# Evaluation metrics for medical image segmentation # Dice coefficient and IoU (Intersection over Union) import torch import torch.nn.functional as F import numpy as np def compute_dice_iou_binary(pred_logits, targets, threshold=0.5): """Compute per-sample Dice and IoU for binary segmentation, then average. Args: pred_logits: [B, 1, H, W] logits (before sigmoid) targets: [B, 1, H, W] binary mask {0, 1} Returns: dice: scalar, mean per-sample foreground Dice iou: scalar, mean per-sample foreground IoU """ B = pred_logits.size(0) probs = torch.sigmoid(pred_logits) preds = (probs > threshold).float() # Per-sample: flatten spatial dims only [B, N] preds_flat = preds.view(B, -1) targets_flat = targets.view(B, -1) intersection = (preds_flat * targets_flat).sum(dim=1) # [B] pred_sum = preds_flat.sum(dim=1) # [B] target_sum = targets_flat.sum(dim=1) # [B] smooth = 1e-6 dice_per_sample = (2.0 * intersection + smooth) / (pred_sum + target_sum + smooth) # [B] iou_per_sample = (intersection + smooth) / (pred_sum + target_sum - intersection + smooth) # [B] return dice_per_sample.mean().item(), iou_per_sample.mean().item() def compute_dice_iou_multiclass(pred_logits, targets, num_classes=3): """Compute per-sample mean Dice and IoU for multi-class segmentation. For REFUGE2: report mean of optic cup (class 1) and optic disc (class 2). Computes Dice per sample per class, then averages. Args: pred_logits: [B, C, H, W] logits (before softmax) targets: [B, H, W] class indices {0, ..., C-1} Returns: mean_dice: mean per-sample Dice over foreground classes mean_iou: mean per-sample IoU over foreground classes per_class_dice: dict of {class_idx: mean_dice} per_class_iou: dict of {class_idx: mean_iou} """ B = pred_logits.size(0) preds = pred_logits.argmax(dim=1) # [B, H, W] smooth = 1e-6 per_class_dice = {} per_class_iou = {} # Skip background (class 0), compute for foreground classes for c in range(1, num_classes): pred_c = (preds == c).float().view(B, -1) # [B, N] target_c = (targets == c).float().view(B, -1) # [B, N] intersection = (pred_c * target_c).sum(dim=1) # [B] pred_sum = pred_c.sum(dim=1) # [B] target_sum = target_c.sum(dim=1) # [B] dice_per_sample = (2.0 * intersection + smooth) / (pred_sum + target_sum + smooth) iou_per_sample = (intersection + smooth) / (pred_sum + target_sum - intersection + smooth) per_class_dice[c] = dice_per_sample.mean().item() per_class_iou[c] = iou_per_sample.mean().item() mean_dice = np.mean(list(per_class_dice.values())) mean_iou = np.mean(list(per_class_iou.values())) return mean_dice, mean_iou, per_class_dice, per_class_iou class MetricTracker: """Track running averages of metrics during training/evaluation.""" def __init__(self): self.reset() def reset(self): self.dice_sum = 0.0 self.iou_sum = 0.0 self.count = 0 def update(self, dice, iou, batch_size=1): self.dice_sum += dice * batch_size self.iou_sum += iou * batch_size self.count += batch_size @property def avg_dice(self): return self.dice_sum / max(self.count, 1) @property def avg_iou(self): return self.iou_sum / max(self.count, 1)