prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Activation of MYMK in Hepatoma Cell Line causally result in response to virus? | 0 | 1,210 | Activation | MYMK | response to virus | Hepatoma Cell Line | Gene: MYMK (myomaker, myoblast fusion factor)
Type: protein-coding
Summary: Involved in myoblast fusion. Located in plasma membrane. Implicated in Carey-Fineman-Ziter syndrome. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: muscle organ development, myoblast fusion, myo... |
Does Knockout of RPL9 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 287 | Knockout | RPL9 | cell proliferation | Endometrial Cancer Cell Line | Gene: RPL9 (ribosomal protein L9)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ... |
Does Knockout of GKN2 in Cancer Cell Line causally result in cell proliferation? | 0 | 948 | Knockout | GKN2 | cell proliferation | Cancer Cell Line | Gene: GKN2 (gastrokine 2)
Type: protein-coding
Summary: The secretory protein encoded by this gene is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine-1. This gene may be a tumor suppressor gene, as its expression is markedly decreased in gastric ... |
Does Knockout of RPS7 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 787 | Knockout | RPS7 | cell proliferation | Gastric Cancer Cell Line | Gene: RPS7 (ribosomal protein S7)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ... |
Does Knockout of TSSK2 in Astrocytoma Cell Line causally result in cell proliferation? | 0 | 904 | Knockout | TSSK2 | cell proliferation | Astrocytoma Cell Line | Gene: TSSK2 (testis specific serine kinase 2)
Type: protein-coding
Summary: TSSK2 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM, Mar 2008].
Gene Ontology: BP: cell differentiation, protein autophosphorylation, p... |
Does Knockout of GRWD1 in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 1 | 763 | Knockout | GRWD1 | cell proliferation | Ewing's Sarcoma Cell Line | Gene: GRWD1 (glutamate rich WD repeat containing 1)
Type: protein-coding
Summary: This gene encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical role in ribosome biogenesis and may also play a role in histone methylation through interactions with ... |
Does Knockout of NUDC in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | NUDC | cell proliferation | Colorectal Cancer Cell Line | Gene: NUDC (nuclear distribution C, dynein complex regulator)
Type: protein-coding
Summary: This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during... |
Does Knockout of PTBP3 in Cancer Cell Line causally result in cell proliferation? | 0 | 193 | Knockout | PTBP3 | cell proliferation | Cancer Cell Line | Gene: PTBP3 (polypyrimidine tract binding protein 3)
Type: protein-coding
Summary: The protein encoded by this gene binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different iso... |
Does Knockout of WNK4 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 0 | 2,114 | Knockout | WNK4 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: WNK4 (WNK lysine deficient protein kinase 4)
Type: protein-coding
Summary: This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The... |
Does Knockout of FGF22 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 220 | Knockout | FGF22 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: FGF22 (fibroblast growth factor 22)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embry... |
Does Knockout of ZMAT1 in Cancer Cell Line causally result in cell proliferation? | 0 | 948 | Knockout | ZMAT1 | cell proliferation | Cancer Cell Line | Gene: ZMAT1 (zinc finger matrin-type 1)
Type: protein-coding
Summary: This gene encodes a protein containing Cys2-His2 (C2H2)-type zinc fingers, which are similar to those found in the nuclear matrix protein matrin 3. Alternatively spliced transcript variants have been found for this gene. [provided by ... |
Does Knockout of ADAT3 in acute lymphoblastic leukemia cell line causally result in cell proliferation? | 1 | 1,957 | Knockout | ADAT3 | cell proliferation | acute lymphoblastic leukemia cell line | Gene: ADAT3 (adenosine deaminase tRNA specific 3)
Type: protein-coding
Summary: This gene encodes a subunit of a tRNA-specific adenosine deaminase. This heterodimeric enzyme converts adenosine to inosine in the tRNA anticodon. A mutation in this gene causes a syndrome characterized by intellectual disab... |
Does Knockout of ICAM1 in Melanoma Cell Line causally result in response to chemicals? | 1 | 1,940 | Knockout | ICAM1 | response to chemicals | Melanoma Cell Line | Gene: ICAM1 (intercellular adhesion molecule 1)
Type: protein-coding
Summary: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as... |
Does Knockout of PRODH2 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 230 | Knockout | PRODH2 | cell proliferation | Gastric Cancer Cell Line | Gene: PRODH2 (proline dehydrogenase 2)
Type: protein-coding
Summary: The protein encoded by this gene catalyzes the first step in the catabolism of trans-4-hydroxy-L-proline, an amino acid derivative obtained through food intake and collagen turnover. One of the downstream products of this catabolism is... |
Does Knockout of UBE2M in Renal Cancer Cell Line causally result in cell proliferation? | 1 | 319 | Knockout | UBE2M | cell proliferation | Renal Cancer Cell Line | Gene: UBE2M (ubiquitin conjugating enzyme E2 M)
Type: protein-coding
Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enz... |
Does Knockout of ZNF85 in Cancer Cell Line causally result in cell proliferation? | 1 | 948 | Knockout | ZNF85 | cell proliferation | Cancer Cell Line | Gene: ZNF85 (zinc finger protein 85)
Type: protein-coding
Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. ... |
Does Knockout of RAB11FIP4 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 206 | Knockout | RAB11FIP4 | cell proliferation | Monocytic Leukemia Cell Line | Gene: RAB11FIP4 (RAB11 family interacting protein 4)
Type: protein-coding
Summary: The protein encoded by this gene interacts with RAB11 and is thought to be involved in bringing recycling endosome membranes to the cleavage furrow in late cytokinesis. Hypoxic conditions can lead to an upregulation of th... |
Does Knockout of NOP9 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | NOP9 | cell proliferation | Monocytic Leukemia Cell Line | Gene: NOP9 (NOP9 nucleolar protein)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in ribosome biogenesis. Predicted to be part of 90S preribosome and preribosome, small subunit precursor. Predicted to be active in nucleolus. [provided by Alliance of Genome Resource... |
Does Knockout of TMA16 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 951 | Knockout | TMA16 | cell proliferation | Colonic Cancer Cell Line | Gene: TMA16 (translation machinery associated 16 homolog)
Type: protein-coding
Summary: Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: ribosomal large subunit biogenesis, ribosome biogenesis; MF: preribosome binding, protein binding... |
Does Knockout of DDX52 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | DDX52 | cell proliferation | Monocytic Leukemia Cell Line | Gene: DDX52 (DExD-box helicase 52)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: maturation of SSU-rRNA; MF: ATP binding, ATP hydrolysis... |
Does Knockout of ZFP42 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 787 | Knockout | ZFP42 | cell proliferation | Gastric Cancer Cell Line | Gene: ZFP42 (ZFP42 zinc finger protein)
Type: protein-coding
Summary: Enables sequence-specific double-stranded DNA binding activity. Involved in female gonad development and male gonad development. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: fe... |
Does Knockout of PYGO2 in Monocytic Leukemia Cell Line causally result in response to chemicals? | 0 | 1,978 | Knockout | PYGO2 | response to chemicals | Monocytic Leukemia Cell Line | Gene: PYGO2 (pygopus family PHD finger 2)
Type: protein-coding
Summary: Predicted to enable several functions, including chromatin binding activity; histone acetyltransferase regulator activity; and histone binding activity. Predicted to be involved in kidney development and spermatid nucleus differenti... |
Does Knockout of INTS6 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 865 | Knockout | INTS6 | cell proliferation | Colonic Cancer Cell Line | Gene: INTS6 (integrator complex subunit 6)
Type: protein-coding
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA ... |
Does Knockout of C15orf32 in Melanoma Cell Line causally result in response to chemicals? | 1 | 1,940 | Knockout | C15orf32 | response to chemicals | Melanoma Cell Line | Gene: C15orf32 (chromosome 15 putative open reading frame 32)
Type: ncRNA
Summary: chromosome 15 putative open reading frame 32
Gene Ontology:
Pathways:
UniProt:
Entrez ID: 145858 |
Does Activation of AIP in T cell causally result in protein/peptide accumulation? | 0 | 2,426 | Activation | AIP | protein/peptide accumulation | T cell | Gene: AIP (AHR interacting HSP90 co-chaperone)
Type: protein-coding
Summary: The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is tr... |
Does Knockout of IKZF1 in T-lymphoma cell line causally result in cell proliferation? | 0 | 478 | Knockout | IKZF1 | cell proliferation | T-lymphoma cell line | Gene: IKZF1 (IKAROS family zinc finger 1)
Type: protein-coding
Summary: This gene encodes a transcription factor that belongs to the family of zinc-finger DNA-binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic sys... |
Does Knockout of OR52W1 in Chronic Myeloid Leukemia Cell Line causally result in response to chemicals? | 0 | 1,397 | Knockout | OR52W1 | response to chemicals | Chronic Myeloid Leukemia Cell Line | Gene: OR52W1 (olfactory receptor family 52 subfamily W member 1)
Type: protein-coding
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-prot... |
Does Knockout of POLD1 in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | POLD1 | cell proliferation | Colorectal Cancer Cell Line | Gene: POLD1 (DNA polymerase delta 1, catalytic subunit)
Type: protein-coding
Summary: This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alterna... |
Does Knockout of HELZ2 in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 519 | Knockout | HELZ2 | cell proliferation | Glioblastoma Cell Line | Gene: HELZ2 (helicase with zinc finger 2)
Type: protein-coding
Summary: The protein encoded by this gene is a nuclear transcriptional co-activator for peroxisome proliferator activated receptor alpha. The encoded protein contains a zinc finger and is a helicase that appears to be part of the peroxisome ... |
Does Knockout of ISCU in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 758 | Knockout | ISCU | cell proliferation | Endometrial Cancer Cell Line | Gene: ISCU (iron-sulfur cluster assembly enzyme)
Type: protein-coding
Summary: This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, a... |
Does Knockout of FNDC1 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,789 | Knockout | FNDC1 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: FNDC1 (fibronectin type III domain containing 1)
Type: protein-coding
Summary: Predicted to act upstream of or within several processes, including cellular response to hypoxia; positive regulation of cardiac muscle cell apoptotic process; and positive regulation of protein phosphorylation. Located... |
Does Knockout of CEPT1 in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | CEPT1 | cell proliferation | Colorectal Cancer Cell Line | Gene: CEPT1 (choline/ethanolamine phosphotransferase 1)
Type: protein-coding
Summary: This gene codes for a choline/ethanolaminephosphotransferase, which functions in the synthesis of choline- or ethanolamine- containing phospholipids. Alternative splicing results in multiple transcript variants. [provi... |
Does Knockout of SYF2 in T-lymphoma cell line causally result in cell proliferation? | 1 | 478 | Knockout | SYF2 | cell proliferation | T-lymphoma cell line | Gene: SYF2 (SYF2 pre-mRNA splicing factor)
Type: protein-coding
Summary: This gene encodes a nuclear protein that interacts with cyclin D-type binding-protein 1, which is thought to be a cell cycle regulator at the G1/S transition. Alternate transcriptional splice variants, encoding different isoforms, ... |
Does Knockout of GTPBP2 in T-lymphoma cell line causally result in cell proliferation? | 0 | 478 | Knockout | GTPBP2 | cell proliferation | T-lymphoma cell line | Gene: GTPBP2 (GTP binding protein 2)
Type: protein-coding
Summary: GTP-binding proteins, or G proteins, constitute a superfamily capable of binding GTP or GDP. G proteins are activated by binding GTP and are inactivated by hydrolyzing GTP to GDP. This general mechanism enables G proteins to perform a wi... |
Does Knockout of HSP90B1 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 897 | Knockout | HSP90B1 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: HSP90B1 (heat shock protein 90 beta family member 1)
Type: protein-coding
Summary: This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the e... |
Does Knockout of NLRP2 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 0 | 180 | Knockout | NLRP2 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: NLRP2 (NLR family pyrin domain containing 2)
Type: protein-coding
Summary: This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerizatio... |
Does Knockout of ZMYND12 in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,352 | Knockout | ZMYND12 | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: ZMYND12 (zinc finger MYND-type containing 12)
Type: protein-coding
Summary: Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: flagellated sperm motility, sperm axoneme assembly; MF: metal ion binding, protein binding, z... |
Does Knockout of AAK1 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,033 | Knockout | AAK1 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: AAK1 (AP2 associated kinase 1)
Type: protein-coding
Summary: This gene encodes a member of the SNF1 subfamily of serine/threonine protein kinases. Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-... |
Does Knockout of DNMT1 in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | DNMT1 | cell proliferation | Colorectal Cancer Cell Line | Gene: DNMT1 (DNA methyltransferase 1)
Type: protein-coding
Summary: This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi... |
Does Knockout of COX11 in Melanoma Cell Line causally result in cell proliferation? | 1 | 527 | Knockout | COX11 | cell proliferation | Melanoma Cell Line | Gene: COX11 (cytochrome c oxidase copper chaperone COX11)
Type: protein-coding
Summary: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 ... |
Does Knockout of MS4A15 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 80 | Knockout | MS4A15 | cell proliferation | Monocytic Leukemia Cell Line | Gene: MS4A15 (membrane spanning 4-domains A15)
Type: protein-coding
Summary: Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: membrane, plasma membrane
Pathways:
UniProt: Q8N5U1
Entrez ID: 219995 |
Does Knockout of MCM4 in Bladder Carcinoma causally result in cell proliferation? | 1 | 489 | Knockout | MCM4 | cell proliferation | Bladder Carcinoma | Gene: MCM4 (minichromosome maintenance complex component 4)
Type: protein-coding
Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex forme... |
Does Knockout of TSSK3 in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 519 | Knockout | TSSK3 | cell proliferation | Glioblastoma Cell Line | Gene: TSSK3 (testis specific serine kinase 3)
Type: protein-coding
Summary: This gene encodes a kinase expressed exclusively in the testis that is thought to play a role in either germ cell differentiation or mature sperm function. [provided by RefSeq, Jul 2008].
Gene Ontology: BP: cell differe... |
Does Knockout of ATP6AP1 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 1 | 2,119 | Knockout | ATP6AP1 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: ATP6AP1 (ATPase H+ transporting accessory protein 1)
Type: protein-coding
Summary: This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) a... |
Does Knockout of ZNF35 in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 0 | 1,246 | Knockout | ZNF35 | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: ZNF35 (zinc finger protein 35)
Type: protein-coding
Summary: Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in cellular response to retinoic acid; regulation of transcription by RNA polymerase II; and spermatogenesis. Located ... |
Does Knockout of ABCG5 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 427 | Knockout | ABCG5 | cell proliferation | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: ABCG5 (ATP binding cassette subfamily G member 5)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided int... |
Does Knockout of VPS52 in Cancer Cell Line causally result in cell proliferation? | 0 | 193 | Knockout | VPS52 | cell proliferation | Cancer Cell Line | Gene: VPS52 (VPS52 subunit of GARP complex)
Type: protein-coding
Summary: This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking... |
Does Knockout of PTH2 in Embryonic Kidney Cell Line causally result in protein/peptide accumulation? | 0 | 1,461 | Knockout | PTH2 | protein/peptide accumulation | Embryonic Kidney Cell Line | Gene: PTH2 (parathyroid hormone 2)
Type: protein-coding
Summary: This gene encodes the precursor of a peptide hormone that shares sequence similarity with the parathyroid hormone. This gene is expressed in various regions of the brain where it plays a role in the release of pituitary hormones, anxiety a... |
Does Knockout of TNC in Ovarian Cancer Cell Line causally result in cell proliferation? | 0 | 699 | Knockout | TNC | cell proliferation | Ovarian Cancer Cell Line | Gene: TNC (tenascin C)
Type: protein-coding
Summary: This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is impl... |
Does Knockout of RNMT in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 1 | 763 | Knockout | RNMT | cell proliferation | Ewing's Sarcoma Cell Line | Gene: RNMT (RNA guanine-7 methyltransferase)
Type: protein-coding
Summary: Enables RNA binding activity and mRNA (guanine-N7-)-methyltransferase activity. Involved in 7-methylguanosine mRNA capping. Located in fibrillar center and nucleoplasm. Part of mRNA cap binding activity complex; mRNA cap methyltr... |
Does Knockout of PINX1 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 758 | Knockout | PINX1 | cell proliferation | Endometrial Cancer Cell Line | Gene: PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1)
Type: protein-coding
Summary: Enables telomerase RNA binding activity and telomerase inhibitor activity. Involved in several processes, including negative regulation of DNA biosynthetic process; positive regulation of protein localization to ... |
Does Knockout of ATP2A2 in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 519 | Knockout | ATP2A2 | cell proliferation | Glioblastoma Cell Line | Gene: ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2)
Type: protein-coding
Summary: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of the skeletal muscle. This enzyme catalyzes the hydrolysis of ... |
Does Knockout of OR52K2 in Glioblastoma Cell Line causally result in response to chemicals? | 1 | 2,344 | Knockout | OR52K2 | response to chemicals | Glioblastoma Cell Line | Gene: OR52K2 (olfactory receptor family 52 subfamily K member 2)
Type: protein-coding
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-prot... |
Does Knockout of TUBG1 in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,996 | Knockout | TUBG1 | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: TUBG1 (tubulin gamma 1)
Type: protein-coding
Summary: This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleatio... |
Does Knockout of PPIAL4F in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | PPIAL4F | cell proliferation | Monocytic Leukemia Cell Line | Gene: PPIAL4F (peptidylprolyl isomerase A like 4F)
Type: protein-coding
Summary: Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding and protein peptidyl-prolyl isomerization. Predicted to be active in cytoplasm... |
Does Knockout of TOX3 in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,352 | Knockout | TOX3 | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: TOX3 (TOX high mobility group box family member 3)
Type: protein-coding
Summary: The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich d... |
Does Knockout of ALPL in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 220 | Knockout | ALPL | cell proliferation | Mammary Gland Tumor Cell Line | Gene: ALPL (alkaline phosphatase, biomineralization associated)
Type: protein-coding
Summary: This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissu... |
Does Knockout of RGPD6 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | RGPD6 | cell proliferation | Medulloblastoma Cell Line | Gene: RGPD6 (RANBP2 like and GRIP domain containing 6)
Type: protein-coding
Summary: Predicted to contribute to GTPase activator activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to be part of nuclear pore. Predicted to be active in cytoplasm. [provided by Alliance... |
Does Knockout of NCOR2 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 206 | Knockout | NCOR2 | cell proliferation | Monocytic Leukemia Cell Line | Gene: NCOR2 (nuclear receptor corepressor 2)
Type: protein-coding
Summary: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressor... |
Does Knockout of ETV3 in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 906 | Knockout | ETV3 | cell proliferation | Glioblastoma Cell Line | Gene: ETV3 (ETS variant transcription factor 3)
Type: protein-coding
Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation ... |
Does Knockout of LMAN1 in Hepatoma Cell Line causally result in response to virus? | 0 | 2,437 | Knockout | LMAN1 | response to virus | Hepatoma Cell Line | Gene: LMAN1 (lectin, mannose binding 1)
Type: protein-coding
Summary: The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotei... |
Does Knockout of DDX18 in Esophageal Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 334 | Knockout | DDX18 | cell proliferation | Esophageal Squamous Cell Carcinoma Cell Line | Gene: DDX18 (DEAD-box helicase 18)
Type: protein-coding
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiatio... |
Does Inhibition of EFR3A in Chronic Myeloid Leukemia Cell Line causally result in response to chemicals? | 1 | 1,184 | Inhibition | EFR3A | response to chemicals | Chronic Myeloid Leukemia Cell Line | Gene: EFR3A (EFR3 homolog A)
Type: protein-coding
Summary: The protein encoded by this gene is part of a complex that plays a role in maintaining an active pool of phosphatidylinositol 4-kinase (PI4K) at the plasma membrane. This protein is thought to be a peripheral membrane protein that associates wit... |
Does Knockout of XRCC3 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 305 | Knockout | XRCC3 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: XRCC3 (X-ray repair cross complementing 3)
Type: protein-coding
Summary: This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1... |
Does Knockout of NPLOC4 in Astrocytoma Cell Line causally result in cell proliferation? | 1 | 904 | Knockout | NPLOC4 | cell proliferation | Astrocytoma Cell Line | Gene: NPLOC4 (NPL4 homolog, ubiquitin recognition factor)
Type: protein-coding
Summary: Predicted to enable ATPase binding activity; ubiquitin binding activity; and ubiquitin protein ligase binding activity. Predicted to contribute to K48-linked polyubiquitin modification-dependent protein binding activ... |
Does Knockout of POGK in Endometrial Cancer Cell Line causally result in cell proliferation? | 0 | 758 | Knockout | POGK | cell proliferation | Endometrial Cancer Cell Line | Gene: POGK (pogo transposable element derived with KRAB domain)
Type: protein-coding
Summary: The exact function of the protein encoded by this gene is not known. However, this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus, and a transposase do... |
Does Knockout of FAM219B in Renal Cancer Cell Line causally result in cell proliferation? | 0 | 319 | Knockout | FAM219B | cell proliferation | Renal Cancer Cell Line | Gene: FAM219B (family with sequence similarity 219 member B)
Type: protein-coding
Summary: family with sequence similarity 219 member B
Gene Ontology:
Pathways:
UniProt: Q5XKK7
Entrez ID: 57184 |
Does Knockout of CWF19L2 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | CWF19L2 | cell proliferation | Medulloblastoma Cell Line | Gene: CWF19L2 (CWF19 like cell cycle control factor 2)
Type: protein-coding
Summary: Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of post-mRNA release spliceosomal complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: nucleoplasm, p... |
Does Knockout of SLU7 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 839 | Knockout | SLU7 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: SLU7 (spliceosome associated SLU7)
Type: protein-coding
Summary: Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It ass... |
Does Knockout of PLK4 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 1 | 180 | Knockout | PLK4 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: PLK4 (polo like kinase 4)
Type: protein-coding
Summary: This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Thre... |
Does Knockout of ATP8B3 in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 906 | Knockout | ATP8B3 | cell proliferation | Glioblastoma Cell Line | Gene: ATP8B3 (ATPase phospholipid transporting 8B3)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and... |
Does Knockout of FGF11 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 427 | Knockout | FGF11 | cell proliferation | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: FGF11 (fibroblast growth factor 11)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including emb... |
Does Knockout of PUSL1 in Endometrial Cancer Cell Line causally result in cell proliferation? | 0 | 758 | Knockout | PUSL1 | cell proliferation | Endometrial Cancer Cell Line | Gene: PUSL1 (pseudouridine synthase like 1)
Type: protein-coding
Summary: Predicted to enable pseudouridine synthase activity. Predicted to be involved in tRNA pseudouridine synthesis. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: RNA modifica... |
Does Knockout of MIR638 in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,396 | Knockout | MIR638 | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: MIR638 (microRNA 638)
Type: ncRNA
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I... |
Does Knockout of BUB3 in Cancer Cell Line causally result in cell proliferation? | 1 | 1,308 | Knockout | BUB3 | cell proliferation | Cancer Cell Line | Gene: BUB3 (BUB3 mitotic checkpoint protein)
Type: protein-coding
Summary: This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding... |
Does Knockout of TELO2 in Primary Effusion Lymphoma Cell Line causally result in response to chemicals? | 0 | 1,061 | Knockout | TELO2 | response to chemicals | Primary Effusion Lymphoma Cell Line | Gene: TELO2 (telomere maintenance 2)
Type: protein-coding
Summary: This gene encodes a protein that functions as an S-phase checkpoint protein in the cell cycle. The protein may also play a role in DNA repair.[provided by RefSeq, Mar 2009].
Gene Ontology: BP: 'de novo' cotranslational protein f... |
Does Knockout of PPP1R10 in Prostate Cancer Cell Line causally result in cell proliferation? | 1 | 843 | Knockout | PPP1R10 | cell proliferation | Prostate Cancer Cell Line | Gene: PPP1R10 (protein phosphatase 1 regulatory subunit 10)
Type: protein-coding
Summary: This gene encodes a protein phosphatase 1 binding protein. The encoded protein plays a role in many cellular processes including cell cycle progression, DNA repair and apoptosis by regulating the activity of protei... |
Does Knockout of DDX18 in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | DDX18 | cell proliferation | Colorectal Cancer Cell Line | Gene: DDX18 (DEAD-box helicase 18)
Type: protein-coding
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiatio... |
Does Knockout of ITGB7 in Melanoma Cell Line causally result in cell proliferation? | 1 | 527 | Knockout | ITGB7 | cell proliferation | Melanoma Cell Line | Gene: ITGB7 (integrin subunit beta 7)
Type: protein-coding
Summary: This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane ... |
Does Knockout of PSMC1 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 287 | Knockout | PSMC1 | cell proliferation | Endometrial Cancer Cell Line | Gene: PSMC1 (proteasome 26S subunit, ATPase 1)
Type: protein-coding
Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are co... |
Does Knockout of PIK3C3 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 387 | Knockout | PIK3C3 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: PIK3C3 (phosphatidylinositol 3-kinase catalytic subunit type 3)
Type: protein-coding
Summary: Enables 1-phosphatidylinositol-3-kinase activity. Involved in early endosome to late endosome transport and regulation of cytokinesis. Acts upstream of or within autophagy and protein lipidation. Located ... |
Does Knockout of SPATA31A6 in Bladder Carcinoma causally result in cell proliferation? | 1 | 489 | Knockout | SPATA31A6 | cell proliferation | Bladder Carcinoma | Gene: SPATA31A6 (SPATA31 subfamily A member 6)
Type: protein-coding
Summary: Predicted to enable actin binding activity. Predicted to be involved in cell differentiation and spermatogenesis. Predicted to be located in acrosomal vesicle. [provided by Alliance of Genome Resources, Apr 2022]
Gene ... |
Does Knockout of APOA4 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 787 | Knockout | APOA4 | cell proliferation | Gastric Cancer Cell Line | Gene: APOA4 (apolipoprotein A4)
Type: protein-coding
Summary: Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processin... |
Does Knockout of HMGCR in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 305 | Knockout | HMGCR | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase)
Type: protein-coding
Summary: HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the react... |
Does Knockout of IGF1R in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 149 | Knockout | IGF1R | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: IGF1R (insulin like growth factor 1 receptor)
Type: protein-coding
Summary: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor gene... |
Does Knockout of LSM5 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 865 | Knockout | LSM5 | cell proliferation | Colonic Cancer Cell Line | Gene: LSM5 (LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated)
Type: protein-coding
Summary: Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which c... |
Does Knockout of HSPA5 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | HSPA5 | cell proliferation | Medulloblastoma Cell Line | Gene: HSPA5 (heat shock protein family A (Hsp70) member 5)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. This protein localizes to the lumen of the endoplasmic reticulum (ER) where it operates as a typical HSP70 chaperone involved... |
Does Knockout of OSTC in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 287 | Knockout | OSTC | cell proliferation | Endometrial Cancer Cell Line | Gene: OSTC (oligosaccharyltransferase complex non-catalytic subunit)
Type: protein-coding
Summary: Predicted to contribute to dolichyl-diphosphooligosaccharide-protein glycotransferase activity. Predicted to be involved in protein N-linked glycosylation via asparagine. Part of oligosaccharyltransferase ... |
Does Knockout of RGPD6 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 230 | Knockout | RGPD6 | cell proliferation | Gastric Cancer Cell Line | Gene: RGPD6 (RANBP2 like and GRIP domain containing 6)
Type: protein-coding
Summary: Predicted to contribute to GTPase activator activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to be part of nuclear pore. Predicted to be active in cytoplasm. [provided by Alliance... |
Does Knockout of USP36 in Astrocytoma Cell Line causally result in cell proliferation? | 1 | 904 | Knockout | USP36 | cell proliferation | Astrocytoma Cell Line | Gene: USP36 (ubiquitin specific peptidase 36)
Type: protein-coding
Summary: This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitina... |
Does Knockout of CSTF3 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 815 | Knockout | CSTF3 | cell proliferation | Colonic Cancer Cell Line | Gene: CSTF3 (cleavage stimulation factor subunit 3)
Type: protein-coding
Summary: The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation... |
Does Knockout of RGL1 in Monocytic Leukemia Cell Line causally result in RNA accumulation? | 0 | 1,968 | Knockout | RGL1 | RNA accumulation | Monocytic Leukemia Cell Line | Gene: RGL1 (ral guanine nucleotide dissociation stimulator like 1)
Type: protein-coding
Summary: Predicted to be involved in regulation of catalytic activity. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: Ras protein signal transduct... |
Does Knockout of ECHDC3 in Non-Small Cell Lung Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,631 | Knockout | ECHDC3 | response to chemicals | Non-Small Cell Lung Adenocarcinoma Cell Line | Gene: ECHDC3 (enoyl-CoA hydratase domain containing 3)
Type: protein-coding
Summary: Predicted to enable enoyl-CoA hydratase activity. Involved in positive regulation of cellular response to insulin stimulus. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
... |
Does Knockout of ST20-MTHFS in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 1 | 2,119 | Knockout | ST20-MTHFS | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: ST20-MTHFS (ST20-MTHFS readthrough)
Type: protein-coding
Summary: This locus represents naturally occurring read-through transcription between the neighboring suppressor of tumorigenicity 20 and 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) genes on chromosome 15... |
Does Knockout of TBC1D21 in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,352 | Knockout | TBC1D21 | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: TBC1D21 (TBC1 domain family member 21)
Type: protein-coding
Summary: Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity and intracellular protein transport. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
... |
Does Knockout of USP53 in Primary Effusion Lymphoma Cell Line causally result in response to chemicals? | 0 | 1,061 | Knockout | USP53 | response to chemicals | Primary Effusion Lymphoma Cell Line | Gene: USP53 (ubiquitin specific peptidase 53)
Type: protein-coding
Summary: Predicted to enable thiol-dependent deubiquitinase. Predicted to be involved in response to auditory stimulus and sensory perception of sound. Predicted to act upstream of or within action potential and neuron apoptotic process.... |
Does Knockout of FBXO42 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,032 | Knockout | FBXO42 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: FBXO42 (F-box protein 42)
Type: protein-coding
Summary: Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A; MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquit... |
Does Knockout of PGBD4 in Chronic Myeloid Leukemia Cell Line causally result in response to chemicals? | 0 | 1,397 | Knockout | PGBD4 | response to chemicals | Chronic Myeloid Leukemia Cell Line | Gene: PGBD4 (piggyBac transposable element derived 4)
Type: protein-coding
Summary: The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genom... |
Does Knockout of RPS28 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 951 | Knockout | RPS28 | cell proliferation | Colonic Cancer Cell Line | Gene: RPS28 (ribosomal protein S28)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encode... |
Does Knockout of PNMA3 in Glioblastoma Cell Line causally result in response to chemicals? | 1 | 2,344 | Knockout | PNMA3 | response to chemicals | Glioblastoma Cell Line | Gene: PNMA3 (PNMA family member 3)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with ... |
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