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help me improve hydrogen bond acceptors and H-bond donors of molecule CCOc1c(Cl)cccc1CC(=O)N1Cc2ccccc2OC[C@H]1C.
CCOc1c(CC(=O)N2Cc3ccccc3OC[C@H]2C)cccc1C(=NN)NN
Help me reduce the number of hydrogen bond donors in molecule Cc1cccc(Cn2c(=O)c(C(=O)NCN)nn(-c3ccc(F)cc3)c2=O)c1
Cc1cccc(Cn2c(=O)c(C(=O)Nc3ccccc3)nn(-c3ccc(F)cc3)c2=O)c1
Help me reduce the number of hydrogen bond donors in molecule Cc1nc(C[NH+]2CCC(C(=O)NCCC(C)O)CC2)cs1
CCC(C)(C)C(C)CCNC(=O)C1CC[NH+](Cc2csc(C)n2)CC1
help me reduce H-bond donors and improve QED score of molecule NC(=[NH2+])c1nc[nH]c1C(=O)N[C@@H]1CCN([C@H]2CCNC2=O)C1.
Cc1nc[nH]c1C(=O)N[C@@H]1CCN([C@H]2CCNC2=O)C1
Help me make the molecule COCCN1CC[C@H](NC(=O)Cn2ccnc2C)[C@H](C(C)=CCCBr)C1 with more hydrogen bond donors
COCCN1CC[C@H](NC(=O)Cn2ccnc2C)[C@H](O)C1
Help me reduce the QED of molecule COc1cc(F)cc(CNc2ccc(S[C@@H](C)C(=O)O)cc2)c1 to make it less like a drug
CC(C)c1cccc(Oc2cc(F)cc(CNc3ccc(S[C@@H](C)C(=O)O)cc3)c2)c1
Help me reduce the number of hydrogen bond donors in molecule C=CC(=CC(=CC)c1ccc(NC)c(C(=C)c2nc3c(-c4ccsc4)cncc3[nH]2)c1)N(C)C
C=CC(=CC(=CC)c1ccc(-c2ccc(C(C)(C)C)cc2)c(C(=C)c2nc3c(-c4ccsc4)cncc3[nH]2)c1)N(C)C
Help me make the molecule O=C(c1ccc(F)c(F)c1Nc1ccc(I)cc1F)N1CC(C2CCC(CCCC3CCCC3)CC2)C1 with more hydrogen bond acceptors
O=C(c1ccc(F)c(F)c1Nc1ccc(I)cc1F)N1CC(NCC2CCCC2)C1
help me improve hydrogen bond acceptors and H-bond donors of molecule CCS(=O)(=O)N(CC(F)F)c1sc2ccccc2c1C.
CCS(=O)(=O)N(CC(F)F)c1sc2ccccc2c1B(O)O
help me reduce hydrogen bond acceptors and H-bond donors of molecule O=S(=O)(Nc1cccc(-c2cn3c(B(O)O)csc3n2)c1)c1ccccc1F.
Cc1csc2nc(-c3cccc(NS(=O)(=O)c4ccccc4F)c3)cn12
help me reduce H-bond donors and improve LogP value of molecule C[C@@H](CCNC(=O)C1CCC(C)(C)CC1)NC(=O)CCC(F)NC(=O)C(=O)NN.
C[C@@H](CCNC(=O)C1CCC(C)(C)CC1)NC(=O)CCC(F)F
help me reduce H-bond donors and improve LogP value of molecule C=C(Cl)CN[C@H]1C[C@H]2CC[C@H]1N(C(=O)c1c(B(O)O)coc1C)C2.
C=C(Cl)CN[C@H]1C[C@H]2CC[C@H]1N(C(=O)c1c(C)coc1C)C2
help me reduce hydrogen bond acceptors and H-bond donors of molecule O=C(Nc1ccc(B(O)O)c(S(=O)(=O)N2CCOCC2)c1)C(c1ccccc1)[NH+]1CCCC1.
Cc1ccc(NC(=O)C(c2ccccc2)[NH+]2CCCC2)cc1S(=O)(=O)N1CCOCC1
Help me reduce the number of hydrogen bond acceptors in molecule O=C1CCCN1N1CCC(COC(CO)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)CC1
C=C(CC(OCC1(c2ccccc2)CCN(N2CCCC2=O)CC1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1
Help me make the molecule C[C@H](NC(=O)CCc1cncs1)[C@@H](C)Nc1nc2ccccc2o1 with more hydrogen bond acceptors
CCC(CC)(CC)SC(NC(=O)CCc1cncs1)[C@@H](C)Nc1nc2ccccc2o1
help me reduce hydrogen bond acceptors and H-bond donors of molecule CCC(=O)Nc1ccc(C(=O)NCCNS(=O)(=O)c2ccc(OC)c(B(O)O)c2)cc1.
CCC(=O)Nc1ccc(C(=O)NCCNS(=O)(=O)c2ccc(OC)c(C)c2)cc1
Help me reduce the number of hydrogen bond acceptors in molecule CC(C)(C#N)c1cccc(C(=O)N(c2cncc(N(Cl)c3cc(Br)cn3C3CC3)c2)c2ccccc2C(N)=O)c1Cl
CN(Cl)c1cncc(N(C(=O)c2cccc(C(C)(C)C#N)c2Cl)c2ccccc2C(N)=O)c1
Help me make the molecule COc1cccc2c(=O)c(C(=O)Nc3nc(-c4ccc(Cl)cc4)cs3)c[nH]c12 with more hydrogen bond acceptors
O=C(Nc1nc(-c2ccc(Cl)cc2)cs1)c1c[nH]c2c(Oc3cc(Br)cn3C3CC3)cccc2c1=O
help me improve hydrogen bond acceptors and H-bond donors of molecule CCNC(=NCc1ccc(C)cc1OCC)NCC1(C)COC1.
CCNC(=NCc1ccc(B(O)O)cc1OCC)NCC1(C)COC1
Help me improve the QED of molecule CCCC(CCBr)C[C@@H](CNC(=O)[C@@H](C)Cc1ccc(C)cc1)N(C)Cc1nccs1 to make it more like a drug
Cc1ccc(C[C@H](C)C(=O)NC[C@H](C)N(C)Cc2nccs2)cc1
help me reduce LogP value and improve hydrogen bond acceptors and H-bond donors of molecule CC(C)(C)OC(=O)N[C@H](C(=O)N1CC[C@H]2CO[C@@H](CNC(=O)CCc3cn[nH]c3)[C@H]2C1)C1CC1.
CC(C)(C)OC(=O)NC(NC(=O)C(=O)N1CC[C@H]2CO[C@@H](CNC(=O)CCc3cn[nH]c3)[C@H]2C1)C(N)=O
Help me improve the QED of molecule CCC(NC(C)c1nc2sc3c(c2c(=O)[nH]1)CCC(C)C3)c1ccc(-c2csc(C(C)Cl)c2Cl)cc1 to make it more like a drug
CCC(NC(C)c1nc2sc3c(c2c(=O)[nH]1)CCC(C)C3)c1ccc(OC)cc1
help me reduce LogP value and QED score of molecule NS(=O)(=O)c1ccc(CNc2nc(C(F)(F)F)cc(=O)[nH]2)cc1.
NNC(=O)C(=O)NC(F)(F)c1cc(=O)[nH]c(NCc2ccc(S(N)(=O)=O)cc2)n1
help me improve hydrogen bond acceptors and H-bond donors of molecule CC(C)=CCCC1(C)C(CC=C(C)C)CC2(C)C(=O)C1(C(=O)c1ccccc1)C(=O)C1=C2OC(C(C)(C)O)C1O.
CC(=O)NCC(=O)NCC1(C)C(CC=C(C)C)CC2(C)C(=O)C1(C(=O)c1ccccc1)C(=O)C1=C2OC(C(C)(C)O)C1O
help me reduce LogP value and improve H-bond donors of molecule CC(=O)N1CCN(CC(=O)c2ccc3c(c2)OCCO3)CC1.
NC(=[NH2+])C(=O)N1CCN(CC(=O)c2ccc3c(c2)OCCO3)CC1
help me reduce LogP value and improve hydrogen bond acceptors of molecule Cc1cccc(-n2nc3c(c2NC(=O)c2cccs2)CS(=O)C3)c1C.
Cc1c(B(O)O)cccc1-n1nc2c(c1NC(=O)c1cccs1)CS(=O)C2
help me improve hydrogen bond acceptors and H-bond donors of molecule Cc1coc(C)c1C(=O)N[C@H]1CCC[C@@H](NC(=O)OC(C)(C)C)C1.
Cc1coc(B(O)O)c1C(=O)N[C@H]1CCC[C@@H](NC(=O)OC(C)(C)C)C1
Help me make the molecule CCOC(=O)N[C@H](O)C(=O)N1CCCC[C@@H]1C1CCN(C(=O)[C@H]2CCc3ccccc3O2)CC1 with more hydrogen bond acceptors
C=CC(=CC=CO)OC(C(=O)N1CCCC[C@@H]1C1CCN(C(=O)[C@H]2CCc3ccccc3O2)CC1)C(C)NC(=O)OCC
Help me reduce the QED of molecule CCCCC(=O)N[C@@]1(C)CCN(C(=O)C2(c3ccccc3C)CC2)C1 to make it less like a drug
CCCCC(=O)N[C@@]1(C)CCN(C(=O)C2(c3ccccc3-c3ccc(Cl)c(Cl)c3)CC2)C1
Help me make the molecule CSCC[C@@H](O)C(=O)N1CCCC12CN(C(=O)[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@@H]1F)C2 with more hydrogen bond acceptors
CC(C)(C)OC(=O)N1CC[C@@H](C(=O)N2CC3(CCCN3C(=O)[C@H](O)CCSSc3cccc(Cl)c3)C2)[C@@H](F)C1
Help me reduce the QED of molecule Cc1ccc([C@@H](C)N(C)C(=S)N[C@@H]2CCOc3ccccc32)cc1 to make it less like a drug
CCCCCCCCN(C(=S)N[C@@H]1CCOc2ccccc21)[C@H](C)c1ccc(C)cc1
help me improve hydrogen bond acceptors and H-bond donors of molecule Clc1ccn2ncc(CN3CCC[C@H](c4ccccn4)C3)c2n1.
NN=C(NN)c1ccn2ncc(CN3CCC[C@H](c4ccccn4)C3)c2n1
Help me make the molecule C=C(C=CC(=CC)c1c(OC)cc(Cn2c([C@H](C)NS(C)(=O)=O)nnc2N2CC[C@H](C)C2)cc1OC)C(C)CC with more hydrogen bond acceptors
COc1cc(Cn2c([C@H](C)NS(C)(=O)=O)nnc2N2CC[C@H](C)C2)cc(OC)c1OC
Help me make the molecule Cc1nc2cc(OCc3ccc(F)cc3)ccc2cc1C(=O)O with more hydrogen bond donors
O=C(O)c1cc2ccc(OCc3ccc(F)cc3)cc2nc1B(O)O
Help me reduce the QED of molecule COc1cc(N2C[C@H](C(=O)O[C@H]3CCC[C@@H](C#N)C3)CC2=O)cc(OC)c1OC to make it less like a drug
C=C[C@@H](CCCCCCC)Oc1cc(N2C[C@H](C(=O)O[C@H]3CCC[C@@H](C#N)C3)CC2=O)cc(OC)c1OC
Help me reduce the number of hydrogen bond acceptors in molecule CN(C)CC(C)(C)CNC(=O)C1CCN(C(=O)COc2cccc(NC(=O)c3ccco3)c2)CC1
CC(C)C(C)C(C)CCC(C)(C)CNC(=O)C1CCN(C(=O)COc2cccc(NC(=O)c3ccco3)c2)CC1
Help me make the molecule Cc1nsc(N2CC[C@@H](NC(=O)c3ccccc3CC(C)C)C2)n1 with more hydrogen bond donors
CC(C)Cc1ccccc1C(=O)N[C@@H]1CCN(c2nc(B(O)O)ns2)C1
help me improve hydrogen bond acceptors and H-bond donors of molecule CC(C)NC(N)=NCc1cc([N+](=O)[O-])cc(C(F)(F)F)c1.
CC(C)NC(N)=NCc1cc([N+](=O)[O-])cc(C(F)(F)NC(=O)C(=O)NN)c1
help me reduce LogP value and QED score of molecule CCO[C@H](CC)C(=O)N[C@H](C)CN(C)C(=O)c1ccsc1.
CCO[C@H](CC)C(=O)N[C@@H](CN(C)C(=O)c1ccsc1)C(N)=[NH2+]
Help me reduce the number of hydrogen bond acceptors in molecule C[C@@H](C[C@@H](C)CS(=O)(=O)NN(C)C)N[C@@H](C)c1nnc2ccccn12
CC(C)C[C@H](C)C[C@H](C)N[C@@H](C)c1nnc2ccccn12
Help me make the molecule COc1cc(C)cc(-c2noc([C@@H](NC(=O)c3ccccc3)C(C)C)n2)c1 with more hydrogen bond acceptors
CNCCNS(=O)(=O)[C@H](NC(=O)c1ccccc1)c1nc(-c2cc(C)cc(OC)c2)no1
Help me reduce the number of hydrogen bond donors in molecule C[C@@H](O)CN1CC[C@@H](NC(=O)c2cn(C)c(B(O)O)cc2=O)C1
Cc1cc(=O)c(C(=O)N[C@@H]2CCN(C[C@@H](C)O)C2)cn1C
help me reduce LogP value and improve H-bond donors of molecule CC(C)(C)OC(=O)N1CCC(N(C(=O)c2ccc(-c3ccc(C(N)=O)cc3)cc2)C2CC2)CC1.
CC(C)(C)OC(=O)N1CCC(N(C(=O)c2cc(C(N)=[NH+]O)ccc2-c2ccc(C(N)=O)cc2)C2CC2)CC1
Help me reduce the number of hydrogen bond donors in molecule CCCCCC(Cc1nc(-c2cccc(O)n2)no1)C(N)=[NH2+]
CCCCC[C@@H](C)Cc1nc(-c2cccc(O)n2)no1
help me reduce QED score and improve hydrogen bond acceptors of molecule CCN(CCCF)[C@H](C)CNC(=O)c1nc2c(s1)CCC2.
CCN(CCCNC(=O)C(=O)NN)[C@H](C)CNC(=O)c1nc2c(s1)CCC2
Help me reduce the QED of molecule NCC1CCC(n2cnc3cnc4c(ccn4S(=O)(=O)c4ccccc4)c32)CC1 to make it less like a drug
CC(NCC1CCC(n2cnc3cnc4c(ccn4S(=O)(=O)c4ccccc4)c32)CC1)c1ccc(Cl)cc1
Help me improve the QED of molecule CCOc1ccccc1OCCn1c(=O)[nH]c2sc(C(N)=[NH2+])cc2c1=O to make it more like a drug
CCOc1ccccc1OCCn1c(=O)[nH]c2sc(C)cc2c1=O
Help me make the molecule CCC(CC)CC(C)CCC(=O)c1cc2cc(-c3ccnc(C(=O)CCc4ccncc4)c3)ccc2[nH]1 with more hydrogen bond acceptors
COCC(=O)c1cc2cc(-c3ccnc(C(=O)CCc4ccncc4)c3)ccc2[nH]1
Help me reduce the number of hydrogen bond donors in molecule CCOC(=O)C(CCC(=O)O)NC(=O)C(N)Cc1ccccc1
CCOC(=O)C(CCC(=O)O)NC(=O)C(CC(F)=C(F)F)Cc1ccccc1
help me improve hydrogen bond acceptors and H-bond donors of molecule Cc1cc(N)cc(C)c1S(=O)(=O)NCCC(C)S(C)=O.
Cc1cc(N)cc(B(O)O)c1S(=O)(=O)NCCC(C)S(C)=O
Help me reduce the QED of molecule COc1cccc(C(=O)CN2CCN(CC(C)C)CC2)c1 to make it less like a drug
CCCCCCC(CN1CCN(CC(=O)c2cccc(OC)c2)CC1)C(C)C
Help me make the molecule CCCC(CC(F)=C(F)F)NC(=O)C1CCCN1C(=O)C1CCC(=O)N1 with more hydrogen bond acceptors
CCCC(N)NC(=O)C1CCCN1C(=O)C1CCC(=O)N1
Help me improve the QED of molecule CCCCCCCCC(=O)OC1CCC(CCNS(=O)(=O)c2ccc(Cl)cc2)CC1 to make it more like a drug
CC(=O)OC1CCC(CCNS(=O)(=O)c2ccc(Cl)cc2)CC1
Help me reduce the QED of molecule Cc1ccc(S(=O)(=O)N2CCC(N3C(=O)c4ccccc4C3=O)C2)s1 to make it less like a drug
CCCCCCCCc1ccc(S(=O)(=O)N2CCC(N3C(=O)c4ccccc4C3=O)C2)s1
Help me make the molecule NC(=[NH2+])N(Cc1ccc(Sc2ccccn2)o1)[C@H]1CCNC1=O with more hydrogen bond acceptors
CN(Cc1ccc(Sc2ccccn2)o1)[C@H]1CCNC1=O
help me reduce hydrogen bond acceptors and improve QED score of molecule CN(C)C(=O)CCOc1ccc(C(=O)O)cc1C(F)(F)NC(=O)C(=O)NN.
CN(C)C(=O)CCOc1ccc(C(=O)O)cc1C(F)(F)F
help me reduce LogP value and improve H-bond donors of molecule CCCC1C(=O)NCC(C(C)(C)C)=C(C(C)(C)C)C1=O.
CCCC1C(=O)NCC(C(C)(C)C(N)=[NH2+])=C(C(C)(C)C)C1=O
Help me improve the QED of molecule CCCCC(CC)COCOc1cc(C(=O)NCCc2ccccn2)ccc1OCc1cscn1 to make it more like a drug
COc1cc(C(=O)NCCc2ccccn2)ccc1OCc1cscn1
Help me reduce the number of hydrogen bond acceptors in molecule Cc1sccc1C(=O)N[C@H]1C[C@H](CNCc2cccc(Cl)n2)C1
CCCC(=CC[C@H]1C[C@H](NC(=O)c2ccsc2C)C1)Cc1cccc(Cl)n1
Help me reduce the number of hydrogen bond donors in molecule CC[C@H](c1ccncc1)N(C(N)=[NH2+])C(=O)N=c1nc(C)[nH]n1CC
CC[C@H](c1ccncc1)N(C)C(=O)N=c1nc(C)[nH]n1CC
Help me reduce the QED of molecule CC1(C)CCC[C@@H]1C(=O)NC1CC2(CC(NCc3ccccn3)C2)C1 to make it less like a drug
CC1CCC(CCC2(C)CCC[C@@H]2C(=O)NC2CC3(CC(NCc4ccccn4)C3)C2)CC1
Help me make the molecule Cc1cc(C(=O)OCC(=O)Nc2cc(Cl)c(Cl)cc2Cl)on1 with more hydrogen bond acceptors
Cc1cc(C(=O)OCC(=O)Nc2cc(Cl)c(Sc3cc(Cl)ccc3Cl)cc2Cl)on1
help me improve hydrogen bond acceptors and H-bond donors of molecule Cc1nc(CNc2ccc(C(F)(F)F)cc2C(N)=S)cs1.
Cc1nc(CNc2ccc(C(F)(F)NC(=O)C(=O)NN)cc2C(N)=S)cs1
Help me reduce the number of hydrogen bond donors in molecule CC(C)(CO)[C@@H](CNc1nc(C(F)(F)F)cs1)c1ccccc1
CC(C)(CCc1ccccc1)[C@@H](CNc1nc(C(F)(F)F)cs1)c1ccccc1
Help me reduce the QED of molecule CC1(C)CC(c2cn(-c3ccc(F)c(F)c3)cn2)CC(C)(C)O1 to make it less like a drug
CCCC(CCBr)CC1(C)C[C@@H](c2cn(-c3ccc(F)c(F)c3)cn2)CC(C)(C)O1
Help me make the molecule CCC(CCNC(=O)NCC1(C)Cc2ccccc2C1)C(C)(C)CC with more hydrogen bond donors
CCC(O)CCNC(=O)NCC1(C)Cc2ccccc2C1
Help me reduce the number of hydrogen bond donors in molecule CC(C[NH+](CO)CC1CCCCC1NC(=O)Nc1ccc2c(n1)CCCC2=O)C(=O)[O-]
O=C(Nc1ccc2c(n1)CCCC2=O)NC1CCCCC1CO
Help me make the molecule Cc1cc(C(N)=O)ccc1NC(=O)N[C@H](C)C1(c2ccccc2)CCCC1 with more hydrogen bond acceptors
C[C@@H](NC(=O)Nc1ccc(C(N)=O)cc1B(O)O)C1(c2ccccc2)CCCC1
help me reduce QED score and improve H-bond donors of molecule CC(=O)ON1C(C)(C)CC(OCC(O)CCO)CC1(C)C.
CC(=O)ON1C(C)(C)CC(OCC(O)CCO)CC1(C)C(N)=[NH2+]
Help me reduce the number of hydrogen bond donors in molecule COC[C@@H](NC(=O)OC(C)(C)C)C(=O)NC[C@@]12CCCO[C@@H]1CCN(C(=O)[C@H](C)n1cccn1)C2
C=CCC(COC)CC(CC[C@@]12CCCO[C@@H]1CCN(C(=O)[C@H](C)n1cccn1)C2)NC(=O)OC(C)(C)C
help me improve hydrogen bond acceptors and H-bond donors of molecule CCn1cc(C(=O)NC[C@@H]2CCCN(CCC(C)C)C2)cn1.
CCn1cc(C(=O)NC[C@@H]2CCCN(CC(O)C(=O)O)C2)cn1
Help me reduce the number of hydrogen bond acceptors in molecule COc1ccc(Cl)cc1NC(=O)Cn1c(=O)n(Cc2ccco2)c(=O)c2sccc21
CCC(CC)CC(CC)c1ccc(Cl)cc1NC(=O)Cn1c(=O)n(Cc2ccco2)c(=O)c2sccc21
Help me reduce the number of hydrogen bond donors in molecule Cn1nccc1C1=CC2CCC(C1)N2C(=O)c1ccc(O)c(F)c1F
Cn1nccc1C1=CC2CCC(C1)N2C(=O)c1ccc(-c2ccc(Br)cc2)c(F)c1F
Help me reduce the number of hydrogen bond donors in molecule CCCCCCC(Nc1ccc2[nH]nc(NC(=O)c3ccc(N4CCN(CCC)CC4)cc3NC3CCOCC3)c2c1)c1cc(F)cc(F)c1
CCCN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(S(=O)(=O)c5cc(F)cc(F)c5)cc34)c(NC3CCOCC3)c2)CC1
Help me make the molecule CCC(C)(C)C1CCc2c(sc(NC(=O)C3CC=CCC3C(=O)[O-])c2C(N)=O)C1 with more hydrogen bond acceptors
CC(O)(CO)C(CO)C1CCc2c(sc(NC(=O)C3CC=CCC3C(=O)[O-])c2C(N)=O)C1
Help me reduce the QED of molecule CC(C)COCCNC(=O)Cc1nc(CCl)cs1 to make it less like a drug
C[C@@H](COCCNC(=O)Cc1nc(CCl)cs1)C(N)=[NH2+]
help me reduce H-bond donors and improve LogP value of molecule CC[C@@H](CNC(=O)C(N)=[NH2+])NCc1ccn(CCc2ccccc2)n1.
CC[C@@H](CNC(C)=O)NCc1ccn(CCc2ccccc2)n1
help me reduce hydrogen bond acceptors and improve LogP value of molecule CC(C[NH+](CNC(=O)C1(c2ccc(Cl)c(Cl)c2)CCC1)Cc1n[nH]c(=S)n1C)C(=O)[O-].
Cn1c(CNC(=O)C2(c3ccc(Cl)c(Cl)c3)CCC2)n[nH]c1=S
Help me reduce the number of hydrogen bond donors in molecule CS(=O)(=O)Cc1noc(-c2cc(N)ccc2B(O)O)n1
Cc1ccc(N)cc1-c1nc(CS(C)(=O)=O)no1
Help me reduce the number of hydrogen bond acceptors in molecule CC(=O)c1sc(-c2cc(C(=O)NCC3CNC(C)CN3)nc(-c3ccc(F)nc3C)c2)c(NC2=NCCN2)c1C
Cc1nc(F)ccc1-c1cc(CNC2=NCCN2)cc(C(=O)NCC2CNC(C)CN2)n1
Help me reduce the QED of molecule COc1cc(CN[C@H]2CCCNC2)ccc1OCc1cccs1 to make it less like a drug
CC(Oc1cc(CN[C@H]2CCCNC2)ccc1OCc1cccs1)c1ccc(Cl)cc1
Help me reduce the number of hydrogen bond acceptors in molecule CC(C)(C)OC(=O)[C@@H](C(=O)OCCc1cnc(B(O)O)cn1)C1CCCC1
Cc1cnc(CCOC(=O)[C@H](C(=O)OC(C)(C)C)C2CCCC2)cn1
Help me reduce the number of hydrogen bond acceptors in molecule CC1=C(C(=O)OC(C)C)C(C(N)=O)n2c(sc(=Cc3ccc(-c4ccc(C(=O)OC(C)C)cc4)o3)c2=O)=N1
CC1=C(C(=O)OC(C)C)C(c2ccc(Cl)cc2)n2c(sc(=Cc3ccc(-c4ccc(C(=O)OC(C)C)cc4)o3)c2=O)=N1
Help me reduce the number of hydrogen bond donors in molecule CC(C)(O)c1ncc(-c2cc3c(cc2F)nc2n3C3CC2N(CCO[Si](C)(C)C(C)(C)C)c2cccc(OC(F)F)c23)cn1
C=C(CCC)[Si](C)(OCC)[C@@H](C)c1ncc(-c2cc3c(cc2F)nc2n3C3CC2N(CCO[Si](C)(C)C(C)(C)C)c2cccc(OC(F)F)c23)cn1
Help me reduce the number of hydrogen bond donors in molecule CCOc1ccc(C(=O)CC2(O)C(=O)N(Cc3ccc(Cl)cc3)c3ccc(Cl)cc32)cc1
CCCCCCCCCCC1(CC(=O)c2ccc(OCC)cc2)C(=O)N(Cc2ccc(Cl)cc2)c2ccc(Cl)cc21
help me reduce hydrogen bond acceptors and H-bond donors and improve LogP value of molecule Cc1scc(C(=O)O[C@H](C(=O)O)c2ccc(C#N)cc2)c1B(O)O.
Cc1scc(C(=O)O[C@H](C(=O)O)c2ccc(C#N)cc2)c1C
Help me make the molecule CC(C)n1c(N2CCN(Cc3ccc4c(c3)OCO4)CC2)nc2c(NCc3cccc(C(F)(F)F)c3)ncnc21 with more hydrogen bond donors
CC(C)C[NH+](CC(=O)[O-])C(F)(F)c1cccc(CNc2ncnc3c2nc(N2CCN(Cc4ccc5c(c4)OCO5)CC2)n3C(C)C)c1
Help me improve the QED of molecule CCSc1ccccc1N(C(=O)c1ccc(OCc2c(C)noc2C)c(OC)c1)C1CCC(C)CC1 to make it more like a drug
COc1cc(C(=O)N(C)C2CCC(C)CC2)ccc1OCc1c(C)noc1C
Help me reduce the number of hydrogen bond acceptors in molecule CCSc1ccccc1N(C(=O)C1(C)CCCC1)[C@@H]1CCN(Cc2cccc(COC)c2)C1
COCc1cccc(CN2CC[C@@H](N(C)C(=O)C3(C)CCCC3)C2)c1
help me improve hydrogen bond acceptors and H-bond donors of molecule Cc1cc(OCC(=O)NCc2ccc(S(=O)(=O)N(C)C)cc2)ccc1C(C)C.
CC(C)c1ccc(OCC(=O)NCc2ccc(S(=O)(=O)N(C)C)cc2)cc1B(O)O
Help me improve the QED of molecule CC(C)(C)OC(=O)N1Cc2ccc(C(=Cc3ccc(Br)cc3)[C@H](C#N)c3ccc4ccccc4n3)cc2C1 to make it more like a drug
CC(C)(C)OC(=O)N1Cc2ccc(C(=O)[C@H](C#N)c3ccc4ccccc4n3)cc2C1
Help me make the molecule CCCCC(CCC1CCC1)NC(=O)c1nc(-c2ccccc2F)oc1C with more hydrogen bond acceptors
Cc1oc(-c2ccccc2F)nc1C(=O)N[C@@H](CO)CC1CCC1
Help me reduce the number of hydrogen bond acceptors in molecule CCc1cc(C(=O)N2CC[C@]3(C2)CN(C(=O)C(O)O)CCN3C(=O)OCc2ccccc2)cc(C)n1
CCNC1CCC(C(=O)N2CCN(C(=O)OCc3ccccc3)[C@]3(CCN(C(=O)c4cc(C)nc(CC)c4)C3)C2)CC1
Help me reduce the QED of molecule CCn1nc2c(c1C(=O)N1CCc3cc(C#N)ccc3C1)CC(C)OC2C to make it less like a drug
CCn1nc2c(c1C(=O)N1CCc3cc(C#N)ccc3C1)CC(C)OC2c1cc(Br)ccc1Br
help me reduce hydrogen bond acceptors and H-bond donors of molecule Cc1cccc(B(O)O)c1C(=O)NCc1ccc(OC(F)(F)F)cc1.
Cc1cccc(C)c1C(=O)NCc1ccc(OC(F)(F)F)cc1
Help me reduce the QED of molecule CC(C)(C)NCC1(CN2CCCC2(C)C)CCCCCC1 to make it less like a drug
CC(C)(C)NCC1(CN2CCCC2(C)C(N)=[NH2+])CCCCCC1
help me improve hydrogen bond acceptors and H-bond donors of molecule Cc1nc2sc3c(c2c(-c2ccc(Cl)c(Cl)c2)c1C(=O)C(F)(F)F)CCC3.
Cc1nc2sc3c(c2c(-c2ccc(C(=NN)NN)c(Cl)c2)c1C(=O)C(F)(F)F)CCC3
help me reduce hydrogen bond acceptors and improve LogP value and QED score of molecule CCN1CCC[C@H]1CNCc1cc(C(F)(F)NC(=O)C(=O)NN)ccc1Br.
CCN1CCC[C@H]1CNCc1cc(C(F)(F)F)ccc1Br
Help me make the molecule C[C@H](OC(=O)c1ccncc1F)C(=O)N1c2ccccc2CC[C@H]1C with more hydrogen bond acceptors
CCC(CC)(CC)SC(OC(=O)c1ccncc1F)C(=O)N1c2ccccc2CC[C@H]1C
help me reduce LogP value and improve H-bond donors of molecule Cc1ccc(NC(=O)NC2CCN(C)CC2)cc1C(=O)O.
CN1CCC(NC(=O)Nc2ccc(B(O)O)c(C(=O)O)c2)CC1