Datasets:
File size: 77,880 Bytes
1d1f5f3 | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499 500 501 502 503 504 505 506 507 508 509 510 511 512 513 514 515 516 517 518 519 520 521 522 523 524 525 526 527 528 529 530 531 532 533 534 535 536 537 538 539 540 541 542 543 544 545 546 547 548 549 550 551 552 553 554 555 556 557 558 559 560 561 562 563 564 565 566 567 568 569 570 571 572 573 574 575 576 577 578 579 580 581 582 583 584 585 586 587 588 589 590 591 592 593 594 595 596 597 598 599 600 601 602 603 604 605 606 607 608 609 610 611 612 613 614 615 616 617 618 619 620 621 622 623 624 625 626 627 628 629 630 631 632 633 634 635 636 637 638 639 640 641 642 643 644 645 646 647 648 649 650 651 652 653 654 655 656 657 658 659 660 661 662 663 664 665 666 667 668 669 670 671 672 673 674 675 676 677 678 679 680 681 682 683 684 685 686 687 688 689 690 691 692 693 694 695 696 697 698 699 700 701 702 703 704 705 706 707 708 709 710 711 712 713 714 715 716 717 718 719 720 721 722 723 724 725 726 727 728 729 730 731 732 733 734 735 736 737 738 739 740 741 742 743 744 745 746 747 748 749 750 751 752 753 754 755 756 757 758 759 760 761 762 763 764 765 766 767 768 769 770 771 772 773 774 775 776 777 778 779 780 781 782 783 784 785 786 787 788 789 790 791 792 793 794 795 796 797 798 799 800 801 802 803 804 805 806 807 808 809 810 811 812 813 814 815 816 817 818 819 820 821 822 823 824 825 826 827 828 829 830 831 832 833 834 835 836 837 838 839 840 841 842 843 844 845 846 847 848 849 850 851 852 853 854 855 856 857 858 859 860 861 862 863 864 865 866 867 868 869 870 871 872 873 874 875 876 877 878 879 880 881 882 883 884 885 886 887 888 889 890 891 892 893 894 895 896 897 898 899 900 901 902 903 904 905 906 907 908 909 910 911 912 913 914 915 916 917 918 919 920 921 922 923 924 925 926 927 928 929 930 931 932 933 934 935 936 937 938 939 940 941 942 943 944 945 946 947 948 949 950 951 952 953 954 955 956 957 958 959 960 961 962 963 964 965 966 967 968 969 970 971 972 973 974 975 976 977 978 979 980 981 982 983 984 985 986 987 988 989 990 991 992 993 994 995 996 997 998 999 1000 1001 1002 1003 1004 1005 1006 1007 1008 1009 1010 1011 1012 1013 1014 1015 1016 1017 1018 1019 1020 1021 1022 1023 1024 1025 1026 1027 1028 1029 1030 1031 1032 1033 1034 1035 1036 1037 1038 1039 1040 1041 1042 1043 1044 1045 1046 1047 1048 1049 1050 1051 1052 1053 1054 1055 1056 1057 1058 1059 1060 1061 1062 1063 1064 1065 1066 1067 1068 1069 1070 1071 1072 1073 1074 1075 1076 1077 1078 1079 1080 1081 1082 1083 1084 1085 1086 1087 1088 1089 1090 1091 1092 1093 1094 1095 1096 1097 1098 1099 1100 1101 1102 1103 1104 1105 1106 1107 1108 1109 1110 1111 1112 1113 1114 1115 1116 1117 1118 1119 1120 1121 1122 1123 1124 1125 1126 1127 1128 1129 1130 1131 1132 1133 1134 1135 1136 1137 1138 1139 1140 1141 1142 1143 1144 1145 1146 1147 1148 1149 1150 1151 1152 1153 1154 1155 1156 1157 1158 1159 1160 1161 1162 1163 1164 1165 1166 | class_id,class_name,number_annotated,source
R-HSA-2500257,Resolution of Sister Chromatid Cohesion,127,reactome
R-HSA-5693568,Resolution of D-loop Structures through Holliday Junction Intermediates,35,reactome
R-HSA-912446,Meiotic recombination,88,reactome
R-HSA-2029481,FCGR activation,12,reactome
R-HSA-432142,Platelet sensitization by LDL,17,reactome
R-HSA-6798695,Neutrophil degranulation,478,reactome
R-HSA-9664323,FCGR3A-mediated IL10 synthesis,38,reactome
R-HSA-9664422,FCGR3A-mediated phagocytosis,59,reactome
R-HSA-977606,Regulation of Complement cascade,47,reactome
R-HSA-381426,Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs),124,reactome
R-HSA-8957275,Post-translational protein phosphorylation,107,reactome
R-HSA-174403,Glutathione synthesis and recycling,12,reactome
R-HSA-9818027,NFE2L2 regulating anti-oxidant/detoxification enzymes,19,reactome
R-HSA-1989781,PPARA activates gene expression,116,reactome
R-HSA-2426168,Activation of gene expression by SREBF (SREBP),42,reactome
R-HSA-380994,ATF4 activates genes in response to endoplasmic reticulum stress,27,reactome
R-HSA-381183,ATF6 (ATF6-alpha) activates chaperone genes,10,reactome
R-HSA-9614657,FOXO-mediated transcription of cell death genes,16,reactome
R-HSA-5223345,Miscellaneous transport and binding events,26,reactome
R-HSA-6791226,Major pathway of rRNA processing in the nucleolus and cytosol,183,reactome
R-HSA-382556,ABC-family proteins mediated transport,68,reactome
R-HSA-5678895,Defective CFTR causes cystic fibrosis,48,reactome
R-HSA-5689880,Ub-specific processing proteases,199,reactome
R-HSA-8856825,Cargo recognition for clathrin-mediated endocytosis,105,reactome
R-HSA-8856828,Clathrin-mediated endocytosis,129,reactome
R-HSA-9013406,RHOQ GTPase cycle,59,reactome
R-HSA-9613829,Chaperone Mediated Autophagy,22,reactome
R-HSA-9615710,Late endosomal microautophagy,34,reactome
R-HSA-9646399,Aggrephagy,44,reactome
R-HSA-9925563,Developmental Lineage of Pancreatic Ductal Cells,48,reactome
R-HSA-191273,Cholesterol biosynthesis,24,reactome
R-HSA-211976,Endogenous sterols,24,reactome
R-HSA-9619665,EGR2 and SOX10-mediated initiation of Schwann cell myelination,29,reactome
R-HSA-3108214,SUMOylation of DNA damage response and repair proteins,77,reactome
R-HSA-5685938,HDR through Single Strand Annealing (SSA),37,reactome
R-HSA-5685939,HDR through MMEJ (alt-NHEJ),12,reactome
R-HSA-111447,Activation of BAD and translocation to mitochondria ,15,reactome
R-HSA-193648,NRAGE signals death through JNK,59,reactome
R-HSA-198323,AKT phosphorylates targets in the cytosol,14,reactome
R-HSA-5674400,Constitutive Signaling by AKT1 E17K in Cancer,26,reactome
R-HSA-198933,Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell,132,reactome
R-HSA-202733,Cell surface interactions at the vascular wall,87,reactome
R-HSA-2022928,HS-GAG biosynthesis,31,reactome
R-HSA-211945,Phase I - Functionalization of compounds,22,reactome
R-HSA-3238698,WNT ligand biogenesis and trafficking,26,reactome
R-HSA-373080,Class B/2 (Secretin family receptors),51,reactome
R-HSA-4641258,Degradation of DVL,44,reactome
R-HSA-141444,Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal,94,reactome
R-HSA-2467813,Separation of Sister Chromatids,178,reactome
R-HSA-5663220,RHO GTPases Activate Formins,140,reactome
R-HSA-68877,Mitotic Prometaphase,113,reactome
R-HSA-9648025,EML4 and NUDC in mitotic spindle formation,117,reactome
R-HSA-432720,Lysosome Vesicle Biogenesis,35,reactome
R-HSA-6811440,Retrograde transport at the Trans-Golgi-Network,49,reactome
R-HSA-9840310,Glycosphingolipid catabolism,39,reactome
R-HSA-8951664,Neddylation,232,reactome
R-HSA-983168,Antigen processing: Ubiquitination & Proteasome degradation,295,reactome
R-HSA-5365859,RA biosynthesis pathway,22,reactome
R-HSA-8876198,RAB GEFs exchange GTP for GDP on RABs,90,reactome
R-HSA-9013149,RAC1 GTPase cycle,184,reactome
R-HSA-6803207,TP53 Regulates Transcription of Caspase Activators and Caspases,12,reactome
R-HSA-933543,NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10,13,reactome
R-HSA-3371378,Regulation by c-FLIP,11,reactome
R-HSA-5213460,RIPK1-mediated regulated necrosis,22,reactome
R-HSA-5218900,CASP8 activity is inhibited,11,reactome
R-HSA-5357905,Regulation of TNFR1 signaling,48,reactome
R-HSA-69416,Dimerization of procaspase-8,11,reactome
R-HSA-6799198,Complex I biogenesis,68,reactome
R-HSA-72163,mRNA Splicing - Major Pathway,204,reactome
R-HSA-1660517,Synthesis of PIPs at the late endosome membrane,11,reactome
R-HSA-1855183,"Synthesis of IP2, IP, and Ins in the cytosol",14,reactome
R-HSA-352230,Amino acid transport across the plasma membrane,33,reactome
R-HSA-6807878,COPI-mediated anterograde transport,102,reactome
R-HSA-6811434,COPI-dependent Golgi-to-ER retrograde traffic,100,reactome
R-HSA-936964,"Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)",18,reactome
R-HSA-937041,IKK complex recruitment mediated by RIP1,23,reactome
R-HSA-937072,TRAF6-mediated induction of TAK1 complex within TLR4 complex,16,reactome
R-HSA-416700,Other semaphorin interactions,19,reactome
R-HSA-9013508,NOTCH3 Intracellular Domain Regulates Transcription,25,reactome
R-HSA-9696270,RND2 GTPase cycle,43,reactome
R-HSA-499943,Interconversion of nucleotide di- and triphosphates,29,reactome
R-HSA-196807,Nicotinate metabolism,13,reactome
R-HSA-3371453,Regulation of HSF1-mediated heat shock response,82,reactome
R-HSA-3371497,HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand,57,reactome
R-HSA-3371511,HSF1 activation,31,reactome
R-HSA-3371568,Attenuation phase,28,reactome
R-HSA-3371571,HSF1-dependent transactivation,34,reactome
R-HSA-8939211,ESR-mediated signaling,11,reactome
R-HSA-9018519,Estrogen-dependent gene expression,149,reactome
R-HSA-9679191,Potential therapeutics for SARS,98,reactome
R-HSA-3214815,HDACs deacetylate histones,94,reactome
R-HSA-3214842,HDMs demethylate histones,50,reactome
R-HSA-5625886,Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3,66,reactome
R-HSA-8943724,Regulation of PTEN gene transcription,61,reactome
R-HSA-9029569,NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux,37,reactome
R-HSA-983231,Factors involved in megakaryocyte development and platelet production,109,reactome
R-HSA-111932,CaMK IV-mediated phosphorylation of CREB,10,reactome
R-HSA-9013148,CDC42 GTPase cycle,155,reactome
R-HSA-611105,Respiratory electron transport,88,reactome
R-HSA-77289,Mitochondrial Fatty Acid Beta-Oxidation,19,reactome
R-HSA-9857492,Protein lipoylation,10,reactome
R-HSA-204174,Regulation of pyruvate dehydrogenase (PDH) complex,15,reactome
R-HSA-5362517,Signaling by Retinoic Acid,19,reactome
R-HSA-9841922,MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis,134,reactome
R-HSA-549127,Organic cation transport,10,reactome
R-HSA-1268020,Mitochondrial protein import,65,reactome
R-HSA-8963693,Aspartate and asparagine metabolism,11,reactome
R-HSA-141430,Inactivation of APC/C via direct inhibition of the APC/C complex,21,reactome
R-HSA-174048,APC/C:Cdc20 mediated degradation of Cyclin B,24,reactome
R-HSA-174084,Autodegradation of Cdh1 by Cdh1:APC/C,54,reactome
R-HSA-174154,APC/C:Cdc20 mediated degradation of Securin,55,reactome
R-HSA-174178,APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1,61,reactome
R-HSA-174184,Cdc20:Phospho-APC/C mediated degradation of Cyclin A,60,reactome
R-HSA-176407,Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase,20,reactome
R-HSA-176408,Regulation of APC/C activators between G1/S and early anaphase,25,reactome
R-HSA-176409,APC/C:Cdc20 mediated degradation of mitotic proteins,21,reactome
R-HSA-176412,Phosphorylation of the APC/C,20,reactome
R-HSA-179409,APC-Cdc20 mediated degradation of Nek2A,26,reactome
R-HSA-2559582,Senescence-Associated Secretory Phenotype (SASP),111,reactome
R-HSA-68867,Assembly of the pre-replicative complex,69,reactome
R-HSA-69017,CDK-mediated phosphorylation and removal of Cdc6,60,reactome
R-HSA-8853884,Transcriptional Regulation by VENTX,39,reactome
R-HSA-9687136,Aberrant regulation of mitotic exit in cancer due to RB1 defects,20,reactome
R-HSA-1237044,Erythrocytes take up carbon dioxide and release oxygen,13,reactome
R-HSA-425381,Bicarbonate transporters,10,reactome
R-HSA-418555,G alpha (s) signalling events,145,reactome
R-HSA-419812,Calcitonin-like ligand receptors,10,reactome
R-HSA-201681,TCF dependent signaling in response to WNT,36,reactome
R-HSA-2028269,Signaling by Hippo,20,reactome
R-HSA-4086400,PCP/CE pathway,21,reactome
R-HSA-4608870,Asymmetric localization of PCP proteins,51,reactome
R-HSA-4641262,Disassembly of the destruction complex and recruitment of AXIN to the membrane,31,reactome
R-HSA-5099900,WNT5A-dependent internalization of FZD4,15,reactome
R-HSA-9673324,WNT5:FZD7-mediated leishmania damping,12,reactome
R-HSA-975956,Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC),96,reactome
R-HSA-975957,Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC),116,reactome
R-HSA-391160,Signal regulatory protein family interactions,16,reactome
R-HSA-83936,Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane,12,reactome
R-HSA-9837999,Mitochondrial protein degradation,98,reactome
R-HSA-8949215,Mitochondrial calcium ion transport,13,reactome
R-HSA-8949664,Processing of SMDT1,16,reactome
R-HSA-9830674,Formation of the ureteric bud,21,reactome
R-HSA-112382,Formation of RNA Pol II elongation complex ,58,reactome
R-HSA-113418,Formation of the Early Elongation Complex,33,reactome
R-HSA-167152,Formation of HIV elongation complex in the absence of HIV Tat,45,reactome
R-HSA-167158,Formation of the HIV-1 Early Elongation Complex,33,reactome
R-HSA-167160,RNA Pol II CTD phosphorylation and interaction with CE during HIV infection,27,reactome
R-HSA-167161,HIV Transcription Initiation,47,reactome
R-HSA-167162,RNA Polymerase II HIV Promoter Escape,47,reactome
R-HSA-167172,Transcription of the HIV genome,47,reactome
R-HSA-167200,Formation of HIV-1 elongation complex containing HIV-1 Tat,43,reactome
R-HSA-167238,Pausing and recovery of Tat-mediated HIV elongation,31,reactome
R-HSA-167242,Abortive elongation of HIV-1 transcript in the absence of Tat,23,reactome
R-HSA-167243,Tat-mediated HIV elongation arrest and recovery,31,reactome
R-HSA-167246,Tat-mediated elongation of the HIV-1 transcript,41,reactome
R-HSA-167287,HIV elongation arrest and recovery,33,reactome
R-HSA-167290,Pausing and recovery of HIV elongation,33,reactome
R-HSA-168325,Viral Messenger RNA Synthesis,44,reactome
R-HSA-203927,MicroRNA (miRNA) biogenesis,24,reactome
R-HSA-5578749,Transcriptional regulation by small RNAs,106,reactome
R-HSA-5601884,PIWI-interacting RNA (piRNA) biogenesis,29,reactome
R-HSA-5617472,Activation of anterior HOX genes in hindbrain development during early embryogenesis,122,reactome
R-HSA-674695,RNA Polymerase II Pre-transcription Events,81,reactome
R-HSA-6781823,Formation of TC-NER Pre-Incision Complex,51,reactome
R-HSA-6781827,Transcription-Coupled Nucleotide Excision Repair (TC-NER),42,reactome
R-HSA-6782135,Dual incision in TC-NER,63,reactome
R-HSA-6782210,Gap-filling DNA repair synthesis and ligation in TC-NER,62,reactome
R-HSA-6796648,TP53 Regulates Transcription of DNA Repair Genes,62,reactome
R-HSA-6803529,FGFR2 alternative splicing,27,reactome
R-HSA-6807505,RNA polymerase II transcribes snRNA genes,74,reactome
R-HSA-72086,mRNA Capping,29,reactome
R-HSA-72165,mRNA Splicing - Minor Pathway,50,reactome
R-HSA-72203,Processing of Capped Intron-Containing Pre-mRNA,70,reactome
R-HSA-73776,RNA Polymerase II Promoter Escape,47,reactome
R-HSA-73779,RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,47,reactome
R-HSA-75953,RNA Polymerase II Transcription Initiation,47,reactome
R-HSA-75955,RNA Polymerase II Transcription Elongation,56,reactome
R-HSA-76042,RNA Polymerase II Transcription Initiation And Promoter Clearance,47,reactome
R-HSA-77075,RNA Pol II CTD phosphorylation and interaction with CE,27,reactome
R-HSA-8851708,Signaling by FGFR2 IIIa TM,19,reactome
R-HSA-9670095,Inhibition of DNA recombination at telomere,67,reactome
R-HSA-5083635,Defective B3GALTL causes PpS,37,reactome
R-HSA-5173214,O-glycosylation of TSR domain-containing proteins,38,reactome
R-HSA-5696397,Gap-filling DNA repair synthesis and ligation in GG-NER,25,reactome
R-HSA-9913635,Strand-asynchronous mitochondrial DNA replication,10,reactome
R-HSA-2564830,Cytosolic iron-sulfur cluster assembly,13,reactome
R-HSA-163615,PKA activation,18,reactome
R-HSA-164378,PKA activation in glucagon signalling,17,reactome
R-HSA-180024,DARPP-32 events,24,reactome
R-HSA-2565942,Regulation of PLK1 Activity at G2/M Transition,87,reactome
R-HSA-380259,Loss of Nlp from mitotic centrosomes,69,reactome
R-HSA-380270,Recruitment of mitotic centrosome proteins and complexes,81,reactome
R-HSA-380284,Loss of proteins required for interphase microtubule organization from the centrosome,69,reactome
R-HSA-380320,Recruitment of NuMA to mitotic centrosomes,95,reactome
R-HSA-381676,Glucagon-like Peptide-1 (GLP1) regulates insulin secretion,42,reactome
R-HSA-432040,Vasopressin regulates renal water homeostasis via Aquaporins,43,reactome
R-HSA-442720,CREB1 phosphorylation through the activation of Adenylate Cyclase,12,reactome
R-HSA-5610787,Hedgehog 'off' state,56,reactome
R-HSA-5620912,Anchoring of the basal body to the plasma membrane,97,reactome
R-HSA-8854518,AURKA Activation by TPX2,72,reactome
R-HSA-9634597,GPER1 signaling,45,reactome
R-HSA-9660821,ADORA2B mediated anti-inflammatory cytokines production,43,reactome
R-HSA-9856530,High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells,69,reactome
R-HSA-3214847,HATs acetylate histones,142,reactome
R-HSA-1234158,Regulation of gene expression by Hypoxia-inducible Factor,11,reactome
R-HSA-1368108,"BMAL1:CLOCK,NPAS2 activates circadian expression",26,reactome
R-HSA-1912408,Pre-NOTCH Transcription and Translation,92,reactome
R-HSA-201722,Formation of the beta-catenin:TCF transactivating complex,89,reactome
R-HSA-210744,Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells,16,reactome
R-HSA-2122947,NOTCH1 Intracellular Domain Regulates Transcription,48,reactome
R-HSA-2151201,Transcriptional activation of mitochondrial biogenesis,55,reactome
R-HSA-2644606,Constitutive Signaling by NOTCH1 PEST Domain Mutants,58,reactome
R-HSA-2894862,Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants,58,reactome
R-HSA-350054,Notch-HLH transcription pathway,28,reactome
R-HSA-381340,Transcriptional regulation of white adipocyte differentiation,84,reactome
R-HSA-3899300,SUMOylation of transcription cofactors,44,reactome
R-HSA-400206,Regulation of lipid metabolism by PPARalpha,20,reactome
R-HSA-5621575,CD209 (DC-SIGN) signaling,21,reactome
R-HSA-6803204,TP53 Regulates Transcription of Genes Involved in Cytochrome C Release,20,reactome
R-HSA-8866907,Activation of the TFAP2 (AP-2) family of transcription factors,12,reactome
R-HSA-8941856,RUNX3 regulates NOTCH signaling,14,reactome
R-HSA-9013695,NOTCH4 Intracellular Domain Regulates Transcription,20,reactome
R-HSA-918233,TRAF3-dependent IRF activation pathway,15,reactome
R-HSA-933541,TRAF6 mediated IRF7 activation,30,reactome
R-HSA-9617629,Regulation of FOXO transcriptional activity by acetylation,10,reactome
R-HSA-9705671,SARS-CoV-2 activates/modulates innate and adaptive immune responses,126,reactome
R-HSA-9707564,Cytoprotection by HMOX1,56,reactome
R-HSA-9707616,Heme signaling,49,reactome
R-HSA-9768919,NPAS4 regulates expression of target genes,22,reactome
R-HSA-9793380,Formation of paraxial mesoderm,22,reactome
R-HSA-9818030,NFE2L2 regulating tumorigenic genes,11,reactome
R-HSA-9819196,Zygotic genome activation (ZGA),17,reactome
R-HSA-9833109,Evasion by RSV of host interferon responses,35,reactome
R-HSA-9856649,Transcriptional and post-translational regulation of MITF-M expression and activity,62,reactome
R-HSA-9931509,"Expression of BMAL (ARNTL), CLOCK, and NPAS2",36,reactome
R-HSA-9931510,Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes,22,reactome
R-HSA-9931512,"Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters",11,reactome
R-HSA-9931521,The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex,14,reactome
R-HSA-9933387,"RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression",26,reactome
R-HSA-181429,Serotonin Neurotransmitter Release Cycle,18,reactome
R-HSA-181430,Norepinephrine Neurotransmitter Release Cycle,18,reactome
R-HSA-196108,Pregnenolone biosynthesis,12,reactome
R-HSA-210500,Glutamate Neurotransmitter Release Cycle,24,reactome
R-HSA-212676,Dopamine Neurotransmitter Release Cycle,23,reactome
R-HSA-264642,Acetylcholine Neurotransmitter Release Cycle,17,reactome
R-HSA-9033241,Peroxisomal protein import,63,reactome
R-HSA-212436,Generic Transcription Pathway,350,reactome
R-HSA-390471,Association of TriC/CCT with target proteins during biosynthesis,39,reactome
R-HSA-9932298,Degradation of CRY and PER proteins,48,reactome
R-HSA-216083,Integrin cell surface interactions,85,reactome
R-HSA-210991,Basigin interactions,25,reactome
R-HSA-3000157,Laminin interactions,30,reactome
R-HSA-8874081,MET activates PTK2 signaling,30,reactome
R-HSA-114608,Platelet degranulation ,127,reactome
R-HSA-3000178,ECM proteoglycans,76,reactome
R-HSA-354192,Integrin signaling,23,reactome
R-HSA-354194,GRB2:SOS provides linkage to MAPK signaling for Integrins ,15,reactome
R-HSA-372708,p130Cas linkage to MAPK signaling for integrins,15,reactome
R-HSA-445144,Signal transduction by L1,21,reactome
R-HSA-5674135,MAP2K and MAPK activation,40,reactome
R-HSA-6802946,Signaling by moderate kinase activity BRAF mutants,45,reactome
R-HSA-6802948,Signaling by high-kinase activity BRAF mutants,36,reactome
R-HSA-6802952,Signaling by BRAF and RAF1 fusions,65,reactome
R-HSA-6802955,Paradoxical activation of RAF signaling by kinase inactive BRAF,45,reactome
R-HSA-8936459,RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function,95,reactome
R-HSA-9649948,Signaling downstream of RAS mutants,45,reactome
R-HSA-9656223,Signaling by RAF1 mutants,41,reactome
R-HSA-6788467,IL-6-type cytokine receptor ligand interactions,17,reactome
R-HSA-9020956,Interleukin-27 signaling,11,reactome
R-HSA-192105,Synthesis of bile acids and bile salts,14,reactome
R-HSA-6805567,Keratinization,155,reactome
R-HSA-6809371,Formation of the cornified envelope,129,reactome
R-HSA-389357,CD28 dependent PI3K/Akt signaling,27,reactome
R-HSA-5607761,Dectin-1 mediated noncanonical NF-kB signaling,49,reactome
R-HSA-5668541,TNFR2 non-canonical NF-kB pathway,55,reactome
R-HSA-5676590,NIK-->noncanonical NF-kB signaling,46,reactome
R-HSA-5676594,TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway,17,reactome
R-HSA-422356,Regulation of insulin secretion,28,reactome
R-HSA-399719,Trafficking of AMPA receptors,17,reactome
R-HSA-5682910,LGI-ADAM interactions,14,reactome
R-HSA-177504,Retrograde neurotrophin signalling,14,reactome
R-HSA-2132295,MHC class II antigen presentation,126,reactome
R-HSA-3928665,EPH-ephrin mediated repulsion of cells,51,reactome
R-HSA-416993,Trafficking of GluR2-containing AMPA receptors,17,reactome
R-HSA-437239,Recycling pathway of L1,49,reactome
R-HSA-5140745,"WNT5A-dependent internalization of FZD2, FZD5 and ROR2",13,reactome
R-HSA-8866427,VLDLR internalisation and degradation,16,reactome
R-HSA-8964038,LDL clearance,19,reactome
R-HSA-416476,G alpha (q) signalling events,174,reactome
R-HSA-380108,Chemokine receptors bind chemokines,57,reactome
R-HSA-418594,G alpha (i) signalling events,258,reactome
R-HSA-419037,NCAM1 interactions,42,reactome
R-HSA-445355,Smooth Muscle Contraction,43,reactome
R-HSA-8939902,Regulation of RUNX2 expression and activity,59,reactome
R-HSA-1445148,Translocation of SLC2A4 (GLUT4) to the plasma membrane,72,reactome
R-HSA-171007,p38MAPK events,13,reactome
R-HSA-8950505,Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation,38,reactome
R-HSA-9013404,RAC2 GTPase cycle,88,reactome
R-HSA-9013423,RAC3 GTPase cycle,94,reactome
R-HSA-9035034,RHOF GTPase cycle,42,reactome
R-HSA-9845614,Sphingolipid catabolism,12,reactome
R-HSA-399955,SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion,14,reactome
R-HSA-9662360,Sensory processing of sound by inner hair cells of the cochlea,69,reactome
R-HSA-9662361,Sensory processing of sound by outer hair cells of the cochlea,50,reactome
R-HSA-176187,Activation of ATR in response to replication stress,37,reactome
R-HSA-68962,Activation of the pre-replicative complex,33,reactome
R-HSA-416482,G alpha (12/13) signalling events,80,reactome
R-HSA-428930,Thromboxane signalling through TP receptor,24,reactome
R-HSA-189451,Heme biosynthesis,14,reactome
R-HSA-8866654,E3 ubiquitin ligases ubiquitinate target proteins,59,reactome
R-HSA-9754560,SARS-CoV-2 modulates autophagy,11,reactome
R-HSA-8980692,RHOA GTPase cycle,149,reactome
R-HSA-6784531,tRNA processing in the nucleus,58,reactome
R-HSA-1663150,The activation of arylsulfatases,13,reactome
R-HSA-163560,Triglyceride catabolism,24,reactome
R-HSA-73614,Pyrimidine salvage,11,reactome
R-HSA-73621,Pyrimidine catabolism,12,reactome
R-HSA-163125,Post-translational modification: synthesis of GPI-anchored proteins,66,reactome
R-HSA-6811436,COPI-independent Golgi-to-ER retrograde traffic,53,reactome
R-HSA-1222556,ROS and RNS production in phagocytes,34,reactome
R-HSA-6785807,Interleukin-4 and Interleukin-13 signaling,108,reactome
R-HSA-204005,COPII-mediated vesicle transport,69,reactome
R-HSA-8863795,Downregulation of ERBB2 signaling,24,reactome
R-HSA-983695,Antigen activates B Cell Receptor (BCR) leading to generation of second messengers,29,reactome
R-HSA-445095,Interaction between L1 and Ankyrins,31,reactome
R-HSA-5576892,Phase 0 - rapid depolarisation,32,reactome
R-HSA-210745,Regulation of gene expression in beta cells,18,reactome
R-HSA-381771,"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)",21,reactome
R-HSA-400511,"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)",13,reactome
R-HSA-9823739,Formation of the anterior neural plate,11,reactome
R-HSA-112308,Presynaptic depolarization and calcium channel opening,11,reactome
R-HSA-400042,"Adrenaline,noradrenaline inhibits insulin secretion",28,reactome
R-HSA-5576893,Phase 2 - plateau phase,15,reactome
R-HSA-6790901,rRNA modification in the nucleus and cytosol,60,reactome
R-HSA-162710,Synthesis of glycosylphosphatidylinositol (GPI),18,reactome
R-HSA-2032785,YAP1- and WWTR1 (TAZ)-stimulated gene expression,15,reactome
R-HSA-8949613,Cristae formation,33,reactome
R-HSA-5668599,RHO GTPases Activate NADPH Oxidases,24,reactome
R-HSA-2559580,Oxidative Stress Induced Senescence,123,reactome
R-HSA-2559585,Oncogene Induced Senescence,33,reactome
R-HSA-69231,Cyclin D associated events in G1,47,reactome
R-HSA-9661069,"Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)",17,reactome
R-HSA-1169091,Activation of NF-kappaB in B cells,54,reactome
R-HSA-1234176,Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha,53,reactome
R-HSA-1236974,ER-Phagosome pathway,82,reactome
R-HSA-1236978,Cross-presentation of soluble exogenous antigens (endosomes),41,reactome
R-HSA-174113,SCF-beta-TrCP mediated degradation of Emi1,42,reactome
R-HSA-180534,Vpu mediated degradation of CD4,39,reactome
R-HSA-180585,Vif-mediated degradation of APOBEC3G,41,reactome
R-HSA-187577,SCF(Skp2)-mediated degradation of p27/p21,50,reactome
R-HSA-195253,Degradation of beta-catenin by the destruction complex,56,reactome
R-HSA-202424,Downstream TCR signaling,84,reactome
R-HSA-211733,Regulation of activated PAK-2p34 by proteasome mediated degradation,37,reactome
R-HSA-2871837,FCERI mediated NF-kB activation,68,reactome
R-HSA-349425,Autodegradation of the E3 ubiquitin ligase COP1,39,reactome
R-HSA-350562,Regulation of ornithine decarboxylase (ODC),38,reactome
R-HSA-450408,AUF1 (hnRNP D0) binds and destabilizes mRNA,42,reactome
R-HSA-4641257,Degradation of AXIN,42,reactome
R-HSA-5358346,Hedgehog ligand biogenesis,47,reactome
R-HSA-5362768,Hh mutants are degraded by ERAD,43,reactome
R-HSA-5607764,CLEC7A (Dectin-1) signaling,66,reactome
R-HSA-5610780,Degradation of GLI1 by the proteasome,47,reactome
R-HSA-5610783,Degradation of GLI2 by the proteasome,47,reactome
R-HSA-5610785,GLI3 is processed to GLI3R by the proteasome,47,reactome
R-HSA-5632684,Hedgehog 'on' state,60,reactome
R-HSA-5658442,Regulation of RAS by GAPs,55,reactome
R-HSA-5687128,MAPK6/MAPK4 signaling,78,reactome
R-HSA-5689603,UCH proteinases,88,reactome
R-HSA-68949,Orc1 removal from chromatin,58,reactome
R-HSA-69481,G2/M Checkpoints,38,reactome
R-HSA-69601,Ubiquitin Mediated Degradation of Phosphorylated Cdc25A,39,reactome
R-HSA-75815,Ubiquitin-dependent degradation of Cyclin D,39,reactome
R-HSA-8852276,The role of GTSE1 in G2/M progression after G2 checkpoint,66,reactome
R-HSA-8854050,FBXL7 down-regulates AURKA during mitotic entry and in early mitosis,42,reactome
R-HSA-8939236,RUNX1 regulates transcription of genes involved in differentiation of HSCs,116,reactome
R-HSA-8941858,Regulation of RUNX3 expression and activity,45,reactome
R-HSA-8948751,Regulation of PTEN stability and activity,56,reactome
R-HSA-9010553,Regulation of expression of SLITs and ROBOs,159,reactome
R-HSA-9020702,Interleukin-1 signaling,74,reactome
R-HSA-9604323,Negative regulation of NOTCH4 signaling,44,reactome
R-HSA-9755511,KEAP1-NFE2L2 pathway,64,reactome
R-HSA-9762114,GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2,42,reactome
R-HSA-9824272,Somitogenesis,45,reactome
R-HSA-9907900,Proteasome assembly,52,reactome
R-HSA-9912633,"Antigen processing: Ub, ATP-independent proteasomal degradation",19,reactome
R-HSA-212300,PRC2 methylates histones and DNA,72,reactome
R-HSA-3232118,SUMOylation of transcription factors,20,reactome
R-HSA-8866904,Negative regulation of activity of TFAP2 (AP-2) family transcription factors,10,reactome
R-HSA-8866910,TFAP2 (AP-2) family regulates transcription of growth factors and their receptors,15,reactome
R-HSA-9834899,Specification of the neural plate border,17,reactome
R-HSA-6811438,Intra-Golgi traffic,44,reactome
R-HSA-525793,Myogenesis,29,reactome
R-HSA-156590,Glutathione conjugation,24,reactome
R-HSA-5423646,Aflatoxin activation and detoxification,18,reactome
R-HSA-9931530,Phosphorylation and nuclear translocation of the CRY:PER:kinase complex,14,reactome
R-HSA-6803157,Antimicrobial peptides,38,reactome
R-HSA-73980,RNA Polymerase III Transcription Termination,23,reactome
R-HSA-749476,RNA Polymerase III Abortive And Retractive Initiation,41,reactome
R-HSA-2022854,Keratan sulfate biosynthesis,28,reactome
R-HSA-4085001,Sialic acid metabolism,33,reactome
R-HSA-9694548,Maturation of spike protein,41,reactome
R-HSA-977068,Termination of O-glycan biosynthesis,23,reactome
R-HSA-1592389,Activation of Matrix Metalloproteinases,33,reactome
R-HSA-449836,Other interleukin signaling,24,reactome
R-HSA-5620916,VxPx cargo-targeting to cilium,21,reactome
R-HSA-9833110,RSV-host interactions,65,reactome
R-HSA-9013418,RHOBTB2 GTPase cycle,23,reactome
R-HSA-156827,L13a-mediated translational silencing of Ceruloplasmin expression,112,reactome
R-HSA-156902,Peptide chain elongation,90,reactome
R-HSA-1799339,SRP-dependent cotranslational protein targeting to membrane,113,reactome
R-HSA-192823,Viral mRNA Translation,90,reactome
R-HSA-2408557,Selenocysteine synthesis,94,reactome
R-HSA-72649,Translation initiation complex formation,59,reactome
R-HSA-72689,Formation of a pool of free 40S subunits,102,reactome
R-HSA-72695,"Formation of the ternary complex, and subsequently, the 43S complex",52,reactome
R-HSA-72702,Ribosomal scanning and start codon recognition,59,reactome
R-HSA-72706,GTP hydrolysis and joining of the 60S ribosomal subunit,113,reactome
R-HSA-72764,Eukaryotic Translation Termination,94,reactome
R-HSA-9633012,Response of EIF2AK4 (GCN2) to amino acid deficiency,102,reactome
R-HSA-9735869,SARS-CoV-1 modulates host translation machinery,37,reactome
R-HSA-9754678,SARS-CoV-2 modulates host translation machinery,50,reactome
R-HSA-110312,Translesion synthesis by REV1,16,reactome
R-HSA-5655862,Translesion synthesis by POLK,17,reactome
R-HSA-5656121,Translesion synthesis by POLI,17,reactome
R-HSA-166663,Initial triggering of complement,17,reactome
R-HSA-5173105,O-linked glycosylation,15,reactome
R-HSA-162588,Budding and maturation of HIV virion,28,reactome
R-HSA-917729,Endosomal Sorting Complex Required For Transport (ESCRT),31,reactome
R-HSA-5250924,B-WICH complex positively regulates rRNA expression,90,reactome
R-HSA-5693565,Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks,77,reactome
R-HSA-373760,L1CAM interactions,13,reactome
R-HSA-5673001,RAF/MAP kinase cascade,131,reactome
R-HSA-8851805,MET activates RAS signaling,11,reactome
R-HSA-9861718,Regulation of pyruvate metabolism,18,reactome
R-HSA-110320,Translesion Synthesis by POLH,19,reactome
R-HSA-9865881,Complex III assembly,26,reactome
R-HSA-2514853,Condensation of Prometaphase Chromosomes,11,reactome
R-HSA-420092,Glucagon-type ligand receptors,33,reactome
R-HSA-9696264,RND3 GTPase cycle,42,reactome
R-HSA-442660,Na+/Cl- dependent neurotransmitter transporters,19,reactome
R-HSA-2024096,HS-GAG degradation,24,reactome
R-HSA-2024101,CS/DS degradation,14,reactome
R-HSA-1462054,Alpha-defensins,10,reactome
R-HSA-9725554,Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin,39,reactome
R-HSA-9758881,Uptake of dietary cobalamins into enterocytes,10,reactome
R-HSA-202427,Phosphorylation of CD3 and TCR zeta chains,22,reactome
R-HSA-202430,Translocation of ZAP-70 to Immunological synapse,19,reactome
R-HSA-202433,Generation of second messenger molecules,34,reactome
R-HSA-389948,Co-inhibition by PD-1,23,reactome
R-HSA-166058,MyD88:MAL(TIRAP) cascade initiated on plasma membrane,26,reactome
R-HSA-2029482,Regulation of actin dynamics for phagocytic cup formation,61,reactome
R-HSA-2424491,DAP12 signaling,29,reactome
R-HSA-2871809,FCERI mediated Ca+2 mobilization,31,reactome
R-HSA-5602498,MyD88 deficiency (TLR2/4),17,reactome
R-HSA-5603041,IRAK4 deficiency (TLR2/4),18,reactome
R-HSA-5663213,RHO GTPases Activate WASPs and WAVEs,36,reactome
R-HSA-8964315,G beta:gamma signalling through BTK,18,reactome
R-HSA-917977,Transferrin endocytosis and recycling,31,reactome
R-HSA-4551638,SUMOylation of chromatin organization proteins,71,reactome
R-HSA-4570464,SUMOylation of RNA binding proteins,47,reactome
R-HSA-4655427,SUMOylation of DNA methylation proteins,16,reactome
R-HSA-8939243,RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known,37,reactome
R-HSA-114604,GPVI-mediated activation cascade,35,reactome
R-HSA-1227986,Signaling by ERBB2,18,reactome
R-HSA-1257604,PIP3 activates AKT signaling,105,reactome
R-HSA-1433557,Signaling by SCF-KIT,37,reactome
R-HSA-1433559,Regulation of KIT signaling,16,reactome
R-HSA-210990,PECAM1 interactions,12,reactome
R-HSA-2219530,Constitutive Signaling by Aberrant PI3K in Cancer,86,reactome
R-HSA-2682334,EPH-Ephrin signaling,26,reactome
R-HSA-2730905,Role of LAT2/NTAL/LAB on calcium mobilization,16,reactome
R-HSA-373753,Nephrin family interactions,23,reactome
R-HSA-375165,NCAM signaling for neurite out-growth,22,reactome
R-HSA-389356,Co-stimulation by CD28,19,reactome
R-HSA-389359,CD28 dependent Vav1 pathway,12,reactome
R-HSA-389513,Co-inhibition by CTLA4,21,reactome
R-HSA-3928662,EPHB-mediated forward signaling,42,reactome
R-HSA-3928663,EPHA-mediated growth cone collapse,29,reactome
R-HSA-3928664,Ephrin signaling,19,reactome
R-HSA-399954,Sema3A PAK dependent Axon repulsion,16,reactome
R-HSA-399956,CRMPs in Sema3A signaling,16,reactome
R-HSA-418885,DCC mediated attractive signaling,14,reactome
R-HSA-4420097,VEGFA-VEGFR2 Pathway,62,reactome
R-HSA-5621480,Dectin-2 family,26,reactome
R-HSA-6811558,"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling",114,reactome
R-HSA-75892,Platelet Adhesion to exposed collagen,16,reactome
R-HSA-912631,Regulation of signaling by CBL,22,reactome
R-HSA-9670439,"Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants",20,reactome
R-HSA-9680350,Signaling by CSF1 (M-CSF) in myeloid cells,31,reactome
R-HSA-1614558,Degradation of cysteine and homocysteine,10,reactome
R-HSA-2672351,Stimuli-sensing channels,78,reactome
R-HSA-71288,Creatine metabolism,10,reactome
R-HSA-6794361,Neurexins and neuroligins,56,reactome
R-HSA-190373,FGFR1c ligand binding and activation,14,reactome
R-HSA-5654726,Negative regulation of FGFR1 signaling,26,reactome
R-HSA-9772755,Formation of WDR5-containing histone-modifying complexes,42,reactome
R-HSA-936440,Negative regulators of DDX58/IFIH1 signaling,35,reactome
R-HSA-9824585,Regulation of MITF-M-dependent genes involved in pigmentation,42,reactome
R-HSA-9845323,Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs),97,reactome
R-HSA-9933937,Formation of the canonical BAF (cBAF) complex,18,reactome
R-HSA-9934037,Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF),25,reactome
R-HSA-379726,Mitochondrial tRNA aminoacylation,21,reactome
R-HSA-1660499,Synthesis of PIPs at the plasma membrane,53,reactome
R-HSA-1660514,Synthesis of PIPs at the Golgi membrane,18,reactome
R-HSA-1660516,Synthesis of PIPs at the early endosome membrane,16,reactome
R-HSA-432722,Golgi Associated Vesicle Biogenesis,56,reactome
R-HSA-75205,Dissolution of Fibrin Clot,13,reactome
R-HSA-9013026,RHOB GTPase cycle,70,reactome
R-HSA-9013106,RHOC GTPase cycle,74,reactome
R-HSA-8854214,TBC/RABGAPs,44,reactome
R-HSA-1474228,Degradation of the extracellular matrix,81,reactome
R-HSA-1971475,A tetrasaccharide linker sequence is required for GAG synthesis,27,reactome
R-HSA-2022870,Chondroitin sulfate biosynthesis,20,reactome
R-HSA-2022923,Dermatan sulfate biosynthesis,11,reactome
R-HSA-3560783,"Defective B4GALT7 causes EDS, progeroid type",20,reactome
R-HSA-3560801,Defective B3GAT3 causes JDSSDHD,20,reactome
R-HSA-4420332,Defective B3GALT6 causes EDSP2 and SEMDJL1,20,reactome
R-HSA-5675221,Negative regulation of MAPK pathway,41,reactome
R-HSA-2172127,DAP12 interactions,24,reactome
R-HSA-977443,GABA receptor activation,17,reactome
R-HSA-1221632,Meiotic synapsis,78,reactome
R-HSA-5685942,HDR through Homologous Recombination (HRR),49,reactome
R-HSA-5689901,Metalloprotease DUBs,37,reactome
R-HSA-5693554,Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA),27,reactome
R-HSA-5693571,Nonhomologous End-Joining (NHEJ),68,reactome
R-HSA-5693579,Homologous DNA Pairing and Strand Exchange,26,reactome
R-HSA-5693607,Processing of DNA double-strand break ends,97,reactome
R-HSA-5693616,Presynaptic phase of homologous DNA pairing and strand exchange,40,reactome
R-HSA-6804756,Regulation of TP53 Activity through Phosphorylation,92,reactome
R-HSA-69473,G2/M DNA damage checkpoint,83,reactome
R-HSA-8953750,Transcriptional Regulation by E2F6,34,reactome
R-HSA-9701192,Defective homologous recombination repair (HRR) due to BRCA1 loss of function,25,reactome
R-HSA-9704331,Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function,25,reactome
R-HSA-9704646,Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function,25,reactome
R-HSA-9709570,Impaired BRCA2 binding to RAD51,35,reactome
R-HSA-9709603,Impaired BRCA2 binding to PALB2,24,reactome
R-HSA-5696395,Formation of Incision Complex in GG-NER,43,reactome
R-HSA-5696400,Dual Incision in GG-NER,41,reactome
R-HSA-6783310,Fanconi Anemia Pathway,38,reactome
R-HSA-1655829,Regulation of cholesterol biosynthesis by SREBP (SREBF),15,reactome
R-HSA-8963889,Assembly of active LPL and LIPC lipase complexes,19,reactome
R-HSA-977225,Amyloid fiber formation,110,reactome
R-HSA-381038,XBP1(S) activates chaperone genes,48,reactome
R-HSA-159418,Recycling of bile acids and salts,18,reactome
R-HSA-193368,Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol,23,reactome
R-HSA-193807,Synthesis of bile acids and bile salts via 27-hydroxycholesterol,14,reactome
R-HSA-383280,Nuclear Receptor transcription pathway,53,reactome
R-HSA-4090294,SUMOylation of intracellular receptors,30,reactome
R-HSA-2046106,alpha-linolenic acid (ALA) metabolism,13,reactome
R-HSA-75876,Synthesis of very long-chain fatty acyl-CoAs,24,reactome
R-HSA-2142691,Synthesis of Leukotrienes (LT) and Eoxins (EX),20,reactome
R-HSA-420029,Tight junction interactions,30,reactome
R-HSA-1834949,Cytosolic sensors of pathogen-associated DNA ,23,reactome
R-HSA-73780,RNA Polymerase III Chain Elongation,18,reactome
R-HSA-76061,RNA Polymerase III Transcription Initiation From Type 1 Promoter,28,reactome
R-HSA-76066,RNA Polymerase III Transcription Initiation From Type 2 Promoter,27,reactome
R-HSA-76071,RNA Polymerase III Transcription Initiation From Type 3 Promoter,28,reactome
R-HSA-2197563,NOTCH2 intracellular domain regulates transcription,12,reactome
R-HSA-9013507,NOTCH3 Activation and Transmission of Signal to the Nucleus,24,reactome
R-HSA-113501,Inhibition of replication initiation of damaged DNA by RB1/E2F1,13,reactome
R-HSA-174411,Polymerase switching on the C-strand of the telomere,26,reactome
R-HSA-174430,Telomere C-strand synthesis initiation,13,reactome
R-HSA-69091,Polymerase switching,14,reactome
R-HSA-69166,Removal of the Flap Intermediate,14,reactome
R-HSA-69183,Processive synthesis on the lagging strand,10,reactome
R-HSA-9710421,Defective pyroptosis,72,reactome
R-HSA-9930044,Nuclear RNA decay,35,reactome
R-HSA-8862803,Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models,22,reactome
R-HSA-9864848,Complex IV assembly,48,reactome
R-HSA-9013409,RHOJ GTPase cycle,55,reactome
R-HSA-9733709,Cardiogenesis,27,reactome
R-HSA-8854691,Interleukin-20 family signaling,26,reactome
R-HSA-936837,Ion transport by P-type ATPases,55,reactome
R-HSA-422085,"Synthesis, secretion, and deacylation of Ghrelin",19,reactome
R-HSA-2122948,Activated NOTCH1 Transmits Signal to the Nucleus,31,reactome
R-HSA-2979096,NOTCH2 Activation and Transmission of Signal to the Nucleus,25,reactome
R-HSA-2173795,Downregulation of SMAD2/3:SMAD4 transcriptional activity,31,reactome
R-HSA-2173796,SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription,36,reactome
R-HSA-5578768,Physiological factors,14,reactome
R-HSA-8940973,RUNX2 regulates osteoblast differentiation,24,reactome
R-HSA-5578775,Ion homeostasis,53,reactome
R-HSA-3000480,Scavenging by Class A Receptors,19,reactome
R-HSA-196791,Vitamin D (calciferol) metabolism,12,reactome
R-HSA-1266695,Interleukin-7 signaling,36,reactome
R-HSA-6807004,Negative regulation of MET activity,21,reactome
R-HSA-8875555,MET activates RAP1 and RAC1,11,reactome
R-HSA-8875656,MET receptor recycling,10,reactome
R-HSA-5689896,Ovarian tumor domain proteases,39,reactome
R-HSA-427413,NoRC negatively regulates rRNA expression,105,reactome
R-HSA-69202,Cyclin E associated events during G1/S transition ,28,reactome
R-HSA-69273,Cyclin A/B1/B2 associated events during G2/M transition,32,reactome
R-HSA-69656,Cyclin A:Cdk2-associated events at S phase entry,30,reactome
R-HSA-73762,RNA Polymerase I Transcription Initiation,47,reactome
R-HSA-73772,RNA Polymerase I Promoter Escape,90,reactome
R-HSA-73863,RNA Polymerase I Transcription Termination,31,reactome
R-HSA-8951936,RUNX3 regulates p14-ARF,10,reactome
R-HSA-2559586,DNA Damage/Telomere Stress Induced Senescence,65,reactome
R-HSA-3270619,IRF3-mediated induction of type I IFN,13,reactome
R-HSA-211958,Miscellaneous substrates,12,reactome
R-HSA-211981,Xenobiotics,22,reactome
R-HSA-9668328,Sealing of the nuclear envelope (NE) by ESCRT-III,32,reactome
R-HSA-1482801,Acyl chain remodelling of PS,22,reactome
R-HSA-70635,Urea cycle,10,reactome
R-HSA-1236394,Signaling by ERBB4,19,reactome
R-HSA-1632852,Macroautophagy,68,reactome
R-HSA-168638,NOD1/2 Signaling Pathway,36,reactome
R-HSA-168927,"TICAM1, RIP1-mediated IKK complex recruitment",19,reactome
R-HSA-5357786,TNFR1-induced proapoptotic signaling,25,reactome
R-HSA-5357956,TNFR1-induced NF-kappa-B signaling pathway,33,reactome
R-HSA-5675482,Regulation of necroptotic cell death,26,reactome
R-HSA-71336,Pentose phosphate pathway,12,reactome
R-HSA-2173788,Downregulation of TGF-beta receptor signaling,26,reactome
R-HSA-189483,Heme degradation,15,reactome
R-HSA-9749641,Aspirin ADME,44,reactome
R-HSA-9753281,Paracetamol ADME,29,reactome
R-HSA-165159,MTOR signalling,17,reactome
R-HSA-166208,mTORC1-mediated signalling,24,reactome
R-HSA-380972,Energy dependent regulation of mTOR by LKB1-AMPK,29,reactome
R-HSA-5628897,TP53 Regulates Metabolic Genes,84,reactome
R-HSA-9639288,Amino acids regulate mTORC1,55,reactome
R-HSA-6804757,Regulation of TP53 Degradation,36,reactome
R-HSA-6804759,Regulation of TP53 Activity through Association with Co-factors,14,reactome
R-HSA-69541,Stabilization of p53,11,reactome
R-HSA-2453902,The canonical retinoid cycle in rods (twilight vision),22,reactome
R-HSA-2299718,Condensation of Prophase Chromosomes,73,reactome
R-HSA-68616,Assembly of the ORC complex at the origin of replication,68,reactome
R-HSA-264870,Caspase-mediated cleavage of cytoskeletal proteins,12,reactome
R-HSA-390522,Striated Muscle Contraction,36,reactome
R-HSA-9013422,RHOBTB1 GTPase cycle,23,reactome
R-HSA-140534,Caspase activation via Death Receptors in the presence of ligand,15,reactome
R-HSA-6803211,TP53 Regulates Transcription of Death Receptors and Ligands,12,reactome
R-HSA-2160916,Hyaluronan uptake and degradation,12,reactome
R-HSA-877300,Interferon gamma signaling,90,reactome
R-HSA-1296072,Voltage gated Potassium channels,43,reactome
R-HSA-1483166,Synthesis of PA,39,reactome
R-HSA-8851680,Butyrophilin (BTN) family interactions,12,reactome
R-HSA-114508,Effects of PIP2 hydrolysis,22,reactome
R-HSA-418597,G alpha (z) signalling events,48,reactome
R-HSA-877312,Regulation of IFNG signaling,14,reactome
R-HSA-2995383,Initiation of Nuclear Envelope (NE) Reformation,19,reactome
R-HSA-9013405,RHOD GTPase cycle,53,reactome
R-HSA-9013408,RHOG GTPase cycle,74,reactome
R-HSA-5669034,TNFs bind their physiological receptors,29,reactome
R-HSA-6783783,Interleukin-10 signaling,45,reactome
R-HSA-9933947,Formation of the non-canonical BAF (ncBAF) complex,17,reactome
R-HSA-1169408,ISG15 antiviral mechanism,74,reactome
R-HSA-159227,Transport of the SLBP independent Mature mRNA,35,reactome
R-HSA-159230,Transport of the SLBP Dependant Mature mRNA,36,reactome
R-HSA-159231,Transport of Mature mRNA Derived from an Intronless Transcript,42,reactome
R-HSA-159236,Transport of Mature mRNA derived from an Intron-Containing Transcript,75,reactome
R-HSA-165054,Rev-mediated nuclear export of HIV RNA,35,reactome
R-HSA-168271,Transport of Ribonucleoproteins into the Host Nucleus,32,reactome
R-HSA-168276,NS1 Mediated Effects on Host Pathways,38,reactome
R-HSA-168333,NEP/NS2 Interacts with the Cellular Export Machinery,32,reactome
R-HSA-170822,Regulation of Glucokinase by Glucokinase Regulatory Protein,32,reactome
R-HSA-180746,Nuclear import of Rev protein,34,reactome
R-HSA-180910,Vpr-mediated nuclear import of PICs,34,reactome
R-HSA-191859,snRNP Assembly,53,reactome
R-HSA-3232142,SUMOylation of ubiquitinylation proteins,39,reactome
R-HSA-3301854,Nuclear Pore Complex (NPC) Disassembly,36,reactome
R-HSA-4085377,SUMOylation of SUMOylation proteins,35,reactome
R-HSA-4615885,SUMOylation of DNA replication proteins,46,reactome
R-HSA-5619107,Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC),32,reactome
R-HSA-9609690,HCMV Early Events,138,reactome
R-HSA-9610379,HCMV Late Events,116,reactome
R-HSA-9615933,Postmitotic nuclear pore complex (NPC) reformation,27,reactome
R-HSA-5620971,Pyroptosis,27,reactome
R-HSA-9013420,RHOU GTPase cycle,40,reactome
R-HSA-606279,Deposition of new CENPA-containing nucleosomes at the centromere,72,reactome
R-HSA-379716,Cytosolic tRNA aminoacylation,24,reactome
R-HSA-5620924,Intraflagellar transport,54,reactome
R-HSA-446193,"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein",15,reactome
R-HSA-9843970,Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex,70,reactome
R-HSA-438066,"Unblocking of NMDA receptors, glutamate binding and activation",21,reactome
R-HSA-442982,Ras activation upon Ca2+ influx through NMDA receptor,20,reactome
R-HSA-9609736,Assembly and cell surface presentation of NMDA receptors,44,reactome
R-HSA-9617324,Negative regulation of NMDA receptor-mediated neuronal transmission,21,reactome
R-HSA-9620244,Long-term potentiation,23,reactome
R-HSA-975578,Reactions specific to the complex N-glycan synthesis pathway,10,reactome
R-HSA-8866652,Synthesis of active ubiquitin: roles of E1 and E2 enzymes,30,reactome
R-HSA-109704,PI3K Cascade,39,reactome
R-HSA-1839117,Signaling by cytosolic FGFR1 fusion mutants,18,reactome
R-HSA-8853659,RET signaling,40,reactome
R-HSA-8983432,Interleukin-15 signaling,14,reactome
R-HSA-912526,Interleukin receptor SHC signaling,27,reactome
R-HSA-9607240,FLT3 Signaling,19,reactome
R-HSA-9674555,Signaling by CSF3 (G-CSF),19,reactome
R-HSA-9702518,STAT5 activation downstream of FLT3 ITD mutants,10,reactome
R-HSA-9703465,Signaling by FLT3 fusion proteins,19,reactome
R-HSA-9703648,Signaling by FLT3 ITD and TKD mutants,10,reactome
R-HSA-77387,Insulin receptor recycling,30,reactome
R-HSA-983712,Ion channel transport,24,reactome
R-HSA-9857377,Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy,17,reactome
R-HSA-9013407,RHOH GTPase cycle,37,reactome
R-HSA-450302,activated TAK1 mediates p38 MAPK activation,23,reactome
R-HSA-5210891,Uptake and function of anthrax toxins,11,reactome
R-HSA-1369062,ABC transporters in lipid homeostasis,18,reactome
R-HSA-9603798,Class I peroxisomal membrane protein import,20,reactome
R-HSA-9725370,Signaling by ALK fusions and activated point mutants,60,reactome
R-HSA-9860927,"Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells",31,reactome
R-HSA-9013424,RHOV GTPase cycle,37,reactome
R-HSA-9696273,RND1 GTPase cycle,42,reactome
R-HSA-418889,Caspase activation via Dependence Receptors in the absence of ligand,10,reactome
R-HSA-73817,Purine ribonucleoside monophosphate biosynthesis,11,reactome
R-HSA-9839383,TGFBR3 PTM regulation,11,reactome
R-HSA-110314,Recognition of DNA damage by PCNA-containing replication complex,30,reactome
R-HSA-5651801,PCNA-Dependent Long Patch Base Excision Repair,21,reactome
R-HSA-5656169,Termination of translesion DNA synthesis,32,reactome
R-HSA-9706019,RHOBTB3 ATPase cycle,10,reactome
R-HSA-193775,Synthesis of bile acids and bile salts via 24-hydroxycholesterol,13,reactome
R-HSA-420499,Class C/3 (Metabotropic glutamate/pheromone receptors),39,reactome
R-HSA-6782315,tRNA modification in the nucleus and cytosol,38,reactome
R-HSA-2129379,Molecules associated with elastic fibres,37,reactome
R-HSA-9762293,Regulation of CDH11 gene transcription,10,reactome
R-HSA-156581,Methylation,14,reactome
R-HSA-1650814,Collagen biosynthesis and modifying enzymes,67,reactome
R-HSA-2214320,Anchoring fibril formation,15,reactome
R-HSA-2243919,Crosslinking of collagen fibrils,18,reactome
R-HSA-430039,mRNA decay by 5' to 3' exoribonuclease,15,reactome
R-HSA-351906,Apoptotic cleavage of cell adhesion proteins,11,reactome
R-HSA-418990,Adherens junctions interactions,32,reactome
R-HSA-5626467,RHO GTPases activate IQGAPs,32,reactome
R-HSA-9823730,Formation of definitive endoderm,15,reactome
R-HSA-9926550,"Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition",12,reactome
R-HSA-201451,Signaling by BMP,31,reactome
R-HSA-8873719,RAB geranylgeranylation,65,reactome
R-HSA-3000170,Syndecan interactions,27,reactome
R-HSA-975634,Retinoid metabolism and transport,44,reactome
R-HSA-2871796,FCERI mediated MAPK activation,32,reactome
R-HSA-5218920,VEGFR2 mediated vascular permeability,27,reactome
R-HSA-70221,Glycogen breakdown (glycogenolysis),15,reactome
R-HSA-983170,"Antigen Presentation: Folding, assembly and peptide loading of class I MHC",29,reactome
R-HSA-9909505,Modulation of host responses by IFN-stimulated genes,19,reactome
R-HSA-917937,Iron uptake and transport,28,reactome
R-HSA-375276,Peptide ligand-binding receptors,106,reactome
R-HSA-381753,Olfactory Signaling Pathway,75,reactome
R-HSA-9733458,Induction of Cell-Cell Fusion,13,reactome
R-HSA-5368286,Mitochondrial translation initiation,88,reactome
R-HSA-5389840,Mitochondrial translation elongation,88,reactome
R-HSA-5419276,Mitochondrial translation termination,88,reactome
R-HSA-2514859,"Inactivation, recovery and regulation of the phototransduction cascade",33,reactome
R-HSA-1442490,Collagen degradation,64,reactome
R-HSA-186797,Signaling by PDGF,33,reactome
R-HSA-2022090,Assembly of collagen fibrils and other multimeric structures,51,reactome
R-HSA-8948216,Collagen chain trimerization,44,reactome
R-HSA-2173789,TGF-beta receptor signaling activates SMADs,27,reactome
R-HSA-1566948,Elastic fibre formation,18,reactome
R-HSA-3214858,RMTs methylate histone arginines,78,reactome
R-HSA-8877330,RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs),10,reactome
R-HSA-2022857,Keratan sulfate degradation,15,reactome
R-HSA-3000171,Non-integrin membrane-ECM interactions,40,reactome
R-HSA-9913351,Formation of the dystrophin-glycoprotein complex (DGC),36,reactome
R-HSA-450321,JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1,22,reactome
R-HSA-450341,Activation of the AP-1 family of transcription factors,10,reactome
R-HSA-186763,Downstream signal transduction,29,reactome
R-HSA-8849471,"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases",14,reactome
R-HSA-201556,Signaling by ALK,19,reactome
R-HSA-2029485,Role of phospholipids in phagocytosis,25,reactome
R-HSA-210993,Tie2 Signaling,18,reactome
R-HSA-512988,"Interleukin-3, Interleukin-5 and GM-CSF signaling",24,reactome
R-HSA-9027276,Erythropoietin activates Phosphoinositide-3-kinase (PI3K),12,reactome
R-HSA-9673767,"Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants",12,reactome
R-HSA-9673770,Signaling by PDGFRA extracellular domain mutants,12,reactome
R-HSA-9842663,Signaling by LTK,12,reactome
R-HSA-9927354,Co-stimulation by ICOS,11,reactome
R-HSA-3299685,Detoxification of Reactive Oxygen Species,37,reactome
R-HSA-72187,mRNA 3'-end processing,58,reactome
R-HSA-73856,RNA Polymerase II Transcription Termination,67,reactome
R-HSA-9692916,SARS-CoV-1 activates/modulates innate immune responses,41,reactome
R-HSA-446107,Type I hemidesmosome assembly,11,reactome
R-HSA-983189,Kinesins,61,reactome
R-HSA-1170546,Prolactin receptor signaling,15,reactome
R-HSA-5684264,MAP3K8 (TPL2)-dependent MAPK1/3 activation,16,reactome
R-HSA-9708530,Regulation of BACH1 activity,11,reactome
R-HSA-9725371,Nuclear events stimulated by ALK signaling in cancer,34,reactome
R-HSA-1251985,Nuclear signaling by ERBB4,32,reactome
R-HSA-445989,TAK1-dependent IKK and NF-kappa-B activation ,35,reactome
R-HSA-9014325,"TICAM1,TRAF6-dependent induction of TAK1 complex",11,reactome
R-HSA-937042,IRAK2 mediated activation of TAK1 complex,10,reactome
R-HSA-9645460,Alpha-protein kinase 1 signaling pathway,11,reactome
R-HSA-975163,IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation,15,reactome
R-HSA-4755510,SUMOylation of immune response proteins,12,reactome
R-HSA-909733,Interferon alpha/beta signaling,75,reactome
R-HSA-9833482,PKR-mediated signaling,76,reactome
R-HSA-3214841,PKMTs methylate histone lysines,70,reactome
R-HSA-9818564,Epigenetic regulation of gene expression by MLL3 and MLL4 complexes,10,reactome
R-HSA-3295583,TRP channels,28,reactome
R-HSA-3322077,Glycogen synthesis,14,reactome
R-HSA-159740,Gamma-carboxylation of protein precursors,10,reactome
R-HSA-159782,Removal of aminoterminal propeptides from gamma-carboxylated proteins,10,reactome
R-HSA-9701898,STAT3 nuclear events downstream of ALK signaling,11,reactome
R-HSA-9827857,Specification of primordial germ cells,12,reactome
R-HSA-5205685,PINK1-PRKN Mediated Mitophagy,32,reactome
R-HSA-8934903,Receptor Mediated Mitophagy,11,reactome
R-HSA-427389,ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression,75,reactome
R-HSA-9843940,Regulation of endogenous retroelements by KRAB-ZFP proteins,107,reactome
R-HSA-9844594,Transcriptional regulation of brown and beige adipocyte differentiation by EBF2,31,reactome
R-HSA-5625740,RHO GTPases activate PKNs,28,reactome
R-HSA-5625900,RHO GTPases activate CIT,19,reactome
R-HSA-5627117,RHO GTPases Activate ROCKs,19,reactome
R-HSA-5627123,RHO GTPases activate PAKs,21,reactome
R-HSA-5673000,RAF activation,34,reactome
R-HSA-9022692,Regulation of MECP2 expression and activity,31,reactome
R-HSA-418359,Reduction of cytosolic Ca++ levels,12,reactome
R-HSA-211979,Eicosanoids,12,reactome
R-HSA-2162123,Synthesis of Prostaglandins (PG) and Thromboxanes (TX),15,reactome
R-HSA-8964539,Glutamate and glutamine metabolism,14,reactome
R-HSA-189200,Cellular hexose transport,21,reactome
R-HSA-9022699,MECP2 regulates neuronal receptors and channels,18,reactome
R-HSA-112043,PLC beta mediated events,12,reactome
R-HSA-202040,G-protein activation,24,reactome
R-HSA-399997,Acetylcholine regulates insulin secretion,10,reactome
R-HSA-418592,ADP signalling through P2Y purinoceptor 1,25,reactome
R-HSA-456926,Thrombin signalling through proteinase activated receptors (PARs),32,reactome
R-HSA-6814122,Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding,38,reactome
R-HSA-70268,Pyruvate metabolism,19,reactome
R-HSA-390247,Beta-oxidation of very long chain fatty acids,11,reactome
R-HSA-70895,Branched-chain amino acid catabolism,21,reactome
R-HSA-75109,Triglyceride biosynthesis,14,reactome
R-HSA-71403,Citric acid cycle (TCA cycle),17,reactome
R-HSA-9854311,Maturation of TCA enzymes and regulation of TCA cycle,20,reactome
R-HSA-2468052,Establishment of Sister Chromatid Cohesion,11,reactome
R-HSA-2470946,Cohesin Loading onto Chromatin,10,reactome
R-HSA-174414,Processive synthesis on the C-strand of the telomere,14,reactome
R-HSA-174417,Telomere C-strand (Lagging Strand) Synthesis,11,reactome
R-HSA-174437,Removal of the Flap Intermediate from the C-strand,17,reactome
R-HSA-5358565,Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha),14,reactome
R-HSA-5358606,Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta),14,reactome
R-HSA-429947,Deadenylation of mRNA,25,reactome
R-HSA-9820841,M-decay: degradation of maternal mRNAs by maternally stored factors,33,reactome
R-HSA-9820865,Z-decay: degradation of maternal mRNAs by zygotically expressed factors,12,reactome
R-HSA-1660661,Sphingolipid de novo biosynthesis,37,reactome
R-HSA-9629569,Protein hydroxylation,20,reactome
R-HSA-182971,EGFR downregulation,31,reactome
R-HSA-3656237,Defective EXT2 causes exostoses 2,14,reactome
R-HSA-3656253,"Defective EXT1 causes exostoses 1, TRPS2 and CHDS",14,reactome
R-HSA-376176,Signaling by ROBO receptors,15,reactome
R-HSA-9694614,Attachment and Entry,19,reactome
R-HSA-9820960,Respiratory syncytial virus (RSV) attachment and entry,23,reactome
R-HSA-111465,Apoptotic cleavage of cellular proteins,18,reactome
R-HSA-9758274,Regulation of NF-kappa B signaling,18,reactome
R-HSA-1912420,Pre-NOTCH Processing in Golgi,18,reactome
R-HSA-9037629,Lewis blood group biosynthesis,16,reactome
R-HSA-193692,Regulated proteolysis of p75NTR,11,reactome
R-HSA-205043,NRIF signals cell death from the nucleus,16,reactome
R-HSA-209543,p75NTR recruits signalling complexes,13,reactome
R-HSA-209560,NF-kB is activated and signals survival,13,reactome
R-HSA-5635838,Activation of SMO,18,reactome
R-HSA-419408,Lysosphingolipid and LPA receptors,14,reactome
R-HSA-110328,Recognition and association of DNA glycosylase with site containing an affected pyrimidine,60,reactome
R-HSA-110329,Cleavage of the damaged pyrimidine ,60,reactome
R-HSA-170670,Adenylate cyclase inhibitory pathway,14,reactome
R-HSA-392170,ADP signalling through P2Y purinoceptor 12,22,reactome
R-HSA-9009391,Extra-nuclear estrogen signaling,56,reactome
R-HSA-373752,Netrin-1 signaling,19,reactome
R-HSA-418890,Role of second messengers in netrin-1 signaling,10,reactome
R-HSA-428542,Regulation of commissural axon pathfinding by SLIT and ROBO,10,reactome
R-HSA-1250196,SHC1 events in ERBB2 signaling,22,reactome
R-HSA-1358803,Downregulation of ERBB2:ERBB3 signaling,13,reactome
R-HSA-1963642,PI3K events in ERBB2 signaling,16,reactome
R-HSA-6785631,ERBB2 Regulates Cell Motility,15,reactome
R-HSA-8847993,ERBB2 Activates PTK6 Signaling,13,reactome
R-HSA-9664565,Signaling by ERBB2 KD Mutants,25,reactome
R-HSA-9665686,Signaling by ERBB2 TMD/JMD mutants,22,reactome
R-HSA-2408522,Selenoamino acid metabolism,11,reactome
R-HSA-9648002,RAS processing,24,reactome
R-HSA-3769402,Deactivation of the beta-catenin transactivating complex,42,reactome
R-HSA-4641265,Repression of WNT target genes,14,reactome
R-HSA-196757,Metabolism of folate and pterines,17,reactome
R-HSA-196299,Beta-catenin phosphorylation cascade,17,reactome
R-HSA-5339716,Signaling by GSK3beta mutants,15,reactome
R-HSA-5358747,CTNNB1 S33 mutants aren't phosphorylated,15,reactome
R-HSA-5358749,CTNNB1 S37 mutants aren't phosphorylated,15,reactome
R-HSA-5358751,CTNNB1 S45 mutants aren't phosphorylated,15,reactome
R-HSA-5358752,CTNNB1 T41 mutants aren't phosphorylated,15,reactome
R-HSA-5467337,APC truncation mutants have impaired AXIN binding,14,reactome
R-HSA-5467340,AXIN missense mutants destabilize the destruction complex,14,reactome
R-HSA-5467348,Truncations of AMER1 destabilize the destruction complex,14,reactome
R-HSA-9933939,Formation of the polybromo-BAF (pBAF) complex,18,reactome
R-HSA-9933946,Formation of the embryonic stem cell BAF (esBAF) complex,19,reactome
R-HSA-9616222,Transcriptional regulation of granulopoiesis,89,reactome
R-HSA-5689877,Josephin domain DUBs,12,reactome
R-HSA-9615017,"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes",30,reactome
R-HSA-190375,FGFR2c ligand binding and activation,13,reactome
R-HSA-190377,FGFR2b ligand binding and activation,10,reactome
R-HSA-2033519,Activated point mutants of FGFR2,17,reactome
R-HSA-5654221,Phospholipase C-mediated cascade; FGFR2,18,reactome
R-HSA-5654695,PI-3K cascade:FGFR2,23,reactome
R-HSA-5654699,SHC-mediated cascade:FGFR2,23,reactome
R-HSA-5654700,FRS-mediated FGFR2 signaling,25,reactome
R-HSA-5654727,Negative regulation of FGFR2 signaling,27,reactome
R-HSA-5655253,Signaling by FGFR2 in disease,27,reactome
R-HSA-70171,Glycolysis,30,reactome
R-HSA-9856532,Mechanical load activates signaling by PIEZO1 and integrins in osteocytes,17,reactome
R-HSA-8876725,Protein methylation,17,reactome
R-HSA-2173791,TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition),16,reactome
R-HSA-392451,G beta:gamma signalling through PI3Kgamma,25,reactome
R-HSA-416572,Sema4D induced cell migration and growth-cone collapse,20,reactome
R-HSA-5625970,RHO GTPases activate KTN1,11,reactome
R-HSA-5218921,VEGFR2 mediated cell proliferation,19,reactome
R-HSA-888590,"GABA synthesis, release, reuptake and degradation",13,reactome
R-HSA-8878166,Transcriptional regulation by RUNX2,15,reactome
R-HSA-8934593,Regulation of RUNX1 Expression and Activity,17,reactome
R-HSA-1839130,Signaling by activated point mutants of FGFR3,12,reactome
R-HSA-190372,FGFR3c ligand binding and activation,13,reactome
R-HSA-5654227,Phospholipase C-mediated cascade; FGFR3,13,reactome
R-HSA-5654704,SHC-mediated cascade:FGFR3,18,reactome
R-HSA-5654706,FRS-mediated FGFR3 signaling,20,reactome
R-HSA-5654710,PI-3K cascade:FGFR3,18,reactome
R-HSA-5654732,Negative regulation of FGFR3 signaling,22,reactome
R-HSA-5655332,Signaling by FGFR3 in disease,22,reactome
R-HSA-198753,ERK/MAPK targets,17,reactome
R-HSA-9752946,Expression and translocation of olfactory receptors,395,reactome
R-HSA-392517,Rap1 signalling,16,reactome
R-HSA-139853,Elevation of cytosolic Ca2+ levels,15,reactome
R-HSA-5683826,Surfactant metabolism,29,reactome
R-HSA-1502540,Signaling by Activin,15,reactome
R-HSA-9839394,TGFBR3 expression,25,reactome
R-HSA-1482788,Acyl chain remodelling of PC,27,reactome
R-HSA-1482839,Acyl chain remodelling of PE,29,reactome
R-HSA-1482922,Acyl chain remodelling of PI,17,reactome
R-HSA-1482925,Acyl chain remodelling of PG,18,reactome
R-HSA-1296041,Activation of G protein gated Potassium channels,29,reactome
R-HSA-392851,Prostacyclin signalling through prostacyclin receptor,19,reactome
R-HSA-4086398,Ca2+ pathway,62,reactome
R-HSA-418217,G beta:gamma signalling through PLC beta,20,reactome
R-HSA-500657,Presynaptic function of Kainate receptors,21,reactome
R-HSA-8964616,G beta:gamma signalling through CDC42,20,reactome
R-HSA-997272,Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits,29,reactome
R-HSA-264876,Insulin processing,25,reactome
R-HSA-3772470,Negative regulation of TCF-dependent signaling by WNT ligand antagonists,15,reactome
R-HSA-4641263,Regulation of FZD by ubiquitination,21,reactome
R-HSA-5654219,Phospholipase C-mediated cascade: FGFR1,16,reactome
R-HSA-5654687,Downstream signaling of activated FGFR1,18,reactome
R-HSA-5654688,SHC-mediated cascade:FGFR1,21,reactome
R-HSA-5654689,PI-3K cascade:FGFR1,21,reactome
R-HSA-5654693,FRS-mediated FGFR1 signaling,23,reactome
R-HSA-5658623,FGFRL1 modulation of FGFR1 signaling,13,reactome
R-HSA-9937080,Developmental Lineage of Multipotent Pancreatic Progenitor Cells,18,reactome
R-HSA-1483191,Synthesis of PC,28,reactome
R-HSA-425366,"Transport of bile salts and organic acids, metal ions and amine compounds",11,reactome
R-HSA-190873,Gap junction degradation,12,reactome
R-HSA-196025,Formation of annular gap junctions,11,reactome
R-HSA-9648895,Response of EIF2AK1 (HRI) to heme deficiency,15,reactome
R-HSA-2485179,Activation of the phototransduction cascade,11,reactome
R-HSA-9828806,Maturation of hRSV A proteins,14,reactome
R-HSA-9717207,"Sensory perception of sweet, bitter, and umami (glutamate) taste",41,reactome
R-HSA-428540,Activation of RAC1,13,reactome
R-HSA-975577,N-Glycan antennae elongation,15,reactome
R-HSA-8955332,Carboxyterminal post-translational modifications of tubulin,46,reactome
R-HSA-901032,ER Quality Control Compartment (ERQC),21,reactome
R-HSA-6804758,Regulation of TP53 Activity through Acetylation,23,reactome
R-HSA-77595,Processing of Intronless Pre-mRNAs,20,reactome
R-HSA-9634600,"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism",12,reactome
R-HSA-9008059,Interleukin-37 signaling,21,reactome
R-HSA-446353,Cell-extracellular matrix interactions,12,reactome
R-HSA-9609523,Insertion of tail-anchored proteins into the endoplasmic reticulum membrane,22,reactome
R-HSA-9705462,Inactivation of CSF3 (G-CSF) signaling,25,reactome
R-HSA-5607763,CLEC7A (Dectin-1) induces NFAT activation,11,reactome
R-HSA-418457,cGMP effects,16,reactome
R-HSA-164940,Nef mediated downregulation of MHC class I complex cell surface expression,10,reactome
R-HSA-176974,Unwinding of DNA,12,reactome
R-HSA-6803205,TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain,14,reactome
R-HSA-9821002,Chromatin modifications during the maternal to zygotic transition (MZT),70,reactome
R-HSA-9796292,Formation of axial mesoderm,14,reactome
R-HSA-174490,Membrane binding and targetting of GAG proteins,14,reactome
R-HSA-1475029,Reversible hydration of carbon dioxide,12,reactome
R-HSA-425561,Sodium/Calcium exchangers,11,reactome
R-HSA-5694530,Cargo concentration in the ER,33,reactome
R-HSA-70263,Gluconeogenesis,26,reactome
R-HSA-1839122,Signaling by activated point mutants of FGFR1,11,reactome
R-HSA-190322,FGFR4 ligand binding and activation,13,reactome
R-HSA-5654228,Phospholipase C-mediated cascade; FGFR4,15,reactome
R-HSA-5654712,FRS-mediated FGFR4 signaling,22,reactome
R-HSA-5654719,SHC-mediated cascade:FGFR4,20,reactome
R-HSA-5654720,PI-3K cascade:FGFR4,20,reactome
R-HSA-5654733,Negative regulation of FGFR4 signaling,24,reactome
R-HSA-5655302,Signaling by FGFR1 in disease,33,reactome
R-HSA-389957,Prefoldin mediated transfer of substrate to CCT/TriC,28,reactome
R-HSA-390450,Folding of actin by CCT/TriC,10,reactome
R-HSA-5696394,DNA Damage Recognition in GG-NER,38,reactome
R-HSA-451308,Activation of Ca-permeable Kainate Receptor,10,reactome
R-HSA-8849932,Synaptic adhesion-like molecules,21,reactome
R-HSA-190840,Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane,20,reactome
R-HSA-190861,Gap junction assembly,38,reactome
R-HSA-389960,Formation of tubulin folding intermediates by CCT/TriC,26,reactome
R-HSA-389977,Post-chaperonin tubulin folding pathway,23,reactome
R-HSA-5617833,Cilium Assembly,20,reactome
R-HSA-9619483,Activation of AMPK downstream of NMDARs,29,reactome
R-HSA-9830364,Formation of the nephric duct,18,reactome
R-HSA-9831926,Nephron development,13,reactome
R-HSA-429958,mRNA decay by 3' to 5' exoribonuclease,16,reactome
R-HSA-450385,Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA,17,reactome
R-HSA-450513,"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA",17,reactome
R-HSA-450604,KSRP (KHSRP) binds and destabilizes mRNA,17,reactome
R-HSA-196780,Biotin transport and metabolism,11,reactome
R-HSA-200425,Carnitine shuttle,14,reactome
R-HSA-180292,GAB1 signalosome,17,reactome
R-HSA-74259,Purine catabolism,10,reactome
R-HSA-9755088,Ribavirin ADME,11,reactome
R-HSA-1810476,RIP-mediated NFkB activation via ZBP1,17,reactome
R-HSA-844456,The NLRP3 inflammasome,16,reactome
R-HSA-933542,TRAF6 mediated NF-kB activation,25,reactome
R-HSA-9660826,Purinergic signaling in leishmaniasis infection,26,reactome
R-HSA-9679504,Translation of Replicase and Assembly of the Replication Transcription Complex,13,reactome
R-HSA-9694676,Translation of Replicase and Assembly of the Replication Transcription Complex,13,reactome
R-HSA-163359,Glucagon signaling in metabolic regulation,26,reactome
R-HSA-170660,Adenylate cyclase activating pathway,10,reactome
R-HSA-417957,P2Y receptors,12,reactome
R-HSA-8986944,Transcriptional Regulation by MECP2,17,reactome
R-HSA-9824594,Regulation of MITF-M-dependent genes involved in apoptosis,18,reactome
R-HSA-1295596,Spry regulation of FGF signaling,16,reactome
R-HSA-166016,Toll Like Receptor 4 (TLR4) Cascade,18,reactome
R-HSA-9031628,NGF-stimulated transcription,39,reactome
R-HSA-1474244,Extracellular matrix organization,15,reactome
R-HSA-2022377,Metabolism of Angiotensinogen to Angiotensins,17,reactome
R-HSA-629594,Highly calcium permeable postsynaptic nicotinic acetylcholine receptors,11,reactome
R-HSA-6804115,TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain,21,reactome
R-HSA-9013700,NOTCH4 Activation and Transmission of Signal to the Nucleus,11,reactome
R-HSA-1236382,Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants,19,reactome
R-HSA-1474151,"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation",10,reactome
R-HSA-168928,DDX58/IFIH1-mediated induction of interferon-alpha/beta,23,reactome
R-HSA-203615,eNOS activation,13,reactome
R-HSA-5637810,Constitutive Signaling by EGFRvIII,15,reactome
R-HSA-9634285,Constitutive Signaling by Overexpressed ERBB2,11,reactome
R-HSA-9665348,Signaling by ERBB2 ECD mutants,16,reactome
R-HSA-1362277,Transcription of E2F targets under negative control by DREAM complex,19,reactome
R-HSA-1362300,Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1,16,reactome
R-HSA-1538133,G0 and Early G1,18,reactome
R-HSA-6804114,TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest,18,reactome
R-HSA-69205,G1/S-Specific Transcription,29,reactome
R-HSA-9754189,Germ layer formation at gastrulation,17,reactome
R-HSA-9825892,Regulation of MITF-M-dependent genes involved in cell cycle and proliferation,18,reactome
R-HSA-8984722,Interleukin-35 Signalling,12,reactome
R-HSA-9020591,Interleukin-12 signaling,10,reactome
R-HSA-5576886,Phase 4 - resting membrane potential,19,reactome
R-HSA-9683610,Maturation of nucleoprotein,11,reactome
R-HSA-9694631,Maturation of nucleoprotein,15,reactome
R-HSA-9634638,Estrogen-dependent nuclear events downstream of ESR-membrane signaling,24,reactome
R-HSA-2142789,Ubiquinol biosynthesis,13,reactome
R-HSA-879518,Transport of organic anions,11,reactome
R-HSA-5686938,Regulation of TLR by endogenous ligand,22,reactome
R-HSA-8963888,Chylomicron assembly,10,reactome
R-HSA-8963901,Chylomicron remodeling,10,reactome
R-HSA-2534343,Interaction With Cumulus Cells And The Zona Pellucida,11,reactome
R-HSA-9757110,Prednisone ADME,10,reactome
R-HSA-8875360,InlB-mediated entry of Listeria monocytogenes into host cell,15,reactome
R-HSA-9841251,Mitochondrial unfolded protein response (UPRmt),18,reactome
R-HSA-432047,Passive transport by Aquaporins,13,reactome
R-HSA-1855204,Synthesis of IP3 and IP4 in the cytosol,26,reactome
R-HSA-8964058,HDL remodeling,10,reactome
R-HSA-5661231,Metallothioneins bind metals,11,reactome
R-HSA-156584,Cytosolic sulfonation of small molecules,18,reactome
R-HSA-5334118,DNA methylation,64,reactome
R-HSA-1461957,Beta defensins,39,reactome
R-HSA-1461973,Defensins,40,reactome
R-HSA-140837,Intrinsic Pathway of Fibrin Clot Formation,23,reactome
R-HSA-532668,N-glycan trimming in the ER and Calnexin/Calreticulin cycle,16,reactome
R-HSA-6804116,TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest,14,reactome
R-HSA-9617828,FOXO-mediated transcription of cell cycle genes,17,reactome
R-HSA-76009,Platelet Aggregation (Plug Formation),10,reactome
R-HSA-9706369,Negative regulation of FLT3,15,reactome
R-HSA-428643,Organic anion transporters,12,reactome
R-HSA-9925561,Developmental Lineage of Pancreatic Acinar Cells,32,reactome
R-HSA-110330,Recognition and association of DNA glycosylase with site containing an affected purine,55,reactome
R-HSA-110331,Cleavage of the damaged purine,55,reactome
R-HSA-171306,Packaging Of Telomere Ends,51,reactome
R-HSA-171319,Telomere Extension By Telomerase,23,reactome
R-HSA-977347,Serine metabolism,11,reactome
R-HSA-9821993,Replacement of protamines by nucleosomes in the male pronucleus,42,reactome
R-HSA-427359,SIRT1 negatively regulates rRNA expression,67,reactome
R-HSA-1059683,Interleukin-6 signaling,11,reactome
R-HSA-110056,MAPK3 (ERK1) activation,10,reactome
R-HSA-2586552,Signaling by Leptin,11,reactome
R-HSA-9027284,Erythropoietin activates RAS,14,reactome
R-HSA-982772,Growth hormone receptor signaling,24,reactome
R-HSA-75105,Fatty acyl-CoA biosynthesis,13,reactome
R-HSA-163210,Formation of ATP by chemiosmotic coupling,20,reactome
R-HSA-140875,Common Pathway of Fibrin Clot Formation,22,reactome
R-HSA-170968,Frs2-mediated activation,12,reactome
R-HSA-2559584,Formation of Senescence-Associated Heterochromatin Foci (SAHF),17,reactome
R-HSA-111367,SLBP independent Processing of Histone Pre-mRNAs,10,reactome
R-HSA-77588,SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,11,reactome
R-HSA-112409,RAF-independent MAPK1/3 activation,13,reactome
R-HSA-1181150,Signaling by NODAL,23,reactome
R-HSA-162658,Golgi Cisternae Pericentriolar Stack Reorganization,14,reactome
R-HSA-202670,ERKs are inactivated,13,reactome
R-HSA-74749,Signal attenuation,10,reactome
R-HSA-879415,Advanced glycosylation endproduct receptor signaling,13,reactome
R-HSA-9627069,Regulation of the apoptosome activity,11,reactome
R-HSA-211935,Fatty acids,15,reactome
R-HSA-211999,CYP2E1 reactions,11,reactome
R-HSA-1362409,Mitochondrial iron-sulfur cluster biogenesis,12,reactome
R-HSA-1483213,Synthesis of PE,13,reactome
R-HSA-2168880,Scavenging of heme from plasma,13,reactome
R-HSA-9020558,Interleukin-2 signaling,12,reactome
R-HSA-156711,Polo-like kinase mediated events,16,reactome
R-HSA-6804760,Regulation of TP53 Activity through Methylation,19,reactome
R-HSA-9735871,SARS-CoV-1 targets host intracellular signalling and regulatory pathways,16,reactome
R-HSA-9840309,Glycosphingolipid biosynthesis,19,reactome
R-HSA-1679131,Trafficking and processing of endosomal TLR,13,reactome
R-HSA-1855167,Synthesis of pyrophosphates in the cytosol,10,reactome
R-HSA-913709,O-linked glycosylation of mucins,54,reactome
R-HSA-74217,Purine salvage,13,reactome
R-HSA-2892247,"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation",13,reactome
R-HSA-452723,Transcriptional regulation of pluripotent stem cells,17,reactome
R-HSA-389661,Glyoxylate metabolism and glycine degradation,12,reactome
R-HSA-2691232,Constitutive Signaling by NOTCH1 HD Domain Mutants,15,reactome
R-HSA-177929,Signaling by EGFR,17,reactome
R-HSA-4419969,Depolymerization of the Nuclear Lamina,15,reactome
R-HSA-112314,Neurotransmitter receptors and postsynaptic signal transmission,10,reactome
R-HSA-446203,Asparagine N-linked glycosylation,15,reactome
R-HSA-390666,Serotonin receptors,12,reactome
R-HSA-9690406,Transcriptional regulation of testis differentiation,13,reactome
R-HSA-197264,Nicotinamide salvage,16,reactome
R-HSA-2892245,"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation",10,reactome
R-HSA-73728,RNA Polymerase I Promoter Opening,62,reactome
R-HSA-71240,Tryptophan catabolism,14,reactome
R-HSA-9020958,Interleukin-21 signaling,10,reactome
R-HSA-937039,IRAK1 recruits IKK complex,14,reactome
R-HSA-975144,IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation,14,reactome
R-HSA-442380,Zinc influx into cells by the SLC39 gene family,10,reactome
R-HSA-2465910,MASTL Facilitates Mitotic Progression,10,reactome
R-HSA-193048,Androgen biosynthesis,11,reactome
R-HSA-209822,Glycoprotein hormones,12,reactome
R-HSA-375281,Hormone ligand-binding receptors,12,reactome
R-HSA-198693,AKT phosphorylates targets in the nucleus,10,reactome
R-HSA-9614399,Regulation of localization of FOXO transcription factors,12,reactome
R-HSA-9755779,SARS-CoV-2 targets host intracellular signalling and regulatory pathways,12,reactome
R-HSA-912694,Regulation of IFNA/IFNB signaling,26,reactome
R-HSA-388844,Receptor-type tyrosine-protein phosphatases,20,reactome
R-HSA-9748787,Azathioprine ADME,23,reactome
R-HSA-5083632,Defective C1GALT1C1 causes TNPS,17,reactome
R-HSA-2151209,Activation of PPARGC1A (PGC-1alpha) by phosphorylation,10,reactome
R-HSA-9832991,Formation of the posterior neural plate,10,reactome
R-HSA-140342,Apoptosis induced DNA fragmentation,13,reactome
R-HSA-430116,GP1b-IX-V activation signalling,12,reactome
R-HSA-9700645,ALK mutants bind TKIs,12,reactome
R-HSA-75035,Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex,15,reactome
R-HSA-156588,Glucuronidation,22,reactome
R-HSA-179812,GRB2 events in EGFR signaling,13,reactome
R-HSA-180336,SHC1 events in EGFR signaling,14,reactome
R-HSA-5655291,Signaling by FGFR4 in disease,11,reactome
R-HSA-3134975,Regulation of innate immune responses to cytosolic DNA,14,reactome
R-HSA-71384,Ethanol oxidation,12,reactome
R-HSA-199220,Vitamin B5 (pantothenate) metabolism,13,reactome
R-HSA-1250342,PI3K events in ERBB4 signaling,10,reactome
R-HSA-1250347,SHC1 events in ERBB4 signaling,14,reactome
R-HSA-1963640,GRB2 events in ERBB2 signaling,16,reactome
R-HSA-1236977,Endosomal/Vacuolar pathway,11,reactome
R-HSA-5620922,BBSome-mediated cargo-targeting to cilium,23,reactome
R-HSA-1433617,Regulation of signaling by NODAL,12,reactome
R-HSA-194002,Glucocorticoid biosynthesis,10,reactome
R-HSA-5083625,Defective GALNT3 causes HFTC,16,reactome
R-HSA-167044,Signalling to RAS,10,reactome
R-HSA-9028731,Activated NTRK2 signals through FRS2 and FRS3,11,reactome
R-HSA-9664873,Pexophagy,11,reactome
R-HSA-3247509,Chromatin modifying enzymes,20,reactome
R-HSA-5083636,Defective GALNT12 causes CRCS1,16,reactome
R-HSA-373076,Class A/1 (Rhodopsin-like receptors),19,reactome
R-HSA-9013973,TICAM1-dependent activation of IRF3/IRF7,13,reactome
R-HSA-9824878,"Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 ",14,reactome
R-HSA-9828211,"Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation",11,reactome
R-HSA-975110,TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling,13,reactome
|