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atrial fibrillation ( af ) is the most common sustained arrhythmia in western countries , with an estimated 30 million patients affected by 2050 across united states and europe alone .
atrial fibrillation has a significant impact on morbidity mainly related to symptoms , heart failure , and thromboembolic events and ... | atrial fibrillation
( af ) can be cured by pulmonary vein antrum
isolation ( pvai ) in a substantial proportion of
patients .
the high efficacy of pvai is partially
undermined by a small but concrete
periprocedural ris... |
breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women worldwide , accounting for 23% ( 1.38 million ) of the total new cancer cases and 14% ( 458,400 ) of the total cancer deaths in 2008 . about half of the breast cancer cases and 60% of the deaths are estimated to occur i... | breast cancer is the major cause of cancer morbidity and mortality between women in the world .
metals involved in environmental toxicology are closely related to tumor growth and cancer . on the other hand ,
some metals such as selenium have anticarcinogenic properties .
the aim of this study is to determine the... |
in the neonatal intensive care unit ( nicu ) population , hyponatremia is the most frequent encountered water and salt abnormality . with its broad differential diagnosis ,
the most frequent causes are renal salt loosing through an immature kidney and the use of drugs such as diuretics .
hypertension , however , is... | objective . to report the irreversible severe neurological symptoms following the hyponatremic hypertensive syndrome ( hhs ) in an infant after umbilical arterial catheterization
. design .
case report with review of the literature . setting . neonatal intensive care unit at a tertiary care children 's hospital . p... |
the first requirements of the no child left behind act ( nclb ) , which became law in 2002 , led every state to evaluate the adequate yearly progress ( ayp ) of students in math and language arts based on specific content standards in those subjects .
assessment requirements extended ( by statute , if not yet in prac... | science education in the united states will increasingly be driven by testing and accountability requirements , such as those mandated by the no child left behind act , which rely heavily on learning outcomes , or
standards , that are currently developed on a state - by - state basis . those standards , in turn , dr... |
traction exerted by the posterior hyaloid has been implicated in the pathogenesis of several conditions such as proliferative vitreoretinopathy ( pvr ) , proliferative diabetic retinopathy ( pdr ) , penetrating eye trauma and macular holes .
therefore the surgical goal of any vitrectomy should be posterior hyaloid se... | adequate visualization and identification of the posterior hyaloid , epiretinal membranes and the internal limiting membrane are of paramount importance in modern vitreoretinal surgery .
chromovitrectomy is a term used for describing the vital dyes use in order to stain these transparent tissues and facilitate their... |
atherosclerosis is a pathological process that takes place in the major arteries and represents one of the causes of myocardial infarction ( mi ) , ischemic stroke , and peripheral artery disease .
atherosclerosis , a multifactorial condition determined by environmental as well as genetic factors , has a strong infla... | coronary artery inflammation is a critical process in the pathogenesis of myocardial infarction ( mi ) .
the chemokine ccl5/rantes ( regulated upon activation , normal t cells expressed and secreted ) is expressed in advanced atherosclerotic lesions .
functional polymorphisms of the rantes gene can , therefore , be... |
the advent of antenatal ultrasound has allowed the diagnosis of conditions like large neck masses affecting the fetus which can compromise the airway after delivery . fetal magnetic resonance imaging ( mri )
has helped in better delineation and planning for perinatal intervention which will improve the survival of th... | ex - utero intrapartum treatment ( exit ) is performed for fetuses diagnosed with large neck masses .
a case report of a fetus diagnosed with a large cystic hygroma and cord around the neck who was delivered by exit is presented .
the airway challenges and optimal positioning is discussed . |
supplementary material is available for this article at 10.1007/s13659 - 012 - 0035-y and is accessible for authorized users .
| solenostemon scutellarioides is a commercially important ornamental plant . in present study
, it was attempted to establish a protocol for high frequency in vitro regeneration of s. scutellarioides .
caulogenesis was found to be significant in solid ms medium supplemented with 0.5 mg dm3 bap .
combination of ga3... |
tomato ( solanum lycopersicum ) is one of the most important vegetable crops cultivated worldwide .
tomato has a diploid ( 2n = 2x = 24 ) and relatively compact genome of approximately 950 mb .
genetic linkage maps of tomato have been created by crossing cultivated tomato ( s. lycopersicum ) with several wild rel... | a total of 93,682 bac - end sequences ( bess ) were generated from a dwarf model tomato , cv .
micro - tom . after removing repetitive sequences ,
the bess were similarity searched against the reference tomato genome of a standard cultivar ,
heinz 1706 . by referring to the heinz 1706 physical map and by elimi... |
the innate immune system or the nonspecific immune system is the first and the oldest line of defense in organisms [ 1 , 2 ] .
it was the most dominant form of immunity before the evolution of the more sophisticated adaptive immunity .
it is comprised of various mechanisms which are responsible for rapid defense of... | lactoferrin is a multifunctional , iron - binding glycoprotein which displays a wide array of modes of action to execute its primary antimicrobial function .
it contains various antimicrobial peptides which are released upon its hydrolysis by proteases .
these peptides display a similarity with the antimicrobial ca... |
aspirin - exacerbated respiratory disease ( aerd ) is a syndrome characterized by chronic hyperplastic rhinosinusitis , nasal polyposis , asthma , and aspirin sensitivity , as described in 1922 by szczeklik et al .
[ 1 , 2 ] . the prevalence of aerd is variable ; stevenson and szczeklik reported in 2006 that aerd occ... | aspirin exacerbated respiratory disease ( aerd ) is characterized by chronic hyperplastic rhinosinusitis , nasal polyposis , asthma , and aspirin sensitivity .
the mechanisms which produce these manifestations of intolerance are not fully defined , current research focuses on cyclooxygenase 1 ( cox-1 ) inhibition , m... |
traditionally , students learned in the classroom through interaction with the teachers , which required his physical presence and confidence in asking questions to clear his doubts
. many students may not take part in the discussion openly due to peer pressure and fear of asking a question that may appear silly and ... | background : although lecture handouts are commonly given to students during theory lectures , students perception , as well as their performance , can vary depending on the type of handouts they receive for information processing.methodology:this is a quasi - experimental study involving 6th semester medical students ... |
the cell must generally define an axis , localize fate determinants , and coordinately orient the mitotic spindle .
both plant and animal cells must accomplish these tasks , but unlike animal cells , plant cells are surrounded by a cell wall that impedes cell movement . in most plant cell types ,
the future divisio... | like animals , plants use asymmetric cell divisions to create pattern and diversity .
due to a rigid cell wall and lack of cell migrations , these asymmetric divisions incur the additional constraints of being locked into their initial orientations
. how do plants specify and carry out asymmetric divisions ?
inte... |
the importance of cd8 + t cells in viral clearance has been established in several viral models , including the nonhuman primate model of aids , in which depletion of cd8 + t cells resulted in the inability to clear infection [ 2 , 3 ] . several other evidences demonstrated the importance of the cd8 + t cell responses ... | cd8 + t cells are an essential component of an effective host immune response to tumors and viral infections .
genetic immunization is particularly suitable for inducing ctl responses , because the encoded proteins enter the mhc class i processing pathway through either transgene expression or cross - presentation . ... |
my introduction to research occurred in the summer of 1968 , when , as a third - year undergraduate student of biochemistry , i started to work with kai simons in the department of serology and bacteriology at the university of helsinki .
this would likely not have happened had he not been the older brother of my gir... | the fluid mosaic model for biological membranes was formulated 40 years ago .
ten years later endosomes were discovered as important prelysosomal organelles . at the outset of my research career ,
i was fortunate to witness both these turning points in biochemistry and cell biology from close up , and to participat... |
over 50 million women who live in areas of high malaria transmission become pregnant every year , and thousands of these women die .
women in their first and second pregnancies are at particular risk of infection with plasmodium falciparum , which is a major risk factor for maternal and foetal mortality and is implic... | pregnancy - associated malaria , a manifestation of severe malaria , is the cause of up to 200,000 infant deaths a year , through the effects of placental insufficiency leading to growth restriction and preterm delivery .
development of a vaccine is one strategy for control .
plasmodium falciparum - infected red bl... |
recent advances in implant dentistry have introduced a number of alternative
treatment options for the rehabilitation of partially and completely edentulous
patients . in recent years , focus has shifted to a great extent into the
restoration - driven approach for the placement of dental implants through a detail... | abstractbackgroundthe philosophy of a gradual transition to an implant retained prosthesis in
cases of full - mouth or extensive rehabilitation usually involves a staged
treatment concept . in this therapeutic approach
, the placement of implants
may sometimes be divided into phases . during a subsequent surgic... |
early repair is important because of risks of incarceration and strangulation of abdominal contents along with respiratory and cardiovascular compromise .
minimally invasive techniques have been useful for diagnosis and treatment of diaphragmatic hernias in both blunt and penetrating trauma .
we present the case of... | background : traumatic diaphragmatic hernias are a diagnostic and therapeutic challenge due to variable presentations .
early repair is important because of risks of incarceration and strangulation of abdominal contents along with respiratory and cardiovascular compromise .
minimally invasive techniques have been u... |
a central database was created in august 2002 for two cohorts of participants in the maestro project : 1 ) a younger group ( aged 18 years , n = 84 ) who had the assistance of the navigator as they graduated from pediatric care and 2 ) an older group ( aged 1925 years , n = 64 ) who were transferred to adult care witho... | objectives to determine whether a systems navigator service , the maestro project , could increase medical surveillance for young adults with type 1 diabetes who transfer from pediatric to adult care.research design and methods there were two cohorts of participants : 1 ) a younger group ( aged 18 years , n = 82 ) who ... |
immunization is one of the most cost - effective public health interventions and is largely responsible for the reduction of under-5 mortality rate .
vaccine preventable diseases have declined markedly worldwide since the introduction of the routine immunization program in 1978 , which was later upgraded in 1985 as t... | hypertrichosis is characterized by increased hair growth independent of androgen excess .
there are various causes of acquired localized hypertrichosis including chronic irritation and inflammation .
localised hypertrichosis following pentavalent vaccine has not been described previously in indian literature .
we... |
according to the report of who , approximately 450 million people suffer from mental or behavioral disorders like stress .
this amounts to 12.3% of the global burden of disease and is predicted to rise up to 15% by 2020 .
it is estimated that 7590% of visits to primary care physicians are related to stress either a... | background . the leaves of pandanus odoratissimus linn have been widely used in ayurveda to treat a variety of common and stress related disorders . in the present investigation , hydroethanol extract of leaves of pandanus odoratissimus linn ( lepo ) were evaluated for antistress activity in normal and stress induced m... |
a shared understanding of a patient s status between physicians , the patient , and caregivers is important in shared decision - making . not only can it reduce the discrepancy in expectations regarding treatment objectives
precise awareness of disease status , i.e. , shared understanding of cancer stages between can... | purposemany end - of - life care studies are based on the assumption that there is a shared definition of language concerning the stage of cancer . however , studies suggest that patients and their families often misperceive patients cancer stages and prognoses .
discrimination between advanced cancer and terminal ca... |
acquired perforating dermatoses ( apd ) is a group of rare chronic persisting dermatological disorders with poor treatment outcomes , characterized by transepidermal elimination in which collagen , elastic tissue or necrotic connective tissue from the dermis is extruded to the exterior with minimal disruption of surrou... | acquired perforating dermatosis ( apd ) is a rare disorder characterized by transepidermal elimination of contents from dermis with minimal disruption of surrounding structures , believed to be due to altered expression of dermal proteins .
its occurrence in patients with systemic mycosis has never been reported .
... |
gross alpha / beta activity measurements are widely applied as a screening technique in many fields ( e.g. environmental monitoring , industrial applications ) .
water intended for drinking purposes has to be analysed first for gross alpha / beta activity according to national and international standards and recommen... | an interlaboratory comparison was organised by jrc - irmm among environmental radioactivity monitoring laboratories for the determination of gross alpha / beta activity concentration in drinking water .
independent standard methods were used for the reference value determination .
the performance of participating l... |
recently , the health care community has recognised the importance of using qol measurement as an essential component of a treatment modality 's efficacy . at every stage of disease
, treatment choices may involve modalities that differ in side effects and impact upon qol .
quality - of - life assessment can be hel... | backgroundthis paper describes the development of a new quality of life instrument in advanced cancer patients receiving palliative care.methodsthe palliative care quality of life instrument incorporates six multi - item and one single - item scale .
the questionnaire was completed at baseline and one - week after . ... |
methicillin - resistant staphylococcus aureus ( mrsa ) is a common and important cause of infection in the intensive care unit ( icu ) setting .
the colonizing bacterial strains may serve as endogenous reservoirs for overt clinical infections or may spread to other patients .
several studies have demonstrated a lin... | abstractmethicillin - resistant staphylococcus aureus ( mrsa ) is a common and important cause of colonization and infection in medical intensive care units ( icu ) .
the aim of this study was to assess association factors between mrsa nasal colonization and subsequent infections in medical icu patients by clinical i... |
extended surgery is necessary to perform curative resection of gastric cancer with hepatic or / and pancreatic invasion .
the value of extended organ resection for advanced gastric cancer has been debated for many years .
the potential advantage of extended resection for t4 gastric cancer is necessary to improve th... | a 64-year - old man was transferred to our division with a suspicion of gastric cancer .
computed tomography showed widespread irregular thickening of the stomach walls close to the liver and pancreas .
gastrointestinal fiberscopy showed a type 5 tumor in the upper to lower stomach , histologically diagnosed as tub... |
giemsa dark and light bands are generally thought to correspond to gc - poor and gc - rich regions , respectively .
giemsa light bands are gene - rich and contain most housekeeping genes as well as a large number of cpg islands , whereas giemsa dark bands are gene - poor and preferentially contain tissue - specific g... | chromosomal fragile sites ( fss ) are loci where gaps and breaks may occur and are preferential integration targets for some viruses , for example , hepatitis b , epstein - barr virus , hpv16 , hpv18 , and mlv vectors . however , the integration of the human immunodeficiency virus ( hiv ) in giemsa bands and in fss is ... |
molecules that target and inhibit
v3 , v5 , and 51 integrins have
generated great interest
because of the role of these receptors in mediating angiogenesis and
metastasis .
attempts to increase the binding affinity and hence the
efficacy of integrin inhibitors by dimerization have been marginally
effectiv... | |
paramedics are frequently required to perform tracheal intubation , a potentially life - saving manoeuvre in severely ill patients , in the prehospital setting .
it is a difficult skill to acquire and to maintain , especially with limited training opportunities .
simulation training is an essential educational stra... | background and aims : glidescope video laryngoscope ( gvl ) and intubating laryngeal mask airway ( i - lma ) may be used to facilitate intubation and secure the airway in patients with normal and abnormal airways .
the aim of this study was to evaluate whether ( gvl ) and ( i - lma ) facilitate and improve the trache... |
precise measurement of the anterior chamber is important in many aspects of ophthalmology , such as assessing glaucoma risk [ 1 , 2 ] and surgical planning and intraocular lens ( iol ) power calculation [ 3 , 4 ] .
previous studies have focused on the measurement of anterior chamber depth ( acd ) or the anterior cham... | purpose . to evaluate the anterior chamber volume in cataract patients with swept - source optical coherence tomography ( ss - oct ) and its influencing factors
. methods .
anterior chamber volume of 92 cataract patients was evaluated with ss - oct in this cross - sectional study .
univariate analyses and multipl... |
blue nevus is considered a benign lesion that only in rare cases may progress into melanoma .
the term malignant blue nevus includes both a melanoma that arose within a common or a cellular blue nevus or a de novo melanoma simulating a blue nevus .
a peculiar type of blue nevus is the so - called large plaque typ... | the term large plaque type blue nevus with subcutaneous cellular nodules ( lptbn - sn ) refers to a huge blue nevus , usually located on the trunk , that develops subcutaneous nodules many years after the lesion has appeared .
the potential malignancy of an lptbn - sn was only discovered in 2012.we report the case of... |
the antibiotic resistance provides a great therapeutical and economic burden in the treatment of infectious diseases and it may threaten the success of antimicrobial chemotherapy .
the disproportion between the slow development of new drugs and the fast emergence of resistant strains necessitates the development and ... | the essential oil ( eo ) from salvia sclarea was shown to increase the susceptibility of methicillin resistant staphylococcus epidermidis ( mrse ) isolates to oxacillin .
the purpose of this study was to investigate the effect of eo from s. sclarea on expression of meca gene of mrse carrying different types of staphy... |
a clinical audit can identify activities that should or should not be performed in clinical settings ( 1 ) .
it not only improves care quality but also helps nurses to acquire and use the knowledge , skills , and attitudes necessary for creating a meaningful , productive , and satisfying working environment ( 2 ) . t... | background : although using the nursing process improves nursing care quality , few studies have evaluated nursing performance in accordance with nursing process steps either nationally or internationally.objectives:this study aimed to audit nursing care based on a nursing process model.patients and methods : this was ... |
endodontic surgery has advanced in recent years to increase the clinician 's ability to achieve more predictably successful clinical outcomes .
the properties of a root - end filling material are very critical in determining the success of periradicular surgery .
, to address the shortcomings of commonly used root ... | introduction : the present study is designed to assess the apical seal obtained after root end cavity irrigation with mtad and retrograde filling with mineral trioxide aggregate ( mta ) and biodentine.materials and methods : sixty extracted maxillary central incisors were instrumented and obturated .
apical 3 mm of a... |
during the last decades , we have witnessed a global epidemic of obesity . a sedentary lifestyle and an atherogenic diet , along with genetic predisposition , are probably the driving forces of this problem . according to the last national health and nutrition examination survey ( nhanes ) ,
obesity , particularly ab... | the metabolic syndrome ( ms ) and chronic kidney disease ( ckd ) have both become global public health problems , with increasing social and economic impact due to their high prevalence and remarkable impact on morbidity and mortality .
the causality between ms and ckd , and its clinical implications , still does rem... |
the theory of fetal origins of adult disease ( foad ) proposed by barker et al .
( 1986 ) claims that physiological changes during intrauterine development would promote the restriction of development , as well as ultrastructural and physiological changes that would predispose to the early development of cardiovascul... | objective . to evaluate the expression of inflammatory markers in experimental renal failure after fetal programming .
methods .
the offspring aged two and five months were divided into four groups : cc ( control dams , control offspring ) ; dc ( diabetic dams , control offspring ) ; cfa ( control dams , folic acid... |
calpain ( ec 3.4.22.17 ) is a ca - dependent cysteine protease first isolated in 1978 , with a ph optimum between 7.0 and 8.0 .
there are at least 15 distinct calpain genes present in the human genome and several have a number of isoforms ( up to 10 ) . along with the atp - dependent proteasome , calpain appears to b... | backgroundinhibitors of the protease calpain are known to have selectively toxic effects on plasmodium falciparum .
the enzyme has a natural inhibitor calpastatin and in eukaryotes is responsible for turnover of proteins containing short sequences enriched in certain amino acids ( pest sequences ) .
the genome of p... |
the strong association between abdominal fat and increased risk of cardio - metabolic risk suggests that measures of central fat distribution such as waist circumference ( wc ) and whr may be better than measures of general obesity , such as bmi , in predicting type 2 diabetes
. this may be particularly important i... | aims / hypothesisthe aim of this study was to examine whether waist circumference ( wc ) or whr improve diabetes prediction beyond body mass index in older men and women , and to define optimal cut - off points.methodsin this prospective study , non - diabetic men ( n = 3,519 ) and women ( n = 3,404 ) aged 6079 ye... |
the current application of physiologically based pharmacokinetic ( pbpk ) modeling in drug development was summarized by three industry representatives ( links to all presentations are provided in supplementary table 1 and a comprehensive meeting report is available online1 ) .
jan snoeys ( janssen ) provided an over... | under the remit of the ministerial industry strategy group ( misg ) , the association of the british pharmaceutical industry ( abpi ) and medicines and healthcare products regulatory agency ( mhra ) hosted a meeting to explore physiologically based pharmacokinetic modeling and simulation , focusing on the clinical comp... |
to extract sij from the experimentally accessible gij , we formally link ( 1 ) and ( 2 ) via ( 3){dxidxi=1dxidxj=k=1nxixkdxkdxjij}.
equation ( 3 ) is exact and the sum accounts for all network paths connecting i and j ( supplementary note s.i.1 - 2 ) .
it is of limited use , however , as it requires us to solve n c... | predicting physical and functional links between cellular components is a fundamental challenge of biology and network science .
yet , correlations , a ubiquitous input for biological link prediction , are affected by both direct and indirect effects , confounding our ability to identify true pairwise interactions . ... |
basal cell carcinoma ( bcc ) is the most common cutaneous malignancy , the most common human malignancy overall , and its incidence is increasing . for more than 80 years , convincing epidemiological evidence has linked sun exposure with skin cancer .
bcc is more frequent in patients with higher cumulative sun exposu... | basal cell carcinoma ( bcc ) is the most common human malignancy .
both epidemiological and direct evidence have established ultraviolet ( uv ) exposure from the sun as the most important risk factor for bcc development
. there has only been one randomized and controlled study to examine sunscreen 's role in the pr... |
alzheimer 's disease ( ad ) is the most common neurodegenerative disease , accounting for more than 50% of all dementia types .
its twice more common in females which could be due to increased longevity and sex difference in brain size .
women with alzheimer have lower endogenous estrogen level which lead to the hy... | alzheimer disease ( ad ) is a crippling neurodegenerative disorder .
it is more common in females after menopause .
estrogen probably has a protective role in cognitive decline .
large amount of research has been carried out to see the benefits of hormone replacement therapy with regards to alzheimer still its ne... |
changes in olfactory functions have been found in many neurodegenerative and psychiatric disorders , including parkinson s disease , alzheimer - type dementia , schizophrenia , obsessive compulsive disorder , and attention deficit / hyperactivity disorder ( adhd ) , as well as autism spectrum disorders ( asds).1,2 in ... | backgroundchanges in olfactory functions have been found in many neurodegenerative and psychiatric disorders , including autism spectrum disorders ( asds ) .
the aim of the present study was to evaluate the relationship between olfactory functions ( odor - detection thresholds , odor identification , and odor prefere... |
multi - wavelength observations of coronal mass ejections ( cmes ) can be successfully used to investigate the main physical plasma parameters of the solar corona . for the most energetic cme events , a forward fast - mode magnetohydrodynamic ( mhd ) shock
coronal shocks are thought to be driven by coronal mass eject... | the analysis of the spectral properties and dynamic evolution of a cme / shock event observed on november 1st 2003 in white - light by the lasco coronagraph and in the ultraviolet by the uvcs instrument operating aboard soho , has been performed to compute the properties of some important plasma parameters in the middl... |
when the hiv epidemic peaked in 1993 , aids was the leading cause of death among 25 - 44-year - old men and women and the eighth most common cause of death worldwide ( 1 ) . injection drug use ( idu ) and unprotected sex are considered as major risk factors for the acquisition of retroviral infection ( 2 - 4 ) , and mo... | background : this study was performed in response to the rapid propagation of hiv / aids across iran and its status in this region .
accordingly , an evidence - based program is required to combat this disease.objectives:the present study estimated the prevalence of hiv / aids in east azerbaijan ( population : 3,724,... |
it is a major cause of disability and higher health care costs in the world .
this clinical condition often results from vertebral injuries , intervertebral disc herniation , intervertebral foramen stenosis , or other disorders affecting the dorsal root ganglion ( drg ) or its near nerve root .
so far , to reveal t... | evidence has accumulated that reactive oxygen species and inflammation play crucial roles in the development of chronic pain , including radicular low back pain .
nonsteroid anti - inflammatory drugs ( nsaids ) , for example , salicylic acid , aspirin , provided analgesic effects in various types of pain .
however ... |
the use of chemotherapeutics to treat malignancies is rooted in the use of mustard gas during the world wars .
sinking of the uss john harvey carrying a cargo of mustard bombs in the port city of bari , italy , in 1943 released the toxic payload and exposed survivors and residents to nitrogen mustard gas . within 34 ... | chemotherapy , irradiation , and other agents are widely used to target the process of cell division in neoplastic cells . however , while these therapies are effective against most cancers , the high proliferative rate of the cells of the hematopoietic system that produce billions of blood cells needed daily throughou... |
depressive disorders are characterized by sustained and persistent low mood with loss of interest , easy fatigability , disturbed sleep , decreased concentration and suicidal thoughts .
anxiety disorders have sustained feeling of impending threat with disturbed autonomic system ( ans ) functions . according to nation... | background : 5httlpr polymorphism ( 5- hydroxy tryptamine transporter linked promoter region polymorphism )
is the most widely studied genetic variant in psychiatry .
the present study is a modest effort at ascertaining
the role of 5ht transporter linked promoter region polymorphism ( 5httlpr ) in anxiety and dep... |
hypoxic - ischemic encephalopathy ( hie ) is a serious brain injury due to birth asphyxia [ 1 , 2 ] .
hie has a variety of perinatal causes of interrupted uterine and fetal blood flow and/or hypoxia , such as uterine rupture , placental abruption , and cord prolapse .
however , most often , the exact timing and und... | despite major advances in monitoring technology and knowledge of fetal and neonatal pathophysiology , neonatal hypoxic - ischemic encephalopathy ( hie ) remains one of the main causes of severe adverse neurological outcome in children . until recently
, there were no therapies other than supportive measures . over th... |
its prevalence ranges from 1% to 3% in the western world.1,2 genetic and enviromental factors are relevant in the pathogenesis of psoriasis.3 in psoriasis , the inflammatory cytokine network is deregulated , leading to the excessive release of proinflammatory mediators from immune cells and increase in the proliferatio... | chronic plaque psoriasis presents clinically as an inflammatory disease of the skin , which is often associated with comorbidities and responsible for a poor quality of life .
it can widely vary among patients because of different age of onset , type of symptoms , areas of involvement , and disease severity .
the c... |
takayasu 's arteritis ( ta ) and crohn 's disease ( cd ) are chronic inflammatory granulomatous autoimmune disorders that lead to characteristic manifestations .
cd predominantly affects the gastrointestinal tract , and various hypotheses concerning the underlying pathology have been proposed , ranging from environme... | crohn 's disease ( cd ) and takayasu 's arteritis ( ta ) are inflammatory granulomatous autoimmune disorders . simultaneous occurrence of cd and ta in the same individual is rare .
we report two cases treated with biologic agents .
case 1 : a 16-year - old male presented with abdominal pain , nausea , vomiting .
... |
ingestion of caustic agents leads to injuries in
the esophagus , pharynx , larynx , and mouth , which often lead to death or other adverse
effects on the gastrointestinal and respiratory tracts .
ingestion of caustic agents are frequently reported in children , especially when children
start to walk or crawl . ... | introduction : caustic ingestion that occurs accidently is one
of the most common problems in children .
methods : this systematic review has been performed by
searching the databases including science direct , proquest , google scholar , and pubmed .
a
strategic search was performed with keywords including ... |
cerebrospinal fluid ( csf ) leaks complicate operations of the cranial base , particularly those involving the anterior skull base ( asb ) .
kassam et al reported on their experience with almost 800 asb procedures and reported a postoperative csf leak , the most common complication they encountered , in 15.9% of pati... | this study assesses the efficacy of preoperative lumbar drain ( ld ) placement prior to elective open cranial and endoscopic anterior skull base ( asb ) surgery in reducing postoperative cerebrospinal fluid ( csf ) leak .
a retrospective review of 93 patients who underwent ld placement at our institution between 2006... |
neuroleptic malignant syndrome ( nms ) is a rare but the most severe side effect associated mostly with the use of antipsychotics.1 the most frequent signs and symptoms of nms include fever , muscle rigidity , autonomic dysfunction ( eg , tachycardia , labile blood pressure , tachypnea ) , confused mental state , and c... | here , we report a female patient developing neuroleptic malignant syndrome following the use of a combination of clozapine and haloperidol .
subsequently , the patient presented withdrawal effects after an abrupt discontinuation of clozapine .
psychiatrists not aware of possible clozapine - withdrawal effects may ... |
high caffeine containing energy drinks are widely consumed by adolescents . due to the risk - taking behavior of adolescents and their lack of education on the negative effects of caffeine , cases of toxicity due to the consumption of energy drinks are likely to continue to increase [ 13 ] .
in particular , there is ... | prenatal caffeine exposure adversely affects the development of the reproductive organs of male rat offspring .
thus , it is conceivable that peripubertal caffeine exposure would also influence physiologic gonadal changes and function during this critical period for sexual maturation .
this study investigated the i... |
menopause is associated with an increase in intra - abdominal fat , which is considered a major risk factor of atherosclerotic cardiovascular disease ( cvd ) . however
, whether an increased risk of cvd in postmenopausal women is due to altered body composition , changes in reproductive hormones , or some other physi... | we hypothesized that soy isoflavones would attenuate the anticipated increase in androidal fat mass in postmenopausal women during the 36-month treatment , and thereby favorably modify the circulating cardiometabolic risk factors : triacylglycerol , ldl - c , hdl - c , glucose , insulin , uric acid , c - reactive pro... |
polyneuropathy , organomegaly , endocrinopathy , monoclonal gammopathy , skin changes ( poems ) syndrome causes the following clinical manifestations : ( the initial letters of which form the word poems ) as well as extravascular volume overload , erythrocytosis / thrombocytosis , osteosclerotic lesions , and elevated ... | key clinical messagepolyneuropathy , organomegaly , endocrinopathy , monoclonal gammopathy , skin changes ( poems ) syndrome is a rare plasma cell disorder that causes a paraneoplastic syndrome .
we report the first case of poems syndrome with synchronous breast cancer .
the patient was at risk of being misdiagnose... |
serotonin transporter gene ( slc6a4 , solute carrier family 6 , member 4 ) encodes an integral plasma membrane protein that plays a major role in the regulation of serotonin neurotransmission ( 1 ) .
it has been widely recognized as the target sites of selective serotonin reuptake inhibitor ( ssris ) , which have bee... | there have been numerous studies on the association between 5-httlpr ( polymorphisms in the promoter region of the serotonin transporter gene ) and anxiety - related personality traits , with conflicting results . in this study , we administered korean version of the temperament and character inventory ( k - tci ) to a... |
spinal cord neoplasms are rare in the pediatric and adult patient population ; however , spinal neoplasms are less common in children compared with adults .
only 0.51% of the central nervous system ( cns ) neoplasms are located within the spinal cord . the vast majority ( 90% ) of spinal cord neoplasms
the rarity o... | abstractspinal cord neoplasms are rare lesions in children . most of the spinal cord neoplasms are astrocytomas . frequently the clinical symptoms are non - specific .
back pain is often the leading symptom .
diagnosis is often delayed .
magnetic resonance imaging is the imaging modality of choice .
preoperativ... |
chronic obstructive pulmonary disease ( copd ) is characterized by progressive and partially reversible airflow limitation , and it is among the leading causes of mortality worldwide.1 copd is a multicomponent disease , and patients present a range of comorbidities that have an impact on prognosis and may increase the ... | purposewe investigated the association between cognitive impairment and chronic obstructive pulmonary disease ( copd ) , taking into account demographic and clinical variables evaluated during routine practice.patients and methodswe performed a post hoc analysis of a cross - sectional study that included subjects with ... |
sepsis is a clinical syndrome that results from complex interaction between host and infectious agents and is characterized by systemic activation of multiple inflammatory pathways .
the pathophysiology of sepsis could be initiated by the outer membrane components of gram - negative and gram - positive organisms .
... | background and aims : sepsis is a complex rapidly progressive infectious disease that remain a major cause of morbidity and mortality in surgical patients and trauma victims .
edaravone a novel free radical scavenger was approved in 2001 in japan for treatment of acute cerebral and myocardial infarction . hence , in ... |
the major objectives of root canal therapy are removal of the pathologic pulp , shaping and cleaning of the root canal system , disinfection of the contaminated root canals and three dimensional obturation to prevent reinfection.1 the success of endodontic therapy depends on adequate access , thorough biomechanical pre... | background : to compare fracture resistance of endodontically treated teeth obturated with different resin - based adhesive sealers with a conventional obturation technique.materials and methods : a total of 60 single canaled teeth were divided into five groups .
the first group was taken as a negative control .
th... |
to provide a literature review of implant related complications from bilateral newcoloriris implantation ( kahn medical devices , panama city , panama ) .
a pubmed search of peer - reviewed ophthalmology journals for complications related to newcoloriris implants was performed .
including a recent case published by... | purpose : to provide a literature review of implant related complications from bilateral newcoloriris implantation ( kahn medical devices , panama city , panama).methods : a pubmed search of peer - reviewed ophthalmology journals for complications related to newcoloriris implants was performed.results:including a recen... |
the internal transcribed spacer 2 ( its2 ) of the nuclear rrna cistron is a widely used phylogenetic marker .
as its sequence evolves comparably fast , it is mainly used for low - level analyses .
the hallmarks , namely four helices with the third as the longest , have been found in detailed exemplary studies ( 1 )... | an increasing number of phylogenetic analyses are based on the internal transcribed spacer 2 ( its2 ) .
they mainly use the fast evolving sequence for low - level analyses .
when considering the highly conserved structure , the same marker could also be used for higher level phylogenies . furthermore
, structural... |
fetal malnutrition ( fm ) is a significant contributor to perinatal morbidity and mortality.123 it is a state of poor nutrition in - utero resulting from inadequate supply and/or utilization of nutrients1 leading to the fetus failing to acquire adequate amount of fat , subcutaneous tissues , and muscle mass during intr... | background : fetal malnutrition ( fm ) which describes the underweight / wasting seen in newborns is a significant contributor to perinatal morbidity and mortality and requires proper documentation .
the objective of this study was to assess the nutritional status of term newborns at birth using clinical assessment o... |
to determine the accuracy of the holladay 1 , hoffer q , sanders - retzlaff - kraff ( srk)/t , and srk ii iol power calculation formulas in patients with high myopia in a subset of indian population .
this study was conducted at sadguru netra chikitsalaya , chitrakoot , madhya pradesh , india .
all consecutive pati... | efficacy of intraocular lens power calculation formulas in a subset of indian myopic population . retrospectively reviewed 43 patients who underwent phacoemulsification with high axial length ( al ) ( > 24.5 mm , range 24.75 - 32.35 mm ) .
the power of the implanted intraocular lens ( iol ) was used to calculate the ... |
glycogenic hepatopathy ( gh ) was first identified at 1930 and it is characterized by elevated liver enzyme , hepatomegaly , and glycogen accumulation within hepatocytes and it can be found in patients with type i diabetes mellitus ( dm ) with poorly controlled blood sugar.1,2 clinically , gh has been known to have ben... | glycogenic hepatopathy ( gh ) is an uncommon cause of serum transaminase elevation in type i diabetes mellitus ( dm ) .
the clinical signs and symptoms of gh are nonspecific , and include abdominal discomfort , mild hepatomegaly , and transaminase elevation . in this report
we describe three cases of patients prese... |
mammalian cells , bacterial strains , and culture
conditions hela human cervix carcinoma cells ( atcc ccl-2 ) were
cultured in dmem plus glutamax ( amersham biosciences ) supplemented with 1%
sodium pyruvate ( amersham biosciences ) and 10% fetal calf serum .
l.
monocytogenes type strain egd ( bug 600 ) ... | septins are filament - forming gtpases implicated in several cellular
functions , including cytokinesis .
we previously showed that sept2 , sept9 , and
sept11 colocalize with several bacteria entering into mammalian non - phagocytic
cells , and sept2 was identified as essential for this process . here , we
... |
arrow injuries are an extinct form of injury in most parts of the developed world but are still seen , albeit infrequently in developing countries .
reports of penetrating injuries of the craniofacial region secondary to projectiles are few and far between .
we report the case of a patient who was attacked by a pro... | arrow injuries are an extinct form of injury in most parts of the developed world , but are still seen , albeit infrequently in developing countries .
reports of penetrating injuries of the craniofacial region secondary to projectiles are few and far between .
the morbidity - free outcome of surgical removal , in c... |
they are opportunistic and associated with some health - related infections ( 1 , 2 ) .
such bacterial infections , particularly in patients hospitalized at intensive care units , are very dangerous ( 3 ) .
in addition , colonization rates are rising among hospitalized patients , especially those hospitalized for a... | backgroundacinetobacter calcoaceticus baumannii ( acb ) complex are gram - negative opportunistic bacteria with low virulence properties .
their resistance to antibiotics has become a matter of concern in hospital infections.objectivesthe present study aimed to determine the prevalence and antimicrobial susceptibilit... |
ten years later , levels of serum tumor marker ca15 - 3 progressively increased until 2n although other serum tumor markers ( a - fetoprotein , carcinoembryonic antigen , carbohydrate antigen 19 - 9 ) were normal .
axial contrast - enhanced multislice ct scan showed a solitary and hypovascular 4-cm lesion located in ... | von meyenburg complexes ( vmc ) are a cluster of benign liver malformations including biliary cystic lesions , with congenital fibrocollagenous stroma .
this rare entity can mimick multiple secondary hepatic lesions .
we report a case of a 56-year - old woman who had multiples liver lesions 12 years after operation... |
chronic myelogenous leukemia ( cml ) is a malignant clonal disorder of hemopoietic stem cells characterized by abnormal proliferation and accumulation of immature granulocytes .
leukostasis is one of the complications of cml and is characterized by partial or total occlusion of microcirculation by aggregation of leuk... | chronic myelogenous leukemia ( cml ) is a malignant clonal disorder of hemopoietic stem cells characterized by abnormal proliferation and accumulation of immature granulocyte .
leukostasis is one of the complications of cml and is characterized by partial or total occlusion of microcirculation by aggregation of leuke... |
acute lung injury ( ali ) , induced by pneumonia , sepsis , multiple trauma , aspiration of gastric contents and severe burns , is a critical illness syndrome marked by excessive production of proinflammatory mediators , massive infiltration of leukocyte , and rapid alveolar injury , resulting in respiratory failure an... | the present study was carried out to investigate the effects and mechanisms of polydatin ( pd ) in septic mice .
the model of cecal ligation and puncture ( clp-)induced sepsis was employed .
pretreatment of mice with pd ( 15 , 45 , and 100 mg / kg ) dose - dependently reduced sepsis - induced mortality and lung in... |
the migration of an encircling silicone band through a rectus muscle is a rare postoperative complication associated with the scleral buckling procedure .
however , both kreis et al . and tan et al . have reported cases of this rare complication . here , we describe what we believe to be the first reported case o... | the migration of an encircling silicone band through a rectus muscle is a rare postoperative complication associated with scleral buckling surgery for retinal detachment . in this present study
, we describe what we believe to be the first reported case of a patient who experienced postoperative migration of an encir... |
the use of biomass as a source of energy used in heating systems , power and cogeneration plants or vehicle motors is forecast to grow considerably in the next decades ( nakicenovic and swart , 2000 ) .
bioenergy is promoted for several reasons , e.g. reducing the dependency on exhaustible fossil energy , greenhouse ... | the future bioenergy crop potential depends on ( 1 ) changes in the food system ( food demand , agricultural technology ) , ( 2 ) political stability and investment security , ( 3 ) biodiversity conservation , ( 4 ) avoidance of long carbon payback times from deforestation , and ( 5 ) energy crop yields . using a bioph... |
only 10 cases without predisposing factors such as arthropathy or infectious joint alterations have been described until now.[17 ] it is potentially serious injury that can be associated with concurrent injuries to ribs , lungs , spine , great vessels , or myocardium .
only a few case of patients treated surgically a... | traumatic manubriosternal dislocation is a rare lesion . in the literature ,
only a few case reports of patients treated surgically are published . in this case , we report an unstable posterior dislocation of the manubriosternal joint in a 50-year - old women caused by direct trauma .
an open reduction was perform... |
a 15-day - old female neonate patient was brought with history of a sudden onset proptosis of the left eye for three days .
ocular examination revealed an axial proptosis of the left eye with limited ocular movements in all directions [ fig . 1 ] .
systemic examination revealed no abnormalities except the presence ... | orbital cellulitis is a serious , yet uncommon infection in neonates .
it can result in significant sight and life threatening complications .
most commonly , it occurs secondarily as the result of a spread of infection from the sinuses .
orbital cellulitis , secondary to dental infection is rare .
we hereby re... |
leukocyte adhesion deficiency type i ( lad - i ) is a rare autosomal recessive disorder with usual described incidence of 1 in 1 million .
overall about 300 cases have been reported until date with very few cases in newborn .
lad - i is characterized by delayed separation of the umbilical cord at birth , persistent... | leukocyte adhesion deficiency type i is an extremely serious and rare form of congenital immunodeficiency with recurrent episodes of infection since neonatal period .
it is usually diagnosed in childhood , but if diagnosed early in neonatal period then definitive treatment can be instituted early with promising resul... |
insect samples were collected from preserved specimens of the insect museum at kangwon national university in chuncheon ( gangwon province , korea ) .
collected insects were surface sterilized in a 2% sodium hypochlorite solution for 3 min , rinsed with plenty of sterile distilled water , then dried using filter pape... | three penicillium species have been isolated from insect specimens in korea ; penicillium sp . , p. steckii , and p. polonicum .
penicillium sp .
( knu12 - 3 - 2 ) was isolated from lixus imperessiventris , while p. polonicum ( knu12 - 1 - 8 ) and penicillium steckii ( knu12 - 2 - 9 ) were isolated from muljarus ja... |
the protozoan pathogen , trypanosoma brucei , undergoes complex cycles of differentiation and multiplication in its vector , the tsetse fly , genus glossina . the infection is first established in the midgut and the trypanosomes migrate anteriorly from this stronghold on a tortuous journey to the paired salivary glands... | backgroundthe protozoan pathogen , trypanosoma brucei , undergoes complex cycles of differentiation and multiplication in its vector , the tsetse fly , genus glossina .
flies are refractory to infection and resistance mechanisms operate at a number of levels and timepoints . here
we have used highly conspicuous gre... |
patient 6 is a 62-year - old man from the town of mandal who was bitten by a tick ; onset of symptoms began 2 weeks later . at the end of may ,
the patient was dizzy and weak , had a headache , chills , and fever .
the antibody from serum sample profiles showed previous infection with herpes simplex and varicella z... | the first reported case of tickborne encephalitis ( tbe ) in norway occurred in 1997 . from 1997 to 2003 , from zero to two cases of human tbe have been diagnosed per year in norway , for a total of eight cases .
clinical tbe cases in dogs are not reported in norway . |
communicable disease control is a public health priority at the international level to prevent the spread of contagious diseases ( 1 , 2 ) .
the increase of emerging and re - emerging communicable diseases such as sars , multi drug resistance tuberculosis ( mdr tb ) , ebola and increasing information needs causes inc... | background : communicable disease reporting and surveillance system has poor infrastructure and supporters in most of countries . its quality improvement is a challenge and requires an accurate and efficient care and reporting systems at all levels to achieve new and simple models .
this study evaluates reporting sys... |
dry eye syndrome is a disorder of the ocular surface that is characterized by loss of natural function of the corneal and conjunctival epithelial barrier . moreover ,
cytomorphological studies have revealed microchanges in the epithelium comprising changes in size of surface cells and number of goblet cells as well a... | summarybackgrounda large number of artificial tears is widely used to treat dry eye symptoms . to test the efficacy of these drugs independent of individual parameters in vitro models are required . as described previously , we employed a reproducible in vitro cell culture system to evaluate the desiccation protection ... |
a variety of bacterial pathogens are responsible for causing urinary tract infections ( utis ) , but the most prominent are escherichia coli , enterococcus spp . ,
pseudomonas aeruginosa and mirabilis , klebsiella pneumoniae , candida albicans , enterobacter spp . , and coagulase - negative staphylococci .
however ... | urinary tract infections ( utis ) represent one of the most commonly acquired diseases among the general population as well as hospital in - patients , yet remain difficult to effectively and consistently treat .
high rates of recurrence , anatomic abnormalities , and functional disturbances of the urinary tract all ... |
however , it is also associated with variable post - operative consequences like pain , swelling and trismus .
corticosteroids are some of the most common pharmaceutical agents employed to manage these sequelae . of these
, methylprednisolone is a highly selective , intermediate acting , synthetic glucocorticostero... | aim and objectives : this study evaluated the efficacy of oral methylprednisolone and diclofenac sodium on post - operative sequelae after third molar surgery.settings and design : a randomized double - blind clinical trial was conducted ( with institutional and university approval for dissertation ) to evaluate the ef... |
we present a case that occurred at bunbury hospital where a kirschner wire ( k - wire ) has been propelled distally down the intramedullary canal of the ulna when it made contact with the drill . in both cases ,
ms r is a 68-year - old female who had a fall off a push bike and presented to the emergency department wi... | at bunbury regional hospital , we recently saw a case where kirschner wires ( k - wires ) , used during open reduction and internal fixation of olecranon , were propelled down the intramedullary canal intraoperatively .
the k - wire was only secured unicortically . from our experience
, we have developed steps to p... |
df of the bone is an extremely rare , lytic , locally aggressive but non - metastatic primary bone tumor .
histologically , df consists of wavy fibroblasts and abundant collagenous tissue , bears a close resemblance to a desmoid tumor of the soft tissues and exhibits a characteristic production of collagen fibers ( 1... | desmoplastic fibroma ( df ) is a benign , rare fibroblastic intraosseous neoplasm histologically resembling a desmoid soft tissue tumor .
although classified as benign , df frequently exhibits an aggressive behavior , has a moderate - to - high recurrence rate , and often causes pathological fractures and extensive b... |
transurethral resection of the prostate ( turp ) is considered the best option for treating benign prostatic enlargement ( bpe ) ; however , it is associated with significant bleeding . in recent years
, we have seen a gradual increase in life expectancy and , particularly in more developed countries , an increased i... | purposethulium vaporesection of the prostate ( thuvarp ) is a new and safe approach for patients receiving anticoagulant therapy in whom transurethral resection of the prostate ( turp ) may possess a high bleeding risk .
we aimed to demonstrate the efficacy and safety of thuvarp in patients receiving oral antiplatele... |
all subjects were recruited from patients ages 5 years to 17 years presenting to the pediatric clinic .
informed consent from parents was taken . to be enrolled , subjects had to have no ocular problems other than refractive error .
exclusion criteria were strabismus or amblyopia , any abnormalities of the disc or ... | purpose : to measure the peripapillary retinal nerve fiber layer ( rnfl ) thickness in normal indian pediatric population.subjects and methods:120 normal indian children ages 5 - 17 years presenting to the pediatric clinic were included in this observational cross - sectional study .
rnfl thickness was measured with ... |
for henry , the common presupposition that links classical philosophy with historical phenomenology from husserl and heidegger to merleau - ponty and levinas consists in the fact that they think the logos of phenomena as the logos of the world . to put it another way ,
for this reason , henry believes , they are no... | this essay explores the practical significance of michel henry s material phenomenology . commencing with an exposition of his most basic philosophical intuition , i.e. , his insight that transcendental affectivity is the primordial mode of revelation of our selfhood , the essay then brings to light how this intuitio... |
over the last decades numerous publications have highlighted the decline of serum testosterone levels in aging men .
this decline has been termed late - onset hypogonadism ( loh ) . rather than chronological age
per se , obesity , but also impaired general health , are the more common causes of low testosterone in ... | purposeto investigate the potential benefits of testosterone administration to elderly men ( > 65 years ) with late - onset hypogonadism ( loh ) in comparison with younger men and to assess the safety of testosterone administration to elderly men.materials and methodsa total of 561 hypogonadal men from two registry stu... |
haemophilus spp . generally colonize the upper respiratory tract and can cause infections such as bronchitis , sinusitis , epiglottitis , pneumonia and meningitis .
h. influenzae has been reported as a rare cause of genitourinary tract infection such as urinary tract infection , , , , , pyelonephritis , , prostatitis... | haemophilus species are known to colonize the upper respiratory tract and can cause infections .
however haemophilus influenzae has been rarely described as a cause of genitourinary tract infection .
we report a 44-year - old nonimmunocompromised japanese man with bacteremic pyelonephritis caused by a nontypable h.... |
iniencephaly is a rare , fatal neural tube defect ( ntd ) characterized by occipital bone defects at foramen magnum , fixed retroflexion of head , spinal dysmorphism , and lordosis of cervicothoracic vertebrae .
howkin and lawrie in 1939 classified iniencephaly into two types based on the presence or absence of encep... | iniencephaly is a rare form of neural tube defect with an incidence of 0.1 - 10 in 10,000 pregnancies .
it is characterized by the presence of occipital bone defects at foramen magnum , fixed retroflexion of head , spinal dysmorphism , and lordosis of cervicothoracic vertebrae .
it is usually associated with centra... |
this case describes the development of acute kidney injury following oral ingestion of 3,4-methylenedioxymethamphetamine ( ecstasy ) with histological demonstration of venous thrombosis .
a 22-year - old man presented with acute bilateral loin pain and was referred by his general practitioner for a urological consult... | the use of 3,4-methylenedioxymethamphetamine , also known as mdma or ecstasy , has been associated with vascular and end - organ damage .
this case report describes , with histological evidence , the development renal venous thrombosis presenting with acute kidney injury following oral ingestion of 3,4-methylenedioxy... |
currently , basalbolus insulin therapy is used to provide the insulin secretory patterns most physiologically similar to normal .
basalbolus therapy includes multiple daily injection ( mdi ) and continuous subcutaneous insulin infusion ( csii ) therapies .
the recent advent of rapidacting insulin analogs and longac... | abstractaims / introduction : the daily basal insulin doses / body weight and the daily basal insulin doses / total daily insulin doses of japanese type 1 diabetes mellitus patients are less than those of western type 1 diabetes mellitus patients .
it is known that western meals are richer in fat than japanese meal... |
left ventricular free wall rupture ( lvfwr ) is reported to occur in 2 - 6% of acute myocardial infarction ( mi ) cases .
lvfwr is presumed responsible for as much as 20 - 80% of infarct - related deaths.1 ) there is a history of previous mi in 25% of cases , lvfwr can often be the first presentation of ischemic hear... | left ventricular free wall rupture ( lvfwr ) is a serious complication of myocardial infarction .
it presents with a very high mortality rate and can be rescued by accurate diagnosis and emergency surgery .
lvfwr can occur with sudden overt clinical symptoms or present insidiously .
this report highlights the cas... |
ocular involvement is common in autoimmune disorders ; conversely , patients with autoimmune polyglandular syndrome ( aps ) frequently show vitiligo , alopecia , pernicious anemia , chronic hepatitis and uveitis1 , 2 . transgenic mice deficient for the autoimmune regulator gene develop type 1 aps and uveitis3 .
there... | abstractwe present a rare cause of iridocyclitis in a patient with vitiligo and type 1 diabetes who showed poor metabolic control , and suffered from remitting fever , weight loss , fatigue , diffuse arthralgias and reduced visual acuity .
mild systemic symptoms coupled with increased cholestasis enzymes , insulin re... |
plant root - released volatile and non - volatile chemicals transmit information to other plants or edaphon organisms ( badri and vivanco 2009 ; bais et al .
2006 ; rasmann et al . 2005 ; van tol et al . 2001 ; wenke et al . 2010 ) .
so far , technical limitations have rendered analyses of rhizosphere compound blen... | most studies on rhizosphere chemicals are carried out in substrate - free set - ups or in artificial substrates using sampling methods that require an air flow and may thus cause disturbance to the rhizosphere .
our study aimed to develop a simplified and inexpensive system that allows analysis of rhizosphere chemica... |
a living kidney donor can improve the quality of life and offer a survival advantage to the recipient .
since 1998 , as per organ procurement and transplantation network data , there have been approximately 309,319 kidney transplantations and of these approximately 108,150 are from living kidney donors .
the shorta... | evaluation of the potential kidney donor is a complex activity that differs substantially from other types of preoperative assessments .
the well being of the donor , who derives no medical benefit from this surgery , must be assured in both the short term and long term , and the potential adverse consequences to the... |
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