class_id,class_name,number_annotated,source
R-HSA-2500257,Resolution of Sister Chromatid Cohesion,127,reactome
R-HSA-5693568,Resolution of D-loop Structures through Holliday Junction Intermediates,35,reactome
R-HSA-912446,Meiotic recombination,88,reactome
R-HSA-2029481,FCGR activation,12,reactome
R-HSA-432142,Platelet sensitization by LDL,17,reactome
R-HSA-6798695,Neutrophil degranulation,478,reactome
R-HSA-9664323,FCGR3A-mediated IL10 synthesis,38,reactome
R-HSA-9664422,FCGR3A-mediated phagocytosis,59,reactome
R-HSA-977606,Regulation of Complement cascade,47,reactome
R-HSA-381426,Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs),124,reactome
R-HSA-8957275,Post-translational protein phosphorylation,107,reactome
R-HSA-174403,Glutathione synthesis and recycling,12,reactome
R-HSA-9818027,NFE2L2 regulating anti-oxidant/detoxification enzymes,19,reactome
R-HSA-1989781,PPARA activates gene expression,116,reactome
R-HSA-2426168,Activation of gene expression by SREBF (SREBP),42,reactome
R-HSA-380994,ATF4 activates genes in response to endoplasmic reticulum  stress,27,reactome
R-HSA-381183,ATF6 (ATF6-alpha) activates chaperone genes,10,reactome
R-HSA-9614657,FOXO-mediated transcription of cell death genes,16,reactome
R-HSA-5223345,Miscellaneous transport and binding events,26,reactome
R-HSA-6791226,Major pathway of rRNA processing in the nucleolus and cytosol,183,reactome
R-HSA-382556,ABC-family proteins mediated transport,68,reactome
R-HSA-5678895,Defective CFTR causes cystic fibrosis,48,reactome
R-HSA-5689880,Ub-specific processing proteases,199,reactome
R-HSA-8856825,Cargo recognition for clathrin-mediated endocytosis,105,reactome
R-HSA-8856828,Clathrin-mediated endocytosis,129,reactome
R-HSA-9013406,RHOQ GTPase cycle,59,reactome
R-HSA-9613829,Chaperone Mediated Autophagy,22,reactome
R-HSA-9615710,Late endosomal microautophagy,34,reactome
R-HSA-9646399,Aggrephagy,44,reactome
R-HSA-9925563,Developmental Lineage of Pancreatic Ductal Cells,48,reactome
R-HSA-191273,Cholesterol biosynthesis,24,reactome
R-HSA-211976,Endogenous sterols,24,reactome
R-HSA-9619665,EGR2 and SOX10-mediated initiation of Schwann cell myelination,29,reactome
R-HSA-3108214,SUMOylation of DNA damage response and repair proteins,77,reactome
R-HSA-5685938,HDR through Single Strand Annealing (SSA),37,reactome
R-HSA-5685939,HDR through MMEJ (alt-NHEJ),12,reactome
R-HSA-111447,Activation of BAD and translocation to mitochondria ,15,reactome
R-HSA-193648,NRAGE signals death through JNK,59,reactome
R-HSA-198323,AKT phosphorylates targets in the cytosol,14,reactome
R-HSA-5674400,Constitutive Signaling by AKT1 E17K in Cancer,26,reactome
R-HSA-198933,Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell,132,reactome
R-HSA-202733,Cell surface interactions at the vascular wall,87,reactome
R-HSA-2022928,HS-GAG biosynthesis,31,reactome
R-HSA-211945,Phase I - Functionalization of compounds,22,reactome
R-HSA-3238698,WNT ligand biogenesis and trafficking,26,reactome
R-HSA-373080,Class B/2 (Secretin family receptors),51,reactome
R-HSA-4641258,Degradation of DVL,44,reactome
R-HSA-141444,Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal,94,reactome
R-HSA-2467813,Separation of Sister Chromatids,178,reactome
R-HSA-5663220,RHO GTPases Activate Formins,140,reactome
R-HSA-68877,Mitotic Prometaphase,113,reactome
R-HSA-9648025,EML4 and NUDC in mitotic spindle formation,117,reactome
R-HSA-432720,Lysosome Vesicle Biogenesis,35,reactome
R-HSA-6811440,Retrograde transport at the Trans-Golgi-Network,49,reactome
R-HSA-9840310,Glycosphingolipid catabolism,39,reactome
R-HSA-8951664,Neddylation,232,reactome
R-HSA-983168,Antigen processing: Ubiquitination & Proteasome degradation,295,reactome
R-HSA-5365859,RA biosynthesis pathway,22,reactome
R-HSA-8876198,RAB GEFs exchange GTP for GDP on RABs,90,reactome
R-HSA-9013149,RAC1 GTPase cycle,184,reactome
R-HSA-6803207,TP53 Regulates Transcription of Caspase Activators and Caspases,12,reactome
R-HSA-933543,NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10,13,reactome
R-HSA-3371378,Regulation by c-FLIP,11,reactome
R-HSA-5213460,RIPK1-mediated regulated necrosis,22,reactome
R-HSA-5218900,CASP8 activity is inhibited,11,reactome
R-HSA-5357905,Regulation of TNFR1 signaling,48,reactome
R-HSA-69416,Dimerization of procaspase-8,11,reactome
R-HSA-6799198,Complex I biogenesis,68,reactome
R-HSA-72163,mRNA Splicing - Major Pathway,204,reactome
R-HSA-1660517,Synthesis of PIPs at the late endosome membrane,11,reactome
R-HSA-1855183,"Synthesis of IP2, IP, and Ins in the cytosol",14,reactome
R-HSA-352230,Amino acid transport across the plasma membrane,33,reactome
R-HSA-6807878,COPI-mediated anterograde transport,102,reactome
R-HSA-6811434,COPI-dependent Golgi-to-ER retrograde traffic,100,reactome
R-HSA-936964,"Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)",18,reactome
R-HSA-937041,IKK complex recruitment mediated by RIP1,23,reactome
R-HSA-937072,TRAF6-mediated induction of TAK1 complex within TLR4 complex,16,reactome
R-HSA-416700,Other semaphorin interactions,19,reactome
R-HSA-9013508,NOTCH3 Intracellular Domain Regulates Transcription,25,reactome
R-HSA-9696270,RND2 GTPase cycle,43,reactome
R-HSA-499943,Interconversion of nucleotide di- and triphosphates,29,reactome
R-HSA-196807,Nicotinate metabolism,13,reactome
R-HSA-3371453,Regulation of HSF1-mediated heat shock response,82,reactome
R-HSA-3371497,HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand,57,reactome
R-HSA-3371511,HSF1 activation,31,reactome
R-HSA-3371568,Attenuation phase,28,reactome
R-HSA-3371571,HSF1-dependent transactivation,34,reactome
R-HSA-8939211,ESR-mediated signaling,11,reactome
R-HSA-9018519,Estrogen-dependent gene expression,149,reactome
R-HSA-9679191,Potential therapeutics for SARS,98,reactome
R-HSA-3214815,HDACs deacetylate histones,94,reactome
R-HSA-3214842,HDMs demethylate histones,50,reactome
R-HSA-5625886,Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3,66,reactome
R-HSA-8943724,Regulation of PTEN gene transcription,61,reactome
R-HSA-9029569,NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux,37,reactome
R-HSA-983231,Factors involved in megakaryocyte development and platelet production,109,reactome
R-HSA-111932,CaMK IV-mediated phosphorylation of CREB,10,reactome
R-HSA-9013148,CDC42 GTPase cycle,155,reactome
R-HSA-611105,Respiratory electron transport,88,reactome
R-HSA-77289,Mitochondrial Fatty Acid Beta-Oxidation,19,reactome
R-HSA-9857492,Protein lipoylation,10,reactome
R-HSA-204174,Regulation of pyruvate dehydrogenase (PDH) complex,15,reactome
R-HSA-5362517,Signaling by Retinoic Acid,19,reactome
R-HSA-9841922,MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis,134,reactome
R-HSA-549127,Organic cation transport,10,reactome
R-HSA-1268020,Mitochondrial protein import,65,reactome
R-HSA-8963693,Aspartate and asparagine metabolism,11,reactome
R-HSA-141430,Inactivation of APC/C via direct inhibition of the APC/C complex,21,reactome
R-HSA-174048,APC/C:Cdc20 mediated degradation of Cyclin B,24,reactome
R-HSA-174084,Autodegradation of Cdh1 by Cdh1:APC/C,54,reactome
R-HSA-174154,APC/C:Cdc20 mediated degradation of Securin,55,reactome
R-HSA-174178,APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1,61,reactome
R-HSA-174184,Cdc20:Phospho-APC/C mediated degradation of Cyclin A,60,reactome
R-HSA-176407,Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase,20,reactome
R-HSA-176408,Regulation of APC/C activators between G1/S and early anaphase,25,reactome
R-HSA-176409,APC/C:Cdc20 mediated degradation of mitotic proteins,21,reactome
R-HSA-176412,Phosphorylation of the APC/C,20,reactome
R-HSA-179409,APC-Cdc20 mediated degradation of Nek2A,26,reactome
R-HSA-2559582,Senescence-Associated Secretory Phenotype (SASP),111,reactome
R-HSA-68867,Assembly of the pre-replicative complex,69,reactome
R-HSA-69017,CDK-mediated phosphorylation and removal of Cdc6,60,reactome
R-HSA-8853884,Transcriptional Regulation by VENTX,39,reactome
R-HSA-9687136,Aberrant regulation of mitotic exit in cancer due to RB1 defects,20,reactome
R-HSA-1237044,Erythrocytes take up carbon dioxide and release oxygen,13,reactome
R-HSA-425381,Bicarbonate transporters,10,reactome
R-HSA-418555,G alpha (s) signalling events,145,reactome
R-HSA-419812,Calcitonin-like ligand receptors,10,reactome
R-HSA-201681,TCF dependent signaling in response to WNT,36,reactome
R-HSA-2028269,Signaling by Hippo,20,reactome
R-HSA-4086400,PCP/CE pathway,21,reactome
R-HSA-4608870,Asymmetric localization of PCP proteins,51,reactome
R-HSA-4641262,Disassembly of the destruction complex and recruitment of AXIN to the membrane,31,reactome
R-HSA-5099900,WNT5A-dependent internalization of FZD4,15,reactome
R-HSA-9673324,WNT5:FZD7-mediated leishmania damping,12,reactome
R-HSA-975956,Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC),96,reactome
R-HSA-975957,Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC),116,reactome
R-HSA-391160,Signal regulatory protein family interactions,16,reactome
R-HSA-83936,Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane,12,reactome
R-HSA-9837999,Mitochondrial protein degradation,98,reactome
R-HSA-8949215,Mitochondrial calcium ion transport,13,reactome
R-HSA-8949664,Processing of SMDT1,16,reactome
R-HSA-9830674,Formation of the ureteric bud,21,reactome
R-HSA-112382,Formation of RNA Pol II elongation complex ,58,reactome
R-HSA-113418,Formation of the Early Elongation Complex,33,reactome
R-HSA-167152,Formation of HIV elongation complex in the absence of HIV Tat,45,reactome
R-HSA-167158,Formation of the HIV-1 Early Elongation Complex,33,reactome
R-HSA-167160,RNA Pol II CTD phosphorylation and interaction with CE during HIV infection,27,reactome
R-HSA-167161,HIV Transcription Initiation,47,reactome
R-HSA-167162,RNA Polymerase II HIV Promoter Escape,47,reactome
R-HSA-167172,Transcription of the HIV genome,47,reactome
R-HSA-167200,Formation of HIV-1 elongation complex containing HIV-1 Tat,43,reactome
R-HSA-167238,Pausing and recovery of Tat-mediated HIV elongation,31,reactome
R-HSA-167242,Abortive elongation of HIV-1 transcript in the absence of Tat,23,reactome
R-HSA-167243,Tat-mediated HIV elongation arrest and recovery,31,reactome
R-HSA-167246,Tat-mediated elongation of the HIV-1 transcript,41,reactome
R-HSA-167287,HIV elongation arrest and recovery,33,reactome
R-HSA-167290,Pausing and recovery of HIV elongation,33,reactome
R-HSA-168325,Viral Messenger RNA Synthesis,44,reactome
R-HSA-203927,MicroRNA (miRNA) biogenesis,24,reactome
R-HSA-5578749,Transcriptional regulation by small RNAs,106,reactome
R-HSA-5601884,PIWI-interacting RNA (piRNA) biogenesis,29,reactome
R-HSA-5617472,Activation of anterior HOX genes in hindbrain development during early embryogenesis,122,reactome
R-HSA-674695,RNA Polymerase II Pre-transcription Events,81,reactome
R-HSA-6781823,Formation of TC-NER Pre-Incision Complex,51,reactome
R-HSA-6781827,Transcription-Coupled Nucleotide Excision Repair (TC-NER),42,reactome
R-HSA-6782135,Dual incision in TC-NER,63,reactome
R-HSA-6782210,Gap-filling DNA repair synthesis and ligation in TC-NER,62,reactome
R-HSA-6796648,TP53 Regulates Transcription of DNA Repair Genes,62,reactome
R-HSA-6803529,FGFR2 alternative splicing,27,reactome
R-HSA-6807505,RNA polymerase II transcribes snRNA genes,74,reactome
R-HSA-72086,mRNA Capping,29,reactome
R-HSA-72165,mRNA Splicing - Minor Pathway,50,reactome
R-HSA-72203,Processing of Capped Intron-Containing Pre-mRNA,70,reactome
R-HSA-73776,RNA Polymerase II Promoter Escape,47,reactome
R-HSA-73779,RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,47,reactome
R-HSA-75953,RNA Polymerase II Transcription Initiation,47,reactome
R-HSA-75955,RNA Polymerase II Transcription Elongation,56,reactome
R-HSA-76042,RNA Polymerase II Transcription Initiation And Promoter Clearance,47,reactome
R-HSA-77075,RNA Pol II CTD phosphorylation and interaction with CE,27,reactome
R-HSA-8851708,Signaling by FGFR2 IIIa TM,19,reactome
R-HSA-9670095,Inhibition of DNA recombination at telomere,67,reactome
R-HSA-5083635,Defective B3GALTL causes PpS,37,reactome
R-HSA-5173214,O-glycosylation of TSR domain-containing proteins,38,reactome
R-HSA-5696397,Gap-filling DNA repair synthesis and ligation in GG-NER,25,reactome
R-HSA-9913635,Strand-asynchronous mitochondrial DNA replication,10,reactome
R-HSA-2564830,Cytosolic iron-sulfur cluster assembly,13,reactome
R-HSA-163615,PKA activation,18,reactome
R-HSA-164378,PKA activation in glucagon signalling,17,reactome
R-HSA-180024,DARPP-32 events,24,reactome
R-HSA-2565942,Regulation of PLK1 Activity at G2/M Transition,87,reactome
R-HSA-380259,Loss of Nlp from mitotic centrosomes,69,reactome
R-HSA-380270,Recruitment of mitotic centrosome proteins and complexes,81,reactome
R-HSA-380284,Loss of proteins required for interphase microtubule organization from the centrosome,69,reactome
R-HSA-380320,Recruitment of NuMA to mitotic centrosomes,95,reactome
R-HSA-381676,Glucagon-like Peptide-1 (GLP1) regulates insulin secretion,42,reactome
R-HSA-432040,Vasopressin regulates renal water homeostasis via Aquaporins,43,reactome
R-HSA-442720,CREB1 phosphorylation through the activation of Adenylate Cyclase,12,reactome
R-HSA-5610787,Hedgehog 'off' state,56,reactome
R-HSA-5620912,Anchoring of the basal body to the plasma membrane,97,reactome
R-HSA-8854518,AURKA Activation by TPX2,72,reactome
R-HSA-9634597,GPER1 signaling,45,reactome
R-HSA-9660821,ADORA2B mediated anti-inflammatory cytokines production,43,reactome
R-HSA-9856530,High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells,69,reactome
R-HSA-3214847,HATs acetylate histones,142,reactome
R-HSA-1234158,Regulation of gene expression by Hypoxia-inducible Factor,11,reactome
R-HSA-1368108,"BMAL1:CLOCK,NPAS2 activates circadian expression",26,reactome
R-HSA-1912408,Pre-NOTCH Transcription and Translation,92,reactome
R-HSA-201722,Formation of the beta-catenin:TCF transactivating complex,89,reactome
R-HSA-210744,Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells,16,reactome
R-HSA-2122947,NOTCH1 Intracellular Domain Regulates Transcription,48,reactome
R-HSA-2151201,Transcriptional activation of mitochondrial biogenesis,55,reactome
R-HSA-2644606,Constitutive Signaling by NOTCH1 PEST Domain Mutants,58,reactome
R-HSA-2894862,Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants,58,reactome
R-HSA-350054,Notch-HLH transcription pathway,28,reactome
R-HSA-381340,Transcriptional regulation of white adipocyte differentiation,84,reactome
R-HSA-3899300,SUMOylation of transcription cofactors,44,reactome
R-HSA-400206,Regulation of lipid metabolism by PPARalpha,20,reactome
R-HSA-5621575,CD209 (DC-SIGN) signaling,21,reactome
R-HSA-6803204,TP53 Regulates Transcription of Genes Involved in Cytochrome C Release,20,reactome
R-HSA-8866907,Activation of the TFAP2 (AP-2) family of transcription factors,12,reactome
R-HSA-8941856,RUNX3 regulates NOTCH signaling,14,reactome
R-HSA-9013695,NOTCH4 Intracellular Domain Regulates Transcription,20,reactome
R-HSA-918233,TRAF3-dependent IRF activation pathway,15,reactome
R-HSA-933541,TRAF6 mediated IRF7 activation,30,reactome
R-HSA-9617629,Regulation of FOXO transcriptional activity by acetylation,10,reactome
R-HSA-9705671,SARS-CoV-2 activates/modulates innate and adaptive immune responses,126,reactome
R-HSA-9707564,Cytoprotection by HMOX1,56,reactome
R-HSA-9707616,Heme signaling,49,reactome
R-HSA-9768919,NPAS4 regulates expression of target genes,22,reactome
R-HSA-9793380,Formation of paraxial mesoderm,22,reactome
R-HSA-9818030,NFE2L2 regulating tumorigenic genes,11,reactome
R-HSA-9819196,Zygotic genome activation (ZGA),17,reactome
R-HSA-9833109,Evasion by RSV of host interferon responses,35,reactome
R-HSA-9856649,Transcriptional and post-translational regulation of MITF-M expression and activity,62,reactome
R-HSA-9931509,"Expression of BMAL (ARNTL), CLOCK, and NPAS2",36,reactome
R-HSA-9931510,Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes,22,reactome
R-HSA-9931512,"Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters",11,reactome
R-HSA-9931521,The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex,14,reactome
R-HSA-9933387,"RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression",26,reactome
R-HSA-181429,Serotonin Neurotransmitter Release Cycle,18,reactome
R-HSA-181430,Norepinephrine Neurotransmitter Release Cycle,18,reactome
R-HSA-196108,Pregnenolone biosynthesis,12,reactome
R-HSA-210500,Glutamate Neurotransmitter Release Cycle,24,reactome
R-HSA-212676,Dopamine Neurotransmitter Release Cycle,23,reactome
R-HSA-264642,Acetylcholine Neurotransmitter Release Cycle,17,reactome
R-HSA-9033241,Peroxisomal protein import,63,reactome
R-HSA-212436,Generic Transcription Pathway,350,reactome
R-HSA-390471,Association of TriC/CCT with target proteins during biosynthesis,39,reactome
R-HSA-9932298,Degradation of CRY and PER proteins,48,reactome
R-HSA-216083,Integrin cell surface interactions,85,reactome
R-HSA-210991,Basigin interactions,25,reactome
R-HSA-3000157,Laminin interactions,30,reactome
R-HSA-8874081,MET activates PTK2 signaling,30,reactome
R-HSA-114608,Platelet degranulation ,127,reactome
R-HSA-3000178,ECM proteoglycans,76,reactome
R-HSA-354192,Integrin signaling,23,reactome
R-HSA-354194,GRB2:SOS provides linkage to MAPK signaling for Integrins ,15,reactome
R-HSA-372708,p130Cas linkage to MAPK signaling for integrins,15,reactome
R-HSA-445144,Signal transduction by L1,21,reactome
R-HSA-5674135,MAP2K and MAPK activation,40,reactome
R-HSA-6802946,Signaling by moderate kinase activity BRAF mutants,45,reactome
R-HSA-6802948,Signaling by high-kinase activity BRAF mutants,36,reactome
R-HSA-6802952,Signaling by BRAF and RAF1 fusions,65,reactome
R-HSA-6802955,Paradoxical activation of RAF signaling by kinase inactive BRAF,45,reactome
R-HSA-8936459,RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function,95,reactome
R-HSA-9649948,Signaling downstream of RAS mutants,45,reactome
R-HSA-9656223,Signaling by RAF1 mutants,41,reactome
R-HSA-6788467,IL-6-type cytokine receptor ligand interactions,17,reactome
R-HSA-9020956,Interleukin-27 signaling,11,reactome
R-HSA-192105,Synthesis of bile acids and bile salts,14,reactome
R-HSA-6805567,Keratinization,155,reactome
R-HSA-6809371,Formation of the cornified envelope,129,reactome
R-HSA-389357,CD28 dependent PI3K/Akt signaling,27,reactome
R-HSA-5607761,Dectin-1 mediated noncanonical NF-kB signaling,49,reactome
R-HSA-5668541,TNFR2 non-canonical NF-kB pathway,55,reactome
R-HSA-5676590,NIK-->noncanonical NF-kB signaling,46,reactome
R-HSA-5676594,TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway,17,reactome
R-HSA-422356,Regulation of insulin secretion,28,reactome
R-HSA-399719,Trafficking of AMPA receptors,17,reactome
R-HSA-5682910,LGI-ADAM interactions,14,reactome
R-HSA-177504,Retrograde neurotrophin signalling,14,reactome
R-HSA-2132295,MHC class II antigen presentation,126,reactome
R-HSA-3928665,EPH-ephrin mediated repulsion of cells,51,reactome
R-HSA-416993,Trafficking of GluR2-containing AMPA receptors,17,reactome
R-HSA-437239,Recycling pathway of L1,49,reactome
R-HSA-5140745,"WNT5A-dependent internalization of FZD2, FZD5 and ROR2",13,reactome
R-HSA-8866427,VLDLR internalisation and degradation,16,reactome
R-HSA-8964038,LDL clearance,19,reactome
R-HSA-416476,G alpha (q) signalling events,174,reactome
R-HSA-380108,Chemokine receptors bind chemokines,57,reactome
R-HSA-418594,G alpha (i) signalling events,258,reactome
R-HSA-419037,NCAM1 interactions,42,reactome
R-HSA-445355,Smooth Muscle Contraction,43,reactome
R-HSA-8939902,Regulation of RUNX2 expression and activity,59,reactome
R-HSA-1445148,Translocation of SLC2A4 (GLUT4) to the plasma membrane,72,reactome
R-HSA-171007,p38MAPK events,13,reactome
R-HSA-8950505,Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation,38,reactome
R-HSA-9013404,RAC2 GTPase cycle,88,reactome
R-HSA-9013423,RAC3 GTPase cycle,94,reactome
R-HSA-9035034,RHOF GTPase cycle,42,reactome
R-HSA-9845614,Sphingolipid catabolism,12,reactome
R-HSA-399955,SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion,14,reactome
R-HSA-9662360,Sensory processing of sound by inner hair cells of the cochlea,69,reactome
R-HSA-9662361,Sensory processing of sound by outer hair cells of the cochlea,50,reactome
R-HSA-176187,Activation of ATR in response to replication stress,37,reactome
R-HSA-68962,Activation of the pre-replicative complex,33,reactome
R-HSA-416482,G alpha (12/13) signalling events,80,reactome
R-HSA-428930,Thromboxane signalling through TP receptor,24,reactome
R-HSA-189451,Heme biosynthesis,14,reactome
R-HSA-8866654,E3 ubiquitin ligases ubiquitinate target proteins,59,reactome
R-HSA-9754560,SARS-CoV-2 modulates autophagy,11,reactome
R-HSA-8980692,RHOA GTPase cycle,149,reactome
R-HSA-6784531,tRNA processing in the nucleus,58,reactome
R-HSA-1663150,The activation of arylsulfatases,13,reactome
R-HSA-163560,Triglyceride catabolism,24,reactome
R-HSA-73614,Pyrimidine salvage,11,reactome
R-HSA-73621,Pyrimidine catabolism,12,reactome
R-HSA-163125,Post-translational modification: synthesis of GPI-anchored proteins,66,reactome
R-HSA-6811436,COPI-independent Golgi-to-ER retrograde traffic,53,reactome
R-HSA-1222556,ROS and RNS production in phagocytes,34,reactome
R-HSA-6785807,Interleukin-4 and Interleukin-13 signaling,108,reactome
R-HSA-204005,COPII-mediated vesicle transport,69,reactome
R-HSA-8863795,Downregulation of ERBB2 signaling,24,reactome
R-HSA-983695,Antigen activates B Cell Receptor (BCR) leading to generation of second messengers,29,reactome
R-HSA-445095,Interaction between L1 and Ankyrins,31,reactome
R-HSA-5576892,Phase 0 - rapid depolarisation,32,reactome
R-HSA-210745,Regulation of gene expression in beta cells,18,reactome
R-HSA-381771,"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)",21,reactome
R-HSA-400511,"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)",13,reactome
R-HSA-9823739,Formation of the anterior neural plate,11,reactome
R-HSA-112308,Presynaptic depolarization and calcium channel opening,11,reactome
R-HSA-400042,"Adrenaline,noradrenaline inhibits insulin secretion",28,reactome
R-HSA-5576893,Phase 2 - plateau phase,15,reactome
R-HSA-6790901,rRNA modification in the nucleus and cytosol,60,reactome
R-HSA-162710,Synthesis of glycosylphosphatidylinositol (GPI),18,reactome
R-HSA-2032785,YAP1- and WWTR1 (TAZ)-stimulated gene expression,15,reactome
R-HSA-8949613,Cristae formation,33,reactome
R-HSA-5668599,RHO GTPases Activate NADPH Oxidases,24,reactome
R-HSA-2559580,Oxidative Stress Induced Senescence,123,reactome
R-HSA-2559585,Oncogene Induced Senescence,33,reactome
R-HSA-69231,Cyclin D associated events in G1,47,reactome
R-HSA-9661069,"Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)",17,reactome
R-HSA-1169091,Activation of NF-kappaB in B cells,54,reactome
R-HSA-1234176,Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha,53,reactome
R-HSA-1236974,ER-Phagosome pathway,82,reactome
R-HSA-1236978,Cross-presentation of soluble exogenous antigens (endosomes),41,reactome
R-HSA-174113,SCF-beta-TrCP mediated degradation of Emi1,42,reactome
R-HSA-180534,Vpu mediated degradation of CD4,39,reactome
R-HSA-180585,Vif-mediated degradation of APOBEC3G,41,reactome
R-HSA-187577,SCF(Skp2)-mediated degradation of p27/p21,50,reactome
R-HSA-195253,Degradation of beta-catenin by the destruction complex,56,reactome
R-HSA-202424,Downstream TCR signaling,84,reactome
R-HSA-211733,Regulation of activated PAK-2p34 by proteasome mediated degradation,37,reactome
R-HSA-2871837,FCERI mediated NF-kB activation,68,reactome
R-HSA-349425,Autodegradation of the E3 ubiquitin ligase COP1,39,reactome
R-HSA-350562,Regulation of ornithine decarboxylase (ODC),38,reactome
R-HSA-450408,AUF1 (hnRNP D0) binds and destabilizes mRNA,42,reactome
R-HSA-4641257,Degradation of AXIN,42,reactome
R-HSA-5358346,Hedgehog ligand biogenesis,47,reactome
R-HSA-5362768,Hh mutants are degraded by ERAD,43,reactome
R-HSA-5607764,CLEC7A (Dectin-1) signaling,66,reactome
R-HSA-5610780,Degradation of GLI1 by the proteasome,47,reactome
R-HSA-5610783,Degradation of GLI2 by the proteasome,47,reactome
R-HSA-5610785,GLI3 is processed to GLI3R by the proteasome,47,reactome
R-HSA-5632684,Hedgehog 'on' state,60,reactome
R-HSA-5658442,Regulation of RAS by GAPs,55,reactome
R-HSA-5687128,MAPK6/MAPK4 signaling,78,reactome
R-HSA-5689603,UCH proteinases,88,reactome
R-HSA-68949,Orc1 removal from chromatin,58,reactome
R-HSA-69481,G2/M Checkpoints,38,reactome
R-HSA-69601,Ubiquitin Mediated Degradation of Phosphorylated Cdc25A,39,reactome
R-HSA-75815,Ubiquitin-dependent degradation of Cyclin D,39,reactome
R-HSA-8852276,The role of GTSE1 in G2/M progression after G2 checkpoint,66,reactome
R-HSA-8854050,FBXL7 down-regulates AURKA during mitotic entry and in early mitosis,42,reactome
R-HSA-8939236,RUNX1 regulates transcription of genes involved in differentiation of HSCs,116,reactome
R-HSA-8941858,Regulation of RUNX3 expression and activity,45,reactome
R-HSA-8948751,Regulation of PTEN stability and activity,56,reactome
R-HSA-9010553,Regulation of expression of SLITs and ROBOs,159,reactome
R-HSA-9020702,Interleukin-1 signaling,74,reactome
R-HSA-9604323,Negative regulation of NOTCH4 signaling,44,reactome
R-HSA-9755511,KEAP1-NFE2L2 pathway,64,reactome
R-HSA-9762114,GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2,42,reactome
R-HSA-9824272,Somitogenesis,45,reactome
R-HSA-9907900,Proteasome assembly,52,reactome
R-HSA-9912633,"Antigen processing: Ub, ATP-independent proteasomal degradation",19,reactome
R-HSA-212300,PRC2 methylates histones and DNA,72,reactome
R-HSA-3232118,SUMOylation of transcription factors,20,reactome
R-HSA-8866904,Negative regulation of activity of TFAP2 (AP-2) family transcription factors,10,reactome
R-HSA-8866910,TFAP2 (AP-2) family regulates transcription of growth factors and their receptors,15,reactome
R-HSA-9834899,Specification of the neural plate border,17,reactome
R-HSA-6811438,Intra-Golgi traffic,44,reactome
R-HSA-525793,Myogenesis,29,reactome
R-HSA-156590,Glutathione conjugation,24,reactome
R-HSA-5423646,Aflatoxin activation and detoxification,18,reactome
R-HSA-9931530,Phosphorylation and nuclear translocation of the CRY:PER:kinase complex,14,reactome
R-HSA-6803157,Antimicrobial peptides,38,reactome
R-HSA-73980,RNA Polymerase III Transcription Termination,23,reactome
R-HSA-749476,RNA Polymerase III Abortive And Retractive Initiation,41,reactome
R-HSA-2022854,Keratan sulfate biosynthesis,28,reactome
R-HSA-4085001,Sialic acid metabolism,33,reactome
R-HSA-9694548,Maturation of spike protein,41,reactome
R-HSA-977068,Termination of O-glycan biosynthesis,23,reactome
R-HSA-1592389,Activation of Matrix Metalloproteinases,33,reactome
R-HSA-449836,Other interleukin signaling,24,reactome
R-HSA-5620916,VxPx cargo-targeting to cilium,21,reactome
R-HSA-9833110,RSV-host interactions,65,reactome
R-HSA-9013418,RHOBTB2 GTPase cycle,23,reactome
R-HSA-156827,L13a-mediated translational silencing of Ceruloplasmin expression,112,reactome
R-HSA-156902,Peptide chain elongation,90,reactome
R-HSA-1799339,SRP-dependent cotranslational protein targeting to membrane,113,reactome
R-HSA-192823,Viral mRNA Translation,90,reactome
R-HSA-2408557,Selenocysteine synthesis,94,reactome
R-HSA-72649,Translation initiation complex formation,59,reactome
R-HSA-72689,Formation of a pool of free 40S subunits,102,reactome
R-HSA-72695,"Formation of the ternary complex, and subsequently, the 43S complex",52,reactome
R-HSA-72702,Ribosomal scanning and start codon recognition,59,reactome
R-HSA-72706,GTP hydrolysis and joining of the 60S ribosomal subunit,113,reactome
R-HSA-72764,Eukaryotic Translation Termination,94,reactome
R-HSA-9633012,Response of EIF2AK4 (GCN2) to amino acid deficiency,102,reactome
R-HSA-9735869,SARS-CoV-1 modulates host translation machinery,37,reactome
R-HSA-9754678,SARS-CoV-2 modulates host translation machinery,50,reactome
R-HSA-110312,Translesion synthesis by REV1,16,reactome
R-HSA-5655862,Translesion synthesis by POLK,17,reactome
R-HSA-5656121,Translesion synthesis by POLI,17,reactome
R-HSA-166663,Initial triggering of complement,17,reactome
R-HSA-5173105,O-linked glycosylation,15,reactome
R-HSA-162588,Budding and maturation of HIV virion,28,reactome
R-HSA-917729,Endosomal Sorting Complex Required For Transport (ESCRT),31,reactome
R-HSA-5250924,B-WICH complex positively regulates rRNA expression,90,reactome
R-HSA-5693565,Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks,77,reactome
R-HSA-373760,L1CAM interactions,13,reactome
R-HSA-5673001,RAF/MAP kinase cascade,131,reactome
R-HSA-8851805,MET activates RAS signaling,11,reactome
R-HSA-9861718,Regulation of pyruvate metabolism,18,reactome
R-HSA-110320,Translesion Synthesis by POLH,19,reactome
R-HSA-9865881,Complex III assembly,26,reactome
R-HSA-2514853,Condensation of Prometaphase Chromosomes,11,reactome
R-HSA-420092,Glucagon-type ligand receptors,33,reactome
R-HSA-9696264,RND3 GTPase cycle,42,reactome
R-HSA-442660,Na+/Cl- dependent neurotransmitter transporters,19,reactome
R-HSA-2024096,HS-GAG degradation,24,reactome
R-HSA-2024101,CS/DS degradation,14,reactome
R-HSA-1462054,Alpha-defensins,10,reactome
R-HSA-9725554,Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin,39,reactome
R-HSA-9758881,Uptake of dietary cobalamins into enterocytes,10,reactome
R-HSA-202427,Phosphorylation of CD3 and TCR zeta chains,22,reactome
R-HSA-202430,Translocation of ZAP-70 to Immunological synapse,19,reactome
R-HSA-202433,Generation of second messenger molecules,34,reactome
R-HSA-389948,Co-inhibition by PD-1,23,reactome
R-HSA-166058,MyD88:MAL(TIRAP) cascade initiated on plasma membrane,26,reactome
R-HSA-2029482,Regulation of actin dynamics for phagocytic cup formation,61,reactome
R-HSA-2424491,DAP12 signaling,29,reactome
R-HSA-2871809,FCERI mediated Ca+2 mobilization,31,reactome
R-HSA-5602498,MyD88 deficiency (TLR2/4),17,reactome
R-HSA-5603041,IRAK4 deficiency (TLR2/4),18,reactome
R-HSA-5663213,RHO GTPases Activate WASPs and WAVEs,36,reactome
R-HSA-8964315,G beta:gamma signalling through BTK,18,reactome
R-HSA-917977,Transferrin endocytosis and recycling,31,reactome
R-HSA-4551638,SUMOylation of chromatin organization proteins,71,reactome
R-HSA-4570464,SUMOylation of RNA binding proteins,47,reactome
R-HSA-4655427,SUMOylation of DNA methylation proteins,16,reactome
R-HSA-8939243,RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known,37,reactome
R-HSA-114604,GPVI-mediated activation cascade,35,reactome
R-HSA-1227986,Signaling by ERBB2,18,reactome
R-HSA-1257604,PIP3 activates AKT signaling,105,reactome
R-HSA-1433557,Signaling by SCF-KIT,37,reactome
R-HSA-1433559,Regulation of KIT signaling,16,reactome
R-HSA-210990,PECAM1 interactions,12,reactome
R-HSA-2219530,Constitutive Signaling by Aberrant PI3K in Cancer,86,reactome
R-HSA-2682334,EPH-Ephrin signaling,26,reactome
R-HSA-2730905,Role of LAT2/NTAL/LAB on calcium mobilization,16,reactome
R-HSA-373753,Nephrin family interactions,23,reactome
R-HSA-375165,NCAM signaling for neurite out-growth,22,reactome
R-HSA-389356,Co-stimulation by CD28,19,reactome
R-HSA-389359,CD28 dependent Vav1 pathway,12,reactome
R-HSA-389513,Co-inhibition by CTLA4,21,reactome
R-HSA-3928662,EPHB-mediated forward signaling,42,reactome
R-HSA-3928663,EPHA-mediated growth cone collapse,29,reactome
R-HSA-3928664,Ephrin signaling,19,reactome
R-HSA-399954,Sema3A PAK dependent Axon repulsion,16,reactome
R-HSA-399956,CRMPs in Sema3A signaling,16,reactome
R-HSA-418885,DCC mediated attractive signaling,14,reactome
R-HSA-4420097,VEGFA-VEGFR2 Pathway,62,reactome
R-HSA-5621480,Dectin-2 family,26,reactome
R-HSA-6811558,"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling",114,reactome
R-HSA-75892,Platelet Adhesion to exposed collagen,16,reactome
R-HSA-912631,Regulation of signaling by CBL,22,reactome
R-HSA-9670439,"Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants",20,reactome
R-HSA-9680350,Signaling by CSF1 (M-CSF) in myeloid cells,31,reactome
R-HSA-1614558,Degradation of cysteine and homocysteine,10,reactome
R-HSA-2672351,Stimuli-sensing channels,78,reactome
R-HSA-71288,Creatine metabolism,10,reactome
R-HSA-6794361,Neurexins and neuroligins,56,reactome
R-HSA-190373,FGFR1c ligand binding and activation,14,reactome
R-HSA-5654726,Negative regulation of FGFR1 signaling,26,reactome
R-HSA-9772755,Formation of WDR5-containing histone-modifying complexes,42,reactome
R-HSA-936440,Negative regulators of DDX58/IFIH1 signaling,35,reactome
R-HSA-9824585,Regulation of MITF-M-dependent genes involved in pigmentation,42,reactome
R-HSA-9845323,Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs),97,reactome
R-HSA-9933937,Formation of the canonical BAF (cBAF) complex,18,reactome
R-HSA-9934037,Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF),25,reactome
R-HSA-379726,Mitochondrial tRNA aminoacylation,21,reactome
R-HSA-1660499,Synthesis of PIPs at the plasma membrane,53,reactome
R-HSA-1660514,Synthesis of PIPs at the Golgi membrane,18,reactome
R-HSA-1660516,Synthesis of PIPs at the early endosome membrane,16,reactome
R-HSA-432722,Golgi Associated Vesicle Biogenesis,56,reactome
R-HSA-75205,Dissolution of Fibrin Clot,13,reactome
R-HSA-9013026,RHOB GTPase cycle,70,reactome
R-HSA-9013106,RHOC GTPase cycle,74,reactome
R-HSA-8854214,TBC/RABGAPs,44,reactome
R-HSA-1474228,Degradation of the extracellular matrix,81,reactome
R-HSA-1971475,A tetrasaccharide linker sequence is required for GAG synthesis,27,reactome
R-HSA-2022870,Chondroitin sulfate biosynthesis,20,reactome
R-HSA-2022923,Dermatan sulfate biosynthesis,11,reactome
R-HSA-3560783,"Defective B4GALT7 causes EDS, progeroid type",20,reactome
R-HSA-3560801,Defective B3GAT3 causes JDSSDHD,20,reactome
R-HSA-4420332,Defective B3GALT6 causes EDSP2 and SEMDJL1,20,reactome
R-HSA-5675221,Negative regulation of MAPK pathway,41,reactome
R-HSA-2172127,DAP12 interactions,24,reactome
R-HSA-977443,GABA receptor activation,17,reactome
R-HSA-1221632,Meiotic synapsis,78,reactome
R-HSA-5685942,HDR through Homologous Recombination (HRR),49,reactome
R-HSA-5689901,Metalloprotease DUBs,37,reactome
R-HSA-5693554,Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA),27,reactome
R-HSA-5693571,Nonhomologous End-Joining (NHEJ),68,reactome
R-HSA-5693579,Homologous DNA Pairing and Strand Exchange,26,reactome
R-HSA-5693607,Processing of DNA double-strand break ends,97,reactome
R-HSA-5693616,Presynaptic phase of homologous DNA pairing and strand exchange,40,reactome
R-HSA-6804756,Regulation of TP53 Activity through Phosphorylation,92,reactome
R-HSA-69473,G2/M DNA damage checkpoint,83,reactome
R-HSA-8953750,Transcriptional Regulation by E2F6,34,reactome
R-HSA-9701192,Defective homologous recombination repair (HRR) due to BRCA1 loss of function,25,reactome
R-HSA-9704331,Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function,25,reactome
R-HSA-9704646,Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function,25,reactome
R-HSA-9709570,Impaired BRCA2 binding to RAD51,35,reactome
R-HSA-9709603,Impaired BRCA2 binding to PALB2,24,reactome
R-HSA-5696395,Formation of Incision Complex in GG-NER,43,reactome
R-HSA-5696400,Dual Incision in GG-NER,41,reactome
R-HSA-6783310,Fanconi Anemia Pathway,38,reactome
R-HSA-1655829,Regulation of cholesterol biosynthesis by SREBP (SREBF),15,reactome
R-HSA-8963889,Assembly of active LPL and LIPC lipase complexes,19,reactome
R-HSA-977225,Amyloid fiber formation,110,reactome
R-HSA-381038,XBP1(S) activates chaperone genes,48,reactome
R-HSA-159418,Recycling of bile acids and salts,18,reactome
R-HSA-193368,Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol,23,reactome
R-HSA-193807,Synthesis of bile acids and bile salts via 27-hydroxycholesterol,14,reactome
R-HSA-383280,Nuclear Receptor transcription pathway,53,reactome
R-HSA-4090294,SUMOylation of intracellular receptors,30,reactome
R-HSA-2046106,alpha-linolenic acid (ALA) metabolism,13,reactome
R-HSA-75876,Synthesis of very long-chain fatty acyl-CoAs,24,reactome
R-HSA-2142691,Synthesis of Leukotrienes (LT) and Eoxins (EX),20,reactome
R-HSA-420029,Tight junction interactions,30,reactome
R-HSA-1834949,Cytosolic sensors of pathogen-associated DNA ,23,reactome
R-HSA-73780,RNA Polymerase III Chain Elongation,18,reactome
R-HSA-76061,RNA Polymerase III Transcription Initiation From Type 1 Promoter,28,reactome
R-HSA-76066,RNA Polymerase III Transcription Initiation From Type 2 Promoter,27,reactome
R-HSA-76071,RNA Polymerase III Transcription Initiation From Type 3 Promoter,28,reactome
R-HSA-2197563,NOTCH2 intracellular domain regulates transcription,12,reactome
R-HSA-9013507,NOTCH3 Activation and Transmission of Signal to the Nucleus,24,reactome
R-HSA-113501,Inhibition of replication initiation of damaged DNA by RB1/E2F1,13,reactome
R-HSA-174411,Polymerase switching on the C-strand of the telomere,26,reactome
R-HSA-174430,Telomere C-strand synthesis initiation,13,reactome
R-HSA-69091,Polymerase switching,14,reactome
R-HSA-69166,Removal of the Flap Intermediate,14,reactome
R-HSA-69183,Processive synthesis on the lagging strand,10,reactome
R-HSA-9710421,Defective pyroptosis,72,reactome
R-HSA-9930044,Nuclear RNA decay,35,reactome
R-HSA-8862803,Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models,22,reactome
R-HSA-9864848,Complex IV assembly,48,reactome
R-HSA-9013409,RHOJ GTPase cycle,55,reactome
R-HSA-9733709,Cardiogenesis,27,reactome
R-HSA-8854691,Interleukin-20 family signaling,26,reactome
R-HSA-936837,Ion transport by P-type ATPases,55,reactome
R-HSA-422085,"Synthesis, secretion, and deacylation of Ghrelin",19,reactome
R-HSA-2122948,Activated NOTCH1 Transmits Signal to the Nucleus,31,reactome
R-HSA-2979096,NOTCH2 Activation and Transmission of Signal to the Nucleus,25,reactome
R-HSA-2173795,Downregulation of SMAD2/3:SMAD4 transcriptional activity,31,reactome
R-HSA-2173796,SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription,36,reactome
R-HSA-5578768,Physiological factors,14,reactome
R-HSA-8940973,RUNX2 regulates osteoblast differentiation,24,reactome
R-HSA-5578775,Ion homeostasis,53,reactome
R-HSA-3000480,Scavenging by Class A Receptors,19,reactome
R-HSA-196791,Vitamin D (calciferol) metabolism,12,reactome
R-HSA-1266695,Interleukin-7 signaling,36,reactome
R-HSA-6807004,Negative regulation of MET activity,21,reactome
R-HSA-8875555,MET activates RAP1 and RAC1,11,reactome
R-HSA-8875656,MET receptor recycling,10,reactome
R-HSA-5689896,Ovarian tumor domain proteases,39,reactome
R-HSA-427413,NoRC negatively regulates rRNA expression,105,reactome
R-HSA-69202,Cyclin E associated events during G1/S transition ,28,reactome
R-HSA-69273,Cyclin A/B1/B2 associated events during G2/M transition,32,reactome
R-HSA-69656,Cyclin A:Cdk2-associated events at S phase entry,30,reactome
R-HSA-73762,RNA Polymerase I Transcription Initiation,47,reactome
R-HSA-73772,RNA Polymerase I Promoter Escape,90,reactome
R-HSA-73863,RNA Polymerase I Transcription Termination,31,reactome
R-HSA-8951936,RUNX3 regulates p14-ARF,10,reactome
R-HSA-2559586,DNA Damage/Telomere Stress Induced Senescence,65,reactome
R-HSA-3270619,IRF3-mediated induction of type I IFN,13,reactome
R-HSA-211958,Miscellaneous substrates,12,reactome
R-HSA-211981,Xenobiotics,22,reactome
R-HSA-9668328,Sealing of the nuclear envelope (NE) by ESCRT-III,32,reactome
R-HSA-1482801,Acyl chain remodelling of PS,22,reactome
R-HSA-70635,Urea cycle,10,reactome
R-HSA-1236394,Signaling by ERBB4,19,reactome
R-HSA-1632852,Macroautophagy,68,reactome
R-HSA-168638,NOD1/2 Signaling Pathway,36,reactome
R-HSA-168927,"TICAM1, RIP1-mediated IKK complex recruitment",19,reactome
R-HSA-5357786,TNFR1-induced proapoptotic signaling,25,reactome
R-HSA-5357956,TNFR1-induced NF-kappa-B signaling pathway,33,reactome
R-HSA-5675482,Regulation of necroptotic cell death,26,reactome
R-HSA-71336,Pentose phosphate pathway,12,reactome
R-HSA-2173788,Downregulation of TGF-beta receptor signaling,26,reactome
R-HSA-189483,Heme degradation,15,reactome
R-HSA-9749641,Aspirin ADME,44,reactome
R-HSA-9753281,Paracetamol ADME,29,reactome
R-HSA-165159,MTOR signalling,17,reactome
R-HSA-166208,mTORC1-mediated signalling,24,reactome
R-HSA-380972,Energy dependent regulation of mTOR by LKB1-AMPK,29,reactome
R-HSA-5628897,TP53 Regulates Metabolic Genes,84,reactome
R-HSA-9639288,Amino acids regulate mTORC1,55,reactome
R-HSA-6804757,Regulation of TP53 Degradation,36,reactome
R-HSA-6804759,Regulation of TP53 Activity through Association with Co-factors,14,reactome
R-HSA-69541,Stabilization of p53,11,reactome
R-HSA-2453902,The canonical retinoid cycle in rods (twilight vision),22,reactome
R-HSA-2299718,Condensation of Prophase Chromosomes,73,reactome
R-HSA-68616,Assembly of the ORC complex at the origin of replication,68,reactome
R-HSA-264870,Caspase-mediated cleavage of cytoskeletal proteins,12,reactome
R-HSA-390522,Striated Muscle Contraction,36,reactome
R-HSA-9013422,RHOBTB1 GTPase cycle,23,reactome
R-HSA-140534,Caspase activation via Death Receptors in the presence of ligand,15,reactome
R-HSA-6803211,TP53 Regulates Transcription of Death Receptors and Ligands,12,reactome
R-HSA-2160916,Hyaluronan uptake and degradation,12,reactome
R-HSA-877300,Interferon gamma signaling,90,reactome
R-HSA-1296072,Voltage gated Potassium channels,43,reactome
R-HSA-1483166,Synthesis of PA,39,reactome
R-HSA-8851680,Butyrophilin (BTN) family interactions,12,reactome
R-HSA-114508,Effects of PIP2 hydrolysis,22,reactome
R-HSA-418597,G alpha (z) signalling events,48,reactome
R-HSA-877312,Regulation of IFNG signaling,14,reactome
R-HSA-2995383,Initiation of Nuclear Envelope (NE) Reformation,19,reactome
R-HSA-9013405,RHOD GTPase cycle,53,reactome
R-HSA-9013408,RHOG GTPase cycle,74,reactome
R-HSA-5669034,TNFs bind their physiological receptors,29,reactome
R-HSA-6783783,Interleukin-10 signaling,45,reactome
R-HSA-9933947,Formation of the non-canonical BAF (ncBAF) complex,17,reactome
R-HSA-1169408,ISG15 antiviral mechanism,74,reactome
R-HSA-159227,Transport of the SLBP independent Mature mRNA,35,reactome
R-HSA-159230,Transport of the SLBP Dependant Mature mRNA,36,reactome
R-HSA-159231,Transport of Mature mRNA Derived from an Intronless Transcript,42,reactome
R-HSA-159236,Transport of Mature mRNA derived from an Intron-Containing Transcript,75,reactome
R-HSA-165054,Rev-mediated nuclear export of HIV RNA,35,reactome
R-HSA-168271,Transport of Ribonucleoproteins into the Host Nucleus,32,reactome
R-HSA-168276,NS1 Mediated Effects on Host Pathways,38,reactome
R-HSA-168333,NEP/NS2 Interacts with the Cellular Export Machinery,32,reactome
R-HSA-170822,Regulation of Glucokinase by Glucokinase Regulatory Protein,32,reactome
R-HSA-180746,Nuclear import of Rev protein,34,reactome
R-HSA-180910,Vpr-mediated nuclear import of PICs,34,reactome
R-HSA-191859,snRNP Assembly,53,reactome
R-HSA-3232142,SUMOylation of ubiquitinylation proteins,39,reactome
R-HSA-3301854,Nuclear Pore Complex (NPC) Disassembly,36,reactome
R-HSA-4085377,SUMOylation of SUMOylation proteins,35,reactome
R-HSA-4615885,SUMOylation of DNA replication proteins,46,reactome
R-HSA-5619107,Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC),32,reactome
R-HSA-9609690,HCMV Early Events,138,reactome
R-HSA-9610379,HCMV Late Events,116,reactome
R-HSA-9615933,Postmitotic nuclear pore complex (NPC) reformation,27,reactome
R-HSA-5620971,Pyroptosis,27,reactome
R-HSA-9013420,RHOU GTPase cycle,40,reactome
R-HSA-606279,Deposition of new CENPA-containing nucleosomes at the centromere,72,reactome
R-HSA-379716,Cytosolic tRNA aminoacylation,24,reactome
R-HSA-5620924,Intraflagellar transport,54,reactome
R-HSA-446193,"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein",15,reactome
R-HSA-9843970,Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex,70,reactome
R-HSA-438066,"Unblocking of NMDA receptors, glutamate binding and activation",21,reactome
R-HSA-442982,Ras activation upon Ca2+ influx through NMDA receptor,20,reactome
R-HSA-9609736,Assembly and cell surface presentation of NMDA receptors,44,reactome
R-HSA-9617324,Negative regulation of NMDA receptor-mediated neuronal transmission,21,reactome
R-HSA-9620244,Long-term potentiation,23,reactome
R-HSA-975578,Reactions specific to the complex N-glycan synthesis pathway,10,reactome
R-HSA-8866652,Synthesis of active ubiquitin: roles of E1 and E2 enzymes,30,reactome
R-HSA-109704,PI3K Cascade,39,reactome
R-HSA-1839117,Signaling by cytosolic FGFR1 fusion mutants,18,reactome
R-HSA-8853659,RET signaling,40,reactome
R-HSA-8983432,Interleukin-15 signaling,14,reactome
R-HSA-912526,Interleukin receptor SHC signaling,27,reactome
R-HSA-9607240,FLT3 Signaling,19,reactome
R-HSA-9674555,Signaling by CSF3 (G-CSF),19,reactome
R-HSA-9702518,STAT5 activation downstream of FLT3 ITD mutants,10,reactome
R-HSA-9703465,Signaling by FLT3 fusion proteins,19,reactome
R-HSA-9703648,Signaling by FLT3 ITD and TKD mutants,10,reactome
R-HSA-77387,Insulin receptor recycling,30,reactome
R-HSA-983712,Ion channel transport,24,reactome
R-HSA-9857377,Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy,17,reactome
R-HSA-9013407,RHOH GTPase cycle,37,reactome
R-HSA-450302,activated TAK1 mediates p38 MAPK activation,23,reactome
R-HSA-5210891,Uptake and function of anthrax toxins,11,reactome
R-HSA-1369062,ABC transporters in lipid homeostasis,18,reactome
R-HSA-9603798,Class I peroxisomal membrane protein import,20,reactome
R-HSA-9725370,Signaling by ALK fusions and activated point mutants,60,reactome
R-HSA-9860927,"Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells",31,reactome
R-HSA-9013424,RHOV GTPase cycle,37,reactome
R-HSA-9696273,RND1 GTPase cycle,42,reactome
R-HSA-418889,Caspase activation via Dependence Receptors in the absence of ligand,10,reactome
R-HSA-73817,Purine ribonucleoside monophosphate biosynthesis,11,reactome
R-HSA-9839383,TGFBR3 PTM regulation,11,reactome
R-HSA-110314,Recognition of DNA damage by PCNA-containing replication complex,30,reactome
R-HSA-5651801,PCNA-Dependent Long Patch Base Excision Repair,21,reactome
R-HSA-5656169,Termination of translesion DNA synthesis,32,reactome
R-HSA-9706019,RHOBTB3 ATPase cycle,10,reactome
R-HSA-193775,Synthesis of bile acids and bile salts via 24-hydroxycholesterol,13,reactome
R-HSA-420499,Class C/3 (Metabotropic glutamate/pheromone receptors),39,reactome
R-HSA-6782315,tRNA modification in the nucleus and cytosol,38,reactome
R-HSA-2129379,Molecules associated with elastic fibres,37,reactome
R-HSA-9762293,Regulation of CDH11 gene transcription,10,reactome
R-HSA-156581,Methylation,14,reactome
R-HSA-1650814,Collagen biosynthesis and modifying enzymes,67,reactome
R-HSA-2214320,Anchoring fibril formation,15,reactome
R-HSA-2243919,Crosslinking of collagen fibrils,18,reactome
R-HSA-430039,mRNA decay by 5' to 3' exoribonuclease,15,reactome
R-HSA-351906,Apoptotic cleavage of cell adhesion  proteins,11,reactome
R-HSA-418990,Adherens junctions interactions,32,reactome
R-HSA-5626467,RHO GTPases activate IQGAPs,32,reactome
R-HSA-9823730,Formation of definitive endoderm,15,reactome
R-HSA-9926550,"Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition",12,reactome
R-HSA-201451,Signaling by BMP,31,reactome
R-HSA-8873719,RAB geranylgeranylation,65,reactome
R-HSA-3000170,Syndecan interactions,27,reactome
R-HSA-975634,Retinoid metabolism and transport,44,reactome
R-HSA-2871796,FCERI mediated MAPK activation,32,reactome
R-HSA-5218920,VEGFR2 mediated vascular permeability,27,reactome
R-HSA-70221,Glycogen breakdown (glycogenolysis),15,reactome
R-HSA-983170,"Antigen Presentation: Folding, assembly and peptide loading of class I MHC",29,reactome
R-HSA-9909505,Modulation of host responses by IFN-stimulated genes,19,reactome
R-HSA-917937,Iron uptake and transport,28,reactome
R-HSA-375276,Peptide ligand-binding receptors,106,reactome
R-HSA-381753,Olfactory Signaling Pathway,75,reactome
R-HSA-9733458,Induction of Cell-Cell Fusion,13,reactome
R-HSA-5368286,Mitochondrial translation initiation,88,reactome
R-HSA-5389840,Mitochondrial translation elongation,88,reactome
R-HSA-5419276,Mitochondrial translation termination,88,reactome
R-HSA-2514859,"Inactivation, recovery and regulation of the phototransduction cascade",33,reactome
R-HSA-1442490,Collagen degradation,64,reactome
R-HSA-186797,Signaling by PDGF,33,reactome
R-HSA-2022090,Assembly of collagen fibrils and other multimeric structures,51,reactome
R-HSA-8948216,Collagen chain trimerization,44,reactome
R-HSA-2173789,TGF-beta receptor signaling activates SMADs,27,reactome
R-HSA-1566948,Elastic fibre formation,18,reactome
R-HSA-3214858,RMTs methylate histone arginines,78,reactome
R-HSA-8877330,RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs),10,reactome
R-HSA-2022857,Keratan sulfate degradation,15,reactome
R-HSA-3000171,Non-integrin membrane-ECM interactions,40,reactome
R-HSA-9913351,Formation of the dystrophin-glycoprotein complex (DGC),36,reactome
R-HSA-450321,JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1,22,reactome
R-HSA-450341,Activation of the AP-1 family of transcription factors,10,reactome
R-HSA-186763,Downstream signal transduction,29,reactome
R-HSA-8849471,"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases",14,reactome
R-HSA-201556,Signaling by ALK,19,reactome
R-HSA-2029485,Role of phospholipids in phagocytosis,25,reactome
R-HSA-210993,Tie2 Signaling,18,reactome
R-HSA-512988,"Interleukin-3, Interleukin-5 and GM-CSF signaling",24,reactome
R-HSA-9027276,Erythropoietin activates Phosphoinositide-3-kinase (PI3K),12,reactome
R-HSA-9673767,"Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants",12,reactome
R-HSA-9673770,Signaling by PDGFRA extracellular domain mutants,12,reactome
R-HSA-9842663,Signaling by LTK,12,reactome
R-HSA-9927354,Co-stimulation by ICOS,11,reactome
R-HSA-3299685,Detoxification of Reactive Oxygen Species,37,reactome
R-HSA-72187,mRNA 3'-end processing,58,reactome
R-HSA-73856,RNA Polymerase II Transcription Termination,67,reactome
R-HSA-9692916,SARS-CoV-1 activates/modulates innate immune responses,41,reactome
R-HSA-446107,Type I hemidesmosome assembly,11,reactome
R-HSA-983189,Kinesins,61,reactome
R-HSA-1170546,Prolactin receptor signaling,15,reactome
R-HSA-5684264,MAP3K8 (TPL2)-dependent MAPK1/3 activation,16,reactome
R-HSA-9708530,Regulation of BACH1 activity,11,reactome
R-HSA-9725371,Nuclear events stimulated by ALK signaling in cancer,34,reactome
R-HSA-1251985,Nuclear signaling by ERBB4,32,reactome
R-HSA-445989,TAK1-dependent IKK and NF-kappa-B activation  ,35,reactome
R-HSA-9014325,"TICAM1,TRAF6-dependent induction of TAK1 complex",11,reactome
R-HSA-937042,IRAK2 mediated activation of TAK1 complex,10,reactome
R-HSA-9645460,Alpha-protein kinase 1 signaling pathway,11,reactome
R-HSA-975163,IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation,15,reactome
R-HSA-4755510,SUMOylation of immune response proteins,12,reactome
R-HSA-909733,Interferon alpha/beta signaling,75,reactome
R-HSA-9833482,PKR-mediated signaling,76,reactome
R-HSA-3214841,PKMTs methylate histone lysines,70,reactome
R-HSA-9818564,Epigenetic regulation of gene expression by MLL3 and MLL4 complexes,10,reactome
R-HSA-3295583,TRP channels,28,reactome
R-HSA-3322077,Glycogen synthesis,14,reactome
R-HSA-159740,Gamma-carboxylation of protein precursors,10,reactome
R-HSA-159782,Removal of aminoterminal propeptides from gamma-carboxylated proteins,10,reactome
R-HSA-9701898,STAT3 nuclear events downstream of ALK signaling,11,reactome
R-HSA-9827857,Specification of primordial germ cells,12,reactome
R-HSA-5205685,PINK1-PRKN Mediated Mitophagy,32,reactome
R-HSA-8934903,Receptor Mediated Mitophagy,11,reactome
R-HSA-427389,ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression,75,reactome
R-HSA-9843940,Regulation of endogenous retroelements by KRAB-ZFP proteins,107,reactome
R-HSA-9844594,Transcriptional regulation of brown and beige adipocyte differentiation by EBF2,31,reactome
R-HSA-5625740,RHO GTPases activate PKNs,28,reactome
R-HSA-5625900,RHO GTPases activate CIT,19,reactome
R-HSA-5627117,RHO GTPases Activate ROCKs,19,reactome
R-HSA-5627123,RHO GTPases activate PAKs,21,reactome
R-HSA-5673000,RAF activation,34,reactome
R-HSA-9022692,Regulation of MECP2 expression and activity,31,reactome
R-HSA-418359,Reduction of cytosolic Ca++ levels,12,reactome
R-HSA-211979,Eicosanoids,12,reactome
R-HSA-2162123,Synthesis of Prostaglandins (PG) and Thromboxanes (TX),15,reactome
R-HSA-8964539,Glutamate and glutamine metabolism,14,reactome
R-HSA-189200,Cellular hexose transport,21,reactome
R-HSA-9022699,MECP2 regulates neuronal receptors and channels,18,reactome
R-HSA-112043,PLC beta mediated events,12,reactome
R-HSA-202040,G-protein activation,24,reactome
R-HSA-399997,Acetylcholine regulates insulin secretion,10,reactome
R-HSA-418592,ADP signalling through P2Y purinoceptor 1,25,reactome
R-HSA-456926,Thrombin signalling through proteinase activated receptors (PARs),32,reactome
R-HSA-6814122,Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding,38,reactome
R-HSA-70268,Pyruvate metabolism,19,reactome
R-HSA-390247,Beta-oxidation of very long chain fatty acids,11,reactome
R-HSA-70895,Branched-chain amino acid catabolism,21,reactome
R-HSA-75109,Triglyceride biosynthesis,14,reactome
R-HSA-71403,Citric acid cycle (TCA cycle),17,reactome
R-HSA-9854311,Maturation of TCA enzymes and regulation of TCA cycle,20,reactome
R-HSA-2468052,Establishment of Sister Chromatid Cohesion,11,reactome
R-HSA-2470946,Cohesin Loading onto Chromatin,10,reactome
R-HSA-174414,Processive synthesis on the C-strand of the telomere,14,reactome
R-HSA-174417,Telomere C-strand (Lagging Strand) Synthesis,11,reactome
R-HSA-174437,Removal of the Flap Intermediate from the C-strand,17,reactome
R-HSA-5358565,Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha),14,reactome
R-HSA-5358606,Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta),14,reactome
R-HSA-429947,Deadenylation of mRNA,25,reactome
R-HSA-9820841,M-decay: degradation of maternal mRNAs by maternally stored factors,33,reactome
R-HSA-9820865,Z-decay: degradation of maternal mRNAs by zygotically expressed factors,12,reactome
R-HSA-1660661,Sphingolipid de novo biosynthesis,37,reactome
R-HSA-9629569,Protein hydroxylation,20,reactome
R-HSA-182971,EGFR downregulation,31,reactome
R-HSA-3656237,Defective EXT2 causes exostoses 2,14,reactome
R-HSA-3656253,"Defective EXT1 causes exostoses 1, TRPS2 and CHDS",14,reactome
R-HSA-376176,Signaling by ROBO receptors,15,reactome
R-HSA-9694614,Attachment and Entry,19,reactome
R-HSA-9820960,Respiratory syncytial virus (RSV) attachment and entry,23,reactome
R-HSA-111465,Apoptotic cleavage of cellular proteins,18,reactome
R-HSA-9758274,Regulation of NF-kappa B signaling,18,reactome
R-HSA-1912420,Pre-NOTCH Processing in Golgi,18,reactome
R-HSA-9037629,Lewis blood group biosynthesis,16,reactome
R-HSA-193692,Regulated proteolysis of p75NTR,11,reactome
R-HSA-205043,NRIF signals cell death from the nucleus,16,reactome
R-HSA-209543,p75NTR recruits signalling complexes,13,reactome
R-HSA-209560,NF-kB is activated and signals survival,13,reactome
R-HSA-5635838,Activation of SMO,18,reactome
R-HSA-419408,Lysosphingolipid and LPA receptors,14,reactome
R-HSA-110328,Recognition and association of DNA glycosylase with site containing an affected pyrimidine,60,reactome
R-HSA-110329,Cleavage of the damaged pyrimidine ,60,reactome
R-HSA-170670,Adenylate cyclase inhibitory pathway,14,reactome
R-HSA-392170,ADP signalling through P2Y purinoceptor 12,22,reactome
R-HSA-9009391,Extra-nuclear estrogen signaling,56,reactome
R-HSA-373752,Netrin-1 signaling,19,reactome
R-HSA-418890,Role of second messengers in netrin-1 signaling,10,reactome
R-HSA-428542,Regulation of commissural axon pathfinding by SLIT and ROBO,10,reactome
R-HSA-1250196,SHC1 events in ERBB2 signaling,22,reactome
R-HSA-1358803,Downregulation of ERBB2:ERBB3 signaling,13,reactome
R-HSA-1963642,PI3K events in ERBB2 signaling,16,reactome
R-HSA-6785631,ERBB2 Regulates Cell Motility,15,reactome
R-HSA-8847993,ERBB2 Activates PTK6 Signaling,13,reactome
R-HSA-9664565,Signaling by ERBB2 KD Mutants,25,reactome
R-HSA-9665686,Signaling by ERBB2 TMD/JMD mutants,22,reactome
R-HSA-2408522,Selenoamino acid metabolism,11,reactome
R-HSA-9648002,RAS processing,24,reactome
R-HSA-3769402,Deactivation of the beta-catenin transactivating complex,42,reactome
R-HSA-4641265,Repression of WNT target genes,14,reactome
R-HSA-196757,Metabolism of folate and pterines,17,reactome
R-HSA-196299,Beta-catenin phosphorylation cascade,17,reactome
R-HSA-5339716,Signaling by GSK3beta mutants,15,reactome
R-HSA-5358747,CTNNB1 S33 mutants aren't phosphorylated,15,reactome
R-HSA-5358749,CTNNB1 S37 mutants aren't phosphorylated,15,reactome
R-HSA-5358751,CTNNB1 S45 mutants aren't phosphorylated,15,reactome
R-HSA-5358752,CTNNB1 T41 mutants aren't phosphorylated,15,reactome
R-HSA-5467337,APC truncation mutants have impaired AXIN binding,14,reactome
R-HSA-5467340,AXIN missense mutants destabilize the destruction complex,14,reactome
R-HSA-5467348,Truncations of AMER1 destabilize the destruction complex,14,reactome
R-HSA-9933939,Formation of the polybromo-BAF (pBAF) complex,18,reactome
R-HSA-9933946,Formation of the embryonic stem cell BAF (esBAF) complex,19,reactome
R-HSA-9616222,Transcriptional regulation of granulopoiesis,89,reactome
R-HSA-5689877,Josephin domain DUBs,12,reactome
R-HSA-9615017,"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes",30,reactome
R-HSA-190375,FGFR2c ligand binding and activation,13,reactome
R-HSA-190377,FGFR2b ligand binding and activation,10,reactome
R-HSA-2033519,Activated point mutants of FGFR2,17,reactome
R-HSA-5654221,Phospholipase C-mediated cascade; FGFR2,18,reactome
R-HSA-5654695,PI-3K cascade:FGFR2,23,reactome
R-HSA-5654699,SHC-mediated cascade:FGFR2,23,reactome
R-HSA-5654700,FRS-mediated FGFR2 signaling,25,reactome
R-HSA-5654727,Negative regulation of FGFR2 signaling,27,reactome
R-HSA-5655253,Signaling by FGFR2 in disease,27,reactome
R-HSA-70171,Glycolysis,30,reactome
R-HSA-9856532,Mechanical load activates signaling by PIEZO1 and integrins in osteocytes,17,reactome
R-HSA-8876725,Protein methylation,17,reactome
R-HSA-2173791,TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition),16,reactome
R-HSA-392451,G beta:gamma signalling through PI3Kgamma,25,reactome
R-HSA-416572,Sema4D induced cell migration and growth-cone collapse,20,reactome
R-HSA-5625970,RHO GTPases activate KTN1,11,reactome
R-HSA-5218921,VEGFR2 mediated cell proliferation,19,reactome
R-HSA-888590,"GABA synthesis, release, reuptake and degradation",13,reactome
R-HSA-8878166,Transcriptional regulation by RUNX2,15,reactome
R-HSA-8934593,Regulation of RUNX1 Expression and Activity,17,reactome
R-HSA-1839130,Signaling by activated point mutants of FGFR3,12,reactome
R-HSA-190372,FGFR3c ligand binding and activation,13,reactome
R-HSA-5654227,Phospholipase C-mediated cascade; FGFR3,13,reactome
R-HSA-5654704,SHC-mediated cascade:FGFR3,18,reactome
R-HSA-5654706,FRS-mediated FGFR3 signaling,20,reactome
R-HSA-5654710,PI-3K cascade:FGFR3,18,reactome
R-HSA-5654732,Negative regulation of FGFR3 signaling,22,reactome
R-HSA-5655332,Signaling by FGFR3 in disease,22,reactome
R-HSA-198753,ERK/MAPK targets,17,reactome
R-HSA-9752946,Expression and translocation of olfactory receptors,395,reactome
R-HSA-392517,Rap1 signalling,16,reactome
R-HSA-139853,Elevation of cytosolic Ca2+ levels,15,reactome
R-HSA-5683826,Surfactant metabolism,29,reactome
R-HSA-1502540,Signaling by Activin,15,reactome
R-HSA-9839394,TGFBR3 expression,25,reactome
R-HSA-1482788,Acyl chain remodelling of PC,27,reactome
R-HSA-1482839,Acyl chain remodelling of PE,29,reactome
R-HSA-1482922,Acyl chain remodelling of PI,17,reactome
R-HSA-1482925,Acyl chain remodelling of PG,18,reactome
R-HSA-1296041,Activation of G protein gated Potassium channels,29,reactome
R-HSA-392851,Prostacyclin signalling through prostacyclin receptor,19,reactome
R-HSA-4086398,Ca2+ pathway,62,reactome
R-HSA-418217,G beta:gamma signalling through PLC beta,20,reactome
R-HSA-500657,Presynaptic function of Kainate receptors,21,reactome
R-HSA-8964616,G beta:gamma signalling through CDC42,20,reactome
R-HSA-997272,Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits,29,reactome
R-HSA-264876,Insulin processing,25,reactome
R-HSA-3772470,Negative regulation of TCF-dependent signaling by WNT ligand antagonists,15,reactome
R-HSA-4641263,Regulation of FZD by ubiquitination,21,reactome
R-HSA-5654219,Phospholipase C-mediated cascade: FGFR1,16,reactome
R-HSA-5654687,Downstream signaling of activated FGFR1,18,reactome
R-HSA-5654688,SHC-mediated cascade:FGFR1,21,reactome
R-HSA-5654689,PI-3K cascade:FGFR1,21,reactome
R-HSA-5654693,FRS-mediated FGFR1 signaling,23,reactome
R-HSA-5658623,FGFRL1 modulation of FGFR1 signaling,13,reactome
R-HSA-9937080,Developmental Lineage of Multipotent Pancreatic Progenitor Cells,18,reactome
R-HSA-1483191,Synthesis of PC,28,reactome
R-HSA-425366,"Transport of bile salts and organic acids, metal ions and amine compounds",11,reactome
R-HSA-190873,Gap junction degradation,12,reactome
R-HSA-196025,Formation of annular gap junctions,11,reactome
R-HSA-9648895,Response of EIF2AK1 (HRI) to heme deficiency,15,reactome
R-HSA-2485179,Activation of the phototransduction cascade,11,reactome
R-HSA-9828806,Maturation of hRSV A proteins,14,reactome
R-HSA-9717207,"Sensory perception of sweet, bitter, and umami (glutamate) taste",41,reactome
R-HSA-428540,Activation of RAC1,13,reactome
R-HSA-975577,N-Glycan antennae elongation,15,reactome
R-HSA-8955332,Carboxyterminal post-translational modifications of tubulin,46,reactome
R-HSA-901032,ER Quality Control Compartment (ERQC),21,reactome
R-HSA-6804758,Regulation of TP53 Activity through Acetylation,23,reactome
R-HSA-77595,Processing of Intronless Pre-mRNAs,20,reactome
R-HSA-9634600,"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism",12,reactome
R-HSA-9008059,Interleukin-37 signaling,21,reactome
R-HSA-446353,Cell-extracellular matrix interactions,12,reactome
R-HSA-9609523,Insertion of tail-anchored proteins into the endoplasmic reticulum membrane,22,reactome
R-HSA-9705462,Inactivation of CSF3 (G-CSF) signaling,25,reactome
R-HSA-5607763,CLEC7A (Dectin-1) induces NFAT activation,11,reactome
R-HSA-418457,cGMP effects,16,reactome
R-HSA-164940,Nef mediated downregulation of MHC class I complex cell surface expression,10,reactome
R-HSA-176974,Unwinding of DNA,12,reactome
R-HSA-6803205,TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain,14,reactome
R-HSA-9821002,Chromatin modifications during the maternal to zygotic transition (MZT),70,reactome
R-HSA-9796292,Formation of axial mesoderm,14,reactome
R-HSA-174490,Membrane binding and targetting of GAG proteins,14,reactome
R-HSA-1475029,Reversible hydration of carbon dioxide,12,reactome
R-HSA-425561,Sodium/Calcium exchangers,11,reactome
R-HSA-5694530,Cargo concentration in the ER,33,reactome
R-HSA-70263,Gluconeogenesis,26,reactome
R-HSA-1839122,Signaling by activated point mutants of FGFR1,11,reactome
R-HSA-190322,FGFR4 ligand binding and activation,13,reactome
R-HSA-5654228,Phospholipase C-mediated cascade; FGFR4,15,reactome
R-HSA-5654712,FRS-mediated FGFR4 signaling,22,reactome
R-HSA-5654719,SHC-mediated cascade:FGFR4,20,reactome
R-HSA-5654720,PI-3K cascade:FGFR4,20,reactome
R-HSA-5654733,Negative regulation of FGFR4 signaling,24,reactome
R-HSA-5655302,Signaling by FGFR1 in disease,33,reactome
R-HSA-389957,Prefoldin mediated transfer of substrate  to CCT/TriC,28,reactome
R-HSA-390450,Folding of actin by CCT/TriC,10,reactome
R-HSA-5696394,DNA Damage Recognition in GG-NER,38,reactome
R-HSA-451308,Activation of Ca-permeable Kainate Receptor,10,reactome
R-HSA-8849932,Synaptic adhesion-like molecules,21,reactome
R-HSA-190840,Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane,20,reactome
R-HSA-190861,Gap junction assembly,38,reactome
R-HSA-389960,Formation of tubulin folding intermediates by CCT/TriC,26,reactome
R-HSA-389977,Post-chaperonin tubulin folding pathway,23,reactome
R-HSA-5617833,Cilium Assembly,20,reactome
R-HSA-9619483,Activation of AMPK downstream of NMDARs,29,reactome
R-HSA-9830364,Formation of the nephric duct,18,reactome
R-HSA-9831926,Nephron development,13,reactome
R-HSA-429958,mRNA decay by 3' to 5' exoribonuclease,16,reactome
R-HSA-450385,Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA,17,reactome
R-HSA-450513,"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA",17,reactome
R-HSA-450604,KSRP (KHSRP) binds and destabilizes mRNA,17,reactome
R-HSA-196780,Biotin transport and metabolism,11,reactome
R-HSA-200425,Carnitine shuttle,14,reactome
R-HSA-180292,GAB1 signalosome,17,reactome
R-HSA-74259,Purine catabolism,10,reactome
R-HSA-9755088,Ribavirin ADME,11,reactome
R-HSA-1810476,RIP-mediated NFkB activation via ZBP1,17,reactome
R-HSA-844456,The NLRP3 inflammasome,16,reactome
R-HSA-933542,TRAF6 mediated NF-kB activation,25,reactome
R-HSA-9660826,Purinergic signaling in leishmaniasis infection,26,reactome
R-HSA-9679504,Translation of Replicase and Assembly of the Replication Transcription Complex,13,reactome
R-HSA-9694676,Translation of Replicase and Assembly of the Replication Transcription Complex,13,reactome
R-HSA-163359,Glucagon signaling in metabolic regulation,26,reactome
R-HSA-170660,Adenylate cyclase activating pathway,10,reactome
R-HSA-417957,P2Y receptors,12,reactome
R-HSA-8986944,Transcriptional Regulation by MECP2,17,reactome
R-HSA-9824594,Regulation of MITF-M-dependent genes involved in apoptosis,18,reactome
R-HSA-1295596,Spry regulation of FGF signaling,16,reactome
R-HSA-166016,Toll Like Receptor 4 (TLR4) Cascade,18,reactome
R-HSA-9031628,NGF-stimulated transcription,39,reactome
R-HSA-1474244,Extracellular matrix organization,15,reactome
R-HSA-2022377,Metabolism of Angiotensinogen to Angiotensins,17,reactome
R-HSA-629594,Highly calcium permeable postsynaptic nicotinic acetylcholine receptors,11,reactome
R-HSA-6804115,TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain,21,reactome
R-HSA-9013700,NOTCH4 Activation and Transmission of Signal to the Nucleus,11,reactome
R-HSA-1236382,Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants,19,reactome
R-HSA-1474151,"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation",10,reactome
R-HSA-168928,DDX58/IFIH1-mediated induction of interferon-alpha/beta,23,reactome
R-HSA-203615,eNOS activation,13,reactome
R-HSA-5637810,Constitutive Signaling by EGFRvIII,15,reactome
R-HSA-9634285,Constitutive Signaling by Overexpressed ERBB2,11,reactome
R-HSA-9665348,Signaling by ERBB2 ECD mutants,16,reactome
R-HSA-1362277,Transcription of E2F targets under negative control by DREAM complex,19,reactome
R-HSA-1362300,Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1,16,reactome
R-HSA-1538133,G0 and Early G1,18,reactome
R-HSA-6804114,TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest,18,reactome
R-HSA-69205,G1/S-Specific Transcription,29,reactome
R-HSA-9754189,Germ layer formation at gastrulation,17,reactome
R-HSA-9825892,Regulation of MITF-M-dependent genes involved in cell cycle and proliferation,18,reactome
R-HSA-8984722,Interleukin-35 Signalling,12,reactome
R-HSA-9020591,Interleukin-12 signaling,10,reactome
R-HSA-5576886,Phase 4 - resting membrane potential,19,reactome
R-HSA-9683610,Maturation of nucleoprotein,11,reactome
R-HSA-9694631,Maturation of nucleoprotein,15,reactome
R-HSA-9634638,Estrogen-dependent nuclear events downstream of ESR-membrane signaling,24,reactome
R-HSA-2142789,Ubiquinol biosynthesis,13,reactome
R-HSA-879518,Transport of organic anions,11,reactome
R-HSA-5686938,Regulation of TLR by endogenous ligand,22,reactome
R-HSA-8963888,Chylomicron assembly,10,reactome
R-HSA-8963901,Chylomicron remodeling,10,reactome
R-HSA-2534343,Interaction With Cumulus Cells And The Zona Pellucida,11,reactome
R-HSA-9757110,Prednisone ADME,10,reactome
R-HSA-8875360,InlB-mediated entry of Listeria monocytogenes into host cell,15,reactome
R-HSA-9841251,Mitochondrial unfolded protein response (UPRmt),18,reactome
R-HSA-432047,Passive transport by Aquaporins,13,reactome
R-HSA-1855204,Synthesis of IP3 and IP4 in the cytosol,26,reactome
R-HSA-8964058,HDL remodeling,10,reactome
R-HSA-5661231,Metallothioneins bind metals,11,reactome
R-HSA-156584,Cytosolic sulfonation of small molecules,18,reactome
R-HSA-5334118,DNA methylation,64,reactome
R-HSA-1461957,Beta defensins,39,reactome
R-HSA-1461973,Defensins,40,reactome
R-HSA-140837,Intrinsic Pathway of Fibrin Clot Formation,23,reactome
R-HSA-532668,N-glycan trimming in the ER and Calnexin/Calreticulin cycle,16,reactome
R-HSA-6804116,TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest,14,reactome
R-HSA-9617828,FOXO-mediated transcription of cell cycle genes,17,reactome
R-HSA-76009,Platelet Aggregation (Plug Formation),10,reactome
R-HSA-9706369,Negative regulation of FLT3,15,reactome
R-HSA-428643,Organic anion transporters,12,reactome
R-HSA-9925561,Developmental Lineage of Pancreatic Acinar Cells,32,reactome
R-HSA-110330,Recognition and association of DNA glycosylase with site containing an affected purine,55,reactome
R-HSA-110331,Cleavage of the damaged purine,55,reactome
R-HSA-171306,Packaging Of Telomere Ends,51,reactome
R-HSA-171319,Telomere Extension By Telomerase,23,reactome
R-HSA-977347,Serine metabolism,11,reactome
R-HSA-9821993,Replacement of protamines by nucleosomes in the male pronucleus,42,reactome
R-HSA-427359,SIRT1 negatively regulates rRNA expression,67,reactome
R-HSA-1059683,Interleukin-6 signaling,11,reactome
R-HSA-110056,MAPK3 (ERK1) activation,10,reactome
R-HSA-2586552,Signaling by Leptin,11,reactome
R-HSA-9027284,Erythropoietin activates RAS,14,reactome
R-HSA-982772,Growth hormone receptor signaling,24,reactome
R-HSA-75105,Fatty acyl-CoA biosynthesis,13,reactome
R-HSA-163210,Formation of ATP by chemiosmotic coupling,20,reactome
R-HSA-140875,Common Pathway of Fibrin Clot Formation,22,reactome
R-HSA-170968,Frs2-mediated activation,12,reactome
R-HSA-2559584,Formation of Senescence-Associated Heterochromatin Foci (SAHF),17,reactome
R-HSA-111367,SLBP independent Processing of Histone Pre-mRNAs,10,reactome
R-HSA-77588,SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,11,reactome
R-HSA-112409,RAF-independent MAPK1/3 activation,13,reactome
R-HSA-1181150,Signaling by NODAL,23,reactome
R-HSA-162658,Golgi Cisternae Pericentriolar Stack Reorganization,14,reactome
R-HSA-202670,ERKs are inactivated,13,reactome
R-HSA-74749,Signal attenuation,10,reactome
R-HSA-879415,Advanced glycosylation endproduct receptor signaling,13,reactome
R-HSA-9627069,Regulation of the apoptosome activity,11,reactome
R-HSA-211935,Fatty acids,15,reactome
R-HSA-211999,CYP2E1 reactions,11,reactome
R-HSA-1362409,Mitochondrial iron-sulfur cluster biogenesis,12,reactome
R-HSA-1483213,Synthesis of PE,13,reactome
R-HSA-2168880,Scavenging of heme from plasma,13,reactome
R-HSA-9020558,Interleukin-2 signaling,12,reactome
R-HSA-156711,Polo-like kinase mediated events,16,reactome
R-HSA-6804760,Regulation of TP53 Activity through Methylation,19,reactome
R-HSA-9735871,SARS-CoV-1 targets host intracellular signalling and regulatory pathways,16,reactome
R-HSA-9840309,Glycosphingolipid biosynthesis,19,reactome
R-HSA-1679131,Trafficking and processing of endosomal TLR,13,reactome
R-HSA-1855167,Synthesis of pyrophosphates in the cytosol,10,reactome
R-HSA-913709,O-linked glycosylation of mucins,54,reactome
R-HSA-74217,Purine salvage,13,reactome
R-HSA-2892247,"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation",13,reactome
R-HSA-452723,Transcriptional regulation of pluripotent stem cells,17,reactome
R-HSA-389661,Glyoxylate metabolism and glycine degradation,12,reactome
R-HSA-2691232,Constitutive Signaling by NOTCH1 HD Domain Mutants,15,reactome
R-HSA-177929,Signaling by EGFR,17,reactome
R-HSA-4419969,Depolymerization of the Nuclear Lamina,15,reactome
R-HSA-112314,Neurotransmitter receptors and postsynaptic signal transmission,10,reactome
R-HSA-446203,Asparagine N-linked glycosylation,15,reactome
R-HSA-390666,Serotonin receptors,12,reactome
R-HSA-9690406,Transcriptional regulation of testis differentiation,13,reactome
R-HSA-197264,Nicotinamide salvage,16,reactome
R-HSA-2892245,"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation",10,reactome
R-HSA-73728,RNA Polymerase I Promoter Opening,62,reactome
R-HSA-71240,Tryptophan catabolism,14,reactome
R-HSA-9020958,Interleukin-21 signaling,10,reactome
R-HSA-937039,IRAK1 recruits IKK complex,14,reactome
R-HSA-975144,IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation,14,reactome
R-HSA-442380,Zinc influx into cells by the SLC39 gene family,10,reactome
R-HSA-2465910,MASTL Facilitates Mitotic Progression,10,reactome
R-HSA-193048,Androgen biosynthesis,11,reactome
R-HSA-209822,Glycoprotein hormones,12,reactome
R-HSA-375281,Hormone ligand-binding receptors,12,reactome
R-HSA-198693,AKT phosphorylates targets in the nucleus,10,reactome
R-HSA-9614399,Regulation of localization of FOXO transcription factors,12,reactome
R-HSA-9755779,SARS-CoV-2 targets host intracellular signalling and regulatory pathways,12,reactome
R-HSA-912694,Regulation of IFNA/IFNB signaling,26,reactome
R-HSA-388844,Receptor-type tyrosine-protein phosphatases,20,reactome
R-HSA-9748787,Azathioprine ADME,23,reactome
R-HSA-5083632,Defective C1GALT1C1 causes TNPS,17,reactome
R-HSA-2151209,Activation of PPARGC1A (PGC-1alpha) by phosphorylation,10,reactome
R-HSA-9832991,Formation of the posterior neural plate,10,reactome
R-HSA-140342,Apoptosis induced DNA fragmentation,13,reactome
R-HSA-430116,GP1b-IX-V activation signalling,12,reactome
R-HSA-9700645,ALK mutants bind TKIs,12,reactome
R-HSA-75035,Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex,15,reactome
R-HSA-156588,Glucuronidation,22,reactome
R-HSA-179812,GRB2 events in EGFR signaling,13,reactome
R-HSA-180336,SHC1 events in EGFR signaling,14,reactome
R-HSA-5655291,Signaling by FGFR4 in disease,11,reactome
R-HSA-3134975,Regulation of innate immune responses to cytosolic DNA,14,reactome
R-HSA-71384,Ethanol oxidation,12,reactome
R-HSA-199220,Vitamin B5 (pantothenate) metabolism,13,reactome
R-HSA-1250342,PI3K events in ERBB4 signaling,10,reactome
R-HSA-1250347,SHC1 events in ERBB4 signaling,14,reactome
R-HSA-1963640,GRB2 events in ERBB2 signaling,16,reactome
R-HSA-1236977,Endosomal/Vacuolar pathway,11,reactome
R-HSA-5620922,BBSome-mediated cargo-targeting to cilium,23,reactome
R-HSA-1433617,Regulation of signaling by NODAL,12,reactome
R-HSA-194002,Glucocorticoid biosynthesis,10,reactome
R-HSA-5083625,Defective GALNT3 causes HFTC,16,reactome
R-HSA-167044,Signalling to RAS,10,reactome
R-HSA-9028731,Activated NTRK2 signals through FRS2 and FRS3,11,reactome
R-HSA-9664873,Pexophagy,11,reactome
R-HSA-3247509,Chromatin modifying enzymes,20,reactome
R-HSA-5083636,Defective GALNT12 causes CRCS1,16,reactome
R-HSA-373076,Class A/1 (Rhodopsin-like receptors),19,reactome
R-HSA-9013973,TICAM1-dependent activation of IRF3/IRF7,13,reactome
R-HSA-9824878,"Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 ",14,reactome
R-HSA-9828211,"Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation",11,reactome
R-HSA-975110,TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling,13,reactome