{
  "source": "LiteFold/HumanProteinAtlas",
  "entry_rows": 20162,
  "cancer_prognostic_rows": 442504,
  "rna_expression_measurement_rows": 149150,
  "splits": {
    "train": 18138,
    "test": 2024
  },
  "split_strategy": "deterministic sha256(ensembl_id) % 10; bucket 0 is test, buckets 1-9 are train",
  "evidence_counts": {
    "Evidence at protein level": 18564,
    "Evidence at transcript level": 1344,
    "No human protein/transcript evidence": 254
  },
  "rna_tissue_specificity_counts": {
    "Low tissue specificity": 8096,
    "Tissue enhanced": 6356,
    "Tissue enriched": 3132,
    "Group enriched": 1547,
    "Not detected": 1031
  },
  "top_subcellular_main_locations": {
    "Nucleoplasm": 4897,
    "Cytosol": 3087,
    "Vesicles": 1661,
    "Plasma membrane": 1648,
    "Mitochondria": 974,
    "Golgi apparatus": 886,
    "Nucleoli": 638,
    "Endoplasmic reticulum": 486,
    "Nuclear speckles": 412,
    "Nuclear bodies": 326,
    "Centrosome": 248,
    "Microtubules": 237,
    "Nucleoli fibrillar center": 193,
    "Nuclear membrane": 193,
    "Cell Junctions": 192,
    "Mid piece": 151,
    "Principal piece": 140,
    "Primary cilium": 140,
    "Basal body": 139,
    "Actin filaments": 138
  },
  "top_protein_classes": {
    "Predicted intracellular proteins": 15915,
    "Predicted membrane proteins": 5573,
    "Disease related genes": 4906,
    "Human disease related genes": 4555,
    "Enzymes": 3777,
    "Plasma proteins": 3750,
    "Metabolic proteins": 2882,
    "Transporters": 2138,
    "Essential proteins": 2023,
    "Predicted secreted proteins": 1902,
    "Potential drug targets": 1757,
    "Cancer-related genes": 1672,
    "Transcription factors": 1485,
    "FDA approved drug targets": 854,
    "G-protein coupled receptors": 743,
    "CD markers": 384,
    "RAS pathway related proteins": 235,
    "Immunoglobulin genes": 214,
    "T-cell receptor genes": 196,
    "Ribosomal proteins": 180
  },
  "columns": [
    "ensembl_id",
    "gene",
    "gene_description",
    "uniprot",
    "chromosome",
    "position",
    "evidence",
    "hpa_evidence",
    "uniprot_evidence",
    "nextprot_evidence",
    "antibodies",
    "gene_synonyms",
    "protein_classes",
    "biological_processes",
    "molecular_functions",
    "disease_involvement",
    "subcellular_main_locations",
    "subcellular_additional_locations",
    "secretome_locations",
    "secretome_functions",
    "reliability_if",
    "reliability_ih",
    "reliability_mouse_brain",
    "interactions",
    "ccd_protein",
    "ccd_transcript",
    "blood_expression_cluster",
    "brain_expression_cluster",
    "cell_line_expression_cluster",
    "single_cell_expression_cluster",
    "tissue_expression_cluster",
    "rna_tissue_specificity",
    "rna_tissue_distribution",
    "rna_tissue_specificity_score",
    "rna_cell_line_specificity",
    "rna_cell_line_distribution",
    "rna_cell_line_specificity_score",
    "rna_cancer_specificity",
    "rna_cancer_distribution",
    "rna_cancer_specificity_score",
    "rna_single_cell_type_specificity",
    "rna_single_cell_type_distribution",
    "rna_single_cell_type_specificity_score",
    "rna_blood_cell_specificity",
    "rna_blood_cell_distribution",
    "rna_blood_cell_specificity_score",
    "prognostic_cancer_count",
    "validated_prognostic_cancer_count",
    "potential_prognostic_cancer_count",
    "favorable_prognostic_cancers",
    "unfavorable_prognostic_cancers",
    "prognostic_cancers",
    "source_row_index",
    "split_bucket"
  ],
  "metadata_tables": [
    "metadata/cancer_prognostics.parquet",
    "metadata/rna_expression_measurements.parquet"
  ]
}