ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000113262 | GRM6 | Glutamate metabotropic receptor 6 | [
"O15303"
] | 5 | 178977587-178996206 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014511"
] | [
"CSNB1B",
"GPRC1F",
"mGlu6",
"MGLUR6"
] | [
"Disease related genes",
"G-protein coupled receptors",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Sensory transduction",
"Vision"
] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"Congenital stationary night blindness",
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in single | 118 | Cancer enriched | Detected in single | 10 | Not detected | Not detected | null | Cell type enriched | Detected in some | 35 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,114 | 6 |
ENSG00000113263 | ITK | IL2 inducible T cell kinase | [
"Q08881"
] | 5 | 157142933-157255185 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA060674"
] | [
"EMT",
"LYK",
"PSCTK2"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Adaptive immunity",
"Immunity"
] | [
"Kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Supported | null | null | 26 | null | null | Cluster 39: T-cells - T-cell receptor | null | Cluster 59: Leukemia - T-cell receptor | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enriched | Detected in some | 13 | Group enriched | Detected in some | 23 | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 22 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 4,115 | 6 |
ENSG00000113269 | RNF130 | Ring finger protein 130 | [
"Q86XS8"
] | 5 | 179911651-180072113 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014499"
] | [
"G1RZFP",
"GOLIATH",
"GP"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Apoptosis",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [] | [] | [] | [] | null | Approved | null | 9 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 30: White matter - Myelination | Cluster 49: HMC-1 - Innate immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Group enriched | Detected in all | 8 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,116 | 7 |
ENSG00000113273 | ARSB | Arylsulfatase B | [
"P15848"
] | 5 | 78777209-78986087 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037770",
"HPA037771"
] | [
"ASB"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [
"Disease variant",
"Ichthyosis",
"Leukodystrophy",
"Metachromatic leukodystrophy",
"Mucopolysaccharidosis"
] | [
"Golgi apparatus"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Approved | Approved | null | 3 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 20: Macrophages & Microglia - Immune response | Cluster 64: Connective tissue cells - ECM organization | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 72: Kidney - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma",
"Thyroid Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Thyroid Carcinoma"
] | 4,118 | 1 |
ENSG00000113282 | CLINT1 | Clathrin interactor 1 | [
"Q14677"
] | 5 | 157785743-157859145 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043280",
"HPA056947"
] | [
"CLINT",
"ENTH",
"EPNR",
"KIAA0171"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Endocytosis"
] | [] | [] | [
"Vesicles"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Supported | null | 52 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 23: Choroid plexus - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enriched | Detected in all | 4 | 4 | 0 | 4 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 4,119 | 9 |
ENSG00000113300 | CNOT6 | CCR4-NOT transcription complex subunit 6 | [
"Q9ULM6"
] | 5 | 180494379-180578358 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044568"
] | [
"CCR4",
"Ccr4a",
"KIAA1194"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"RNA-mediated gene silencing",
"Transcription",
"Transcription regulation",
"Translation regulation"
] | [
"Activator",
"Exonuclease",
"Hydrolase",
"Nuclease",
"RNA-binding"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 46 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 16: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,121 | 5 |
ENSG00000113302 | IL12B | Interleukin 12B | [
"P29460"
] | 5 | 159314780-159330863 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040970"
] | [
"CLMF",
"CLMF2",
"IL-12B",
"NKSF",
"NKSF2"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Cytokine"
] | [
"FDA approved drug targets"
] | [] | [] | [
"Secreted to blood"
] | [
"Interleukin"
] | null | Supported | null | 4 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 82: Dendritic cells - Antigen presentation | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in single | null | Cancer enriched | Detected in single | 13 | Cancer enriched | Detected in some | 5 | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,122 | 7 |
ENSG00000113303 | BTNL8 | Butyrophilin like 8 | [
"Q6UX41"
] | 5 | 180899077-180950906 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039738"
] | [
"BTN9.2",
"FLJ21458"
] | [
"Predicted membrane proteins"
] | [
"Adaptive immunity",
"Immunity"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 1 | null | null | Cluster 21: Neutrophils - Unknown function | null | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 7: Small intestine - Absorption and Digestion | Tissue enriched | Detected in some | 16 | Group enriched | Detected in some | 5 | Group enriched | Detected in some | 12 | Group enriched | Detected in some | 4 | Immune cell enriched | Detected in some | 12 | 0 | 0 | 0 | [] | [] | [] | 4,123 | 2 |
ENSG00000113312 | TTC1 | Tetratricopeptide repeat domain 1 | [
"Q99614"
] | 5 | 160009113-160065543 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036557",
"HPA057502"
] | [
"TPR1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 38 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 45: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,124 | 4 |
ENSG00000113318 | MSH3 | MutS homolog 3 | [
"P20585"
] | 5 | 80654652-80876815 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036081"
] | [
"DUP",
"MRP1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"DNA-binding"
] | [] | [
"Nuclear bodies"
] | [] | [] | [] | Approved | null | null | 23 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 7: Non-specific - Ribosome | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,125 | 2 |
ENSG00000113319 | RASGRF2 | Ras protein specific guanine nucleotide releasing factor 2 | [
"O14827"
] | 5 | 80960363-81230162 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018679"
] | [
"GRF2",
"Ras-GRF2"
] | [
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [] | [
"Calmodulin-binding",
"Guanine-nucleotide releasing factor"
] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Uncertain | null | null | null | null | Cluster 27: T-cells - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,126 | 5 |
ENSG00000113327 | GABRG2 | Gamma-aminobutyric acid type A receptor subunit gamma2 | [
"P18507"
] | 5 | 162000057-162162977 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB079060"
] | [] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Chloride channel",
"Ion channel"
] | [
"Disease variant",
"Epilepsy",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | null | Supported | 3 | null | null | Cluster 32: Basophils - Transcription | Cluster 53: Neurons - Mixed function | Cluster 56: Non-specific - Sensory perception | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 10: Brain - Synaptic signal transduction | Group enriched | Detected in some | 6 | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 4,127 | 7 |
ENSG00000113328 | CCNG1 | Cyclin G1 | [
"P51959"
] | 5 | 163437569-163446151 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000350"
] | [
"CCNG"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [
"Cyclin"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 22 | null | null | Cluster 31: T-cells - T-cell receptor | Cluster 50: Non-specific - Nucleic acid binding | Cluster 25: Non-specific - Ribosome | Cluster 47: Platelets - Hemostasis | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 4,128 | 3 |
ENSG00000113356 | POLR3G | RNA polymerase III subunit G | [
"O15318"
] | 5 | 90471748-90514557 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010109",
"HPA052658",
"HPA074330"
] | [
"C31",
"RPC32",
"RPC7"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"RNA polymerase related proteins"
] | [
"Antiviral defense",
"Immunity",
"Innate immunity",
"Transcription"
] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 55 | null | null | Cluster 32: Basophils - Transcription | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 72: Neuronal - Signal transduction | Cluster 109: Neurons - Neuronal signaling | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 6 | 0 | 6 | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,129 | 5 |
ENSG00000113360 | DROSHA | Drosha ribonuclease III | [
"Q9NRR4"
] | 5 | 31400494-31532196 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031150"
] | [
"Etohi2",
"HSA242976",
"RN3",
"RNASE3L",
"RNASEN"
] | [
"Cancer-related genes",
"Enzymes",
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis",
"RNA-mediated gene silencing"
] | [
"Endonuclease",
"Hydrolase",
"Nuclease",
"RNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 26 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 29: Non-specific - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 4,130 | 6 |
ENSG00000113361 | CDH6 | Cadherin 6 | [
"P55285"
] | 5 | 31193686-31329146 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007047",
"HPA007403",
"HPA007456",
"CAB025274"
] | [] | [
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Plasma membrane",
"Cell Junctions"
] | [] | [] | [] | Supported | Enhanced | null | 1 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 7 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 4,131 | 4 |
ENSG00000113368 | LMNB1 | Lamin B1 | [
"P20700"
] | 5 | 126776623-126837020 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005269",
"HPA050524",
"CAB079757",
"CAB079954"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant",
"Intellectual disability",
"Leukodystrophy",
"Primary microcephaly"
] | [
"Nuclear membrane"
] | [] | [] | [] | Supported | Supported | null | 190 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 80: Thymus - Adaptive immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 4,132 | 3 |
ENSG00000113384 | GOLPH3 | Golgi phosphoprotein 3 | [
"Q9H4A6"
] | 5 | 32124716-32174319 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044564",
"HPA055841"
] | [
"GOPP1",
"GPP34",
"MIDAS",
"Vps74"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Golgi apparatus",
"Vesicles"
] | [] | [] | [] | Supported | Approved | null | 42 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 29: Non-specific - Unknown function | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 45: Liver - Metabolism & Coagulation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 4,134 | 6 |
ENSG00000113387 | SUB1 | SUB1 regulator of transcription | [
"P53999"
] | 5 | 32531633-32604079 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001311",
"CAB015351"
] | [
"p14",
"p15",
"PC4"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | [] | Supported | Supported | null | 58 | null | null | Cluster 32: Basophils - Transcription | Cluster 14: Neurons - Synaptic function | Cluster 51: Myeloma - Immunoglobulins | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,135 | 8 |
ENSG00000113396 | SLC27A6 | Solute carrier family 27 member 6 | [
"Q9Y2P4"
] | 5 | 128538013-129033642 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA008987"
] | [
"ACSVL2",
"FACVL2",
"FATP6",
"VLCS-H1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Fatty acid metabolism",
"Lipid metabolism",
"Lipid transport",
"Transport"
] | [
"Ligase"
] | [] | [
"Nuclear bodies"
] | [] | [] | [] | Approved | Approved | null | 13 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 3: Rhabdoid - Membrane components | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 35: Non-specific - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 9 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Breast Invasive Carcinoma"
] | [] | [
"Breast Invasive Carcinoma"
] | 4,138 | 2 |
ENSG00000113407 | TARS1 | Threonyl-tRNA synthetase 1 | [
"P26639"
] | 5 | 33440696-33468091 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA037425"
] | [
"TARS"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Aminoacyl-tRNA synthetase",
"Ligase",
"RNA-binding",
"tRNA-binding"
] | [
"Disease variant"
] | [
"Cytosol"
] | [
"Actin filaments"
] | [] | [] | Approved | Approved | null | 16 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 26: Oligodendrocytes - Mixed function | Cluster 29: Non-specific - Unknown function | Cluster 17: Non-specific - RNA processing | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,139 | 6 |
ENSG00000113430 | IRX4 | Iroquois homeobox 4 | [
"P78413"
] | 5 | 1877413-1887236 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA064094"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Uncertain | null | null | 3 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 26: Keratinocytes - Keratinization | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,140 | 8 |
ENSG00000113441 | LNPEP | Leucyl and cystinyl aminopeptidase | [
"Q9UIQ6"
] | 5 | 96935394-97037513 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043642"
] | [
"CAP",
"IRAP",
"P-LAP",
"PLAP"
] | [
"Enzymes",
"Predicted membrane proteins"
] | [] | [
"Aminopeptidase",
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Approved | null | 28 | null | null | Cluster 32: Basophils - Transcription | Cluster 25: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,141 | 3 |
ENSG00000113448 | PDE4D | Phosphodiesterase 4D | [
"Q08499"
] | 5 | 58969038-60522120 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045895"
] | [
"DPDE3"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Plasma membrane",
"Cytosol"
] | [
"Nucleoplasm",
"Nuclear membrane",
"Primary cilium"
] | [] | [] | Approved | Uncertain | null | 19 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 7: Liver cancer - Metabolism | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enriched | Detected in many | 5 | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 4,142 | 8 |
ENSG00000113456 | RAD1 | RAD1 checkpoint DNA exonuclease | [
"O60671"
] | 5 | 34905260-34918989 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA006692"
] | [
"HRAD1",
"REC1"
] | [
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [] | [] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 28 | null | Yes | Cluster 3: Non-specific - Nuclear processes | Cluster 31: Non-specific - Transcription | Cluster 29: Non-specific - Unknown function | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enriched | Detected in all | 4 | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,143 | 3 |
ENSG00000113460 | BRIX1 | Biogenesis of ribosomes BRX1 | [
"Q8TDN6"
] | 5 | 34915677-34925996 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039614"
] | [
"BRIX",
"BXDC2",
"FLJ11100"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis"
] | [] | [] | [
"Nucleoli",
"Mitotic chromosome"
] | [] | [] | [] | Enhanced | null | null | 90 | Yes | No | Cluster 3: Non-specific - Nuclear processes | Cluster 28: Oligodendrocytes - Mixed function | Cluster 29: Non-specific - Unknown function | Cluster 17: Non-specific - RNA processing | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,144 | 5 |
ENSG00000113492 | AGXT2 | Alanine--glyoxylate aminotransferase 2 | [
"Q9BYV1"
] | 5 | 34998101-35048135 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037382"
] | [
"AGT2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Aminotransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | null | Cluster 18: Liver cancer - Metabolism | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 76: Non-specific - Metabolism | Group enriched | Detected in some | 43 | Not detected | Not detected | null | Group enriched | Detected in some | 114 | Group enriched | Detected in some | 12 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,145 | 2 |
ENSG00000113494 | PRLR | Prolactin receptor | [
"P16471"
] | 5 | 35048756-35230487 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Receptor"
] | null | null | null | 8 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 36: Choroid plexus - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 8 | Group enriched | Detected in many | 6 | Cell type enriched | Detected in many | 8 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 4,146 | 7 |
ENSG00000113504 | SLC12A7 | Solute carrier family 12 member 7 | [
"Q9Y666"
] | 5 | 1050384-1112063 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041652"
] | [
"DKFZP434F076",
"KCC4"
] | [
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Potassium transport",
"Symport",
"Transport"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Uncertain | Approved | null | 24 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 42: Choroid plexus - Mitochondria | Cluster 10: Ciliated cells - Ion channel activity | Cluster 22: Non-specific - Basic cellular functions | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,147 | 8 |
ENSG00000113520 | IL4 | Interleukin 4 | [
"P05112"
] | 5 | 132673986-132682678 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA072995",
"CAB078477"
] | [
"BCGF-1",
"BCGF1",
"BSF1",
"IL-4",
"MGC79402"
] | [
"Cancer-related genes",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [
"B-cell activation"
] | [
"Cytokine",
"Growth factor"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [] | [] | [
"Secreted to blood"
] | [
"Interleukin"
] | null | Approved | null | 3 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 50: Lymphoma - Unknown function | Cluster 9: T-cells - Adaptive immunity: Regulation | null | Not detected | Not detected | null | Cancer enhanced | Detected in single | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 862 | 0 | 0 | 0 | [] | [] | [] | 4,148 | 6 |
ENSG00000113522 | RAD50 | RAD50 double strand break repair protein | [
"Q92878"
] | 5 | 132556019-132646349 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022103",
"CAB024979",
"HPA052291",
"CAB080379"
] | [
"hRad50",
"RAD50-2"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"DNA damage",
"DNA repair",
"Host-virus interaction",
"Meiosis"
] | [
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Supported | Supported | null | 69 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 9: Non-specific - Receptor signaling | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 22: Non-specific - Basic cellular functions | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 8 | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 4,149 | 6 |
ENSG00000113525 | IL5 | Interleukin 5 | [
"P05113"
] | 5 | 132541445-132556838 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB010304"
] | [
"EDF",
"IL-5",
"TRF"
] | [
"Cancer-related genes",
"FDA approved drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Cytokine",
"Growth factor"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [] | [] | [
"Secreted to blood"
] | [
"Interleukin"
] | null | Approved | null | 4 | null | null | null | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 59: Leukemia - T-cell receptor | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in single | 6 | Cancer enriched | Detected in single | 4 | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 8 | 0 | 0 | 0 | [] | [] | [] | 4,150 | 3 |
ENSG00000113532 | ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | [
"Q92187"
] | 5 | 100806933-100903282 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036437",
"HPA051126",
"HPA053995"
] | [
"PST",
"PST1",
"SIAT8D"
] | [
"Metabolic proteins",
"Predicted secreted proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [] | [
"Golgi apparatus"
] | [] | [
"Secreted - unknown location"
] | [
"Enzyme"
] | Supported | Approved | null | 3 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 49: Hindbrain - Mixed function | Cluster 21: Lymphoma - Adaptive immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,151 | 7 |
ENSG00000113552 | GNPDA1 | Glucosamine-6-phosphate deaminase 1 | [
"P46926"
] | 5 | 141991749-142013041 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000499",
"HPA046891"
] | [
"GNPDA",
"GNPI",
"GPI",
"HLN",
"KIAA0060"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism"
] | [
"Hydrolase",
"Isomerase"
] | [] | [
"Vesicles"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Uncertain | null | 6 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 21: Non-specific - Metabolism | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 72: Kidney - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,152 | 5 |
ENSG00000113555 | PCDH12 | Protocadherin 12 | [
"Q9NPG4"
] | 5 | 141943581-141969741 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051242"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [
"Disease variant",
"Epilepsy",
"Intellectual disability",
"Primary microcephaly"
] | [] | [] | [
"Secreted to blood"
] | [
"Cell adhesion"
] | null | Uncertain | null | null | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 48: Non-specific - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 8 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 4,153 | 7 |
ENSG00000113558 | SKP1 | S-phase kinase associated protein 1 | [
"P63208"
] | 5 | 134148935-134176964 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB012982",
"HPA053745"
] | [
"EMC19",
"MGC34403",
"OCP-II",
"OCP2",
"p19A",
"SKP1A",
"TCEB1L"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Cytokinetic bridge",
"Primary cilium",
"Centrosome",
"Basal body"
] | [] | [] | Approved | Approved | null | 334 | Yes | No | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 21: Non-specific - Metabolism | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,154 | 8 |
ENSG00000113569 | NUP155 | Nucleoporin 155 | [
"O75694"
] | 5 | 37288137-37371106 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037775"
] | [
"KIAA0791",
"N155"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"mRNA transport",
"Protein transport",
"Translocation",
"Transport"
] | [] | [
"Atrial fibrillation",
"Disease variant"
] | [
"Nuclear membrane"
] | [] | [] | [] | Enhanced | Enhanced | null | 56 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 55: Non-specific - Transcription | Cluster 29: Non-specific - Unknown function | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,155 | 2 |
ENSG00000113575 | PPP2CA | Protein phosphatase 2 catalytic subunit alpha | [
"P67775"
] | 5 | 134194035-134226073 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB003848",
"HPA043236"
] | [
"PP2AC",
"PP2Calpha"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Meiosis"
] | [
"Hydrolase",
"Protein phosphatase"
] | [
"Disease variant",
"Intellectual disability"
] | [] | [] | [] | [] | null | Approved | null | 287 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 34: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 17: Non-specific - RNA processing | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,156 | 2 |
ENSG00000113578 | FGF1 | Fibroblast growth factor 1 | [
"P05230"
] | 5 | 142592178-142698070 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003265",
"CAB017519"
] | [
"AFGF",
"ECGF",
"ECGF-beta",
"ECGFA",
"ECGFB",
"FGF-alpha",
"FGFA",
"GLIO703",
"HBGF1"
] | [
"Cancer-related genes",
"FDA approved drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [
"Angiogenesis",
"Differentiation"
] | [
"Developmental protein",
"Growth factor",
"Heparin-binding",
"Mitogen"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [] | [
"Secreted in other tissues"
] | [
"Growth factor"
] | Supported | Enhanced | null | 28 | null | null | null | Cluster 13: Oligodendrocytes - Mixed function | Cluster 70: DU4475 - Unknown function | Cluster 57: Podocytes - Glomerular filtration | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in many | 5 | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in many | 11 | Group enriched | Detected in many | 5 | Not detected in immune cells | Not detected | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Thyroid Carcinoma"
] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Thyroid Carcinoma"
] | 4,157 | 1 |
ENSG00000113580 | NR3C1 | Nuclear receptor subfamily 3 group C member 1 | [
"P04150"
] | 5 | 143277931-143435512 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004248",
"CAB010435"
] | [
"GR",
"GRL"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Nuclear receptors",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Apoptosis",
"Cell cycle",
"Cell division",
"Chromosome partition",
"Mitosis",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"DNA-binding",
"Receptor",
"RNA-binding"
] | [
"Disease variant",
"FDA approved drug targets",
"Pseudohermaphroditism"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Mitochondria"
] | [] | [] | Supported | Supported | null | 122 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 31: Non-specific - Transcription | Cluster 15: Kidney cancer - Membrane components | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 4,158 | 4 |
ENSG00000113583 | C5orf15 | Chromosome 5 open reading frame 15 | [
"Q8NC54"
] | 5 | 133955510-133968674 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011951",
"HPA039165"
] | [
"HTGN29",
"KCT2"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Uncertain | null | 3 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 50: Non-specific - Nucleic acid binding | Cluster 15: Kidney cancer - Membrane components | Cluster 108: Fibroblasts - ECM organization | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,159 | 7 |
ENSG00000113593 | PPWD1 | Peptidylprolyl isomerase domain and WD repeat containing 1 | [
"Q96BP3"
] | 5 | 65563236-65587549 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019353",
"HPA019360"
] | [
"KIAA0073"
] | [
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Isomerase",
"Rotamase"
] | [] | [
"Nuclear bodies"
] | [] | [] | [] | Supported | Enhanced | null | 13 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 28: Oligodendrocytes - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,160 | 3 |
ENSG00000113594 | LIFR | LIF receptor subunit alpha | [
"P42702"
] | 5 | 38474668-38608354 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB080607",
"CAB080608"
] | [
"CD118"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [
"Cancer-related genes",
"Disease variant"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Receptor"
] | null | Supported | null | 6 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,161 | 2 |
ENSG00000113595 | TRIM23 | Tripartite motif containing 23 | [
"P36406"
] | 5 | 65589690-65625975 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039605"
] | [
"ARD1",
"ARFD1",
"RNF46"
] | [
"Cancer-related genes",
"Enzymes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Immunity",
"Innate immunity",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Approved | null | 174 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 34: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 7: Non-specific - Transcription | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,162 | 4 |
ENSG00000113597 | TRAPPC13 | Trafficking protein particle complex subunit 13 | [
"A5PLN9"
] | 5 | 65625004-65666233 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037777"
] | [
"C5orf44",
"FLJ13611",
"MGC48585"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | [] | Approved | Approved | null | 11 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 27: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 7: Non-specific - Transcription | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 4,163 | 6 |
ENSG00000113600 | C9 | Complement C9 | [
"P02748"
] | 5 | 39284140-39371324 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002151",
"HPA029577"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Complement alternate pathway",
"Complement pathway",
"Cytolysis",
"Immunity",
"Innate immunity"
] | [] | [
"Age-related macular degeneration",
"Disease variant"
] | [] | [] | [
"Secreted to blood"
] | [
"Complement pathway"
] | null | Uncertain | null | 6 | null | null | null | null | Cluster 59: Leukemia - T-cell receptor | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 263 | Not detected | Not detected | null | Cancer enriched | Detected in some | 72 | Cell type enriched | Detected in some | 55 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,164 | 5 |
ENSG00000113621 | TXNDC15 | Thioredoxin domain containing 15 | [
"Q96J42"
] | 5 | 134874371-134901635 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA015483"
] | [
"2310047H23Rik",
"C5orf14",
"FLJ22625"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [
"Ciliopathy",
"Disease variant",
"Meckel syndrome"
] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,166 | 9 |
ENSG00000113638 | TTC33 | Tetratricopeptide repeat domain 33 | [
"Q6PID6"
] | 5 | 40512333-40755963 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038252",
"HPA038253"
] | [
"OSRF"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Golgi apparatus",
"Vesicles"
] | [] | [] | Approved | Approved | null | 39 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 31: Non-specific - Transcription | Cluster 29: Non-specific - Unknown function | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 19: Skeletal muscle - Striated muscle contraction | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,167 | 5 |
ENSG00000113643 | RARS1 | Arginyl-tRNA synthetase 1 | [
"P54136"
] | 5 | 168486451-168519301 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003979",
"HPA004130"
] | [
"DALRD1",
"RARS"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Aminoacyl-tRNA synthetase",
"Ligase"
] | [
"Disease variant",
"Leukodystrophy"
] | [
"Cytosol"
] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | Supported | Approved | null | 36 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 31: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,168 | 1 |
ENSG00000113645 | WWC1 | WW and C2 domain containing 1 | [
"Q8IX03"
] | 5 | 168291645-168472303 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038016",
"HPA038017"
] | [
"KIAA0869",
"KIBRA",
"PPP1R168"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Repressor"
] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Approved | null | 39 | null | null | null | Cluster 44: Non-specific - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 4,169 | 2 |
ENSG00000113649 | TCERG1 | Transcription elongation regulator 1 | [
"O14776"
] | 5 | 146447311-146511961 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064854",
"HPA069752",
"HPA069808"
] | [
"CA150",
"TAF2S",
"Urn1"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 54 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 37: Neurons - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 17: Non-specific - RNA processing | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,171 | 1 |
ENSG00000113657 | DPYSL3 | Dihydropyrimidinase like 3 | [
"Q14195"
] | 5 | 147390808-147510068 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA010948"
] | [
"CRMP4",
"DRP-3",
"ULIP"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 9 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 32: Non-specific - Cell proliferation | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 4,172 | 3 |
ENSG00000113658 | SMAD5 | SMAD family member 5 | [
"Q99717"
] | 5 | 136132845-136188747 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA058931"
] | [
"Dwfc",
"JV5-1",
"MADH5"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 16 | null | null | Cluster 32: Basophils - Transcription | Cluster 25: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Immune cell enhanced | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 4,173 | 3 |
ENSG00000113716 | HMGXB3 | HMG-box containing 3 | [
"Q12766"
] | 5 | 150000046-150053142 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA005967"
] | [
"HMGX3",
"KIAA0194",
"SMF"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"DNA-binding"
] | [] | [
"Nucleoli"
] | [] | [] | [] | Approved | null | null | null | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 36: Choroid plexus - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 7: Non-specific - Transcription | Cluster 69: Parathyroid gland - Mixed function | Tissue enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,175 | 8 |
ENSG00000113719 | ERGIC1 | Endoplasmic reticulum-golgi intermediate compartment 1 | [
"Q969X5"
] | 5 | 172834251-172952792 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018666",
"HPA018900"
] | [
"ERGIC-32",
"ERGIC32",
"KIAA1181",
"NET24"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [
"ER-Golgi transport",
"Transport"
] | [] | [
"Disease variant"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Enhanced | Enhanced | null | 14 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 44: Non-specific - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 4,176 | 9 |
ENSG00000113721 | PDGFRB | Platelet derived growth factor receptor beta | [
"P09619"
] | 5 | 150113839-150155872 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB003842",
"CAB018144",
"HPA028499"
] | [
"CD140b",
"JTK12",
"PDGFR",
"PDGFR1"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"RAS pathway related proteins",
"Transporters"
] | [
"Chemotaxis"
] | [
"Developmental protein",
"Kinase",
"Receptor",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets",
"Proto-oncogene"
] | [
"Vesicles"
] | [
"Golgi apparatus"
] | [] | [] | Supported | Enhanced | null | 61 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 23: Choroid plexus - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 110: Mural cells - ECM organization | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 4,177 | 6 |
ENSG00000113722 | CDX1 | Caudal type homeobox 1 | [
"P47902"
] | 5 | 150166778-150184558 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055196"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 4 | null | null | null | null | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 77: Intestine - Digestion | Tissue enriched | Detected in some | 14 | Group enriched | Detected in some | 7 | Group enriched | Detected in many | 4 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,178 | 2 |
ENSG00000113732 | ATP6V0E1 | ATPase H+ transporting V0 subunit e1 | [
"O15342"
] | 5 | 172983771-173035445 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"ATP6H",
"ATP6V0E",
"M9.2"
] | [
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Hydrogen ion transport",
"Ion transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | null | null | 13 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 21: Non-specific - Metabolism | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,179 | 1 |
ENSG00000113734 | BNIP1 | BCL2 interacting protein 1 | [
"Q12981"
] | 5 | 173144442-173164387 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008009",
"HPA008149"
] | [
"Nip1",
"SEC20"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis",
"ER-Golgi transport",
"Host-virus interaction",
"Transport"
] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Supported | null | 72 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 45: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 41: Oocytes - Oogenesis | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Colon Adenocarcinoma"
] | [] | [
"Colon Adenocarcinoma"
] | 4,180 | 5 |
ENSG00000113739 | STC2 | Stanniocalcin 2 | [
"O76061"
] | 5 | 173314723-173328447 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045372"
] | [
"STC-2"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Hormone"
] | [] | [
"Endoplasmic reticulum"
] | [] | [
"Secreted in other tissues"
] | [
"Hormone"
] | Approved | Approved | null | 2 | null | null | null | Cluster 27: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 55: Breast - Lactation | Tissue enriched | Detected in many | 4 | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in all | 4 | Cell type enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Breast Invasive Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,181 | 4 |
ENSG00000113742 | CPEB4 | Cytoplasmic polyadenylation element binding protein 4 | [
"Q17RY0"
] | 5 | 173888349-173961980 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038394"
] | [
"KIAA1673"
] | [
"Predicted intracellular proteins"
] | [] | [
"RNA-binding"
] | [] | [
"Nucleoplasm",
"Golgi apparatus"
] | [
"Vesicles"
] | [] | [] | Approved | null | null | 4 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 31: Non-specific - Transcription | Cluster 47: Leukemia - Hemostasis | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,182 | 3 |
ENSG00000113758 | DBN1 | Drebrin 1 | [
"Q16643"
] | 5 | 177456608-177474401 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051452",
"HPA056940"
] | [
"D0S117E"
] | [
"Disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Actin-binding",
"Developmental protein"
] | [
"Alzheimer disease",
"Amyloidosis",
"Neurodegeneration"
] | [
"Plasma membrane"
] | [
"Actin filaments"
] | [] | [] | Approved | Enhanced | Supported | 51 | null | null | Cluster 1: T-cells - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 108: Fibroblasts - ECM organization | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 4,184 | 6 |
ENSG00000113761 | ZNF346 | Zinc finger protein 346 | [
"Q9UL40"
] | 5 | 177022696-177081189 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018485"
] | [
"JAZ",
"Zfp346"
] | [
"Predicted intracellular proteins"
] | [] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 33 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 15: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,185 | 7 |
ENSG00000113763 | UNC5A | Unc-5 netrin receptor A | [
"Q6ZN44"
] | 5 | 176810519-176880898 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA071450"
] | [
"KIAA1976",
"UNC5H1"
] | [
"Predicted membrane proteins"
] | [
"Apoptosis"
] | [
"Developmental protein",
"Receptor"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | null | null | 2 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 4,186 | 4 |
ENSG00000113790 | EHHADH | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase | [
"Q08426"
] | 3 | 185190624-185281990 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036401",
"HPA042021"
] | [
"ECHD"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Isomerase",
"Lyase",
"Multifunctional enzyme",
"Oxidoreductase"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 105 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 42: Choroid plexus - Mitochondria | Cluster 15: Kidney cancer - Membrane components | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 16: Liver & Kidney - Metabolism | Group enriched | Detected in all | 11 | Low cancer specificity | Detected in all | null | Group enriched | Detected in all | 5 | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,187 | 3 |
ENSG00000113805 | CNTN3 | Contactin 3 | [
"Q9P232"
] | 3 | 74262568-74614659 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA003341"
] | [
"BIG-1",
"PANG"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell adhesion"
] | [] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Cell adhesion"
] | null | Approved | null | null | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 64: Connective tissue cells - ECM organization | Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 4,188 | 3 |
ENSG00000113811 | SELENOK | Selenoprotein K | [
"Q9Y6D0"
] | 3 | 53884417-53891885 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008196"
] | [
"SELK"
] | [
"Predicted membrane proteins"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 28 | null | null | Cluster 41: Basophils - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 50: Lymphoma - Unknown function | Cluster 103: Non-specific - Basic cellular processes | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in all | 5 | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,190 | 4 |
ENSG00000113812 | ACTR8 | Actin related protein 8 | [
"Q9H981"
] | 3 | 53867066-53882152 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065236"
] | [
"ARP8",
"INO80N"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA damage",
"DNA recombination",
"DNA repair",
"Mitosis",
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm"
] | [
"Centrosome"
] | [] | [] | Supported | null | null | 39 | null | null | Cluster 32: Basophils - Transcription | Cluster 21: Non-specific - Metabolism | Cluster 8: Non-specific - Basic cellular processes | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 4,191 | 4 |
ENSG00000113838 | TBCCD1 | TBCC domain containing 1 | [
"Q9NVR7"
] | 3 | 186546067-186570543 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"FLJ10560"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | 9 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 50: Non-specific - Nucleic acid binding | Cluster 63: Non-specific - Protein processing | Cluster 65: Non-specific - Cell growth & division | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 4,192 | 6 |
ENSG00000113845 | TIMMDC1 | Translocase of inner mitochondrial membrane domain containing 1 | [
"Q9NPL8"
] | 3 | 119498547-119525090 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053214",
"HPA055846"
] | [
"C3orf1",
"FLJ22597"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Chaperone"
] | [
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | Uncertain | null | 111 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 27: Non-specific - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 41: Striated muscle - Muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,193 | 5 |
ENSG00000113851 | CRBN | Cereblon | [
"Q96SW2"
] | 3 | 3144628-3179727 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045910"
] | [
"MRT2",
"MRT2A"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Transporters"
] | [
"Ubl conjugation pathway"
] | [] | [
"Disease variant",
"FDA approved drug targets",
"Intellectual disability"
] | [] | [] | [] | [] | null | Approved | null | 56 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 28: Oligodendrocytes - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 47: Platelets - Hemostasis | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 4,194 | 4 |
ENSG00000113889 | KNG1 | Kininogen 1 | [
"P01042"
] | 3 | 186717348-186744410 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001616",
"HPA001645",
"CAB009809"
] | [
"BDK",
"BK",
"HK",
"HMWK",
"KNG"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Blood coagulation",
"Hemostasis",
"Inflammatory response"
] | [
"Protease inhibitor",
"Thiol protease inhibitor",
"Vasoactive",
"Vasodilator"
] | [
"Disease variant"
] | [] | [] | [
"Secreted to blood"
] | [
"Blood coagulation"
] | null | Enhanced | null | 2 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 16: Liver & Kidney - Metabolism | Tissue enriched | Detected in some | 7 | Group enriched | Detected in some | 11 | Cancer enriched | Detected in some | 21 | Group enriched | Detected in some | 10 | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 4,195 | 8 |
ENSG00000113905 | HRG | Histidine rich glycoprotein | [
"P04196"
] | 3 | 186660216-186678234 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050269",
"HPA054598"
] | [
"HPRG",
"HRGP"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Angiogenesis",
"Blood coagulation",
"Chemotaxis",
"Fibrinolysis",
"Hemostasis"
] | [
"Heparin-binding"
] | [
"Disease variant",
"Thrombophilia"
] | [] | [] | [
"Secreted to blood"
] | [
"Blood coagulation"
] | null | Supported | null | 11 | null | null | null | null | Cluster 18: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 173 | Not detected | Not detected | null | Cancer enriched | Detected in some | 197 | Cell type enriched | Detected in some | 55 | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 4,196 | 9 |
ENSG00000113916 | BCL6 | BCL6 transcription repressor | [
"P41182"
] | 3 | 187721377-187745725 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000307",
"HPA004899",
"HPA050645"
] | [
"BCL5",
"BCL6A",
"LAZ3",
"ZBTB27",
"ZNF51"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Immunity",
"Inflammatory response",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [
"Golgi apparatus"
] | [] | [] | Supported | Enhanced | null | 81 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 25: Non-specific - Transcription | Cluster 46: Lymphoma - Humoral immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 24: Non-specific - Transcription | Tissue enhanced | Detected in all | null | Cancer enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Group enriched | Detected in all | 5 | 0 | 0 | 0 | [] | [] | [] | 4,197 | 5 |
ENSG00000113924 | HGD | Homogentisate 1,2-dioxygenase | [
"Q93099"
] | 3 | 120628172-120682269 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047374",
"HPA052359"
] | [
"AKU",
"HGO"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Phenylalanine catabolism",
"Tyrosine catabolism"
] | [
"Dioxygenase",
"Oxidoreductase"
] | [
"Disease variant"
] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Enhanced | null | 2 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 16: Liver & Kidney - Metabolism | Group enriched | Detected in many | 8 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 6 | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 4,198 | 4 |
ENSG00000113946 | CLDN16 | Claudin 16 | [
"Q9Y5I7"
] | 3 | 190322541-190412138 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA056020"
] | [
"HOMG3",
"PCLN1"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [] | [
"Disease variant",
"Primary hypomagnesemia"
] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 72: Kidney - Transmembrane transport | Tissue enriched | Detected in some | 7 | Group enriched | Detected in many | 10 | Group enriched | Detected in many | 13 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,199 | 6 |
ENSG00000113966 | ARL6 | ADP ribosylation factor like GTPase 6 | [
"Q9H0F7"
] | 3 | 97764521-97801229 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019361"
] | [
"BBS3",
"RP55"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation",
"Protein transport",
"Sensory transduction",
"Transport",
"Vision"
] | [] | [
"Bardet-Biedl syndrome",
"Ciliopathy",
"Disease variant",
"Intellectual disability",
"Obesity",
"Retinitis pigmentosa"
] | [
"Microtubules",
"Primary cilium"
] | [
"Nucleoplasm",
"Primary cilium tip",
"Cytosol"
] | [] | [] | Approved | Approved | null | 5 | null | null | Cluster 24: Non-specific - Transcription | Cluster 14: Neurons - Synaptic function | Cluster 1: Neuronal - Visual perception | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,200 | 9 |
ENSG00000113971 | NPHP3 | Nephrocystin 3 | [
"Q7Z494"
] | 3 | 132680609-132722432 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA009150"
] | [
"CFAP31",
"FLJ30691",
"FLJ36696",
"KIAA2000",
"MKS7",
"NPH3",
"SLSN3"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Wnt signaling pathway"
] | [] | [
"Ciliopathy",
"Disease variant",
"Meckel syndrome",
"Nephronophthisis"
] | [
"Nucleoli",
"Primary cilium"
] | [
"Nucleoplasm",
"Vesicles",
"Primary cilium tip",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 8 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 11: White matter - Signal transduction | Cluster 56: Non-specific - Sensory perception | Cluster 22: Non-specific - Basic cellular functions | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 6 | Low immune cell specificity | Detected in single | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,201 | 4 |
ENSG00000114019 | AMOTL2 | Angiomotin like 2 | [
"Q9Y2J4"
] | 3 | 134355347-134375479 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA063027"
] | [
"LCCP"
] | [
"Predicted intracellular proteins"
] | [
"Wnt signaling pathway"
] | [] | [] | [
"Cell Junctions"
] | [] | [] | [] | Approved | null | null | 61 | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 57: Podocytes - Glomerular filtration | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | 4,203 | 3 |
ENSG00000114021 | NIT2 | Nitrilase family member 2 | [
"Q9NQR4"
] | 3 | 100334739-100361635 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036999",
"HPA041289"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [] | [
"Cytosol"
] | [
"Centrosome"
] | [] | [] | Supported | Approved | null | 1 | null | null | Cluster 11: T-cells - Unknown function | Cluster 9: Non-specific - Receptor signaling | Cluster 63: Non-specific - Protein processing | Cluster 97: Non-specific - Cellular respiration | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 4,204 | 1 |
ENSG00000114023 | FAM162A | Family with sequence similarity 162 member A | [
"Q96A26"
] | 3 | 122384161-122412334 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035856",
"HPA075611"
] | [
"C3orf28",
"E2IG5"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Approved | null | 16 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 21: Non-specific - Metabolism | Cluster 15: Kidney cancer - Membrane components | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 4,205 | 3 |
ENSG00000114030 | KPNA1 | Karyopherin subunit alpha 1 | [
"P52294"
] | 3 | 122421902-122514945 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053627",
"HPA063426"
] | [
"IPOA5",
"NPI-1",
"RCH2",
"SRP1"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [
"Host-virus interaction",
"Protein transport",
"Transport"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | Supported | null | 158 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 14: Neurons - Synaptic function | Cluster 63: Non-specific - Protein processing | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,207 | 4 |
ENSG00000114062 | UBE3A | Ubiquitin protein ligase E3A | [
"Q05086"
] | 15 | 25333728-25439051 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009723",
"HPA039410",
"HPA040380"
] | [
"ANCR",
"AS",
"E6-AP",
"EPVE6AP",
"FLJ26981",
"HPVE6A"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Biological rhythms",
"Host-virus interaction",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 134 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 2: Neurons - Nucleosome | Cluster 58: Non-specific - Nuclear processes | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 4,209 | 6 |
ENSG00000114098 | ARMC8 | Armadillo repeat containing 8 | [
"Q8IUR7"
] | 3 | 138187248-138298384 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036996",
"HPA044869"
] | [
"DKFZP434A043",
"GID5",
"HSPC056",
"VID28"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Approved | null | 65 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 35: Non-specific - DNA binding | Cluster 63: Non-specific - Protein processing | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,210 | 5 |
ENSG00000114107 | CEP70 | Centrosomal protein 70 | [
"Q8NHQ1"
] | 3 | 138494344-138594538 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036941",
"HPA036942"
] | [
"BITE",
"FLJ13036"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Primary cilium",
"Cytosol"
] | [
"Centrosome",
"Basal body"
] | [] | [] | Approved | Enhanced | null | 232 | null | null | Cluster 24: Non-specific - Transcription | Cluster 31: Non-specific - Transcription | Cluster 59: Leukemia - T-cell receptor | Cluster 81: Alveolar cells - Lung function | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 10 | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Prostate Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Prostate Adenocarcinoma"
] | 4,211 | 6 |
ENSG00000114113 | RBP2 | Retinol binding protein 2 | [
"P50120"
] | 3 | 139452884-139480747 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035866"
] | [
"CRABP-II",
"CRBP2",
"CRBPII",
"RBPC2"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Transport"
] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Enhanced | null | null | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 7: Small intestine - Absorption and Digestion | Tissue enriched | Detected in many | 355 | Group enriched | Detected in many | 6 | Group enriched | Detected in many | 4 | Cell type enriched | Detected in many | 33 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,212 | 4 |
ENSG00000114115 | RBP1 | Retinol binding protein 1 | [
"P09455"
] | 3 | 139517434-139539829 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007338",
"CAB018603",
"CAB019276"
] | [
"CRABP-I",
"CRBP",
"CRBP1",
"CRBPI",
"RBPC"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Transport"
] | [] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Enhanced | null | 7 | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 32: Non-specific - Cell proliferation | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | 4,213 | 7 |
ENSG00000114120 | SLC25A36 | Solute carrier family 25 member 36 | [
"Q96CQ1"
] | 3 | 140941830-140980995 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA027036"
] | [
"FLJ10618",
"PNC2"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [] | [
"Mitochondria",
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | null | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 55: Myocytes - Oxidative muscle function | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 4,214 | 8 |
ENSG00000114126 | TFDP2 | Transcription factor Dp-2 | [
"Q14188"
] | 3 | 141944428-142149544 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB018396",
"HPA070399"
] | [
"Dp-2"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Cell cycle",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Vesicles",
"Mitotic spindle"
] | [] | [] | Supported | Supported | null | 17 | Yes | No | Cluster 22: Eosinophils - Transcription | Cluster 25: Non-specific - Transcription | Cluster 59: Leukemia - T-cell receptor | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 80: Thymus - Adaptive immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 4,217 | 4 |
ENSG00000114127 | XRN1 | 5'-3' exoribonuclease 1 | [
"Q8IZH2"
] | 3 | 142306607-142448062 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035005",
"HPA035006"
] | [
"SEP1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [
"DNA-binding",
"Exonuclease",
"Hydrolase",
"Nuclease",
"RNA-binding"
] | [
"Tumor suppressor"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 26 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 31: Non-specific - Transcription | Cluster 33: Sarcoma - Muscle contraction | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 4,218 | 8 |
ENSG00000114166 | KAT2B | Lysine acetyltransferase 2B | [
"Q92831"
] | 3 | 20040446-20154404 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002470",
"CAB004526",
"HPA055839",
"HPA073897"
] | [
"GCN5",
"GCN5L",
"P/CAF",
"PCAF"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"Cell cycle",
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Acyltransferase",
"Transferase"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | Supported | null | 144 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 19: Astrocytes - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 4,219 | 1 |
ENSG00000114200 | BCHE | Butyrylcholinesterase | [
"P06276"
] | 3 | 165772904-165837462 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001560"
] | [
"CHE1",
"CHE2",
"E1"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Serine esterase"
] | [
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Approved | null | 8 | null | null | null | Cluster 13: Oligodendrocytes - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 12 | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | 4,220 | 7 |
ENSG00000114204 | SERPINI2 | Serpin family I member 2 | [
"O75830"
] | 3 | 167441914-167478972 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"MEPI",
"PI14",
"TSA2004"
] | [
"Predicted secreted proteins"
] | [] | [
"Protease inhibitor",
"Serine protease inhibitor"
] | [] | [] | [] | [
"Secreted to digestive system"
] | [
"Enzyme inhibitor"
] | null | null | null | 7 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 8: Pancreas - Proteolysis | Tissue enriched | Detected in some | 265 | Cancer enriched | Detected in single | 5 | Cancer enriched | Detected in some | 6 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,221 | 5 |
ENSG00000114209 | PDCD10 | Programmed cell death 10 | [
"Q9BUL8"
] | 3 | 167683298-167734939 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027095"
] | [
"CCM3",
"TFAR15"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Angiogenesis",
"Apoptosis"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 49 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 28: Oligodendrocytes - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 47: Platelets - Hemostasis | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,222 | 6 |
ENSG00000114248 | LRRC31 | Leucine rich repeat containing 31 | [
"Q6UY01"
] | 3 | 169839172-169869935 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA058013"
] | [
"FLJ23259"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | null | null | 1 | null | null | null | null | Cluster 27: Breast cancer - Unknown function | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in some | null | Group enriched | Detected in some | 4 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,223 | 3 |
ENSG00000114251 | WNT5A | Wnt family member 5A | [
"P41221"
] | 3 | 55465715-55490539 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA072252"
] | [
"hWNT5A"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Chondrogenesis",
"Differentiation",
"Wnt signaling pathway"
] | [
"Developmental protein"
] | [
"Disease variant",
"Dwarfism"
] | [
"Microtubules",
"Mitotic spindle",
"Primary cilium"
] | [
"Nucleoli fibrillar center"
] | [
"Secreted to extracellular matrix"
] | [
"Developmental protein"
] | Uncertain | null | null | 3 | Yes | null | null | Cluster 20: Macrophages & Microglia - Immune response | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Colon Adenocarcinoma"
] | [] | [
"Colon Adenocarcinoma"
] | 4,224 | 2 |
ENSG00000114268 | PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | [
"Q16877"
] | 3 | 48517684-48562015 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047719",
"HPA066058"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Kinase",
"Multifunctional enzyme",
"Transferase"
] | [] | [
"Nucleoli"
] | [] | [] | [] | Approved | Uncertain | null | 16 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 6: Non-specific - Immune response | Cluster 69: Skin cancer - ECM organization | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 47: Testis - Mixed function | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 5 | 0 | 5 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Thyroid Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Thyroid Carcinoma"
] | 4,225 | 8 |
ENSG00000114270 | COL7A1 | Collagen type VII alpha 1 chain | [
"Q02388"
] | 3 | 48564073-48595329 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016357",
"HPA018877",
"HPA042420"
] | [
"EBD1",
"EBDCT",
"EBR1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [
"Protease inhibitor",
"Serine protease inhibitor"
] | [
"Disease variant",
"Epidermolysis bullosa"
] | [
"Endoplasmic reticulum"
] | [
"Vesicles"
] | [
"Secreted to extracellular matrix"
] | [
"Cell adhesion"
] | Approved | Enhanced | null | 6 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 72: Neuronal - Signal transduction | Cluster 26: Keratinocytes - Keratinization | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,226 | 3 |
ENSG00000114279 | FGF12 | Fibroblast growth factor 12 | [
"P61328"
] | 3 | 192139390-192767764 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA071557"
] | [
"FGF12B",
"FHF1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Growth factor"
] | [
"Disease variant",
"Epilepsy"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | null | null | 6 | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 35: Non-specific - Mixed function | Tissue enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 4,227 | 9 |
ENSG00000114302 | PRKAR2A | Protein kinase cAMP-dependent type II regulatory subunit alpha | [
"P13861"
] | 3 | 48744597-48847874 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005023",
"HPA038268"
] | [
"PRKAR2"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Centriolar satellite",
"Basal body",
"Mid piece"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Uncertain | Uncertain | null | 71 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 8: Non-specific - Basic cellular processes | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in all | 4 | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,228 | 4 |
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