T19	Positive_regulation 48 57	modulated
E1	Positive_regulation:T19 Theme:T1 Cause:T2
T20	Activation 114 123	activated
E2	Activation:T20 Theme:T3
T21	Gene_expression 160 170	expressing
E3	Gene_expression:T21 Theme:T4
T22	Regulation 236 246	protection
E4	Regulation:T22 Theme:T5 Cause:T6
T23	Negative_regulation 408 416	prevents
E5	Negative_regulation:T23 Theme:E6
T24	Activation 422 432	activation
E6	Activation:T24 Theme:T8
T25	Negative_regulation 621 629	inhibits
E7	Negative_regulation:T25 Theme:T11 Cause:T9
T26	Positive_regulation 734 742	modulate
E8	Positive_regulation:T26 Theme:T13 Cause:T12
T27	Regulation 931 941	unaffected
E9	Regulation:T27 Theme:T16 Cause:T17
E10	Regulation:T27 Theme:T16 Cause:T18
M1	Negation E9
M2	Negation E10