import numpy as np import cv2 from typing import TypeVar, Optional from PIL import Image import albumentations as A from pathlib import Path import seaborn as sns T = TypeVar("T", bound=np.number) SampleArg = tuple[T, T] | T CATEGORIES: dict[str, int] = { "SA": 1, "LI": 2, "RI": 3, } LABELS: dict[int, str] = {v: k for k, v in CATEGORIES.items()} def sample(x: SampleArg) -> T: return np.random.uniform(x[0], x[1]) if isinstance(x, tuple) else x class Dropout(A.PixelDropout): def apply_to_bbox(self, bbox, **params): return bbox def apply_to_keypoint(self, keypoint, **params): return keypoint def apply_to_mask(self, img: np.ndarray, **params) -> np.ndarray: return img class CoarseDropout(A.CoarseDropout): def apply_to_bbox(self, bbox, **params): return bbox def apply_to_keypoint(self, keypoint, **params): return keypoint def apply_to_mask(self, img: np.ndarray, **params) -> np.ndarray: return img def gaussian_contrast_fn( images: np.ndarray, alpha: float | tuple[float, float] = (0.6, 1.4), sigma: float | tuple[float, float] = (0.1, 0.5), max_value: float = 1, ): original_type = images.dtype images = images.astype(np.float32) / max_value N, H, W, C = images.shape if isinstance(alpha, tuple): alpha = np.random.uniform(alpha[0], alpha[1]) if isinstance(sigma, tuple): s = np.random.uniform(sigma[0], sigma[1]) * min(H, W) else: s = sigma * min(H, W) mu_x = np.random.uniform(0, H, size=N) mu_y = np.random.uniform(0, W, size=N) xs, ys = np.meshgrid( np.arange(H, dtype=np.float32), np.arange(W, dtype=np.float32), indexing="ij" ) xdiff = xs[:, :, None] - mu_x[None, None, :] ydiff = ys[:, :, None] - mu_y[None, None, :] distance_squared = xdiff**2 + ydiff**2 h = np.exp(-distance_squared / (2 * s * s)) hmax = np.max(h, axis=(0, 1), keepdims=True) hmap = h / hmax # in [0, 1] alpha_map = hmap * (alpha - 1) + 1 images = 0.5 + (images - 0.5) * alpha_map images = np.clip(images, 0, 1) images = (images * max_value).astype(original_type) return images def gaussian_contrast_aug( alpha: float | tuple[float, float] = (0.6, 1.4), sigma: float | tuple[float, float] = (0.1, 0.5), max_value: float = 1, ) -> A.Lambda: """Nonuniform contrast augmentation. Adjust the contrast by scaling each pixel with value `v` at `x` to `0.5 + (v - 0.5) * exp(-(x - mu)**2 / (2 * sigma**2)))` Args: alpha (float or tuple of float): Alpha of the nonuniform contrast augmentation. If a tuple is provided, the value will be randomly selected from the range. sigma (float or tuple of float): Standard deviation of the Gaussian kernel, as a fraction of the (smaller) image size. If a tuple is provided, the value will be randomly selected from the range. Returns: imgaug.augmenters.Lambda: The augmenter. """ if isinstance(alpha, tuple): assert len(alpha) == 2 assert alpha[0] <= alpha[1] if isinstance(sigma, tuple): assert len(sigma) == 2 assert sigma[0] <= sigma[1] sigma = np.random.uniform(sigma[0], sigma[1]) def f_image(image, **kwargs): # Images are in NHWC return gaussian_contrast_fn(np.array([image]), alpha, sigma, max_value=max_value)[0] def f_id(x, **kwargs): return x return A.Lambda( image=f_image, mask=f_id, keypoint=f_id, bbox=f_id, name="gaussian_contrast", ) def neglog_fn(images: np.ndarray, epsilon: float = 0.001) -> np.ndarray: """Take the negative log transform of an intensity image. Args: image (np.ndarray): [N,H,W,C] array of intensity images. epsilon (float, optional): positive offset from 0 before taking the logarithm. Returns: np.ndarray: the image or images after a negative log transform. """ # shift image to avoid invalid values images += images.min(axis=(1, 2), keepdims=True) + epsilon # negative log transform images = -np.log(images) return images def neglog_aug(epsilon: float = 0.001) -> A.Lambda: """Take the negative log transform of an intensity image. Args: """ def f_image(images: np.ndarray, **kwargs) -> np.ndarray: return neglog_fn(images, epsilon) def f_id(x, **kwargs): return x return A.Lambda( image=f_image, mask=f_id, keypoint=f_id, bbox=f_id, name="neglog", ) def window_( images: np.ndarray, lower: SampleArg = 0.01, upper: SampleArg = 0.99, convert: bool = True, ) -> np.ndarray: """Apply a random window to an intensity image. Args: images (np.ndarray): [H,W,C] image upper (float, optional): The upper quantile of the window. Defaults to 0.99. lower (float, optional): The lower quantile of the window. Defaults to 0.01. Returns: np.ndarray: the image or images after having a random window applied. """ eps = 1e-7 upper = sample(upper) upper = np.quantile(images, upper) lower = sample(lower) lower = np.quantile(images, lower) if upper == lower: upper = images.max() lower = images.min() images = images - lower images = images / (upper - lower + eps) images = np.clip(images, 0, 1) if convert: images = (images * 255).astype(np.uint8) return images def window( lower: SampleArg = 0.01, upper: SampleArg = 0.99, convert: bool = True, ): """Apply a random window to intensity images. Args: upper (float, optional): The upper quantile of the window. Defaults to 0.99. lower (float, optional): The lower quantile of the window. Defaults to 0.01. Returns: np.ndarray: the image or images after having a random window applied. """ def _window(images: np.ndarray, **kwargs) -> np.ndarray: return window_(images, upper, lower, convert=convert) def f_id(x, **kwargs): return x return A.Lambda( image=_window, mask=f_id, keypoint=f_id, bbox=f_id, name="window", ) def build_augmentation(train: bool = True, img_size: int = 448) -> A.SomeOf: """Build an augmentation pipeline. Args: train: Whether to build an augmentation for training or testing. If True, the wrapped function is used to get the training augmentations. annotations: Whether the dataset contains annotations. image_size: The size to resize images to. If None, no resizing is done. normalize: Whether to normalize the image to [-1, 1]. """ if not train: return A.Compose( [neglog_aug(), window(0.01, 0.95, convert=False), A.Resize(img_size, img_size)] ) return A.Compose( [ neglog_aug(), window((0, 0.05), (0.95, 1.0), convert=True), A.Resize(img_size, img_size), A.CLAHE(clip_limit=(1, 4), p=0.5), A.InvertImg(p=0.5), A.SomeOf( [ A.OneOf( [ A.GaussianBlur((3, 5)), A.MotionBlur(blur_limit=(3, 5)), A.MedianBlur(blur_limit=5), ], ), A.OneOf( [ A.Sharpen(alpha=(0.2, 0.5)), A.Emboss(alpha=(0.2, 0.5)), ], ), A.OneOf( [ A.MultiplicativeNoise(multiplier=(0.9, 1.1)), A.HueSaturationValue( hue_shift_limit=20, sat_shift_limit=30, val_shift_limit=20, ), A.RandomBrightnessContrast( brightness_limit=(-0.4, 0.2), contrast_limit=(-0.4, 0.2) ), gaussian_contrast_aug( alpha=(0.6, 1.4), sigma=(0.1, 0.5), max_value=255 ), ], ), A.RandomToneCurve(scale=0.1), A.OneOf( [ A.RandomShadow(), A.RandomFog(fog_coef_lower=0.1, fog_coef_upper=0.3, alpha_coef=0.08), ], ), A.OneOf( [ Dropout(dropout_prob=0.05), CoarseDropout( max_holes=12, max_height=24, max_width=24, min_holes=4, min_height=4, min_width=4, ), ], p=3, ), ], n=np.random.randint(0, 5), replace=False, ), A.Normalize(mean=[0, 0, 0], std=[1, 1, 1], max_pixel_value=255), # Normalize to [0, 1] ], ) def load_image(path: Path) -> np.ndarray: return np.array(Image.open(path)) def _shift(category_id: int, fragment_id: int) -> int: return 10 * (category_id - 1) + fragment_id def masks_to_seg(masks: np.ndarray, category_ids: list[int], fragment_ids: list[int]) -> np.ndarray: """Convert masks to a binary-encoded multi-label segmentation. Binarizes the segmentation at each pixel by left shifting the one-hot mask by 10 * (category_id - 1) + (fragment_id) Args: masks (np.ndarray): [n, h, w] boolean masks. category_ids (list[int]): [n] integer category IDs, in SA (1), LI (2) or RI (3). fragment_ids (list[int]): [n] integer fragment IDs, in [1,10]. Returns: np.ndarray: [h, w] uint32 segmentation, where each pixel is a 32-bit integer encoding the whether the """ seg = np.zeros((masks.shape[1], masks.shape[2]), dtype=np.uint32) masks = masks.astype(np.uint32) for mask, category_id, fragment_id in zip(masks, category_ids, fragment_ids): seg = np.bitwise_or(seg, np.left_shift(mask, _shift(category_id, fragment_id))) return seg def seg_to_masks(seg: np.ndarray) -> tuple[np.ndarray, list[int], list[int]]: """Convert a binary-encoded multi-label segmentation to masks.""" category_ids = [] fragment_ids = [] masks = [] for category_id in CATEGORIES.values(): for fragment_id in range(1, 11): mask = np.right_shift(seg, _shift(category_id, fragment_id)) & 1 if mask.sum() > 0: masks.append(mask) category_ids.append(category_id) fragment_ids.append(fragment_id) return np.array(masks), category_ids, fragment_ids def load_masks(path: Path) -> tuple[np.ndarray, list[int], list[int]]: seg = np.array(Image.open(path)) return seg_to_masks(seg) def neglog_window(image: np.ndarray, epsilon: float = 0.01) -> np.ndarray: """Take the negative log transform of an intensity image. Args: image (np.ndarray): a single 2D image. epsilon (float, optional): positive offset from 0 before taking the logarithm. Returns: np.ndarray: the image or images after a negative log transform, scaled to [0, 1] """ image = np.array(image) shape = image.shape if len(shape) == 2: image = image[np.newaxis, :, :] # shift image to avoid invalid values image += image.min(axis=(1, 2), keepdims=True) + epsilon # negative log transform image = -np.log(image) # linear interpolate to range [0, 1] image_min = image.min(axis=(1, 2), keepdims=True) image_max = image.max(axis=(1, 2), keepdims=True) if np.any(image_max == image_min): print( f"mapping constant image to 0. This probably indicates the projector is pointed away from the volume." ) image[:] = 0 if image.shape[0] > 1: print("TODO: zeroed all images, even though only one might be bad.") else: image = (image - image_min) / (image_max - image_min) if np.any(np.isnan(image)): print(f"got NaN values from negative log transform.") if len(shape) == 2: return image[0] else: return image def as_uint8(image: np.ndarray) -> np.ndarray: """Convert the image to uint8. Args: image (np.ndarray): the image to convert. Returns: np.ndarray: the converted image. """ if image.dtype in [np.float16, np.float32, np.float64]: image = np.clip(image * 255, 0, 255).astype(np.uint8) elif image.dtype == bool: image = image.astype(np.uint8) * 255 elif image.dtype != np.uint8: print(f"Unknown image type {image.dtype}. Converting to uint8.") image = image.astype(np.uint8) return image def as_float32(image: np.ndarray) -> np.ndarray: """Convert the image to float32. Args: image (np.ndarray): the image to convert. Returns: np.ndarray: the converted image. """ if image.dtype in [np.float16, np.float32, np.float64]: image = image.astype(np.float32) elif image.dtype == bool: image = image.astype(np.float32) elif image.dtype != np.uint8: print(f"Unknown image type {image.dtype}. Converting to float32.") image = image.astype(np.float32) else: image = image.astype(np.float32) / 255 return image def visualize_drr(image: np.ndarray) -> np.ndarray: """Process a raw DRR for visualization. Args: image (np.ndarray): The raw float32 DRR.""" # Cast to uint8 image = neglog_window(image) image = as_uint8(image) # apply clahe and invert clahe = cv2.createCLAHE(clipLimit=4, tileGridSize=(8, 8)) image = clahe.apply(image) image = 255 - image image = cv2.cvtColor(image, cv2.COLOR_BGR2RGB) return image def draw_masks( image: np.ndarray, masks: np.ndarray, alpha: float = 0.3, threshold: float = 0.5, names: Optional[list[str]] = None, colors: Optional[np.ndarray] = None, palette: str = "hls", seed: Optional[int] = None, ) -> np.ndarray: """Draw contours of masks on an image (copy). Args: image (np.ndarray): the image to draw on. masks (np.ndarray): the masks to draw. [num_masks, H, W] array of masks. """ image = as_float32(image) if image.ndim == 2: image = np.stack([image] * 3, axis=-1) if colors is None: colors = np.array(sns.color_palette(palette, masks.shape[0])) if seed is not None: np.random.seed(seed) colors = colors[np.random.permutation(colors.shape[0])] image *= 1 - alpha for i, mask in enumerate(masks): bool_mask = mask > threshold image[bool_mask] = colors[i] * alpha + image[bool_mask] * (1 - alpha) contours, _ = cv2.findContours( bool_mask.astype(np.uint8), cv2.RETR_EXTERNAL, cv2.CHAIN_APPROX_SIMPLE ) image = as_uint8(image) cv2.drawContours(image, contours, -1, (255 * colors[i]).tolist(), 1) image = as_float32(image) image = as_uint8(image) fontscale = 0.75 / 512 * image.shape[0] thickness = max(int(1 / 256 * image.shape[0]), 1) if names is not None: for i, mask in enumerate(masks): bool_mask = mask > threshold ys, xs = np.argwhere(bool_mask).T if len(ys) == 0: continue y = (np.min(ys) + np.max(ys)) / 2 x = (np.min(xs) + np.max(xs)) / 2 image = cv2.putText( image, names[i], (int(x) + 5, int(y) - 5), cv2.FONT_HERSHEY_SIMPLEX, fontscale, (255 * colors[i]).tolist(), thickness, cv2.LINE_AA, ) return image def visualize_sample(image, masks, category_ids, fragment_ids): """Visualize the image and masks.""" names = [ f"{LABELS[category_id]}-{fragment_id}" for category_id, fragment_id in zip(category_ids, fragment_ids) ] image = visualize_drr(image) return draw_masks(image, masks, names=names, seed=0) class Dataset: def __init__(self, root: Path, split: str, img_size: int = 448): self.root = Path(root).expanduser() self.split = split self.img_size = img_size assert self.split in ["train", "val", "test"] self.input_dir = self.root / self.split / "input" / "images" / "x-ray" self.output_dir = self.root / self.split / "output" / "images" / "x-ray" self.image_paths = sorted(self.input_dir.glob("*.tif")) def __len__(self, index: int): image_path = self.image_paths[index] seg_path = self.output_dir / image_path.name image = load_image(image_path) masks, category_ids, fragment_ids = load_masks(seg_path) track_ids = [ 1000 * cat_id + fragment_id for cat_id, fragment_id in zip(category_ids, fragment_ids) ] # Augmentation aug = build_augmentation(train=self.split == "train") augmented = aug(image=image, masks=masks, category_ids=track_ids) image = augmented["image"] masks = augmented["masks"] track_ids = augmented["category_ids"] category_ids = [track_id // 1000 for track_id in track_ids] fragment_ids = [track_id % 1000 for track_id in track_ids] return image, masks, category_ids, fragment_ids if __name__ == "__main__": import shutil import imageio.v3 as iio root = Path("/home/killeen/datasets/OneDrive/datasets/PENGWIN") image_path = root / Path("test/input/images/x-ray/122_0350.tif") mask_path = root / Path("test/output/images/x-ray/122_0350.tif") shutil.copy(str(mask_path), "images/seg1.tif") # tiff to masks image = load_image(image_path) masks, category_ids, fragment_ids = load_masks(mask_path) print(category_ids, fragment_ids) print(masks.shape) vis_image = visualize_sample(image, masks, category_ids, fragment_ids) vis_path = Path("images/sample_original.png") cv2.imwrite(str(vis_path), vis_image) print(f"Wrote image to {vis_path}") # masks to tiff seg_cycle = masks_to_seg(masks, category_ids, fragment_ids) seg_path = Path("images/seg2.tif") iio.imwrite(seg_path, seg_cycle) # Image.fromarray(seg_cycle).save(seg_path) print(f"Wrote segmentation to {seg_path}") # Images/seg2.tif and Images/seg1.tif should be the same masks, category_ids, fragment_ids = load_masks(seg_path) print(category_ids, fragment_ids) vis_image = visualize_sample(image, masks, category_ids, fragment_ids) cv2.imwrite("images/sample_cycle.png", vis_image) print(f"Wrote image to images/sample_cycle.png")