LiteFold/InterPro · Datasets at Hugging Face

IPR061338

61,338

Putative pilus system protein FilF

Pilus_FilF

Family

196

false

FilF is found almost exclusively in the genus Acinetobacter and is assigned as a putative pilus assembly protein from local genomic contexts that include several additional putative pilus system proteins [ ].

[]

0

[ "NCBIFAM" ]

[ "NF050081" ]

[ "pilus_FilF" ]

[ 196 ]

1

[]

0

[]

0

[ "PUB00162658" ]

[ "29939498" ]

[ "Transcriptome analysis of Porphyromonas gingivalis and Acinetobacter baumannii in polymicrobial communities." ]

[ 2018 ]

1

[]

0

null

[ "Moraxellaceae" ]

[ 196 ]

1

[]

0

true

Family

Putative pilus system protein FilF

Pilus_FilF

6

IPR061339

61,339

LA_3696-like, N-terminal

LA_3696_Nterm

Domain

186

false

Members of this entry, found primarily but not exclusively in the genus Leptospira, share this homology region at the N-terminal, typically share a shorter C-terminal domain as well, and are variable in length and sequence between the two well-conserved regions. The function is unknown.

[]

0

[ "NCBIFAM" ]

[ "NF047472" ]

[ "LA_3696_Nterm" ]

[ 186 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "hot springs metagenome" ]

[ 184, 2 ]

2

[]

0

true

Domain

LA_3696-like, N-terminal

LA_3696_Nterm

4

IPR061340

61,340

LIC_13355-like lipoprotein

Lipo_LIC13355

Family

163

false

Members of this family are lipoproteins found broadly in the genus Leptospira.

[]

0

[ "NCBIFAM" ]

[ "NF033170" ]

[ "lipo_LIC13355" ]

[ 163 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Pseudomonadati" ]

[ 163 ]

1

[]

0

true

Family

LIC_13355-like lipoprotein

Lipo_LIC13355

8

IPR061341

61,341

LA_3334-like

LA_3334_fam

Family

160

false

This uncharacterised protein family is restricted to the genus Leptospira, and is named for LA_3334 ( ) from Leptospira interrogans serovar Lai str. 56601

[]

0

[ "NCBIFAM" ]

[ "NF047432" ]

[ "LA_3334_fam" ]

[ 160 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Leptospira" ]

[ 160 ]

1

[]

0

true

Family

LA_3334-like

LA_3334_fam

7

IPR061342

61,342

NF038215-like lipoprotein

Acineto_lipo_PV

Family

153

false

This small lipoprotein, about 60 amino acids long on average in precursor form, is widespread in the genus Acinetobacter. The motif PVxxxDY is conserved in most members. The function is unknown.

[]

0

[ "NCBIFAM" ]

[ "NF038215" ]

[ "acineto_lipo_PV" ]

[ 153 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Acinetobacter" ]

[ 153 ]

1

[]

0

true

Family

NF038215-like lipoprotein

Acineto_lipo_PV

7

IPR061343

61,343

Oligosaccharide repeat unit polymerase

Wzy_O6_O28

Family

154

false

Members of this family are oligosaccharide repeat unit polymerases in a subfamily that includes the Wzy proteins for polymerization of the O-antigens O6, O28, O39, O59, and several others [ ].

[]

0

[ "NCBIFAM" ]

[ "NF033860" ]

[ "Wzy_O6_O28" ]

[ 154 ]

1

[]

0

[]

0

[ "PUB00105376" ]

[ "17244797" ]

[ "Relationship between O-antigen subtypes, bacterial surface structures and O-antigen gene clusters in Escherichia coli O123 strains carrying genes for Shiga toxins and intimin." ]

[ 2007 ]

1

[]

0

null

[ "Pseudomonadati", "human gut metagenome" ]

[ 153, 1 ]

2

[]

0

true

Family

Oligosaccharide repeat unit polymerase

Wzy_O6_O28

3

IPR061345

61,345

PhiSA1p31 domain

PhiSA1p31

Domain

140

false

This domain occurs in Streptomyces and related lineages, in proteins with highly variable architectures, typically at or near the C-terminal. Member proteins include at least two from known temperate phage of Streptomyces, including phiSA1p31, for which it is named, from Streptomyces phage phiSASD1.

[]

0

[ "NCBIFAM" ]

[ "NF038082" ]

[ "phiSA1p31" ]

[ 140 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Actinomycetes", "Caudoviricetes", "Zophobas morio" ]

[ 131, 8, 1 ]

3

[]

0

true

Domain

PhiSA1p31 domain

PhiSA1p31

2

IPR061346

61,346

NF038120 family PEP-CTERM protein

PEP_CTERM_QFxxD

Family

136

false

This family of PEP-CTERM proteins has a notable motif, QFxxD, near the PEP-CTERM region, for which it is named.

[]

0

[ "NCBIFAM" ]

[ "NF038120" ]

[ "PEP_CTERM_QFxxD" ]

[ 136 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Pseudomonadati" ]

[ 136 ]

1

[]

0

true

Family

NF038120 family PEP-CTERM protein

PEP_CTERM_QFxxD

7

IPR061347

61,347

Mbov_0399 family ICE element protein

ICE_Mbov_0399

Family

139

false

Members of this family, such as Mbov_0399 from Mycoplasmopsis bovis, MAG3890 from Mycoplasma agalactiae, and SFLOR_RS04885 from Spiroplasma floricola, are large proteins from Integrating Conjugative Elements (ICE) of a type related to VirB-like type IV secretion systems and prevalent in the Mycoplasmatota [ ].

[]

0

[ "NCBIFAM" ]

[ "NF045892" ]

[ "ICE_Mbov_0399" ]

[ 139 ]

1

[]

0

[]

0

[ "PUB00159434" ]

[ "22693604" ]

[ "Comparative geno-plasticity analysis of Mycoplasma bovis HB0801 (Chinese isolate)." ]

[ 2012 ]

1

[]

0

null

[ "Mycoplasmatota" ]

[ 139 ]

1

[]

0

true

Family

Mbov_0399 family ICE element protein

ICE_Mbov_0399

9

IPR061348

61,348

NF038130 family PEP-CTERM protein

PEP_NF038130

Family

132

false

This family of PEP-CTERM proteins occurs in Cyanobacteria such as Nostoc, but also in floc-forming bacteria such as Zoogloea ramigera and Candidatus Accumulibacter phosphatis [ ].

[]

0

[ "NCBIFAM" ]

[ "NF038130" ]

[ "PEP_NF038130" ]

[ 132 ]

1

[]

0

[]

0

[ "PUB00060405" ]

[ "22037399" ]

[ "Archaeosortases and exosortases are widely distributed systems linking membrane transit with posttranslational modification." ]

[ 2012 ]

1

[]

0

null

[ "Bacteria" ]

[ 132 ]

1

[]

0

true

Family

NF038130 family PEP-CTERM protein

PEP_NF038130

6

IPR061349

61,349

Cistern family PEP-CTERM protein

PEP-cistern

Family

133

false

Members of this family are PEP-CTERM proteins, that is, surface proteins of Gram-negative organisms that carry a short C-terminal region used to help target proteins to their proper cellular location, hold them in position for post-translational modifications that might need to occur (such as glycosylation), and which ...

[]

0

[ "NCBIFAM" ]

[ "NF033947" ]

[ "PEP-cistern" ]

[ 133 ]

1

[]

0

[]

0

[ "PUB00060405" ]

[ "22037399" ]

[ "Archaeosortases and exosortases are widely distributed systems linking membrane transit with posttranslational modification." ]

[ 2012 ]

1

[]

0

null

[ "Bacteria" ]

[ 133 ]

1

[]

0

true

Family

Cistern family PEP-CTERM protein

PEP-cistern

8

IPR061350

61,350

GapS4b-like

Antiphage_GapS4b

Family

130

false

Proteins of this family are homologues of the anti-phage protein GapS4b in Vibrio parahaemolyticus [ ].

[]

0

[ "NCBIFAM" ]

[ "NF047934" ]

[ "antiphage_GapS4b" ]

[ 130 ]

1

[]

0

[]

0

[ "PUB00161243" ]

[ "39443754" ]

[ "Gamma-Mobile-Trio systems are mobile elements rich in bacterial defensive and offensive tools." ]

[ 2024 ]

1

[]

0

null

[ "Bacteria" ]

[ 130 ]

1

[]

0

true

Family

GapS4b-like

Antiphage_GapS4b

4

IPR061351

61,351

LIC_10494-like lipoprotein

Lipo_LIC10494

Family

128

false

Members of this family are lipoproteins found broadly in the genus Leptospira.

[]

0

[ "NCBIFAM" ]

[ "NF033169" ]

[ "lipo_LIC10494" ]

[ 128 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Leptospira" ]

[ 128 ]

1

[]

0

true

Family

LIC_10494-like lipoprotein

Lipo_LIC10494

8

IPR061353

61,353

MHFG family PEP-CTERM protein

PEP_CTERM_MHFG

Family

126

false

This PEP-CTERM protein, dependent on exosortase for processing and export, is named for a distinctive MHFG motif.

[]

0

[ "NCBIFAM" ]

[ "NF038119" ]

[ "PEP_CTERM_MHFG" ]

[ 126 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Burkholderiales", "Tanacetum cinerariifolium" ]

[ 125, 1 ]

2

[]

0

true

Family

MHFG family PEP-CTERM protein

PEP_CTERM_MHFG

4

IPR061354

61,354

Lipoprotein LipL21

Lipo_LipL21

Family

132

false

Members of this family are lipoprotein LipL21, as described in Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 but found broadly in the genus Leptospira. Close homologs that are not lipoproteins by sequence are likely defective in their reported coding region.

[]

0

[ "NCBIFAM" ]

[ "NF033162" ]

[ "lipo_LipL21" ]

[ 132 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Leptospiraceae" ]

[ 132 ]

1

[]

0

true

Family

Lipoprotein LipL21

Lipo_LipL21

3

IPR061355

61,355

Lipoprotein LipL46

Lipo_LipL46

Family

120

false

Members of this family are lipoprotein LipL46, as described in Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 but found broadly in the genus Leptospira. Close homologs that are not lipoproteins by sequence are likely defective in their reported coding region.

[]

0

[ "NCBIFAM" ]

[ "NF033164" ]

[ "lipo_LipL46" ]

[ 120 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Leptospira" ]

[ 120 ]

1

[]

0

true

Family

Lipoprotein LipL46

Lipo_LipL46

4

IPR061356

61,356

LIC11755 lipoprotein

Lipo_LIC11755

Family

121

false

LIC11755 proteins are predicted to be surface-exposed outer membrane lipoproteins of the genus Leptospira. Shorter members of this family average about 700 amino acids, while longer versions have an additional C-terminal region of 250 to 300 amino acids.

[]

0

[ "NCBIFAM" ]

[ "NF047473" ]

[ "lipo_LIC11755" ]

[ 121 ]

1

[]

0

[]

0

[ "PUB00105762" ]

[ "28496441" ]

[ "Discovery of Novel Leptospirosis Vaccine Candidates Using Reverse and Structural Vaccinology." ]

[ 2017 ]

1

[]

0

null

[ "Leptospira" ]

[ 121 ]

1

[]

0

true

Family

LIC11755 lipoprotein

Lipo_LIC11755

4

IPR061357

61,357

Flagellar basal body rod modification protein

PRK12812.1

Family

119

false

This entry represents a family of Flagellar basal body rod modification proteins. They act as a scaffold for the assembly of hook proteins onto the flagellar basal body rod.

[]

0

[ "NCBIFAM" ]

[ "NF009452" ]

[ "PRK12812.1" ]

[ 119 ]

1

[]

0

[]

0

[ "PUB00104831", "PUB00104832" ]

[ "11298288", "14617189" ]

[ "Transposon mutagenesis of Campylobacter jejuni identifies a bipartite energy taxis system required for motility.", "Transcription of sigma54-dependent but not sigma28-dependent flagellar genes in Campylobacter jejuni is associated with formation of the flagellar secretory apparatus." ]

[ 2001, 2003 ]

2

[]

0

null

[ "Pseudomonadati" ]

[ 119 ]

1

[]

0

true

Family

Flagellar basal body rod modification protein

PRK12812.1

9

IPR061358

61,358

LIC11469 lipoprotein adhesin Lsa20

LIC11469_Lsa20

Family

112

false

It has been reported that the Lsa20 protein from L. interrogans serovar Copenhageni strain M20 bound to laminin and human plasminogen [ ]. It is predicted to be a lipoprotein.

[]

0

[ "NCBIFAM" ]

[ "NF047614" ]

[ "LIC11469_fam" ]

[ 112 ]

1

[]

0

[]

0

[ "PUB00159370" ]

[ "21844229" ]

[ "The novel leptospiral surface adhesin Lsa20 binds laminin and human plasminogen and is probably expressed during infection." ]

[ 2011 ]

1

[]

0

null

[ "Leptospiraceae" ]

[ 112 ]

1

[]

0

true

Family

LIC11469 lipoprotein adhesin Lsa20

LIC11469_Lsa20

2

IPR061359

61,359

LIC_10705 lipoprotein

Lipo_LIC_10705

Family

102

false

The LIC_10705 family of lipoproteins, found in the genus Leptospira, includes tandem-encoded paralogs such as LIC_10705 and LIC_10706 in L. interrogans serovar Copenhageni str. Fiocruz L1-130.

[]

0

[ "NCBIFAM" ]

[ "NF038393" ]

[ "lipo_LIC_10705" ]

[ 102 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Leptospira" ]

[ 102 ]

1

[]

0

true

Family

LIC_10705 lipoprotein

Lipo_LIC_10705

7

IPR061361

61,361

Exosortase Y-associated Wzy-like protein

XrtY_assoc_Wzy

Family

93

false

Members of this family are encoded in a surface polysaccharide biosynthesis locus that also includes the putative protein-sorting endopeptidase exosortase Y (NF046083). Members show distant relatedness to oligosaccharide repeat unit polymerases such as Wzy proteins of O-antigen biosynthesis.

[]

0

[ "NCBIFAM" ]

[ "NF046084" ]

[ "XrtY_assoc_Wzy" ]

[ 93 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteroidota" ]

[ 93 ]

1

[]

0

true

Family

Exosortase Y-associated Wzy-like protein

XrtY_assoc_Wzy

3

IPR061362

61,362

Ecr-like regulatory small membrane protein

Ecr-like_memb

Family

90

false

Ecr, as described in the genus Enterobacter, is a small membrane protein predicted to span the inner membrane. It was found to modulate expression of PhoP, part of the PhoP-PhoQ two component system, which in turn induces the arnBCADTEF operon, leading to modification of LPS and conferring elevated resistance to colist...

[]

0

[ "NCBIFAM" ]

[ "NF033861" ]

[ "sm_mem_Ecr" ]

[ 90 ]

1

[]

0

[]

0

[ "PUB00105377" ]

[ "31169899" ]

[ "Heterogeneous resistance to colistin in Enterobacter cloacae complex due to a new small transmembrane protein." ]

[ 2019 ]

1

[]

0

null

[ "Gammaproteobacteria" ]

[ 90 ]

1

[]

0

true

Family

Ecr-like regulatory small membrane protein

Ecr-like_memb

9

IPR061363

61,363

Myxosortase-dependent M36 metallopeptidase

Myxo_dep_M36

Family

86

false

Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin ( ), and a C-terminal MYXO-CTERM domain ( ), suggesting processing and surface-anchoring by a type II CAAX prenyl protease-related sorting enzyme, myxosortase. Members of this family include MXAN_3564 (mepA), part of th...

[]

0

[ "NCBIFAM" ]

[ "NF038112" ]

[ "myxo_dep_M36" ]

[ 86 ]

1

[]

0

[]

0

[ "PUB00103726", "PUB00105566" ]

[ "31975447", "25250022" ]

[ "MYXO-CTERM sorting tag directs proteins to the cell surface via the type II secretion system.", "The lethal cargo of Myxococcus xanthus outer membrane vesicles." ]

[ 2020, 2014 ]

2

[]

0

null

[ "Pseudomonadati" ]

[ 86 ]

1

[]

0

true

Family

Myxosortase-dependent M36 metallopeptidase

Myxo_dep_M36

2

IPR061364

61,364

Antiviral RADAR system adenosine triphosphatase RdrA

RdrA

Family

84

false

Proteins of this family are the essential components of the anti-phage system RADAR (restriction by an adenosine deaminase acting on RNA). RADAR mediates RNA editing in response to phage infections.

[]

0

[ "NCBIFAM" ]

[ "NF041743" ]

[ "RdrA" ]

[ 84 ]

1

[]

0

[]

0

[ "PUB00152882" ]

[ "32855333" ]

[ "Diverse enzymatic activities mediate antiviral immunity in prokaryotes." ]

[ 2020 ]

1

[]

0

null

[ "Pseudomonadati" ]

[ 84 ]

1

[]

0

true

Family

Antiviral RADAR system adenosine triphosphatase RdrA

RdrA

3

IPR061365

61,365

Chryseobasin-related MNIO class RiPP peptide

ChrA-rel_RiPP

Family

78

false

Members of this family closely resemble the chryseobasin RiPP precursor ChrA, especially in having the seven C-terminal residues as CP[GA]CG[LM]G. However, the central region differs greatly, is substantially shorter, and contains an invariant Cys residue whose significance is not yet clear. Members are found in multip...

[]

0

[ "NCBIFAM" ]

[ "NF050125" ]

[ "ChrA_rel_RiPP" ]

[ 78 ]

1

[]

0

[]

0

[ "PUB00153338" ]

[ "37252350" ]

[ "Macrocyclization and Backbone Rearrangement During RiPP Biosynthesis by a SAM-Dependent Domain-of-Unknown-Function 692." ]

[ 2023 ]

1

[]

0

null

[ "Bacteroidota" ]

[ 78 ]

1

[]

0

true

Family

Chryseobasin-related MNIO class RiPP peptide

ChrA-rel_RiPP

9

IPR061368

61,368

Scytonemin biosynthesis cyclase/decarboxylase ScyC

Scytonem_ScyC

Family

69

false

Of the various markers of scytonemin biosynthesis, ScyC appears to be the clearest, as there are few or no close homologs from outside of the set of confidently predicted scytonemin producer bacteria. ScyC, an enzyme in the biosynthesis pathway for the cyanobacterial natural sunscreen scytonemin, performs a cyclization...

[]

0

[ "NCBIFAM" ]

[ "NF035924" ]

[ "scytonem_ScyC" ]

[ 69 ]

1

[]

0

[]

0

[ "PUB00105457" ]

[ "18954141" ]

[ "Investigating the initial steps in the biosynthesis of cyanobacterial sunscreen scytonemin." ]

[ 2008 ]

1

[]

0

null

[ "Bacteria" ]

[ 69 ]

1

[]

0

true

Family

Scytonemin biosynthesis cyclase/decarboxylase ScyC

Scytonem_ScyC

9

IPR061369

61,369

BN159_2729 protein

BN159_2729-like

Family

67

false

This uncharacterised protein family occurs in Streptomyces and related species. Some members have insertions of long stretches of low-complexity sequences.

[]

0

[ "NCBIFAM" ]

[ "NF038081" ]

[ "BN159_2729_fam" ]

[ 67 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Streptomycetaceae" ]

[ 67 ]

1

[]

0

true

Family

BN159_2729 protein

BN159_2729-like

5

IPR061371

61,371

MEMAR_RS02690 S-layer glycoprotein

S_layer_MEMAR

Family

69

false

Members of this family are archaeal S-layer glycoproteins in the family of MEMAR_RS02690. Most members of this family have the PGF-CTERM domain, recognized and processed by the archaeosortase A (ArtA). Surprisingly, while MEMAR_RS02690 itself, from Methanoculleus marisnigri, a methanogen from the Order Methanomicrobial...

[]

0

[ "NCBIFAM" ]

[ "NF041431" ]

[ "S_layer_MEMAR" ]

[ 69 ]

1

[]

0

[]

0

[ "PUB00106393" ]

[ "35481895" ]

[ "Characterizing the N- and O-linked glycans of the PGF-CTERM sorting domain-containing S-layer protein of Methanoculleus marisnigri." ]

[ 2022 ]

1

[]

0

null

[ "Methanomicrobiales", "hydrocarbon metagenome" ]

[ 67, 2 ]

2

[]

0

true

Family

MEMAR_RS02690 S-layer glycoprotein

S_layer_MEMAR

7

IPR061374

61,374

LEVG PEP-CTERM protein

PEP_CTERM_LEVG

Family

61

false

This well-conserved family of PEP-CTERM proteins occurs in Cyanobacteria.

[]

0

[ "NCBIFAM" ]

[ "NF038121" ]

[ "PEP_CTERM_LEVG" ]

[ 61 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Cyanophyceae" ]

[ 61 ]

1

[]

0

true

Family

LEVG PEP-CTERM protein

PEP_CTERM_LEVG

1

IPR061375

61,375

Bgr_08870 protein, N-terminal

Bgr08870_N

Domain

61

false

This entry describes the N-terminal region of Bgr_08870 from Bartonella grahamii. Homologs appear restricted to other species of the same genus. The C-terminal region includes extensive low-complexity sequence, but also regions of homology with other at least one other family of Bartonella proteins.

[]

0

[ "NCBIFAM" ]

[ "NF041327" ]

[ "Bgr08870_fam" ]

[ 61 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bartonella" ]

[ 61 ]

1

[]

0

true

Domain

Bgr_08870 protein, N-terminal

Bgr08870_N

7

IPR061376

61,376

GapS6b protein

GapS6b-like

Family

60

false

Proteins of this family are homologs of the anti-phage protein GapS6b in Vibrio parahaemolyticus.

[]

0

[ "NCBIFAM" ]

[ "NF047936" ]

[ "antiphage_GapS6b" ]

[ 60 ]

1

[]

0

[]

0

[ "PUB00161243" ]

[ "39443754" ]

[ "Gamma-Mobile-Trio systems are mobile elements rich in bacterial defensive and offensive tools." ]

[ 2024 ]

1

[]

0

null

[ "Pseudomonadati" ]

[ 60 ]

1

[]

0

true

Family

GapS6b protein

GapS6b-like

6

IPR061377

61,377

Lipoprotein LipL36

LipL36

Family

60

false

Members of this family are lipoprotein LipL36, as described in Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 but found broadly in the genus Leptospira. Close homologs that are not lipoproteins by sequence are likely defective in their reported coding region.

[]

0

[ "NCBIFAM" ]

[ "NF033160" ]

[ "lipo_LipL36" ]

[ 60 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Leptospira" ]

[ 60 ]

1

[]

0

true

Family

Lipoprotein LipL36

LipL36

2

IPR061378

61,378

LA_3150 lipoprotein

LA_3150-like

Family

56

false

Members of this lipoprotein family average 150 amino acids in length, and occur only in the genus Leptospira. In addition to the conserved Cys residue of the lipoprotein signal peptide, four additional invariant Cys residues are found.

[]

0

[ "NCBIFAM" ]

[ "NF047459" ]

[ "LA_3150_fam_lipo" ]

[ 56 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Leptospira" ]

[ 56 ]

1

[]

0

true

Family

LA_3150 lipoprotein

LA_3150-like

1

IPR061379

61,379

Adventurous gliding motility lipoprotein CglC

CglC

Family

52

false

CglC (cell contact-dependent gliding (or conditional gliding) motility protein C, also called adventurous gliding motility protein AgmO, is found in delta-proteobacterial species that exhibit a taxonomically restricted form of gliding motility.

[]

0

[ "NCBIFAM" ]

[ "NF033754" ]

[ "gliding_CglC" ]

[ 52 ]

1

[]

0

[]

0

[ "PUB00105302", "PUB00105303" ]

[ "22343295", "26132848" ]

[ "Identification of the cglC, cglD, cglE, and cglF genes and their role in cell contact-dependent gliding motility in Myxococcus xanthus.", "Contact- and Protein Transfer-Dependent Stimulation of Assembly of the Gliding Motility Machinery in Myxococcus xanthus." ]

[ 2012, 2015 ]

2

[]

0

null

[ "Cystobacterineae" ]

[ 52 ]

1

[]

0

true

Family

Adventurous gliding motility lipoprotein CglC

CglC

5

IPR061380

61,380

TRP75-like N-terminal

TRP75_N

Domain

53

false

This N-terminal domain is found in TRP75 (tandem repeat protein, 75 kDa) of Ehrlichia chaffeensis and TRP95 of Ehrlichia canis, preceding the region of 24 amino acid long direct repeats. It appears also in non-repetitive proteins from Anaplasma and Wolbachia, which likewise are members of the alphaproteobacteria.

[]

0

[ "NCBIFAM" ]

[ "NF038243" ]

[ "TRP75_fam_Nterm" ]

[ 53 ]

1

[]

0

[]

0

[ "PUB00105646", "PUB00105647" ]

[ "21606187", "29643078" ]

[ "Tyrosine-phosphorylated Ehrlichia chaffeensis and Ehrlichia canis tandem repeat orthologs contain a major continuous cross-reactive antibody epitope in lysine-rich repeats.", "Ehrlichia chaffeensis TRP75 Interacts with Host Cell Targets Involved in Homeostasis, Cytoskeleton Organization, and Apoptosis Regulation...

[ 2011, 2018 ]

2

[]

0

null

[ "Anaplasmataceae", "Eukaryota" ]

[ 43, 10 ]

2

[]

0

true

Domain

TRP75-like N-terminal

TRP75_N

3

IPR061381

61,381

Adventurous gliding motility protein GltG

GltG

Family

52

false

GltG proteins, including the founding member MXAN_4867 from Myxococcus xanthus, occur in certain delta-proteobacteria and are involved in adventurous gliding (A-)motility. GltG has an N-terminal forkhead-associated (FHA) domain domain, often associated with signal transduction.

[]

0

[ "NCBIFAM" ]

[ "NF033760" ]

[ "gliding_GltG" ]

[ 52 ]

1

[]

0

[]

0

[ "PUB00105303" ]

[ "26132848" ]

[ "Contact- and Protein Transfer-Dependent Stimulation of Assembly of the Gliding Motility Machinery in Myxococcus xanthus." ]

[ 2015 ]

1

[]

0

null

[ "Cystobacterineae" ]

[ 52 ]

1

[]

0

true

Family

Adventurous gliding motility protein GltG

GltG

7

IPR061382

61,382

Adventurous gliding motility protein GltJ

GltJ

Family

50

false

Adventurous gliding motility protein GltJ, also known as AgmX, occurs in delta-proteobacteria such as Myxococcus xanthus.

[]

0

[ "NCBIFAM" ]

[ "NF033761" ]

[ "gliding_GltJ" ]

[ 50 ]

1

[]

0

[]

0

[ "PUB00105303" ]

[ "26132848" ]

[ "Contact- and Protein Transfer-Dependent Stimulation of Assembly of the Gliding Motility Machinery in Myxococcus xanthus." ]

[ 2015 ]

1

[]

0

null

[ "Cystobacterineae" ]

[ 50 ]

1

[]

0

true

Family

Adventurous gliding motility protein GltJ

GltJ

8

IPR061383

61,383

BAR domain-like protein A BdpA

BdpA

Family

47

false

BdpA is required for uniform size distribution of membrane vesicles and influences scaffolding of (outer membrane extensions) OMEs into a consistent diameter and curvature.

[]

0

[ "NCBIFAM" ]

[ "NF049843" ]

[ "BdpA" ]

[ 47 ]

1

[]

0

[]

0

[ "PUB00162648" ]

[ "34643180" ]

[ "A bacterial membrane sculpting protein with BAR domain-like activity." ]

[ 2021 ]

1

[]

0

null

[ "Gammaproteobacteria", "uncultured organism" ]

[ 46, 1 ]

2

[]

0

true

Family

BAR domain-like protein A BdpA

BdpA

4

IPR061384

61,384

RadB lipoprotein

RadB

Family

47

false

The small lipoprotein RadB, as found in Fusobacterium nucleatum, is encoded between the genes for the lipoprotein FAD-I and the large adhesin RadD. The name RapB (RadD-Associated Proteins B) was also suggested for RadB.

[]

0

[ "NCBIFAM" ]

[ "NF041844" ]

[ "lipo_RadB_fam" ]

[ 47 ]

1

[]

0

[]

0

[ "PUB00152951", "PUB00152979" ]

[ "31906541", "34074747" ]

[ "Role of FAD-I in Fusobacterial Interspecies Interaction and Biofilm Formation.", "Genetic and molecular determinants of polymicrobial interactions in Fusobacterium nucleatum." ]

[ 2020, 2021 ]

2

[]

0

null

[ "Fusobacterium" ]

[ 47 ]

1

[]

0

true

Family

RadB lipoprotein

RadB

8

IPR061385

61,385

Rhombosortase-dependent M36 metallopeptidase

Rhom_dep_M36

Family

47

false

Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal GlyGly-CTERM domain, recognized and cleaved by rhombosortase.

[]

0

[ "NCBIFAM" ]

[ "NF038111" ]

[ "rhom_dep_M36" ]

[ 47 ]

1

[]

0

[]

0

[ "PUB00060404", "PUB00105565" ]

[ "22194940", "30352106" ]

[ "GlyGly-CTERM and rhombosortase: a C-terminal protein processing signal in a many-to-one pairing with a rhomboid family intramembrane serine protease.", "C-terminal processing of GlyGly-CTERM containing proteins by rhombosortase in Vibrio cholerae." ]

[ 2011, 2018 ]

2

[]

0

null

[ "Gammaproteobacteria" ]

[ 47 ]

1

[]

0

true

Family

Rhombosortase-dependent M36 metallopeptidase

Rhom_dep_M36

9

IPR061386

61,386

Outer membrane exchange protein TraB

TraB_OM

Family

50

false

TraB, as described originally in the delta-proteobacterium, is a protein with a C-terminal OmpA-like domain, and is encoded in an operon with TraA. Together TraAB make it possible for bacterial cells with close enough kinship to exchange outer membrane lipoproteins, such that certain motility defects in mutant cells ca...

[]

0

[ "NCBIFAM" ]

[ "NF033763" ]

[ "exchanger_TraB" ]

[ 50 ]

1

[]

0

[]

0

[ "PUB00074074" ]

[ "22511878" ]

[ "Cell contact-dependent outer membrane exchange in myxobacteria: genetic determinants and mechanism." ]

[ 2012 ]

1

[]

0

null

[ "Cystobacterineae" ]

[ 50 ]

1

[]

0

true

Family

Outer membrane exchange protein TraB

TraB_OM

6

IPR061388

61,388

NGK_0946 protein

NGK_0946-like

Family

41

false

Members of this family including the apparent lipoprotein NGK_0946, found to be one of the most highly expressed proteins in the gonorrhea-causing pathogen Neisseria gonorrhoeae in the female genital tract.

[]

0

[ "NCBIFAM" ]

[ "NF046038" ]

[ "NGK_0946_fam" ]

[ 41 ]

1

[]

0

[]

0

[ "PUB00159667" ]

[ "26244506" ]

[ "The Gonococcal Transcriptome during Infection of the Lower Genital Tract in Women." ]

[ 2015 ]

1

[]

0

null

[ "Pseudomonadati", "hydrothermal vent metagenome" ]

[ 40, 1 ]

2

[]

0

true

Family

NGK_0946 protein

NGK_0946-like

7

IPR061389

61,389

Collagen-binding adhesin Cnm

Cnm

Family

40

false

This entry describes the non-repetitive region of the collagen-binding adhesin Cnm from the N terminus to just before the start of the glycosylated Thr-rich repeat region. The length of the repeat region is highly variable. Cnm is found in about 20 percent of strains of the dental caries-causing oral pathogen Streptoco...

[]

0

[ "NCBIFAM" ]

[ "NF050822" ]

[ "collag_bnd_Cnm" ]

[ 40 ]

1

[]

0

[]

0

[ "PUB00162710", "PUB00162711", "PUB00162712", "PUB00162713" ]

[ "36862654", "34406827", "15218042", "36708081" ]

[ "cnm-positive Streptococcus mutans is associated with galactose-deficient IgA in patients with IgA nephropathy.", "Amyloid Aggregation of Streptococcus mutans Cnm Influences Its Collagen-Binding Activity.", "Streptococcus mutans strains harboring collagen-binding adhesin.", "Harboring Cnm-expressing Streptoco...

[ 2023, 2021, 2004, 2023 ]

4

[]

0

null

[ "Streptococcus mutans" ]

[ 40 ]

1

[]

0

true

Family

Collagen-binding adhesin Cnm

Cnm

2

IPR061390

61,390

von Willebrand factor binding protein Vwb

Vwb

Family

43

false

The von Willebrand factor binding protein Vwb, like its paralog staphylocoagulase, is a coagulase and a virulence factor. It induces clotting, not by being an enzyme, but by activating prothrombin to generate fibrin.

[]

0

[ "NCBIFAM" ]

[ "NF033750" ]

[ "vWF_bind_Staph" ]

[ 43 ]

1

[]

0

[]

0

[ "PUB00105297", "PUB00105298" ]

[ "12101292", "28182324" ]

[ "A novel von Willebrand factor binding protein expressed by Staphylococcus aureus.", "Clumping factor A, von Willebrand factor-binding protein and von Willebrand factor anchor Staphylococcus aureus to the vessel wall." ]

[ 2002, 2017 ]

2

[]

0

null

[ "Staphylococcus" ]

[ 43 ]

1

[]

0

true

Family

von Willebrand factor binding protein Vwb

Vwb

4

IPR061391

61,391

FTN_0109 protein

FTN_0109-like

Family

39

false

It has been shown that proteins of this family were involved in F. tularensis virulence in Drosophila.

[]

0

[ "NCBIFAM" ]

[ "NF049881" ]

[ "FTN_0109_fam" ]

[ 39 ]

1

[]

0

[]

0

[ "PUB00162993", "PUB00162994" ]

[ "22368770", "20479082" ]

[ "The Drosophila melanogaster host model.", "Directed screen of Francisella novicida virulence determinants using Drosophila melanogaster." ]

[ 2012, 2010 ]

2

[]

0

null

[ "Francisellaceae" ]

[ 39 ]

1

[]

0

true

Family

FTN_0109 protein

FTN_0109-like

9

IPR061392

61,392

Pilin subunit UpsA

UpsA

Family

39

false

Proteins of this family are encoded by the archaeal upsA gene on the UV-inducible pili operon (ups operon), which is involved in UV-induced pili assembly, cellular aggregation, and subsequent DNA exchange between cells. UpsA and UpsB are major pilin subunits in the ups pili.

[]

0

[ "NCBIFAM" ]

[ "NF046073" ]

[ "UpsA" ]

[ 39 ]

1

[]

0

[]

0

[ "PUB00159058" ]

[ "24106028" ]

[ "Molecular analysis of the UV-inducible pili operon from Sulfolobus acidocaldarius." ]

[ 2013 ]

1

[]

0

null

[ "Archaea" ]

[ 39 ]

1

[]

0

true

Family

Pilin subunit UpsA

UpsA

7

IPR061393

61,393

Outer membrane exchange accessory lipoprotein TraC

TraC_OM

Family

45

false

This lipoprotein family, found Myxococcus xanthus and other members of the Myxococcocales branch of the Deltaproteobacteria, is involved in a kinship recognition-dependent system for exchange of outer membrane lipoproteins. TraC is described as an accessory protein to the TraAB pair that was shown to be critical to out...

[]

0

[ "NCBIFAM" ]

[ "NF040658" ]

[ "Myxo_OME_TraC" ]

[ 45 ]

1

[]

0

[]

0

[ "PUB00105882" ]

[ "34517761" ]

[ "Modular Lipoprotein Toxins Transferred by Outer Membrane Exchange Target Discrete Cell Entry Pathways." ]

[ 2021 ]

1

[]

0

null

[ "Cystobacterineae" ]

[ 45 ]

1

[]

0

true

Family

Outer membrane exchange accessory lipoprotein TraC

TraC_OM

5

IPR061394

61,394

Pilin subunit UpsB

UpsB

Family

38

false

Proteins of this family are encoded by the archaeal upsB gene on the UV-inducible pili operon (ups operon), which is involved in UV-induced pili assembly, cellular aggregation, and subsequent DNA exchange between cells. UpsA and UpsB are major pilin subunits in the ups pili.

[]

0

[ "NCBIFAM" ]

[ "NF046074" ]

[ "UpsB" ]

[ 38 ]

1

[]

0

[]

0

[ "PUB00159058" ]

[ "24106028" ]

[ "Molecular analysis of the UV-inducible pili operon from Sulfolobus acidocaldarius." ]

[ 2013 ]

1

[]

0

null

[ "Sulfolobaceae" ]

[ 38 ]

1

[]

0

true

Family

Pilin subunit UpsB

UpsB

1

IPR061395

61,395

DISARM system helicase DrmA, long form

DISARM_DrmAL

Family

37

false

This entry describes some DrmA helicases from class II DISARM anti-phage systems, and none from class I systems. Members distinguished from the shorter, more common form ( ) both by sequence divergence in regions that align and by an insert that makes members of this set longer.

[]

0

[ "NCBIFAM" ]

[ "NF038326" ]

[ "DISARM_DrmAL" ]

[ 37 ]

1

[]

0

[]

0

[ "PUB00105719" ]

[ "29085076" ]

[ "DISARM is a widespread bacterial defence system with broad anti-phage activities." ]

[ 2018 ]

1

[]

0

null

[ "Archaea", "Bacteria" ]

[ 16, 21 ]

2

[]

0

true

Family

DISARM system helicase DrmA, long form

DISARM_DrmAL

9

IPR061396

61,396

S-layer protein SlpA

SlpA

Family

37

false

In Clostridiodes difficile, the S-layer protein precursor, SlpA, is one member of a large paralogous family of protein that share several cell wall-binding repeats. SlpA is cleaved into a larger and smaller protein. The S-layer protein itself is important to adhesion, and portions of it are highly variable, and then N-...

[]

0

[ "NCBIFAM" ]

[ "NF033435" ]

[ "S-layer_Clost" ]

[ 37 ]

1

[]

0

[ "7acx", "7acy", "7acz", "7qgq", "8bby", "9f8f" ]

6

[ "PUB00051147", "PUB00105102" ]

[ "19183279", "12081960" ]

[ "Structural insights into the molecular organization of the S-layer from Clostridium difficile.", "Patterns of sequence conservation in the S-Layer proteins and related sequences in Clostridium difficile." ]

[ 2009, 2002 ]

2

[]

0

null

[ "Clostridioides difficile" ]

[ 37 ]

1

[]

0

true

Family

S-layer protein SlpA

SlpA

9

IPR061397

61,397

Francisella virulence factor A

FvfA

Family

36

false

It has been reported that members of this family play a role in protection of Francisella from osmotic shock and its survival in macrophages.

[]

0

[ "NCBIFAM" ]

[ "NF049880" ]

[ "FvfA" ]

[ 36 ]

1

[]

0

[ "5evf", "5evg" ]

2

[ "PUB00162991", "PUB00162992" ]

[ "25987704", "28994410" ]

[ "Identifying Francisella tularensis genes required for growth in host cells.", "Structure of the conserved Francisella virulence protein FvfA." ]

[ 2015, 2017 ]

2

[]

0

null

[ "Thiotrichales" ]

[ 36 ]

1

[]

0

true

Family

Francisella virulence factor A

FvfA

6

IPR061398

61,398

Cell-cell cohesion protein MtsD

MtsD

Family

36

false

MtsD belongs to the six gene mts (myxococcus thrombospondin D) operon, and is one of four with repeats described as thrombospondin type 3 (TSP3) repeats. Members of the locus participate in cell-cell cohesion that contributes to social motility and fruiting-body development, among other processes.

[]

0

[ "NCBIFAM" ]

[ "NF047639" ]

[ "throspo3_MtsD" ]

[ 36 ]

1

[]

0

[]

0

[ "PUB00159597" ]

[ "17720782" ]

[ "New locus important for Myxococcus social motility and development." ]

[ 2007 ]

1

[]

0

null

[ "Cystobacterineae" ]

[ 36 ]

1

[]

0

true

Family

Cell-cell cohesion protein MtsD

MtsD

6

IPR061399

61,399

PTPDL protein

PTPDL-like

Family

35

false

This protein family, named for its best conserved motif, appears exclusively in the Verrucomicrobiota. Some members have C-terminal suffix region with a resemblance to sorting signals.

[]

0

[ "NCBIFAM" ]

[ "NF041881" ]

[ "PTPDL_fam" ]

[ 35 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Verrucomicrobiota" ]

[ 35 ]

1

[]

0

true

Family

PTPDL protein

PTPDL-like

9

IPR061400

61,400

LBF_0142 lipoprotein

LBF_0142-like

Family

34

false

This subfamily of lipoproteins, named for LBF_0142 from the saprophytic species Leptospira biflexa, is found in a subset of Leptospira species, with additional members found outside the genus. Members belong to the broader DUF6503 family described by PF20113.2.

[]

0

[ "NCBIFAM" ]

[ "NF047762" ]

[ "lipo_LBF_0142" ]

[ 34 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Pseudomonadati" ]

[ 34 ]

1

[]

0

true

Family

LBF_0142 lipoprotein

LBF_0142-like

1

IPR061401

61,401

Serine-rich aggregation substance UasX

Agg_sub_LPXTH

Family

28

false

Members of this protein family are repetitive, serine-rich surface proteins of the Firmicutes, found primarily in the genus Leuconostoc. The variant form of sortase signal, LPXTH, is replaced by LPXTG in members from some lineages, such as Weissella oryzae, and therefore recognizable. Some members of this family have t...

[]

0

[ "NCBIFAM" ]

[ "NF035936" ]

[ "agg_sub_LPXTH" ]

[ 28 ]

1

[]

0

[]

0

[ "PUB00105460" ]

[ "25013139" ]

[ "Draft Genome Sequence of Weissella oryzae SG25T, Isolated from Fermented Rice Grains." ]

[ 2014 ]

1

[]

0

null

[ "Lactobacillaceae" ]

[ 28 ]

1

[]

0

true

Family

Serine-rich aggregation substance UasX

Agg_sub_LPXTH

9

IPR061402

61,402

FTL_1293 small RNA FtrC-regulated protein

FTL_1293-like

Family

27

false

It has been reported that the small RNA FtrC (Francisella tularensis RNA C) binds to FTL_1293 family proteins and regulate their expression. However, FTL_1293 is not required for F. tularensis virulence in vitro or in vivo.

[]

0

[ "NCBIFAM" ]

[ "NF049902" ]

[ "FTL_1293_fam" ]

[ 27 ]

1

[]

0

[]

0

[ "PUB00159254" ]

[ "22848684" ]

[ "Identification of a novel small RNA modulating Francisella tularensis pathogenicity." ]

[ 2012 ]

1

[]

0

null

[ "Francisellaceae" ]

[ 27 ]

1

[]

0

true

Family

FTL_1293 small RNA FtrC-regulated protein

FTL_1293-like

7

IPR061404

61,404

Motility-associated protein Scm1

Scm1

Family

27

false

Scm1 (Spiroplasma citri motility gene 1) was shown by loss-of-function mutation to be involved in motility. The Scm1 family is widespread in the genus Spiroplasma, members of the Mollicutes (bacteria with no cell wall) that have a spiral shape organized around a contractile ribbon fibril made of repeating subunits of t...

[]

0

[ "NCBIFAM" ]

[ "NF033571" ]

[ "motil_scm1_spiro" ]

[ 27 ]

1

[]

0

[]

0

[ "PUB00105182" ]

[ "9244268" ]

[ "Isolation, characterization, and complementation of a motility mutant of Spiroplasma citri." ]

[ 1997 ]

1

[]

0

null

[ "Spiroplasma" ]

[ 27 ]

1

[]

0

true

Family

Motility-associated protein Scm1

Scm1

8

IPR061405

61,405

Lp6.6 lipoprotein

Lipo_6_6

Family

27

false

In Borrelia burgdorferi, the tiny lipoprotein Lp6.6 is plasmid-borne and was originally described as a major low-molecular-weight lipoprotein that could constitute 2% of the dry weight of defatted cells. Lp6.6 was later found to facilitate transmission from ticks to mice, and to be down-regulated after infection.

[]

0

[ "NCBIFAM" ]

[ "NF033515" ]

[ "lipo_6_6_Borrel" ]

[ 27 ]

1

[]

0

[]

0

[ "PUB00105149", "PUB00105150", "PUB00105151" ]

[ "1452330", "19703109", "9009290" ]

[ "Purification and immunological characterization of a major low-molecular-weight lipoprotein from Borrelia burgdorferi.", "Borrelia burgdorferi small lipoprotein Lp6.6 is a member of multiple protein complexes in the outer membrane and facilitates pathogen transmission from ticks to mice.", "Molecular character...

[ 1992, 2009, 1997 ]

3

[]

0

null

[ "Borreliaceae" ]

[ 27 ]

1

[]

0

true

Family

Lp6.6 lipoprotein

Lipo_6_6

6

IPR061406

61,406

CotZ-related putative spore coat protein

CotZ-rel

Family

26

false

Members of this appear only in endospore-forming bacteria, and are distantly related to spore coat protein CotZ.

[]

0

[ "NCBIFAM" ]

[ "NF040827" ]

[ "CotZ_rel" ]

[ 26 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacillales" ]

[ 26 ]

1

[]

0

true

Family

CotZ-related putative spore coat protein

CotZ-rel

1

IPR061407

61,407

CDI system lipoprotein BcpO

BcpO

Family

25

false

BcpO is a small lipoprotein, about 74 amino acids long on average, encoded in Burkholderia bcpAIOB locus systems for two-partner secretion and contact dependent growth inhibition.

[]

0

[ "NCBIFAM" ]

[ "NF037971" ]

[ "lipo_BcpO" ]

[ 25 ]

1

[]

0

[]

0

[ "PUB00105492" ]

[ "22912595" ]

[ "The Burkholderia bcpAIOB genes define unique classes of two-partner secretion and contact dependent growth inhibition systems." ]

[ 2012 ]

1

[]

0

null

[ "Burkholderiaceae" ]

[ 25 ]

1

[]

0

true

Family

CDI system lipoprotein BcpO

BcpO

7

IPR061408

61,408

CNF1-like cytotoxic necrotizing factor

CNF1-like

Family

23

false

The CNF1 family of cytotoxic necrotizing factors are glutamine amidases that find their way to their eukaryotic host cells' cytosol and permanently activate certain GTPases. It includes full-length homologues of CNF1, CNF2, CNF3, and CNFY, but it excludes smaller proteins such as the type 3 secretion system effector Vo...

[]

0

[ "NCBIFAM" ]

[ "NF033651" ]

[ "cyto_nec_fctrs" ]

[ 23 ]

1

[]

0

[ "6yhk", "6yhl" ]

2

[]

0

[]

0

null

[ "Gammaproteobacteria" ]

[ 23 ]

1

[]

0

true

Family

CNF1-like cytotoxic necrotizing factor

CNF1-like

8

IPR061409

61,409

LifA/Efa1-related large cytotoxin

LifA/Efa1-rel_toxin

Family

23

false

Members of this family are large and almost certainly multifunctional proteins found in various pathogens from genus Chlamydia, about 3000 amino acids in size and related to lymphostatin (Efa1/LifA) from enteropathogenic Escherichia coli. Roles have been suggested for Efa1 (EHEC factor for adherence) in adhesion, so so...

[]

0

[ "NCBIFAM" ]

[ "NF033479" ]

[ "Efa1_rel_toxin" ]

[ 23 ]

1

[]

0

[]

0

[ "PUB00105128" ]

[ "11707582" ]

[ "Chlamydia trachomatis cytotoxicity associated with complete and partial cytotoxin genes." ]

[ 2001 ]

1

[]

0

null

[ "Chlamydia" ]

[ 23 ]

1

[]

0

true

Family

LifA/Efa1-related large cytotoxin

LifA/Efa1-rel_toxin

8

IPR061410

61,410

T9SS-dependent outer membrane TapA/TapC-like

TapA/TapC-like

Family

22

false

TapA (TprA-associated protein A, ) and TapC ( ), nearly tandem full-length homologues, are encoded in the oral pathogen Porphyromonas gingivalis next to the genes for TapB, and interact with the tetratricopeptide repeat protein TprA ( ). All four contribute to virulence. Full length close homologues of TapA and TapC ar...

[]

0

[ "NCBIFAM" ]

[ "NF050177" ]

[ "TapA_OM_Porphy" ]

[ 22 ]

1

[]

0

[]

0

[ "PUB00162725" ]

[ "20351137" ]

[ "Tetratricopeptide repeat protein-associated proteins contribute to the virulence of Porphyromonas gingivalis." ]

[ 2010 ]

1

[]

0

null

[ "Porphyromonas" ]

[ 22 ]

1

[]

0

true

Family

T9SS-dependent outer membrane TapA/TapC-like

TapA/TapC-like

2

IPR061411

61,411

NGO1622-like phage-associated putative holin

NGO1622-like

Family

22

false

Members of this family, including NGO1622 from Neisseria gonorrhoeae ( ), are phage region-encoded proteins strictly limited to Neisseria species. Members are suggested to act as holins, but the actual function has not yet been shown [ ].

[]

0

[ "NCBIFAM" ]

[ "NF046041" ]

[ "holin_NGO1622" ]

[ 22 ]

1

[]

0

[]

0

[ "PUB00106624" ]

[ "17615066" ]

[ "Characterization of the dsDNA prophage sequences in the genome of Neisseria gonorrhoeae and visualization of productive bacteriophage." ]

[ 2007 ]

1

[]

0

null

[ "Neisseria" ]

[ 22 ]

1

[]

0

true

Family

NGO1622-like phage-associated putative holin

NGO1622-like

8

IPR061412

61,412

MAG1680-like

Family

22

false

This protein family includes paralogous lipoproteins each in Mycoplasmopsis bovis and Mycoplasmopsis agalactiae, such as MAG1680 ( ). Members are homologous from end to end and average about 470 amino acids in length.

[]

0

[ "NCBIFAM" ]

[ "NF045878" ]

[ "Mbov_0186_LP" ]

[ 22 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Mycoplasmopsis" ]

[ 22 ]

1

[]

0

true

Family

MAG1680-like

6

IPR061414

61,414

Cell invasion LPXTG-type Vip

Vip_LPXTG

Family

19

false

Vip (Virulence protein), like the LPXTG-type internalins, is an LPXTG-anchored surface protein of the mammalian cell-invading pathogen Listeria monocytogenes, but absent from the related species Listeria innocua. For certain cell types, Vip is required for Listeria's ability to invade. It appears to bind the endoplasmi...

[]

0

[ "NCBIFAM" ]

[ "NF033201" ]

[ "Vip_LPXTG_Lm" ]

[ 19 ]

1

[]

0

[]

0

[ "PUB00105023" ]

[ "16015374" ]

[ "Gp96 is a receptor for a novel Listeria monocytogenes virulence factor, Vip, a surface protein." ]

[ 2005 ]

1

[]

0

null

[ "Listeria monocytogenes" ]

[ 19 ]

1

[]

0

true

Family

Cell invasion LPXTG-type Vip

Vip_LPXTG

6

IPR061415

61,415

MyrrNad domain

Myrrnad_dom

Domain

18

false

This entry (MyrrNad, MYcoplasma Repeat-Rich protein C-terminal Anchor Domain) represents the N-terminal domain counterpart to MyrrCad ( ), found in a family of LRR-like repeat proteins.

[]

0

[ "NCBIFAM" ]

[ "NF038275" ]

[ "Myrrnad" ]

[ 18 ]

1

[]

0

[]

0

[ "PUB00105691" ]

[ "28630471" ]

[ "Candidatus Mycoplasma girerdii replicates, diversifies, and co-occurs with Trichomonas vaginalis in the oral cavity of a premature infant." ]

[ 2017 ]

1

[]

0

null

[ "Candidatus Malacoplasma girerdii" ]

[ 18 ]

1

[]

0

true

Domain

MyrrNad domain

Myrrnad_dom

6

IPR061416

61,416

Serine-rich glycoprotein adhesin, prefix domain

SerRich_N

Domain

37

false

This entry represents a Limosilactobacillus-restricted N-terminal non-repetitive sequence region shared by proteins with extensive serine-rich repeat regions, all likely to function as adhesins. This region contains a variant form of the KxYKxGKxW motif ( ) followed by a region related to serine-rich glycoprotein adhes...

[]

0

[ "NCBIFAM" ]

[ "NF033676" ]

[ "Lacb_SerRich_Nt" ]

[ 37 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Limosilactobacillus" ]

[ 37 ]

1

[]

0

true

Domain

Serine-rich glycoprotein adhesin, prefix domain

SerRich_N

6

IPR061417

61,417

CDS14-like ICE transfer lipoprotein

ICE_LP_CDS14

Family

18

false

Integrative conjugative elements (ICE) in Mycoplasma-related wall-less bacteria undergo lateral gene transfer by mechanisms that require living donor and recipient cells. Members of this highly diverse family are large lipoproteins encoded in ICE loci. This entry includes CDS14 ( ), which was shown to be required to en...

[]

0

[ "NCBIFAM" ]

[ "NF045940" ]

[ "ICE_LP_CDS14" ]

[ 18 ]

1

[]

0

[]

0

[ "PUB00159792", "PUB00159793" ]

[ "29970462", "23888872" ]

[ "The Integrative Conjugative Element (ICE) of Mycoplasma agalactiae: Key Elements Involved in Horizontal Dissemination and Influence of Coresident ICEs.", "ICEA of Mycoplasma agalactiae: a new family of self-transmissible integrative elements that confers conjugative properties to the recipient strain." ]

[ 2018, 2013 ]

2

[]

0

null

[ "Mycoplasmatota" ]

[ 18 ]

1

[]

0

true

Family

CDS14-like ICE transfer lipoprotein

ICE_LP_CDS14

4

IPR061418

61,418

Type VI secretion system immunity protein TaeI-like

TaeI-like

Family

17

false

TaeI from Acinetobacter baumannii is an immunity protein for the anti-fungal type VI secretion system effector DNase TafE [ ].

[]

0

[ "NCBIFAM" ]

[ "NF041834" ]

[ "immunity_TaeI" ]

[ 17 ]

1

[]

0

[]

0

[ "PUB00152966" ]

[ "36625573" ]

[ "Acinetobacter baumannii Kills Fungi via a Type VI DNase Effector." ]

[ 2023 ]

1

[]

0

null

[ "Acinetobacter" ]

[ 17 ]

1

[]

0

true

Family

Type VI secretion system immunity protein TaeI-like

TaeI-like

7

IPR061419

61,419

MAG1890-like

Family

16

false

Members of this family are restricted to the Mycoplasmatota, and average about 325 amino acids in length, including MAG1890 from Mycoplasmopsis agalactiae ( ). An invariant Cys residue at position 32 suggests that members may be lipoproteins.

[]

0

[ "NCBIFAM" ]

[ "NF045970" ]

[ "MAG1890_fam_LP" ]

[ 16 ]

1

[]

0

[]

0

[ "PUB00159650" ]

[ "27765069" ]

[ "Genetic loci of Mycoplasma agalactiae involved in systemic spreading during experimental intramammary infection of sheep." ]

[ 2016 ]

1

[]

0

null

[ "Mycoplasmopsis" ]

[ 16 ]

1

[]

0

true

Family

MAG1890-like

2

IPR061420

61,420

Adhesion factor FAF

Adhesion_FAF

Family

16

false

FAF (Finegoldia adhesion factor) has firstly been characterised in the opportunistic pathogen Finegoldia magna. FAF mediate bacterial adhesion to hosts through interactions with the basement membrane protein BM-40 [ ].

[]

0

[ "NCBIFAM" ]

[ "NF040765" ]

[ "adhesion_FAF" ]

[ 16 ]

1

[]

0

[]

0

[ "PUB00105947" ]

[ "18808384" ]

[ "Identification of a novel protein promoting the colonization and survival of Finegoldia magna, a bacterial commensal and opportunistic pathogen." ]

[ 2008 ]

1

[]

0

null

[ "Finegoldia" ]

[ 16 ]

1

[]

0

true

Family

Adhesion factor FAF

Adhesion_FAF

6

IPR061421

61,421

CFI-box putative sorting motif

Sort_motif_CFI

Conserved_site

18

false

By several criteria, the motif represented by this entry seems likely to be a site of post-translational modification associated with protein-sorting and probably with attachment to the bacterial cell surface. Some members of have an extension with this motif while others do not. Some proteins in Desulfatibacillum alip...

[]

0

[ "NCBIFAM" ]

[ "NF041763" ]

[ "sort_motif_CFI" ]

[ 18 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "marine sediment metagenome" ]

[ 13, 4, 1 ]

3

[]

0

true

Conserved_site

CFI-box putative sorting motif

Sort_motif_CFI

5

IPR061422

61,422

Collagen-binding adhesin autotransporter EmaA

EmaA

Family

15

false

This protein family includes EmaA (extracellular matrix protein adhesin) from Aggregatibacter (Actinobacillus) actinomycetemcomitans, and related proteins from gammaproteobacteria. It is an outer membrane glycoprotein, and has a C-terminal β-barrel domain that marks it as an autotransporter. It serves as an adhesin tha...

[]

0

[ "NCBIFAM" ]

[ "NF033477" ]

[ "EmaA_autotrans" ]

[ 15 ]

1

[]

0

[]

0

[ "PUB00105123", "PUB00105124", "PUB00105125" ]

[ "15289564", "17660409", "22689812" ]

[ "Identification of an extracellular matrix protein adhesin, EmaA, which mediates the adhesion of Actinobacillus actinomycetemcomitans to collagen.", "Molecular heterogeneity of EmaA, an oligomeric autotransporter adhesin of Aggregatibacter (Actinobacillus) actinomycetemcomitans.", "O-polysaccharide glycosylatio...

[ 2004, 2007, 2012 ]

3

[]

0

null

[ "Aggregatibacter" ]

[ 15 ]

1

[]

0

true

Family

Collagen-binding adhesin autotransporter EmaA

EmaA

1

IPR061423

61,423

GEGP motif-containing diheme protein

Diheme_GEGP

Family

14

false

This uncharacterised protein family is named for a pair of heme-binding CXXCH motifs in the N-terminal region and a nearly invariant GEGP motif. All members have predicted N-terminal signal peptides.

[]

0

[ "NCBIFAM" ]

[ "NF041762" ]

[ "diheme_GEGP" ]

[ 14 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria" ]

[ 14 ]

1

[]

0

true

Family

GEGP motif-containing diheme protein

Diheme_GEGP

5

IPR061424

61,424

Autotransporter adhesin RadD

RadD

Family

15

false

This protein family includes RadD from Fusobacterium nucleatum and related sequences. RadD is named as an arginine (R)-inducible adhesin, and as the fourth gene (D) of a locus in which the other genes were designated radA, radB, and radC prior to characterisation. Full-length homologues from other species of Fusobacter...

[]

0

[ "NCBIFAM" ]

[ "NF049908" ]

[ "RadD_AT_adhesin" ]

[ 15 ]

1

[]

0

[]

0

[ "PUB00163126", "PUB00163127", "PUB00163128", "PUB00163129" ]

[ "19007407", "33227279", "39169124", "30986689" ]

[ "The Fusobacterium nucleatum outer membrane protein RadD is an arginine-inhibitable adhesin required for inter-species adherence and the structured architecture of multispecies biofilm.", "Fusobacteriumnucleatum Adheres to Clostridioides difficile via the RadD Adhesin to Enhance Biofilm Formation in Intestinal Mu...

[ 2009, 2021, 2024, 2019 ]

4

[]

0

null

[ "Fusobacterium" ]

[ 15 ]

1

[]

0

true

Family

Autotransporter adhesin RadD

RadD

8

IPR061425

61,425

AMEP412-like elicitor-associated permease-like

Elici_assc_perm

Family

13

false

Members of this family are found as part of a conserved bacterial gene neighbourhood, along with AMEP412 family proteins and an apparent ABC transporter ATP-binding protein. The hydrophobic nature of this protein suggests the protein is a transporter subunit associated with AMEP412 family protein export. Members of the...

[]

0

[ "NCBIFAM" ]

[ "NF040842" ]

[ "elici_assc_perm" ]

[ 13 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacillales" ]

[ 13 ]

1

[]

0

true

Family

AMEP412-like elicitor-associated permease-like

Elici_assc_perm

8

IPR061426

61,426

TrhA, N-terminal extension domain

TrhA_N

Domain

12

false

This rather rare domain appears as an occasional N-terminal extension to TrhA, or as a free-standing protein. TrhA (transmembrane homeostasis protein A), a plasma membrane protein that belongs to the PAQR family, named for eukaryotic Progestin and AdipoQ Receptors, and that appears involved in the homeostasis of membra...

[]

0

[ "NCBIFAM" ]

[ "NF047868" ]

[ "TrhA_N_extend" ]

[ 12 ]

1

[]

0

[]

0

[ "PUB00159123", "PUB00159124", "PUB00159125" ]

[ "35285724", "37345585", "38054739" ]

[ "Bacterial Homologs of Progestin and AdipoQ Receptors (PAQRs) Affect Membrane Energetics Homeostasis but Not Fluidity.", "PAQR proteins and the evolution of a superpower: Eating all kinds of fats: Animals rely on evolutionarily conserved membrane homeostasis proteins to compensate for dietary variation.", "TrhA...

[ 2022, 2023, 2024 ]

3

[]

0

null

[ "Bacteria", "mine drainage metagenome" ]

[ 11, 1 ]

2

[]

0

true

Domain

TrhA, N-terminal extension domain

TrhA_N

1

IPR061427

61,427

Myxosortase MrtZ

MrtZ

Family

10

false

MrtZ is a myxosortase, that is, an intramembrane glutamic endopeptidase for the MYXO-CTERM C-terminal protein-sorting signal. Members of this protein family are found in nannocystales.

[]

0

[ "NCBIFAM" ]

[ "NF040915" ]

[ "CPBP_fam_MrtZ" ]

[ 10 ]

1

[]

0

[]

0

[ "PUB00154714" ]

[ "38084967" ]

[ "In silico discovery of the myxosortases that process MYXO-CTERM and three novel prokaryotic C-terminal protein-sorting signals that share invariant Cys residues." ]

[ 2024 ]

1

[]

0

null

[ "Nannocystaceae" ]

[ 10 ]

1

[]

0

true

Family

Myxosortase MrtZ

MrtZ

8

IPR061429

61,429

EspK/GogB-like type III secretion system effector

EspK/GogB-like

Family

9

false

Members of this family, typically found in the genus Yersinia, are probably type III secretion system (T3SS) effectors homologous to the EspK from enterohaemorrhagic Escherichia coli (EHEC) and the anti-inflammatory effector GogB from Salmonella enterica [ , ].

[]

0

[ "NCBIFAM" ]

[ "NF011915" ]

[ "PRK15386.1-4" ]

[ 9 ]

1

[]

0

[]

0

[ "PUB00104989", "PUB00104990" ]

[ "16958848", "15843015" ]

[ "Identification and characterization of EspK, a type III secreted effector protein of enterohaemorrhagic Escherichia coli O157:H7.", "Genetic and molecular analysis of GogB, a phage-encoded type III-secreted substrate in Salmonella enterica serovar typhimurium with autonomous expression from its associated phage....

[ 2006, 2005 ]

2

[]

0

null

[ "Yersinia pseudotuberculosis complex" ]

[ 9 ]

1

[]

0

true

Family

EspK/GogB-like type III secretion system effector

EspK/GogB-like

7

IPR061430

61,430

Collagen-binding adhesin Cbm, N-terminal domain

Cbm_N

Domain

9

false

This entry represents the non-repetitive region of the collagen-binding adhesin Cbm from the N terminus to just before the start of the glycosylated Thr-rich repeat region. The length of the repeat region is highly variable. Cbm is found in a minority of strains of the dental caries-causing oral pathogen Streptococcus ...

[]

0

[ "NCBIFAM" ]

[ "NF050823" ]

[ "collag_bnd_Cbm" ]

[ 9 ]

1

[]

0

[]

0

[ "PUB00162714", "PUB00162715", "PUB00162716" ]

[ "22759315", "29524318", "32002675" ]

[ "Identification and characterization of a collagen-binding protein, Cbm, in Streptococcus mutans.", "Whole genome sequence and phenotypic characterization of a Cbm+ serotype e strain of Streptococcus mutans.", "Association of Streptococcus mutans collagen binding genes with severe childhood caries." ...

[ 2012, 2018, 2020 ]

3

[]

0

null

[ "Streptococcus mutans" ]

[ 9 ]

1

[]

0

true

Domain

Collagen-binding adhesin Cbm, N-terminal domain

Cbm_N

3

IPR061432

61,432

Trimeric autotransporter actin-nucleating factor BimA

BimA

Family

8

false

This entry represents BimA (Burkholderia intracellular motility A, ) and similar proteins in Burkholderia mallei or B. pseudomallei.

[]

0

[ "NCBIFAM" ]

[ "NF040983" ]

[ "BimA_second" ]

[ 8 ]

1

[]

0

[]

0

[ "PUB00106113", "PUB00106114" ]

[ "16267310", "21811486" ]

[ "Actin-binding proteins from Burkholderia mallei and Burkholderia thailandensis can functionally compensate for the actin-based motility defect of a Burkholderia pseudomallei bimA mutant.", "Autotransporters and Their Role in the Virulence of Burkholderia pseudomallei and Burkholderia mallei." ]

[ 2005, 2011 ]

2

[]

0

null

[ "pseudomallei group" ]

[ 8 ]

1

[]

0

true

Family

Trimeric autotransporter actin-nucleating factor BimA

BimA

7

IPR061433

61,433

Transglutaminase-like, putative

Transglutaminase-like_put

Family

8

false

Members of this family are thought to belong to the transglutaminase-like superfamily. The function of this family of large proteins (about 650 amino acids long) remains unknown.

[]

0

[ "NCBIFAM" ]

[ "NF045997" ]

[ "Mbov0119_fam" ]

[ 8 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Mycoplasmatota" ]

[ 8 ]

1

[]

0

true

Family

Transglutaminase-like, putative

Transglutaminase-like_put

4

IPR061434

61,434

Omp28-related selenoprotein

Omp28-rel_seleno

Family

17

false

Members of this family are selenoproteins distantly related to the Porphyromonas gingivalis protein named Omp28 ( ). A selenocysteine-containing motif UPYCP aligns to CLYCP in Omp28. Members have been found, so far, primarily in Candidatus Marinimicrobia species. Some members of this family have a long C-terminal exten...

[]

0

[ "NCBIFAM" ]

[ "NF045500" ]

[ "Omp28_seleno" ]

[ 17 ]

1

[]

0

[]

0

[ "PUB00053486", "PUB00106154" ]

[ "12030966", "35883471" ]

[ "Characterization and expression of a novel Porphyromonas gingivalis outer membrane protein, Omp28.", "Selenium Metabolism and Selenoproteins in Prokaryotes: A Bioinformatics Perspective." ]

[ 2002, 2022 ]

2

[]

0

null

[ "marine metagenome" ]

[ 17 ]

1

[]

0

true

Family

Omp28-related selenoprotein

Omp28-rel_seleno

1

IPR061435

61,435

Colicin Z toxin

Colicin_Z

Family

7

false

This entry represents full-length homologues of the colicin Z activity protein [ ]. The C-terminal domain is found more broadly, and is described by .

[]

0

[ "NCBIFAM" ]

[ "NF041263" ]

[ "colicin_Z_full" ]

[ 7 ]

1

[]

0

[]

0

[ "PUB00106274" ]

[ "31366939" ]

[ "Colicin Z, a structurally and functionally novel colicin type that selectively kills enteroinvasive Escherichia coli and Shigella strains." ]

[ 2019 ]

1

[]

0

null

[ "Enterobacterales" ]

[ 7 ]

1

[]

0

true

Family

Colicin Z toxin

Colicin_Z

1

IPR061436

61,436

PLuB system helicase-like

PLuB_helicase-like

Family

7

false

The PLuB system is found in deltaproteobacteria. Proteins in this entry, with an AAA+ domain, shows strong local homology to various helicases. The system also includes a CPBP family intramembrane glutamic endopeptidase and a PQQ-binding-like β-propeller repeat protein.

[]

0

[ "NCBIFAM" ]

[ "NF040671" ]

[ "PLuB_AAA" ]

[ 7 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bradymonadales" ]

[ 7 ]

1

[]

0

true

Family

PLuB system helicase-like

PLuB_helicase-like

4

IPR061437

61,437

Type III-I CRISPR-associated gRAMP effector Cas7-11i

Cas_III-I_gRAMP

Family

6

false

The giant RAMP (gRAMP) effector of type III-E CRISPR/Cas systems is named Cas7-11 because of its multiple domain structure includes a Cas7 and a Cas11-like region.

[]

0

[ "NCBIFAM" ]

[ "NF049957" ]

[ "Cas_III-I_gRAMP" ]

[ 6 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria" ]

[ 6 ]

1

[]

0

true

Family

Type III-I CRISPR-associated gRAMP effector Cas7-11i

Cas_III-I_gRAMP

5

IPR061438

61,438

Type III-E CRISPR-associated protein Csx30

CAS_csx30

Family

6

false

Csx30, encoded in type III-E CRISPR systems, was identified as the proteolytic target of craspase (CRISPR-guided caspase), which is a complex of the gRAMP (giant RAMP) protein Cas7-11 and the TPR-CHAT protein Csx29 [ ].

[]

0

[ "NCBIFAM" ]

[ "NF041234" ]

[ "CAS_csx30" ]

[ 6 ]

1

[]

0

[ "8eey" ]

1

[ "PUB00106253" ]

[ "36007061" ]

[ "Craspase is a CRISPR RNA-guided, RNA-activated protease." ]

[ 2022 ]

1

[]

0

null

[ "Pseudomonadati" ]

[ 6 ]

1

[]

0

true

Family

Type III-E CRISPR-associated protein Csx30

CAS_csx30

2

IPR061439

61,439

PARCEL repeat surface lipoprotein Mbov_0838-like

Mbov_0838-like

Family

6

false

This protein family represents one of several surface lipoproteins that are paralogous in the cattle pathogen Mycoplasmopsis bovis, including Mbov_0838 ( ). Members average over 400 amino acids in length, and contain a 100 amino acid region with (mostly weak) PARCEL tandem repeats ( ).

[]

0

[ "NCBIFAM" ]

[ "NF045896" ]

[ "Mbov_0838_LP" ]

[ 6 ]

1

[]

0

[]

0

[ "PUB00159277", "PUB00159673" ]

[ "20626840", "21134966" ]

[ "A versatile palindromic amphipathic repeat coding sequence horizontally distributed among diverse bacterial and eucaryotic microbes.", "Complete genome sequence of Mycoplasma bovis type strain PG45 (ATCC 25523)." ]

[ 2010, 2011 ]

2

[]

0

null

[ "Mycoplasmopsis bovis" ]

[ 6 ]

1

[]

0

true

Family

PARCEL repeat surface lipoprotein Mbov_0838-like

Mbov_0838-like

3

IPR061440

61,440

Type III-E CRISPR-associated TPR-CHAT protein Csx29

CAS_csx29_CRASP

Family

5

false

Csx29, the protease subunit of the craspase complex, is a TPR-CHAP family protein of type III-E CRISPR/Cas systems. Craspase is guided by crRNA, but cleaves protein, not nucleotide, and therefore is highly interesting for potential technological applications [ , ].

[]

0

[ "NCBIFAM" ]

[ "NF041237" ]

[ "CAS_csx29_CRASP" ]

[ 5 ]

1

[]

0

[ "7x8a", "7xc7", "7xsq", "7xsr", "7xss", "7xt4", "7y83", "7y84", "7y85", "7y8t", "7y8y", "7y9x", "7y9y", "7ynd", "7zoq", "8d9f", "8d9g", "8d9h", "8eex", "8eey", "8gs2", "8gu6", "8wmc" ]

23

[ "PUB00105607", "PUB00106253" ]

[ "31857715", "36007061" ]

[ "Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.", "Craspase is a CRISPR RNA-guided, RNA-activated protease." ]

[ 2020, 2022 ]

2

[]

0

null

[ "Pseudomonadati" ]

[ 5 ]

1

[]

0

true

Family

Type III-E CRISPR-associated TPR-CHAT protein Csx29

CAS_csx29_CRASP

5

IPR061441

61,441

Type III-E CRISPR-associated gRAMP effector Cas7-11e

Cas_III-E_gRAMP

Family

5

false

The giant RAMP (gRAMP) effector of type III-E CRISPR/Cas systems, named Cas7-11 because of its multiple domains, works together with the caspase-like TPR-CHAT protease (Csx29) in a subset of type III-E systems. The complex of the Cas7-11 and the TPR-CHAT subunits is called craspase (CRISPR-guided caspase) [ , , ].

[]

0

[ "NCBIFAM" ]

[ "NF041225" ]

[ "Cas_III-E_gRAMP" ]

[ 5 ]

1

[]

0

[ "7wah", "7x7a", "7x7r", "7x8a", "7xc7", "7xso", "7xsp", "7xsq", "7xsr", "7xss", "7xt4", "7y80", "7y81", "7y82", "7y83", "7y84", "7y85", "7y8t", "7y8y", "7y9x", "7y9y", "7yn9", "7yna", "7ynb", "7ync", "7ynd", "7zol", "7zoq", "8d1v", "8d8n", "8d97", "8d9e"...

45

[ "PUB00105607", "PUB00106252", "PUB00106253" ]

[ "31857715", "35643083", "36007061" ]

[ "Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.", "Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex.", "Craspase is a CRISPR RNA-guided, RNA-activated protease." ]

[ 2020, 2022, 2022 ]

3

[]

0

null

[ "Pseudomonadati" ]

[ 5 ]

1

[]

0

true

Family

Type III-E CRISPR-associated gRAMP effector Cas7-11e

Cas_III-E_gRAMP

4

IPR061443

61,443

Exosortase XrtG-like, N-terminal extension domain

XrtG_Nterm_ext

Domain

3

false

This domain appears as an N-terminal extension, or an accompanying protein, for a minority of exosortase XrtG family putative protein-sorting intramembrane endopeptidases.

[]

0

[ "NCBIFAM" ]

[ "NF045489" ]

[ "XrtG_Nterm_ext" ]

[ 3 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Lactobacillus" ]

[ 3 ]

1

[]

0

true

Domain

Exosortase XrtG-like, N-terminal extension domain

XrtG_Nterm_ext

3

IPR061445

61,445

Triculamin-like lasso peptide precursor

Triculamin_precursor

Family

3

false

Triculamin and lariocidin are very similar naturally occurring peptide antibiotics derived by post-translational modification of ribosomally synthesised precursor peptides. They differ four positions in a core (mature) peptide length of 17. However, the precursor peptide architectures differ substantially, with the cor...

[]

0

[ "NCBIFAM" ]

[ "NF050031" ]

[ "triculamin_pre" ]

[ 3 ]

1

[]

0

[]

0

[ "PUB00162851", "PUB00162852", "PUB00162853" ]

[ "35748039", "6072424", "39977644" ]

[ "Triculamin: An Unusual Lasso Peptide with Potent Antimycobacterial Activity.", "Triculamin, a new antituberculosis substance.", "Evolution-Guided Discovery of Antimycobacterial Triculamin-Like Lasso Peptides." ]

[ 2022, 1967, 2025 ]

3

[]

0

null

[ "Streptomyces" ]

[ 3 ]

1

[]

0

true

Family

Triculamin-like lasso peptide precursor

Triculamin_precursor

3

IPR061446

61,446

LPXTG-anchored fibronectin-binding protein FbpA

FbpA

Family

2

false

FbpA, a fibronectin-binding protein described in Streptococcus pyogenes, has a YSIRK-type (crosswall-targeting) signal peptide and a C-terminal LPXTG motif for covalent attachment to the cell wall [ ]. It is unrelated to the PavA-like protein from Streptococcus gordonii that was given the identical name, so the phase L...

[]

0

[ "NCBIFAM" ]

[ "NF033913" ]

[ "fibronec_FbpA" ]

[ 2 ]

1

[]

0

[]

0

[ "PUB00105423" ]

[ "28808160" ]

[ "Incremental Contributions of FbaA and Other Impetigo-Associated Surface Proteins to Fitness and Virulence of a Classical Group A Streptococcal Skin Strain." ]

[ 2017 ]

1

[]

0

null

[ "Streptococcus pyogenes" ]

[ 2 ]

1

[]

0

true

Family

LPXTG-anchored fibronectin-binding protein FbpA

FbpA

9

IPR061447

61,447

PorH-like

Family

2

false

Proteins of this family form major outer membrane hetero-oligomeric pores on the cell wall of Corynebacterium with PorA porins [ ].

[]

0

[ "NCBIFAM" ]

[ "NF033937" ]

[ "porH_1" ]

[ 2 ]

1

[]

0

[]

0

[ "PUB00105442" ]

[ "19966008" ]

[ "Reconstitution experiments and gene deletions reveal the existence of two-component major cell wall channels in the genus Corynebacterium." ]

[ 2010 ]

1

[]

0

null

[ "Corynebacterium diphtheriae" ]

[ 2 ]

1

[]

0

true

Family

PorH-like

5

IPR061450

61,450

MFS transporter auxiliary subunit, OFA tail-like domain

MFS_OXA_tail_dom

Domain

2,992

false

This entry represents a domain that covers the whole length of the protein in a group of small, hydrophobic bacterial proteins that typically occur next to a much larger MFS (major facilitator superfamily) transporter. In some members of this group, this region occurs as a C-terminal extension domain to MFS transporter...

[]

0

[ "NCBIFAM" ]

[ "NF047966" ]

[ "MFS_OXA_tail_dom" ]

[ 2992 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Opisthokonta", "unclassified sequences" ]

[ 2972, 2, 18 ]

3

[]

0

true

Domain

MFS transporter auxiliary subunit, OFA tail-like domain

MFS_OXA_tail_dom

5

IPR061451

61,451

Major curlin subunit, enterobacterales

CsgA_enterobact

Family

588

false

Curli is a type of pilin characterised by export of unfolded structural subunits and then amyloid-type self-assembly into fibres. This entry represents CsgA, the major subunit of the type of curli fibres found in E.coli and other enterobacterales. Translocation of CsgA is by the Sec system through the inner membrane, a...

[]

0

[ "NCBIFAM" ]

[ "NF007470" ]

[ "PRK10051.1" ]

[ 588 ]

1

[ "REACTOME" ]

[ "R-HSA-9638630" ]

[ "REACTOME:R-HSA-9638630" ]

1

[ "8enq", "8enr" ]

2

[ "PUB00027885", "PUB00104532" ]

[ "9457880", "28496159" ]

[ "Curli fibers are highly conserved between Salmonella typhimurium and Escherichia coli with respect to operon structure and regulation.", "A comprehensive guide to pilus biogenesis in Gram-negative bacteria." ]

[ 1998, 2017 ]

2

[]

0

null

[ "Gammaproteobacteria", "Opisthokonta" ]

[ 585, 3 ]

2

[ "Escherichia coli (strain K12)" ]

[ 2 ]

1

true

Family

Major curlin subunit, enterobacterales

CsgA_enterobact

8

IPR061452

61,452

Secreted effector protein SptP

SptP

Family

563

false

This entry represents a family of proteins from Sallmonella species, including Secreted effector protein SptP, which facilitates bacterial survival in host cells and includes tyrosine phosphatase and GTPase activating protein (GAP) activities [ , , ].

[]

0

[ "NCBIFAM" ]

[ "NF011902" ]

[ "PRK15375.1" ]

[ 563 ]

1

[ "EC" ]

[ "3.1.3.48" ]

[ "EC:3.1.3.48" ]

1

[]

0

[ "PUB00006663", "PUB00006683", "PUB00021650" ]

[ "8866485", "10499590", "11163217" ]

[ "A secreted protein tyrosine phosphatase with modular effector domains in the bacterial pathogen Salmonella typhimurium.", "A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.", "Modulation of host signaling by a bacterial mimic: structure of the Salmonella e...

[ 1996, 1999, 2000 ]

3

[]

0

null

[ "Salmonella" ]

[ 563 ]

1

[]

0

true

Family

Secreted effector protein SptP

SptP

2

IPR061453

61,453

Choice-of-anchor X domain

Choice_anch_X_dom

Domain

2,940

false

This entry represents a domain mainly found in a group of eukaryotic Calcium-activated chloride channel regulators and prokaryotic proteins with C-terminal sorting signals for processing by rhombosortases and myxosortases and eventual surface attachment.

[]

0

[ "NCBIFAM" ]

[ "NF041940" ]

[ "choice_anch_X" ]

[ 2940 ]

1

[ "REACTOME", "REACTOME" ]

[ "R-HSA-2672351", "R-MMU-2672351" ]

[ "REACTOME:R-HSA-2672351", "REACTOME:R-MMU-2672351" ]

2

[]

0

[]

0

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 43, 1070, 1777, 50 ]

4

[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 3, 5, 12, 6 ]

4

true

Domain

Choice-of-anchor X domain

Choice_anch_X_dom

8

IPR061454

61,454

Flocculation-associated PEP-CTERM protein PepA-like

PepA-like

Family

247

false

PepA was described in Zoogloea resiniphila as a PEP-CTERM protein regulated by the PrsK/PrsR two-component system. Knocking out that system blocks flocculation, after which expression of recombinant PepA can restore flocculation [ ]. This entry represents a group of PEP-CTERM-containing proteins from proteobacteria, in...

[]

0

[ "NCBIFAM" ]

[ "NF033554" ]

[ "floc_PepA" ]

[ 247 ]

1

[]

0

[]

0

[ "PUB00105164", "PUB00152935" ]

[ "29473278", "36658495" ]

[ "Both widespread PEP-CTERM proteins and exopolysaccharides are required for floc formation of Zoogloea resiniphila and other activated sludge bacteria.", "An RpoN-dependent PEP-CTERM gene is involved in floc formation of an Aquincola tertiaricarbonis strain." ]

[ 2018, 2023 ]

2

[]

0

null

[ "Bacteria", "bioreactor metagenome" ]

[ 246, 1 ]

2

[]

0

true

Family

Flocculation-associated PEP-CTERM protein PepA-like

PepA-like

2