRRAGGGKSSVPKGGVRIMGGQETTDPSVPSESDLAAKSPSWRAWREHNDGHRSAGARPISRSGSEGPA... | 528 | [
{
"id": "GO:0004414",
"name": "homoserine O-acetyltransferase activity "
}
] | [
{
"id": "IPR000073",
"name": "AB_hydrolase_1",
"type": "DOMAIN",
"begin": 60,
"end": 245
},
{
"id": "IPR008220",
"name": "HAT_MetX-like",
"type": "FAMILY",
"begin": 2,
"end": 496
},
{
"id": "IPR029058",
"name": "AB_hydrolase_fold",
"type": "HOMOLOGOUS_SUPE... |
ipr_go-000045 | 45 | sha256:f29b0e1a0dcfc0d2557bc357ee9d967f5b99c737bece29f23ad8fc02dedca365 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more NAT10/TcmA_helicase, GNAT_dom, TmcA_N, GNAT_dom, GNAT_dom that are essential for its biological function; 2. The protein should belong to tRNA_acetyltr_TmcA, TmcA/NAT10/Kre33 that s... | MTVKVRFDKEVRDYAKGEKVKDSILKLTETALAQALENFHRRMIVIEGDTLRKAELAGILAGASARVLSGILEELMKKRLRDESEDKIEVLYATDALGEETFGRKRYEAFRKHFDVLAGSNVEVKAVTFKHTRDILGRTYDLLILDMSYDYSPNDLGRIIETVRGGGLIFILAHPFEKWKNMWTGFHKSLVTPPYTIDDVKKRFNRRLIRKFTEHDGIYIITEGGKARKKPKRSKSQARIKARKGVPIPEETLFPKELYEMALTEGQVEVLKAFEELVEGGMLVLTADRGRGKSVSVGIGAIGLALALKKRTRIVVTAPE... | 811 | [
{
"id": "GO:1990883",
"name": "18S rRNA cytidine N-acetyltransferase activity "
},
{
"id": "GO:0005524",
"name": " ATP binding "
},
{
"id": "GO:0106162",
"name": " mRNA N-acetyltransferase activity "
},
{
"id": "GO:0019843",
"name": " rRNA binding "
},
{
"id": "GO... | [
{
"id": "IPR016181",
"name": "Acyl_CoA_acyltransferase",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 489,
"end": 643
},
{
"id": "IPR024914",
"name": "tRNA_acetyltr_TmcA",
"type": "FAMILY",
"begin": 36,
"end": 805
},
{
"id": "IPR027417",
"name": "P-loop_NTPase",... |
ipr_go-000046 | 46 | sha256:dd3fabbdff587c4be38842084fbf29b98933cc68a78e913808797784fa6be7ca | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PP-bd_ACP, Acyl_transferase_dom, PKS_Beta-ketoAc_synthase_dom, PKS_Beta-ketoAc_synthase_dom, Ketoacyl_synth_N, Ketoacyl_synth_N, Ketoacyl_synth_C, Ketoacyl_synth_C, PKS_a... | MTSGRGVSQMVTDDKLRYFLKKVTADLHETRGRLRELEEAAGEPIAVVAMGCRFPGGVRSPEDLWHLVASGRDAITPFPADRGWETAGLYDPDPDRPGKSCAREGGFLDDVASFDAGLFGVSPREALALDPQQRLLLEVTWETFERAGLTPAALRGTRTGVFVGTSSQEYAMLVHNARENFEGYSTGYLASVISGRLAYNFGLQGPAVTVDTACSSSLVALHQAAQALRAGDCTLALAGGVAVLATPSMFVEFSRQRGLAPDGRCKAFAAAADGTGWGEGVGLLLLERLSEARREGHPVLAVVRGSAVNQDGASNGLTAP... | 2,266 | [
{
"id": "GO:0004315",
"name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
},
{
"id": "GO:0004312",
"name": " fatty acid synthase activity "
},
{
"id": "GO:0031177",
"name": " phosphopantetheine binding "
}
] | [
{
"id": "IPR016039",
"name": "Thiolase-like",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 298,
"end": 336
},
{
"id": "IPR001227",
"name": "Ac_transferase_dom_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 1595,
"end": 1710
},
{
"id": "IPR009081",
"name": "PP-b... |
ipr_go-000047 | 47 | sha256:0958c03e3ca533a5b8bf96971c18d55c614d03d69fce1854a2849682754e8ded | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more NorB/c/GfsB-D-like_docking, SpnB-like_Rossmann, PKS_ER, ADH-like_N, Ketoacyl_synth_C, PKS_DH_N, PP-bd_ACP, Acyl_transferase_dom, PKS_Beta-ketoAc_synthase_dom, PKS_KR, PP-bd_ACP, PKS... | MPVGDDKLVEALRASLKETENLRARNRELRAAAREPVAVVAMGCRFPGGVKSPEDLWHLVAEGTDAISPFPADRGWDTDSLFDSDPGRPGHTYVLEGGFLDDAAEFDADLFGISPREAVAMDPQQRLLLETAWETFERAGINPASLRGRPVGTFVGSVLTTNGGGAEPAEGSEGHQLTGSAASVLSGRLAYTFGLEGPAVTVDTACSAALASVHLAVQALRQRECAMALAGGSAVLTTPGIFVEFSRQRGLAPDGRCKPFAAAADGTGWGEGVGLVLLERLSDARRRGHPVLAVIRGSAVNQDGASNGLTAPNGPSQQRV... | 2,174 | [
{
"id": "GO:0004315",
"name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
},
{
"id": "GO:0004312",
"name": " fatty acid synthase activity "
},
{
"id": "GO:0016491",
"name": " oxidoreductase activity "
},
{
"id": "GO:0031177",
"name": " phosphopantetheine binding... | [
{
"id": "IPR015083",
"name": "NorB/c/GfsB-D-like_docking",
"type": "DOMAIN",
"begin": 5,
"end": 31
},
{
"id": "IPR036291",
"name": "NAD(P)-bd_dom_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 1523,
"end": 1697
},
{
"id": "IPR016039",
"name": "Thiolase-like",... |
ipr_go-000048 | 48 | sha256:6db18e3049c4db7a15e53432569fa8988abdbbcfd20b33d5a1630806148114fe | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Acyl_transferase_dom, Acyl_transferase_dom, PKS_PP-bd, PKS_PP-bd, PKS_mFAS_DH, PKS_Beta-ketoAc_synthase_dom, Ketoacyl_synth_C, Ketoacyl_synth_C, PKS_DH, PKS_DH, SpnB-like_Rossmann, ... | MTKDDKTLDYLKRLTAELVQTRERLRTAQAASREPVAVVSMACRFPGGVSSPEELWRLVAAGRDGITPIPAGRGWDTEGLYDPDPDRVGKSYAREGGFLDDIASFDAGLFGISPREALVMDPQQRLLLEVSRETLERAGIAPGTLGGSRTGVFTGLMGGDYTARLPGILGEFEGQLEIGRAGSVASGRVAYTFGLEGPALTLDTACSSSLVALHLAVRALRDGECDLALAGGATLMSSPAALLEFSRQRALSPDGRCKAFAGQADGTGLAEGVGVVLLERLTDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGPAQQRV... | 3,625 | [
{
"id": "GO:0004315",
"name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
},
{
"id": "GO:0004312",
"name": " fatty acid synthase activity "
},
{
"id": "GO:0031177",
"name": " phosphopantetheine binding "
}
] | [
{
"id": "IPR014043",
"name": "Acyl_transferase_dom",
"type": "DOMAIN",
"begin": 2336,
"end": 2656
},
{
"id": "IPR014043",
"name": "Acyl_transferase_dom",
"type": "DOMAIN",
"begin": 564,
"end": 881
},
{
"id": "IPR006162",
"name": "Ppantetheine_attach_site",
... |
ipr_go-000049 | 49 | sha256:7a2b43eb4693bca9c8e214b8ce966e5161f55926389724de9065d4baf60d4ff1 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PKS_mFAS_DH, Ketoacyl_synth_C, PP-bd_ACP, Acyl_transferase_dom, PKS_DH_C, PKS_DH, PKS_Beta-ketoAc_synthase_dom, PKS_DH_N, PKS_Beta-ketoAc_synthase_dom, Acyl_transferase_dom, Ketoacy... | MELNGIRRRLATAKEAERHRLLLELIRAAAAEALDRPGPLPLDPGRAFGAQGVRGRAAGRLRERLSEATGLPLPATVVFDYPTPGALAGRLCALLLDEPAGPGGANGQMEAEEPIAIVGMGCRLPGDVRSPEGLWRLVHNGTDAISEFPEDRGWTVQQHPDPDHLGTTVTRHAGFLYDAPDFDAGFFAISPGEAVTIDPQHRLLLETTWKAVEDARIDPTSLRGSRTGVFVGLMYSEYGARIRRVPPGAEGYRVVGSMPSVASGRLAYTFGFEGPAVTVDTACSSSLVAMHLAAQSLRKGECTLAVAGGATVMATPWGYI... | 1,897 | [
{
"id": "GO:0004315",
"name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
},
{
"id": "GO:0004312",
"name": " fatty acid synthase activity "
},
{
"id": "GO:0031177",
"name": " phosphopantetheine binding "
}
] | [
{
"id": "IPR049900",
"name": "PKS_mFAS_DH",
"type": "DOMAIN",
"begin": 1012,
"end": 1289
},
{
"id": "IPR016039",
"name": "Thiolase-like",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 109,
"end": 535
},
{
"id": "IPR036291",
"name": "NAD(P)-bd_dom_sf",
"type":... |
ipr_go-000050 | 50 | sha256:4c5f6d841731f9123f3dbb4943a6017c6602477e2820756b25be4ef0e94f0333 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Epimerase_deHydtase that are essential for its biological function; 2. The protein should belong to UXS-like that shares evolutionary origin and functional similarity; 3. The protei... | MKKRCLITGGAGFIGSHLAEELVKRGHPVTIVDNFYKGKSKYHEELTGNIPIIPISILDKNSMHELVNQHDVVFHLAAILGVKTTMEKSIELIETNFDGTRNILQAALKGKKKVIFASTSEVYGKGTPPFSEDDDRLYGATSKIRWSYAICKTLEETLCLGYALQGLPVTIVRYFNIYGPRAKDGPYAGVIPRFIRAALQGDDLLVYGDGKQTRCFTYVSDAVEATIAAMDEKVNGEIINIGSEDEKSIQEVAQDIHQLTHSSSKIVHVPFEKVYPHGFEEIPNRKPDVTKLKEMCQFHPNVSWEQGLKETIQWFREIEN... | 321 | [
{
"id": "GO:0070403",
"name": "NAD+ binding "
},
{
"id": "GO:0048040",
"name": " UDP-glucuronate decarboxylase activity "
}
] | [
{
"id": "IPR036291",
"name": "NAD(P)-bd_dom_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 2,
"end": 318
},
{
"id": "IPR044516",
"name": "UXS-like",
"type": "FAMILY",
"begin": 2,
"end": 317
},
{
"id": "IPR001509",
"name": "Epimerase_deHydtase",
"type": "D... |
ipr_go-000051 | 51 | sha256:75ea9108a4ed3d75fa901ba65e99729712f4656bf9b3d0e96a0e505fcbdb5087 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to HODM_asu-like that shares evolutionary origin and functional similarity; 2. The protein must be able to perform the metal ion binding , oxidoreductase activity required for its activity.. Th... | MTLTFKPLESYREDFSFRNSPAAIARFPFPFPEDQYMYSVNLEPAVSRDPGSVFEHQFDVDEHYVSEMAERARVLELDPGRCLVMPHMAQAAWDTLAMLMEHLARDYPQHFRLTRQGDAWHWQNLALGIDQRFTFGDPASLPCEPLEYITRQMQGDFAVLDQRDGDLFMDAGMVTCPADWSLRFDAGMSFKQWHSPVPMAHQMGVFDRALKYLLNIQVGAPVRRLNWTLTINPRLDTSPETYHEWGNDRGKVTPDNVGRLVHLRVELQLMARLPRSNALLFGIRTYLISLDELVSNPAWAQRLHRVMRDLPDPIADYKGI... | 338 | [
{
"id": "GO:0046872",
"name": "metal ion binding "
},
{
"id": "GO:0016491",
"name": " oxidoreductase activity "
}
] | [
{
"id": "IPR021848",
"name": "HODM_asu-like",
"type": "FAMILY",
"begin": 54,
"end": 327
}
] |
ipr_go-000052 | 52 | sha256:5701a356f9ba6cc28118b5d389d3949cc97730b82b60c9cd29e8e61c0b097f59 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GCST_C, GCV_T_N that are essential for its biological function; 2. The protein should belong to GcvT/YgfZ/DmdA that shares evolutionary origin and functional similarity; 3. The prot... | MANSWRISALRERHLALGSQLEDWNGMGTAWTYASDLADHHEAIRTRAGLMDVSGLKKVHYVGPHAESLLDYATTRDIGKLYPGKSVYACLLDEDGKFIDDCIVYRTGPNAFMVVHGAGTGHEMLIRSAQGRQVAVLFDDDLHDLSLQGPRAVDFLAEHVPGIRDLPYFHHLQTKLFDRPVMISRTGYTGERGYEIFCKAADAPAIWDAILEQGKGYGIIPCAFTALDWLRVESYLLFFPYDNSQMYPFADQKAGDTLWELGLDFTVSPGKQDFRGAGEHYRLKGQERFKIFGVLLDGHQAAQGGDTLWHDGRQVGVITC... | 376 | [
{
"id": "GO:0008483",
"name": "transaminase activity "
}
] | [
{
"id": "IPR029043",
"name": "GcvT/YgfZ_C",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 290,
"end": 372
},
{
"id": "IPR028896",
"name": "GcvT/YgfZ/DmdA",
"type": "FAMILY",
"begin": 6,
"end": 370
},
{
"id": "IPR027266",
"name": "TrmE/GcvT_dom1",
"type": "HOM... |
ipr_go-000053 | 53 | sha256:cbb47158108f97238cc14ce956cc70f0fb0943b0f8d448be2b9c5b8a79125b44 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Tscrpt_reg_LuxR_C, Tscrpt_reg_LuxR_C, Tscrpt_reg_LuxR_C, Tscrpt_reg_LuxR_C, Tscrpt_reg_LuxR_C, Tscrpt_reg_LuxR_C, Tscrpt_reg_LuxR_C, Tscrpt_reg_LuxR_C that are essential for its bio... | MHGAAVTPPSTVSPTPVPTQSAPLSVALVSHRCPDPCEVTGFHSRRVHEPCEIRPSDDVVLFYGPRMGQELRRFSTEANGGLPPFAVLATCLDWDDVCLALDSGAIGYLLEIEDPDLLAAALHCISHGHTILAPQIAEHARVTSCPGGALRQTAAVARPDTSGSATGRTGDSSPSLALSPQEREIMTRLASGLSVREIAVEMRLAEKTVRNYLSHIYGKLGVRSRSQALLRWLGHPGGETAHH | 243 | [
{
"id": "GO:0003677",
"name": "DNA binding "
}
] | [
{
"id": "IPR000792",
"name": "Tscrpt_reg_LuxR_C",
"type": "DOMAIN",
"begin": 192,
"end": 208
},
{
"id": "IPR000792",
"name": "Tscrpt_reg_LuxR_C",
"type": "DOMAIN",
"begin": 208,
"end": 220
},
{
"id": "IPR000792",
"name": "Tscrpt_reg_LuxR_C",
"type": "DOMAI... |
ipr_go-000054 | 54 | sha256:8c808c334931f736971bfa2ca0a081c9bf0c4d0746f9c3710930efff95217302 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more ArsR-like_HTH, AsnC-type_HTH_dom, AsnC-type_HTH_dom, AsnC-type_HTH_dom, AsnC-type_HTH_dom, Tscrpt_reg_AsnC/Lrp_C that are essential for its biological function; 2. The protein shoul... | MSEGSSITGVQTPGSPKDVRARDLDDIDRRILLALHDDARIPNSALAEMVGIAPSTCHGRVRRLQEIGVIRGFYTDIDPAAVGLGLQAMISVSLQSNARGKIRSFIAHIRTRPQVMDVYFLAGGDDFILHVAARDTEDLRKFVVENLNADSDVAGTQTSLIFEHLRGASPL | 171 | [
{
"id": "GO:0043565",
"name": "sequence-specific DNA binding "
}
] | [
{
"id": "IPR011008",
"name": "Dimeric_a/b-barrel",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 84,
"end": 165
},
{
"id": "IPR011991",
"name": "ArsR-like_HTH",
"type": "DOMAIN",
"begin": 25,
"end": 71
},
{
"id": "IPR000485",
"name": "AsnC-type_HTH_dom",
"typ... |
ipr_go-000055 | 55 | sha256:bda6ab24214df28092cbdba9684d36de583471faedd3a23726c54f1bcc731122 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more 2Fe-2S_ferredoxin-type, 2Fe-2S_ferredoxin-type, DmmA-like_N, FAD-bd_FR_type, 2Fe-2S_ferredoxin-type that are essential for its biological function; 2. The protein should belong to M... | MSTLLDVRVAAIRELTPVIREYSFEALASTLPGFSAGSHVQLHLPNGRRNAYSLLSDPADTRQYRIAVRQQDASRGGSRYLHQHLKVGDRLRLSPPANLFPLHGEAQKHILVAAGIGITPFLAYSQELLRRGADFELHYAYRAGSSDAYVDELRQQLGPRLHEYLSGQRRLDLASLLQGRTLGTHVYACGPQSLLLDLQEQASAQGWSPRRVHWEAFAAAEPGQPFRVELARSGQQLEVAADESLLEALEAAGVEVPNLCRGGVCGQCQTPWLKGDVEHRDHFLSANERTSSLMPCVSRGCGSPILLDL | 309 | [
{
"id": "GO:0051537",
"name": "2 iron, 2 sulfur cluster binding "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
},
{
"id": "GO:0016491",
"name": " oxidoreductase activity "
}
] | [
{
"id": "IPR001041",
"name": "2Fe-2S_ferredoxin-type",
"type": "DOMAIN",
"begin": 227,
"end": 299
},
{
"id": "IPR001041",
"name": "2Fe-2S_ferredoxin-type",
"type": "DOMAIN",
"begin": 226,
"end": 309
},
{
"id": "IPR036010",
"name": "2Fe-2S_ferredoxin-like_sf",
... |
ipr_go-000056 | 56 | sha256:094f94f39d6a8f23eb2de3d8e4d1b9f242225c1d6c58b3aaf95af78970917f8f | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more EF3_4HB, TOG, AAA+_ATPase, AAA+_ATPase, ABC_transporter-like_ATP-bd, ABC_transporter-like_ATP-bd, eEF3_ABC2_chromodomain-like, ABC_transporter-like_ATP-bd, ABC_transporter-like_ATP-... | MSDSQQSVEVLNQLLARLSVATPDNRDEVATEVSSFVNGNIIEHDAPEHFFNGLAKAIKDKKSAVNALAAVSHVASTSGLAPSVEPYVVALVPAILEQTGSKDKDVQSAANAALHAVVTAVNPVAVKAVLPHLTKSLSETNKWQEKVAVLSAISALVDQAKSQISLRMTELIPVLSEAMWDTKKEVKNAATATMTKATETVENKDIERFIPKLIECIANPSEVPETVHLLGATTFVAEVTPATLSIMTPLLSRGLAERETPIKRKSAVIIDNMCKLVEDPQIVAPFLNKLLPGLKNNFSVIADPEAREVTLRGLKTLRRV... | 1,045 | [
{
"id": "GO:0005524",
"name": "ATP binding "
},
{
"id": "GO:0016887",
"name": " ATP hydrolysis activity "
},
{
"id": "GO:0003723",
"name": " RNA binding "
},
{
"id": "GO:0003746",
"name": " translation elongation factor activity "
}
] | [
{
"id": "IPR011989",
"name": "ARM-like",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 1,
"end": 328
},
{
"id": "IPR047038",
"name": "eEF3_chromodomain-like_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 762,
"end": 871
},
{
"id": "IPR050611",
"name": "ABCF_EF3_... |
ipr_go-000057 | 57 | sha256:3579d1a1040ea01e21c17e5edbd32710bf365c4f46ce4aef54d0eb0255558685 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to MID1/Yam8, MID1/Yam8 that shares evolutionary origin and functional similarity; 2. The protein must be able to perform the calcium channel activity required for its activity.. The designed p... | MPAREVYLKRPATRRQLEGICTRYDGQQRITQLDCEEGCSKRTQPPQRLNPRYKSPDLIHISFIIVLLCILSMTSSVVAQTTTGSSSSKAAATPILPRQTLPTTISLPPLNISHPVLQLALPPTSSLYLTFSICSLTSNATILPTVLISTSSPASFNLGSKPIRDASTGGIPTSSGGKGYNYKSGRNGATWGLKWSSGFGNWTLNGTSETQVHLLLGLGLGNDGSTLNTTGVGNGNVVVQMGASTSGPLHALSAVYPLLGDTTSTSALIFSPLLYSSPQPEPSYPNYTLPGAQLAFPDFSYSEPLNSSLSSNLTLIVVPT... | 623 | [
{
"id": "GO:0005262",
"name": "calcium channel activity "
}
] | [
{
"id": "IPR024338",
"name": "MID1/Yam8",
"type": "FAMILY",
"begin": 4,
"end": 622
},
{
"id": "IPR024338",
"name": "MID1/Yam8",
"type": "FAMILY",
"begin": 226,
"end": 598
}
] |
ipr_go-000058 | 58 | sha256:6d00535c3ebbeff04d3af934c13233820562fce90c7ddf3c72a7af047ff7f6fb | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to MavL-like that shares evolutionary origin and functional similarity; 2. The protein must be able to perform the ADP-ribosylarginine hydrolase activity required for its activity.. The designe... | MSTFGAEVDQVWPAVTGDSPHLTNFGRKLLKDCRQVQKPIGGYENLGNVIKLSAEFPLEFGVNSVKVYRQSPSRLARINEEVASAYPLIHERTLGLYLQYLEHKCRWGNAVEKPIYRNLSLCGFVQRLLVKRCASFFARNDKYLLVSGESGASGFEAVGTREEKAPLVLANVLSYDDIKLSALLSVSSRTEFVNEGERTNCGHVDLNTKTLERHGVIVGMIGARLSRRNLMEFQDIVIARQQNTRERGYGMALDEPATTRDEDYRRLWREFYATRDLIHGQAVIDNQRFGPSKNKMDVFDNLVMKRRYAISFDMLLLEAE... | 505 | [
{
"id": "GO:0003875",
"name": "ADP-ribosylarginine hydrolase activity "
}
] | [
{
"id": "IPR032063",
"name": "MavL-like",
"type": "FAMILY",
"begin": 48,
"end": 496
}
] |
ipr_go-000059 | 59 | sha256:e96e1998af231b58f41730af94d3c8781aa5e01347bc51d11e0d87abf78c384f | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to MavL-like that shares evolutionary origin and functional similarity; 2. The protein must be able to perform the ADP-ribosylarginine hydrolase activity required for its activity.. The designe... | MRSFLYMLSQRPKLACLCGKSIIIWPGKRTNLPENAFTQRMLQECGQMAKPDASVDLDNFKAISEQSPAEFGIDSCRVKAQPEDRSDRIREQIASAYPVIHERTLLLFISFLEHKLTFGSEQEKAIYKDMTVVDLVQRLLAKRCVWFFGANDYYRTMQGNIGNEGFEAVGTPAEKEPLTLTSVLSYDEIKLSALLYVSCHSEFINNGSRVNGGEVLQNKDTIEREGVVIGLIGARFERPDVMEYQDIMITKTQNTEANGYGFDLEQISSETVTPASDLRRIWREFYEEPRDFIYADTPYDTTRFEEVSQGIFDHQVMRKR... | 508 | [
{
"id": "GO:0003875",
"name": "ADP-ribosylarginine hydrolase activity "
}
] | [
{
"id": "IPR032063",
"name": "MavL-like",
"type": "FAMILY",
"begin": 59,
"end": 505
}
] |
ipr_go-000060 | 60 | sha256:49cc371409230fc3d0cbc8f8bdc420f356d9745fb1a72da717f3e884135a10b4 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GNAT_dom, GNAT_dom that are essential for its biological function; 2. The protein should be classified within Acyl_CoA_acyltransferase sharing conserved structural features; 3. The ... | MSGYSAPRRISDADDVTSFSSGEPSLDDYLRKRALANHVQGGSRCFVTCRDGRVVGFYALASGSVAHADAPGRVRRNMPDPVPVILLSRLAVDRKEQGRGLGSHLLRDAIGRCVQAADSIGLRAILVHALHDEARAFYVHFDFEISPTDPLHLMLLMKDARALIGD | 166 | [
{
"id": "GO:0016747",
"name": "acyltransferase activity, transferring groups other than amino-acyl groups "
},
{
"id": "GO:0000049",
"name": " tRNA binding "
}
] | [
{
"id": "IPR000182",
"name": "GNAT_dom",
"type": "DOMAIN",
"begin": 33,
"end": 143
},
{
"id": "IPR016181",
"name": "Acyl_CoA_acyltransferase",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 19,
"end": 150
},
{
"id": "IPR000182",
"name": "GNAT_dom",
"type": "DO... |
ipr_go-000061 | 61 | sha256:54d3ff73ff0c3b715a73ad8e414a47da4eccaddeb034918f99f730cb16a8aa1b | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Aca2_YdiL-like that shares evolutionary origin and functional similarity; 2. The protein should be classified within Lambda_DNA-bd_dom_sf, YdiL_sf sharing conserved structural features; 3. Th... | MTNKELQAIRKLLMLDVSEAAEHIGRVSARSWQYWESGRSAVPDDVEQEMLDLASVRIEMMSAIDKRLADGERPKLRFYNKLDEYLADNPDHNVIGWRLSQSVAALYYTEGHADLI | 116 | [
{
"id": "GO:0003677",
"name": "DNA binding "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
},
{
"id": "GO:0003723",
"name": " RNA binding "
}
] | [
{
"id": "IPR010982",
"name": "Lambda_DNA-bd_dom_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 1,
"end": 110
},
{
"id": "IPR015060",
"name": "Aca2_YdiL-like",
"type": "FAMILY",
"begin": 1,
"end": 112
},
{
"id": "IPR027910",
"name": "YdiL_sf",
"type": "HOM... |
ipr_go-000062 | 62 | sha256:a612e06364f2a61ecc32d4676e01385a6026b21430723412c7f02c64d1ef64ba | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more LCN-type_CS_alpha_beta_dom, Scorpion_toxin-like that are essential for its biological function; 2. The protein should belong to Scorpion_toxinL/defensin, Scorpion_toxinL, Scorpion_t... | LIGVKTEHGYLLDKYTGCKVWCVINNESCNGECKRRGGYYGYCYFWKLACFCQGARKSELWHYETNKCNGRM | 72 | [
{
"id": "GO:0019871",
"name": "sodium channel inhibitor activity "
},
{
"id": "GO:0090729",
"name": " toxin activity "
}
] | [
{
"id": "IPR002061",
"name": "Scorpion_toxinL/defensin",
"type": "FAMILY",
"begin": 9,
"end": 54
},
{
"id": "IPR044062",
"name": "LCN-type_CS_alpha_beta_dom",
"type": "DOMAIN",
"begin": 7,
"end": 69
},
{
"id": "IPR003614",
"name": "Scorpion_toxin-like",
"t... |
ipr_go-000063 | 63 | sha256:4c5f6ce116665066820aa85f61aa5d53cbd37564158534eb94cfe0b3bdb23c65 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GH43_C2 that are essential for its biological function; 2. The protein should belong to Glycosyl_Hydrlase_43, Glyco_hydro_43 that shares evolutionary origin and functional similarit... | MPQVRNPILPGFNPDPSILRVGEDYYIATSTFEWYPGVQIHHSRDLANWELVARPLNRKSQLDMRGNPDSCGIWAPCLSHDGERFWLVYTDVKRKDGSFKDTPNYIVTAEKIEGPWSDPIYINSSGFDPSLFHDDDGRKWFVNMLWDHRRRPQLFEGIVLQEFDPKAGKLVGPRKNIFTGTDLALVEGPHLYKRNGWYYLLTAEGGTGYEHACTFARSRNIWGPYEVHPQKYILTSKDHPHAALQRAGHGDIVDTPDGRTYLVHLTGRPTTQFRRCVLGRETAIQEAYWGDDDWLYVKNGPVPSLWVDLPAARDDTKYWE... | 538 | [
{
"id": "GO:0009044",
"name": "xylan 1,4-beta-xylosidase activity "
}
] | [
{
"id": "IPR051795",
"name": "Glycosyl_Hydrlase_43",
"type": "FAMILY",
"begin": 3,
"end": 529
},
{
"id": "IPR006710",
"name": "Glyco_hydro_43",
"type": "FAMILY",
"begin": 5,
"end": 294
},
{
"id": "IPR041542",
"name": "GH43_C2",
"type": "DOMAIN",
"begin... |
ipr_go-000064 | 64 | sha256:39f6a97cab7f2cacfcd71868b53ec0e747754ce4dcb5969ed28596b1d58ba3ca | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more ADH-like_N, PKS_ER that are essential for its biological function; 2. The protein should belong to Trans-enoyl_RdTase-like that shares evolutionary origin and functional similarity;... | MKAIISVSPGRAALVHDRPLPSLRNGYLLVRTKAVALNPTDWKHIEITERPGILFGCDYAGVVEKIGPGISSRFQVGDRVAGFVHGGNSQEPQDGAFAEYILAKADIQILIPEHMSFEEAATLGVGVTSVGQGLYQALQLPFPGTQGEDPKTPTEEQQPLLIYGGSTASGVLGIQFAKLSGFAPLAVCSPDHFDLVETLGAVAQFDYADGEEAVQEIQDYVDRMSKPLRLAWDTVSIPSSAQFCGDALSALDECHYASLLPIKCQRSDVTSTTTMAYTVFGEDWGMGATRFPAVATDAEFGRRWWALVQELLDQGRIQTH... | 353 | [
{
"id": "GO:0000166",
"name": "nucleotide binding "
},
{
"id": "GO:0016651",
"name": " oxidoreductase activity, acting on NAD(P)H "
}
] | [
{
"id": "IPR013154",
"name": "ADH-like_N",
"type": "DOMAIN",
"begin": 26,
"end": 112
},
{
"id": "IPR036291",
"name": "NAD(P)-bd_dom_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 115,
"end": 322
},
{
"id": "IPR020843",
"name": "PKS_ER",
"type": "DOMAIN",
... |
ipr_go-000065 | 65 | sha256:b38aba3fb12ec82d94d5fa0551bc63308cc63b7f88d8f4dd468f6e1bb172307d | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Urm1, Urm1, Urm1 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Beta-grasp_dom_sf, Mopterin_synth/thiamin_S_b sharing conserved structur... | MSSKAKLEEIPITVDFSGGLEMLFDNQRRHSISLPAKDTEGKPVTIAFLIDYICKKLMKDPRTDLFVLDNHIRPGILVLINDADWELEGEEAYEIQPNDNILFVSTLHGG | 110 | [
{
"id": "GO:0046872",
"name": "metal ion binding "
}
] | [
{
"id": "IPR015221",
"name": "Urm1",
"type": "FAMILY",
"begin": 12,
"end": 110
},
{
"id": "IPR012675",
"name": "Beta-grasp_dom_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 7,
"end": 110
},
{
"id": "IPR016155",
"name": "Mopterin_synth/thiamin_S_b",
"type... |
ipr_go-000066 | 66 | sha256:d42b4cf572896d3288a042ca015e5e514cb1ffc87385172c2a6bf7d9f7389ae0 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Elp3/MiaA/NifB-like_rSAM, rSAM, rSAM, rSAM, 4Fe4S-binding_SPASM_dom, 4Fe4S-binding_SPASM_dom that are essential for its biological function; 2. The protein should belong to Radical_... | MKTEDMALVFSKLILNPITKRQILNLFKKDDNGNLIIENYIDAYMKGEDINSLGYKTLKSVLDNGLKTFAGEIYKENFKDFLKDPLFKKGLISVVRGLGYFGVKRPFVSGAPFLVVWDVTYACNLRCKHCYANAGKPLEDELNTEEALKTIDILANSGVVAIAFSGGEPLMRKDLFELIDRAKDYNMQVSIASNGTMLNKTNAKKLKEHKVDFVQISLDGTKETHEKFRGIKGIYDKTIEGIKNVVDEDIFCAIATTATKLNYRDVPKVMDLAEELNVNYFMLYNYIPVGVGDYDIDLSPEEREELLNLLWEKLNNDTGK... | 466 | [
{
"id": "GO:0051539",
"name": "4 iron, 4 sulfur cluster binding "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
},
{
"id": "GO:0016491",
"name": " oxidoreductase activity "
}
] | [
{
"id": "IPR006638",
"name": "Elp3/MiaA/NifB-like_rSAM",
"type": "DOMAIN",
"begin": 113,
"end": 309
},
{
"id": "IPR007197",
"name": "rSAM",
"type": "DOMAIN",
"begin": 119,
"end": 272
},
{
"id": "IPR050377",
"name": "Radical_SAM_PqqE_MftC-like",
"type": "FA... |
ipr_go-000067 | 67 | sha256:04f8c5e9e85da67b086773ba9238fcda3b1271a5894d0e923953e09ca0f0172f | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more MFS_dom that are essential for its biological function; 2. The protein should belong to MFS_Vesicular_Transporter, MFS, MFS that shares evolutionary origin and functional similarity... | MGLFTDLVLYGIVLPALPFIMRNRFHIPNAELQHYTSGFLATYAGASVFFSVPAGWAASKLGSRQLFLGGLVFLFVATAIFAFSTSLALLVVSRLLQGMSTAVVWTAGLDMVQDTVDPSQIGVTIGTIFATISVGELAAPVLGGVLYERGGIAAVFAVSAVMLAIDLGLRGLVIDKKAAVKFESPCLIRSSAERSDHVASAPTVVEAQERTHEGTPLLPQDDDDDSDRYKIDRELGSIVQAIPLLYCFREPRLHLAMLLSFVQALFIGTFDATVPTEAESLFHFSSLQVGLVFIALMLPYFALGRLAGQAVDRFGTKAAA... | 456 | [
{
"id": "GO:0022857",
"name": "transmembrane transporter activity "
}
] | [
{
"id": "IPR036259",
"name": "MFS_trans_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 1,
"end": 196
},
{
"id": "IPR036259",
"name": "MFS_trans_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 245,
"end": 451
},
{
"id": "IPR020846",
"name": "MFS_dom",
"typ... |
ipr_go-000068 | 68 | sha256:351b6c74b4c2221103ffe06ad649dd3d536e0edd19c3a314131076b2cd6dfa5d | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more MFS_dom that are essential for its biological function; 2. The protein should belong to MFS that shares evolutionary origin and functional similarity; 3. The protein should be class... | MQTATALEDSANAPSPAASSQGQFDREIVPIDTADAGNSTKRSPLKVALIMVALCCAVFLHALDNTIITTALPTITAAFDLDAAYTWIGSTYLLAVAASTMVWAKISDVFGRKPIILSANLCFFTGSLIAALSANFAMLIAARAIQGIGGAGVNVLANICVGDLFSQRKRGLYYGVIGGVWAVALSLGPVVGGSLTESISWRWCFYINLPLCAVVFVIIILLLDVKTPKTPFGKGIAAIDWVGAALSIGSTLMILLALSLGGQTEPWNSATVICLVVFGFIGWILCFSWEASLAKYPLLPVSIFKQIPTLAVLAACFIQS... | 579 | [
{
"id": "GO:0022857",
"name": "transmembrane transporter activity "
}
] | [
{
"id": "IPR036259",
"name": "MFS_trans_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 237,
"end": 476
},
{
"id": "IPR020846",
"name": "MFS_dom",
"type": "DOMAIN",
"begin": 50,
"end": 540
},
{
"id": "IPR011701",
"name": "MFS",
"type": "FAMILY",
"begin... |
ipr_go-000069 | 69 | sha256:3e75444ef73a59ea32e1df8dd911f094a963233fecca96f1fb511d7b05e30d56 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Peptidase_M23, NMB0315-like_N that are essential for its biological function; 2. The protein should belong to Cell_wall_metabolism_enzyme that shares evolutionary origin and functio... | MAVFPLSAKHRKYALRALAVSIILVSAAYIALTERTERVRPQRVEQNLPPLSWGGSGVQTAYWVQEAVQPGDSLADVLARSGMARDEIARITEKYGGEADLRHLRADQSVHVLVGGDGGAREVQFFTDEDGERNLVALEKKGGIWRRSASEADMKVLPTLRSVVVKTSARGSLARAEVPVEIRESLSGIFAGRFSLDGLKEGDAVRLIYDSLYFHGQQVAAGDILAAEVVKGGTRHQAFYYRSDKEGGGGGNYYDEDGRVLQEKGGFNIEPLVYTRISSPFGYRMHPILHTWRLHTGIDYAAPQGTPVRASADGVITFKG... | 430 | [
{
"id": "GO:0046872",
"name": "metal ion binding "
},
{
"id": "GO:0004222",
"name": " metalloendopeptidase activity "
}
] | [
{
"id": "IPR011055",
"name": "Dup_hybrid_motif",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 140,
"end": 388
},
{
"id": "IPR016047",
"name": "Peptidase_M23",
"type": "DOMAIN",
"begin": 294,
"end": 387
},
{
"id": "IPR054512",
"name": "NMB0315-like_N",
"type"... |
ipr_go-000070 | 70 | sha256:446c919f832e44a2cb7c48c753dd503d70b078244fdd1258da6a8d172c0385a4 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more MeTfrase_dom, Methyltransf_11 that are essential for its biological function; 2. The protein should belong to Erg6_SMT_methyltransf that shares evolutionary origin and functional si... | MGPANSEGTMFDAFSREVGDYYDQANELLRAMFTDNVHYGYWPDPSSIDPLAEAGERMTEQLYERLDVSAGHKVLDVGCGVGKPAAWLARKTGATVKGANVSRNQLEVARDRVRSEGLEDRVSFDLADAMHLPYADDSFDRIWAIESMIHMPDRDQVMREMARVLRPGGRLAIADIVVRGTLDDVATAVVEGFCTLSTARSLEHIDNYPALVEKAGLDLLELTDVSEQTRPTGPAVLPAFDVLLPTLGEEGVAQSKKAWGDMFDLPQYGYVLLTAGKP | 278 | [
{
"id": "GO:0008757",
"name": "S-adenosylmethionine-dependent methyltransferase activity "
}
] | [
{
"id": "IPR020803",
"name": "MeTfrase_dom",
"type": "DOMAIN",
"begin": 29,
"end": 278
},
{
"id": "IPR029063",
"name": "SAM-dependent_MTases_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 15,
"end": 278
},
{
"id": "IPR029063",
"name": "SAM-dependent_MTases_sf... |
ipr_go-000071 | 71 | sha256:3d4dc52b597631e59a64783be5e860a730bbfab67f42372b245243370e45e6cb | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Sulfatase_N that are essential for its biological function; 2. The protein should be classified within Alkaline_phosphatase_core_sf, Alkaline_phosphatase_core_sf sharing conserved s... | MTDDQDVHLNSLDFQPISLLSFEGVAPYGPSCAQHKCHRCGPVLIDPGTCVYNNASMVLDNGAWAFHPGSYSTDLVANRSVEFLGDAIKAGEPFFLGVTPIAPHAETVGDAFEAPVPAKRHENLFLDVKVPRSPSFNAGAAGAVGYFRNLPKLAHDQIDYMDTFYRRRLQSLQAVDDLIEDIMAKLESHPDVLANTYLFYTSDNGYHIGQHRLPPGKTCGIEEDVNIPFIARGPGIAAGHVGRFPTSHTDLVPTIFELAGIPLRDEFDGEPMPLKGQRQSNDALNRNTYKTLRVDTDDYAFMYTVWCTNEHELYDMKMNN... | 424 | [
{
"id": "GO:0005539",
"name": "glycosaminoglycan binding "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
},
{
"id": "GO:0008449",
"name": " N-acetylglucosamine-6-sulfatase activity "
}
] | [
{
"id": "IPR000917",
"name": "Sulfatase_N",
"type": "DOMAIN",
"begin": 59,
"end": 261
},
{
"id": "IPR017850",
"name": "Alkaline_phosphatase_core_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 46,
"end": 322
},
{
"id": "IPR017850",
"name": "Alkaline_phosphatas... |
ipr_go-000072 | 72 | sha256:e316590a6f1ebb768b4cd2ae53d0b5fb1deefd8c6c5ffb22c77db65f75c3048a | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Pyrrolopyrazine_biosynth_F that shares evolutionary origin and functional similarity; 2. The protein should be classified within P-loop_NTPase, P-loop_NTPase sharing conserved structural feat... | MSANTGKPARHYLISYPRTASNLLLKILALDSQPNFSSGGFDGGYFFMPADDILTDPRIRVRARSISDWTADERAQLKETFQACFEAQQRWLESAESQGQSVFVKEHTVFFADPTARSCLQFGPSATSEPAWTVEYAGGSTHSKLNITVLPDEFLLTWLPTFLIRHPALAFPSLYRTVIKREGKESAAADNFASLLTTVEWSRSLYDFYVQNRESLPCSPDQRLEWPIVLDADDIIAHPATVTLYCDKIGMDPRQLCFNWDQLKSEELSKIEPNQLAMRMSLYQSTGIDTSKSSRGINVDDEATKWRSEFGIAVADHIEK... | 340 | [
{
"id": "GO:0016740",
"name": "transferase activity "
}
] | [
{
"id": "IPR027417",
"name": "P-loop_NTPase",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 7,
"end": 337
},
{
"id": "IPR027417",
"name": "P-loop_NTPase",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 11,
"end": 331
},
{
"id": "IPR053226",
"name": "Pyrrolopyrazine_b... |
ipr_go-000073 | 73 | sha256:b256b68cfd3ed8b59941ec1d71aba386118a2dce105bd6733b69c36c45f6f404 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Endo_G_ENPP1-like_dom, Endo_G_ENPP1-like_dom that are essential for its biological function; 2. The protein should belong to Non-specific_endonuclease that shares evolutionary origi... | MALKLVYGVFTLALLGISSVNADCSLKIPESVENEKTPVIMVRKSLKTFEYDLFQPTGEVTNFPERTELLLACTGAQNYFKNGEESVTLMCHNNEFDDGQGNGLDLFTCVKTPTAELRKTKERCSLGDLYVYDVVFRISEEELVGPVYDICYNEYSQKPAYSRNIINGAAVNYRVPESETDLTVSLAKDFTTRDVNNYFKLENQKQRFQGYTIDGKPLVDDKNFFAPGQLAPDTSMITPADKLSTYDYANIVPQYKTVYDGNVWRVENITRDLAVNRQAKFEVYTGGYERLTALHNGKEEEIFLSAKKYVHEIPKYIYKF... | 399 | [
{
"id": "GO:0004536",
"name": "DNA nuclease activity "
},
{
"id": "GO:0003690",
"name": " double-stranded DNA binding "
},
{
"id": "GO:0003725",
"name": " double-stranded RNA binding "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
},
{
"id": "GO:0004521",... | [
{
"id": "IPR044925",
"name": "His-Me_finger_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 129,
"end": 380
},
{
"id": "IPR044929",
"name": "DNA/RNA_non-sp_Endonuclease_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 136,
"end": 386
},
{
"id": "IPR001604",
"na... |
ipr_go-000074 | 74 | sha256:c6b04aca6b77a300ece42f879e4e7416e0160e8a2e8105428c5cd707da8513d3 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more ALL3/gSG7_salivary-like_helix that are essential for its biological function; 2. The protein must be able to perform the collagen binding , toxin activity required for its activity... | MKKFCLIFLLLALTALHVKGSPIPDEESEETEDAEQEEDAEEEEHAEEEAQEDGDQTQDTDQESDDGQEETANQGSDEQQEEDGSHGTDETDDEAAGSRTEDVESGGDEQNDGEENGSQENGEEVTGGEDDSHGAQDSEGGEEDAAAQEAGGKKSKGKGAKGGQGSNRAGSSSGGEESAAHTYQEVMRILNGIKINAKEPLKSRLVNGLQYLKVDTINRVENIQKFSRIEHCFGNLDHIVQLYAGDAVERNDYCKGTCIDMVSNEFRGQMEELTSRLYPCLQGGYY | 286 | [
{
"id": "GO:0005518",
"name": "collagen binding "
},
{
"id": "GO:0090729",
"name": " toxin activity "
}
] | [
{
"id": "IPR056799",
"name": "ALL3/gSG7_salivary-like_helix",
"type": "DOMAIN",
"begin": 176,
"end": 281
}
] |
ipr_go-000075 | 75 | sha256:578ee40d19a4187b96bbd813dd5b2ad6c5cd4952c2e58954fc66e0445da2dd06 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to BKACE, BKACE that shares evolutionary origin and functional similarity; 2. The protein should be classified within Aldolase_TIM sharing conserved structural features; 3. The protein must be a... | MTQPCIISVAITGSLPRKRDNPAVPITVSEQVESTQAAFEAGATLVHLHVRNDDETPSSEPDRFARVLEGIRKHAPGIITQVSTGGRSGAGRERGGMLSLRPDMASLATGSVNFPTRVYDNPPDLVDWLAAEMKAYAIKPEIEAFDLSMIFQAVAMQQAGKIDGALHIQFVMGIKNAMPVDREVLAFYVHTLRRLAPDATWTGAGIGRDQLTMARWSLELGGHCRTGLEDNVRLDKQTLAPSNAALVSQVAALCEEYGRPVATVAQARALLGLPSMEIDGRSPW | 284 | [
{
"id": "GO:0043720",
"name": "3-keto-5-aminohexanoate cleavage activity "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
}
] | [
{
"id": "IPR008567",
"name": "BKACE",
"type": "FAMILY",
"begin": 1,
"end": 274
},
{
"id": "IPR013785",
"name": "Aldolase_TIM",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 1,
"end": 277
},
{
"id": "IPR008567",
"name": "BKACE",
"type": "FAMILY",
"begin": ... |
ipr_go-000076 | 76 | sha256:86e7775d2c3efdc712e64c582cb59db1c9580212486a9fc40859683375ed2ad6 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom that are essential for its... | MAAFADRPTCRVSLGAVFLARELHRLRKSLPLCVFSLFLFSFAFSALSGAPSQFAEAAMPKLSGEKLAELMQMDVKDIKERMLALFDLIDTNQDNTIDTEEAKEWSAKLKNAMHQHQVRMEFQAIDKDNDGKVSLSELEATYVDSLDQKQLEQHKKEVEQRFKTVDKDNDGLLDLSEIRILMDPGKDEGLMKIEIEEILNAQDKNGDRKITVTEFIETEGTGSLNDVEKTELEKEFKSYDLNADGAIDVEELQQIIKDPHSHEIRMLLEEFTKDLKDGKVGREQWEKEFESFAVSMLTDNGEVLRFPEDYSGIEFPFKTA... | 335 | [
{
"id": "GO:0005509",
"name": "calcium ion binding "
}
] | [
{
"id": "IPR018247",
"name": "EF_Hand_1_Ca_BS",
"type": "BINDING_SITE",
"begin": 166,
"end": 178
},
{
"id": "IPR002048",
"name": "EF_hand_dom",
"type": "DOMAIN",
"begin": 156,
"end": 217
},
{
"id": "IPR002048",
"name": "EF_hand_dom",
"type": "DOMAIN",
... |
ipr_go-000077 | 77 | sha256:5637bb48855b6d87cd36ad891868d92d2dc8b55e927316cb25bd8ca9a617a679 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Prot_kinase_dom that are essential for its biological function; 2. The protein should belong to MAP_kinase, MAPK_Sty1/Hog1, MAPK_p38-like, MAPK_p38-like, MAPK_p38-like, MAPK_p38-lik... | MAEFVRAQIFGTTFEITSRYTELAPVGMGAFGLVCSAKDQLTNQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENVISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSVGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVQSLPKRERQPLTKKFKNADPQAIELLERMLVFDPRTRIRAGDALADPYLAPYHDPTDEPEAEEKFDWSFN... | 355 | [
{
"id": "GO:0005524",
"name": "ATP binding "
},
{
"id": "GO:0004707",
"name": " MAP kinase activity "
}
] | [
{
"id": "IPR050117",
"name": "MAP_kinase",
"type": "FAMILY",
"begin": 18,
"end": 307
},
{
"id": "IPR011009",
"name": "Kinase-like_dom_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 5,
"end": 338
},
{
"id": "IPR008271",
"name": "Ser/Thr_kinase_AS",
"type":... |
ipr_go-000078 | 78 | sha256:7c36d5c7fae62fcbb8bf70a0ab3d89954fbfbbc6fd19a54c7c3dda630ce5c242 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Eqnu_transpt, Eqnu_transpt, ENT1/ENT2, Eqnu_transpt, Eqnu_transpt, Eqnu_transpt that shares evolutionary origin and functional similarity; 2. The protein should be classified within MFS_trans... | MSSHTSTPNHASAAPPRKWYDMTSAEFYVYVVAFMCGISMLMPINAVFSAPSYMLQYYLYATKDPNHVPQMTNFWSNVMTYYNLIGLVTGLVMEPLTLLKSFRKIPMLVRLLGGLCILIVEIIVLMAVPARGTTEGGAVATMCIAGFIGGLGKSIFESTVYGMFGAFPPSFTSIMMGGVGISGVLTSLIQIIVKAALPDTYEGVKKQSYIYYSLDVGIQAATFIALIMMRFNSFAQLHFGDLGGVKSKVDAGSLAGAGENVREPGAEATELEQYTEPAIGQIQEKNAEAHKDDPLVDREHSDDVDEHGDALRAVEGPTSN... | 496 | [
{
"id": "GO:0005337",
"name": "nucleoside transmembrane transporter activity "
}
] | [
{
"id": "IPR002259",
"name": "Eqnu_transpt",
"type": "FAMILY",
"begin": 151,
"end": 488
},
{
"id": "IPR002259",
"name": "Eqnu_transpt",
"type": "FAMILY",
"begin": 25,
"end": 491
},
{
"id": "IPR034764",
"name": "ENT1/ENT2",
"type": "FAMILY",
"begin": 33... |
ipr_go-000079 | 79 | sha256:c29de6f54eb7b3652e0ebb99edcca36018a5532e49d71f579a4be901d48f70b5 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more TrpB-like_PALP, Thr_synth_N that are essential for its biological function; 2. The protein should belong to Threonine_Synthase, Thr_synthase-like that shares evolutionary origin and... | MAQEMRYFSTRGGKETLSFEDAVLTGLAPNGGLYIPTHIPALPKDWKTKWAGLSFPELSHEILSLFVPTSVIPSDDLQSIINTAYSSFRSPATTPIRQTGDNEYVLELWHGPTWAFKDVALQFLGELFRYFLERRNKDKTEDMEELTVVGATSGDTGSAAIYGLRSKPSITIFILYPDGRVSPIQEAQMATVPDANVYCVAVEDSDFDTCQSIVKTLFSDAQFNATHRLGAINSINWARILAQIVYYFSAYFQLPEEARKDGAKLQFVVPTGNFGDILAGWYAKKLGLPMEQLVVATNENDILERFFRTGRYEADDAVQQ... | 547 | [
{
"id": "GO:0030170",
"name": "pyridoxal phosphate binding "
},
{
"id": "GO:0004795",
"name": " threonine synthase activity "
}
] | [
{
"id": "IPR036052",
"name": "TrpB-like_PALP_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 113,
"end": 514
},
{
"id": "IPR001926",
"name": "TrpB-like_PALP",
"type": "DOMAIN",
"begin": 97,
"end": 349
},
{
"id": "IPR037158",
"name": "Thr_synth_N_sf",
"type... |
ipr_go-000080 | 80 | sha256:0d5b6ca56754f8b7a34530cb0993479508f4e035318ede70547b7393e120e776 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GHMP_kinase_N_dom, GHMP_kinase_C_dom that are essential for its biological function; 2. The protein should belong to Homoserine_kinase, Homoserine_kinase, Homoserine_kinase that sha... | MPARKYKIHVPCTSANIGPGFDVCGIALSLSLSLVVTIPSVSSGAEPLPKIIYTGLDSDNVPLSPYKNLLTRVALYVLRANGITTFPPGVTIEARNEIPFGRGLGSSGAAVIAGVLLGDLLGNLSLPKSRLLDFALMVERHPDNVTAALMGGFVGSYLRELSPEDMSAASIPLAEVLPEYPPDAGPDWGKSPPQPPHGIGHFVRFGWAKEIKAIAVSPRFELATAKARGVLPESYSRKDMIFNLQRLAVLTTALARSPPDPDLIYDAMGDRVHQPYRMTLIPGLPKILSTLTPTSHPGLLGICLSGAGPTILALATHNFE... | 357 | [
{
"id": "GO:0005524",
"name": "ATP binding "
},
{
"id": "GO:0004413",
"name": " homoserine kinase activity "
}
] | [
{
"id": "IPR014721",
"name": "Ribsml_uS5_D2-typ_fold_subgr",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 5,
"end": 173
},
{
"id": "IPR006203",
"name": "GHMP_knse_ATP-bd_CS",
"type": "CONSERVED_SITE",
"begin": 98,
"end": 109
},
{
"id": "IPR036554",
"name": "GHMP... |
ipr_go-000081 | 81 | sha256:f43c07841a6175c125bba9ab5474c67719d466b07295c69b50449f964246f483 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cytochrome_P450_monoxygenase, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf,... | MNDFVFSDIPDILKPMASVEFDDPLTKATGDVLNWTLWLIRNFPALSNIIMRLPSSLVSIVTSSFEGANQMFQVTTSTHNLYSASLPTHATKQIISKLVEHEKTHIGPKNKDCVVQRLLNAHRDSESKISIPTPDATVRSEAIGFTLAGTADPPNILALGTFMAARDPEMQEGLYKELRAVWPDLRSPVPSYNLLHQLPLLRGVVKESIRFTHGVATGPARLVGAGGARIGGYNVPAKASLAVVAAPSYFVHMDETVFSEPEKFEPRRWADNDYSKSLVAFSRGRRMCPAEQFHVEPYETTSVPRSEERG | 310 | [
{
"id": "GO:0020037",
"name": "heme binding "
},
{
"id": "GO:0005506",
"name": " iron ion binding "
},
{
"id": "GO:0004497",
"name": " monooxygenase activity "
},
{
"id": "GO:0016705",
"name": " oxidoreductase activity, acting on paired donors, with incorporation or reduc... | [
{
"id": "IPR050121",
"name": "Cytochrome_P450_monoxygenase",
"type": "FAMILY",
"begin": 117,
"end": 293
},
{
"id": "IPR036396",
"name": "Cyt_P450_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 88,
"end": 293
},
{
"id": "IPR036396",
"name": "Cyt_P450_sf",
... |
ipr_go-000082 | 82 | sha256:15799a948141cc834792097224072e0866bb99a08601d2dffad614221d57bc06 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more DIOX_N, Oxoglu/Fe-dep_dioxygenase_dom, IPNS-like_FE2OG_OXY that are essential for its biological function; 2. The protein should belong to Iron_ascorbate_oxido_reductase that shares... | MATDTAVTGAPETMQLRLASGNGPVTRTVLRTPLRDALPSEVPLIDISPIFSTSVADRKAVACKIHDAATNIGFFYIQNHRVPSRDTDMAYSASLDFFRQDMEAKMKADAKKGPFDSGYRGPGTQRVNPDEGADLRETYSILYDPMLDPTVPDPARIPEPASRFLHLGRAPFESTDTLPHFKDAFVRYFQACLALARALTRTFALSLDLPESAFDSKVQYPDASLEINFYPPISTGHAVSAPADPDTRVSIGSHTDFLLFTILWQDSNGGLQVLNREGQWIRASPVEGTFVVNIGDYLQRITNDKYVSTVHRAQNWSGRQ... | 374 | [
{
"id": "GO:0051213",
"name": "dioxygenase activity "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
}
] | [
{
"id": "IPR027443",
"name": "IPNS-like_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 36,
"end": 370
},
{
"id": "IPR026992",
"name": "DIOX_N",
"type": "DOMAIN",
"begin": 42,
"end": 149
},
{
"id": "IPR005123",
"name": "Oxoglu/Fe-dep_dioxygenase_dom",
"typ... |
ipr_go-000083 | 83 | sha256:1fcf124c6af1a1ae3c9cc65efd0c7e27b3e95d4c128b261f2675580e165f0de2 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cytochrome_P450_monoxygenase, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV that shares evolutionary origin and functional similarity; 2. The protein should be classified ... | MLSIDHVDWLELIRVTLHPLAKFPGPKLAGASYCYEFWYEVICGIQYTQKIIKLHEQYGPIVRINPDELHFNDVDFVDVVYTAGARKRDKSSHYLAGFGGVSKSTFGTLDHMHHRTRRRALNKFFSKSRVLQIEDSIHEKSQQLCDKFLAYRDQGPFDLTGAFSCIATDTVTEYCFGSSPGFLNQDGWEPNCKSYFETIERMAHVTRHVPWILYLAKWLPLSIIRLVSSDLNSFLVDTRVKKPERLKRVVLDAERHDAKDCPVFLELLNSDLPPREKSKQRFMYEANGATLAGSGSTAIAMSNIVYNLVANPRIGHKLRS... | 476 | [
{
"id": "GO:0020037",
"name": "heme binding "
},
{
"id": "GO:0005506",
"name": " iron ion binding "
},
{
"id": "GO:0004497",
"name": " monooxygenase activity "
},
{
"id": "GO:0016705",
"name": " oxidoreductase activity, acting on paired donors, with incorporation or reduc... | [
{
"id": "IPR001128",
"name": "Cyt_P450",
"type": "FAMILY",
"begin": 47,
"end": 456
},
{
"id": "IPR036396",
"name": "Cyt_P450_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 14,
"end": 460
},
{
"id": "IPR050121",
"name": "Cytochrome_P450_monoxygenase",
"typ... |
ipr_go-000084 | 84 | sha256:f48b94d6f355bf8e5650f2c39faa975bca6e218bfc3f31517d3877bb6c667b4d | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within PBP_GOBP_sf, PBP_GOBP_sf sharing conserved structural features; 2. The protein must be able to perform the odorant binding , toxin activity required for its activity.. The designe... | MSFLFFLVVLISIGLWVGPCVADNPENRCIKQFAKTNPACIVHCKYNLYKFTDDNYDITDQHINKFTDVLIKNKAVDGSKKSQVQEHLKKCAEESLKKTHGKNCQRLVEYYSCAVDNKLIDYFKYESAINSYDRSIYTPPYSG | 143 | [
{
"id": "GO:0005549",
"name": "odorant binding "
},
{
"id": "GO:0090729",
"name": " toxin activity "
}
] | [
{
"id": "IPR036728",
"name": "PBP_GOBP_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 23,
"end": 138
},
{
"id": "IPR036728",
"name": "PBP_GOBP_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 30,
"end": 123
}
] |
ipr_go-000085 | 85 | sha256:bc6c2009a018016632e04e6729699a50d79a11a42eb2d56772d205cff0944374 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more TF_Kbox, TF_Kbox, TF_MADSbox, MEF2-like_N, TF_MADSbox, TF_MADSbox, TF_MADSbox, TF_MADSbox, TF_MADSbox, TF_MADSbox that are essential for its biological function; 2. The protein shou... | MGRGRVELKRIENKINRQVTFSKRRNGLLKKAYELSVLCEAEVALIIFSSRGKLYEFGSAGITKTLERYQRCCLNPQDNCGERETQSWYQEVSKLKAKFEALQRTQRHLLGEDLGALSVKELQNLEKQLEGALAQARQRKTQIMMEQMEELRRKERHLGDVNKQLKIKVSLELSSFEGEGQGVPFPWSNCNASLDEAGSSTFHVHHSQSNHMDCDLPDPVLQIGYHQYMAADGASGSRNMAVESNIIHGWGL | 252 | [
{
"id": "GO:0000981",
"name": "DNA-binding transcription factor activity, RNA polymerase II-specific "
},
{
"id": "GO:0046983",
"name": " protein dimerization activity "
},
{
"id": "GO:0000978",
"name": " RNA polymerase II cis-regulatory region sequence-specific DNA binding "
}
] | [
{
"id": "IPR002487",
"name": "TF_Kbox",
"type": "DOMAIN",
"begin": 82,
"end": 169
},
{
"id": "IPR002487",
"name": "TF_Kbox",
"type": "DOMAIN",
"begin": 85,
"end": 175
},
{
"id": "IPR002100",
"name": "TF_MADSbox",
"type": "DOMAIN",
"begin": 10,
"end... |
ipr_go-000086 | 86 | sha256:2e8788df8496584049759195f5fde6a8aa4eb5ba3967d17a73b09b64771bfd14 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GPCR_Rhodpsn_7TM that are essential for its biological function; 2. The protein should belong to OR51/52/56-like, GPCR_Rhodpsn, GPCR_Rhodpsn, Olfact_rcpt, Olfact_rcpt, Olfact_rcpt, ... | MGSNITSTSIIFLLTGVPGLEAFHTWISIPFCFLSVTALLGNSLILFATITQPSLHEPMYYFLSMLSATDLGLSISTLVTMLSIFWFNVREISFNACLSHMFFIKFFTVMESSVLLAMAFDRFVAVSNPLRYAMILTDSRIAQIGVASVIRGLLMLTPMVALLIRLSYCHSQVLHHSYCYHPDVMKLSCTDTRINSAVGLTAMFSTVGVDLLLILLSYVLIIRTVLSVASPEERKETFSTCVSHIVAFAIYYIPLISLSIVHRFGKQAPAYVHTMIANTYLLISPLMNPVIYSVKTKQIRRAVIKILHSKET | 312 | [
{
"id": "GO:0004930",
"name": "G protein-coupled receptor activity "
},
{
"id": "GO:0004984",
"name": " olfactory receptor activity "
}
] | [
{
"id": "IPR050402",
"name": "OR51/52/56-like",
"type": "FAMILY",
"begin": 8,
"end": 308
},
{
"id": "IPR000276",
"name": "GPCR_Rhodpsn",
"type": "FAMILY",
"begin": 110,
"end": 126
},
{
"id": "IPR000276",
"name": "GPCR_Rhodpsn",
"type": "FAMILY",
"begin... |
ipr_go-000087 | 87 | sha256:a3cd8b79d32ae17eba4fa3ed8ce06c955edb47dc505289a62470b87e3164773e | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Znf_CCHC, Znf_CCHC, Znf_CCHC that are essential for its biological function; 2. The protein should be classified within Znf_CCHC_sf sharing conserved structural features; 3. The pro... | MAGKNMSSRLLNMKFMQRASASTPTTPTTPDGTRPSKRLRTEAAPSPETRAFQEAAAAEEAKKNAFIERAAAEAGETKWVLSVSDDKPKTAGQGLRIVEAGYGAIDSGAPIPESDDDQDEEQSAGMAGRRSFGKFNKAVERQHNPDLSSPESEQDSDASSDSDSDDDEDLDEAELLIKAERKEAAAKLRAERKAQRKADEVKSKQMAERRRSRDINLNKVGGISNAAIRNKQANVANMACHVCGQKGHLQKDCPDRKQRRGDKRKSGGAMDY | 272 | [
{
"id": "GO:0003676",
"name": "nucleic acid binding "
},
{
"id": "GO:0008270",
"name": " zinc ion binding "
}
] | [
{
"id": "IPR001878",
"name": "Znf_CCHC",
"type": "DOMAIN",
"begin": 239,
"end": 255
},
{
"id": "IPR001878",
"name": "Znf_CCHC",
"type": "DOMAIN",
"begin": 239,
"end": 254
},
{
"id": "IPR001878",
"name": "Znf_CCHC",
"type": "DOMAIN",
"begin": 240,
"... |
ipr_go-000088 | 88 | sha256:6f138603563b5b34481d3d083d9e6174741b3d962eda8324cf8e0e4d8c656576 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more FSH-like_dom that are essential for its biological function; 2. The protein should belong to LovG that shares evolutionary origin and functional similarity; 3. The protein should be... | MKFLCLHGAYGNIPAFRVQLGPMIDALEFDGSASFEFIQGRVSVVPPPGFESYFGPAPHYRFLKDRGEAEASAVEGIRVFPEAETPEDALRALMPRDDMEIGFADARGLALEQLYEALDADPEISGIIGYSEGASAAATLVYDEQERMRSEGYVPRIKAAIFFMGWPALTAENVPALSDEVENLLEVPSLHIVGANDPYKDGALALYNIFDDNMAVFFDSAGGHTIPRHGKLLQELVSAVKDLIADVPEDNSADLLAPAVTGKRLDSAVDIPNLSFLKNEDA | 282 | [
{
"id": "GO:0016787",
"name": "hydrolase activity "
}
] | [
{
"id": "IPR029058",
"name": "AB_hydrolase_fold",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 1,
"end": 247
},
{
"id": "IPR005645",
"name": "FSH-like_dom",
"type": "DOMAIN",
"begin": 2,
"end": 232
},
{
"id": "IPR029058",
"name": "AB_hydrolase_fold",
"type":... |
ipr_go-000089 | 89 | sha256:b6243c25f76bd5341c3276e5e72351d95b636da19da05dae2fa407490c6e3c1c | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more ADH-like_C, ADH-like_N that are essential for its biological function; 2. The protein should belong to SDH-like that shares evolutionary origin and functional similarity; 3. The pro... | MVKPTKSNIGVYTNPAHDLWVAEAEPSLEQVQTGEKLAPGEVTVAVKSTGICGSDVHFWHAGCIGPMIVEDDHILGHESAGVVVAVHENVKSLKVGDRVAIEPNIICGECEPCLTGRYNGCDSVLFRSTPPVPGLLRRYVNHPAMWCHKIGDMSYENGSLLEPLSVALAGVQRAEVRLGDPILVCGAGPIGLVTLACVKAAGAEPIIITDIDEGRLAFAKEFCPSVRTHKVDFKHTPEDFAKAITELGGGVEPAIALECTGVESSIAGAIQTVKFGGKVFVIGVGKNEIKIPFMRLSTREVDLQFQYRYANTWPRAIRLL... | 368 | [
{
"id": "GO:0003939",
"name": "L-iditol 2-dehydrogenase (NAD+) activity "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
},
{
"id": "GO:0000166",
"name": " nucleotide binding "
}
] | [
{
"id": "IPR036291",
"name": "NAD(P)-bd_dom_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 157,
"end": 322
},
{
"id": "IPR013149",
"name": "ADH-like_C",
"type": "DOMAIN",
"begin": 189,
"end": 321
},
{
"id": "IPR013154",
"name": "ADH-like_N",
"type": "DOMA... |
ipr_go-000090 | 90 | sha256:f9efb2ff7aa180eeabc786a7977e270a8c9cd2fd962488aafcf245e2b9ee2848 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to TacA_1-like, TacA, TacA_1-like that shares evolutionary origin and functional similarity; 2. The protein should be classified within Ribbon_hlx_hlx sharing conserved structural features; 3. T... | MHRAGAAVTANVWCRAGGIRMAPRPVIPVATQQRLRRQADRQSLGSSGLPALNCTPIRHTIDVMATKPERKTERLAARLTPEQDALIRRAAEAEGTDLTNFTVTAALAHARDVLADRRLFVLTDAAWTEFLAALDRPVSHKPRLEKLFAARSIFDTEG | 158 | [
{
"id": "GO:0003677",
"name": "DNA binding "
}
] | [
{
"id": "IPR014795",
"name": "TacA_1-like",
"type": "FAMILY",
"begin": 63,
"end": 156
},
{
"id": "IPR010985",
"name": "Ribbon_hlx_hlx",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 71,
"end": 148
},
{
"id": "IPR016547",
"name": "TacA",
"type": "FAMILY",
... |
ipr_go-000091 | 91 | sha256:c00401d878260e5a5c15ceaae3e9851159bc2fc996a8543018238eee1e7f810e | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more DIOX_N, IPNS-like_FE2OG_OXY, Oxoglu/Fe-dep_dioxygenase_dom that are essential for its biological function; 2. The protein should belong to Iron_ascorbate_oxido_reductase that shares... | MRSVSPQSTMARIPERRVRTLDFAQFRHGEPSGSRGFCRELVDCLSSVGFVKIRNHGISGQEIENVFVMSQLFFSLPQAAKGKAAHPPEANPHRGYSYVGQEKLSRVKDYEKGKREITDVYDIKHYPIDRDARQESYDQGAAVDNLYPNRWPDEQDIPGFRVLMETFYERCHEVHQDILRAIAIGFDLSPSFLTDLCCQNTSELRLNHYPSVHPSSLRKGAKRISEHTDFGTVTLLFQDSVGGLEIEDQNTPGTYFPVLSERKSDIIVNIGDCIQRWTNDKIHSTSHRVVLPEDTDALTKDRYSVAYFGKPSRSQLVGSL... | 349 | [
{
"id": "GO:0051213",
"name": "dioxygenase activity "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
}
] | [
{
"id": "IPR026992",
"name": "DIOX_N",
"type": "DOMAIN",
"begin": 20,
"end": 154
},
{
"id": "IPR044861",
"name": "IPNS-like_FE2OG_OXY",
"type": "DOMAIN",
"begin": 204,
"end": 309
},
{
"id": "IPR050231",
"name": "Iron_ascorbate_oxido_reductase",
"type": "FA... |
ipr_go-000092 | 92 | sha256:88c8b13c2b6628205cc8c95fa4d4f556dbb08496ed1543ab787445094458fe1b | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Tscrpt_reg_HTH_GntR, Tscrpt_reg_HTH_GntR, Tscrpt_reg_HTH_GntR that are essential for its biological function; 2. The protein should be classified within WH-like_DNA-bd_sf, WH_DNA-bd... | MELRDWLRVDVKAGKPLFDQLRTQVIDGVRAGALPPGTRLPTVRDLAGQLGVAANTVARAYRELESAAIVETRGRFGTFISRFDPTDAAMAAAAKEYVGVARALGLTKSDAMRYLTHVPDD | 121 | [
{
"id": "GO:0003677",
"name": "DNA binding "
},
{
"id": "GO:0003700",
"name": " DNA-binding transcription factor activity "
}
] | [
{
"id": "IPR000524",
"name": "Tscrpt_reg_HTH_GntR",
"type": "DOMAIN",
"begin": 21,
"end": 80
},
{
"id": "IPR000524",
"name": "Tscrpt_reg_HTH_GntR",
"type": "DOMAIN",
"begin": 15,
"end": 83
},
{
"id": "IPR036388",
"name": "WH-like_DNA-bd_sf",
"type": "HOMOL... |
ipr_go-000093 | 93 | sha256:27679561e8f1a6c6df734b1d324cada8a8cfc7c518fd784211662031421b85ac | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Ribosomal_uL5_C, Ribosomal_uL5_N that are essential for its biological function; 2. The protein should belong to Ribosomal_uL5, Ribosomal_uL5 that shares evolutionary origin and fun... | MSSEKAQNPMRELRIQKLVLNISVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRQFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYELRRRNFSETGNFGFGISEHIDLGIKYDPSIGIYGMDFYCCMTRPGERVAKRRRCKSRIGASHRITREETIRWFKQRFDGIVR | 173 | [
{
"id": "GO:0003735",
"name": "structural constituent of ribosome "
}
] | [
{
"id": "IPR022803",
"name": "Ribosomal_uL5_dom_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 2,
"end": 173
},
{
"id": "IPR031309",
"name": "Ribosomal_uL5_C",
"type": "DOMAIN",
"begin": 65,
"end": 152
},
{
"id": "IPR002132",
"name": "Ribosomal_uL5",
"typ... |
ipr_go-000094 | 94 | sha256:5e850aa2a567f0ef5f34a40fa5df7ed6666298024bf5e4a4184e8725ce2b1ae0 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Ribosomal_uL18_C_euk that are essential for its biological function; 2. The protein should belong to Rbsml_uL18_euk/arc, Rbsml_uL18_euk/arc, Rbsml_uL18_euk/arc, Rbsml_uL18_euk/arc, ... | MAFHKLVKNSAYYSRFQTKFKRRRQGKTDYYARKRLITQAKNKYNAPKYRLVVRFTNRDIITQMVTSEINGDKIFAAAYSHELRAYGINHGLTNWAAAYATGLLLARRVLAKLGLDKTFTGVEEPNGEYTLTEAAETEDGERRPFKAILDVGLARTSTGARVFGVMKGASDGGIFIPHSENRFPGYDIETEELDTEVLKKYIYGGHVAEYMETLADDDEERYKSQFVKYIEDDVEADSLEELYAEAHKQIRADPFRKYVSDAPKKSKEEWKAESLKYKKAKLSREERKARVEAKIKQLLAEQDE | 304 | [
{
"id": "GO:0008097",
"name": "5S rRNA binding "
},
{
"id": "GO:0003735",
"name": " structural constituent of ribosome "
}
] | [
{
"id": "IPR005485",
"name": "Rbsml_uL18_euk/arc",
"type": "FAMILY",
"begin": 1,
"end": 300
},
{
"id": "IPR025607",
"name": "Ribosomal_uL18_C_euk",
"type": "DOMAIN",
"begin": 239,
"end": 300
},
{
"id": "IPR005485",
"name": "Rbsml_uL18_euk/arc",
"type": "FA... |
ipr_go-000095 | 95 | sha256:d4e7707c323262208b48fc591ac398ecb437296b7ae5143354262910f5bfb2c8 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Triabi/Procalin that shares evolutionary origin and functional similarity; 2. The protein should be classified within Calycin, Calycin sharing conserved structural features; 3. The protein mu... | MKTILAVIFFGILAFAFADYPSIPKCTHPPAMANFNQKKFLEGKWYVTKAKHGSNSTVCREYRAKTKGNDQILVGDGYYSFNGGTFYFTVRCKRLPNKEVQKPLQFTCTQKSPDDPSKMFKFQLEVTILDTDYANYAVMYRCVQFPEELGSHFEDNTLLLHRKLDQLVDENLIERKLKLSLPSFKSRDDVVEGCRELPSKKKKTKP | 206 | [
{
"id": "GO:0090729",
"name": "toxin activity "
}
] | [
{
"id": "IPR012674",
"name": "Calycin",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 25,
"end": 196
},
{
"id": "IPR005657",
"name": "Triabi/Procalin",
"type": "FAMILY",
"begin": 24,
"end": 165
},
{
"id": "IPR012674",
"name": "Calycin",
"type": "HOMOLOGOUS_SU... |
ipr_go-000096 | 96 | sha256:201194063bbd87eee2e0a624461e81187d6b69f5c23e2848bc15a2d67e3af2da | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Triabi/Procalin that shares evolutionary origin and functional similarity; 2. The protein should be classified within Calycin, Calycin sharing conserved structural features; 3. The protein mu... | MKTILAVIFFGILAFAFADYPSIENCTHPPAMANFNQKKFLEGKWYVTKAKHGSNSTVCREYRAKTKGNDQILVGDGYYSFNGGTFYFTVRCKRLPNKEVQKPLQFTCTQKSTDDPSKMFKFQLEVTILDTDYANYAVMYRCVQFPEQLGSHFEDNTLLLHRNPDQLVDENQVERKLNLSFDSFRSREDVVDGCPKLPSKKKNKAS | 206 | [
{
"id": "GO:0090729",
"name": "toxin activity "
}
] | [
{
"id": "IPR012674",
"name": "Calycin",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 25,
"end": 200
},
{
"id": "IPR005657",
"name": "Triabi/Procalin",
"type": "FAMILY",
"begin": 22,
"end": 164
},
{
"id": "IPR012674",
"name": "Calycin",
"type": "HOMOLOGOUS_SU... |
ipr_go-000097 | 97 | sha256:5bad7e65801ec8cb99f507e9a58146ea70fefa83160d8597748c30f9b3364a8a | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more UDP-Glc/GDP-Man_DH_C, UDP-Glc/GDP-Man_DH_dimer, UDP-Glc/GDP-Man_DH_C, UDP-Glc/GDP-Man_DH_N that are essential for its biological function; 2. The protein should belong to UDP_ManNAc... | MEKEKGEEKMNDSRKITVIGLGYVGLPLAIHFAERGYNVVGLDKDKRKIERIEKGDSYIPDVSSNVLKDLVQNKQLVVYTPHTGIEEFQNSEYVIVTVPTPINKQKEPDLSALIAASHYIKQNLQAGQTFIFESSTYPGTLEEVIIPIIAQSGKEVGKDYYIGYSPERIDPANQQYTVQTIPKVISGQTERCKQQVQKLYSTIFDTVVPVSSPKVAEMCKLFENIQRLVNISLVNELNILCEKLGIDFREALEAAATKPFGFTPYWPGPGIGGHCIPVDPLYFQWKARQLGQSSQLIEVAHMINEKMPQQIVTQVKELSA... | 423 | [
{
"id": "GO:0051287",
"name": "NAD binding "
},
{
"id": "GO:0016628",
"name": " oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor "
},
{
"id": "GO:0003979",
"name": " UDP-glucose 6-dehydrogenase activity "
}
] | [
{
"id": "IPR028359",
"name": "UDP_ManNAc/GlcNAc_DH",
"type": "FAMILY",
"begin": 4,
"end": 423
},
{
"id": "IPR014027",
"name": "UDP-Glc/GDP-Man_DH_C",
"type": "DOMAIN",
"begin": 326,
"end": 420
},
{
"id": "IPR008927",
"name": "6-PGluconate_DH-like_C_sf",
"t... |
ipr_go-000098 | 98 | sha256:e3d3f83c429cf0df589c86b99b85a398b28dc176df1b3736b702f519a3840711 | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Endo_G_ENPP1-like_dom, Endo_G_ENPP1-like_dom that are essential for its biological function; 2. The protein should belong to Non-specific_endonuclease that shares evolutionary origi... | MSSFFLSISPLVLALFHVVVQVCSQSCQVAISELQSERKVIILNSDKRSLKQPSNGKYSWKSGESIYFICGKDLKTLTCSPSSINAKRFDCVKPPDVTERDINRECNGKSSKTFQMGFRASGGLFVPYYELCYLMDTCSVSHVKHRLLGASFGGVSGTREKSFQSFVCPGLRYNTHYTQASQKQPDPRFYFQRGHLFPDRDAPVFAWKLATYSYGNCVPQWNTINSEGGNWWTLEYLVFKYAQQTPNTEYTIYDGVLYDPRNKQYLAKQEKKIEIPVWFWKVVTNQTHVLKVFFVSHNLKGTKQTFCNTNRCVNDRAKGT... | 364 | [
{
"id": "GO:1990238",
"name": "double-stranded DNA endonuclease activity "
},
{
"id": "GO:0046872",
"name": " metal ion binding "
},
{
"id": "GO:0003676",
"name": " nucleic acid binding "
},
{
"id": "GO:0004521",
"name": " RNA endonuclease activity "
},
{
"id": "G... | [
{
"id": "IPR001604",
"name": "Endo_G_ENPP1-like_dom",
"type": "DOMAIN",
"begin": 125,
"end": 335
},
{
"id": "IPR040255",
"name": "Non-specific_endonuclease",
"type": "FAMILY",
"begin": 9,
"end": 298
},
{
"id": "IPR044929",
"name": "DNA/RNA_non-sp_Endonuclease_... |
ipr_go-000099 | 99 | sha256:e417fd3e45a20616417510986b5e6db769ec3af5bcd579579da746dd36cb608b | Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Tscrpt_reg_HTH_GntR, Tscrpt_reg_HTH_GntR, Tscrpt_reg_HTH_GntR, Tscrpt_reg_HTH_GntR that are essential for its biological function; 2. The protein should be classified within WH_DNA-... | MTELGDWVSIDPDSDKPLFDQLRVQIIDGIRDGRLSPGTRLPTVRELATHVGLAVNTVARSYRELEAAGVLETRGRFGTFVARADPADAAMAAAANSFAEAARSLGISRDDALRYIESALD | 121 | [
{
"id": "GO:0003677",
"name": "DNA binding "
},
{
"id": "GO:0003700",
"name": " DNA-binding transcription factor activity "
}
] | [
{
"id": "IPR000524",
"name": "Tscrpt_reg_HTH_GntR",
"type": "DOMAIN",
"begin": 22,
"end": 81
},
{
"id": "IPR036390",
"name": "WH_DNA-bd_sf",
"type": "HOMOLOGOUS_SUPERFAMILY",
"begin": 11,
"end": 91
},
{
"id": "IPR000524",
"name": "Tscrpt_reg_HTH_GntR",
"ty... |
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