P53-CSU1.csv

number,TP53 mut,TP53 mut location,TP53 mutation type (0-wild type; 1-nonsense mutation; 2-missense mutation),TP53 mutation types,TP53 mutation,TP53 exon,"TP53 exons: EX5: 0, EX6: 1, EX7: 2, EX8: 3, others: 4",TP53��,"EGFR mutation site, EX19 del, ins, t790m",EGFR mutation site,EGFR mutation status,EGFR exon,"��ǩEGFR������EX18, EX19:0,EX20:1;EX21:2,����",EGFR exon tag,Tumor mutation burden,TMB,TMB_low,TMB_high,KRAS variant sites,KRAS mutations,KRAS exon,BRAF mutation site,BRAF exon,C-met variant sites,C-met exon,ALK variant sites,ALK mutations,ALK exon,other()
1487260,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1490597,No,,,0,0,,,,,,,,,,,,,,,0,,,,,,ALK-EML4�ں�,1,EX19:EX13,
1488704,No,,,0,0,,,,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1487023,No,,,0,0,,,,,,,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,p.G12V,1,EX2,,,,,,0,,
1477715,Yes,c.743G>A:p.R248Q,2,2,1,EX7,2,2,,,,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,p.A59E,1,EX3,,,,,,0,,
1488262,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,5.76 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1487443,No,,,0,0,,,,p.V769_D770insASV,p.V769_D770insASV,1.0,EX20,1.0,1.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1486908,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1481223,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1476843,No,,,0,0,,,,,,,,,,2.88 Muts/Mb��TMB-L,0.0,0.0,,p.G13C,1,EX2,,,,,,0,,
1484963,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1487820,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,5.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1478236,Yes,"c.96+1G>T:.,p.D281Y, p.D281N",2,2,1,"IVS3,EX8",3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1485428,No,,,0,0,,,,,,,,,,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1487068,Yes,c.672+1G>T:.,1,1,1,IVS6,IVS6,4,,,0.0,,,,,,,,p.G13D,1,EX2,,,,,,0,,
1487518,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1485627,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1485486,Yes,c.731G>A:p.G244D,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1487773,Yes,c.638delG:p.R213Hfs*34,1,1,1,EX6,1,1,p.L747_T751delinsP,p.L747_T751delinsP,1.0,EX19,0.0,0.0,,0.0,0.0,,,0,,,,,,,0,,
1485472,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1483405,No,,,0,0,,,,,,0.0,,,,9.75 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1484187,No,,,0,0,,,,,,0.0,,,,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK,1,�ںϣ�V3��,
1485008,Yes,c.818G>A:p.R273H,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,4.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1485938,No,,,0,0,,,,,,0.0,,,,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1487877,Yes,c.818G>T:p.R273L,2,2,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,EGFR����
1487526,No,,,0,0,,,,p.E746del,p.E746del,1.0,EX19,0.0,0.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1486514,No,,,0,0,,,,,,0.0,,,,3.84 Muts/Mb��TMB-L,0.0,0.0,,,0,,p.L485_N486delinsY,EX12,,,,0,,
1486072,Yes,c.818G>A:p.R273H,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1486701,Yes,c.673-2A>G:.,1,1,1,IVS6,IVS6,4,,,0.0,,,,,,,,,0,,p.D594G,EX15,,,,0,,
1488879,Yes,c.118delA:p.M40Wfs*4,1,1,1,EX4,EX4,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,10.5 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,EGFR����
1478634,Yes,c.451C>T:p.P151S,2,2,1,EX5,0,0,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1482742,Yes,p.E2240D;c.832C>G:p.P278A,2,2,1,"EX6,EX8",1,1,,,0.0,,,,,,,,p.G12D,1,EX2,,,,,,0,,KRAS����
1486002,Yes,c.524G>A:p.R175H,2,2,1,EX7,2,2,,,0.0,,,,7.68Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1483429,Yes,c.515T>A:p.V172D,2,2,1,EX5,0,0,p.T751_I759delinsN,p.T751_I759delinsN,1.0,EX19,0.0,0.0,2.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1486199,Yes,c.818G>A:p.R273H,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1480602,No,,,0,0,,,,,,0.0,,,,1.5 Muts/Mb��TMB-L,0.0,0.0,,p.G12C,1,EX2,,,,,,0,,
1477611,Yes,c.747G>T:p.R249S,2,2,1,EX7,2,2,,,0.0,,,,18.0 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1481355,No,,,0,0,,,,,,0.0,,,,3.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1481715,No,,,0,0,,,,,,0.0,,,,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1478242,No,,,0,0,,,,,,0.0,,,,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1480453,No,,,0,0,,,,,,0.0,,,,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1477184,Yes,c.413C>T:p.A138V,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1458475,Yes,c.833C>G:p.P278R,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,4.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1482057,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,5.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1480235,Yes,c.293C>G:p.P98R;c.557delA:p.D186Vfs*61,1,1,1,EX4;EX5,EX4;0,4,,,1.0,,,,6.0Muts/Mb��TMB-L,0.0,0.0,,p.G12V;p.Q61R,1,EX2;EX3,,,,,,0,,
1480005,No,,,0,0,,,,p.A763_Y764insFQEA,p.A763_Y764insFQEA,1.0,EX20,1.0,1.0,2.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1479844,Yes,c.307dupT:p.Y103Lfs*46,1,1,1,EX4,EX4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1485465,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1485474,No,,,0,0,,,,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1483890,Yes,c.602delT:p.L201Cfs*46,1,1,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1482789,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1482296,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1483726,No,,,0,0,,,,p.A763_Y764insFQEA,p.A763_Y764insFQEA,1.0,IVS19,,,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1485684,Yes,c.812A>T:p.E271V,2,2,1,EX8,3,3,,,0.0,,,,6.0 Muts/Mb��TMB-L,0.0,0.0,,p.G12D,1,EX2,,,,,,0,,
1389532,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1486471,No,,,0,0,,,,,,0.0,,,,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1486472,Yes,����ϵ��: 1.4,0,0,0,,,,,,0.0,,,,,,,,p.G12A,1,EX2,,,,,,0,,KRAS����
1486821,Yes,c.702_703dupCA:p.N235Tfs*13,1,1,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1482713,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.75Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1484102,Yes,c.659A>G:p.Y220C,2,2,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1485780,No,,,0,0,,,,p.V769_D770insASV,p.V769_D770insASV,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1486337,Yes,c.497C>G:p.S166*,1,1,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1486186,No,,,0,0,,,,,,0.0,,,,0.96Muts/Mb��TMB-L,0.0,0.0,,p.G12D,1,EX2,,,,,,0,,
1483710,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1466962,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1477930,No,,,0,0,,,,,,0.0,,,,2.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ں�;ALK-BIN1,1,EX13:EX20;EX19:intergenic,
1485760,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ں�,1,EX13��EX20,
1480965,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1481883,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1482872,Yes,c.455delC:p.P152Rfs*18,1,1,1,EX5,0,0,p.L858R;p.V1010D,p.L858R;p.V1010D,1.0,EX21;EX25,2.0,2.0,,,,,,0,,,,,,,0,,
1480302,No,,,0,0,,,,,,0.0,,,,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1480040,No,,,0,0,,,,,,0.0,,,,11.25 Muts/Mb��TMB-H,1.0,,1.0,p.G13C,1,EX2,,,,,,0,,
1483448,No,,,0,0,,,,,,0.0,,,,8.25Muts/Mb��TMB-L,0.0,0.0,,p.G12V,1,EX2,,,,,,0,,
1438968,Yes,"c.747G>T:p.R249S
����ϵ��: 0.61",2,2,1,EX7,2,2,,,0.0,,,,9.75 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,EGFR����
1484479,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1482023,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1484140,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1479472,No,,,0,0,,,,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1483130,Yes,"
����ϵ��: 0.39",0,0,0,,,,p.E746_S752delinsV,p.E746_S752delinsV,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1483149,Yes,c.742C>T:p.R248W,2,2,1,EX7,2,2,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,4.8 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1483019,Yes,c.357_358delCAinsTT:p.K120*,1,1,1,EX4,EX4,4,,,0.0,,,,20.16 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1482403,No,,,0,0,,,,p.L858R;p.A289D,p.L858R;p.A289D,1.0,EX21;EX7,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1481287,No,,,0,0,,,,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1481108,No,,,0,0,,,,,,0.0,,,,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1481884,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.84 Muts/Mb��TMB-L,0.0,0.0,,,0,,BRAF-IRXZ�ں�,EX8��intergenic,,,,0,,
1482307,Yes,c.670G>T:p.E224*,1,1,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1484737,No,,,0,0,,,,,,0.0,,,,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ�V1��,1,EX13��EX20,
1479587,No,,,0,0,,,,,,0.0,,,,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1479272,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1478888,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1482767,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1483074,No,,,0,0,,,,,,0.0,,,,4.8 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1485062,Yes,c.720T>A:p.S240R,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1485466,Yes,c.817C>T:p.R273C,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1482425,Yes,c.945_946delTC:p.Q317Afs*19,1,1,1,EX9,EX9,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1482424,Yes,c.404G>A:p.C135Y,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1480252,Yes,c.466delC:p.R156Afs*14,1,1,1,EX5,0,0,,,0.0,,,,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1483127,Yes,c.994-1G>C:.,2,2,1,IVS9,IVS9,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1481030,Yes,c.736A>G:p.M246V,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1480334,Yes,c.574C>T:p.Q192*,1,1,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1477009,Yes,c.659A>G:p.Y220C,2,2,1,EX5,0,0,,,0.0,,,,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1483383,No,,,0,0,,,,,,0.0,,,,3.84 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1482520,Yes,c.469_471dupGTC:p.V157_R158insV,2,2,1,EX5,0,0,,,0.0,,,,5.76Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1479251,No,,,0,0,,,,p.H773delinsPNPY,p.H773delinsPNPY,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1482426,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1477740,No,,,0,0,,,,,,0.0,,,,3.84 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1478636,Yes,c.719G>T:p.S240I,2,2,1,EX7,2,2,,,0.0,,,,7.68Muts/Mb��TMB-L,0.0,0.0,,p.G12C,1,EX2,,,,,,0,,
1481285,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,6.72 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1482036,No,,,0,0,,,,p.L747_T751del;p.L838V,p.L747_T751del;p.L838V,1.0,EX19;EX21,0.0,0.0,,,,,,0,,,,,,,0,,
1480326,No,,,0,0,,,,,,0.0,,,,3.84 Muts/Mb��TMB-L,0.0,0.0,,p.G12C,1,EX2,,,,,,0,,
1478456,No,,,0,0,,,,p.K261E,p.K261E,1.0,EX7,,,,,,,,0,,,,,,,0,,
1473693,Yes,c.841G>C:p.D281H,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1473961,Yes,c.1073A>T:p.E358V;c.404G>A:p.C135Y,2,2,1,EX10;EX5,EX10;0,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1475613,Yes,c.476C>T:p.A159V,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1479876,No,,,0,0,,,,p.H773_V774delinsLM,p.H773_V774delinsLM,1.0,EX20,1.0,1.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1472842,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1475265,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1474854,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1482234,Yes,c.376-2A>T:.,2,2,1,IVS4,IVS4,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1479293,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1478872,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1476066,No,,,0,0,,,,,,0.0,,,,3.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ�V1��,1,EX13:EX20,
1476814,No,,,0,0,,,,p.L858R;p.V834L,p.L858R;p.V834L,1.0,EX21;EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1476780,Yes,c.653_660delTGCCCTAT:p.V218Gfs*4,1,1,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1473621,Yes,c.461G>T:p.G154V,2,2,1,EX5,0,0,,,0.0,,,,22.08 Muts/Mb��TMB-H,1.0,,1.0,p.G12D,1,EX2,,,,,,0,,
1476700,No,,,0,0,,,,,,0.0,,,,7.5Muts/Mb��TMB-L,0.0,0.0,,p.G12C,1,EX2,,,,,,0,,
1478239,Yes,"c.214_224delCCCGTGGCCCC:p.P72Cfs*73
����ϵ��: 0.64",1,1,1,EX4,EX4,4,,,0.0,,,,.0 Muts/Mb��TMB-H,0.0,0.0,,,0,,,,,,,0,,
1478157,Yes,c.772G>A:p.E258K,2,2,1,EX7,2,2,,,0.0,,,,7.68 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR ����
1479609,Yes,c.817C>T:p.R273C,2,2,1,EX8,3,3,,,0.0,,,,16.32 Muts/Mb��TMB-H,1.0,,1.0,,0,,p.G469R,EX11,,,,0,,
1479607,Yes,c.713G>A:p.C238Y,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,5.76 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1479289,Yes,c.724T>G:p.C242G,2,2,1,EX7,2,2,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1478137,Yes,c.994-1G>A:.,2,2,1,IVS9,IVS9,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,5.76 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,p.R1181C,1,EX23,EGFR����
1481036,Yes,c.919+1G>A:.,2,2,1,IVS8,IVS8,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1475285,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1481041,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,KRAS������EGFR����
1481423,Yes,c.783-2A>G:.,2,2,1,IVS7,IVS7,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1479353,Yes,c.736A>G:p.M246V,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1468835,No,,,0,0,,,,p.H835L;p.L833V,p.H835L;p.L833V,1.0,EX21;EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1453089,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1479527,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1481011,Yes,c.1029_1030delGC:p.E343Dfs*3,1,1,1,EX10,EX10,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1477852,No,,,0,0,,,,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1477556,Yes,c.396_397delGAinsTT:p.K132_M133delinsNL,2,2,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1477866,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1482238,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ںϣ�V3��,1,EX6:EX20,
1479954,Yes,c.527G>T:p.C176F,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR ����
1479531,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1470469,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1470993,Yes,c.581T>G:p.L194R,2,2,1,EX6,1,1,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1475306,No,,,0,0,,,,,,0.0,,,,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1475898,No,,,0,0,,,,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1479371,Yes,c.734G>A:p.G245D,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1477279,No,,,0,0,,,,p.L747_T751del;p.L833V,p.L747_T751del;p.L833V,1.0,EX19;EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1475278,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,p.D594G,EX15,,,,0,,
1474818,No,,,0,0,,,,p.L858R;p.E709K,p.L858R;p.E709K,1.0,EX21;EX18,2.0,2.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1479288,Yes,c.338T>G:p.F113C,2,2,1,EX4,EX4,4,,,0.0,,,,8.64Muts/Mb��TMB-,0.0,0.0,,p.A146T,1,EX4,,,,,,0,,
1480599,Yes,c.96+1G>A:.,1,1,1,IVS3,IVS3,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,6.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1474876,Yes,c.643A>G:p.S215G,2,2,1,EX6,1,1,,,0.0,,,,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1475670,Yes,c.1123C>T:p.Q375*,1,1,1,EX11,EX11,4,,,0.0,,,,1.5 Muts/Mb��TMB-L,0.0,0.0,,p.G12D,1,EX2,,,,,,0,,
1475334,No,,,0,0,,,,,,0.0,,,,0.96 Muts/Mb��TMB-L,0.0,0.0,,p.G12V,1,EX2,,,,,,0,,
1454023,Yes,c.376-1G>A:.,2,2,1,IVS4,IVS4,4,,,0.0,,,,11.25 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,EGFR����
1475236,No,,,0,0,,,,,,0.0,,,,6.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1478724,Yes,c.772G>A:p.E258K,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1477067,No,,,0,0,,,,,,0.0,,,,4.8 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1479406,Yes,"
SV: TP53-NTRK1; NTRK1-TP53",�����ں�,1,1,EX10:EX11;EX11:EX11,EX10:EX11;EX11:EX11,4,,,0.0,,,,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1477968,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1474230,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ںϣ�V3��,1,EX6:EX20,
1475863,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR ����
1478097,Yes,c.844C>T:p.R282W,2,2,1,EX8,3,3,p.L747_P753delinsS;p.D612H,p.L747_P753delinsS;p.D612H,1.0,EX19;EX15,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1475818,Yes,c.743G>A:p.R248Q,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.84 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1475619,No,,,0,0,,,,,,0.0,,,,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1479235,Yes,c.307_308dupTA:p.Q104Tfs*20,1,1,1,EX4,EX4,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1477636,Yes,c.1015G>T:p.E339*,1,1,1,EX10,EX10,4,,,0.0,,,,,,,,p.G12R,1,EX2,,,,,,0,,
1477334,No,,,0,0,,,,,,0.0,,,,11.52Muts/Mb��TMB-H,1.0,,1.0,p.G13D,1,EX2,p.R437L,EX10,,,,0,,
1478553,No,,,0,0,,,,,,0.0,,,,7.68 Muts/Mb��TMB-L,0.0,0.0,,p.G12A,1,EX2,,,,,,0,,
1477062,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1475849,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1477011,No,,,0,0,,,,,,0.0,,,,3.84 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,p.D1010Gfs*5,EX14,,0,,
1479330,Yes,c.782+2T>C:.,2,2,1,IVS7,IVS7,4,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,6.72 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1476821,Yes,c.1006G>T:p.E336*,1,1,1,EX10,EX10,4,p.L747_T751delinsP,p.L747_T751delinsP,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1476709,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1474447,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1473017,No,,,0,0,,,,,,0.0,,,,6.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1475474,Yes,c.592G>T:p.E198*,1,1,1,EX6,1,1,,,0.0,,,,,,,,,0,,p.T599del,EX15,,,,0,,
1471387,No,,,0,0,,,,,,0.0,,,,,,,,p.G12V,1,EX2,,,,,,0,,
1469200,No,,,0,0,,,,p.L861Q,p.L861Q,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1469825,No,,,0,0,,,,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1472240,Yes,c.994-1G>T:.,1,1,1,IVS9,IVS9,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1470292,Yes,c.413C>T:p.A138V,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1474359,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1478739,No,,,0,0,,,,EGFR-RADS1�ں�,EGFR-RADS1�ں�,1.0,EX25��EX4,,,,,,,,0,,,,,,,0,,
1474248,Yes,c.731G>A:p.G244D,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1473902,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1477630,Yes,c.832C>T:p.P278S,2,2,1,EX8,3,3,p.E746_T751delinsS;p.L62R,p.E746_T751delinsS;p.L62R,1.0,EX19;EX2,0.0,0.0,,,,,,0,,,,,,,0,,
1472234,Yes,c.743G>T:p.R248L,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1474213,Yes,c.848G>C:p.R283P,2,2,1,EX8,3,3,p.N771_P772insG,p.N771_P772insG,1.0,EX20,1.0,1.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1476655,Yes,c.757A>G:p.T253A,2,2,1,EX7,2,2,p.L747_T751del;p.T790M,p.L747_T751del;p.T790M,1.0,EX19;EX20,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1477051,Yes,c.313G>T:p.G105C,2,2,1,EX4,EX4,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1477272,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1477632,Yes,c.853G>A:p.E285K,2,2,1,EX8,3,3,,,0.0,,,,4.8 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1476137,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1474283,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,MET �ںϡ�MET c.2888-6_2910delTTTAAGATCTGGGCAGTGAATTAGTTCGC,EX13:EX14;IVS13-EX14,,0,,
1477015,Yes,c.536A>T:p.H179L,2,2,1,EX5,0,0,p.L858R;p.I706T,p.L858R;p.I706T,1.0,EX21;EX18,2.0,2.0,,,,,,0,,,,,,,0,,
1476990,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1463040,Yes,c.794dupT:p.R267Tfs*5,1,1,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,KRAS������MET����
1476684,Yes,c.821T>C:p.V274A,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR ����
1473570,Yes,c.723delC:p.C242Afs*5,1,1,1,EX7,2,2,p.E746_S752delinsV,p.E746_S752delinsV,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1456046,Yes,c.309C>G:p.Y103*,1,1,1,EX4,EX4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1477033,Yes,c.272G>A:p.W91*,1,1,1,EX4,EX4,4,,,0.0,,,,3.84 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1477243,Yes,c.565G>A:p.A189T;c.836G>A:p.G279E,2,2,1,EX6;EX8,1,1,p.L747_P753delinsS;p.T790M,p.L747_P753delinsS;p.T790M,1.0,EX19;EX20,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1465155,No,,,0,0,,,,p.E746_S752delins,p.E746_S752delins,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1469302,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ںϣ�V3��,1,EX6:EX20,
1469616,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,p.S990R,EX14,,0,,
1468653,Yes,c.733G>T:p.G245C,2,2,1,EX7,2,2,p.L858R;p.T790M,p.L858R;p.T790M,1.0,EX21;EX20,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1469613,Yes,c.217delG:p.V73Wfs*50;c.91G:p.V31I,1,1,1,EX4;EX3,EX4;EX3,4,p.R750C;p.M534V,p.R750C;p.M534V,1.0,EX17;EX12,,,,,,,,0,,p.S399C,EX10,,,,0,,
1468652,No,,,0,0,,,,p.V592I,p.V592I,1.0,EX15,,,,,,,p.G12V,1,EX2,,,,,,0,,
1469614,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1475268,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1474261,Yes,"c.529C>T:p.P177S
����ϵ��: 0.52",2,2,1,EX5,0,0,p.L858R;p.R108K,p.L858R;p.R108K,1.0,EX21;EX3,2.0,2.0,,0.0,0.0,,,0,,,,,,,0,,MET������TP53ȱʧ
1475274,No,,,0,0,,,,,,0.0,,,,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,p.D543A,EX5,EML4-ALK�ںϣ�V1��,1,EX13:EX20,
1470082,No,,,0,0,,,,,,0.0,,,,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,MET�ں�,EX13:EX14,,0,,
1468604,No,,,0,0,,,,p.T751_I759delinsN,p.T751_I759delinsN,1.0,EX19,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1474875,Yes,c.659A>G:p.Y220C,2,2,1,EX6,1,1,p.S768I,p.S768I,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,EGFR����
1453124,No,,,0,0,,,,,,0.0,,,,,,,,p.G12R,1,EX2,,,,,,0,,
1474855,Yes,c.920-1G>T:.,2,2,1,IVS8,IVS8,IVS8,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1476493,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1476207,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1473243,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,KRAS ����
1472998,No,,,0,0,,,,,,0.0,,,,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ�V1��;ALK-SMC5�ں�,1,EX13:EX20;EX19��EX18,
1475504,Yes,c.880G>T:p.E294*,1,1,1,EX8,3,3,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,5.76 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1458495,No,,,0,0,,,,,,0.0,,,,0.75Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1464927,No,,,0,0,,,,,,0.0,,,,5.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1465458,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1471475,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1463652,Yes,c.542_543delGC:p.R181Lfs*4,1,1,1,EX5,0,0,p.V769M;p.G719A,p.V769M;p.G719A,1.0,EX20;EX18,1.0,1.0,,,,,,0,,,,,,,0,,
1466911,Yes,c.767C>A:p.T256K,2,2,1,EX7,2,2,,,0.0,,,,9.0 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1471489,No,,,0,0,,,,p.L858R;p.I744M,p.L858R;p.I744M,1.0,EX21;EX19,2.0,2.0,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1465927,Yes,c.583A>T:p.I195F,2,2,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1466658,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,4.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1472703,Yes,c.650T>A:p.V217E,2,2,1,EX6,1,1,,,0.0,,,,,,,,,0,,p.V600E,EX15,,,,0,,
1473226,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1471230,Yes,c.154dupC:p.Q52Pfs*5,1,1,1,EX4,EX4,4,,,0.0,,,,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1469736,Yes,c.818G>T:p.R273L,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1474627,Yes,c.833C>A:p.P278H,2,2,1,EX8,3,3,p.G719A,p.G719A,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1475923,Yes,c.736A>G:p.M246V,2,2,1,EX7,2,2,,,0.0,,,,22.08 Muts/Mb��TMB-H,1.0,,1.0,p.G12V,1,EX2,,,,,,0,,
1471559,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1474262,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,MET����
1474308,Yes,c.731G>T:p.G244V,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1473336,Yes,c.461G>T:p.G154V,2,2,1,EX5,0,0,,,0.0,,,,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1474850,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ںϣ�V3��,1,EX6:EX20,
1473540,No,,,0,0,,,,p.L747_T751del;p.T725M,p.L747_T751del;p.T725M,1.0,EX19;EX18,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1472038,Yes,c.584T>C:p.I195T,2,2,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1473229,Yes,c.1162G>C:p.E388Q;c.B42A>G:p.D281G,2,2,1,EX11;EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1474784,Yes,c.856G>T:p.E286*,1,1,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1473911,No,,,0,0,,,,,,0.0,,,,5.76 Muts/Mb��TMB-L,0.0,0.0,,p.G12C,1,EX2,p.I554T,EX13,,,,0,,
1471492,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1472900,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,6.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1471076,Yes,c.329G>T:p.R110L,2,2,1,EX4,EX4,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1471093,Yes,c.818G>T:p.R273L,2,2,1,EX8,3,3,,,0.0,,,,12.48 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1471847,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1468602,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1465459,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1473130,No,,,0,0,,,,p.L858R;p.A289T,p.L858R;p.A289T,1.0,EX21;EX7,2.0,2.0,,,,,,0,,,,,,,0,,
1466983,Yes,c.844C>T:p.R282W,2,2,1,EX8,3,3,,,0.0,,,,6.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1469983,Yes,c.742C>T:p.R248W,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1470793,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,5.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1470369,No,,,0,0,,,,,,0.0,,,,,0.0,0.0,,,0,,,,,,,0,,
1469095,No,,,0,0,,,,,,0.0,,,,15.75 Muts/Mb��TMB-H,1.0,,1.0,p.G12C,1,EX2,,,,,,0,,
1472319,No,,,0,0,,,,p.G719A,p.G719A,1.0,EX18,,,,,,,,0,,,,,,,0,,
1469234,No,,,0,0,,,,,,0.0,,,,3.84 Muts/Mb��TMB-L,0.0,0.0,,p.G12V,1,EX2,,,,,,0,,
1471175,No,,,0,0,,,,,,0.0,,,,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1470371,Yes,c.678delC:p.S227Lfs*20,1,1,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1468280,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1469098,Yes,c.548C>G:p.S183*,1,1,1,EX5,0,0,,,0.0,,,,0.75 Muts/Mb��TMB-L,0.0,0.0,,p.G12D,1,EX2,,,,,,0,,
1471730,No,,,0,0,,,,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1472907,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ںϣ�V1��,1,EX13:EX20,
1472414,Yes,c.641A>G:p.H214R,2,2,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR������MET����
1470873,Yes,c.97-2A>G:.,1,1,1,IVS3,IVS3,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1470605,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1472731,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1468269,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ںϣ�V1��;ALK-EFR38�ں�,1,EX13:EX20;EX19:EX5,
1463968,No,,,0,0,,,,p.V774_C775insHV,p.V774_C775insHV,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1472624,Yes,c.672+1G>T:.;c.461G>T:p.G154V,2,2,1,IVS6;EX5,IVS6;0,4,,,0.0,,,,15.36 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,MET����
1450294,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1430025,Yes,c.583A>T:p.I195F,2,2,1,EX6,1,1,,,0.0,,,,12.48 Muts/Mb��TMB-H,1.0,,1.0,p.G12D,1,EX2,,,,,,0,,
1471741,Yes,c.686_687delGT:p.C229Yfs*10,1,1,1,EX7,2,2,,,0.0,,,,25.92 Muts/Mb��TMB-H,1.0,,1.0,p.G12V,1,EX2,,,,,,0,,
1472761,Yes,c.469G>T:p.V157F,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1470901,No,,,0,0,,,,,,0.0,,,,,,,,,0,,p.G469V,EX11,,,,0,,
1471105,Yes,c.824G>A:p.C275Y,2,2,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1465933,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1463006,Yes,c.686_687delGT:p.C229Yfs*10,1,1,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,5.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1463077,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,2.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1472027,Yes,c.991C>T:p.Q331*;c.528C>G:p.C176W,2,2,1,EX9;EX5,EX9;0,4,,,0.0,,,,11.52 Muts/Mb��TMB-H,1.0,,1.0,,0,,p.V600E,EX15,,,,0,,
1472029,Yes,c.376-2A>G:.,2,2,1,IVS4,IVS4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.84 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1470368,Yes,c.637C>T:p.R213*,1,1,1,EX6,1,1,p.V769_D770insASV,p.V769_D770insASV,1.0,EX20,1.0,1.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1468841,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1469832,No,,,0,0,,,,p.L858R;p.V834L,p.L858R;p.V834L,1.0,EX21;EX21,2.0,2.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1467948,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92Muts/Mb��TMB-,0.0,0.0,,,0,,,,,,,0,,
1466415,Yes,c.739A>G:p.N247D,2,2,1,EX7,2,2,,,0.0,,,,4.8 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1471774,No,,,0,0,,,,p.E709A;p.G719A,p.E709A;p.G719A,1.0,EX18;EX18,,,,,,,,0,,,,,,,0,,
1467923,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1469238,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,4.5Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1472012,Yes,c.783dupT:p.G262Wfs*2,1,1,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,MET ����
1471785,No,,,0,0,,,,p.E746_T751delinsL,p.E746_T751delinsL,1.0,EX19,0.0,0.0,3.84 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1469475,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1463667,No,,,0,0,,,,,,0.0,,,,,,,,p.G12V,1,EX2,,,,,,0,,
1472132,Yes,"c.723delC:p.C242Afs*5
����ϵ��: 0.67",1,1,1,EX7,2,2,,,0.0,,,,,,,,p.G12D,1,EX2,,,,,,0,,TP53 ȱʧ
1468268,No,,,0,0,,,,p.L858R;p.V834L,p.L858R;p.V834L,1.0,EX21;EX21,2.0,2.0,0.75Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1472017,No,,,0,0,,,,,,0.0,,,,5.76 Muts/Mb��TMB-L,0.0,0.0,,p.G12C,1,EX2,,,,,,0,,
1463229,Yes,c.716A>G:p.N239S,2,2,1,EX7,2,2,,,0.0,,,,14.25 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1464801,No,,,0,0,,,,p.K745_E746insIPVAIK,p.K745_E746insIPVAIK,1.0,EX19,0.0,0.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1464623,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1464638,No,,,0,0,,,,p.V769_D770insASV,p.V769_D770insASV,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1468541,No,,,0,0,,,,p.T302H,p.T302H,1.0,EX8,,,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1465408,Yes,c.737T>G:p.M246R,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1465972,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,ALK-CADM2�ں�,1,EX19:intergenic,
1466263,No,,,0,0,,,,,,0.0,,,,0.75Muts/Mb��TMB-L,0.0,0.0,,p.G13D,1,EX2,p.G469V,EX11,,,,0,,
1450834,Yes,c.731G>A:p.G244D,2,2,1,EX7,2,2,p.T302H,p.T302H,1.0,EX8,,,4.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1464687,Yes,c.743G>T:p.R248L,2,2,1,EX7,2,2,,,0.0,,,,12.75Muts/Mb��TMB-H,1.0,,1.0,p.G12C,1,EX2,,,,,,0,,
1467969,No,,,0,0,,,,p.L861Q:p.L747V,p.L861Q:p.L747V,1.0,EX21:EX19,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1468474,No,,,0,0,,,,p.T751_I759delinsS,p.T751_I759delinsS,1.0,EX19,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1462777,Yes,c.797G>T:p.G266V,2,2,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1465163,Yes,c.602_603insT:p.L201Ffs*8,1,1,1,EX6,1,1,,,0.0,,,,16.32 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1468790,No,,,0,0,,,,,,0.0,,,,15.36 Muts/Mb��TMB-H,1.0,,1.0,p.G12A,1,EX2,,,,,,0,,
1465141,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1468154,Yes,c.638G>T:p.R213L,2,2,1,EX6,1,1,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1468018,Yes,c.363_366delTGTG:p.V122Lfs*47,1,1,1,EX4,EX4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,4.8 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1467028,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,3.84 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1467218,No,,,0,0,,,,p.L858R: p.S768I,p.L858R: p.S768I,1.0,EX20:EX21,1.0,1.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1466637,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1467915,Yes,c.843C>G:p.D281E,2,2,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1465659,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,p.K117R,1,EX4,,,,,,0,,
1467970,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,p.G12D,1,EX2,,,,,,0,,
1470875,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1463803,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,11.52Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1465432,Yes,c.452C>G:p.P151R,2,2,1,EX5,0,0,p.L858R:p.D1014Y,p.L858R:p.D1014Y,1.0,EX21:EX25,2.0,2.0,,,,,,0,,,,,,p.G129V,1,EX1,
1470636,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,c.2888-4_2907delTAAGATCTGGGCAGTGAATTAGTTinsA,IVS13-EX14,,0,,
1465427,No,,,0,0,,,,p.L858R: p.L747_T751del,p.L858R: p.L747_T751del,1.0,EX21:EX19,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1460212,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1462825,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1462859,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1463061,No,,,0,0,,,,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1463088,Yes,c.673-2A>T:.,1,1,1,,,,,,0.0,,,,10.5 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,EGFR������MET����
1463445,Yes,c.476C>A:p.A159D,2,2,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.75Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1465111,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,ALK-EML4�ں�,1,EX19:EX20,
1466974,Yes,c.376-4_379delACAGTACT:.,2,2,1,IVS4-EX5,IVS4-0,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,MET����
1467904,No,,,0,0,,,,,,0.0,,,,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1457496,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1466617,No,,,0,0,,,,,,0.0,,,,6.72 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1464621,Yes,c.469G>T:p.V157F,2,2,1,EX5,0,0,,,0.0,,,,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1465067,Yes,c.856G>A:p.E286K,2,2,1,EX8,3,3,p.A755G:p.L747_P753delinsS,p.A755G:p.L747_P753delinsS,1.0,EX19:EX19,0.0,0.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1467692,No,,,0,0,,,,,,0.0,,,,,,,,p.Q61H,1,EX3,,,,IVS13,,0,,
1450440,Yes,c.844C>T:p.R282W,2,2,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,KRAS����
1465070,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1468263,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1458191,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1459519,Yes,c.487T>C:p.Y163H,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1467308,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1468296,Yes,c.644G>A:p.S215N,2,2,1,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,p.R1436H,1,EX29,
1467245,Yes,c.991C>T:p.Q331*,1,1,1,EX9,EX9,4,,,0.0,,,,,,,,,0,,p.V600E,EX15,,,,0,,
1463533,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1460033,No,,,0,0,,,,p.H773_V774insPH,p.H773_V774insPH,1.0,EX20,1.0,1.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1468019,Yes,c.817C>T:p.R273C,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR������RICTOR����
1465648,No,,,0,0,,,,,,0.0,,,,3.84 Muts/Mb��TMB-L,0.0,0.0,,p.G12C,1,EX2,,,,,,0,,
1466455,Yes,c.404G>T:p.C135F,2,2,1,EX5,0,0,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1466808,Yes,c.842A>G:p.D281G,2,2,1,EX8,3,3,,,0.0,,,,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1463034,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1467034,Yes,c.817C>T:p.R273C,2,2,1,EX8,3,3,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1463031,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1465484,Yes,c.871A>T:p.K291*,1,1,1,EX8,3,3,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,p.E119D,1,EX1,
1464631,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1422043,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1459015,Yes,c.769C>G:p.L257V,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1466454,Yes,c.733G>C:p.G245R,2,2,1,EX7,2,2,,,0.0,,,,4.8Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1465616,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1461889,Yes,c.560-2A>T:.,1,1,1,IVS5,IVS5,4,p.G719A:p.N771_P772insN,p.G719A:p.N771_P772insN,1.0,EX18:EX20,,,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1461898,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1463339,Yes,c.1006G>T:p.E336*,1,1,1,EX10,EX10,EX10,,,0.0,,,,10.5Muts/Mb��TMB-H,1.0,,1.0,p.G12S,1,EX2,,,,,,0,,"EGFR����,MET����"
1464121,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1423014,No,,,0,0,,,,p.G724S: p.V769_D770insM,p.G724S: p.V769_D770insM,1.0,EX18:EX20,,,2.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1463477,No,,,0,0,,,,,,0.0,,,,1.5Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1460203,Yes,c.775G>T:p.D259Y,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1460490,Yes,c.993+2delT:.,2,2,1,IVS9,IVS9,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1458155,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1464085,Yes,c.833C>T:p.P278L,2,2,1,EX8,3,3,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,p.R510W:p.L1404V,1,EX7:EX29,
1461196,Yes,c.320_338delACGGTTTCCGTCTGGGCTTinsG:p.Y107_F113delinsC;p.G150P,2,2,1,EX4:EX4,EX4:EX4,4,,,0.0,,,,,,,,p.G12V,1,EX2,,,,,,0,,
1461930,No,,,0,0,,,,p.E709A: p.G719S,p.E709A: p.G719S,1.0,EX18:EX18,,,1.5Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1465560,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1464831,Yes,c.968delT:p.L323Rfs*22,1,1,1,EX9,EX9,4, p.L858R: p.T790M, p.L858R: p.T790M,1.0,EX21:EX20,2.0,2.0,,,,,p.D33E,1,EX2,,,,,,0,,
1462044,No,,,0,0,,,,p.Q61H,p.Q61H,1.0,EX3,,,6.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1458244,Yes,c.520A>T:p.R174W,2,2,1,EX5,0,0,,,0.0,,,,31.5Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1461858,No,,,0,0,,,,,,0.0,,,,1.5Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1464747,Yes,c.991C>T:p.Q331*,1,1,1,EX9,EX9,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,7.5Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1460465,No,,,0,0,,,,p.E746_A750del: p.R836C,p.E746_A750del: p.R836C,1.0,EX19:EX21,0.0,0.0,,,,,,0,,,,,,p.C1365R,1,EX28,
1464827,Yes,c.290_300delTCCCTTCCCAG:p.V97Efs*48,1,1,1,EX4,EX4,4,,,0.0,,,,,,,,,0,,p.V600E,EX15,,,,0,IVS3,EGFR������MET����
1464829,Yes,c.644G>A:p.S215N,2,2,1,EX6,1,1,p.E746_A750del:p.V948F,p.E746_A750del:p.V948F,1.0,EX19:EX23,0.0,0.0,,,,,,0,,,,,IVS13,,0,,EGFR������MET����
1461711,Yes,"
����ϵ��: 0.67",,0,0,,,,,,0.0,,,,,,,,p.G12D,1,EX2,,,,,,0,,KRAS������EGFR������CDK6������MET������CCND1������ERBB2������TP53ȱʧ
1462382,No,,,0,0,,,,p.L858R,p.L858R,1.0,,,,6.429Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1461220,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,EGFR����
1460668,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1461431,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1460760,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1463860,Yes,c.329G>T:p.R110L,2,2,1,EX4,EX4,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1461399,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,5.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1461853,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,4.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1460181,Yes,c.730G>A:p.G244S,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1460796,No,,,0,0,,,,p.E746_T751delinsI,p.E746_T751delinsI,1.0,EX19,0.0,0.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1460714,No,,,0,0,,,,,,0.0,,,,5.25 Muts/Mb��TMB-L,0.0,0.0,,p.G12C,1,EX2,,,,,,0,,
1462407,Yes,c.584T>C:p.I195T,2,2,1,EX6,1,1,p.D770_N771insSVD��TP53 p.I195T,p.D770_N771insSVD��TP53 p.I195T,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,EGFR����
1457166,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,7.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,NRAS����
1460489,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1343029,No,,,0,0,,,,,,0.0,,,,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1460038,No,,,0,0,,,,p.L861Q,p.L861Q,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1420027,No,,,0,0,,,,,,0.0,,,,4.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,p.G87V,EX2,,0,,
1462821,Yes,c.503A>G:p.H168R,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1279137,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1460525,Yes,c.766A>C:p.T256P,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1456161,Yes,c.536A>G:p.H179R,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1459713,Yes,c.692_694delCCA:p.T231del,2,2,1,EX7,2,2,,,0.0,,,,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,p.P666H,1,EX11,
1455569,No,,,0,0,,,,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1457516,No,,,0,0,,,,,,0.0,,,,6.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1456934,Yes,c.796G>T:p.G266*,1,1,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1460169,No,,,0,0,,,,p.L747_E749del:p.S720P,p.L747_E749del:p.S720P,1.0,EX19:EX18,0.0,0.0,9.0 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,EML4-ALK�ںϣ�V3��,1,,MET ����KRAS����
1461517,Yes,c.1010G>C:p.R337P,2,2,1,EX10,EX10,4,,,0.0,,,,12.0 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1460916,Yes,c.659A>C:p.Y220S,2,2,1,EX6,1,1, p.E746_A750del, p.E746_A750del,1.0,EX19,0.0,0.0,6.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1461221,Yes,c.376T>G:p.Y126D,2,2,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1461909,Yes,c.329G>T:p.R110L,2,2,1,EX4,EX4,4,,,0.0,,,,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1458207,Yes,c.973G>T:p.G325*; p.G266V,2,2,1,EX9:EX8,EX9:3,4,,,0.0,,,,16.5 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,EGFR����
1459522,No,,,0,0,,,,,,0.0,,,,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ں�(V3),1,,
1452148,No,,,0,0,,,,,,0.0,,,,6.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1457174,No,,,0,0,,,,p.L858R: p.T790M,p.L858R: p.T790M,1.0,EX21:EX20,2.0,2.0,,,,,,0,,,,,,,0,,
1457666,Yes,c.560-7_560delCTCTTAGG:.,1,1,1,IVS5-EX6,IVS5-1,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1449410,Yes,c.577C>T:p.H193Y,2,2,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1455853,Yes,c.637C>T:p.R213*,1,1,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1448688,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,7.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,KRAS����
1457845,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1455236,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1456473,Yes,c.358A>T:p.K120*,1,1,1,EX4,EX4,4,,,0.0,,,,35.25 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1455749,No,,,0,0,,,,p.L858R: p.T790M,p.L858R: p.T790M,1.0,EX21:EX20,2.0,2.0,,,,,,0,,,p.M484V,EX12,,,0,,
1458272,No,,,0,0,,,,p.5895R,p.5895R,1.0,EX22,,,,,,,,0,,,p.D22N,EX1,,,0,,EGFR����
1457054,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.5Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1454868,No,,,0,0,,,,,,0.0,,,,6.75 Muts/Mb��TMB-L,0.0,0.0,,p.G12F,1,EX2,,,,,,0,,
1458489,No,,,0,0,,,,p.L858R:p.T790M,p.L858R:p.T790M,1.0,EX21:EX20,2.0,2.0,,,,,,0,,,,,,p.51103P,1,EX20,
1453760,No,,,0,0,,,,,,0.0,,,,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1457260,Yes,c.375+1G>T:.,2,2,1,IVS4,IVS4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1457278,Yes,c.638G>T:p.R213L,2,2,1,EX6,1,1,,,0.0,,,,,,,,,0,,,,,,,0,,
1457811,No,,,0,0,,,,p.G719S: p.E709V,p.G719S: p.E709V,1.0,EX18:EX18,,,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1458687,No,,,0,0,,,,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1414474,Yes,c.742C>T:p.R248W,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1446525,Yes,c.659A>G:p.Y220C,2,2,1,EX6,1,1,p.R748S,p.R748S,1.0,EX19,0.0,0.0,,,,,p.G12C,1,EX2,,,,,,0,,
1450561,No,,,0,0,,,,,,0.0,,,,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1457778,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1458378,Yes,c.587G>C:p.R196P,2,2,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1458172,Yes,c.578A>G:p.H193R,2,2,1,EX6,1,1,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1456672,Yes,c.375+1G>T:.,2,2,1,IVS4,IVS4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1459152,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1459601,Yes,c.1024delC:p.R342Efs*3,1,1,1,EX10,EX10,4,,,0.0,,,,,,,,,0,,p.V600E,EX15,,,p.M1302V,1,EX26,
1459839,Yes,c.417G>T:p.K139N,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR ����
1459513,Yes,c.672+1G>T:.,1,1,1,IVS6,IVS6,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1437156,Yes,c.617_618insT:p.L206Ffs*3,1,1,1,EX6,1,1,,,0.0,,,,63.0Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1457167,Yes,c.493C>T:p.Q165*,1,1,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1458254,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1460802,Yes,c.298C>T:p.Q100*,1,1,1,EX4,EX4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR ����
1457295,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1430851,Yes,c.75-1G>C:.p.E271Q:0,2,2,1,EX8:IVS2,3,3,,,0.0,,,,15.75Muts/Mb��TMB-H,1.0,,1.0,p.G12C,1,EX2,,,,,,0,,
1460002,Yes,c.512A>G:p.E171G,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR ����
1449052,Yes,c.818G>A:p.R273H,2,2,1,EX8,3,3,p.G719A,p.G719A,1.0,EX18,,,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1456849,Yes,c.530C>G:p.P177R,2,2,1,EX5,0,0,,,0.0,,,,,,,,p.G12A,1,EX2,,,,,,0,,
1454094,Yes,c.763A>T:p.I255F,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1455945,Yes,c.490A>T:p.K164*,1,1,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,4.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,p.D594H,EX15,,,,0,,
1457769,No,,,0,0,,,,,,0.0,,,,12.75 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,p.R805G,1,EX14,
1455330,Yes,c.508dupA:p.T170Nfs*11,1,1,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1454561,Yes,c.743_759delGGAGGCCCATCCTCACC:p.R248Hfs*10,1,1,1,EX7,2,2,,,0.0,,,,,0.0,0.0,,,0,,p.P402H,EX10,,,,0,,
1455488,No,,,0,0,,,,,,0.0,,,,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1456551,No,,,0,0,,,,,,0.0,,,,3.75 Muts/Mb��TMB-L,0.0,0.0,,p.G12D,1,EX2,,,,,,0,,
1454054,Yes,c.404G>A:p.C135Y,2,2,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,5X19,,,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1454542,Yes,c.710T>A:p.M237K,2,2,1,EX7,2,2,,,0.0,,,,9.75 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1454764,No,,,0,0,,,,,,0.0,,,,,,,,p.G12D: p.G12R,1,EX2:EX2,,,,,,0,,
1455471,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1459016,No,,,0,0,,,,p.V769_D770insASV,p.V769_D770insASV,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1455341,Yes,c.461G>T:p.G154V,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1453088,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,p.L1196R,1,EX11,
1453112,Yes,c.527G>A:p.C176Y,2,2,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1455815,Yes,c.560-1_560delGGinsAT:.,1,1,1,IVS5-ES6,IVS5-ES6,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1457872,Yes,c.818G>A:p.R273H,2,2,1,EX8,3,3,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1456479,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1455652,Yes,c.216_217insC:p.V73Rfs*76,1,1,1,EX4,EX4,4,p.L858R:p.T790M,p.L858R:p.T790M,1.0,EX21:EX20,2.0,2.0,6.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1457449,Yes,c.335delG:p.G112Afs*11,1,1,1,EX4,EX4,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1448288,Yes,c.776A>T:p.D259V,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1454707,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1455252,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1455143,No,,,0,0,,,,,,0.0,,,,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,p.D1203N,1,EX23,
1454891,Yes,c.145_178delGATATTGAACAATGGTTCACTGAAGACCCAGGTC:p.D49Qfs*63,1,1,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,4.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1455470,Yes,c.785G>T:p.G262V,2,2,1,EX7,2,2,,,0.0,,,,9.75 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1458219,Yes,c.746G>T:p.R249M,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1456305,Yes,c.818G>T:p.R273L,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,p.L1404V,1,EX29,EGFR����
1455570,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1454638,Yes,c.538G>A:p.E180K,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,5X21,,,,,,,,0,,,,,,,0,,EGFR����
1457204,Yes,c.824G>T:p.C275F,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1454614,Yes,c.993+1G>T:.,1,1,1,IVS9,IVS9,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1456497,No,,,0,0,,,,p.A955T,p.A955T,1.0,EX24,,,,,,,,0,,,,,,,0,,
1454802,Yes,c.817C>T:p.R273C,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,5.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1456801,Yes,c.848G>C:p.R283P,2,2,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1449133,No,,,0,0,,,,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1449457,Yes,c.559+1G>A:.,2,2,1,IVS5,IVS5,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1452211,Yes,c.527G>T:p.C176F,2,2,1,EX5,0,0,,,0.0,,,,9.0 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1451067,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,5.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1451925,Yes,c.838A>G:p.R280G,2,2,1,EX8,3,3,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,6.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1455268,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,2.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1456199,Yes,c.821T>C:p.V274A,2,2,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1455933,Yes,c.375+2T>A:.,1,1,1,IVS5,IVS5,4,p.L861Q,p.L861Q,1.0,EX21,2.0,2.0,4.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1454632,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,6.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1455465,No,,,0,0,,,,p.D770_N771insSVD,p.D770_N771insSVD,1.0,EX20,1.0,1.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,p.T1563pfs*3,1,EX29 ,
1451892,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1455654,Yes,c.637C>T:p.R213*,1,1,1,EX6,1,1,,,0.0,,,,5.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1458318,Yes,c.200delC:p.P67Qfs*56,1,1,1,EX4,EX4,4,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,6.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1453447,No,,,0,0,,,,p.D770_N771insSVD,p.D770_N771insSVD,1.0,EX20,1.0,1.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1456465,Yes,c.377A>G:p.Y126C,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,MET����
1452640,No,,,0,0,,,,,,0.0,,,,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ�V1��,1,EX13��EX20,
1455616,Yes,c.839G>A:p.R280K,2,2,1,EX8,3,3,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1448560,Yes,c.472C>G:p.R158G,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1453748,Yes,c.844C>T:p.R282W,2,2,1,EX8,3,3,,,0.0,,,,42.0 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1428166,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,p.A1363T,EX21,,0,,
1448613,No,,,0,0,,,,p.E746_A750del:p.R255Q,p.E746_A750del:p.R255Q,1.0,EX19:EX7,0.0,0.0,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1451348,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1451816,Yes,c.326T>A:p.F109Y,2,2,1,EX4,EX4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1451032,Yes,c.376-2A>T:.,2,2,1,IVS4,IVS4,4,p.E746_T751delinsA,p.E746_T751delinsA,1.0,,,,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1453258,No,,,0,0,,,,,,0.0,,,,5.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1451809,No,,,0,0,,,,p.G719S:p.S768I,p.G719S:p.S768I,1.0,EX18:EX20,,,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1453110,No,,,0,0,,,,,,0.0,,,,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1449007,Yes,c.638G>T:p.R213L,2,2,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1451897,Yes,c.722C>T:p.S241F,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1436113,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1436382,Yes,c.747G>T:p.R249S,2,2,1,EX7,2,2,p.L833V,p.L833V,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1439416,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1447288,No,,,0,0,,,,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,9.0 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1449319,Yes,c.734G>A:p.G245D,2,2,1,EX7,2,2,,,0.0,,,,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ�V1��,1,EX13:EX20,
1431468,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1451000,Yes,c.991C>T:p.Q331*,1,1,1,EX9,EX9,4,,,0.0,,,,8.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1451342,No,,,0,0,,,,,,0.0,,,,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1453054,No,,,0,0,,,,p.E709_T710delinsD,p.E709_T710delinsD,1.0,EX18,,,,0.0,0.0,,,0,,,,,,,0,,
1453720,No,,,0,0,,,,,,0.0,,,,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1450559,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1450506,Yes,c.740A>T:p.N247I,2,2,1,EX7,2,2,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,10.5 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1451328,No,,,0,0,,,,p.E746_T751delinsA,p.E746_T751delinsA,1.0,EX19,0.0,0.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1449677,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1446390,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1449174,No,,,0,0,,,,,,0.0,,,,1.5 Muts/Mb��TMB-L,0.0,0.0,,p.G12D,1,EX2,,,,,,0,,
1450292,No,,,0,0,,,,,,0.0,,,,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1451355,No,,,0,0,,,,p.L861Q,p.L861Q,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1449604,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1453943,Yes,c.614A>G:p.Y205C,2,2,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR������MET����
1453129,No,,,0,0,,,,,,0.0,,,,4.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ں�(��V1/V3),1,EX14:EX20,
1453705,Yes,c.830G>T:p.C277F,2,2,1,EX8,3,3, p.L858R, p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1446459,Yes,c.559+1G>T:.,1,1,1,IVS5,IVS5,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.00 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1448144,No,,,0,0,,,,,,0.0,,,,5.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1451012,No,,,0,0,,,, p.L747_T751del, p.L747_T751del,1.0,EX19,0.0,0.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1451658,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1449887,Yes,c.246_253delGGCGGCCC:p.A83Cfs*63,1,1,1,EX4,EX4,4,,,0.0,,,,4.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1447017,No,,,0,0,,,,,,0.0,,,,8.25 Muts/Mb��TMB-L,0.0,0.0,,p.G12V,1,EX2,,,,,,0,,
1446346,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.75Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1447013,No,,,0,0,,,,p.L858R��PIK3CA p.M1043I,p.L858R��PIK3CA p.M1043I,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1450185,Yes,c.535C>T:p.H179Y,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1451318,Yes,c.797G>A:p.G266E,2,2,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1449674,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1451472,Yes,c.1013delT:p.F338Sfs*7,1,1,1,EX10,EX10,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1448478,No,,,0,0,,,,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1450389,Yes,c.919+1G>T:.,1,1,1,IVS8,IVS8,4,,,0.0,,,,11.25 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1449802,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1446012,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1434028,Yes,c.711G>T:p.M237I,2,2,1,EX7,2,2,,,0.0,,,,24.96 Muts/Mb��TMB-H,1.0,,1.0,p.G12D,1,EX2,,,,,,0,,
1435458,Yes,c.713G>T:p.C238F,2,2,1,EX7,2,2,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1449971,No,,,0,0,,,,,,0.0,,,,,,,,,0,,p.G469R,EX11,,,,0,,
1450584,Yes,c.424_425delCCinsTT:p.P142F,2,2,1,EX5,0,0,,,0.0,,,,17.25 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1451599,Yes,c.744delG:p.R249Gfs*96,1,1,1,EX10,EX10,4,,,0.0,,,,28.5 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1310354,Yes,c.451C>T:p.P151S,2,2,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.75Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1446428,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1451335,No,,,0,0,,,,,,0.0,,,,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1451020,Yes,c.528_532delCCCCC:p.C176*fs*1,1,1,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1449927,Yes,c.604_618dupCGTGTGGAGTATTTG:p.L206_D207insRVEYL,2,2,1,EX6,1,1,p.E746_T751delinsA,p.E746_T751delinsA,1.0,EX19,0.0,0.0,6.75Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1435811,Yes,c.797G>A:p.G266E,2,2,1,EX8,3,3,,,0.0,,,,13.5 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,EGFR����
1449618,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1449249,No,,,0,0,,,,,,0.0,,,,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ�V1,1,EX13:EX20,
1449053,No,,,0,0,,,,,,0.0,,,,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,MTA3-ALK�ں�,1,EX8:EX20,
1450316,Yes,c.380C>T:p.S127F,2,2,1,EX5,0,0,,,0.0,,,,9.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1445485,Yes,c.919+2T>A:.,1,1,1,IVS8,IVS8,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1446076,Yes,c.517G>T:p.V173L,2,2,1,EX5,0,0,,,0.0,,,,15.75 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1443782,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1381205,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1450721,Yes,c.833C>G:p.P278R,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,4.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1446921,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1447052,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1449454,Yes,c.919_919+1delGGinsTT:.,1,1,1,"EX8,IVS8","3,IVS8",3,,,0.0,,,,9.75 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1446848,No,,,0,0,,,,,,0.0,,,,10.5 Muts/Mb��TMB-H,1.0,,1.0,p.G12C,1,EX2,,,,,,0,,
1447654,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1450875,Yes,c.581T>G:p.L194R,2,2,1,EX6,1,1,"p.L858R,p.T790M","p.L858R,p.T790M",1.0,"EX21,EX20",2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1445509,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,9.75 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1448067,No,,,0,0,,,,p.E746_S752delinsV,p.E746_S752delinsV,1.0,EX19,0.0,0.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1447859,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1446311,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1446053,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1448269,Yes,c.559+1G>T:.,2,2,1,IVS5,IVS5,4,p.E746_A750de,p.E746_A750de,1.0,EX19,0.0,0.0,2.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1444304,Yes,c.642delT:p.H214Qfs*33,1,1,1,EX6,1,1,p.G719A,p.G719A,1.0,EX18,,,,0.0,0.0,,,0,,,,,,,0,,EGFR����
1445577,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1448650,Yes,c.743G>A:p.R248Q,2,2,1,EX7,2,2,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,0.75Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1449812,Yes,c.159G>A:p.W53*,1,1,1,EX4,EX4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,0.0,0.0,,,0,,,,,,,0,,EGFR����
1443422,Yes,c.757dupA:p.T253Nfs*11,1,1,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,6.75Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1446992,No,,,0,0,,,,p.P772_H773insDNP,p.P772_H773insDNP,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1448038,No,,,0,0,,,,,,0.0,,,,3.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ���V1/V3��,1,EX20:EX20,
1448201,Yes,c.837delG:p.R280Efs*65,1,1,1,EX8,3,3,,,0.0,,,,8.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1444380,Yes,c.827C>G:p.A276G,2,2,1,EX8,3,3,p.L747P,p.L747P,1.0,EX19,0.0,0.0,3.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1448011,Yes,c.1013_1015delTCG:p.F338*,1,1,1,EX10,EX10,4,p.L861Q,p.L861Q,1.0,EX21,2.0,2.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1448017,Yes,c.659A>G:p.Y220C,2,2,1,EX6,1,1,,,0.0,,,,,,,,,0,,,,,,,0,,
1446211,No,,,0,0,,,,,,0.0,,,,3.75Muts/Mb��TMB-L,0.0,0.0,,,0,,,,c.2888-21_2891delTTTCTTTCTCTCTGTTTTAAGATCT,IVS13-EX14,,0,,
1446692,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1446631,Yes,c.1011delC:p.F338Sfs*7,1,1,1,EX7,2,2,p.V769_D770insASV,p.V769_D770insASV,1.0,EX20,1.0,1.0,3.75Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1448439,Yes,"
����ϵ��: 1.5812, 1.4187, 1.4174",2,2,1,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,2.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1445808,No,,,0,0,,,,p.E746_T751delinsVP,p.E746_T751delinsVP,1.0,EX19,0.0,0.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1439907,Yes,c.884C>T:p.P295L,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1444863,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1444822,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1444883,Yes,c.560-2A>C:.,1,1,1,IVS5,IVS5,4,p.E746_T751delinsA,p.E746_T751delinsA,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1445799,Yes,c.610G>T:p.E204*,1,1,1,EX6,1,1,,,0.0,,,,6.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1445626,No,,,0,0,,,,,,0.0,,,,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1441083,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1441964,Yes,c.892G>T:p.E298*,1,1,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1442867,Yes,c.273G>A:p.W91*,1,1,1,EX4,EX4,4,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1443705,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1446009,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1429290,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1424982,Yes,c.351_352dupGA:p.T118Rfs*6,1,1,1,EX4,EX4,4,,,1.0,,,,,,,,,0,,,,,,,0,,
1393292,Yes,c.423C>A:p.C141*,1,1,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1442624,No,,,0,0,,,,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1437468,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,5.76 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1445511,No,,,0,0,,,,c.2284-6_2284-5insTCCAGGAAGCCT,c.2284-6_2284-5insTCCAGGAAGCCT,1.0,IVS19,,,2.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1444990,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,2.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1445359,No,,,0,0,,,,p.D770_N771insSVD,p.D770_N771insSVD,1.0,EX20,1.0,1.0,2.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1443195,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.75Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1445015,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1443475,No,,,0,0,,,,,,0.0,,,,0.75Muts/Mb��TMB-L,0.0,0.0,,p.G12A,1,EX2,,,,,,0,,
1446760,No,,,0,0,,,,p.E746_A750delinsIP,p.E746_A750delinsIP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1445693,Yes,c.351delG:p.T118Qfs*5,1,1,1,EX4,EX4,4,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ���V1/V3��,1,EX13:EX19,
1446698,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1444788,No,,,0,0,,,,"p.L861Q,p.G719A","p.L861Q,p.G719A",1.0,EX21:EX18,2.0,2.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1438299,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1443022,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1440121,Yes,c.723delC:p.C242Afs*5,1,1,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1444174,Yes,c.461delG:p.G154Afs*16,1,1,1,EX5,0,0,,,0.0,,,,18.0 Muts/Mb��TMB-H,1.0,,1.0,,0,,,IVS1,,,,0,,
1444675,Yes,c.560-1G>A:.,1,1,1,IVS5,IVS5,4,,,0.0,,,,8.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1444090,Yes,c.814G>A:p.V272M,2,2,1,EX8,3,3,,,0.0,,,,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ�V1��,1,EX13:EX20,
1441087,Yes,c.839G>A:p.R280K,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1437474,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1437296,Yes,c.955A>T:p.K319*,1,1,1,EX9,EX9,4,,,0.0,,,,3.84 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1440446,No,,,0,0,,,,"p.G719S,p.S768I","p.G719S,p.S768I",1.0,"EX18,EX20",,,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1441887,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1443034,No,,,0,0,,,,p.L861Q,p.L861Q,1.0,EX21,2.0,2.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1440274,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1442452,Yes,c.731G>T:p.G244V,2,2,1,EX7,2,2,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,4.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1439039,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1440042,No,,,0,0,,,,,,0.0,,,,5.25Muts/Mb��TMB-L,0.0,0.0,,p.G12C,1,EX2,,,,,,0,,
1439118,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1437668,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1442874,No,,,0,0,,,,,,0.0,,,,3.0 Muts/Mb��TMB-L,0.0,0.0,,p.G12D,1,EX2,,,,,,0,,
1443989,Yes,c.527G>T:p.C176F,2,2,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1443788,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1444231,Yes,c.96+1G>T:.,2,2,1,IVS3,IVS3,4,,,0.0,,,,12.0 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1443192,Yes,c.818G>T:p.R273L,2,2,1,EX6,1,1,,,0.0,,,,12.0 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1444646,No,,,0,0,,,,,,0.0,,,,12.75 Muts/Mb��TMB-H,1.0,,1.0,"p.G12D,p.G12A",1,EX2,,,,,,0,,
1438726,Yes,c.817C>A:p.R273S,2,2,1,EX8,3,3,p.E746_T751delinsA,p.E746_T751delinsA,1.0,EX19,0.0,0.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1438108,Yes,c.866_867delTC:p.L289Pfs*16,1,1,1,EX8,3,3,p.L747_P753delinsQ,p.L747_P753delinsQ,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1439190,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1444955,Yes,c.469G>T:p.V157F,2,2,1,EX5,0,0,,,0.0,,,,9.75Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1440622,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1440485,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.75 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1436122,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1438862,No,,,0,0,,,,p.L747_S752delinsQL,p.L747_S752delinsQL,1.0,EX19,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1440168,No,,,0,0,,,,p.L858R��p.T790M,p.L858R��p.T790M,1.0,"EX21,EX20",2.0,2.0,,,,,,0,,,,,,,0,,
1441736,Yes,c.880G>T:p.E294*,1,1,1,EX8,3,3,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1441899,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1440433,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.75Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1440729,Yes,c.580C>T:p.L194F,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.25 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1443367,Yes,c.452C>A:p.P151H,2,2,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,5.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1436120,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ں�(V3),1,EX6:EX20,
1437427,Yes,c.1015G>T:p.E339*,1,1,1,EX10,EX10,4,,,0.0,,,,,,,,p.G12A,1,EX2,,,,,,0,,
1439469,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1436985,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1435618,No,,,0,0,,,,p.L747_S752del,p.L747_S752del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1436114,Yes,c.626_627delGA:p.R209Kfs*6,1,1,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1442116,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1441555,Yes,c.949delC:p.Q317Sfs*28,1,1,1,EX9,EX9,4,"p.L858R, p.L747_T751del","p.L858R, p.L747_T751del",1.0,"EX21,EX19",2.0,2.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1439812,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.5 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1441141,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1442469,Yes,c.733G>A:p.G245S,2,2,1,EX7,2,2,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,KRAS������MET����
1442356,Yes,c.538G>A:p.E180K,2,2,1,EX5,0,0,,,0.0,,,,5.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ�V1��,1,EX13:EX20,
1440111,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1445250,Yes,c.314G>T:p.G105V,2,2,1,EX4,EX4,4,p.E746_A750delinsIP,p.E746_A750delinsIP,1.0,EX19,0.0,0.0,2.25Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1441282,Yes,c.742C>T:p.R248W,2,2,1,EX7,2,2,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,,,,,,0,,,,,,p.A541V,1,EX8,
1442997,No,,,0,0,,,,,,0.0,,,,,,,,p.G12D,1,EX2,,,,,,0,,
1433487,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,p.N338S,EX2,,0,,
1439717,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,p.Q61H,1,EX3,,,,,,0,,
1439271,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1439483,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1439662,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,NKAIN2��intergenic��-ALK�ں�,1,intergenic:EX20,
1439656,No,,,0,0,,,,,,0.0,,,,,,,,p.G12V,1,EX2,,,,,,0,,
1441114,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1438193,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1438060,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1439799,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,p.G12D,1,EX2,,,,,,0,,
1439778,Yes,c.839G>T:p.R280I,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,5.76 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1367868,Yes,c.386C>A:p.A129D,2,2,1,EX5,0,0,p.T751_I759delinsN,p.T751_I759delinsN,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1438470,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1439657,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1437011,Yes,c.569delC:p.P190Lfs*57,1,1,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1437076,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1437263,Yes,c.993G>C:p.Q331H,2,2,1,EX9,EX9,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1438168,No,,,0,0,,,,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1437441,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1437081,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1438074,No,,,0,0,,,,p.L747P,p.L747P,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1433352,Yes,c.836G>A:p.G279E,2,2,1,EX8,3,3,"p.E709A, p.L858R","p.E709A, p.L858R",1.0,"EX18,EX21",,,,,,,,0,,,,,,,0,,
1412690,Yes,c.634T>G:p.F212V,2,2,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1440112,Yes,c.130delA:p.M44Cfs*79,1,1,1,EX4,EX4,4,p.E746_S752delinsV,p.E746_S752delinsV,1.0,EX19,0.0,0.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1438068,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1439472,Yes,c.920-2A>T:.,1,1,1,IVS8,IVS8,IVS8,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1437465,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1437144,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1434029,Yes,c.423C>G:p.C141W,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1439049,Yes,c.853G>C:p.E285Q,2,2,1,EX8,3,3,,,0.0,,,,1.0 Muts/Mb,0.0,0.0,,,0,,,,,,,0,,
1438509,Yes,c.809T>C:p.F270S,2,2,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1439544,Yes,c.782+1delG:.,1,1,1,,,,,,0.0,,,,7.143 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1436063,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1437559,Yes,c.736A>G:p.M246V,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1438787,Yes,c.848dupG:p.T284Hfs*22,1,1,1,EX8,3,3,,,0.0,,,,0.00 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1438121,Yes,c.742C>G:p.R248G,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1435832,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1436150,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1438792,Yes,c.216_217insC:p.V73Rfs*76,1,1,1,EX4,EX4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1437163,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,p.V163L,1,EX1,
1434263,No,,,0,0,,,,p.E746_P753delinsVS,p.E746_P753delinsVS,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1436062,No,,,0,0,,,,p.L747_T751delinsP,p.L747_T751delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1434128,Yes,c.646G>T:p.V216L,2,2,1,Ex6,1,1,,,0.0,,,,,,,,,0,,,,,,,0,,
1436159,No,,,0,0,,,,p.E746_S752delinsV,p.E746_S752delinsV,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1434103,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1434662,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,KIF5B-ALK�ں�,1,EX24:EX20,
1436138,Yes,c.713G>T:p.C238F,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1434494,No,,,0,0,,,,p.H773_V774insH,p.H773_V774insH,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1435436,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1433808,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,4.8 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1434202,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1436769,Yes,c.715A>G:p.N239D,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,EML4-ALK �ں�(��V1/V3),1,EX14��EX20,
1431210,Yes,c.151G>T:p.E51*,1,1,1,EX4,EX4,4,,,0.0,,,,,,,,,0,,,,,,EML4-ALK �ںϣ�V1��,1,EX13:EX20,
1435456,Yes,c.660T>G:p.Y220*,1,1,1,EX6,1,1,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1435267,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1433392,Yes,c.833C>G:p.P278R,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1436479,Yes,ȱʧ,1,1,1,all exon,all exon,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR ����
1437405,No,,,0,0,,,,,,0.0,,,,,,,,p.G12V,1,EX2,,,,,,0,,
1434098,No,,,0,0,,,,p.L858R��p.S768I,p.L858R��p.S768I,1.0,"EX21,EX20",2.0,2.0,,,,,,0,,,,,,,0,,
1433444,Yes,c.707_724delACATGTGTAACAGTTCCT:p.Y236_S241del,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,p.V600E,EX15,,,,0,,
1434276,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1436135,Yes,c.747G>T:p.R249S,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1434275,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1433771,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1432237,No,,,0,0,,,,p.E746_T751delinsVA,p.E746_T751delinsVA,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1434813,No,,,0,0,,,,,,1.0,,,,,,,,,0,,,,,,,0,,
1433018,No,,,0,0,,,,"p.L747_T751delinsP,p.G719S","p.L747_T751delinsP,p.G719S",1.0,EX19��EX18,0.0,0.0,,,,,,0,,,,,,,0,,
1435105,Yes,c.644G>T:p.S215I,2,2,1,EX6,1,1,p.L861Q,p.L861Q,1.0,EX21,2.0,2.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1435082,No,,,0,0,,,,,,0.0,,,,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,p.P490_Q494del,EX12,,,,0,,
1434810,Yes,c.610G>T:p.E204*,1,1,1,EX6,1,1,,,0.0,,,,,,,,,0,,,,,,,0,,
1434595,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.00 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1433008,Yes,c.112C>T:p.Q38*,1,1,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1432389,No,,,0,0,,,,,,0.0,,,,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1429052,Yes,c.930_937delCAACACCA:p.N310Kfs*24,1,1,1,EX9,EX9,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1433017,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1433972,Yes,c.481G>T:p.A161S,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1433347,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1430887,No,,,0,0,,,,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1435131,Yes,c.255_265delTGCACCAGCCC:p.A86Lfs*59,1,1,1,EX4,EX4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1434618,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1433133,No,,,0,0,,,,p.V769_D770insASV,p.V769_D770insASV,1.0,EX15,,,,,,,,0,,,,,,,0,,EGFR����
1435895,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1436232,Yes,c.232_244delGCAGCTCCTACAC:p.A78Rfs*41,1,1,1,EX4,EX4,4,,,0.0,,,,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1430496,No,,,0,0,,,,"p.S768I,p.G719S","p.S768I,p.G719S",1.0,"EX20,EX18",1.0,1.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1430943,No,,,0,0,,,,.L858R,.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1431662,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1430243,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1433144,No,,,0,0,,,," p.L747_P753delinsS,p.T790M"," p.L747_P753delinsS,p.T790M",1.0,"EX19,EX20",0.0,0.0,,,,,,0,,,,,,,0,,
1433839,No,,,0,0,,,,p.L858,p.L858,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1430294,Yes,c.742C>T:p.R248W,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.00 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1431848,No,,,0,0,,,,,,0.0,,,,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1431487,No,,,0,0,,,,p.E746_S752delinsV,p.E746_S752delinsV,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1433062,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1431713,No,,,0,0,,,,p.E746_S752delinsV,p.E746_S752delinsV,1.0,EX19,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1430907,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1431406,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1433843,Yes,c.720T>A:p.S240R,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1429962,Yes,c.646G>A:p.V216M,2,2,1,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1432087,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,IF5B-ALK�ں�,1,EX17:20,
1431635,No,,,0,0,,,,p.H773_V774insH,p.H773_V774insH,1.0,EX20,1.0,1.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1430217,No,,,0,0,,,,p.E746_A750delinsAP,p.E746_A750delinsAP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1423879,No,,,0,0,,,,,,0.0,,,,,,,,,0,,p.G469A,EX11,,,,0,,
1432095,No,,,0,0,,,,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1431052,Yes,c.723delC:p.C242Afs*5,1,1,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ں�,1,EX13:EX20,
1434358,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,1.429 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1429621,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1430914,Yes,c.752T>A:p.I251N,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1429230,No,,,0,0,,,,"p.L861Q,p.G719A","p.L861Q,p.G719A",1.0,"EX21,EX18",2.0,2.0,,,,,,0,,,,,,,0,,
1427272,Yes,c.626_627delGA:p.R209Kfs*6,1,1,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1429735,Yes,c.1006G>T:p.E336*,1,1,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1429292,No,,,0,0,,,,,,0.0,,,,,,,,,0,,p.T488_P492del,EX12,,,,0,,
1427171,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1430233,Yes,c.892G>T:p.E298*,1,1,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1433155,Yes,c.796G>T:p.G266*,1,1,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1430085,No,,,0,0,,,,,,0.0,,,,0.96 Muts/Mb��TMB-L,0.0,0.0,,p.G12C,1,EX2,,,,,,0,,
1428256,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1423362,Yes,c.1027G>T:p.E343*,1,1,1,EX10,EX10,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1424206,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1424629,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1426711,No,,,0,0,,,,,,0.0,,,,23.04Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,EGFR����
1430915,Yes,c.814G>T:p.V272L,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1424723,Yes,c.991C>T:p.Q331*,1,1,1,EX9,EX9,4,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ںϣ�V3,1,EX6��EX20,
1427277,No,,,0,0,,,,,,0.0,,,,,,,,p.G12D,1,EX2,,,,,,0,,
1427987,No,,,0,0,,,,"p.R108K,p.L858R","p.R108K,p.L858R",1.0,"EX3,EX21",,,,,,,,0,,,,,,,0,,
1429945,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1429429,Yes,c.1140delT:p.H380Qfs*42,1,1,1,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1430231,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1432088,Yes,c.991C>T:p.Q331*,1,1,1,EX9,EX9,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1429837,Yes,c.452C>G:p.P151R,2,2,1,EX5,0,0,p.H773_V774insGH,p.H773_V774insGH,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1428855,No,,,0,0,,,,p.S768_V769delinsIL,p.S768_V769delinsIL,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1429961,No,,,0,0,,,,p.D770_N771insSVD,p.D770_N771insSVD,1.0,EX20,1.0,1.0,,,,,p.G12D,1,EX2,,,,,,0,,
1433590,No,,,0,0,,,,,,0.0,,,,8.64 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1395207,Yes,c.844C>T:p.R282W,2,2,1,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1428450,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1430920,Yes,c.747G>C:p.R249S,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1429556,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ںϣ�V3��,1,EX6:EX20,
1428811,No,,,0,0,,,,p.E746_T751delinsA,p.E746_T751delinsA,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1425772,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1429957,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1431218,Yes,c.743G>A:p.R248Q,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1429512,No,,,0,0,,,,,,0.0,,,,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ�V1��,1,EX13��EX20,
1430149,No,,,0,0,,,,,,0.0,,,,,,,,p.G12V,1,EX2,,,,,,0,,
1428624,No,,,0,0,,,,p.S752_I759del,p.S752_I759del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1430879,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1424069,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1428446,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1427630,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1427170,No,,,0,0,,,,p.G719S��p.S768I,p.G719S��p.S768I,1.0,EX18��EX20,,,,,,,,0,,,,,,,0,,
1428361,Yes,c.713G>T:p.C238F,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1428798,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1427110,Yes,c.721T>C:p.S241P,2,2,1,EX7,2,2,p.L747_S752del,p.L747_S752del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1427632,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1429870,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ�V3��,1,,
1428527,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1428688,Yes,c.422G>T:p.C141F,2,2,1,EX5,0,0,,,0.0,,,,,,,,p.G12A,1,EX2,,,,,,0,,
1430598,Yes,c.994-1G>C:.,2,2,1,IVS9,IVS9,4,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1320977,No,,,0,0,,,,p.L858R��p.T790M,p.L858R��p.T790M,1.0,EX21��EX20,2.0,2.0,,,,,p.G12C,1,EX2,,,,,,0,,
1429542,Yes,c.96+1G>A:.,2,2,1,IVS3,IVS3,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1426678,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1284461,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1395103,No,,,0,0,,,,"p.V769M,p.H773_V774insPH","p.V769M,p.H773_V774insPH",1.0,EX20��EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1420761,No,,,0,0,,,,p.K745_E746insLPVAIK,p.K745_E746insLPVAIK,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-,0.0,0.0,,,0,,,,,,,0,,
1428813,No,,,0,0,,,,,,0.0,,,,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1428875,Yes,c.537T>A:p.H179Q,2,2,1,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1423648,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1427675,Yes,c.733G>C:p.G245R,2,2,1,EX7,2,2,,,0.0,,,,8.64Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1422049,Yes,c.560-5_563delCTTAGGTCT:.,1,1,1,IVS5-EX6,IVS5-1,4,p.E746_S752delinsV,p.E746_S752delinsV,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1427553,No,,,0,0,,,,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1421452,Yes,c.548C>G:p.S183*,1,1,1,EX5,0,0,,,0.0,,,,7.09Muts/Mb��ͬ��ͻ�䣦��ͬ��ͻ�䣩��5.67Muts/Mb����ͬ��ͻ�䣩,1.0,,1.0,,0,,,,,,,0,,
1428413,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1428504,Yes,c.376-1G>A:.,0,0,0,IVS4,IVS4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1411751,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,0.0,0.0,,,0,,,,,,,0,,
1408440,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,4.8 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1426832,Yes,c.45_48delTCAG:p.S15Rfs*28,1,1,1,EX2,EX2,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1424440,No,,,0,0,,,,,,0.0,,,,,,,,p.Q61H,1,EX3,,,,,,0,,
1426655,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1428288,Yes,c.770T>C:p.L257P,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1428947,Yes,c.396G>C:p.K132N,2,2,1,EX5,0,0,,,0.0,,,,6.72Muts/Mb��TMB-L,0.0,0.0,,,0,,p.V600E,EX15,,,,0,,
1427748,Yes,c.427G>A:p.V143M,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1425243,Yes,c.902delC:p.P301Qfs*44,1,1,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1426855,Yes,c.1025G>C:p.R342P,2,2,1,EX10,EX10,4,p.V834L��p.L858R,p.V834L��p.L858R,1.0,EX21��EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1426006,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1427058,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1424089,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1428479,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1426290,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1425263,No,,,0,0,,,,,,1.0,,,,,,,,,0,,p.K483E,EX12,,,,0,,
1423410,No,,,0,0,,,,p.D770_N771insGVD,p.D770_N771insGVD,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1427935,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1425734,Yes,c.559G>T:p.G187C,2,2,1,EX5,0,0,,,0.0,,,,15.36Muts/Mb��TMB-H,1.0,,1.0,,0,,p.G466E,EX11,,,,0,,
1424663,No,,,0,0,,,,p.A289V��p.G719A,p.A289V��p.G719A,1.0,EX7��EX18,,,,,,,,0,,,,,,,0,,
1427505,Yes,c.536delA:p.H179Lfs*68,1,1,1,EX5,0,0,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1424735,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1427189,No,,,0,0,,,,"p.E746_A750del,p.T790M","p.E746_A750del,p.T790M",1.0,EX19��EX20,0.0,0.0,,,,,,0,,,,,,,0,,
1423058,Yes,c.853G>A:p.E285K,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1424890,No,,,0,0,,,,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1427527,Yes,c.744delG:p.R249Gfs*96,1,1,1,EX7,2,2,,,0.0,,,,18.24Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1424259,No,,,0,0,,,,,,0.0,,,,,,,,p.G12D,1,EX2,,,,,,0,,
1424585,No,,,0,0,,,,,,0.0,,,,,,,,p.G12F,1,EX2,,,,,,0,,
1420152,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1424905,No,,,0,0,,,,,,0.0,,,,,,,,,0,,p.K601E,EX15,,,,0,,
1426768,No,,,0,0,,,,"p.L858R,p.T790M","p.L858R,p.T790M",1.0,EX20��EX21,1.0,1.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1427300,Yes,c.580C>T:p.L194F,2,2,1,EX6,1,1,,,0.0,,,,32.64 Muts/Mb��TMB-,1.0,,1.0,p.G12D,1,EX2,,,,,,0,,
1425694,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1423027,No,,,0,0,,,,p.L747_A750delins,p.L747_A750delins,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1426730,Yes,c.695T>C:p.I232T,2,2,1,EX7,2,2,,,0.0,,,,0.96Muts/Mb��TMB-L,0.0,0.0,,p.G12V,1,EX2,,,,,,0,,
1425509,Yes,c.820delG:p.V274Ffs*71,1,1,1,EX8,3,3,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1423310,Yes,c.166G>T:p.E56*,1,1,1,EX4,EX4,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1424458,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1426515,Yes,c.715A>G:p.N239D,2,2,1,EX7,2,2,,,0.0,,,,12.48Muts/Mb��TMB-H,1.0,,1.0,p.G12C,1,EX2,,,,,,0,,
1425776,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1425086,No,,,0,0,,,,p.L858R��p.S720,p.L858R��p.S720,1.0,EX18��EX21,,,,,,,,0,,,,,,,0,,
1427283,Yes,c.733G>A:p.G245S,2,2,1,EX7,2,2,,,0.0,,,,6.72 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1425450,Yes,c.532delC:p.H178Tfs*69,1,1,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,EGFR����
1424969,No,,,0,0,,,,,,0.0,,,,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ�V1)��EIF2AK3-ALK�ں�,1,EX13��EX20��EX14��EX18,
1422513,Yes,c.712T>C:p.C238R,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1403683,Yes,c.1073A>T:p.E358V,2,2,1,EX10,EX10,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1423752,Yes,c.645T>A:p.S215R,2,2,1,EX6,1,1,,,0.0,,,,14.4 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1422257,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1420140,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1421818,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1422160,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1424916,No,,,0,0,,,,p.L747_S752delinsQH,p.L747_S752delinsQH,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1424692,Yes,c.427G>A:p.V143M,2,2,1,EX5,0,0,p.L747_A755delinsAT,p.L747_A755delinsAT,1.0,EX19,0.0,0.0,5.76Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1420703,Yes,c.581T>G:p.L194R,2,2,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1425502,Yes,c.472C>G:p.R158G,2,2,1,EX5,0,0,,,0.0,,,,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1421746,Yes,c.1123C>T:p.Q375*,1,1,1,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1423920,Yes,c.1049T>C:p.L350P,2,2,1,EX10,EX10,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,4.8Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1422854,Yes,c.818G>T:p.R273L,2,2,1,EX8,3,3,p.L747_A751de,p.L747_A751de,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1423018,Yes,c.481G>T:p.A161S,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1389537,Yes,c.701A>G:p.Y234C,2,2,1,EX7,2,2,,,0.0,,,,7.68Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1424145,Yes,c.722C>T:p.S241F,2,2,1,EX7,2,2,,,0.0,,,,,,,,p.G12D,1,EX2,,,,,,0,,
1422953,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ���V1/V3��,1,EX7��EX20,
1421468,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1423854,Yes,c.559+1G>A:.,1,1,1,IVS5,IVS5,4,,,0.0,,,,10.56 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1412214,No,,,0,0,,,,p.L858,p.L858,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1422862,Yes,c.398T>A:p.M133K,2,2,1,EX5,0,0,,,0.0,,,,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1423380,No,,,0,0,,,,"p.L858R,p.V834L","p.L858R,p.V834L",1.0,"EX21,EX21",2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1425887,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ�E6��A20��,1,E6:A20,
1420458,Yes,c.637C>T:p.R213*,1,1,1,EX6,1,1,,,0.0,,,,,,,,,0,,,,,,,0,,EGFR����
1422382,Yes,c.892G>T:p.E298*,1,1,1,EX8,3,3,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1417823,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ں�,1,EX14:EX20,
1421339,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1419825,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,p.G12V,1,EX2,,,,,,0,,
1423466,Yes,c.814G>A:p.V272M,2,2,1,EX8,3,3,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1423207,No,,,0,0,,,,,,0.0,,,,,0.0,0.0,,,0,,,,,,,0,,
1421521,Yes,c.743_744delGGinsTT:p.R248L,2,2,1,EX7,2,2,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1423757,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1405417,Yes,c.487T>C:p.Y163H,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1422139,No,,,0,0,,,,p.V769_D770insASV,p.V769_D770insASV,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1421827,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1423458,Yes,c.436T>G:p.W146G,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1423909,Yes,c.727_732delATGGGC:p.M243_G244del,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1421453,No,,,0,0,,,,p.L861Q,p.L861Q,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1421466,Yes,c.535C>T:p.H179Y,2,2,1,EX5,0,0,p.T751_I759delinsN,p.T751_I759delinsN,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1423245,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1420780,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1420770,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ںϣ�V3��,1,EX6:EX20,
1421026,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����������
1419394,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1419429,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1422672,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1418384,Yes,c.528C>G:p.C176W,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1419109,Yes,c.796G>T:p.G266*,1,1,1,EX8,3,3,"p.L833V,p.H835L","p.L833V,p.H835L",1.0,"EX21,EX21",2.0,2.0,,,,,,0,,,,"p.L1195F,p.L1195V","EX18,EX18",,0,,EGFR������MET����
1419452,Yes,c.800G>A:p.R267Q,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1400919,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1418379,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1418443,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1419870,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1420165,Yes,c.811G>A:p.E271K,2,2,1,EX8,3,3,"p.G719S,p.E709K","p.G719S,p.E709K",1.0,"EX18,EX18",,,,,,,,0,,,,,,,0,,
1419851,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,KLC1-ALK�ںϣ�EX9��EX20��,1,EX9��EX20,
1415013,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1418899,Yes,c.472delC:p.R158Afs*12,1,1,1,EX5,0,0,"p.E746_A750del,p.G719A,p.L861R","p.E746_A750del,p.G719A,p.L861R",1.0,"EX19,EX18,EX21",0.0,0.0,,,,,,0,,,,,,,0,,
1421483,Yes,c.389T>G:p.L130R,2,2,1,EX5,0,0,"p.L858R,p.T790M","p.L858R,p.T790M",1.0,"EX21,EX20",2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1421480,Yes,c.731G>A:p.G244D,2,2,1,EX7,2,2,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1420787,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1420612,Yes,c.94_96+15delCTGGTAAGGACAAGGGTT:.,1,1,1,EX3-IVS3,EX3-IVS3,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1422041,Yes,c.853G>A:p.E285K,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,p.E340K,1,EX27,
1422166,Yes,c.577C>A:p.H193N,2,2,1,EX6,1,1,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1422653,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1421493,Yes,c.659A>G:p.Y220C,2,2,1,EX6,1,1,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,5.76Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1421089,Yes,c.743G>A:p.R248Q,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1417821,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1421673,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,4.8Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1419547,No,,,0,0,,,,,,0.0,,,,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1415250,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1418189,No,,,0,0,,,,p.E746_S752delinsV,p.E746_S752delinsV,1.0,EX19,0.0,0.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1418858,Yes,c.314G>T:p.G105V,2,2,1,EX4,EX4,4,,,0.0,,,,14.4 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1394650,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1419090,No,,,0,0,,,,,,0.0,,,,4.8 Muts/Mb��TMB-L,0.0,0.0,,p.G12C,1,EX2,,,,,,0,,
1418491,Yes,c.524G>A:p.R175H,2,2,1,EX5,0,0,p.E746_A750del:p.E513K,p.E746_A750del:p.E513K,1.0,EX19:EX13,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1419605,No,,,0,0,,,,,,0.0,,,,15.36Muts/Mb��TMB-H,1.0,,1.0,p.G12D,1,EX2,,,,,,0,,
1417444,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1418656,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1418705,Yes,c.713G>A:p.C238Y,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1419716,No,,,0,0,,,,p.G12V,p.G12V,1.0,EX2,,,,,,,,0,,,,,,,0,,
1418152,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1418975,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1416425,No,,,0,0,,,,,,0.0,,,,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,p.E42*,1,EX1,
1419087,Yes,c.849delC:p.T284Qfs*61,1,1,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1419612,Yes,c.880G>T:p.E294*,1,1,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,EGFR����
1415507,No,,,0,0,,,,p.L858R:p.S768I,p.L858R:p.S768I,1.0,EX21:EX20,2.0,2.0,0.00Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1421380,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1414950,Yes,c.725G>A:p.C242Y,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1416168,Yes,c.991C>T:p.Q331*,1,1,1,EX9,EX9,4,p.L747_S752del,p.L747_S752del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1416634,No,,,0,0,,,,,,0.0,,,,,,,,,0,,p.L597Q,EX15,,,,0,,
1418444,Yes,"c.527G>A:p.C176Y,c.747G>T:p.R249S",2,2,1,EX5:EX7,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1419431,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1415572,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1418194,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1420601,Yes,c.641A>G:p.H214R,2,2,1,EX6,1,1,,,0.0,,,,,,,,p.G12A,1,EX2,,,,,,0,,
1420324,Yes,c.711G>T:p.M237I,2,2,1,EX7,2,2,,,0.0,,,,,,,,p.C188*,1,EX4,p.D594N,EX15,,,,0,,
1417524,No,,,0,0,,,,p.A289V:p.L858R,p.A289V:p.L858R,1.0,EX7:EX21,,,,,,,,0,,,,,,,0,,
1417151,No,,,0,0,,,,,,0.0,,,,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1418825,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1420092,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1417694,Yes,c.375_375+6delGGTCAGT:.,1,1,1,EX4-IVS4,EX4-IVS4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1418895,Yes,c.818G>T:p.R273L,2,2,1,EX8,3,3,p.L858R:p.L718Q,p.L858R:p.L718Q,1.0,EX21:EX18,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1418918,Yes,c.659A>G:p.Y220C,2,2,1,EX6,1,1,,,0.0,,,,15.36 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,p.S1053V,1,EX19,
1421088,Yes,c.949C>T:p.Q317*,1,1,1,EX9,EX9,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1418649,Yes,c.388C>G:p.L130V,2,2,1,EX5,0,0,p.L838V:p.L858R,p.L838V:p.L858R,1.0,EX21:EX21,2.0,2.0,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1418407,Yes,c.637C>T:p.R213*,1,1,1,EX6,1,1,,,0.0,,,,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,p.E25Q,EX2,,0,,
1418453,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1415748,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1417420,Yes,c.856G>A:p.E286K,2,2,1,EX8,3,3,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1420499,Yes,c.994-2A>G:.,0,0,0,IVS9,IVS9,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1416485,Yes,c.527G>A:p.C176Y,2,2,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1417214,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,p.I865E,EX12,,0,,
1417950,Yes,c.961A>T:p.K321*,1,1,1,EX9,EX9,4,p.L747_T751delinsQ,p.L747_T751delinsQ,1.0,EX19,0.0,0.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1418229,Yes,c.749C>T:p.P250L,2,2,1,EX7,2,2,p.L747_T751delinsP,p.L747_T751delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1419033,No,,,0,0,,,,p.L858R:p.L833V,p.L858R:p.L833V,1.0,EX21:EX21,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1417321,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1416579,Yes,c.514G>T:p.V172F,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1415581,Yes,c.672+2T>G:.,1,1,1,IVS5,IVS5,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1419264,Yes,c.743G>A:p.R248Q,2,2,1,EX7,2,2,p.L747_T750delinsP,p.L747_T750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1415749,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1419126,Yes,c.641A>G:p.H214R,2,2,1,EX6,1,1,,,0.0,,,,,,,,,0,,,,,,,0,,
1418970,No,,,0,0,,,,p.L858R:p.T790M,p.L858R:p.T790M,1.0,EX21:EX20,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1414653,No,,,0,0,,,,,,0.0,,,,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1417857,Yes,c.792_794delACT:p.L265del,2,2,1,EX8,3,3,,,0.0,,,,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1417837,Yes,c.817C>T:p.R273C,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1417854,Yes,c.924_930delGCCCAAC:p.P309Tfs*34,1,1,1,EX9,EX9,4,,,0.0,,,,,,,,p.G12D,1,EX2,,,,,,0,,
1415851,Yes,c.983delT:p.F328Sfs*17,1,1,1,EX9,EX9,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1415219,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1414755,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1414551,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1412574,Yes,c.514G>T:p.V172F,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1405852,Yes,c.733G>A:p.G245S,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1417160,Yes,c.818G>A:p.R273H,2,2,1,EX8,3,3,,,0.0,,,,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,p.V50DE,EX15,,,,0,,
1417128,No,,,0,0,,,,p.G719A:p.S720F,p.G719A:p.S720F,1.0,EX18:EX18,,,,,,,,0,,,,,,,0,,
1416267,No,,,0,0,,,,p.E747_S753delinsS,p.E747_S753delinsS,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1414709,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1414883,No,,,0,0,,,,,,0.0,,,,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,p.V600E,EX15,,,,0,,
1416551,No,,,0,0,,,,p.V834L:p.L858R,p.V834L:p.L858R,1.0,EX21:EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1415277,Yes,c.610G>T:p.E204*,1,1,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1417331,Yes,c.920-2A>T:.,0,0,0,IVS8,IVS8,4,,,0.0,,,,8.64Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1415712,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1415511,Yes,c.818G>T:p.R273L,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,p.Y1295C,EX20,,0,,
1416627,Yes,c.586C>T:p.R196*,1,1,1,,,,,,0.0,,,,EX6,,,,,0,,,,,,,0,,
1415855,Yes,c.404G>A:p.C135Y,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1411700,Yes,c.538G>T:p.E180*,1,1,1,EX5,0,0,P.E687Q,P.E687Q,1.0,EX17,,,,,,,p.G12S,1,EX2,,,,,,0,,
1414089,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1415608,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1414733,No,,,0,0,,,,,,1.0,,,,,,,,,0,,,,,,,0,,
1413616,Yes,c.402T>G:p.F134L,2,2,1,EX5,0,0,p.L858R:p.S720F,p.L858R:p.S720F,1.0,EX21:EX18,2.0,2.0,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,p.P1543S,1,EX29,
1416260,No,,,0,0,,,,p.L858R:p.S784Y,p.L858R:p.S784Y,1.0,EX21:EX20,2.0,2.0,0.00Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1415771,No,,,0,0,,,,,,0.0,,,,,,,,p.G12V,1,EX2,,,,,,0,,
1414066,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1414649,Yes,c.738G>C:p.M246I,2,2,1,EX7,2,2,p.H773_V774insPH,p.H773_V774insPH,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1415126,Yes,c.949C>T:p.Q317*,1,1,1,EX9,EX9,4,p.E747_A750delinsP,p.E747_A750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1414756,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1416238,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,p.S337L,EX8,,,,0,,
1415223,No,,,0,0,,,,,,0.0,,,,,,,,p.G12A,1,EX2,,,,,,0,,
1415366,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1411187,Yes,c.723delC:p.C242Afs*5,1,1,1,EX7,2,2,,,0.0,,,,,,,,,0,,p.G465A,EX11,,,,0,,
1414126,Yes,c.659A>G:p.Y220C,2,2,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1414036,No,,,0,0,,,,p.G719A:p.LB33V:p.T790M,p.G719A:p.LB33V:p.T790M,1.0,EX18:EX21:EX20,,,6.72Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1412909,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,p.G12D,1,EX2,,,,,,0,,
1414648,No,,,0,0,,,,p.E747_S753delinsS,p.E747_S753delinsS,1.0,EX19,0.0,0.0,,,,,,0,,p.S579G,EX14,.,IVS14,,0,,
1410928,Yes,c.733G>T:p.G245C,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1407841,Yes,c.463_468delACCCGC:p.T155_R156del,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1410291,No,,,0,0,,,,p.E746_S751delinsA,p.E746_S751delinsA,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1410340,No,,,0,0,,,,p.G719S:p.E709A,p.G719S:p.E709A,1.0,EX18:EX18,,,,,,,,0,,,,,,,0,,
1410468,Yes,"c.590T>A:p.V197E,c.422G>A:p.C141Y",2,2,1,EX6:EX5,1,1,,,0.0,,,,8.64Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1412267,No,,,0,0,,,,p.R776H:p.L858R,p.R776H:p.L858R,1.0,EX20:EX21,1.0,1.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1405117,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,0.0,0.0,,,0,,,,,,,0,,
1411053,Yes,c.469G>T:p.V157F,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1413832,No,,,0,0,,,,,,0.0,,,,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1414219,Yes,c.991C>T:p.Q331*,1,1,1,EX9,EX9,4,,,0.0,,,,9.6Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1413834,Yes,c.844C>T:p.R282W,2,2,1,,,,,,0.0,,,,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1400522,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1413882,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1413810,Yes,c.733G>A:p.G245S,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1413525,Yes,c.817C>T:p.R273C,2,2,1,EX8,3,3,,,0.0,,,,TMB-L��2.88Muts/Mb,0.0,0.0,,,0,,,,,,,0,,
1413081,Yes,c.725G>A:p.C242Y,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,EGFR����
1414022,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1414435,Yes,c.565G>C:p.A189P,2,2,1,EX6,1,1,,,0.0,,,,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1412414,Yes,c.714T>G:p.C238W,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,0.0,0.0,,,0,,,,,,,0,,
1411431,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1405125,No,,,0,0,,,,,,0.0,,,,,,,,p.G12D,1,EX2,,,,,,0,,
1412403,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,TMB-L��0.0Muts/Mb,0.0,0.0,,,0,,,,,,,0,,
1412269,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1405757,Yes,c.775G>T:p.D259Y,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1412025,Yes,c.919+1G>A:.,1,1,1,IVS8,IVS8,4,,,0.0,,,,,,,,,0,,,,,,p.S691R,1,EX12,
1412406,Yes,c.546_550delCTCAG:p.C182*fs*1,1,1,1,EX5,0,0,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1412812,Yes,c.920-2A>G:.,0,0,0,IVS8,IVS8,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1411653,Yes,c.659A>G:p.Y220C,2,2,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1412257,Yes,c.645T>A:p.S215R,2,2,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,TMB-L��3.84Muts/Mb,0.0,0.0,,,0,,,,,,,0,,
1411747,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1355273,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1411006,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1385554,No,,,0,0,,,,p.T747_I750delinsP,p.T747_I750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1412744,Yes,c.818G>A:p.R273H,2,2,1,EX8,3,3,,,0.0,,,,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1412610,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1411193,No,,,0,0,,,,,,0.0,,,,,,,,p.L19F,1,EX2,p.L567V,EX14,,,p.L355M,1,EX4,
1411553,Yes,c.782+1G>T:.,1,1,1,IVS7,IVS7,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1411652,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1411790,Yes,c.514G>T:p.V172F,2,2,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1409639,Yes,c.535C>T:p.H179Y,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1411104,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1411126,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1410471,No,,,0,0,,,,,,0.0,,,,4.8Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1410349,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1408779,Yes,c.759_762delCATC:p.I254Sfs*90,1,1,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1411279,No,,,0,0,,,,p.L861Q,p.L861Q,1.0,EX21,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1411189,Yes,c.224_227delCTGC:p.P75Hfs*47,1,1,1,Ex4,Ex4,4,,,0.0,,,,5.76Muts/Mb��TMB-L,0.0,0.0,,,0,,p.G466E,EX11,,,,0,,
1410539,No,,,0,0,,,,,,0.0,,,,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,,,p.Q348*,EX2,,0,,
1409210,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1410462,Yes,c.404G>T:p.C135F,2,2,1,EX5,0,0,p.T747_I752delinsQH,p.T747_I752delinsQH,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1410457,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1408140,No,,,0,0,,,,p.A750P:p.E746_E749delinsQ,p.A750P:p.E746_E749delinsQ,1.0,EX19:EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1411341,Yes,c.920-7_930delTTCCTAGCACTGCCCAAC:.,1,1,1,IVSB-EX9,IVSB-EX9,4,p.H773_V774insNPH,p.H773_V774insNPH,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1399832,Yes,c.733G>T:p.G245C,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1407472,Yes,c.1027G>T:p.E343*,1,1,1,EX10,EX10,4,,,0.0,,,,14.4Muts/Mb��TMB-H,1.0,,1.0,,0,,,,.,IVS13,,0,,
1410944,No,,,0,0,,,,,,0.0,,,,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1408641,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1410047,Yes,c.713G>T:p.C238F,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,.,IVS14,,0,,EGFR����
1405168,Yes,c.838delA:p.R280Efs*65,1,1,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1382880,Yes,c.743G>A:p.R248Q,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1411073,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1410368,Yes,c.481G>A:p.A161T,2,2,1,EX5,0,0,,,0.0,,,,,,,,p.G12V,1,EX2,,,,,,0,,
1405280,Yes,c.574C>T:p.Q192*,1,1,1,EX6,1,1,,,0.0,,,,5.76Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1408341,Yes,c.377A>G:p.Y126C,2,2,1,EX5,0,0,,,0.0,,,,TMB-H��28.8 Muts/Mb,1.0,,1.0,,0,,p.G442Wfs*2,EX11,,,p.S312C:p.H458Y,1,EX3:EX6,
1408552,Yes,c.817C>T:p.R273C,2,2,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1405221,Yes,"c.839_842delGAGA:p.R280Tfs*64,c.560-1G>A:.",2,2,1,EX8:IV55,3,3,,,0.0,,,,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1409414,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1408374,Yes,c.844C>T:p.R282W,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1409422,No,,,0,0,,,,p.E746_T751delinsA,p.E746_T751delinsA,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1408493,Yes,c.376-2delA:.,2,2,1,IVS4,IVS4,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1409227,Yes,c.1015G>T:p.E339*,1,1,1,EX10,EX10,4,,,0.0,,,,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,.:p.A8Cfs*20,IVS13:EX2,,0,,
1408597,Yes,c.818G>A:p.R273H,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1408946,Yes,c.991C>T:p.Q331*,1,1,1,,,,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1408477,Yes,c.751A>C:p.I251L,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,p.D94H,EX2,,0,,EGFR����
1408967,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,p.G12C,1,EX2,,,,,,0,,
1404874,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1405089,No,,,0,0,,,,,,0.0,,,,,,,,p.Q61H,1,EX3,,,,,,0,,
1405103,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1367705,No,,,0,0,,,,,,0.0,,,,,,,,p.G12D,1,EX2,,,,,,0,,
1404909,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1403663,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1396724,Yes,c.623A>T:p.D208V,2,2,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,4.8Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1401965,Yes,c.377A>G:p.Y126C,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1404323,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,p.A1363T,EX21,,0,,
1397205,Yes,c.958A>T:p.K320*,1,1,1,EX9,EX9,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1396740,Yes,c.326delT:p.F109Sfs*14,1,1,1,EX4,EX4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,p.G715R,1,EX12,
1387243,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1407085,Yes,c.406C>G:p.Q136E,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1401967,Yes,c.559+1G>A:.,1,1,1,IVS5,IVS5,4,,,0.0,,,,14.4Muts/Mb��TMB-H,1.0,,1.0,p.G12C,1,EX2,,,,,,0,,
1403696,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1406802,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1406648,Yes,c.586C>T:p.R196*,1,1,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1408168,Yes,c.747G>C:p.R249S,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1403653,No,,,0,0,,,,p.E746_S752delinsV,p.E746_S752delinsV,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1407360,Yes,c.461G>T:p.G154V,2,2,1,EX5,0,0,,,0.0,,,,,,,,p.G12V,1,EX2,,,,,,0,,
1402270,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1406285,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1406840,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1406457,Yes,c.473_474delGCinsTT:p.R158L,2,2,1,EX5,0,0,,,0.0,,,,,,,,p.A18D,1,EX2,,,,,p.G919R,1,EX16,
1407650,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX21,2.0,2.0,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1405662,No,,,0,0,,,,p.L861Q,p.L861Q,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1396212,Yes,c.96+1G>T:.,1,1,1,IVS3,IVS3,4,,,0.0,,,,,,,,p.G12C,1,EX2,,,p.D1373V,EX21,,0,,
1405977,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1406456,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1408167,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1407660,Yes,c.430_437delCAGCTGTG:p.Q144Gfs*2,1,1,1,EX5,0,0,,,0.0,,,,11.52Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1390441,Yes,"c.524G>T:p.R175L,c.466delC:p.R156Afs*14",1,1,1,EX5:EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1406464,No,,,0,0,,,,p.L858R��p.S768I,p.L858R��p.S768I,1.0,"EX21,EX20",2.0,2.0,,,,,,0,,,,,,,0,,
1405152,Yes,c.783-1G>T:.,2,2,1,IVS7,IVS7,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1405997,No,,,0,0,,,,p.E746_P753delinsVS,p.E746_P753delinsVS,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1404021,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1404030,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1405424,No,,,0,0,,,,,,0.0,,,,8.64 Muts/Mb��TMB-L,0.0,0.0,,p.G12D,1,EX2,,,,,,0,,
1406647,No,,,0,0,,,,"p.L858R,p.K860I","p.L858R,p.K860I",1.0,EX21,2.0,2.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1403517,Yes,c.989T>G:p.L330R,2,2,1,EX9,EX9,4,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1403028,Yes,c.681dupT:p.D228*fs*1,1,1,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,"EX12,EX19",,,,,,,,0,,,,,,,0,,
1389464,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1402579,Yes,c.723delC:p.C242Afs*5,1,1,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1397016,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1398761,Yes,c.97-2A>T:.,0,0,0,IVS3,IVS3,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1402450,No,,,0,0,,,,,,0.0,,,,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1404299,No,,,0,0,,,,p.H773_V774insNPH,p.H773_V774insNPH,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1403826,Yes,"c.902-903insC>T:p.G302Rfs*4,c.991C>T:P.Q331*",2,2,1,"EX8,EX9",3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1405783,Yes,c.927_931delCAACAinsG:p.N310Tfs*34,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1404180,Yes,c.1009C>T:p.R337C,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1404695,Yes,c.423C>G:p.C141W,2,2,1,EX5,0,0,,,0.0,,,,,,,,p.G12A,1,EX2,,,,,,0,,
1405975,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1400677,No,,,0,0,,,,,,0.0,,,,,,,,,0,,p.V600E,EX15,,,,0,,
1401036,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1400559,Yes,c.365_371delTGACTTG:p.V122Afs*46,1,1,1,EX4,EX4,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1400246,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1400525,Yes,c.380C>T:p.S127F,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,p.P37Q,1,EX1,
1378858,Yes,c.455delC:p.P152Rfs*18,1,1,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1403831,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1404398,Yes,c.461G>T:p.G154V,2,2,1,EX5,0,0,p.E746_T751delinsL,p.E746_T751delinsL,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1402202,Yes,c.659A>G:p.Y220C,2,2,1,EX6,1,1,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,p.G12D,1,EX2,,,,,,0,,
1400811,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1402839,Yes,c.1045G>T:p.E349*,2,2,1,EX10,EX10,4,,,0.0,,,,,,,,p.G12V,1,EX2,,,,,,0,,
1403342,Yes,c.673-2A>T:.,1,1,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1403486,Yes,c.818G>T:p.R273L,2,2,1,EX8,3,3,,,0.0,,,,10.56Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1401023,No,,,0,0,,,,,,0.0,,,,,0.0,0.0,,,0,,,,,,,0,,
1401834,Yes,c.153_156delACAA:p.E51Dfs*71,1,1,1,EX4,EX4,4,,,0.0,,,,10.56Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1399776,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1400817,No,,,0,0,,,,"p.L858R,p.D1009_D1014del","p.L858R,p.D1009_D1014del",1.0,"EX21,EX25",2.0,2.0,,,,,,0,,,,,,,0,,
1400626,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1401369,Yes,c.614A>T:p.Y205F,2,2,1,EX6,1,1,"p.L858R,p.R889G","p.L858R,p.R889G",1.0,"EX21,EX22",2.0,2.0,,,,,,0,,,,,,,0,,
1402895,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1399011,No,,,0,0,,,,,,0.0,,,,,,,,,0,,p.K483E,EX12,,,,0,,
1401676,No,,,0,0,,,,,,0.0,,,,,,,,,0,,p.D638N,EX16,,,"EML4-ALK�ںϣ�V3��,ALK-FXJ3(intergenic)",1,"EX6��EX20,EX19intergenic",
1402833,No,,,0,0,,,,p.H850Q,p.H850Q,1.0,EX21,2.0,2.0,,,,,p.G12C,1,EX2,,,,,,0,,
1400209,No,,,0,0,,,,p.V769_D770insASV,p.V769_D770insASV,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1395071,Yes,c.659A>G:p.Y220C,2,2,1,EX6,1,1,"p.L747_P753delinsS,p.L747S","p.L747_P753delinsS,p.L747S",1.0,"EX19,EX19",0.0,0.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1398718,No,,,0,0,,,,"p.L861R,p.L62R","p.L861R,p.L62R",1.0,"EX21,EX2",2.0,2.0,,,,,,0,,,,,,,0,,
1399536,Yes,c.779_782+29delCCAGGTCAGGAGCCACTTGCCACCCTGCACACT:.,1,1,1,EX7-IVS7,3,3,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1399654,Yes,c.329G>T:p.R110L,2,2,1,EX4,EX4,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1401520,Yes,c.794T>G:p.L265R,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1401366,Yes,c.844C>T:p.R282W,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1397720,No,,,0,0,,,,"p.L747_T751del,p.V834L,p.K754Q","p.L747_T751del,p.V834L,p.K754Q",1.0,"EX19,EX21,EX19",0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1395888,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1399395,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1398775,Yes,"c.548C>G:p.S183*,c.422G>A:p.C141Y",2,2,1,"EX5,EX5",0,0,,,0.0,,,,7.68Muts/Mb��TMB-L,0.0,0.0,,p.G12R,1,EX2,,,,,,0,,
1394051,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1397261,Yes,c.1015G>T:p.E339*,1,1,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1397456,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,KRAS����
1400195,Yes,c.610G>T:p.E204*,1,1,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1396868,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,p.T1012M,1,,
1397002,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1398762,Yes,c.830G>T:p.C277F,2,2,1,EX8,3,3,,,0.0,,,,,,,,p.G12A,1,EX2,,,,,,0,,
1400262,Yes,c.595_596delGGinsTT:p.G199L,2,2,1,EX6,1,1,,,0.0,,,,,,,,,0,,,,,,,0,,
1398740,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1398073,No,,,0,0,,,,p.H773_V774insH,p.H773_V774insH,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1396711,Yes,c.745A>T:p.R249W,2,2,1,EX7,2,2,p.L861Q,p.L861Q,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1396080,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1398211,Yes,c.216delC:p.V73Wfs*50,1,1,1,EX4,EX4,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1398390,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1399729,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1396760,Yes,c.841G>C:p.D281H,2,2,1,EX8,3,3,"p.E746_A750del,p.T594N","p.E746_A750del,p.T594N",1.0,"EX19,EX15",0.0,0.0,,,,,,0,,,,,,,0,,
1395942,Yes,c.817C>T:p.R273C,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1398687,No,,,0,0,,,,,,0.0,,,,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1396733,Yes,c.469G>C:p.V157L,2,2,1,EX5,0,0,"p.L747_P753delinsS,p.L747S","p.L747_P753delinsS,p.L747S",1.0,"EX19,EX19",0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1396732,Yes,c.380C>G:p.S127C,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1395137,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,ȱʧ,1,all exon,
1396603,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1392632,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ںϣ���V1/V3),1,EX14��EX20,
1393610,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1384932,Yes,c.818G>T:p.R273L,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1390213,No,,,0,0,,,,"p.L858R,p.N57D","p.L858R,p.N57D",1.0,EX21��EX2,2.0,2.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1384508,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1386445,Yes,"c.706T>C:p.Y236H,c.406C>T:p.Q136*",2,2,1,"EX7,EX5",2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����������
1387677,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1385197,Yes,c.517G>A:p.V173M,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1384479,Yes,"c.722C>T:p.S241F,c.271dupT:W91Lfs*58",1,1,1,"EX7,EX4","2,EX4",2,,,0.0,,,,,,,,,0,,,,,,,0,,
1384956,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ں�(V1),1,EX13:EX20,
1377434,No,,,0,0,,,,p.E746_T751delinsA,p.E746_T751delinsA,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1390503,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,"EML4-ALK�ںϣ�V1��,ALK-PNO1�ں�",1,"EX13:EX20,EX18:EX6",
1377342,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,5.76Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1374965,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1379105,Yes,c.1148_1160delTCATGTTCAAGAC:p.L383Qfs*35,1,1,1,EX11,EX11,4,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1397357,Yes,c.783-2A>T:.,2,2,1,IVS7,IVS7,4,,,0.0,,,,11.52��ͻ��/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1396892,Yes,c.273G>A:p.W91*,1,1,1,EX4,EX4,4,,,0.0,,,,9.6Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1394897,Yes,c.454C>T:p.P152S,2,2,1,EX5,0,0,"p.L858R,p.N771delinsGF","p.L858R,p.N771delinsGF",1.0,"EX21,EX20",2.0,2.0,3.84��ͻ��/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1394215,Yes,c.725G>T:p.C242F,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1390058,No,,,0,0,,,,,,0.0,,,,2.88��ͻ��/Mb��TMB-L,0.0,0.0,,p.G12R,1,EX2,,,,,,0,,
1396024,No,,,0,0,,,,p.L861Q,p.L861Q,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1395222,Yes,c.1009C>T:p.R337C,2,2,1,EX10,EX10,4,,,0.0,,,,1.92��ͻ��/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ں�(V1),1,EX13��EX20,
1396725,Yes,"c.818G>A:p.R273H,c.392A>G:p.N131S",2,2,1,EX8��EX5,3��0,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1395311,Yes,c.722C>A:p.S241Y,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1394390,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1394469,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,"EML4-ALK�ں�(V3),ALK-C3arf67(intergenic)",1,"EX6:EX20,EX19:intergenic",
1395024,Yes,c.97dupT:p.S33Ffs*10,1,1,1,EX4,EX4,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1297497,Yes,c.524G>A:p.R175H,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1392454,Yes,c.916C>T:p.R306*,1,1,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1393479,Yes,c.818G>T:p.R273L,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1394648,Yes,c.736A>G:p.M246V,2,2,1,EX7,2,2,p.K745_E746insVPVAIK,p.K745_E746insVPVAIK,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1395026,No,,,0,0,,,,,,0.0,,,,,,,,p.G13C,1,EX2,,,,,,0,,
1392281,Yes,c.485T>A:p.I162N,2,2,1,EX5,0,0,"p.L747_T751del,p.L747S","p.L747_T751del,p.L747S",1.0,"EX19,EX19",0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1394213,Yes,c.380C>T:p.S127F,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,"EML4-ALK�ںϣ�V3��,ALK-KCNQ5�ں�",1,"EX6:EX20,EX19:EX2",
1395382,Yes,c.718A>T:p.S240C,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1393499,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1392526,No,,,0,0,,,,,,0.0,,,,12.48Muts/Mb��TMB-H,1.0,,1.0,p.G12C,1,EX2,,,,,,0,,
1392884,No,,,0,0,,,,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1391242,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1392841,No,,,0,0,,,,"p.G719A,p.E709A","p.G719A,p.E709A",1.0,"EX18,EX18",,,,,,,,0,,,,,,,0,,
1389026,No,,,0,0,,,,,,0.0,,,,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1391726,Yes,c.817C>T:p.R273C,2,2,1,,,,,,0.0,,,,,0.0,0.0,,,0,,,,,,,0,,
1395025,Yes,c.742C>G:p.R248G,2,2,1,EX7,2,2,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����������
1392452,Yes,c.613dupT:p.Y205Lfs*4,1,1,1,EX6,1,1,"p.L858R,p.T790M,p.A1118V","p.L858R,p.T790M,p.A1118V",1.0,"EX21,EX20,EX28",2.0,2.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1393451,Yes,c.743G>T:p.R248L,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,TMB-L,,,,,0,,,,,,,0,,EGFR����������
1390803,Yes,c.743G>A:p.R248Q,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1392206,Yes,c.580C>T:p.L194F,2,2,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����������
1394027,Yes,c.880delG:p.E294Sfs*51,1,1,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,4.8Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1391241,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1389270,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1390865,Yes,c.701A>G:p.Y234C,2,2,1,EX7,2,2,,,0.0,,,,8.64Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1391564,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1392453,No,,,0,0,,,,,,0.0,,,,8.64 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1390319,Yes,c.725G>C:p.C242S,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1390462,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1390866,Yes,c.994-3_998delCAGATCCG:.,2,2,1,IVS9-EX10,IVS9-EX10,4,"p.L858R,p.T790M,p.K860l,p.K860l","p.L858R,p.T790M,p.K860l,p.K860l",1.0,"EX21,EX20,EX21,EX21",2.0,2.0,,,,,,0,,,,,,,0,,
1389339,Yes,c.814G>A:p.V272M,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1387670,No,,,0,0,,,,"p.L858R,p.E709V","p.L858R,p.E709V",1.0,"EX21,EX18",2.0,2.0,,,,,,0,,,,,,,0,,
1390867,No,,,0,0,,,,"p.E746_A750del,p.G42D","p.E746_A750del,p.G42D",1.0,"EX19,EX2",0.0,0.0,,,,,,0,,,,,,,0,,
1385809,No,,,0,0,,,,"p.T790M,p.L858R","p.T790M,p.L858R",1.0,"EX20,EX21",1.0,1.0,,,,,,0,,,,,,,0,,
1386533,Yes,c.641A>G:p.H214R,2,2,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1389214,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1386032,Yes,c.731G>T:p.G244V,2,2,1,EX7,2,2,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1389534,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1387182,Yes,c.376-1G>C:.,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1388279,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1387056,Yes,c.722C>T:p.S241F,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1387324,Yes,c.1028_1038delAGCTGAATGAG:p.E343Gfs*35,1,1,1,EX10,EX10,4,,,0.0,,,,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,"EML4-ALK�ںϣ�V3��,EML4-ALK�ںϣ���V1/V3��",1,,"EX6:EX20,EX7:EX20"
1385824,Yes,"c.725G>A:p.C242Y,c.454_466delCCGCCCGGCACCC:p.P152Afs*14",2,2,1,"EX7,EX5",2,2,,,0.0,,,,,,,,,0,,,,,,"EML4-ALK�ںϣ���V1/V3��,ALK-PNPT1",1,,"EX21:EX20,EX19:EX27"
1386505,Yes,c.641A>G:p.H214R,2,2,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,4.8Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����������
1388163,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1384726,Yes,c.821T>G:p.V274G,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1384478,Yes,c.602delT:p.L201Cfs*46,1,1,1,,,,EX6,EX6,1.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,p.G12V,1,EX2,,,,,,0,,
1386806,Yes,c.388delC:p.L130Sfs*40,1,1,1,,,,EX5,EX5,1.0,,,,11.52Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1383974,No,,,0,0,,,,,,0.0,,,,,,,,p.G12D,1,EX2,,,,,,0,,
1384561,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1380969,Yes,c.1136G>A:p.R379H,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1381001,Yes,c.814G>T:p.V272L,2,2,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1382202,No,,,0,0,,,,p.K745_E746insIPVAIK,p.K745_E746insIPVAIK,1.0,EX19,0.0,0.0,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1384480,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1363947,Yes,c.574C>T:p.Q192*,1,1,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1382042,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1383813,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1385827,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1384227,Yes,c.331delC:p.L111Wfs*12,1,1,1,EX4,EX4,4,,,0.0,,,,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,EML4-ALK�ںϣ�V1��,1,EX13:EX20,
1379092,No,,,0,0,,,,,,0.0,,,,,,,,,0,,p.V600E,EX15,,,,0,,
1380453,Yes,c.1015G>T:p.E339*,1,1,1,EX10,EX10,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1380585,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1378555,Yes,c.830G>T:p.C277F,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1382730,Yes,c.581T>G:p.L194R,2,2,1,,,,p.E746_A750del,p.E746_A750del,1.0,,,,,,,,,0,,,,,,,0,,EGFR����������
1378489,No,,,0,0,,,,p.D770_N771insSVD,p.D770_N771insSVD,1.0,EX20,1.0,1.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1381487,No,,,0,0,,,,,,0.0,,,,,,,,p.G12D,1,EX2,,,,,,0,,
1382734,No,,,0,0,,,,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1381239,Yes,c.646G>T:p.V216L,2,2,1,EX6,1,1,p.E746_L747delinsIP,p.E746_L747delinsIP,1.0,EX19,0.0,0.0,,,,,p.Y166H,1,EX5,,,,,,0,,
1382733,Yes,c.782+1G>A:.,1,1,1,IVS7,IVS7,4,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1382364,Yes,c.535C>T:p.H179Y,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1382516,Yes,c.853G>A:p.E285K,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1381732,Yes,c.818G>T:p.R273L,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1376853,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1379485,No,,,0,0,,,,,,0.0,,,,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1378649,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1381330,Yes,c.389T>A:p.L130H,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1381919,No,,,0,0,,,,,,0.0,,,,20.16 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,p.W883R,1,EX16,
1379051,Yes,c.796_797delGGinsTT:p.G266L,2,2,1,EX8,3,3,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1375521,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1378292,Yes,c.826G>C:p.A276P,2,2,1,EX8,3,3,,,0.0,,,,13.44Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1365684,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1378293,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����������
1377354,No,,,0,0,,,,,,0.0,,,,7.68Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1378158,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1378451,Yes,c.853G>A:p.E285K,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1380065,No,,,0,0,,,,,,0.0,,,,,,,,,0,,p.N581I,EX15,,,,0,,
1380937,Yes,c.277delC:p.L93Cfs*30,1,1,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1379481,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1379476,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,"PNPT1-ALK�ں�,ALK-GPR75-ASB3�ں�",1,"EX22:EX20,EX19:Promoter",
1377698,Yes,c.734G>T:p.G245V,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1374734,Yes,"c.824G>A:p.C275Y,c.720T>G:p.S240R",2,2,1,"EX8,EX7",3,3,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,,,,,p.G12V,1,EX2,,,,,,0,,KRAS����������
1355981,Yes,c.530C>G:p.P177R,2,2,1,EX5,0,0,"p.E746_S752delinsV,p.R252C","p.E746_S752delinsV,p.R252C",1.0,"EX19,EX7",0.0,0.0,,,,,,0,,,,,,,0,,
1376196,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1375385,Yes,c.465_486delCCGCGTCCGCGCCATGGCCATC:p.R156Tfs*7,1,1,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1375115,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1365515,No,,,0,0,,,,p.L747_S752delinsQ,p.L747_S752delinsQ,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1367457,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1375883,No,,,0,0,,,,p.D770_N771insSVD,p.D770_N771insSVD,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1374491,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1375525,Yes,c.983_993+5delTCACCCTTCAGGTACT:.,2,2,1,EX9-IVS9,EX9-IVS9,4,,,0.0,,,,4.8 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1377906,Yes,c.747G>T:p.R249S,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1373233,Yes,c.477delC:p.M160Wfs*10,1,1,1,EX5,0,0,p.D770_N771insSVD,p.D770_N771insSVD,1.0,EX20,1.0,1.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1372826,No,,,0,0,,,,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,0.96 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,p.E1433K,1,EX29,
1372618,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1375660,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1371877,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,EML4-ALK�ںϣ�V1��,1,EX13��EX20,
1376235,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1369691,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1373296,Yes,"c.743G>A:p.R248Q,c.722_723delCC:p.S241Lfs*22",2,2,1,"EX7,EX7","2,2",2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1372476,Yes,c.745A>G:p.R249G,2,2,1,EX7,2,2,,,0.0,,,,14.4Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1373645,Yes,c.811G>T:p.E271*,1,1,1,EX8,3,3,p.S752_I759del,p.S752_I759del,1.0,EX19,0.0,0.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1374007,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1367192,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1371754,Yes,c.722_723delCC:p.S241Lfs*22,1,1,1,EX7,2,2,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1297842,No,,,0,0,,,,p.L858R,p.L858R,1.0,,,,,,,,,0,,,,,,,0,,
1370019,No,,,0,0,,,,p.L858R,p.L858R,1.0,,,,,,,,,0,,,,,,,0,,
1372543,Yes,c.548C>G:p.S183*,1,1,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1370585,Yes,c.722C>T:p.S241F,2,2,1,EX7,2,2,,,0.0,,,,15.36Muts/Mb��TMB-H,1.0,,1.0,,0,,p.V600E,EX15,,,,0,,
1371128,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1364457,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1369861,No,,,0,0,,,,,,0.0,,,,30.72Muts/Mb��TMB-H,1.0,,1.0,p.G13C,1,EX2,,,,,,0,,
1370010,No,,,0,0,,,,,,0.0,,,,,,,,p.G12A,1,EX2,,,p.R1022Q,EX15,,0,,
1368220,No,,,0,0,,,,,,0.0,,,,,,,,,0,,p.L597R,EX15,.,IVS14,,0,,
1369586,Yes,c.722C>T:p.S241F,2,2,1,,,,,,0.0,,,,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1371276,Yes,c.542delG:p.R181Pfs*66,1,1,1,EX5,0,0,,,0.0,,,,11.52Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1368142,Yes,c.659A>G:p.Y220C,2,2,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1369786,Yes,c.838A>G:p.R280G,2,2,1,EX8,3,3,,,0.0,,,,9.6Muts/Mb��TMB-H,1.0,,1.0,p.G12A,1,EX2,,,,,,0,,
1372031,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1368504,Yes,c.403delT:p.C135Afs*35,1,1,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1368789,No,,,0,0,,,,p.T790M:p.L858R,p.T790M:p.L858R,1.0,EX20:EX21,1.0,1.0,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1366555,No,,,0,0,,,,p.D770_N771insSVD,p.D770_N771insSVD,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1365356,Yes,c.451C>A:p.P151T,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1369584,Yes,c.743G>T:p.R248L,2,2,1,EX7,2,2,p.Y74F,p.Y74F,1.0,EX2,,,12.48Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,p.P1469L,1,EX29,
1367074,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,p.G12A,1,EX2,,,,,,0,,
1366257,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1366318,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1364441,No,,,0,0,,,,p.L858R:p.S811F,p.L858R:p.S811F,1.0,EX20,1.0,1.0,,,,,,0,,,,,,,0,,
1365360,Yes,c.97-2A>T:.,1,1,1,IVS3,IVS3,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1364256,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1365640,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1346687,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,p.V600E,EX15,,,,0,,
1285881,No,,,0,0,,,,p.H773_V774insAH,p.H773_V774insAH,1.0,EX20,1.0,1.0,,,,,,0,,,,,,p.R1212H,1,EX23,
1366186,No,,,0,0,,,,p.R836C,p.R836C,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1365567,Yes,c.707A>G:p.Y236C;c.920-1G>A:0,2,2,1,EX7;IVS8,2;IVS8,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1365028,Yes,c.673-8_676delTCTCCTAGGTTG:0,1,1,1,IVS6-EX7,IVS6-2,4,,,0.0,,,,6.72Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1251056,Yes,c.538G>T:p.E180*;c.613T>G:p.Y205D,2,2,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,5.76Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1361998,Yes,c.742C>T:p.R248W,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1358509,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1359389,Yes,c.527G>T:p.C176F,2,2,1,EX5,0,0,p.L861Q,p.L861Q,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1351608,No,,,0,0,,,,p.L747_A750delinsP,p.L747_A750delinsP,1.0,EX19,0.0,0.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1364241,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1365182,Yes,c.672+1G>T:.,1,1,1,IVS6,IVS6,4,,,0.0,,,,15.36Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,p.E1077Q,1,EX20,
1364695,Yes,c.746G>T:p.R249M,2,2,1,EX7,2,2,,,0.0,,,,18.24Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1366226,Yes,c.460_461delGGinsAT:p.G154I,2,2,1,EX5,0,0,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1324552,Yes,c.991C>T:p.Q331*,1,1,1,EX9,EX9,4,,,0.0,,,,4.8Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,NM_019063.3:NM_004304.4,1,�ں�V3 EX6:EX20,
1363023,Yes,c.404G>A:p.C135Y,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,NM_019063.3:NM_004304.4,1,�ں�V3 EX6:EX20,
1317534,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,NM_019063.3:NM_004304.4,1,�ں�V3 EX6:EX20,
1361795,Yes,c.817C>A:p.R273S,2,2,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1361668,No,,,0,0,,,,p.L747_K754delinsSR,p.L747_K754delinsSR,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1362278,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1362945,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1360657,No,,,0,0,,,,,,0.0,,,,"0.0Muts/Mb,TMB-L",0.0,0.0,,,0,,,,,,,0,,
1361203,Yes,c.711G>T:p.M237I,2,2,1,EX7,2,2,,,0.0,,,,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1359404,No,,,0,0,,,,p.E746_T751delinsl,p.E746_T751delinsl,1.0,EX19,0.0,0.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1360279,Yes,c.526T>A:p.C176S,2,2,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,4.8Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1359693,Yes,c.815T>A:p.V272E,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,5.76Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1361105,Yes,c.559+1G>A:.,1,1,1,IVS5,IVS5,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1352077,Yes,c.1025delG:p.R342Qfs*3,1,1,1,EX10,EX10,4,,,0.0,,,,4.8Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1356821,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1357310,Yes,c.430C>T:p.Q144*,1,1,1,,,,,,0.0,,,,39.88��ͻ��/Mb,1.0,,1.0,,0,,p.K601E,,,,,0,,
1356923,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1357340,Yes,c.626_627delGA:p.R209Kfs*6,1,1,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,EGFR����
1358599,Yes,c.469G>T:p.V157F,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1358093,Yes,c.128delT:p.L43*fs*1,1,1,1,EX4,EX4,4,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1358198,Yes,c.91G>A:p.V31I;p.722C>G:p.S241C,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1285271,No,,,0,0,,,,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1355101,Yes,c.817C>T:p.R273C,2,2,1,EX8,3,3,p.V769_D770insASV,p.V769_D770insASV,1.0,EX20,1.0,1.0,,,,,,0,,,,.,IVS6,,0,,
1358234,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1353158,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1359393,Yes,c.848G>C:p.R283P,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,p.K1525E,1,EX29,
1358607,Yes,c.870delCinsAATCTCCGT:p.K291Ifs*57,1,1,1,EX8,3,3,p.L858R:p.L62R,p.L858R:p.L62R,1.0,EX21:EX2,2.0,2.0,,,,,,0,,,,,,,0,,
1337050,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1342070,No,,,0,0,,,,,,0.0,,,,1.92 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1355673,No,,,0,0,,,,,,0.0,,,,,,,,p.G12C,1,EX2,,,,,,0,,
1354253,No,,,0,0,,,,,,0.0,,,,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1355666,No,,,0,0,,,,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,,0.0,0.0,,,0,,,,,,,0,,
1355978,No,,,0,0,,,,,,0.0,,,,4.8Muts/Mb��TMB-L,0.0,0.0,,,0,,p.L597R,EX15,,,,0,,
1350239,No,,,0,0,,,,p.L62R:p.L858R,p.L62R:p.L858R,1.0,EX2:EX21,,,,,,,,0,,,,,,,0,,
1355456,Yes,c.716A>G:p.N239S,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1357115,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,KRAS����
1348823,Yes,"c.469G>T:p.V157F
����ϵ��: 1.925974632310108",2,2,1,EX5,0,0,,,0.0,,,,1.92Muts/Mb��TMB-L,0.0,0.0,,p.G12C,1,EX2,,,,,,0,,KRAS����
1353597,Yes,c.949_950insC:p.Q317Pfs*20,1,1,1,EX9,EX9,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1353434,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1358212,Yes,c.369_371delTTGinsC:p.C124Hfs*24,1,1,1,EX4,EX4,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1356475,Yes,c.997delC:p.R333Vfs*12,1,1,1,EX10,EX10,4,,,0.0,,,,9.6Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1355447,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.88Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1344786,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1357055,Yes,c.488A>G:p.Y163C,2,2,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.96Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����
1355191,Yes,c.625A>T:p.R209*,1,1,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1355773,Yes,c.495_498delGTCA:p.Q165Hfs*4,1,1,1,EX5,0,0,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1353460,Yes,c.488A>G:p.Y163C,2,2,1,EX5,0,0,,,0.0,,,,10.56Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1355966,Yes,c.583A>T:p.I195F,2,2,1,EX6,1,1,,,0.0,,,,3.84Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1349497,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1336879,Yes,c.994-1G>T:.,2,2,1,IVS9,IVS9,4,p.L747_T751delinsP,p.L747_T751delinsP,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1355568,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1354529,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,p.G12D,1,EX2,,,,,,0,,
1350519,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1353328,No,,,0,0,,,,,,0.0,,,,,,,,p.G12C,11,EX2,,,,,,0,,
1355338,Yes,c.517G>T:p.V173L,2,2,1,EX5,0,0,,,0.0,,,,"3.84Muts/Mb,TMB-L",0.0,0.0,,,0,,,,,,,0,,
1353589,Yes,c.461G>T:p.G154V,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1350392,Yes,c.376-1G>T:.,2,2,1,IVS4,IVS4,4,,,0.0,,,,,,,,,0,,,,,,,0,,
1344009,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1347382,Yes,c.524G>A:p.R175H,2,2,1,EX5,0,0,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1348751,No,,,0,0,,,,,,0.0,,,,,,,,p.G12A,1,EX2,,,,,,0,,
1351244,Yes,c.818G>C:p.R273P,2,2,1,EX8,3,3,,,0.0,,,,9.6 Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1352016,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1348804,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1348647,Yes,c.821T>G:p.V274G,2,2,1,EX8,3,3,,,0.0,,,,4.8Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1342432,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,NM_019063.3:NM_004304.4,1,�ںϷ�V1V3 EX20:EX20,
1347768,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1348789,Yes,c.475G>C:p.A159P,2,2,1,EX5,0,0,,,0.0,,,,25.92Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1342412,Yes,c.610G>T:p.E204*,1,1,1,EX6,1,1,,,0.0,,,,,,,,,0,,,,,,p.P336Q,1,EX4,EGFR����
1347741,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1349548,Yes,c.641A>G:p.H214R,2,2,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1346674,Yes,c.466delC:p.R156Afs*14,1,1,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,2.88 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,EGFR����;KRAS����;MET����
1347509,Yes,c.843C>G:p.D281E,2,2,1,EX8,3,3,,,0.0,,,,14.4Muts/Mb��TMB-H,1.0,,1.0,,0,,,,p.P839H,EX11,,0,,NRAS����
1347498,No,,,0,0,,,,p.G719A:p.V689L,p.G719A:p.V689L,1.0,EX18:EX18,,,,,,,,0,,,,,,,0,,
1343593,Yes,c.790delC:p.L264Yfs*81,1,1,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1343527,No,,,0,0,,,,,,0.0,,,,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,NM_019063.3:NM_004304.4,1,�ں�V3 EX6:EX20,
1345479,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,NM_019063.3:NM_004304.4,1,�ں�V3 EX6:EX20,
1345899,Yes,c.743G>T:p.R248L,2,2,1,EX7,2,2,,,0.0,,,,15.36Muts/Mb��TMB-H,1.0,,1.0,p.G12A,1,EX2,,,,,,0,,
1328837,No,,,0,0,,,,,,0.0,,,,,,,,p.G12C,1,,,,,,,0,,
1343462,No,,,0,0,,,,,,0.0,,,,12.48Muts/Mb��TMB-H,1.0,,1.0,,0,,,,,,,0,,
1342024,Yes,c.733G>A:p.G245S,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1335752,Yes,c.583dupA:p.I195Nfs*14,1,1,1,EX6,1,1,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1334416,Yes,c.405C>G:p.C135W,2,2,1,EX5,0,0,p.G719A,p.G719A,1.0,EX18,,,,,,,,0,,,,,,,0,,
1332964,Yes,c.806_808delGCT:p.S269_F270delinsI,2,2,1,EX8,3,3,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1343918,Yes,c.715_723delAACAGTTCC:p.N239_S241del,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1343001,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1340934,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1343437,Yes,c.707A>G:p.Y236C,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1343455,No,,,0,0,,,,,,0.0,,,,0.0 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1342830,Yes,c.752T>A:p.I251N,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1339201,Yes,c.742C>T:p.R248W,2,2,1,EX7,2,2,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,4.8 Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1342028,No,,,0,0,,,,p.T790M:p.E746_A750del,p.T790M:p.E746_A750del,1.0,EX20:EX19,1.0,1.0,0.0Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1339491,Yes,c.733G>A:p.G245S,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1339527,Yes,c.80delC:p.P27Lfs*17,1,1,1,EX3,EX3,4,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1339986,No,,,0,0,,,,,,0.0,,,,"9.6Muts/Mb,TMB-H",1.0,,1.0,p.G12V,1,EX2,,,,,,0,,
1338092,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,1.92Muts/Mb��TMB-L,0.0,0.0,,,0,,,,,,,0,,
1338489,No,,,0,0,,,,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1339470,No,,,0,0,,,,,,0.0,,,,,,,,p.G12A,1,EX2,,,,,,0,,
1338103,Yes,c.535C>G:p.H179D,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,p.T895M,EX12,,0,,
1325053,Yes,c.473G>T:p.R158L,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1338080,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,"p.N1335S

NM_019063.3;NM_004304.4",1,"EX27

�ں�(V1)EX13:EX20",
1334146,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,NM_019063.3;NM_004304.4,1,�ں�(V3)EX6:EX20,
1336736,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1335758,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1337738,Yes,c.581T>G:p.L194R,2,2,1,EX6,1,1,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,EGFR����
1337737,No,,,0,0,,,,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1336704,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,NM_019063.3;NM_004304.4,1,�ں�(V1)EX13:EX20,
1334893,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1335440,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,.,.,IVS17,
1335800,Yes,c.725G>A:p.C242Y,2,2,1,EX7,2,2,,,0.0,,,,,,,,p.G12V,1,EX2,,,,,,0,,
1334505,No,,,0,0,,,,,,0.0,,,,,,,,p.G12V,1,EX2,,,,,,0,,
1327355,No,,,0,0,,,,p.E746_S752delinsV,p.E746_S752delinsV,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1334077,Yes,c.743G>T:p.R248L,2,2,1,EX7,2,2,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1333253,No,,,0,0,,,,p.L747_T751del,p.L747_T751del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1331843,Yes,c.746G>T:p.R249M,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1334751,Yes,c.731G>A:p.G244D,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1332415,Yes,c.920-1G>T:.,2,2,1,IVS8,IVS8,4,,,0.0,,,,,,,,,0,,p.V600E,������600,,,,0,,
1333562,Yes,c.853G>A:p.E285K,2,2,1,EX8,3,3,p.E746_A750del,p.E746_A750del,1.0,EX19,0.0,0.0,,,,,,0,,,,,,,0,,
1331405,No,,,0,0,,,,p.E746_A750del:p.T790M,p.E746_A750del:p.T790M,1.0,EX19:EX20,0.0,0.0,,,,,,0,,,,,,,0,,
1331854,Yes,c.746G>T:p.R249M,2,2,1,EX7,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1323489,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1323605,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1319162,Yes,c.844C>T:p.R282W,2,2,1,EX8,3,3,,,0.0,,,,,,,,,0,,,,,,,0,,
1323978,Yes,c.542G>C:p.R181P,2,2,1,EX5,0,0,,,0.0,,,,,,,,,0,,,,,,,0,,
1221751,Yes,c.716A>G:p.N239S;c.535C>T:p.H179Y,2,2,1,EX7:EX5,2,2,,,0.0,,,,,,,,,0,,,,,,,0,,
1326058,Yes,c.537T>A:p.H179Q,2,2,1,EX5,0,0,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1317756,No,,,0,0,,,,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,13.65Muts/Mb (��),1.0,,1.0,,0,,,,,,,0,,
1322801,Yes,c.673-2A>G:.,1,1,1,IVS6,IVS6,4,p.L858R:p.K8601,p.L858R:p.K8601,1.0,EX21:EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1322725,Yes,c.473G>C:p.R158P,2,2,1,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1323345,Yes,c.577delC:p.H193Ifs*54,1,1,1,EX6,1,1,,,0.0,,,,,,,,,0,,,,,,,0,,
1320383,Yes,c.854A>G:p.E285G;c.638G>A:p.R213Q,2,2,1,EX8:EX6,3,3,p.L747_P753delinsS,p.L747_P753delinsS,1.0,EX19,0.0,0.0,3.84Muts/Mb(TMB-L),0.0,0.0,,,0,,,,,,,0,,
1318556,No,,,0,0,,,,p.L858R:p.A289T,p.L858R:p.A289T,1.0,EX21;EX7,2.0,2.0,5.76Muts/Mb(TMB-L),0.0,0.0,,,0,,,,,,,0,,
1320955,No,,,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,
1206273,No,,,0,0,,,,,,0.0,,,,,,,,,0,,,,,,,0,,
1317488,Yes,c.817C>T:p.R273C,2,2,1,EX8,3,3,,,0.0,,,,,,,,p.Q61K,1,EX3,,,,,,0,,
1314798,Yes,"c.637C>T:p.R213*
����ϵ��: 3481.11942326389",1,1,1,EX6,1,1,,,0.0,,,,,,,,p.G12D,1,EX2,,,,,,0,,
1317299,Yes,����ϵ��: 4786.674173989472(��),0,0,0,,,,p.L858R,p.L858R,1.0,EX21,2.0,2.0,,,,,,0,,,,,,,0,,