prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of Nae1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity? | 1 | 2,171 | Knockout | Nae1 | tumorigenicity | Breast Adenocarcinoma Cell Line | Gene: Nae1 (NEDD8 activating enzyme E1 subunit 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, mitotic DNA replication checkpoint signaling, neuron apoptotic process, protein neddylation, regulation of apoptotic process, regulation of neuron apoptoti... |
Does Knockout of Gm128 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 161 | Knockout | Gm128 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Gm128 (predicted gene 128)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: regulation of cell population proliferation; CC: cellular_component, extracellular region
Pathways:
UniProt: Q569E4
Entrez ID: 229588 |
Does Knockout of Mrps9 in Regulatory T cell causally result in cell proliferation? | 0 | 2,127 | Knockout | Mrps9 | cell proliferation | Regulatory T cell | Gene: Mrps9 (mitochondrial ribosomal protein S9)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, translation; MF: RNA binding, structural constituent of ribosome; CC: intracellular organelle lumen, mitochondrial inner membrane, mitochondrial sma... |
Does Knockout of Fgf2 in breast epithelium causally result in cell cycle progression? | 0 | 1,468 | Knockout | Fgf2 | cell cycle progression | breast epithelium | Gene: Fgf2 (fibroblast growth factor 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: angiogenesis, angiogenesis involved in coronary vascular morphogenesis, behavioral response to ethanol, branching involved in ureteric bud morphogenesis, cardiac muscle cell proliferat... |
Does Knockout of Mien1 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,682 | Knockout | Mien1 | protein/peptide distribution | myoblast cell line | Gene: Mien1 (migration and invasion enhancer 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, negative regulation of apoptotic process, positive regulation of cell migration, positive regulation of filopodium assembly; CC: cytoplasm, cytoplasmic side ... |
Does Knockout of Epc1 in Pancreatic Cancer Cell Line causally result in response to chemicals? | 0 | 2,359 | Knockout | Epc1 | response to chemicals | Pancreatic Cancer Cell Line | Gene: Epc1 (enhancer of polycomb homolog 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell differentiation, chromatin organization, double-strand break repair via homologous recombination, double-strand break repair via nonhomologous end joining, negative regulation... |
Does Knockout of Acadvl in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 81 | Knockout | Acadvl | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Acadvl (acyl-Coenzyme A dehydrogenase, very long chain)
Type: protein-coding
Summary: This gene encodes a homodimeric mitochondrial flavoprotein and is a member of the acyl-CoA dehydrogenase family. Members of this family catalyze the first step of fatty acid beta-oxidation, forming a C2-C3 trans-... |
Does Knockout of Slc7a11 in breast epithelium causally result in cell cycle progression? | 0 | 1,470 | Knockout | Slc7a11 | cell cycle progression | breast epithelium | Gene: Slc7a11 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 11)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: L-cystine transport, L-glutamate import across plasma membrane, L-glutamate transmembrane transport, L-kynurenine transmembrane ... |
Does Knockout of Mettl21c in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,271 | Knockout | Mettl21c | cell proliferation | Mouse kidney carcinoma cell | Gene: Mettl21c (methyltransferase 21C, AARS1 lysine)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to dexamethasone stimulus, hormone-mediated apoptotic signaling pathway, methylation, protein methylation, regulation of release of sequestered calcium i... |
Does Knockout of Adgrf5 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,684 | Knockout | Adgrf5 | protein/peptide distribution | myoblast cell line | Gene: Adgrf5 (adhesion G protein-coupled receptor F5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, cell surface receptor signaling pathway, energy r... |
Does Knockout of Dbr1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 165 | Knockout | Dbr1 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Dbr1 (debranching RNA lariats 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA fragment catabolic process, RNA splicing, via transesterification reactions, mRNA processing, mRNA splicing, via spliceosome; MF: RNA lariat debranching enzyme activity, hydrolase a... |
Does Knockout of Ttc36 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Ttc36 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Ttc36 (tetratricopeptide repeat domain 36)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: central nervous system neuron development, memory, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, negative regulation of protein polyubiquit... |
Does Knockout of Uri1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,262 | Knockout | Uri1 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Uri1 (URI1, prefoldin-like chaperone)
Type: protein-coding
Summary: Predicted to enable several functions, including RNA polymerase II complex binding activity; phosphatase inhibitor activity; and transcription corepressor activity. Predicted to be involved in several processes, including intrinsi... |
Does Knockout of Dgcr2 in Mouse kidney carcinoma cell causally result in cell proliferation? | 1 | 1,290 | Knockout | Dgcr2 | cell proliferation | Mouse kidney carcinoma cell | Gene: Dgcr2 (DiGeorge syndrome critical region gene 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell adhesion, cognition, response to xenobiotic stimulus; CC: membrane
Pathways:
UniProt: P98154
Entrez ID: 13356 |
Does Knockout of Nkg7 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,681 | Knockout | Nkg7 | protein/peptide distribution | myoblast cell line | Gene: Nkg7 (natural killer cell group 7 sequence)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CD4-positive, alpha-beta T cell activation, defense response to protozoan, granzyme-mediated programmed cell death signaling pathway, inflammatory response, killing of cells ... |
Does Knockout of Rnf19b in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 161 | Knockout | Rnf19b | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Rnf19b (ring finger protein 19B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: adaptive immune response, immune system process, natural killer cell mediated cytotoxicity, protein autoubiquitination, protein ubiquitination, ubiquitin-dependent protein catabolic pro... |
Does Knockout of Cul9 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,289 | Knockout | Cul9 | cell proliferation | Mouse kidney carcinoma cell | Gene: Cul9 (cullin 9)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: microtubule cytoskeleton organization, protein ubiquitination, regulation of mitotic nuclear division, ubiquitin-dependent protein catabolic process; MF: ATP binding, metal ion binding, nucleotide bindi... |
Does Knockout of Spint2 in Regulatory T cell causally result in cell proliferation? | 0 | 2,127 | Knockout | Spint2 | cell proliferation | Regulatory T cell | Gene: Spint2 (serine protease inhibitor, Kunitz type 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: basement membrane organization, epithelial cell morphogenesis involved in placental branching, establishment or maintenance of cell polarity, negative regulation of cel... |
Does Knockout of Slx1b in Lymphoma Cell Line causally result in response to chemicals? | 0 | 1,532 | Knockout | Slx1b | response to chemicals | Lymphoma Cell Line | Gene: Slx1b (SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, double-strand break repair via homologous recombination, positive regulation of t-circl... |
Does Knockout of Ctdsp1 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,275 | Knockout | Ctdsp1 | cell proliferation | Colonic Cancer Cell Line | Gene: Ctdsp1 (CTD small phosphatase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of G1/S transition of mitotic cell cycle, negative regulation of neurogenesis, negative regulation of neuron differentiation, regulation of transcription by RNA poly... |
Does Knockout of Tubb2a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 82 | Knockout | Tubb2a | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Tubb2a (tubulin, beta 2A class IIA)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cerebral cortex development, microtubule cytoskeleton organization, microtubule-based process, mitotic cell cycle, neuron migration; MF: GTP binding, GTPase activity, metal ion bindi... |
Does Activation of Idnk in Mouse cell causally result in protein/peptide accumulation? | 1 | 690 | Activation | Idnk | protein/peptide accumulation | Mouse cell | Gene: Idnk (idnK gluconokinase homolog (E. coli))
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: ATP binding, gluconokinase activity, kinase activity, nucleotide binding, transferase activity
Pathways: Pentose phosphate pathway - Mus musculus (mouse)
Un... |
Does Knockout of Tor1b in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 2,477 | Knockout | Tor1b | cell proliferation | Embryonic Stem Cell Line | Gene: Tor1b (torsin family 1, member B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: endoplasmic reticulum organization, nuclear membrane organization, protein localization to nucleus; MF: ATP binding, ATP hydrolysis activity, hydrolase activity, identical protein bind... |
Does Knockout of Arhgap29 in Immortal mouse chromaffin cells causally result in cell viability? | 1 | 2,469 | Knockout | Arhgap29 | cell viability | Immortal mouse chromaffin cells | Gene: Arhgap29 (Rho GTPase activating protein 29)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of small GTPase mediated signal transduction, regulation of small GTPase mediated signal transduction, signal transduction; MF: GTPase activator activity,... |
Does Knockout of Stub1 in Melanoma Cell Line causally result in cell proliferation? | 1 | 1,158 | Knockout | Stub1 | cell proliferation | Melanoma Cell Line | Gene: Stub1 (STIP1 homology and U-Box containing protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, ERAD pathway, MAPK cascade, cellular response to heat, cellular response to hypoxia, cellular response to misfolded protein, chaper... |
Does Knockout of Fndc1 in breast epithelium causally result in cell cycle progression? | 0 | 1,470 | Knockout | Fndc1 | cell cycle progression | breast epithelium | Gene: Fndc1 (fibronectin type III domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to hypoxia, positive regulation of cardiac muscle cell apoptotic process, regulation of protein transport; CC: cell-cell junction, cytoplasm, extracell... |
Does Knockout of Mcm6 in breast epithelium causally result in cell cycle progression? | 0 | 1,470 | Knockout | Mcm6 | cell cycle progression | breast epithelium | Gene: Mcm6 (minichromosome maintenance complex component 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA replication, DNA replication initiation, double-strand break repair via break-induced replication, mitotic DNA replication, premeiotic DNA replication; MF: ATP ... |
Does Knockout of Prkra in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,267 | Knockout | Prkra | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Prkra (protein kinase, interferon inducible double stranded RNA dependent activator)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RISC complex assembly, antiviral innate immune response, cellular response to oxidative stress, ear development, miRNA processing, mi... |
Does Knockout of Scn10a in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,264 | Knockout | Scn10a | cell proliferation | Colonic Cancer Cell Line | Gene: Scn10a (sodium channel, voltage-gated, type X, alpha)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: AV node cell action potential, behavioral response to pain, bundle of His cell action potential, cardiac conduction, circadian rhythm, detection of mechanical stimu... |
Does Knockout of Tmbim6 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,681 | Knockout | Tmbim6 | protein/peptide distribution | myoblast cell line | Gene: Tmbim6 (transmembrane BAX inhibitor motif containing 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: IRE1-mediated unfolded protein response, apoptotic process, autophagy, calcium ion transmembrane transport, cellular response to unfolded protein, endoplasmic ret... |
Does Knockout of Top1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 83 | Knockout | Top1 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Top1 (topoisomerase (DNA) I)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA replication, DNA topological change, animal organ regeneration, cellular response to luteinizing hormone stimulus, chromatin remodeling, chromosome segregation, circadian regulation of ... |
Does Knockout of Ephx3 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 687 | Knockout | Ephx3 | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Ephx3 (epoxide hydrolase 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: epoxide metabolic process, lipid metabolic process; MF: catalytic activity, epoxide hydrolase activity, hydrolase activity; CC: endoplasmic reticulum, intracellular membrane-bounded organell... |
Does Knockout of Dnajb1 in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 579 | Knockout | Dnajb1 | cell proliferation | Embryonic Stem Cell Line | Gene: Dnajb1 (DnaJ heat shock protein family (Hsp40) member B1)
Type: protein-coding
Summary: This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in or... |
Does Knockout of Pla2g4f in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 165 | Knockout | Pla2g4f | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Pla2g4f (phospholipase A2, group IVF)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: arachidonate secretion, cellular response to antibiotic, fatty acid transport, glycerophospholipid catabolic process, lipid catabolic process, lipid metabolic process, phospholipid... |
Does Knockout of Fxn in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,262 | Knockout | Fxn | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Fxn (frataxin)
Type: protein-coding
Summary: Predicted to enable several functions, including 2 iron, 2 sulfur cluster binding activity; ferroxidase activity; and iron ion binding activity. Involved in [4Fe-4S] cluster assembly. Acts upstream of or within several processes, including adult walking... |
Does Knockout of Il1f10 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,679 | Knockout | Il1f10 | protein/peptide distribution | myoblast cell line | Gene: Il1f10 (interleukin 1 family, member 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to lipopolysaccharide, cytokine-mediated signaling pathway, immune response, inflammatory response; MF: cytokine activity, interleukin-1 receptor binding; CC: ... |
Does Knockout of Cyp2j12 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 81 | Knockout | Cyp2j12 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Cyp2j12 (cytochrome P450, family 2, subfamily j, polypeptide 12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: epoxygenase P450 pathway, icosanoid metabolic process, linoleic acid metabolic process, organic acid metabolic process, xenobiotic metabolic process; MF:... |
Does Knockout of Nup133 in Melanoma Cell Line causally result in cell proliferation? | 1 | 1,270 | Knockout | Nup133 | cell proliferation | Melanoma Cell Line | Gene: Nup133 (nucleoporin 133)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: animal organ development, mRNA export from nucleus, mRNA transport, nephron development, neural tube development, neurogenesis, nuclear pore organization, nucleocytoplasmic transport, paraxial ... |
Does Knockout of Pyroxd1 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 1,273 | Knockout | Pyroxd1 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Pyroxd1 (pyridine nucleotide-disulphide oxidoreductase domain 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to oxidative stress; MF: NAD(P)H oxidase H2O2-forming activity, molecular_function, oxidoreductase activity; CC: cytoplasm, nucleus, sa... |
Does Knockout of Ercc2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 82 | Knockout | Ercc2 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Ercc2 (excision repair cross-complementing rodent repair deficiency, complementation group 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, DNA-templated transcription, UV protection, apoptotic process, bone mineralization, central... |
Does Knockout of Tomm5 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,681 | Knockout | Tomm5 | protein/peptide distribution | myoblast cell line | Gene: Tomm5 (translocase of outer mitochondrial membrane 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein targeting to mitochondrion, protein transport; CC: membrane, mitochondrial outer membrane, mitochondrial outer membrane translocase complex, mitochondrion
... |
Does Knockout of Exosc8 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,682 | Knockout | Exosc8 | protein/peptide distribution | myoblast cell line | Gene: Exosc8 (exosome component 8)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA catabolic process, RNA processing, TRAMP-dependent tRNA surveillance pathway, U1 snRNA 3'-end processing, U4 snRNA 3'-end processing, U5 snRNA 3'-end processing, exonucleolytic trimming... |
Does Knockout of Timm8a1 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,681 | Knockout | Timm8a1 | protein/peptide distribution | myoblast cell line | Gene: Timm8a1 (translocase of inner mitochondrial membrane 8A1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein insertion into mitochondrial inner membrane, protein targeting to mitochondrion, protein transport; MF: identical protein binding, metal ion binding, zi... |
Does Knockout of Acin1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Acin1 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Acin1 (apoptotic chromatin condensation inducer 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, apoptotic chromosome condensation, apoptotic process, erythrocyte differentiation, mRNA processing, negative regulation of mRNA splicing, via spliceosome... |
Does Knockout of Phldb1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Phldb1 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Phldb1 (pleckstrin homology like domain, family B, member 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: basal cortex
Pathways:
UniProt: Q6PDH0
Entrez ID: 102693 |
Does Knockout of Fam83g in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 83 | Knockout | Fam83g | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Fam83g (family with sequence similarity 83, member G)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: BMP signaling pathway; CC: cytoplasm, cytosol, nucleus
Pathways:
UniProt: Q5SWY7
Entrez ID: 69640 |
Does Knockout of Trmt61a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 83 | Knockout | Trmt61a | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Trmt61a (tRNA methyltransferase 61A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA processing, mRNA processing, methylation, tRNA methylation, tRNA processing; MF: mRNA (adenine-N1-)-methyltransferase activity, methyltransferase activity, tRNA (adenine(58)-N1)... |
Does Knockout of C1qtnf4 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,684 | Knockout | C1qtnf4 | protein/peptide distribution | myoblast cell line | Gene: C1qtnf4 (C1q and tumor necrosis factor related protein 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell surface receptor signaling pathway via STAT, gene expression, positive regulation of interleukin-6 production, positive regulation of interleukin-6-mediate... |
Does Knockout of Emc10 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,287 | Knockout | Emc10 | cell proliferation | Mouse kidney carcinoma cell | Gene: Emc10 (ER membrane protein complex subunit 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: angiogenesis, positive regulation of angiogenesis, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, protein insert... |
Does Knockout of Map3k14 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 2,307 | Knockout | Map3k14 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: Map3k14 (mitogen-activated protein kinase kinase kinase 14)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: MAPK cascade, cellular response to mechanical stimulus, defense response to virus, immune response, non-canonical NF-kappaB signal transduction; MF: ATP bindi... |
Does Knockout of Vps29 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Vps29 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Vps29 (VPS29 retromer complex component)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Golgi to vacuole transport, endocytic recycling, intracellular protein transport, protein transport, retrograde transport, endosome to Golgi; MF: metal ion binding, protein bind... |
Does Knockout of Tnr in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 82 | Knockout | Tnr | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Tnr (tenascin R)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: associative learning, axon regeneration, cell adhesion, extracellular matrix organization, locomotory exploration behavior, long-term synaptic potentiation, modulation of chemical synaptic transmission... |
Does Knockout of Cenpp in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,262 | Knockout | Cenpp | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Cenpp (centromere protein P)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CENP-A containing chromatin assembly, biological_process, chromosome segregation; CC: chromosome, chromosome, centromeric region, inner kinetochore, nucleolus, nucleoplasm, nucleus
... |
Does Knockout of Slc30a9 in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 578 | Knockout | Slc30a9 | cell proliferation | Embryonic Stem Cell Line | Gene: Slc30a9 (solute carrier family 30 (zinc transporter), member 9)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: intracellular zinc ion homeostasis, monoatomic cation transmembrane transport, monoatomic cation transport, monoatomic ion transport, positive regulation ... |
Does Knockout of Nat10 in Microglial Cell Line causally result in response to virus? | 1 | 1,438 | Knockout | Nat10 | response to virus | Microglial Cell Line | Gene: Nat10 (N-acetyltransferase 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA modification, negative regulation of telomere maintenance via telomerase, positive regulation of translation, protein acetylation, rRNA acetylation involved in maturation of SSU-rRNA,... |
Does Knockout of Rps15a in Melanoma Cell Line causally result in cell proliferation? | 1 | 1,270 | Knockout | Rps15a | cell proliferation | Melanoma Cell Line | Gene: Rps15a (ribosomal protein S15A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, positive regulation of cell cycle, positive regulation of cell population proliferation, response to virus, ribosomal small subunit biogenesis, translation, tran... |
Does Knockout of A130010J15Rik in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,275 | Knockout | A130010J15Rik | cell proliferation | Colonic Cancer Cell Line | Gene: A130010J15Rik (RIKEN cDNA A130010J15 gene)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q9DAE8
Entrez ID: 319266 |
Does Knockout of Limk2 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,287 | Knockout | Limk2 | cell proliferation | Mouse kidney carcinoma cell | Gene: Limk2 (LIM domain kinase 2)
Type: protein-coding
Summary: Enables protein kinase activity. Acts upstream of or within several processes, including cornea development in camera-type eye; protein phosphorylation; and spermatogenesis. Located in cis-Golgi network and nucleus. Is expressed in several ... |
Does Knockout of Zfp318 in Immortal mouse chromaffin cells causally result in cell viability? | 1 | 2,469 | Knockout | Zfp318 | cell viability | Immortal mouse chromaffin cells | Gene: Zfp318 (zinc finger protein 318)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: meiotic cell cycle, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcription; MF: metal ion binding, nucleic acid binding, protein binding,... |
Does Knockout of Tubgcp5 in Embryonic Cell Line causally result in protein/peptide accumulation? | 1 | 1,152 | Knockout | Tubgcp5 | protein/peptide accumulation | Embryonic Cell Line | Gene: Tubgcp5 (tubulin, gamma complex component 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic microtubule organization, meiotic cell cycle, microtubule cytoskeleton organization, microtubule nucleation, mitotic cell cycle, spindle assembly; MF: gamma-tubu... |
Does Knockout of Ctsg in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 1,265 | Knockout | Ctsg | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Ctsg (cathepsin G)
Type: protein-coding
Summary: This gene encodes a member of the peptidase S1 (chymotrypsin) family of serine endopeptidases. The encoded preproprotein is proteolytically processed to generate a mature protein product. This product appears to play a role in host defense, includin... |
Does Knockout of Actr2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Actr2 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Actr2 (actin related protein 2)
Type: protein-coding
Summary: Predicted to enable cytoskeletal protein binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to contribute to actin filament binding activity. Acts upstream of or within several processes, including cel... |
Does Knockout of Cfap77 in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 2,477 | Knockout | Cfap77 | cell proliferation | Embryonic Stem Cell Line | Gene: Cfap77 (cilia and flagella associated protein 77)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, flagellated sperm motility; CC: axonemal B tubule inner sheath, axonemal microtubule, axoneme, cell projection, cellular_component, cilium, cytoplas... |
Does Knockout of Slco2b1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 688 | Knockout | Slco2b1 | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Slco2b1 (solute carrier organic anion transporter family, member 2b1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: bile acid and bile salt transport, cell population proliferation, cellular response to iron ion starvation, heme import into cell, intercellular tra... |
Does Knockout of Rpl22 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 82 | Knockout | Rpl22 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Rpl22 (ribosomal protein L22)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: alpha-beta T cell differentiation, cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: RNA binding, heparin binding, identical protein binding,... |
Does Knockout of Cdca5 in Lymphoma Cell Line causally result in response to chemicals? | 1 | 1,549 | Knockout | Cdca5 | response to chemicals | Lymphoma Cell Line | Gene: Cdca5 (cell division cycle associated 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell division, double-strand break repair, mitotic sister chromatid cohesion; MF: protein binding, protein-containing complex binding; CC: chromatin, chromosome, cytoplasm, nucl... |
Does Knockout of Lrrc34 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 687 | Knockout | Lrrc34 | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Lrrc34 (leucine rich repeat containing 34)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, cell differentiation, gene expression, telomere maintenance; CC: cellular_component, cytoplasm, nucleolus, nucleus
Pathways:
UniProt: Q9... |
Does Knockout of Thop1 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,681 | Knockout | Thop1 | protein/peptide distribution | myoblast cell line | Gene: Thop1 (thimet oligopeptidase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: intracellular signal transduction, peptide catabolic process, peptide metabolic process, proteolysis; MF: hydrolase activity, metal ion binding, metalloendopeptidase activity, metallopep... |
Does Knockout of Nhlh2 in Regulatory T cell causally result in cell proliferation? | 0 | 2,127 | Knockout | Nhlh2 | cell proliferation | Regulatory T cell | Gene: Nhlh2 (nescient helix loop helix 2)
Type: protein-coding
Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor bindin... |
Does Knockout of Sf3b6 in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 2,477 | Knockout | Sf3b6 | cell proliferation | Embryonic Stem Cell Line | Gene: Sf3b6 (splicing factor 3B, subunit 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, blastocyst formation, mRNA processing, mRNA splicing, via spliceosome; MF: RNA binding, mRNA binding, nucleic acid binding; CC: U12-type spliceosomal complex, U2-type... |
Does Knockout of Gbp2b in Embryonic Fibroblast Cell Line causally result in response to virus? | 1 | 1,133 | Knockout | Gbp2b | response to virus | Embryonic Fibroblast Cell Line | Gene: Gbp2b (guanylate binding protein 2b)
Type: protein-coding
Summary: Enables GMP binding activity and GTPase activity. Involved in cytolysis in another organism; positive regulation of defense response; and response to bacterium. Acts upstream of or within adhesion of symbiont to host; cellular resp... |
Does Knockout of Znhit6 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 1,265 | Knockout | Znhit6 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Znhit6 (zinc finger, HIT type 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: box C/D snoRNP assembly, maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), protein complex oligomerization, ribosome biogenesis, snoRNA localizat... |
Does Knockout of Lage3 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,275 | Knockout | Lage3 | cell proliferation | Colonic Cancer Cell Line | Gene: Lage3 (L antigen family, member 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: tRNA processing, tRNA threonylcarbamoyladenosine metabolic process; CC: EKC/KEOPS complex, cytoplasm, nuclear body, nucleoplasm, nucleus
Pathways:
UniProt: Q9CR70
... |
Does Knockout of Tnfrsf10b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 81 | Knockout | Tnfrsf10b | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Tnfrsf10b (tumor necrosis factor receptor superfamily, member 10b)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: TRAIL-activated apoptotic signaling pathway, apoptotic process, extrinsic apoptotic signaling pathway via death domain receptors, intrinsic apoptotic s... |
Does Knockout of Brix1 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,682 | Knockout | Brix1 | protein/peptide distribution | myoblast cell line | Gene: Brix1 (BRX1, biogenesis of ribosomes)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: rRNA processing, ribosomal large subunit assembly, ribosome biogenesis; MF: RNA binding, rRNA binding; CC: chromosome, nucleolus, nucleus
Pathways:
UniProt: Q9DC... |
Does Knockout of Ears2 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,682 | Knockout | Ears2 | protein/peptide distribution | myoblast cell line | Gene: Ears2 (glutamyl-tRNA synthetase 2, mitochondrial)
Type: protein-coding
Summary: This gene encodes a putative member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is enco... |
Does Knockout of Slc25a3 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 1,265 | Knockout | Slc25a3 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Slc25a3 (solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial phosphate ion transmembrane transport, phosphate ion transmembrane transport, proton transmembrane transport; MF: ph... |
Does Knockout of Abcb7 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,262 | Knockout | Abcb7 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Abcb7 (ATP-binding cassette, sub-family B member 7)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: intracellular iron ion homeostasis, iron ion transmembrane transport, iron-sulfur cluster assembly, iron-sulfur cluster export from the mitochondrion, negative regula... |
Does Knockout of Chek1 in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 578 | Knockout | Chek1 | cell proliferation | Embryonic Stem Cell Line | Gene: Chek1 (checkpoint kinase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage checkpoint signaling, DNA damage response, DNA repair, G2/M transition of mitotic cell cycle, apoptotic process, apoptotic process involved in development, cellular response to me... |
Does Knockout of Tbc1d24 in Microglial Cell Line causally result in response to virus? | 1 | 2,429 | Knockout | Tbc1d24 | response to virus | Microglial Cell Line | Gene: Tbc1d24 (TBC1 domain family, member 24)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: axon development, cellular response to oxidative stress, dendrite development, negative regulation of cellular response to oxidative stress, neuron projection development, positi... |
Does Knockout of Tefm in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,262 | Knockout | Tefm | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Tefm (transcription elongation factor, mitochondrial)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of mitochondrial transcription, regulation of oxidative phosphorylation, transcription elongation by mitochondrial RNA polymerase; MF: nucleic a... |
Does Knockout of Cnot2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 1,130 | Knockout | Cnot2 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Cnot2 (CCR4-NOT transcription complex, subunit 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of intracellular estrogen receptor signaling pathway, negative regulation of transcription by RNA polymerase II, nuclear-transcribed mRNA poly(A) ta... |
Does Knockout of Hspb9 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 688 | Knockout | Hspb9 | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Hspb9 (heat shock protein, alpha-crystallin-related, B9)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: cytoplasm, cytosol, nucleoplasm, nucleus
Pathways:
UniProt: Q9DAM3
Entrez ID: 75482 |
Does Knockout of Kif23 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 1,440 | Knockout | Kif23 | protein/peptide accumulation | Embryonic Cell Line | Gene: Kif23 (kinesin family member 23)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell division, microtubule-based movement, mitotic cytokinesis, mitotic spindle midzone assembly, positive regulation of cytokinesis; MF: ATP binding, ATP hydrolysis activity, microtubu... |
Does Knockout of Bcas1 in Embryonic Fibroblast Cell Line causally result in autophagy? | 1 | 1,044 | Knockout | Bcas1 | autophagy | Embryonic Fibroblast Cell Line | Gene: Bcas1 (brain enriched myelin associated protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: myelination; CC: cytoplasm, cytosol, synapse
Pathways:
UniProt: Q80YN3
Entrez ID: 76960 |
Does Knockout of Ofd1 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,286 | Knockout | Ofd1 | cell proliferation | Mouse kidney carcinoma cell | Gene: Ofd1 (OFD1, centriole and centriolar satellite protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: axoneme assembly, cell projection organization, centriole replication, cilium assembly, embryonic body morphogenesis, epithelial cilium movement involved in deter... |
Does Knockout of Ipo8 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 1,130 | Knockout | Ipo8 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Ipo8 (importin 8)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: intracellular protein transport, nucleocytoplasmic transport, protein import into nucleus, protein transport, transmembrane transport; MF: ATPase-coupled transmembrane transporter activity, small GTPa... |
Does Knockout of Bcl2a1c in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 161 | Knockout | Bcl2a1c | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Bcl2a1c (B cell leukemia/lymphoma 2 related protein A1c)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, extrinsic apoptotic signaling pathway in absence of ligand, intrinsic apoptotic signaling pathway in response to DNA damage, mitochondrial fus... |
Does Knockout of Timm17b in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 2,477 | Knockout | Timm17b | cell proliferation | Embryonic Stem Cell Line | Gene: Timm17b (translocase of inner mitochondrial membrane 17b)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein import into mitochondrial matrix, protein transport; MF: protein transmembrane transporter activity; CC: TIM23 mitochondrial import inner membrane trans... |
Does Knockout of Cd300lb in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,684 | Knockout | Cd300lb | protein/peptide distribution | myoblast cell line | Gene: Cd300lb (CD300 molecule like family member B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to lipopolysaccharide, immune response-activating signaling pathway, immune system process, neutrophil mediated immunity, positive regulation of mast cell... |
Does Knockout of Sbds in Acute Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 684 | Knockout | Sbds | cell proliferation | Acute Myeloid Leukemia Cell Line | Gene: Sbds (SBDS ribosome maturation factor)
Type: protein-coding
Summary: This gene encodes a protein that is necessary for ribosome function and maintaining normal levels of protein synthesis. The encoded protein may function to activate ribosomes for translation, and may be involved in cellular respo... |
Does Knockout of R3hdml in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 83 | Knockout | R3hdml | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: R3hdml (R3H domain containing-like)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: molecular_function, peptidase inhibitor activity; CC: extracellular region, extracellular space
Pathways:
UniProt: A2A5I3
Entrez ID: 100043899 |
Does Knockout of Adgra3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 165 | Knockout | Adgra3 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Adgra3 (adhesion G protein-coupled receptor A3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, cell surface receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity, transmembrane signali... |
Does Knockout of Sh3bgrl in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,681 | Knockout | Sh3bgrl | protein/peptide distribution | myoblast cell line | Gene: Sh3bgrl (SH3-binding domain glutamic acid-rich protein like)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, positive regulation of cytoplasmic translational initiation, proteasome-mediated ubiquitin-dependent protein catabolic process; MF: SH3 d... |
Does Knockout of Ptprz1 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,275 | Knockout | Ptprz1 | cell proliferation | Colonic Cancer Cell Line | Gene: Ptprz1 (protein tyrosine phosphatase receptor type Z, polypeptide 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: axonal fasciculation, axonogenesis, hematopoietic progenitor cell differentiation, learning or memory, negative regulation of cell population prolife... |
Does Knockout of Ndufaf6 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,278 | Knockout | Ndufaf6 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Ndufaf6 (NADH:ubiquinone oxidoreductase complex assembly factor 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial respiratory chain complex I assembly; CC: cytoplasm, membrane, mitochondrial inner membrane, mitochondrion, nucleus
Pathways: Ae... |
Does Knockout of Flii in macrophage causally result in phagocytosis? | 1 | 1,888 | Knockout | Flii | phagocytosis | macrophage | Gene: Flii (flightless I actin binding protein)
Type: protein-coding
Summary: This gene encodes a protein with gelsolin-like repeats and an N-terminal leucine-rich repeat domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect fl... |
Does Knockout of Slc25a21 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,262 | Knockout | Slc25a21 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Slc25a21 (solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: lipid transport, mitochondrial alpha-ketoglutarate transmembrane transport; MF: alpha-ketoglutarate transmembrane transporter acti... |
Does Knockout of Tada2b in Breast Adenocarcinoma Cell Line causally result in tumorigenicity? | 0 | 2,174 | Knockout | Tada2b | tumorigenicity | Breast Adenocarcinoma Cell Line | Gene: Tada2b (transcriptional adaptor 2B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin remodeling, regulation of transcription by RNA polymerase II; MF: chromatin binding, transcription coactivator activity; CC: SAGA-type complex, nucleus
Pathways: D... |
Does Knockout of Dchs1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,280 | Knockout | Dchs1 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Dchs1 (dachsous cadherin related 1)
Type: protein-coding
Summary: Predicted to enable beta-catenin binding activity and cadherin binding activity. Involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; hippo signaling; and mitral valve... |
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