id stringlengths 36 36 | question stringlengths 8 990 | A stringlengths 1 284 | B stringlengths 1 250 | C stringlengths 1 278 ⌀ | D stringlengths 1 297 ⌀ | choice_num int64 2 9 | target stringclasses 6
values | category int64 1 3 | E stringlengths 1 604 ⌀ | F stringclasses 14
values | G stringclasses 3
values | H stringclasses 3
values | I stringclasses 1
value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
c899f28d-52ed-5906-bad3-9f38ce1f6fcf | Which of the following signs is NOT seen in patients suffering from thyrotoxicosis in whom thyroid storm is suspected | Tachycardia | Altered consciousness | Hypothermia | Weakness | 4 | C | 1 | null | null | null | null | null |
161e3c7d-43f1-5a26-bb64-4a0178e0ffa5 | Which of the following features of chronic morphine therapy is NOT subject to tolerance? | Analgesia | Respiratory depression | Constipation | All are subject to tolerance | 4 | C | 1 | null | null | null | null | null |
7fe35591-b10c-5a37-b96b-fe0dbc1f1341 | A 78-year-old woman with a history of reactive airway disease takes cimetidine (Tagamet) 400 mg at night. An additional dose is given IV 30 minutes before induction of anesthesia for an exploratory laparotomy. Possible side effects associated with this drug include all of the following EXCEPT | Bradycardia | Delayed awakening | Confusion | Increased metabolism of diazepam | 4 | D | 1 | null | null | null | null | null |
0229d493-9767-5823-aeb8-f717c0a7837f | Intraoperative allergic reactions are LEAST common after patient exposure to | Ketamine | Latex | Muscle relaxants | Hydroxyethyl starch | 4 | A | 1 | null | null | null | null | null |
f6e847da-a045-54a1-a242-9e6e572ff9e9 | Which of the following medications would be useful in the definitive treatment of sarin nerve gas poisoning? | Sodium nitroprusside | Methylene blue | Atropine | All the above are useful | 4 | C | 1 | null | null | null | null | null |
266f183c-34ea-5596-9918-ff645f47a386 | Alfentanil | Has a more rapid onset of action compared with fentanyl | Has a longer duration of action compared with fentanyl | Is 250 times more potent than fentanyl | Is excreted unchanged in the urine | 4 | A | 1 | null | null | null | null | null |
3a26e7c7-09e0-5d75-bd9f-1712d0ca6799 | Which of the following medications is NOT useful in the immediate management of status asthmaticus? | Terbutaline | Subcutaneous (SQ) epinephrine | Magnesium sulfate | Cromolyn | 4 | D | 1 | null | null | null | null | null |
2c36df4f-e115-5f8f-836b-9021b9404073 | Clonidine | Is an α2 blocker | Increases CNS sympathetic response to painful stimuli | Can be given orally as well as intravenously, but notepidurally or intrathecally | Decreases postanesthetic shivering | 4 | D | 1 | null | null | null | null | null |
d6001d54-702d-5223-b53d-9f2911b5b323 | The plasma half-time of which of the following drugs is prolonged in patients with end-stage cirrhotic liver disease? | Diazepam | Pancuronium | Alfentanil | All are prolonged | 4 | D | 1 | null | null | null | null | null |
314cafa0-c2e5-52ac-a6cd-e6afe7b9da14 | A 24-year-old, 100-kg patient is brought to the emergency room by the fire department after suffering smoke inhalation and third-degree burns on the abdomen, chest, and thighs 30 minutes earlier. The best muscle relaxant choice for the most rapid intubation would be | 2 mg vecuronium followed by succinylcholine | 1 mg of vecuronium, then 2 to 4 minutes later, 9 mg vecuronium | Rocuronium | Succinylcholine | 4 | D | 2 | null | null | null | null | null |
372190c4-1a90-53b3-a91b-0f4d43881a45 | Clonidine is useful in each of the following applications EXCEPT | Reducing BP with pheochromocytoma | Treatment of postoperative shivering | Protection against perioperative myocardial ischemia | As an agent for prolonging a bupivacaine spinal | 4 | A | 1 | null | null | null | null | null |
09c08768-f279-55d4-a779-113c28ec532d | A 79-year-old man is brought to the operating room for elective repair of bilateral inguinal hernias. The patient has a history of awareness during general anesthesia and refuses regional anesthesia. The patient is preoxygenated before induction of general anesthesia; 5 mg of midazolam and 250 mg of fentanyl are admini... | Flumazenil | Naloxone | Succinylcholine | Albuterol | 4 | C | 2 | null | null | null | null | null |
a5d42527-aa97-5609-932d-5813f485957b | Respiratory depression is LEAST after the induction dose of which of the following drugs? | Etomidate | Ketamine | Fentanyl | Propofol | 4 | B | 1 | null | null | null | null | null |
863eeecd-61ad-5b94-8e0e-b7ec38b24fc3 | A 64-year-old man with colon cancer is anesthetized for hepatic resection of liver metastases. Medical history is significant for ileal conduit surgery for bladder cancer, diabetes treated with glyburide, 50 pack-per-year smoking history, and family history of Malignant hyperthermia. Anesthesia is provided with morphin... | Excessive infusion of normal saline | Renal tubular acidosis | Propofol infusion syndrome | Diabetic ketoacidosis (DKA) | 4 | C | 3 | null | null | null | null | null |
997c4b45-e59d-568a-a615-37da0fe3d18e | Treatment of neuroleptic malignant syndrome (NMS) may be carried out with administration of the following drugs EXCEPT | Amantadine | Dantrolene | Bromocriptine | Physostigmine | 4 | D | 1 | null | null | null | null | null |
21ef59ab-9b7e-5517-8d5a-66c363ffc7c7 | A patient with a normal quantity of pseudocholinesterase (plasma cholinesterase) has a dibucaine number of 57. A 1 mg/kg dose of intravenous succinylcholine would likely result in | Hyperkalemic cardiac arrest | Paralysis lasting 5 to 10 minutes | Paralysis lasting 20 to 30 minutes | Paralysis lasting more than 1 to 3 hours | 4 | C | 2 | null | null | null | null | null |
cb600a06-cac4-5da9-a8fe-4793198b09b7 | Aprepitant exerts its pharmacologic effect by interaction with which receptor? | Neurokinin-1 (NK1 ) | 5-HT3 | Histamine (H1 ) | Dopamine (D2 ) | 4 | A | 1 | null | null | null | null | null |
6e7c0435-76ba-537e-972f-44583b7bc08c | A prolonged neuromuscular block with succinylcholine can be seen in all of the following patients EXCEPT those | Chronically exposed to malathion | Treated with echothiophate for glaucoma | Treated with cyclophosphamide for metastatic cancer | Having a C5 isoenzyme variant | 4 | D | 1 | null | null | null | null | null |
c557efe4-8c04-5872-9a76-c49e63a305dd | Which of the following statements concerning midazolam is FALSE? | Midazolam has greater amnestic than sedative properties | Its breakdown is inhibited by cimetidine | It produces retrograde amnesia | It facilitates the actions of the inhibitory neurotransmitter γaminobutyric acid (GABA) in the CNS | 4 | C | 1 | null | null | null | null | null |
d8563270-6af2-5574-a59d-96e80bd2d0ca | After a 2-hour vertical gastric banding procedure under desflurane, oxygen, and remifentanil anesthesia, the trocar is removed and the wound is closed. Upon emergence, the most likely scenario is | Adequate analgesia for 2 hours | Delayed emergence from narcotic | Pain | Respiratory depression in postanesthesia care unit (PACU) | 4 | C | 2 | null | null | null | null | null |
1d8d3d58-2ec6-5c84-8fe2-0e3eab1089e9 | An oral surgeon is about to perform a full mouth extraction on a 70-kg, 63-year-old man under conscious sedation. What is the maximum dose of lidocaine with epinephrine that he can safely infiltrate? | 200 mg | 300 mg | 400 mg | 500 mg | 4 | D | 2 | null | null | null | null | null |
20fcb5e4-48c8-5f77-9a9f-f27d5d15d2c1 | Postanesthetic shivering can be treated with all of the following EXCEPT | Naloxone | Physostigmine | Magnesium sulfate | Dexmedetomidine | 4 | A | 1 | null | null | null | null | null |
25d5b321-0618-51ba-8962-40eb4469ab03 | The main disadvantage of Sugammadex compared with neostigmine is | Recurarization | Contraindicated with renal failure | Not effective with benzylisoquinolinium relaxants | High incidence of allergic reactions | 4 | C | 1 | null | null | null | null | null |
cf95aba4-7432-5290-879a-38b5c0863af9 | Which of the biologic substances listed below is by itself the greatest determinant of serum osmolality? | AVP (arginine vasopressin) | Angiotensin I | Aldosterone | Renal prostaglandins (PGE2 ) | 4 | A | 1 | null | null | null | null | null |
59c6e720-3bc7-50b9-9c71-73546bd4a3cf | Remimazolam | Is less potent than its main metabolite | Is suitable for patients with liver disease | Is metabolized rapidly by amine precursor uptake and decarboxylation (APUD) cells in the gastrointestinal (GI) tract | Is a commercially available mixture of remifentanil plus midazolam | 4 | B | 1 | null | null | null | null | null |
aa84ae40-9a68-5a9e-95e3-4bdb28488b5d | Amrinone | Is a positive inotropic drug | Is antagonized by esmolol | Is a vasoconstrictor | All the above | 4 | A | 1 | null | null | null | null | null |
39a9a323-83de-548c-916c-aa110e2ea99c | Which statement concerning tricyclic antidepressants in patients receiving general anesthesia is TRUE? | They should be discontinued 2 weeks before elective operations | They may decrease the requirement for volatile anesthetics (decrease MAC) | Meperidine may produce hyperpyrexia in patients taking tricyclic antidepressants | They may exaggerate the response to ephedrine | 4 | D | 1 | null | null | null | null | null |
d9282a8c-09ee-57e3-95ff-4461b9070272 | Which of the following types of insulin preparations has the fastest onset of action if administered subcutaneously? | Glargine (Lantus) | Lispro (Humalog) | Regular (Humulin-R) | NPH (Humulin-N) | 4 | B | 1 | null | null | null | null | null |
c0c616b7-28db-5efe-a7de-429faefce398 | Which of the following mechanisms best explains the anticoagulative properties of tirofiban? | Cyclooxygenase (COX) inhibition | Interaction with von Willebrand factor (vWF) | Interaction with antithrombin III | Enhanced anti-Xa activity | 4 | B | 1 | null | null | null | null | null |
b8adc1fd-8918-5568-bd91-79a7910cc261 | The duration of action of remifentanil is attributable to which mode of metabolism? | Spontaneous degradation in blood (Hofmann elimination) | Hydrolysis by nonspecific plasma esterases | Hydrolysis by pseudocholinesterase | Rapid metabolism in the large intestine | 4 | B | 1 | null | null | null | null | null |
e8c06a11-417b-591e-a557-ebd39bdad474 | Pain at the intravenous site is LEAST with which IV drug? | Diazepam | Etomidate | Ketamine | Propofol | 4 | C | 1 | null | null | null | null | null |
c4e89e85-6cfa-5f5b-9ce8-76a0f8aff96b | A 35-year-old patient with a history of grand mal seizures is anesthetized for thyroid biopsy under general anesthesia consisting of 4 mg midazolam with infusion of propofol (150 μg/kg/min) and remifentanil (1 μg/kg/min). The patient takes phenytoin for control of seizures. After 30 minutes, the infusion is stopped and... | Administer naloxone | Administer flumazenil | Administer naloxone and flumazenil | Ventilate by hand | 4 | D | 3 | null | null | null | null | null |
9421461c-9c7a-5fa1-8650-77672a6763cb | Which of the following α-antagonists produces an irreversible blockade? | Phentolamine | Prazosin | Phenoxybenzamine | Labetalol | 4 | C | 1 | null | null | null | null | null |
1bfd296f-a27b-5bfa-a7b0-c64b3ff11312 | Which of the following drugs should NOT be used in the treatment of severe bradycardia induced by an excess of the beta-adrenergic receptor blockade as a result from a propranolol overdose? | Atropine | Isoproterenol | Dopamine | Glucagon | 4 | C | 2 | null | null | null | null | null |
29f04fcd-303e-5a38-919a-7a3192aa875e | A dose of 150 mg of IV dantrolene is administered to a 24-year-old, 75 kg man in whom incipient MH is suspected. An expected consequence of this therapy would be | Muscle spasticity in the postoperative period | Hypothermia | Cardiac dysrhythmias | Diuresis | 4 | D | 1 | null | null | null | null | null |
fa401710-3e9e-5771-9171-bcc9e459962d | Atracurium differs from cisatracurium in which way? | Molecular weight | Formation of laudanosine | Histamine release | No renal metabolism | 4 | C | 1 | null | null | null | null | null |
4fb34f12-ce67-5344-88de-86f45ea108a2 | Signs and symptoms of opioid withdrawal include all of the following | Increased BP and heart rate | Seizures | Abdominal cramps | Jerking of the legs# Pharmacology and Pharmacokinetics of Intravenous Drugs | 4 | B | 1 | null | null | null | null | null |
e114f219-e519-53a4-8b4e-be506fc87f8d | The minimum alveolar concentration (MAC) is highest in neonates (0- 30 days old) versus other age groups with which of the following? | Isoflurane | Sevoflurane | Desflurane | N2O | 4 | B | 1 | null | null | null | null | null |
84b37e0b-f283-535e-b96c-0a0880d29842 | The rate of increase in the alveolar concentration of a volatile anesthetic relative to the inspired concentration (FA/FI) plotted against time is steep during the first moments of inhalation, with all volatile anesthetics. The reason for this observation is that | Volatile anesthetics reduce alveolar ventilation (Va) | There is minimal anesthetic uptake from the alveoli into pulmonary venous blood | Volatile anesthetics increase cardiac output initially | The volume of the anesthetic breathing circuit is small | 4 | B | 1 | null | null | null | null | null |
6f226fcd-ac13-5090-a85b-183e08868b8e | During spontaneous breathing, volatile anesthetics | Increase tidal volume (Vt) and decrease respiratory rate | Increase Vt and increase respiratory rate | Decrease Vt and decrease respiratory rate | Decrease Vt and increase respiratory rate | 4 | D | 1 | null | null | null | null | null |
2281c08e-dd1b-5221-ad57-c9aa59b5a1f1 | Which of the following can NOT be considered an advantage of lowflow anesthesia? | Conservation of fossil fuel | Less ozone depletion | Reduced room pollution | Conservation of absorbent | 4 | D | 1 | null | null | null | null | null |
99d0dc09-de47-5e14-9170-5a4ff529b902 | The main reason desflurane is not used for inhalation induction in clinical practice is because of | Its low blood/gas partition coefficient | Its propensity to produce hypertension in high concentrations | Its propensity to produce airway irritability | Its propensity to produce tachyarrhythmias | 4 | C | 1 | null | null | null | null | null |
c6fcd356-1155-558a-b126-26e9732cf9fd | A 24-year-old is undergoing open reduction of an ankle fracture under general anesthesia with sevoflurane, N2O, and O2 through a laryngeal mask airway (LMA). Just after the vaporizer dial is turned up to 2%, the patient begins spontaneously breathing, but the inspiratory valve is not fully closing. The likely result of... | N2O | CO2 | O2 | All of the above | 4 | B | 2 | null | null | null | null | null |
16dc4d35-f1c0-566e-b2ac-8310f4623b8c | Select the TRUE statement regarding blood pressure when 1.5 MAC N2O-isoflurane is substituted for 1.5 MAC isoflurane-oxygen. | Blood pressure is less than awake value but greater than that seen with isoflurane-O2 | Blood pressure is equal to awake value | Blood pressure is greater than awake value | Blood pressure is less than isoflurane-O2 pressure | 4 | A | 2 | null | null | null | null | null |
fc8e1026-5da9-5be1-bc7a-5d601acd20d6 | Which of the following volatile anesthetics decreases systemic vascular resistance? | Sevoflurane | Isoflurane | Desflurane | All of the above | 4 | D | 1 | null | null | null | null | null |
b959174d-1569-55df-9cc3-59d795833c86 | With which of the following inhalational agents is cardiac output moderately increased? | N2O | Sevoflurane | Desflurane | Isoflurane | 4 | A | 1 | null | null | null | null | null |
0f52df3c-7cc4-5ea9-8507-2ece3262269e | Select the FALSE statement about isoflurane (≤ 1 MAC). | May attenuate bronchospasm | Increases right atrial pressure | Decreases mean arterial pressure | Decreases cardiac output | 4 | D | 1 | null | null | null | null | null |
f5c8b44f-9c71-5733-9b88-702e9c603cb4 | Abrupt and large increases in the delivered concentration of which of the following inhalational anesthetics may produce transient increases in systemic blood pressure and heart rate? | Desflurane | Isoflurane | Sevoflurane | N2O | 4 | A | 1 | null | null | null | null | null |
f7cd9e0f-2e00-53bb-adaa-bea772b8dbb2 | Discontinuation of 1 MAC of which volatile anesthetic followed by immediate introduction of 1 MAC of which second volatile anesthetic would temporarily result in the greatest combined anesthetic potency? | Isoflurane followed by desflurane | Sevoflurane followed by desflurane | Desflurane followed by isoflurane | Desflurane followed by sevoflurane | 4 | A | 2 | null | null | null | null | null |
2013028b-8fcf-5830-9f64-25ff853e9e64 | Cardiogenic shock has the greatest impact on the rate of increase in Fa/Fi for which of the following volatile anesthetics? | Isoflurane | Desflurane | Sevoflurane | N2O | 4 | A | 2 | null | null | null | null | null |
4d262d28-1c2a-5a4c-9857-c7e33b2d5547 | The vessel-rich group receives what percent of the cardiac output? | 45% | 60% | 75% | 90% | 4 | C | 1 | null | null | null | null | null |
c5645fcb-714e-55f5-a06e-520a24d71eb7 | What percent desflurane is present in the vaporizing chamber of a desflurane vaporizer (pressurized to 1500 mm Hg and heated to 23° C)? | Nearly 100% | 85% | 65% | 45% | 4 | D | 2 | null | null | null | null | null |
f6fa22dd-1c4b-519c-b3e7-958e970a0199 | A 25-year-old man is undergoing lymph node dissection for testicular cancer under general anesthesia. He has received four courses of bleomycin. The sevoflurane vaporizer is set at 1.8%, the oxygen at 100 mL/min, and air at 900/mL/min. The Fio2 of the fresh gas flow is | 26% | 29% | 34% | 41% | 4 | B | 2 | null | null | null | null | null |
f33e2c2c-16c8-50d1-9f74-23680ab224aa | How would a right mainstem intubation affect the rate of increase in arterial partial pressure of volatile anesthetics? | It would be reduced to the same degree for all volatile anesthetics | It would be accelerated to the same degree for all volatile anesthetics | It would be reduced the most for highly soluble agents | It would be reduced the most for poorly soluble agents | 4 | D | 3 | null | null | null | null | null |
15b80bbc-fbd2-5891-83bd-0e0a58b58d51 | During a breast biopsy with the patient under general anesthesia, the end-tidal carbon dioxide (ETCO2 ) is 25 mm Hg on infrared | Mainstem intubation | Enormous dead space | Incipient cardiac arrest | Overventilation | 4 | A | 2 | null | null | null | null | null |
52ee1336-834c-5df7-a172-384639b98afb | Isoflurane, when administered to healthy patients in concentrations less than 1.0 MAC, will decrease all of the following EXCEPT | Cardiac output | Myocardial contractility | Stroke volume | Systemic vascular resistance | 4 | A | 1 | null | null | null | null | null |
b62d5115-92f9-5e88-9817-f19be7eace2d | Increased Va will accelerate the rate of rise of the Fa/Fi ratio the MOST for | Desflurane | Sevoflurane | Isoflurane | N2O | 4 | C | 2 | null | null | null | null | null |
4786b08e-ca39-5382-a812-016ba19dd5ff | Select the correct order from greatest to least for anesthetic requirement. | Adults > infants > neonates | Adults > neonates > infants | Infants > neonates > adults | Neonates > adults > infants | 4 | C | 1 | null | null | null | null | null |
64c66ed3-a85b-57ce-a3cf-50bbe22f5063 | Which of the following MOST closely determines anesthetic effect? | Volume percent administered to patient | Partial pressure at the level of the central nervous system (CNS) | Solubility in blood | End-tidal concentration | 4 | B | 1 | null | null | null | null | null |
63e61cb0-7419-527f-a607-f815b7a6905d | A 31-year-old moderately obese woman is receiving a general anesthetic for cervical spinal fusion. After induction and intubation, the patient is mechanically ventilated with isoflurane at a vaporizer setting of 2.4%. The N2O flow is set at 500 mL/min, and the oxygen flowmeter is set at 250 mL/min. The infrared spectro... | 0.85 MAC | 1.1 MAC | 1.8 MAC | 2.1 MAC | 4 | B | 2 | null | null | null | null | null |
9c20b4b8-ef1a-5183-a9f5-0acc90c58723 | The rate of induction of anesthesia with isoflurane would be slower than expected in patients | With anemia | With chronic renal failure | In shock | With a right-to-left intracardiac shunt | 4 | D | 2 | null | null | null | null | null |
b57f6b35-3af7-59c7-91ef-06f44625c3dd | Which of the antihypertensives below reduces MAC? | Lisinopril (Zestril) | Losartan (Cozaar) | Triamterene (Dyrenium) | Verapamil (Calan SR) | 4 | D | 1 | null | null | null | null | null |
ae1e7fc1-b048-5a70-96c8-a984c5d7838f | A left-to-right tissue shunt, such as arteriovenous fistula, physiologically most resembles which of the following? | A left-to-right intracardiac shunt | A right-to-left intracardiac shunt | Ventilation of unperfused alveoli | A pulmonary embolism | 4 | A | 1 | null | null | null | null | null |
fb892898-944d-501c-8ae3-46de27d15122 | A fresh gas flow rate of 2 L/min or greater is recommended for administration of sevoflurane because | The vaporizer cannot accurately deliver the volatile at lesser flow rates | It prevents the formation of fluoride ions | It prevents the formation of compound A | It diminishes rebreathing | 4 | D | 1 | null | null | null | null | null |
0428f289-3224-53ac-8f13-2773b756791c | Select the true statement regarding the arrangement of the reservoir (sump) and bypass chamber in the Datex-Ohmeda Anesthesia Delivery Unit. | All volatiles share a common sump and separate bypass chambers | Sevoflurane and isoflurane share a common sump and bypass chamber, and desflurane has its own | Sevoflurane and desflurane share a common sump and bypass chamber, and isoflurane has its own | All volatiles have independent sumps but share a common bypass chamber | 4 | D | 1 | null | null | null | null | null |
ab77497f-a6b5-5bff-9f69-a952c3804a8d | Smokers are MOST likely to show a mild but transient increase in airway resistance after intubation and general anesthesia with which of the following? | Isoflurane | Sevoflurane | Halothane | Desflurane | 4 | D | 1 | null | null | null | null | null |
cb55d95c-f768-5068-ab2c-49702c06a3bb | If a patient is anesthetized with 6% desflurane in a hyperbaric chamber at 1 atm and the pressure is increased to 2 atm, the desflurane dial should be set to which setting if the anesthesia provider wishes to maintain the anesthetic at the same level? | 3% | 6% | 12% | Cannot be determined without knowledge of Fio2 | 4 | A | 2 | null | null | null | null | null |
d7a1a332-0c1b-53dc-9b7f-080b8a18cf5c | Which of the following organs is NOT considered a member of the vessel-rich group? | Lungs | Brain | Heart | Kidney | 4 | A | 1 | null | null | null | null | null |
ea43b5b3-7962-5256-a1ac-b8b20421fc18 | In isovolumic normal human subjects, 1 MAC of isoflurane anesthesia depresses mean arterial pressure by approximately 25%. The single BEST explanation for this is | Reduction in heart rate | Venous pooling | Myocardial depression | Decreased systemic vascular resistance | 4 | D | 1 | null | null | null | null | null |
6da67c87-03b5-5823-8803-35de7ca57284 | If cardiac output and Va are doubled, the effect on the rate of rise of Fa/Fi for isoflurane compared with that which existed immediately before these interventions will be | Doubled | Somewhat increased | Unchanged | Somewhat decreased | 4 | B | 2 | null | null | null | null | null |
e7b11f9f-a017-592a-8663-1e4e1f563e70 | Which of the following characteristics of inhaled anesthetics most closely correlates with recovery from inhaled anesthesia? | Blood/gas partition coefficient | Brain/blood partition coefficient | Fat/blood partition coefficient | MAC | 4 | A | 1 | null | null | null | null | null |
5d1f5a75-38a8-5539-89f7-251f02ee50de | After a 12-hour 60% N2O-desflurane anesthetic, evidence of N2O can be best detected by histologic examination of | Bone marrow | Renal tubules | Hepatocytes | None of the above | 4 | A | 1 | null | null | null | null | null |
478be4c6-0e05-5c2f-a8cd-28197cca55ec | An unconscious, spontaneously breathing patient is brought to the operating room (OR) from the intensive care unit for wound débridement. Which of the following maneuvers would serve to slow induction of inhalational anesthesia through the tracheostomy? | Using isoflurane instead of sevoflurane (using MACequivalent inspired concentrations) | Increasing fresh gas flow from 2 to 6 L/min | Esmolol 30 mg intravenously | None of the above | 4 | A | 2 | null | null | null | null | null |
aaddbb38-c8c0-596b-9262-90cb2ec33450 | Which of the settings below would give the highest arterial oxygen concentration during inhalation induction of general anesthesia with sevoflurane? | | Oxygen 0L/min | Air 2L/min | N2O 0L/min | | | Oxygen 2L/min | Air 0L/min | N2O 2L/min | | | Oxygen 2L/min | Air 2L/min | N2O 9L/min | | | Oxygen 2L/min | Air 3.5L/min | N2O 0L/min | | 4 | B | 2 | null | null | null | null | null |
d2f9d1e5-71fd-57e7-bb2b-b590c45ddbd3 | If a patient were anesthetized 90 minutes with 1.25 MAC isoflurane followed by 30 minutes of 1.25 MAC sevoflurane anesthesia, wake-up would be | The same as 2 hours of isoflurane anesthesia | The same as 2 hours of sevoflurane anesthesia | Less than 2 hours of isoflurane anesthesia, but greater than 2 hours of sevoflurane | Greater than 2 hours of isoflurane anesthesia | 4 | A | 2 | null | null | null | null | null |
d51449f4-1a9c-51e1-9686-4c10915fd029 | An anesthesia circuit is primed in preparation for an inhalation induction (with open adjustable pressure-limiting valve). The anesthesia hose is occluded with a flow of 6 L/min. The anesthesia circuit (canisters, hoses, mask, anesthesia bag) contains 6 L. A machine malfunction allows administration of 100% N2O. Approx... | 32% | 48% | 63% | 86% | 4 | C | 2 | null | null | null | null | null |
b893871a-0736-55fc-958e-6ffb69e66887 | Which of the following factors lowers MAC for volatile anesthetics? | Serum sodium 151 mEq/L | Red hair | Body temperature 38° C | Acute ethanol ingestion | 4 | D | 1 | null | null | null | null | null |
7be65dd3-4ebc-5352-b2f2-9d99fd5e7790 | Each of the following factors can influence the partial pressure gradient necessary for the achievement of anesthesia EXCEPT | Inspired anesthetic concentration | Cardiac output | Va | Ventilation of nonperfused alveoli (dead space) | 4 | D | 3 | null | null | null | null | null |
72f4877a-0170-5ec3-b4a4-e264340ffa3f | Which of the following volatile anesthetics is unique in containing preservative? | Sevoflurane | Desflurane | Isoflurane | None of the above | 4 | D | 1 | null | null | null | null | null |
236e3024-5d25-55e1-a16e-f928334029f1 | If the alveolar-to-venous partial pressure difference of a volatile anesthetic (PA − Pv) is positive (i.e., PA > Pv) and the arterial-to-venous partial pressure difference (Pa − Pv) is negative (i.e., Pv > Pa), which of the following scenarios is MOST likely to be true? | The vaporizer has been shut off at the end of the case | Induction has just started | Steady state has been achieved | The vaporizer was shut off during emergence, then turned back on | 4 | D | 3 | null | null | null | null | null |
ef05abef-c604-548c-b041-555668866fa9 | Anesthetic loss to the plastic and rubber components of the anesthetic circuit, hindering achievement of an adequate inspired concentration, is a factor with which of the following anesthetics? | Desflurane | Isoflurane | Sevoflurane | N2O | 4 | B | 1 | null | null | null | null | null |
388991b7-92a9-5673-aa12-7aa16f704e1b | Factors predisposing to formation and/or rebreathing of compound A include each of the following EXCEPT | Low fresh gas flow | Use of calcium hydroxide lime versus soda lime | High absorbent temperatures | Fresh absorbent | 4 | B | 1 | null | null | null | null | null |
e4b80b1f-1e9e-5a43-b797-1bef7efc6158 | The following volatile agents are correctly matched with their degree of metabolism (determined by metabolite recovery): | Sevoflurane 2% | Isoflurane 0.2% | Desflurane 0.02% | All are correctly matched | 4 | D | 1 | null | null | null | null | null |
fa4ada1f-698c-5e24-9cd2-59498bfcbd87 | Which of the components below is NOT considered in the process of "washin" of the anesthesia circuit at the onset of administration? | Infrared spectrometer tubing and reservoir | Expiratory limb | Anesthesia bag | CO2 absorber | 4 | A | 1 | null | null | null | null | null |
1680c731-fd07-5d38-9a0c-dd4c992ad34c | Which of the following maneuvers would NOT increase the rate of an inhalation induction? | Giving the patient an inotropic infusion | Substituting sevoflurane for isoflurane | Overpressurizing | Carrying out the induction in San Diego instead of Denver | 4 | A | 2 | null | null | null | null | null |
87a5e5a4-e6b2-57ef-86ad-6dc438373ff8 | Which of the following anesthetics would undergo 90% elimination the most rapidly after a 6-hour Whipple procedure under 1 MAC for the | Isoflurane | Sevoflurane | Desflurane | Sevoflurane and desflurane are tied | 4 | C | 1 | null | null | null | null | null |
f8929926-01df-509e-bc06-604d2e3f8270 | After induction and intubation of a healthy patient and institution of a ventilator, the sevoflurane vaporizer is set at 2%, and fresh gas flow is 1 L/min (50% N2O and 50% O2 ). The inspired concentration on the infrared spectrometer 1 minute later is 1.4%. The MAIN reason for the difference between the dial setting an... | Rapid uptake of sevoflurane | Insufficient fresh gas flow for correct vaporizer function | Second gas effect | Dilution | 4 | D | 2 | null | null | null | null | null |
688399c0-3f15-5f5e-af9e-f12919d18a50 | After cessation of general anesthesia that consisted of air, oxygen, and a volatile agent only, the patient is given 100% oxygen. Each of the following serves as a reservoir for volatile anesthesia and may delay emergence EXCEPT | Rebreathed exhaled gases | The absorbent | The patient | Gases emerging from the common gas outlet | 4 | D | 1 | null | null | null | null | null |
d118e692-e187-5445-a9e5-bb8c2e3dfcd3 | Which of the following characteristics of volatile anesthetics is necessary for calculation of the time constant? | Blood/gas partition coefficient | Brain/blood partition coefficient | Oil/gas partition coefficient | All of the above | 4 | B | 1 | null | null | null | null | null |
59c02103-3431-53c9-8881-ec30c50365da | The concept of "context sensitive half-time" emphasizes the importance of the relationship between half-time and | Va | Blood solubility | Concentration | Duration | 4 | D | 1 | null | null | null | null | null |
5f90c270-1ac0-52fc-a138-d3a517d71b94 | Select the FALSE statement regarding pharmacokinetics for volatile anesthetics. After three time constants | 6 to 12 minutes have elapsed for "modern anesthetics" | The arterial-to-venous partial pressure difference (for the volatile) for the brain is very small | The expired volatile concentration will rise much less slowly than in the preceding 12 minutes | The venous blood will contain 95% of volatile content of arterial blood#### Directions(Questions 378 through 381): Match the inhalational agents with the characteristics to which they most closely correspond. Each lettered heading (A through D) may be selected once, more than once, or not at all. | 4 | D | 3 | null | null | null | null | null |
a985d88a-f509-5a2b-8ac6-9330e1ae42d5 | Each of the following treatments might be useful in decreasing a prolonged prothrombin time (PT) EXCEPT | Recombinant factor VIII | Vitamin K | Fresh frozen plasma (FFP) | Cryoprecipitate | 4 | A | 1 | null | null | null | null | null |
b1c5c9eb-cf48-5175-98a0-598c4c762873 | Which of the following practices for releasing platelets is most beneficial in avoiding future hemolytic reactions (from alloantibodies) in the recipient? | Serologic crossmatch | Extended phenotype matching | RhD matching | ABO matching | 4 | C | 2 | null | null | null | null | null |
a1dc0cd9-f00d-5c2e-a83e-e108fea85b43 | Which of the fluids below has the greatest osmolality? | Normal saline | Lactated Ringer solution | D5 ½NS normal saline | 5% Albumin | 4 | C | 2 | null | null | null | null | null |
2dc927a6-0c7d-558c-983f-4b9547648e27 | In a 70-kg patient, 1 dose of platelets (1 apheresis platelet or six pooled units of whole blood–derived platelets) should increase the platelet count by | 12,000 to 30,000/mm3 | 30,000 to 60,000/mm3 | 90,000 to 120,000/mm3 | 120,000 to 150,000/mm3 | 4 | B | 1 | null | null | null | null | null |
e207ce8b-37cc-54b3-b6fd-d0365c2a9936 | A 68-year-old patient receives a 1-unit transfusion of packed red blood cells (RBCs) in the recovery room after a laparoscopic prostatectomy. As the blood is slowly dripping into his peripheral intravenous line, the patient complains of itching on his chest and arms, but his vital signs remain stable. The antibody most... | Rh | ABO | MN, P, and Lewis | None of the above | 4 | D | 2 | null | null | null | null | null |
fe3aa550-acd0-5e38-aeef-5ffad84121ba | The likelihood of a clinically significant hemolytic transfusion reaction resulting from administration of type-specific blood is less than | 1 in 250 | 1 in 500 | 1 in 1000 | 1 in 10,000 | 4 | C | 1 | null | null | null | null | null |
821a316f-2b25-533a-837b-64e3c1aec7c3 | Which of the following is NOT tested in the first or immediate phase of blood crossmatching? | ABO | Rh | MN | Lewis | 4 | B | 1 | null | null | null | null | null |
8a3a99a9-7f63-5d12-b6e3-eee179d23d3d | Which of the following clotting factors has the shortest half-life? | Factor II | Factor V | Factor VII | Factor IX | 4 | C | 1 | null | null | null | null | null |
8500754e-5a15-5daa-82da-646c9f7c7db6 | Which of the measures below does NOT reduce the incidence of transfusion-related acute lung injury (TRALI)? | Exclusion of female donors | Use of autologous blood | Leukocyte reduction | Use of blood less than 14 days old | 4 | C | 1 | null | null | null | null | null |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.