Datasets:
File size: 3,649 Bytes
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"source": "LiteFold/HumanProteinAtlas",
"entry_rows": 20162,
"cancer_prognostic_rows": 442504,
"rna_expression_measurement_rows": 149150,
"splits": {
"train": 18138,
"test": 2024
},
"split_strategy": "deterministic sha256(ensembl_id) % 10; bucket 0 is test, buckets 1-9 are train",
"evidence_counts": {
"Evidence at protein level": 18564,
"Evidence at transcript level": 1344,
"No human protein/transcript evidence": 254
},
"rna_tissue_specificity_counts": {
"Low tissue specificity": 8096,
"Tissue enhanced": 6356,
"Tissue enriched": 3132,
"Group enriched": 1547,
"Not detected": 1031
},
"top_subcellular_main_locations": {
"Nucleoplasm": 4897,
"Cytosol": 3087,
"Vesicles": 1661,
"Plasma membrane": 1648,
"Mitochondria": 974,
"Golgi apparatus": 886,
"Nucleoli": 638,
"Endoplasmic reticulum": 486,
"Nuclear speckles": 412,
"Nuclear bodies": 326,
"Centrosome": 248,
"Microtubules": 237,
"Nucleoli fibrillar center": 193,
"Nuclear membrane": 193,
"Cell Junctions": 192,
"Mid piece": 151,
"Principal piece": 140,
"Primary cilium": 140,
"Basal body": 139,
"Actin filaments": 138
},
"top_protein_classes": {
"Predicted intracellular proteins": 15915,
"Predicted membrane proteins": 5573,
"Disease related genes": 4906,
"Human disease related genes": 4555,
"Enzymes": 3777,
"Plasma proteins": 3750,
"Metabolic proteins": 2882,
"Transporters": 2138,
"Essential proteins": 2023,
"Predicted secreted proteins": 1902,
"Potential drug targets": 1757,
"Cancer-related genes": 1672,
"Transcription factors": 1485,
"FDA approved drug targets": 854,
"G-protein coupled receptors": 743,
"CD markers": 384,
"RAS pathway related proteins": 235,
"Immunoglobulin genes": 214,
"T-cell receptor genes": 196,
"Ribosomal proteins": 180
},
"columns": [
"ensembl_id",
"gene",
"gene_description",
"uniprot",
"chromosome",
"position",
"evidence",
"hpa_evidence",
"uniprot_evidence",
"nextprot_evidence",
"antibodies",
"gene_synonyms",
"protein_classes",
"biological_processes",
"molecular_functions",
"disease_involvement",
"subcellular_main_locations",
"subcellular_additional_locations",
"secretome_locations",
"secretome_functions",
"reliability_if",
"reliability_ih",
"reliability_mouse_brain",
"interactions",
"ccd_protein",
"ccd_transcript",
"blood_expression_cluster",
"brain_expression_cluster",
"cell_line_expression_cluster",
"single_cell_expression_cluster",
"tissue_expression_cluster",
"rna_tissue_specificity",
"rna_tissue_distribution",
"rna_tissue_specificity_score",
"rna_cell_line_specificity",
"rna_cell_line_distribution",
"rna_cell_line_specificity_score",
"rna_cancer_specificity",
"rna_cancer_distribution",
"rna_cancer_specificity_score",
"rna_single_cell_type_specificity",
"rna_single_cell_type_distribution",
"rna_single_cell_type_specificity_score",
"rna_blood_cell_specificity",
"rna_blood_cell_distribution",
"rna_blood_cell_specificity_score",
"prognostic_cancer_count",
"validated_prognostic_cancer_count",
"potential_prognostic_cancer_count",
"favorable_prognostic_cancers",
"unfavorable_prognostic_cancers",
"prognostic_cancers",
"source_row_index",
"split_bucket"
],
"metadata_tables": [
"metadata/cancer_prognostics.parquet",
"metadata/rna_expression_measurements.parquet"
]
}
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