uuid stringlengths 4 8 | template_uuid stringclasses 40 values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 138 627 | execution_results stringlengths 2 1.14M | query_type stringclasses 2 values | sql_category stringclasses 26 values | bio_category stringclasses 14 values |
|---|---|---|---|---|---|---|---|---|
Q10.241 | Q10 | Are there any RP11-1103G16.1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-1103G16.1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-1103G16.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.216 | Q10 | Are there any RP11-196G11.1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-196G11.1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-196G11.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1827 | Q10 | Are there any MIR23A SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within MIR23A that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'MIR23A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1138 | Q10 | Are there any RP4-639F20.1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP4-639F20.1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP4-639F20.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.800 | Q10 | Are there any RP5-874C20.3 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP5-874C20.3 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP5-874C20.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1123 | Q10 | Are there any ASS1P1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ASS1P1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ASS1P1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1583 | Q10 | Are there any MYOZ1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within MYOZ1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'MYOZ1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1672 | Q10 | Are there any LINS1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within LINS1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'LINS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.529 | Q10 | Are there any HAO2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within HAO2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'HAO2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.235 | Q10 | Are there any TBX6 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within TBX6 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'TBX6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.651 | Q10 | Are there any FAM19A1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within FAM19A1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'FAM19A1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1509 | Q10 | Are there any RP11-58C22.1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-58C22.1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-58C22.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.539 | Q10 | Are there any ZNF193 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ZNF193 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'ZNF193' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1753 | Q10 | Are there any POU3F3 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within POU3F3 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'POU3F3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.610 | Q10 | Are there any PTCD1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PTCD1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'PTCD1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1780 | Q10 | Are there any RBBP6 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RBBP6 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RBBP6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1083 | Q10 | Are there any C16orf86 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within C16orf86 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'C16orf86' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1407 | Q10 | Are there any PAFAH1B1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PAFAH1B1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'PAFAH1B1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.62 | Q10 | Are there any RNF40 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RNF40 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RNF40' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1643 | Q10 | Are there any GDAP1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within GDAP1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'GDAP1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.95 | Q10 | Are there any HMGN2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within HMGN2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'HMGN2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.673 | Q10 | Are there any RP11-899L11.1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-899L11.1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-899L11.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.284 | Q10 | Are there any FUT4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within FUT4 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'FUT4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1796 | Q10 | Are there any SNX1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SNX1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SNX1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.364 | Q10 | Are there any RP11-15A1.7 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-15A1.7 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-15A1.7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1468 | Q10 | Are there any KANSL1-AS1 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 9 KANSL1-AS1 SNPs that are significantly associatied with Parkinson's Disease:
• rs199533 (GWAS p-value: 1.09e-18; b-value: -0.2224)
• rs55974014 (GWAS p-value: 8.84e-21; b-value: -0.2571)
• rs2732615 (GWAS p-value: 6.14e-11; b-value: -0.2191)
• rs199456 (GWAS p-value: 3.12e-19; b-value: -0.2268)
• rs12185243 (GWAS p-value: 5.93e-21; b-value: -0.2376)
• rs9468 (GWAS p-value: 5.02e-21; b-value: -0.2371)
• rs2532233 (GWAS p-value: 1.47e-19; b-value: -0.2325)
• rs9896243 (GWAS p-value: 3.17e-18; b-value: -0.2185)
• rs1378358 (GWAS p-value: 8.17e-19; b-value: 0.2241) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'KANSL1-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1476427', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs9468', 'p_GWAS': 5.021668e-21, 'b_GWAS': -0.2371}, {'UUID': 'NDD_SMR_genes_all_update_text_1451663', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs12185243', 'p_GWAS': 5.926176e-21, 'b_GWAS': -0.2376}, {'UUID': 'NDD_SMR_genes_all_update_text_1435918', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs55974014', 'p_GWAS': 8.840428e-21, 'b_GWAS': -0.2571}, {'UUID': 'NDD_SMR_genes_all_update_text_1594924', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs55974014', 'p_GWAS': 8.840428e-21, 'b_GWAS': -0.2571}, {'UUID': 'NDD_SMR_genes_all_update_text_1710350', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs55974014', 'p_GWAS': 8.840428e-21, 'b_GWAS': -0.2571}, {'UUID': 'NDD_SMR_genes_all_update_text_1730065', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs55974014', 'p_GWAS': 8.840428e-21, 'b_GWAS': -0.2571}, {'UUID': 'NDD_SMR_genes_all_update_text_1191172', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs55974014', 'p_GWAS': 8.840428e-21, 'b_GWAS': -0.2571}, {'UUID': 'NDD_SMR_genes_all_update_text_1262225', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs55974014', 'p_GWAS': 8.840428e-21, 'b_GWAS': -0.2571}, {'UUID': 'NDD_SMR_genes_all_update_text_1370546', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs55974014', 'p_GWAS': 8.840428e-21, 'b_GWAS': -0.2571}, {'UUID': 'NDD_SMR_genes_all_update_text_1564785', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs2532233', 'p_GWAS': 1.473642e-19, 'b_GWAS': -0.2325}, {'UUID': 'NDD_SMR_genes_all_update_text_1328934', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199456', 'p_GWAS': 3.118986e-19, 'b_GWAS': -0.2268}, {'UUID': 'NDD_SMR_genes_all_update_text_1679566', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199456', 'p_GWAS': 3.118986e-19, 'b_GWAS': -0.2268}, {'UUID': 'NDD_SMR_genes_all_update_text_1640222', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs1378358', 'p_GWAS': 8.167667999999999e-19, 'b_GWAS': 0.2241}, {'UUID': 'NDD_SMR_genes_all_update_text_1168835', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199533', 'p_GWAS': 1.090724e-18, 'b_GWAS': -0.2224}, {'UUID': 'NDD_SMR_genes_all_update_text_1488140', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199533', 'p_GWAS': 1.090724e-18, 'b_GWAS': -0.2224}, {'UUID': 'NDD_SMR_genes_all_update_text_1281355', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199533', 'p_GWAS': 1.090724e-18, 'b_GWAS': -0.2224}, {'UUID': 'NDD_SMR_genes_all_update_text_1386991', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199533', 'p_GWAS': 1.090724e-18, 'b_GWAS': -0.2224}, {'UUID': 'NDD_SMR_genes_all_update_text_1462895', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199533', 'p_GWAS': 1.090724e-18, 'b_GWAS': -0.2224}, {'UUID': 'NDD_SMR_genes_all_update_text_1603776', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs9896243', 'p_GWAS': 3.170731e-18, 'b_GWAS': -0.2185}, {'UUID': 'NDD_SMR_genes_all_update_text_1242277', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs2732615', 'p_GWAS': 6.139616e-11, 'b_GWAS': -0.2191}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1169 | Q10 | Are there any AC007276.5 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within AC007276.5 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'AC007276.5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.854 | Q10 | Are there any RP11-798G7.8 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 3 RP11-798G7.8 SNPs that are significantly associatied with Parkinson's Disease:
• rs6503443 (GWAS p-value: 1.45e-17; b-value: -0.2201)
• rs62055937 (GWAS p-value: 1.15e-20; b-value: -0.2526)
• rs16940672 (GWAS p-value: 2.45e-20; b-value: -0.2495) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-798G7.8' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1370538', 'Gene': 'RP11-798G7.8', 'topRSID': 'rs62055937', 'p_GWAS': 1.1521279999999999e-20, 'b_GWAS': -0.2526}, {'UUID': 'NDD_SMR_genes_all_update_text_1640215', 'Gene': 'RP11-798G7.8', 'topRSID': 'rs16940672', 'p_GWAS': 2.447966e-20, 'b_GWAS': -0.2495}, {'UUID': 'NDD_SMR_genes_all_update_text_1191165', 'Gene': 'RP11-798G7.8', 'topRSID': 'rs6503443', 'p_GWAS': 1.450783e-17, 'b_GWAS': -0.2201}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1379 | Q10 | Are there any AC017028.7 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within AC017028.7 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'AC017028.7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.113 | Q10 | Are there any CENPO SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CENPO that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CENPO' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.43 | Q10 | Are there any KCNG4 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within KCNG4 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'KCNG4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.128 | Q10 | Are there any RP11-798G7.5 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 RP11-798G7.5 SNPs that are significantly associatied with Alzheimer's Disease:
• rs2532233 (GWAS p-value: 3.69e-08; b-value: -0.0545)
• rs62054805 (GWAS p-value: 4.78e-08; b-value: -0.0535) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-798G7.5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1502440', 'Gene': 'RP11-798G7.5', 'topRSID': 'rs2532233', 'p_GWAS': 3.690625e-08, 'b_GWAS': -0.0545}, {'UUID': 'NDD_SMR_genes_all_update_text_1610856', 'Gene': 'RP11-798G7.5', 'topRSID': 'rs62054805', 'p_GWAS': 4.783287e-08, 'b_GWAS': -0.0535}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.207 | Q10 | Are there any FBXO3 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within FBXO3 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'FBXO3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.53 | Q10 | Are there any HMCN2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within HMCN2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'HMCN2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.551 | Q10 | Are there any SLC16A12 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within SLC16A12 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'SLC16A12' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.71 | Q10 | Are there any CNPY4 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 CNPY4 SNPs that are significantly associatied with Alzheimer's Disease:
• rs11767968 (GWAS p-value: 1.23e-09; b-value: 0.0559)
• rs11505847 (GWAS p-value: 6.58e-10; b-value: -0.0562) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CNPY4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1198845', 'Gene': 'CNPY4', 'topRSID': 'rs11505847', 'p_GWAS': 6.58192e-10, 'b_GWAS': -0.0562}, {'UUID': 'NDD_SMR_genes_all_update_text_1105969', 'Gene': 'CNPY4', 'topRSID': 'rs11767968', 'p_GWAS': 1.231506e-09, 'b_GWAS': 0.0559}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1816 | Q10 | Are there any PRKCA SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PRKCA that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'PRKCA' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1745 | Q10 | Are there any TMED3 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within TMED3 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'TMED3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.186 | Q10 | Are there any OOSP4B SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within OOSP4B that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'OOSP4B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.140 | Q10 | Are there any CLN5 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CLN5 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'CLN5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.907 | Q10 | Are there any WNT3 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within WNT3 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'WNT3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.803 | Q10 | Are there any BCHE SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within BCHE that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'BCHE' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.135 | Q10 | Are there any LRRC37A4P SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there is at least 17 LRRC37A4P SNP that are significantly associatied with Parkinson's Disease:
• rs58879558 (GWAS p-value: 1.54e-21; b-value: -0.2383)
• rs112560196 (GWAS p-value: 3.63e-21; b-value: -0.2559)
• rs570200944 (GWAS p-value: 5.14e-21; b-value: -0.2408)
• rs112411928 (GWAS p-value: 5.29e-21; b-value: -0.2379)
• rs62060768 (GWAS p-value: 5.50e-21; b-value: -0.2378)
• rs62062283 (GWAS p-value: 5.71e-21; b-value: -0.2377)
• rs112746008 (GWAS p-value: 5.71e-21; b-value: -0.2377)
• rs112155389 (GWAS p-value: 5.77e-21; b-value: -0.2527)
• rs2942166 (GWAS p-value: 1.25e-20; b-value: -0.2561)
• rs62057151 (GWAS p-value: 1.36e-20; b-value: -0.2484) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'LRRC37A4P' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1451658', 'Gene': 'LRRC37A4P', 'topRSID': 'rs58879558', 'p_GWAS': 1.542818e-21, 'b_GWAS': -0.2383}, {'UUID': 'NDD_SMR_genes_all_update_text_1564777', 'Gene': 'LRRC37A4P', 'topRSID': 'rs112560196', 'p_GWAS': 3.62933e-21, 'b_GWAS': -0.2559}, {'UUID': 'NDD_SMR_genes_all_update_text_1242262', 'Gene': 'LRRC37A4P', 'topRSID': 'rs570200944', 'p_GWAS': 5.141538e-21, 'b_GWAS': -0.2408}, {'UUID': 'NDD_SMR_genes_all_update_text_1603772', 'Gene': 'LRRC37A4P', 'topRSID': 'rs112411928', 'p_GWAS': 5.294745e-21, 'b_GWAS': -0.2379}, {'UUID': 'NDD_SMR_genes_all_update_text_1386986', 'Gene': 'LRRC37A4P', 'topRSID': 'rs62060768', 'p_GWAS': 5.497454e-21, 'b_GWAS': -0.2378}, {'UUID': 'NDD_SMR_genes_all_update_text_1488135', 'Gene': 'LRRC37A4P', 'topRSID': 'rs62060768', 'p_GWAS': 5.497454e-21, 'b_GWAS': -0.2378}, {'UUID': 'NDD_SMR_genes_all_update_text_1594919', 'Gene': 'LRRC37A4P', 'topRSID': 'rs62062283', 'p_GWAS': 5.707835e-21, 'b_GWAS': -0.2377}, {'UUID': 'NDD_SMR_genes_all_update_text_1730058', 'Gene': 'LRRC37A4P', 'topRSID': 'rs62062283', 'p_GWAS': 5.707835e-21, 'b_GWAS': -0.2377}, {'UUID': 'NDD_SMR_genes_all_update_text_1640214', 'Gene': 'LRRC37A4P', 'topRSID': 'rs112746008', 'p_GWAS': 5.707835e-21, 'b_GWAS': -0.2377}, {'UUID': 'NDD_SMR_genes_all_update_text_1462889', 'Gene': 'LRRC37A4P', 'topRSID': 'rs112155389', 'p_GWAS': 5.773536e-21, 'b_GWAS': -0.2527}, {'UUID': 'NDD_SMR_genes_all_update_text_1476420', 'Gene': 'LRRC37A4P', 'topRSID': 'rs2942166', 'p_GWAS': 1.245913e-20, 'b_GWAS': -0.2561}, {'UUID': 'NDD_SMR_genes_all_update_text_1168831', 'Gene': 'LRRC37A4P', 'topRSID': 'rs62057151', 'p_GWAS': 1.3606219999999998e-20, 'b_GWAS': -0.2484}, {'UUID': 'NDD_SMR_genes_all_update_text_1191164', 'Gene': 'LRRC37A4P', 'topRSID': 'rs62055496', 'p_GWAS': 1.439249e-20, 'b_GWAS': -0.2501}, {'UUID': 'NDD_SMR_genes_all_update_text_1370537', 'Gene': 'LRRC37A4P', 'topRSID': 'rs757055', 'p_GWAS': 2.131192e-20, 'b_GWAS': -0.2499}, {'UUID': 'NDD_SMR_genes_all_update_text_1262219', 'Gene': 'LRRC37A4P', 'topRSID': 'rs62063271', 'p_GWAS': 2.447966e-20, 'b_GWAS': -0.2495}, {'UUID': 'NDD_SMR_genes_all_update_text_1281349', 'Gene': 'LRRC37A4P', 'topRSID': 'rs62062813', 'p_GWAS': 6.23246e-20, 'b_GWAS': -0.2477}, {'UUID': 'NDD_SMR_genes_all_update_text_1710342', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1991556', 'p_GWAS': 1.3587429999999998e-19, 'b_GWAS': -0.2282}, {'UUID': 'NDD_SMR_genes_all_update_text_1435914', 'Gene': 'LRRC37A4P', 'topRSID': 'rs62065450', 'p_GWAS': 3.844278e-16, 'b_GWAS': -0.2272}, {'UUID': 'NDD_SMR_genes_all_update_text_1328924', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1724390', 'p_GWAS': 5.141398e-16, 'b_GWAS': -0.21}, {'UUID': 'NDD_SMR_genes_all_update_text_1679559', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1724390', 'p_GWAS': 5.141398e-16, 'b_GWAS': -0.21}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.83 | Q10 | Are there any CELSR1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CELSR1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CELSR1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1541 | Q10 | Are there any CFAP157 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CFAP157 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CFAP157' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.547 | Q10 | Are there any LYRM9 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within LYRM9 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'LYRM9' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1596 | Q10 | Are there any CTD-2619J13.8 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CTD-2619J13.8 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CTD-2619J13.8' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.992 | Q10 | Are there any HYI SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within HYI that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'HYI' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.168 | Q10 | Are there any BCL3 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 4 BCL3 SNPs that are significantly associatied with Alzheimer's Disease:
• rs17658713 (GWAS p-value: 3.69e-14; b-value: 0.0795)
• rs62117204 (GWAS p-value: 1.59e-30; b-value: 0.2159)
• rs8100197 (GWAS p-value: 9.06e-21; b-value: -0.0944)
• rs1531517 (GWAS p-value: 1.66e-29; b-value: -0.2098) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'BCL3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122454', 'Gene': 'BCL3', 'topRSID': 'rs62117204', 'p_GWAS': 1.5868369999999998e-30, 'b_GWAS': 0.2159}, {'UUID': 'NDD_SMR_genes_all_update_text_1503904', 'Gene': 'BCL3', 'topRSID': 'rs1531517', 'p_GWAS': 1.6555340000000004e-29, 'b_GWAS': -0.2098}, {'UUID': 'NDD_SMR_genes_all_update_text_637414', 'Gene': 'BCL3', 'topRSID': 'rs8100197', 'p_GWAS': 9.05664e-21, 'b_GWAS': -0.0944}, {'UUID': 'NDD_SMR_genes_all_update_text_122453', 'Gene': 'BCL3', 'topRSID': 'rs17658713', 'p_GWAS': 3.69142e-14, 'b_GWAS': 0.0795}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.251 | Q10 | Are there any BMP2K SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within BMP2K that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'BMP2K' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.452 | Q10 | Are there any PMS2P1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 PMS2P1 SNPs that are significantly associatied with Alzheimer's Disease:
• rs7384878 (GWAS p-value: 3.10e-18; b-value: 0.0775)
• rs2405442 (GWAS p-value: 9.52e-18; b-value: -0.0755) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'PMS2P1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_74053', 'Gene': 'PMS2P1', 'topRSID': 'rs7384878', 'p_GWAS': 3.096513e-18, 'b_GWAS': 0.0775}, {'UUID': 'NDD_SMR_genes_all_update_text_585989', 'Gene': 'PMS2P1', 'topRSID': 'rs2405442', 'p_GWAS': 9.524878000000001e-18, 'b_GWAS': -0.0755}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1148 | Q10 | Are there any PLCH1-AS1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within PLCH1-AS1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'PLCH1-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.865 | Q10 | Are there any DAPK2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within DAPK2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'DAPK2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1233 | Q10 | Are there any SERPINA4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SERPINA4 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'SERPINA4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.100 | Q10 | Are there any PSG2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within PSG2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'PSG2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1974 | Q10 | Are there any LHFPL4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within LHFPL4 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'LHFPL4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.744 | Q10 | Are there any DND1P1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 DND1P1 SNPs that are significantly associatied with Alzheimer's Disease:
• rs199447 (GWAS p-value: 6.63e-09; b-value: -0.058)
• rs55974014 (GWAS p-value: 1.54e-08; b-value: -0.056) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'DND1P1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_591167', 'Gene': 'DND1P1', 'topRSID': 'rs199447', 'p_GWAS': 6.631492e-09, 'b_GWAS': -0.058}, {'UUID': 'NDD_SMR_genes_all_update_text_1343149', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1466642', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1480155', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1291754', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1652495', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1690041', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1454352', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1717373', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1446733', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1268111', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1598266', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1157197', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1584307', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1378566', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1247080', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1252 | Q10 | Are there any RP11-1281K21.1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-1281K21.1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-1281K21.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.105 | Q10 | Are there any ERCC8 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ERCC8 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ERCC8' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.440 | Q10 | Are there any novel_or_none SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within novel_or_none that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'novel_or_none' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.77 | Q10 | Are there any ENPP7P1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within ENPP7P1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'ENPP7P1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1793 | Q10 | Are there any RP11-665C16.6 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-665C16.6 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-665C16.6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1462 | Q10 | Are there any MIR635 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within MIR635 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'MIR635' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.926 | Q10 | Are there any VPS11 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within VPS11 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'VPS11' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1712 | Q10 | Are there any CTC-264K15.6 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CTC-264K15.6 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CTC-264K15.6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1671 | Q10 | Are there any BLNK SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within BLNK that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'BLNK' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1621 | Q10 | Are there any LRRC16A SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within LRRC16A that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'LRRC16A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.769 | Q10 | Are there any C22orf33 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within C22orf33 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'C22orf33' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.998 | Q10 | Are there any RP11-354E11.2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-354E11.2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP11-354E11.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.394 | Q10 | Are there any LEMD2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within LEMD2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'LEMD2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.238 | Q10 | Are there any RP11-103B5.2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-103B5.2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-103B5.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1508 | Q10 | Are there any KANSL1L SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within KANSL1L that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'KANSL1L' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.270 | Q10 | Are there any C1orf61 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within C1orf61 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'C1orf61' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1187 | Q10 | Are there any MAPT-AS1 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there is at least 16 MAPT-AS1 SNP that are significantly associatied with Parkinson's Disease:
• rs3785884 (GWAS p-value: 2.54e-21; b-value: -0.237)
• rs112073200 (GWAS p-value: 4.33e-21; b-value: -0.2554)
• rs112411928 (GWAS p-value: 5.29e-21; b-value: -0.2379)
• rs62063845 (GWAS p-value: 7.42e-21; b-value: -0.237)
• rs113790915 (GWAS p-value: 9.79e-21; b-value: -0.2512)
• rs56189701 (GWAS p-value: 9.91e-21; b-value: -0.2521)
• rs62056790 (GWAS p-value: 1.09e-20; b-value: -0.2509)
• rs62055937 (GWAS p-value: 1.15e-20; b-value: -0.2526)
• rs78026984 (GWAS p-value: 1.49e-20; b-value: -0.25)
• rs10445363 (GWAS p-value: 2.13e-20; b-value: -0.2499) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'MAPT-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491099', 'Gene': 'MAPT-AS1', 'topRSID': 'rs3785884', 'p_GWAS': 2.542831e-21, 'b_GWAS': -0.237}, {'UUID': 'NDD_SMR_genes_all_update_text_948873', 'Gene': 'MAPT-AS1', 'topRSID': 'rs112073200', 'p_GWAS': 4.3276019999999996e-21, 'b_GWAS': -0.2554}, {'UUID': 'NDD_SMR_genes_all_update_text_1281353', 'Gene': 'MAPT-AS1', 'topRSID': 'rs112411928', 'p_GWAS': 5.294745e-21, 'b_GWAS': -0.2379}, {'UUID': 'NDD_SMR_genes_all_update_text_491098', 'Gene': 'MAPT-AS1', 'topRSID': 'rs62063845', 'p_GWAS': 7.420828e-21, 'b_GWAS': -0.237}, {'UUID': 'NDD_SMR_genes_all_update_text_948874', 'Gene': 'MAPT-AS1', 'topRSID': 'rs113790915', 'p_GWAS': 9.790249e-21, 'b_GWAS': -0.2512}, {'UUID': 'NDD_SMR_genes_all_update_text_491097', 'Gene': 'MAPT-AS1', 'topRSID': 'rs56189701', 'p_GWAS': 9.906762e-21, 'b_GWAS': -0.2521}, {'UUID': 'NDD_SMR_genes_all_update_text_948869', 'Gene': 'MAPT-AS1', 'topRSID': 'rs62056790', 'p_GWAS': 1.087687e-20, 'b_GWAS': -0.2509}, {'UUID': 'NDD_SMR_genes_all_update_text_1730063', 'Gene': 'MAPT-AS1', 'topRSID': 'rs62055937', 'p_GWAS': 1.1521279999999999e-20, 'b_GWAS': -0.2526}, {'UUID': 'NDD_SMR_genes_all_update_text_948871', 'Gene': 'MAPT-AS1', 'topRSID': 'rs78026984', 'p_GWAS': 1.490436e-20, 'b_GWAS': -0.25}, {'UUID': 'NDD_SMR_genes_all_update_text_948872', 'Gene': 'MAPT-AS1', 'topRSID': 'rs10445363', 'p_GWAS': 2.131192e-20, 'b_GWAS': -0.2499}, {'UUID': 'NDD_SMR_genes_all_update_text_491096', 'Gene': 'MAPT-AS1', 'topRSID': 'rs56280951', 'p_GWAS': 3.579498e-20, 'b_GWAS': -0.2346}, {'UUID': 'NDD_SMR_genes_all_update_text_1462893', 'Gene': 'MAPT-AS1', 'topRSID': 'rs242559', 'p_GWAS': 9.821437e-20, 'b_GWAS': 0.24}, {'UUID': 'NDD_SMR_genes_all_update_text_948870', 'Gene': 'MAPT-AS1', 'topRSID': 'rs169201', 'p_GWAS': 4.460973e-19, 'b_GWAS': -0.2258}, {'UUID': 'NDD_SMR_genes_all_update_text_1370544', 'Gene': 'MAPT-AS1', 'topRSID': 'rs1879585', 'p_GWAS': 2.375267e-16, 'b_GWAS': -0.228}, {'UUID': 'NDD_SMR_genes_all_update_text_1242274', 'Gene': 'MAPT-AS1', 'topRSID': 'rs575074983', 'p_GWAS': 4.979874e-12, 'b_GWAS': -0.2134}, {'UUID': 'NDD_SMR_genes_all_update_text_491091', 'Gene': 'MAPT-AS1', 'topRSID': 'rs242937', 'p_GWAS': 3.041402e-09, 'b_GWAS': -0.1091}, {'UUID': 'NDD_SMR_genes_all_update_text_491092', 'Gene': 'MAPT-AS1', 'topRSID': 'rs242937', 'p_GWAS': 3.041402e-09, 'b_GWAS': -0.1091}, {'UUID': 'NDD_SMR_genes_all_update_text_491094', 'Gene': 'MAPT-AS1', 'topRSID': 'rs242937', 'p_GWAS': 3.041402e-09, 'b_GWAS': -0.1091}, {'UUID': 'NDD_SMR_genes_all_update_text_491095', 'Gene': 'MAPT-AS1', 'topRSID': 'rs242937', 'p_GWAS': 3.041402e-09, 'b_GWAS': -0.1091}, {'UUID': 'NDD_SMR_genes_all_update_text_491093', 'Gene': 'MAPT-AS1', 'topRSID': 'rs242937', 'p_GWAS': 3.041402e-09, 'b_GWAS': -0.1091}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.120 | Q10 | Are there any RP11-4E23.2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-4E23.2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP11-4E23.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1607 | Q10 | Are there any FXYD7 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within FXYD7 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'FXYD7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.680 | Q10 | Are there any XXYLT1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within XXYLT1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'XXYLT1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.252 | Q10 | Are there any RGS12 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RGS12 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RGS12' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1958 | Q10 | Are there any LRRC74B SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within LRRC74B that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'LRRC74B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1995 | Q10 | Are there any SPCS2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SPCS2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SPCS2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.97 | Q10 | Are there any DMRTA1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within DMRTA1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'DMRTA1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.34 | Q10 | Are there any RP4-800J21.3 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP4-800J21.3 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP4-800J21.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1465 | Q10 | Are there any C19orf18 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within C19orf18 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'C19orf18' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1668 | Q10 | Are there any NABP2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within NABP2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'NABP2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.454 | Q10 | Are there any SLC25A16 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SLC25A16 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'SLC25A16' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.723 | Q10 | Are there any PSMC3 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 PSMC3 SNPs that are significantly associatied with Alzheimer's Disease:
• rs7104036 (GWAS p-value: 4.39e-11; b-value: -0.0547)
• rs12292911 (GWAS p-value: 3.73e-11; b-value: 0.0549) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'PSMC3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_608490', 'Gene': 'PSMC3', 'topRSID': 'rs12292911', 'p_GWAS': 3.729159e-11, 'b_GWAS': 0.0549}, {'UUID': 'NDD_SMR_genes_all_update_text_91158', 'Gene': 'PSMC3', 'topRSID': 'rs7104036', 'p_GWAS': 4.387571e-11, 'b_GWAS': -0.0547}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1261 | Q10 | Are there any BCAR3 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within BCAR3 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'BCAR3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1598 | Q10 | Are there any OR14A16 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within OR14A16 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'OR14A16' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1 | Q10 | Are there any ALS2CL SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within ALS2CL that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'ALS2CL' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1377 | Q10 | Are there any SRA1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SRA1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SRA1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1110 | Q10 | Are there any C12orf43 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within C12orf43 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'C12orf43' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1117 | Q10 | Are there any RP11-259G18.1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are at least 5 RP11-259G18.1 SNPs that are significantly associatied with Progressive supranuclear palsy:
• rs1981997 (GWAS p-value: 1.79e-51; b-value: 1.715)
• rs1635291 (GWAS p-value: 5.42e-51; b-value: -1.421)
• rs12373139 (GWAS p-value: 4.65e-51; b-value: 1.688)
• rs169201 (GWAS p-value: 8.55e-46; b-value: 1.588)
• rs11012 (GWAS p-value: 2.11e-42; b-value: 1.608) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP11-259G18.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1596825', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1264985', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1375932', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1604716', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1194220', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1732398', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1170876', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1714159', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1464421', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1336294', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs12373139', 'p_GWAS': 4.650637e-51, 'b_GWAS': 1.6879}, {'UUID': 'NDD_SMR_genes_all_update_text_1283706', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs1635291', 'p_GWAS': 5.423847e-51, 'b_GWAS': -1.4209}, {'UUID': 'NDD_SMR_genes_all_update_text_1579425', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs169201', 'p_GWAS': 8.550985e-46, 'b_GWAS': 1.5881}, {'UUID': 'NDD_SMR_genes_all_update_text_1489541', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs169201', 'p_GWAS': 8.550985e-46, 'b_GWAS': 1.5881}, {'UUID': 'NDD_SMR_genes_all_update_text_1646047', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs11012', 'p_GWAS': 2.10769e-42, 'b_GWAS': 1.6076}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1591 | Q10 | Are there any RNF40 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there is at least 1 RNF40 SNP that are significantly associatied with Parkinson's Disease:
• rs7200879 (GWAS p-value: 2.09e-09; b-value: -0.124) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RNF40' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1729880', 'Gene': 'RNF40', 'topRSID': 'rs7200879', 'p_GWAS': 2.094052e-09, 'b_GWAS': -0.124}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.85 | Q10 | Are there any CFAP221 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CFAP221 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'CFAP221' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1294 | Q10 | Are there any SRCAP SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SRCAP that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SRCAP' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.683 | Q10 | Are there any LA16c-381G6.1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within LA16c-381G6.1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'LA16c-381G6.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1677 | Q10 | Are there any C2CD5 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within C2CD5 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'C2CD5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1055 | Q10 | Are there any AURKA SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AURKA that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'AURKA' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.777 | Q10 | Are there any NGLY1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within NGLY1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'NGLY1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1289 | Q10 | Are there any ITGA7 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ITGA7 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ITGA7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
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