uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
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Q59.662 | Q59 | What is the genetic target of the small molecule drug Memantine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 7 genetic targets of the small molecule drug Memantine Hydrochloride: GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. Memantine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%memantine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%memanti... | [{'UUID': 'DrugGeneTargets_v2_4606', 'drugName': 'Memantine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRIN1 (ENSG00000176884), GRIN2A (ENSG00000183454), GRIN2B (ENSG00000273079), GRIN2D (ENSG00000105464), GRIN3B (ENSG00000116032), GRIN2C (ENSG00000161509), GRIN3A (ENSG0000019878... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.944 | Q59 | What is the genetic target of the small molecule drug Atorvastatin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Atorvastatin is HMGCR. Atorvastatin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%atorvastatin%" OR LOWER(tradeNames_string) LIKE "%atorvastatin%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4251', 'drugName': 'Atorvastatin Calcium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HMGCR (ENSG00000113161)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4983', 'drugName': 'Atorvastatin', 'drugMol... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.829 | Q59 | What is the genetic target of the small molecule drug Ponatinib, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Ponatinib: ABL1 and BCR. Ponatinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ponatinib%" OR LOWER(tradeNames_string) LIKE "%ponatinib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2277', 'drugName': 'Ponatinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ABL1 (ENSG00000097007), BCR (ENSG00000186716)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6150', 'drugName': 'Ponatinib Hy... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.873 | Q59 | What is the genetic target of the small molecule drug Cnv2197944, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Cnv2197944 is CACNA1B. Cnv2197944 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cnv2197944%" OR LOWER(tradeNames_string) LIKE "%cnv2197944%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3408', 'drugName': 'Cnv2197944', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1B (ENSG00000148408)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.47 | Q59 | What is the genetic target of the small molecule drug Benoxaprofen, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Benoxaprofen is ALOX12. Benoxaprofen reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%benoxaprofen%" OR LOWER(tradeNames_string) LIKE "%benoxaprofen%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5509', 'drugName': 'Benoxaprofen', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ALOX12 (ENSG00000108839)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1388 | Q59 | What is the genetic target of the small molecule drug Olmesartan Medoxomil, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Olmesartan Medoxomil is AGTR1. Olmesartan Medoxomil reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%olmesartan medoxomil%" OR LOWER(tradeNames_string) LIKE "%olmesartan... | [{'UUID': 'DrugGeneTargets_v2_2021', 'drugName': 'Olmesartan Medoxomil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AGTR1 (ENSG00000144891)', 'yearOfFirstApproval': 2002, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4635', 'drugName': 'Olmesartan', 'drugMolec... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1709 | Q59 | What is the genetic target of the small molecule drug Serdexmethylphenidate Chloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Serdexmethylphenidate Chloride: SLC6A3 and SLC6A2. Serdexmethylphenidate Chloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%serdexmethylphenidate chloride%" OR LOWER(tradeNames_string) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4160', 'drugName': 'Serdexmethylphenidate Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4161',... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1000 | Q59 | What is the genetic target of the small molecule drug Digoxin, and what is its status in clinical trials and FDA approval? | There are 8 genetic targets of the small molecule drug Digoxin: ATP1A1, ATP1B2, ATP1B1, ATP1A2, ATP1B3, ATP1A3, ATP1A4, and FXYD2. Digoxin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%digoxin%" OR LOWER(tradeNames_string) LIKE "%digoxin%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_2499', 'drugName': 'Digoxin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP1A1 (ENSG00000163399), ATP1B2 (ENSG00000129244), ATP1B1 (ENSG00000143153), ATP1A2 (ENSG00000018625), ATP1B3 (ENSG00000069849), ATP1A3 (ENSG00000105409), ATP1A4 (ENSG00000132681), FXYD2 (ENSG... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.883 | Q59 | What is the genetic target of the small molecule drug Repinotan, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Repinotan is HTR1A. Repinotan reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%repinotan%" OR LOWER(tradeNames_string) LIKE "%repinotan%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4469', 'drugName': 'Repinotan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1A (ENSG00000178394)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.780 | Q59 | What is the genetic target of the small molecule drug Methyldopa, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Methyldopa: ADRA2A, ADRA2C, and ADRA2B. Methyldopa reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methyldopa%" OR LOWER(tradeNames_string) LIKE "%methyldopa%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6296', 'drugName': 'Methyldopa', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 1962, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1229 | Q59 | What is the genetic target of the small molecule drug Sotagliflozin, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Sotagliflozin: SLC5A1 and SLC5A2. Sotagliflozin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sotagliflozin%" OR LOWER(tradeNames_string) LIKE "%sotagliflozin%" O... | [{'UUID': 'DrugGeneTargets_v2_4365', 'drugName': 'Sotagliflozin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC5A1 (ENSG00000100170), SLC5A2 (ENSG00000140675)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4366', 'drugName': 'Sotagl... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.2000 | Q59 | What is the genetic target of the protein drug Triptorelin Pamoate, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Triptorelin Pamoate is GNRHR. Triptorelin Pamoate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%triptorelin pamoate%" OR LOWER(tradeNames_string) LIKE "%triptorelin... | [{'UUID': 'DrugGeneTargets_v2_4710', 'drugName': 'Triptorelin Pamoate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.5 | Q59 | What is the genetic target of the small molecule drug Desogestrel, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Desogestrel is PGR. Desogestrel reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%desogestrel%" OR LOWER(tradeNames_string) LIKE "%desogestrel%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2631', 'drugName': 'Desogestrel', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'yearOfFirstApproval': 1992, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1012 | Q59 | What is the genetic target of the small molecule drug Metipranolol, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Metipranolol: ADRB2 and ADRB1. Metipranolol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%metipranolol%" OR LOWER(tradeNames_string) LIKE "%metipranolol%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2263', 'drugName': 'Metipranolol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252), ADRB1 (ENSG00000043591)', 'yearOfFirstApproval': 1989, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2262', 'drugName': 'Metipr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1724 | Q59 | What is the genetic target of the small molecule drug Ave8134, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ave8134 is PPARA. Ave8134 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ave8134%" OR LOWER(tradeNames_string) LIKE "%ave8134%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_2837', 'drugName': 'Ave8134', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARA (ENSG00000186951)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.266 | Q59 | What is the genetic target of the small molecule drug Esuberaprost, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Esuberaprost is PTGIR. Esuberaprost reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%esuberaprost%" OR LOWER(tradeNames_string) LIKE "%esuberaprost%" OR ... | [{'UUID': 'DrugGeneTargets_v2_6323', 'drugName': 'Esuberaprost', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGIR (ENSG00000160013)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1570 | Q59 | What is the genetic target of the small molecule drug Clevidipine, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Clevidipine: CACNA1C, CACNA1S, CACNA1D, and CACNA1F. Clevidipine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%clevidipine%" OR LOWER(tradeNames_string) LIKE "%clevidipine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_250', 'drugName': 'Clevidipine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1832 | Q59 | What is the genetic target of the small molecule drug Omipalisib, and what is its status in clinical trials and FDA approval? | There are 9 genetic targets of the small molecule drug Omipalisib: MTOR, PIK3R1, PIK3CB, PIK3CG, PIK3CA, PIK3R2, PIK3CD, PIK3R5, and PIK3R3. Omipalisib reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%omipalisib%" OR LOWER(tradeNames_string) LIKE "%omipalisib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5350', 'drugName': 'Omipalisib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MTOR (ENSG00000198793), PIK3R1 (ENSG00000145675), PIK3CB (ENSG00000051382), PIK3CG (ENSG00000105851), PIK3CA (ENSG00000121879), PIK3R2 (ENSG00000105647), PIK3CD (ENSG00000171608), PIK3R5 (EN... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.449 | Q59 | What is the genetic target of the protein drug Atosiban, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Atosiban is OXTR. Atosiban reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%atosiban%" OR LOWER(tradeNames_string) LIKE "%atosiban%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_4904', 'drugName': 'Atosiban', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'OXTR (ENSG00000180914)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1011 | Q59 | What is the genetic target of the small molecule drug Sonidegib Phosphate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Sonidegib Phosphate is SMO. Sonidegib Phosphate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sonidegib phosphate%" OR LOWER(tradeNames_string) LIKE "%sonidegib p... | [{'UUID': 'DrugGeneTargets_v2_3933', 'drugName': 'Sonidegib Phosphate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SMO (ENSG00000128602)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1086 | Q59 | What is the genetic target of the small molecule drug Mycophenolate Mofetil, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Mycophenolate Mofetil: IMPDH1 and IMPDH2. Mycophenolate Mofetil reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mycophenolate mofetil%" OR LOWER(tradeNames_string) LIKE "%mycopheno... | [{'UUID': 'DrugGeneTargets_v2_290', 'drugName': 'Mycophenolate Mofetil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'IMPDH1 (ENSG00000106348), IMPDH2 (ENSG00000178035)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1227', 'drugName... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.844 | Q59 | What is the genetic target of the small molecule drug Pargyline Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Pargyline Hydrochloride: MAOA and MAOB. Pargyline Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pargyline hydrochloride%" OR LOWER(tradeNames_string) LIKE "%pargyli... | [{'UUID': 'DrugGeneTargets_v2_1196', 'drugName': 'Pargyline Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAOA (ENSG00000189221), MAOB (ENSG00000069535)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1792 | Q59 | What is the genetic target of the small molecule drug Diclofenac Epolamine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Diclofenac Epolamine: PTGS2 and PTGS1. Diclofenac Epolamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%diclofenac epolamine%" OR LOWER(tradeNames_string) LIKE "%diclofenac... | [{'UUID': 'DrugGeneTargets_v2_3087', 'drugName': 'Diclofenac Epolamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 2007, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.308 | Q59 | What is the genetic target of the small molecule drug Alogliptin Benzoate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Alogliptin Benzoate is DPP4. Alogliptin Benzoate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alogliptin benzoate%" OR LOWER(tradeNames_string) LIKE "%alogliptin ... | [{'UUID': 'DrugGeneTargets_v2_2469', 'drugName': 'Alogliptin Benzoate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DPP4 (ENSG00000197635)', 'yearOfFirstApproval': 2013, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1380 | Q59 | What is the genetic target of the small molecule drug Gsk-2269557, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Gsk-2269557 is PIK3CD. Gsk-2269557 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%gsk-2269557%" OR LOWER(tradeNames_string) LIKE "%gsk-2269557%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2005', 'drugName': 'Gsk-2269557', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PIK3CD (ENSG00000171608)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_2646', 'drugName': 'Nemiralisib', 'drugMolecularType'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1558 | Q59 | What is the genetic target of the small molecule drug Paramethadione, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Paramethadione: CACNA1H, CACNA1G, and CACNA1I. Paramethadione reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%paramethadione%" OR LOWER(tradeNames_string) LIKE "%paramethadione%"... | [{'UUID': 'DrugGeneTargets_v2_4508', 'drugName': 'Paramethadione', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1H (ENSG00000196557), CACNA1G (ENSG00000006283), CACNA1I (ENSG00000100346)', 'yearOfFirstApproval': 1949, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.317 | Q59 | What is the genetic target of the small molecule drug Bisantrene, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bisantrene is FTO. Bisantrene reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bisantrene%" OR LOWER(tradeNames_string) LIKE "%bisantrene%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1486', 'drugName': 'Bisantrene', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FTO (ENSG00000140718)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.152 | Q59 | What is the genetic target of the small molecule drug Tapentadol Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Tapentadol Hydrochloride: SLC6A2 and OPRM1. Tapentadol Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tapentadol hydrochloride%" OR LOWER(tradeNames_string) LIKE "%tapent... | [{'UUID': 'DrugGeneTargets_v2_6372', 'drugName': 'Tapentadol Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546), OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6373', 'drugN... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1158 | Q59 | What is the genetic target of the small molecule drug Infigratinib Phosphate, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Infigratinib Phosphate: FGFR3, FGFR1, FGFR4, and FGFR2. Infigratinib Phosphate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%infigratinib phosphate%" OR LOWER(tradeNames_string) LIKE "%infigrat... | [{'UUID': 'DrugGeneTargets_v2_3003', 'drugName': 'Infigratinib Phosphate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FGFR3 (ENSG00000068078), FGFR1 (ENSG00000077782), FGFR4 (ENSG00000160867), FGFR2 (ENSG00000066468)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': Tr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1223 | Q59 | What is the genetic target of the small molecule drug Methixene Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Methixene Hydrochloride: CHRM1 and HTR2C. Methixene Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methixene hydrochloride%" OR LOWER(tradeNames_string) LIKE "%methixe... | [{'UUID': 'DrugGeneTargets_v2_348', 'drugName': 'Methixene Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539), HTR2C (ENSG00000147246)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_349', 'drugName'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.580 | Q59 | What is the genetic target of the small molecule drug Piritrexim, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Piritrexim is DHFR. Piritrexim reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%piritrexim%" OR LOWER(tradeNames_string) LIKE "%piritrexim%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_734', 'drugName': 'Piritrexim', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DHFR (ENSG00000228716)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.51 | Q59 | What is the genetic target of the antibody drug Ozoralizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Ozoralizumab is TNF. Ozoralizumab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ozoralizumab%" OR LOWER(tradeNames_string) LIKE "%ozoralizumab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5268', 'drugName': 'Ozoralizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TNF (ENSG00000232810)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1553 | Q59 | What is the genetic target of the small molecule drug Naproxen, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Naproxen: PTGS2 and PTGS1. Naproxen reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%naproxen%" OR LOWER(tradeNames_string) LIKE "%naproxen%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_4517', 'drugName': 'Naproxen', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1976, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5291', 'drugName': 'Naproxen S... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.733 | Q59 | What is the genetic target of the small molecule drug Ribavirin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ribavirin is IMPDH1. Ribavirin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ribavirin%" OR LOWER(tradeNames_string) LIKE "%ribavirin%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3809', 'drugName': 'Ribavirin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'IMPDH1 (ENSG00000106348)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3810', 'drugName': 'Ribavirin', 'drugMolecularType': ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.840 | Q59 | What is the genetic target of the small molecule drug Metipranolol Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Metipranolol Hydrochloride: ADRB2 and ADRB1. Metipranolol Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%metipranolol hydrochloride%" OR LOWER(tradeNames_string) LIKE "%meti... | [{'UUID': 'DrugGeneTargets_v2_4267', 'drugName': 'Metipranolol Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252), ADRB1 (ENSG00000043591)', 'yearOfFirstApproval': 1989, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4268', 'drug... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1392 | Q59 | What is the genetic target of the antibody drug Cedelizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Cedelizumab is CD4. Cedelizumab reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cedelizumab%" OR LOWER(tradeNames_string) LIKE "%cedelizumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2501', 'drugName': 'Cedelizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD4 (ENSG00000010610)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1125 | Q59 | What is the genetic target of the small molecule drug Seltorexant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Seltorexant is HCRTR2. Seltorexant reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%seltorexant%" OR LOWER(tradeNames_string) LIKE "%seltorexant%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4820', 'drugName': 'Seltorexant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HCRTR2 (ENSG00000137252)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1176 | Q59 | What is the genetic target of the small molecule drug Gw-274150, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Gw-274150 is NOS2. Gw-274150 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%gw-274150%" OR LOWER(tradeNames_string) LIKE "%gw-274150%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4087', 'drugName': 'Gw-274150', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NOS2 (ENSG00000007171)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.476 | Q59 | What is the genetic target of the small molecule drug Clometacin, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Clometacin: PTGS2 and PTGS1. Clometacin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%clometacin%" OR LOWER(tradeNames_string) LIKE "%clometacin%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5380', 'drugName': 'Clometacin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.980 | Q59 | What is the genetic target of the small molecule drug Morphine Sulfate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Morphine Sulfate is OPRM1. Morphine Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%morphine sulfate%" OR LOWER(tradeNames_string) LIKE "%morphine sulfa... | [{'UUID': 'DrugGeneTargets_v2_3650', 'drugName': 'Morphine Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1984, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.660 | Q59 | What is the genetic target of the small molecule drug Benzbromarone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Benzbromarone is SLC22A12. Benzbromarone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%benzbromarone%" OR LOWER(tradeNames_string) LIKE "%benzbromarone%" O... | [{'UUID': 'DrugGeneTargets_v2_3284', 'drugName': 'Benzbromarone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC22A12 (ENSG00000197891)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.405 | Q59 | What is the genetic target of the antibody drug Tralokinumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Tralokinumab is IL13. Tralokinumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tralokinumab%" OR LOWER(tradeNames_string) LIKE "%tralokinumab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_6079', 'drugName': 'Tralokinumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL13 (ENSG00000169194)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.517 | Q59 | What is the genetic target of the small molecule drug Tivozanib, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Tivozanib: FLT1, FLT4, KDR, KIT, and PDGFRB. Tivozanib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tivozanib%" OR LOWER(tradeNames_string) LIKE "%tivozanib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_876', 'drugName': 'Tivozanib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052), KIT (ENSG00000157404), PDGFRB (ENSG00000113721)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApprove... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.324 | Q59 | What is the genetic target of the small molecule drug Istradefylline, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Istradefylline is ADORA2A. Istradefylline reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%istradefylline%" OR LOWER(tradeNames_string) LIKE "%istradefylline%"... | [{'UUID': 'DrugGeneTargets_v2_2983', 'drugName': 'Istradefylline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADORA2A (ENSG00000128271)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.20 | Q59 | What is the genetic target of the small molecule drug Naronapride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Naronapride is HTR4. Naronapride reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%naronapride%" OR LOWER(tradeNames_string) LIKE "%naronapride%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_583', 'drugName': 'Naronapride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR4 (ENSG00000164270)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.691 | Q59 | What is the genetic target of the small molecule drug Pyrovalerone Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Pyrovalerone Hydrochloride: SLC6A3 and SLC6A2. Pyrovalerone Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pyrovalerone hydrochloride%" OR LOWER(tradeNames_string) LIKE "%pyro... | [{'UUID': 'DrugGeneTargets_v2_471', 'drugName': 'Pyrovalerone Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.36 | Q59 | What is the genetic target of the small molecule drug Quinapril, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Quinapril is ACE. Quinapril reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%quinapril%" OR LOWER(tradeNames_string) LIKE "%quinapril%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1269', 'drugName': 'Quinapril Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACE (ENSG00000159640)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4605', 'drugName': 'Quinapril', 'drugMolec... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.910 | Q59 | What is the genetic target of the small molecule drug Tranylcypromine Sulfate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Tranylcypromine Sulfate: MAOA and MAOB. Tranylcypromine Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tranylcypromine sulfate%" OR LOWER(tradeNames_string) LIKE "%tranylc... | [{'UUID': 'DrugGeneTargets_v2_1424', 'drugName': 'Tranylcypromine Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAOA (ENSG00000189221), MAOB (ENSG00000069535)', 'yearOfFirstApproval': 1961, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.834 | Q59 | What is the genetic target of the small molecule drug Tetracaine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Tetracaine Hydrochloride: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Tetracaine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tetracaine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%tetrac... | [{'UUID': 'DrugGeneTargets_v2_3723', 'drugName': 'Tetracaine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), S... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1798 | Q59 | What is the genetic target of the small molecule drug Idarubicin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Idarubicin is TOP2A. Idarubicin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%idarubicin%" OR LOWER(tradeNames_string) LIKE "%idarubicin%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5440', 'drugName': 'Idarubicin Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP2A (ENSG00000131747)', 'yearOfFirstApproval': 1990, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_459', 'drugName': 'Idarubicin', 'drugMo... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.413 | Q59 | What is the genetic target of the antibody drug Figitumumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Figitumumab is IGF1R. Figitumumab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%figitumumab%" OR LOWER(tradeNames_string) LIKE "%figitumumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_159', 'drugName': 'Figitumumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IGF1R (ENSG00000140443)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.928 | Q59 | What is the genetic target of the small molecule drug Amiloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Amiloride: SCNN1A, SCNN1B, and SCNN1G. Amiloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%amiloride%" OR LOWER(tradeNames_string) LIKE "%amiloride%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2590', 'drugName': 'Amiloride Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCNN1A (ENSG00000111319), SCNN1B (ENSG00000168447), SCNN1G (ENSG00000166828)', 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGe... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.543 | Q59 | What is the genetic target of the antibody drug Certolizumab Pegol, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Certolizumab Pegol is TNF. Certolizumab Pegol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%certolizumab pegol%" OR LOWER(tradeNames_string) LIKE "%certolizumab... | [{'UUID': 'DrugGeneTargets_v2_5407', 'drugName': 'Certolizumab Pegol', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TNF (ENSG00000232810)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.765 | Q59 | What is the genetic target of the antibody drug Pg-102, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Pg-102 is CD40. Pg-102 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pg-102%" OR LOWER(tradeNames_string) LIKE "%pg-102%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_5276', 'drugName': 'Pg-102', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD40 (ENSG00000101017)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1905 | Q59 | What is the genetic target of the small molecule drug Etalocib, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Etalocib: PPARG and LTB4R. Etalocib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%etalocib%" OR LOWER(tradeNames_string) LIKE "%etalocib%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_4852', 'drugName': 'Etalocib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARG (ENSG00000132170), LTB4R (ENSG00000213903)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_4853', 'drugName': 'Etalocib', '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1071 | Q59 | What is the genetic target of the small molecule drug Dimenhydrinate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dimenhydrinate is HRH1. Dimenhydrinate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dimenhydrinate%" OR LOWER(tradeNames_string) LIKE "%dimenhydrinate%"... | [{'UUID': 'DrugGeneTargets_v2_5219', 'drugName': 'Dimenhydrinate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1972, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1209 | Q59 | What is the genetic target of the small molecule drug Apraclonidine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Apraclonidine Hydrochloride: ADRA2A, ADRA2C, and ADRA2B. Apraclonidine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%apraclonidine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%apr... | [{'UUID': 'DrugGeneTargets_v2_2038', 'drugName': 'Apraclonidine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 1987, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.248 | Q59 | What is the genetic target of the small molecule drug Bms-817378, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Bms-817378: MET and KDR. Bms-817378 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bms-817378%" OR LOWER(tradeNames_string) LIKE "%bms-817378%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2709', 'drugName': 'Bms-817378', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MET (ENSG00000105976), KDR (ENSG00000128052)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_2710', 'drugName': 'Bms-817378', '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1431 | Q59 | What is the genetic target of the small molecule drug Anileridine Phosphate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Anileridine Phosphate: OPRM1 and OPRK1. Anileridine Phosphate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%anileridine phosphate%" OR LOWER(tradeNames_string) LIKE "%anileridi... | [{'UUID': 'DrugGeneTargets_v2_4938', 'drugName': 'Anileridine Phosphate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038), OPRK1 (ENSG00000082556)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4939', 'drugName'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1137 | Q59 | What is the genetic target of the small molecule drug Valrubicin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Valrubicin is TOP2A. Valrubicin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%valrubicin%" OR LOWER(tradeNames_string) LIKE "%valrubicin%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_484', 'drugName': 'Doxorubicin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP2A (ENSG00000131747)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_881', 'drugName': 'Daunorubicin', 'drugMolecularType': '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.791 | Q59 | What is the genetic target of the small molecule drug Acalabrutinib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Acalabrutinib is BTK. Acalabrutinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%acalabrutinib%" OR LOWER(tradeNames_string) LIKE "%acalabrutinib%" O... | [{'UUID': 'DrugGeneTargets_v2_593', 'drugName': 'Acalabrutinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BTK (ENSG00000010671)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6297', 'drugName': 'Acalabrutinib Maleate', 'drugMole... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1744 | Q59 | What is the genetic target of the small molecule drug Pf-05175157, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Pf-05175157: ACACA and ACACB. Pf-05175157 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pf-05175157%" OR LOWER(tradeNames_string) LIKE "%pf-05175157%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2356', 'drugName': 'Pf-05175157', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACACA (ENSG00000278540), ACACB (ENSG00000076555)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.495 | Q59 | What is the genetic target of the protein drug Peginterferon Alfa-2A, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the protein drug Peginterferon Alfa-2A: IFNAR1 and IFNAR2. Peginterferon Alfa-2A reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%peginterferon alfa-2a%" OR LOWER(tradeNames_string) LIKE "%peginterf... | [{'UUID': 'DrugGeneTargets_v2_3511', 'drugName': 'Peginterferon Alfa-2A', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'IFNAR1 (ENSG00000142166), IFNAR2 (ENSG00000159110)', 'yearOfFirstApproval': 2002, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.157 | Q59 | What is the genetic target of the small molecule drug Larotrectinib, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Larotrectinib: NTRK1, NTRK2, and NTRK3. Larotrectinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%larotrectinib%" OR LOWER(tradeNames_string) LIKE "%larotrectinib%" O... | [{'UUID': 'DrugGeneTargets_v2_894', 'drugName': 'Larotrectinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NTRK1 (ENSG00000198400), NTRK2 (ENSG00000148053), NTRK3 (ENSG00000140538)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.970 | Q59 | What is the genetic target of the antibody drug Cetuximab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Cetuximab is EGFR. Cetuximab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cetuximab%" OR LOWER(tradeNames_string) LIKE "%cetuximab%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1080', 'drugName': 'Cetuximab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'EGFR (ENSG00000146648)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3231', 'drugName': 'Cetuximab Sarotalocan', 'drugMolecularTyp... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.860 | Q59 | What is the genetic target of the antibody drug Nerelimomab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Nerelimomab is TNF. Nerelimomab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nerelimomab%" OR LOWER(tradeNames_string) LIKE "%nerelimomab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1151', 'drugName': 'Nerelimomab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TNF (ENSG00000232810)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1325 | Q59 | What is the genetic target of the small molecule drug Mivacurium, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Mivacurium: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Mivacurium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mivacurium%" OR LOWER(tradeNames_string) LIKE "%mivacurium%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3976', 'drugName': 'Mivacurium Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1992, 'maxClinicalTrialPhase':... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.632 | Q59 | What is the genetic target of the antibody drug Mdx-1342, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Mdx-1342 is CD19. Mdx-1342 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mdx-1342%" OR LOWER(tradeNames_string) LIKE "%mdx-1342%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_3279', 'drugName': 'Mdx-1342', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD19 (ENSG00000177455)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.692 | Q59 | What is the genetic target of the small molecule drug Roxadustat, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Roxadustat: EGLN2, P4HTM, EGLN1, and EGLN3. Roxadustat reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%roxadustat%" OR LOWER(tradeNames_string) LIKE "%roxadustat%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5393', 'drugName': 'Roxadustat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGLN2 (ENSG00000269858), P4HTM (ENSG00000178467), EGLN1 (ENSG00000135766), EGLN3 (ENSG00000129521)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1562 | Q59 | What is the genetic target of the small molecule drug Clonidine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Clonidine: ADRA2A, ADRA2C, and ADRA2B. Clonidine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%clonidine%" OR LOWER(tradeNames_string) LIKE "%clonidine%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4092', 'drugName': 'Clonidine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 1974, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGe... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.575 | Q59 | What is the genetic target of the small molecule drug Divalproex Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Divalproex Sodium is ALDH5A1. Divalproex Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%divalproex sodium%" OR LOWER(tradeNames_string) LIKE "%divalproex so... | [{'UUID': 'DrugGeneTargets_v2_5683', 'drugName': 'Divalproex Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ALDH5A1 (ENSG00000112294)', 'yearOfFirstApproval': 1983, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1909 | Q59 | What is the genetic target of the small molecule drug Dextrothyroxine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Dextrothyroxine: THRA and THRB. Dextrothyroxine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dextrothyroxine%" OR LOWER(tradeNames_string) LIKE "%dextrothyroxine... | [{'UUID': 'DrugGeneTargets_v2_4368', 'drugName': 'Dextrothyroxine Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'THRA (ENSG00000126351), THRB (ENSG00000151090)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4459', 'drugName':... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.18 | Q59 | What is the genetic target of the protein drug Efgartigimod Alfa, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Efgartigimod Alfa is FCGRT. Efgartigimod Alfa reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%efgartigimod alfa%" OR LOWER(tradeNames_string) LIKE "%efgartigimod ... | [{'UUID': 'DrugGeneTargets_v2_4154', 'drugName': 'Efgartigimod Alfa', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'FCGRT (ENSG00000104870)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.130 | Q59 | What is the genetic target of the small molecule drug Propoxyphene Napsylate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Propoxyphene Napsylate is OPRM1. Propoxyphene Napsylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%propoxyphene napsylate%" OR LOWER(tradeNames_string) LIKE "%propoxyp... | [{'UUID': 'DrugGeneTargets_v2_303', 'drugName': 'Propoxyphene Napsylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1971, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1361 | Q59 | What is the genetic target of the small molecule drug Spironolactone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Spironolactone is NR3C2. Spironolactone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%spironolactone%" OR LOWER(tradeNames_string) LIKE "%spironolactone%"... | [{'UUID': 'DrugGeneTargets_v2_2455', 'drugName': 'Spironolactone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C2 (ENSG00000151623)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4514', 'drugName': 'Canrenone', 'drugMolecularTyp... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1291 | Q59 | What is the genetic target of the small molecule drug Fosdagrocorat, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fosdagrocorat is NR3C1. Fosdagrocorat reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fosdagrocorat%" OR LOWER(tradeNames_string) LIKE "%fosdagrocorat%" O... | [{'UUID': 'DrugGeneTargets_v2_2507', 'drugName': 'Fosdagrocorat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1969 | Q59 | What is the genetic target of the protein drug Tirzepatide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the protein drug Tirzepatide: GIPR and GLP1R. Tirzepatide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tirzepatide%" OR LOWER(tradeNames_string) LIKE "%tirzepatide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5134', 'drugName': 'Tirzepatide', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GIPR (ENSG00000010310), GLP1R (ENSG00000112164)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5135', 'drugName': 'Tirzepatide', '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.935 | Q59 | What is the genetic target of the small molecule drug Fosinopril, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fosinopril is ACE. Fosinopril reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fosinopril%" OR LOWER(tradeNames_string) LIKE "%fosinopril%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2110', 'drugName': 'Fosinopril', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACE (ENSG00000159640)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2506', 'drugName': 'Fosinopril Sodium', 'drugMolecularT... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.989 | Q59 | What is the genetic target of the small molecule drug Mitoxantrone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mitoxantrone is TOP2A. Mitoxantrone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mitoxantrone%" OR LOWER(tradeNames_string) LIKE "%mitoxantrone%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4715', 'drugName': 'Mitoxantrone Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP2A (ENSG00000131747)', 'yearOfFirstApproval': 1987, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2577', 'drugName': 'Mitoxantrone', 'd... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1965 | Q59 | What is the genetic target of the small molecule drug Eletriptan, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Eletriptan: HTR1F, HTR1D, and HTR1B. Eletriptan reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%eletriptan%" OR LOWER(tradeNames_string) LIKE "%eletriptan%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3982', 'drugName': 'Eletriptan Hydrobromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1F (ENSG00000179097), HTR1D (ENSG00000179546), HTR1B (ENSG00000135312)', 'yearOfFirstApproval': 2002, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneT... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.193 | Q59 | What is the genetic target of the small molecule drug Nifedipine, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Nifedipine: CACNA1C, CACNA1S, CACNA1D, and CACNA1F. Nifedipine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nifedipine%" OR LOWER(tradeNames_string) LIKE "%nifedipine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3465', 'drugName': 'Nifedipine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001)', 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1149 | Q59 | What is the genetic target of the small molecule drug Alpelisib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Alpelisib is PIK3CA. Alpelisib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alpelisib%" OR LOWER(tradeNames_string) LIKE "%alpelisib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_722', 'drugName': 'Alpelisib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PIK3CA (ENSG00000121879)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1001 | Q59 | What is the genetic target of the small molecule drug Gefitinib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Gefitinib is EGFR. Gefitinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%gefitinib%" OR LOWER(tradeNames_string) LIKE "%gefitinib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4972', 'drugName': 'Gefitinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGFR (ENSG00000146648)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1956 | Q59 | What is the genetic target of the small molecule drug Baclofen, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Baclofen: GABBR1 and GABBR2. Baclofen reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%baclofen%" OR LOWER(tradeNames_string) LIKE "%baclofen%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_3627', 'drugName': 'Baclofen', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GABBR1 (ENSG00000204681), GABBR2 (ENSG00000136928)', 'yearOfFirstApproval': 1977, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_336', 'drugName': 'Arbaclofe... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1657 | Q59 | What is the genetic target of the small molecule drug Ticlopidine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ticlopidine Hydrochloride is P2RY12. Ticlopidine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ticlopidine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%ticlo... | [{'UUID': 'DrugGeneTargets_v2_1201', 'drugName': 'Ticlopidine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'P2RY12 (ENSG00000169313)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.613 | Q59 | What is the genetic target of the small molecule drug Dapiprazole, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dapiprazole is ADRA1A. Dapiprazole reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dapiprazole%" OR LOWER(tradeNames_string) LIKE "%dapiprazole%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5119', 'drugName': 'Dapiprazole', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907)', 'yearOfFirstApproval': 1990, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_322', 'drugName': 'Dapiprazole Hydrochloride', 'dru... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.183 | Q59 | What is the genetic target of the small molecule drug Selonsertib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Selonsertib is MAP3K5. Selonsertib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%selonsertib%" OR LOWER(tradeNames_string) LIKE "%selonsertib%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5336', 'drugName': 'Selonsertib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAP3K5 (ENSG00000197442)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.305 | Q59 | What is the genetic target of the small molecule drug Quinestrol, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Quinestrol: ESR2 and ESR1. Quinestrol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%quinestrol%" OR LOWER(tradeNames_string) LIKE "%quinestrol%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4010', 'drugName': 'Quinestrol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009), ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.502 | Q59 | What is the genetic target of the small molecule drug Solifenacin, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Solifenacin: CHRM2 and CHRM3. Solifenacin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%solifenacin%" OR LOWER(tradeNames_string) LIKE "%solifenacin%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3331', 'drugName': 'Solifenacin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM2 (ENSG00000181072), CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3330', 'drugName': 'Solifen... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1696 | Q59 | What is the genetic target of the small molecule drug Nitric Oxide, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Nitric Oxide: GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. Nitric Oxide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nitric oxide%" OR LOWER(tradeNames_string) LIKE "%nitric oxide%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2884', 'drugName': 'Nitric Oxide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GUCY1B1 (ENSG00000061918), GUCY1B2 (ENSG00000123201), GUCY1A2 (ENSG00000152402), GUCY1A1 (ENSG00000164116)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1721 | Q59 | What is the genetic target of the small molecule drug Abt-639, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Abt-639 is CACNA1H. Abt-639 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%abt-639%" OR LOWER(tradeNames_string) LIKE "%abt-639%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_3161', 'drugName': 'Abt-639', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1H (ENSG00000196557)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1662 | Q59 | What is the genetic target of the antibody drug Risankizumab, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the antibody drug Risankizumab: IL12B and IL23A. Risankizumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%risankizumab%" OR LOWER(tradeNames_string) LIKE "%risankizumab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_6358', 'drugName': 'Risankizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL12B (ENSG00000113302), IL23A (ENSG00000110944)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1639 | Q59 | What is the genetic target of the small molecule drug Bicifadine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Bicifadine: SLC6A4, SLC6A3, and SLC6A2. Bicifadine reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bicifadine%" OR LOWER(tradeNames_string) LIKE "%bicifadine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6135', 'drugName': 'Bicifadine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.523 | Q59 | What is the genetic target of the small molecule drug Naproxen Etemesil, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Naproxen Etemesil: PTGS2 and PTGS1. Naproxen Etemesil reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%naproxen etemesil%" OR LOWER(tradeNames_string) LIKE "%naproxen etem... | [{'UUID': 'DrugGeneTargets_v2_5387', 'drugName': 'Naproxen Etemesil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1985 | Q59 | What is the genetic target of the small molecule drug Tolazamide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Tolazamide: KCNJ11 and ABCC8. Tolazamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tolazamide%" OR LOWER(tradeNames_string) LIKE "%tolazamide%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2335', 'drugName': 'Tolazamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KCNJ11 (ENSG00000187486), ABCC8 (ENSG00000006071)', 'yearOfFirstApproval': 1966, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1078 | Q59 | What is the genetic target of the small molecule drug Sotalol, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Sotalol: ADRB1, KCNH2, and ADRB2. Sotalol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sotalol%" OR LOWER(tradeNames_string) LIKE "%sotalol%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_4571', 'drugName': 'Sotalol Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591), KCNH2 (ENSG00000055118), ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1992, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTar... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.482 | Q59 | What is the genetic target of the small molecule drug Risedronic Acid, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Risedronic Acid is FDPS. Risedronic Acid reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%risedronic acid%" OR LOWER(tradeNames_string) LIKE "%risedronic acid... | [{'UUID': 'DrugGeneTargets_v2_4717', 'drugName': 'Risedronate Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FDPS (ENSG00000160752)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1294', 'drugName': 'Risedronic Acid', 'drugMol... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.160 | Q59 | What is the genetic target of the small molecule drug Zandelisib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Zandelisib is PIK3CD. Zandelisib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%zandelisib%" OR LOWER(tradeNames_string) LIKE "%zandelisib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5341', 'drugName': 'Zandelisib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PIK3CD (ENSG00000171608)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1253 | Q59 | What is the genetic target of the small molecule drug Fingolimod Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Fingolimod Hydrochloride: S1PR5, S1PR2, S1PR4, S1PR3, and S1PR1. Fingolimod Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fingolimod hydrochloride%" OR LOWER(tradeNames_string) LIKE "%fingol... | [{'UUID': 'DrugGeneTargets_v2_4765', 'drugName': 'Fingolimod Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'S1PR5 (ENSG00000180739), S1PR2 (ENSG00000267534), S1PR4 (ENSG00000125910), S1PR3 (ENSG00000213694), S1PR1 (ENSG00000170989)', 'yearOfFirstApproval': 2010, 'maxClinicalTrialPhas... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1205 | Q59 | What is the genetic target of the small molecule drug Arformoterol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Arformoterol is ADRB2. Arformoterol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%arformoterol%" OR LOWER(tradeNames_string) LIKE "%arformoterol%" OR ... | [{'UUID': 'DrugGeneTargets_v2_440', 'drugName': 'Arformoterol Tartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 2006, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6308', 'drugName': 'Arformoterol', 'drugMol... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
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