| Trigger,Date,Location,Number of Killed,Number of Injured | |
| Lac-Mégantic rail disaster,6 July 2013,"Lac-Mégantic, Quebec",47, | |
| Spanish River derailment,21 January 1910,"near Nairn, Sudbury District, Northern Ontario",, | |
| 2013 Ottawa bus–train crash,18 September 2013,"Ottawa, Ontario",,35 | |
| Hinton train collision,8 February 1986,"Dalehurst, Alberta",, | |
| Cheakamus River derailment,5 August 2005,"Cheakamus River, British Columbia",, | |
| 1979 Mississauga train derailment,10 November 1979,"Mississauga, Ontario",, | |
| Dorion level crossing accident,7 October 1966,"Dorion, Quebec",19, | |
| 1995 Russell Hill subway accident,11 August 1995,"Toronto, Ontario",, | |
| Great Western Railway disaster,12 March 1857,"Hamilton, Ontario",59,18 | |
| Canoe River train crash,21 November 1950,"near Valemount, British Columbia",21, | |
| 2012 Burlington Via derailment,26 February 2012,"Burlington, Ontario",3,46 | |
| Rogers Pass avalanche,4 March 1910,"Rogers Pass, British Columbia",62, | |
| St-Hilaire train disaster,29 June 1864,"Otterburn Park, near Mont-Saint-Hilaire, Quebec",99,100 | |
| Dugald rail accident,1 September 1947,"Dugald, Manitoba",31, | |
| Jeannette's Creek train wreck,27 October 1854,"Chatham-Kent, Ontario",52,48 | |
| 2001 Stewiacke Via derailment,12 April 2001,"Stewiacke, Nova Scotia",, | |
| Ponton train derailment,15 September 2018,"Ponton, Manitoba",, | |