uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
values |
|---|---|---|---|---|---|---|---|---|
Q67.1005 | Q67 | What is the top-associated SNP of the gene RN7SL656P in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RN7SL656P in Prefrontal Cortex eQTL omic data for AD is rs199447, which has a multi-SNP SMR p-value of 7.31e-07 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RN7SL656P" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203017', 'topRSID': 'rs199447', 'Disease': 'AD', 'Gene': 'RN7SL656P', 'p_SMR_multi': 7.310742e-07, 'p_HEIDI': 0.0240069, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.156 | Q67 | What is the top-associated SNP of the gene RP11-521O16.1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-521O16.1 in Whole Blood mQTL omic data for AD is rs2404175, which has a multi-SNP SMR p-value of 7.19e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-521O16.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_631109', 'topRSID': 'rs77571924', 'Disease': 'AD', 'Gene': 'RP11-521O16.1', 'p_SMR_multi': 4.4846810000000005e-17, 'p_HEIDI': 1.460436e-09, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1108 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 2.40e-28 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041740', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 3.1929999999999995e-44, 'p_HEIDI': 3.11336e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1719 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD is rs62065379, which has a multi-SNP SMR p-value of 2.16e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491057', 'topRSID': 'rs62065376', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 1.134698e-11, 'p_HEIDI': 0.3072466, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1998 | Q67 | What is the top-associated SNP of the gene IDUA in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IDUA in Whole Blood mQTL omic data for PD is rs188911015, which has a multi-SNP SMR p-value of 2.30e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IDUA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996313', 'topRSID': 'rs11936407', 'Disease': 'PD', 'Gene': 'IDUA', 'p_SMR_multi': 1.158943e-09, 'p_HEIDI': 4.775076e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.796 | Q67 | What is the top-associated SNP of the gene DDX42 in Cerebellar Hemisphere eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene DDX42 in Cerebellar Hemisphere eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DDX42" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1187055', 'topRSID': 'rs8081541', 'Disease': 'LBD', 'Gene': 'DDX42', 'p_SMR_multi': 0.954908, 'p_HEIDI': 0.9471317, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.587 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Frontal Cortex BA9 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Frontal Cortex BA9 eQTL omic data for PD is rs199533, which has a multi-SNP SMR p-value of 9.22e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1168835', 'topRSID': 'rs199533', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 9.2192e-12, 'p_HEIDI': 0.0049541, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.710 | Q67 | What is the top-associated SNP of the gene CTB-171A8.1 in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CTB-171A8.1 in Prefrontal Cortex eQTL omic data for AD is rs79638902, which has a multi-SNP SMR p-value of 4.04e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTB-171A8.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203797', 'topRSID': 'rs79638902', 'Disease': 'AD', 'Gene': 'CTB-171A8.1', 'p_SMR_multi': 4.039964e-14, 'p_HEIDI': 1.189533e-10, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1222 | Q67 | What is the top-associated SNP of the gene RP11-798G7.8 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for RP11-798G7.8 in Whole Blood eQTL eQTLgen omic data for PD is rs113564729, which has a multi-SNP SMR p-value of 7.04e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-798G7.8" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1564778', 'topRSID': 'rs113564729', 'Disease': 'PD', 'Gene': 'RP11-798G7.8', 'p_SMR_multi': 7.036133e-09, 'p_HEIDI': 5.972018e-11, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1308 | Q67 | What is the top-associated SNP of the gene TSPAN14 in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for TSPAN14 in Cortex eQTL metaBrain omic data for AD is rs10749609, which has a multi-SNP SMR p-value of 1.59e-07 and a HEIDI of 0.9, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TSPAN14" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1105563', 'topRSID': 'rs10749609', 'Disease': 'AD', 'Gene': 'TSPAN14', 'p_SMR_multi': 1.590519e-07, 'p_HEIDI': 0.8979075, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1666 | Q67 | What is the top-associated SNP of the gene TFAM in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene TFAM in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TFAM" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_461001', 'topRSID': 'rs150887692', 'Disease': 'PD', 'Gene': 'TFAM', 'p_SMR_multi': 0.1223198, 'p_HEIDI': 0.2487909, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_4... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1270 | Q67 | What is the top-associated SNP of the gene ADAMTS4 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for ADAMTS4 in Whole Blood mQTL omic data for AD is rs34884997, which has a multi-SNP SMR p-value of 2.30e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ADAMTS4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_654684', 'topRSID': 'rs34884997', 'Disease': 'AD', 'Gene': 'ADAMTS4', 'p_SMR_multi': 2.296954e-06, 'p_HEIDI': 0.00134174, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.493 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Liver eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Liver eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.47e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1478188', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 1.474329e-18, 'p_HEIDI': 3.267957e-15, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.565 | Q67 | What is the top-associated SNP of the gene LINC00658 in Whole Blood mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene LINC00658 in Whole Blood mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LINC00658" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_580418', 'topRSID': 'rs4815820', 'Disease': 'AD', 'Gene': 'LINC00658', 'p_SMR_multi': 0.4074205, 'p_HEIDI': 0.7457917, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_580419', 'to... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1151 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Hypothalamus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Hypothalamus eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 1.15e-11 and a HEIDI of 0.35, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1462897', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 1.146115e-11, 'p_HEIDI': 0.346278, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1129 | Q67 | What is the top-associated SNP of the gene IGSF9B in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IGSF9B in Whole Blood mQTL omic data for PD is rs11223621, which has a multi-SNP SMR p-value of 9.60e-10 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IGSF9B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_961101', 'topRSID': 'rs3802920', 'Disease': 'PD', 'Gene': 'IGSF9B', 'p_SMR_multi': 1.22563e-10, 'p_HEIDI': 0.0001625568, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.808 | Q67 | What is the top-associated SNP of the gene SETD1A in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD and is it functionally significant? | The top-associated SNP for SETD1A in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD is rs12934900, which has a multi-SNP SMR p-value of 1.94e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SETD1A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1435341', 'topRSID': 'rs12934900', 'Disease': 'PD', 'Gene': 'SETD1A', 'p_SMR_multi': 1.93981e-06, 'p_HEIDI': 3.799415e-10, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thres... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.518 | Q67 | What is the top-associated SNP of the gene PILRB in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PILRB in Skeletal Muscle eQTL omic data for AD is rs7799901, which has a multi-SNP SMR p-value of 1.26e-06 and a HEIDI of 0.21, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PILRB" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1340321', 'topRSID': 'rs7799901', 'Disease': 'AD', 'Gene': 'PILRB', 'p_SMR_multi': 1.260226e-06, 'p_HEIDI': 0.2083771, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.640 | Q67 | What is the top-associated SNP of the gene CTD-2020K17.1 in Cerebellum eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for CTD-2020K17.1 in Cerebellum eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 9.88e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTD-2020K17.1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1714144', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'CTD-2020K17.1', 'p_SMR_multi': 9.875865e-09, 'p_HEIDI': 0.007677051, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1480 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Cortex eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Cortex eQTL GTEx omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 5.03e-13 and a HEIDI of 0.68, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1262225', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 5.034906e-13, 'p_HEIDI': 0.6751382, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1789 | Q67 | What is the top-associated SNP of the gene WNT3 in Cortex eQTL metaBrain omic data for PSP and is it functionally significant? | The top-associated SNP for WNT3 in Cortex eQTL metaBrain omic data for PSP is rs8069437, which has a multi-SNP SMR p-value of 9.26e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "WNT3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1154402', 'topRSID': 'rs8069437', 'Disease': 'PSP', 'Gene': 'WNT3', 'p_SMR_multi': 9.262221e-18, 'p_HEIDI': 1.20707e-08, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1546 | Q67 | What is the top-associated SNP of the gene CR1 in Whole Brain eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CR1 in Whole Brain eQTL omic data for AD is rs679515, which has a multi-SNP SMR p-value of 2.10e-12 and a HEIDI of 0.26, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CR1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1605472', 'topRSID': 'rs679515', 'Disease': 'AD', 'Gene': 'CR1', 'p_SMR_multi': 2.099284e-12, 'p_HEIDI': 0.2568474, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1160 | Q67 | What is the top-associated SNP of the gene LMOD3 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene LMOD3 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LMOD3" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_679362', 'topRSID': 'rs9842761', 'Disease': 'ALS', 'Gene': 'LMOD3', 'p_SMR_multi': 0.207845, 'p_HEIDI': 0.7957609, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_679361', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.797 | Q67 | What is the top-associated SNP of the gene EPHX2 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for EPHX2 in Whole Brain meta-analysis mQTL omic data for AD is rs10096092, which has a multi-SNP SMR p-value of 7.95e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHX2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_78248', 'topRSID': 'rs73227337', 'Disease': 'AD', 'Gene': 'EPHX2', 'p_SMR_multi': 1.500668e-09, 'p_HEIDI': 0.01595741, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_78... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.119 | Q67 | What is the top-associated SNP of the gene C7orf61 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for C7orf61 in Whole Blood eQTL eQTLgen omic data for AD is rs7787620, which has a multi-SNP SMR p-value of 3.81e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C7orf61" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495811', 'topRSID': 'rs7787620', 'Disease': 'AD', 'Gene': 'C7orf61', 'p_SMR_multi': 3.813436e-08, 'p_HEIDI': 5.630473e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.747 | Q67 | What is the top-associated SNP of the gene IDUA in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IDUA in Whole Brain meta-analysis mQTL omic data for PD is rs6599388, which has a multi-SNP SMR p-value of 1.87e-12 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IDUA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429873', 'topRSID': 'rs1051613', 'Disease': 'PD', 'Gene': 'IDUA', 'p_SMR_multi': 4.554749e-13, 'p_HEIDI': 2.213052e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1691 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Cerebellar Hemisphere eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Cerebellar Hemisphere eQTL omic data for AD is rs55974014, which has a multi-SNP SMR p-value of 2.83e-06 and a HEIDI of 0.76, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1174600', 'topRSID': 'rs55974014', 'Disease': 'AD', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 2.826981e-06, 'p_HEIDI': 0.7607059, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1090 | Q67 | What is the top-associated SNP of the gene APOC4 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOC4 in Whole Brain meta-analysis mQTL omic data for AD is rs7259679, which has a multi-SNP SMR p-value of 2.48e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122468', 'topRSID': 'rs11878597', 'Disease': 'AD', 'Gene': 'APOC4', 'p_SMR_multi': 1.942575e-13, 'p_HEIDI': 5.901231e-09, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.837 | Q67 | What is the top-associated SNP of the gene CNN2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CNN2 in Whole Blood mQTL omic data for AD is rs111745465, which has a multi-SNP SMR p-value of 4.47e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CNN2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_634277', 'topRSID': 'rs7247087', 'Disease': 'AD', 'Gene': 'CNN2', 'p_SMR_multi': 1.304171e-10, 'p_HEIDI': 9.291437e-15, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.122 | Q67 | What is the top-associated SNP of the gene BTNL2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for BTNL2 in Whole Blood mQTL omic data for AD is rs115303880, which has a multi-SNP SMR p-value of 1.32e-06 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BTNL2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621688', 'topRSID': 'rs116522341', 'Disease': 'AD', 'Gene': 'BTNL2', 'p_SMR_multi': 2.681311e-09, 'p_HEIDI': 2.28461e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.663 | Q67 | What is the top-associated SNP of the gene NFYA in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for NFYA in Whole Blood mQTL omic data for AD is rs62396353, which has a multi-SNP SMR p-value of 5.92e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NFYA" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_622639', 'topRSID': 'rs72856298', 'Disease': 'AD', 'Gene': 'NFYA', 'p_SMR_multi': 3.336665e-10, 'p_HEIDI': 1.123977e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1908 | Q67 | What is the top-associated SNP of the gene DND1P1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for DND1P1 in Whole Blood mQTL omic data for AD is rs199447, which has a multi-SNP SMR p-value of 1.52e-06 and a HEIDI of 0.1, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_591167', 'topRSID': 'rs199447', 'Disease': 'AD', 'Gene': 'DND1P1', 'p_SMR_multi': 1.52052e-06, 'p_HEIDI': 0.1016157, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.642 | Q67 | What is the top-associated SNP of the gene DND1P1 in Liver eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for DND1P1 in Liver eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 2.01e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1478184', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'DND1P1', 'p_SMR_multi': 2.006353e-18, 'p_HEIDI': 3.915164e-20, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.374 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Whole Blood eQTL GTEx omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Whole Blood eQTL GTEx omic data for PSP is rs12373139, which has a multi-SNP SMR p-value of 3.70e-36 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1684937', 'topRSID': 'rs12373139', 'Disease': 'PSP', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 3.696455e-36, 'p_HEIDI': 1.294555e-18, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.271 | Q67 | What is the top-associated SNP of the gene GPNMB in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for GPNMB in Whole Brain meta-analysis mQTL omic data for PD is rs466225, which has a multi-SNP SMR p-value of 5.06e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPNMB" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_447897', 'topRSID': 'rs199357', 'Disease': 'PD', 'Gene': 'GPNMB', 'p_SMR_multi': 1.890519e-08, 'p_HEIDI': 0.02394197, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_447... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.662 | Q67 | What is the top-associated SNP of the gene EPHX2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for EPHX2 in Whole Blood mQTL omic data for AD is rs6994778, which has a multi-SNP SMR p-value of 2.98e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHX2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_615760', 'topRSID': 'rs36081056', 'Disease': 'AD', 'Gene': 'EPHX2', 'p_SMR_multi': 1.65609e-08, 'p_HEIDI': 4.983638e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.944 | Q67 | What is the top-associated SNP of the gene PYCR1 in Cerebellum eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene PYCR1 in Cerebellum eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PYCR1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_19749', 'topRSID': 'rs35878485', 'Disease': 'PD', 'Gene': 'PYCR1', 'p_SMR_multi': 0.007832005, 'p_HEIDI': 0.1056864, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.829 | Q67 | What is the top-associated SNP of the gene TSC22D1 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene TSC22D1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TSC22D1" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_288309', 'topRSID': 'rs1053948', 'Disease': 'FTD', 'Gene': 'TSC22D1', 'p_SMR_multi': 0.2274687, 'p_HEIDI': 0.701981, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.873 | Q67 | What is the top-associated SNP of the gene CTD-2113L7.1 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene CTD-2113L7.1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTD-2113L7.1" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_341580', 'topRSID': 'rs11957963', 'Disease': 'LBD', 'Gene': 'CTD-2113L7.1', 'p_SMR_multi': 0.6030036, 'p_HEIDI': 0.2976336, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_updat... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.47 | Q67 | What is the top-associated SNP of the gene AC034220.3 in Whole Brain eQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene AC034220.3 in Whole Brain eQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC034220.3" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1621844', 'topRSID': 'rs272869', 'Disease': 'FTD', 'Gene': 'AC034220.3', 'p_SMR_multi': 0.9503712, 'p_HEIDI': 0.9301381, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1388 | Q67 | What is the top-associated SNP of the gene DND1P1 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for DND1P1 in Whole Brain meta-analysis mQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 2.27e-22 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560847', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'DND1P1', 'p_SMR_multi': 2.2711060000000003e-22, 'p_HEIDI': 6.766314e-09, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1709 | Q67 | What is the top-associated SNP of the gene LRRC37A in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A in Cerebellum eQTL omic data for AD is rs4510068, which has a multi-SNP SMR p-value of 1.06e-06 and a HEIDI of 0.63, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1690051', 'topRSID': 'rs4510068', 'Disease': 'AD', 'Gene': 'LRRC37A', 'p_SMR_multi': 1.056725e-06, 'p_HEIDI': 0.6262373, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_2658', 'topRSID'... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1000 | Q67 | What is the top-associated SNP of the gene CLMP in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene CLMP in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CLMP" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_375123', 'topRSID': 'rs11603215', 'Disease': 'LBD', 'Gene': 'CLMP', 'p_SMR_multi': 0.5590513, 'p_HEIDI': 0.9218238, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_3... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.883 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Tibial Nerve eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A4P in Tibial Nerve eQTL omic data for PD is rs1724390, which has a multi-SNP SMR p-value of 6.93e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1328924', 'topRSID': 'rs1724390', 'Disease': 'PD', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 6.929096e-14, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.780 | Q67 | What is the top-associated SNP of the gene REXO1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for REXO1 in Whole Blood mQTL omic data for AD is rs4453627, which has a multi-SNP SMR p-value of 2.02e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "REXO1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_634424', 'topRSID': 'rs4453627', 'Disease': 'AD', 'Gene': 'REXO1', 'p_SMR_multi': 2.017244e-08, 'p_HEIDI': 2.408255e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1229 | Q67 | What is the top-associated SNP of the gene RP11-196G11.2 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for RP11-196G11.2 in Whole Blood eQTL eQTLgen omic data for PD is rs58726213, which has a multi-SNP SMR p-value of 3.24e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-196G11.2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1563811', 'topRSID': 'rs58726213', 'Disease': 'PD', 'Gene': 'RP11-196G11.2', 'p_SMR_multi': 3.242841e-08, 'p_HEIDI': 2.612459e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.2000 | Q67 | What is the top-associated SNP of the gene BCKDK in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for BCKDK in Whole Blood eQTL eQTLgen omic data for AD is rs4889619, which has a multi-SNP SMR p-value of 7.33e-08 and a HEIDI of 0.41, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BCKDK" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501480', 'topRSID': 'rs4889619', 'Disease': 'AD', 'Gene': 'BCKDK', 'p_SMR_multi': 7.332338e-08, 'p_HEIDI': 0.4073159, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.5 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Caudate Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Caudate Basal Ganglia eQTL omic data for PD is rs199533, which has a multi-SNP SMR p-value of 4.07e-12 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1281355', 'topRSID': 'rs199533', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 4.067206e-12, 'p_HEIDI': 0.01217283, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1012 | Q67 | What is the top-associated SNP of the gene RP11-468N14.13 in Cerebellar Hemisphere eQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene RP11-468N14.13 in Cerebellar Hemisphere eQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-468N14.13" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1192625', 'topRSID': 'rs11724856', 'Disease': 'PSP', 'Gene': 'RP11-468N14.13', 'p_SMR_multi': 0.7447462, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1724 | Q67 | What is the top-associated SNP of the gene RP11-113D6.10 in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene RP11-113D6.10 in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-113D6.10" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_186232', 'topRSID': 'rs2445225', 'Disease': 'ALS', 'Gene': 'RP11-113D6.10', 'p_SMR_multi': 0.2888465, 'p_HEIDI': 0.5763802, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_updat... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.266 | Q67 | What is the top-associated SNP of the gene PLEKHM1 in Nucleus Accumbens Basal Ganglia omic data for PD and is it functionally significant? | The top-associated SNP for PLEKHM1 in Nucleus Accumbens Basal Ganglia omic data for PD is rs10445367, which has a multi-SNP SMR p-value of 3.93e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLEKHM1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1730057', 'topRSID': 'rs10445367', 'Disease': 'PD', 'Gene': 'PLEKHM1', 'p_SMR_multi': 3.928019e-09, 'p_HEIDI': 0.002772246, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance threshold but shows s... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1570 | Q67 | What is the top-associated SNP of the gene MCF2L in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene MCF2L in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MCF2L" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_197044', 'topRSID': 'rs2993289', 'Disease': 'ALS', 'Gene': 'MCF2L', 'p_SMR_multi': 0.08625802, 'p_HEIDI': 0.05953705, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1832 | Q67 | What is the top-associated SNP of the gene PLEKHM1 in Cerebellar Hemisphere eQTL omic data for PD and is it functionally significant? | The top-associated SNP for PLEKHM1 in Cerebellar Hemisphere eQTL omic data for PD is rs4383188, which has a multi-SNP SMR p-value of 4.40e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLEKHM1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1191162', 'topRSID': 'rs4383188', 'Disease': 'PD', 'Gene': 'PLEKHM1', 'p_SMR_multi': 4.397564e-11, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'association meets significance threshold but shows signs of link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.449 | Q67 | What is the top-associated SNP of the gene MARK4 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MARK4 in Whole Blood mQTL omic data for AD is rs12459074, which has a multi-SNP SMR p-value of 2.62e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MARK4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_637449', 'topRSID': 'rs10409232', 'Disease': 'AD', 'Gene': 'MARK4', 'p_SMR_multi': 1.728605e-11, 'p_HEIDI': 2.720626e-14, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1011 | Q67 | What is the top-associated SNP of the gene SEPT9 in Whole Blood mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene SEPT9 in Whole Blood mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SEPT9" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_592706', 'topRSID': 'rs1436138', 'Disease': 'AD', 'Gene': 'SEPT9', 'p_SMR_multi': 0.09764214, 'p_HEIDI': 0.1657574, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_592699', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1086 | Q67 | What is the top-associated SNP of the gene CTB-171A8.1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CTB-171A8.1 in Whole Brain meta-analysis mQTL omic data for AD is rs12985368, which has a multi-SNP SMR p-value of 1.15e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTB-171A8.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122446', 'topRSID': 'rs10410915', 'Disease': 'AD', 'Gene': 'CTB-171A8.1', 'p_SMR_multi': 3.296369e-08, 'p_HEIDI': 0.0001542126, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of l... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.844 | Q67 | What is the top-associated SNP of the gene CLU in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CLU in Whole Brain meta-analysis mQTL omic data for AD is rs1532278, which has a multi-SNP SMR p-value of 3.62e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CLU" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_78262', 'topRSID': 'rs7982', 'Disease': 'AD', 'Gene': 'CLU', 'p_SMR_multi': 2.501744e-10, 'p_HEIDI': 6.84878e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1792 | Q67 | What is the top-associated SNP of the gene CEACAM19 in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CEACAM19 in Prefrontal Cortex eQTL omic data for AD is rs56261258, which has a multi-SNP SMR p-value of 2.35e-08 and a HEIDI of 0.12, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CEACAM19" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203796', 'topRSID': 'rs56261258', 'Disease': 'AD', 'Gene': 'CEACAM19', 'p_SMR_multi': 2.346122e-08, 'p_HEIDI': 0.1158474, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.308 | Q67 | What is the top-associated SNP of the gene PLEKHM1 in Whole Blood eQTL eQTLgen omic data for PSP and is it functionally significant? | The top-associated SNP for PLEKHM1 in Whole Blood eQTL eQTLgen omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 1.71e-22 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLEKHM1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1579413', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'PLEKHM1', 'p_SMR_multi': 1.705019e-22, 'p_HEIDI': 9.355808e-09, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1380 | Q67 | What is the top-associated SNP of the gene PLEKHM1 in Frontal Cortex BA9 eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for PLEKHM1 in Frontal Cortex BA9 eQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 2.27e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLEKHM1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1170868', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'PLEKHM1', 'p_SMR_multi': 2.267121e-07, 'p_HEIDI': 0.001124046, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1558 | Q67 | What is the top-associated SNP of the gene CCDC71 in Cerebellum eQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene CCDC71 in Cerebellum eQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CCDC71" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_23154', 'topRSID': 'rs11715581', 'Disease': 'PSP', 'Gene': 'CCDC71', 'p_SMR_multi': 0.1323887, 'p_HEIDI': 0.6038382, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1711982', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.317 | Q67 | What is the top-associated SNP of the gene KMT2E-AS1 in Whole Blood eQTL eQTLgen omic data for ALS and is it functionally significant? | There are no SNPs within the gene KMT2E-AS1 in Whole Blood eQTL eQTLgen omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KMT2E-AS1" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1511520', 'topRSID': 'rs193120021', 'Disease': 'ALS', 'Gene': 'KMT2E-AS1', 'p_SMR_multi': 0.7451824, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.152 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Anterior Cingulate Cortex BA24 eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Anterior Cingulate Cortex BA24 eQTL omic data for AD is rs199533, which has a multi-SNP SMR p-value of 2.10e-06 and a HEIDI of 0.88, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1480161', 'topRSID': 'rs199533', 'Disease': 'AD', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 2.101674e-06, 'p_HEIDI': 0.8771589, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1158 | Q67 | What is the top-associated SNP of the gene NUPL2 in Hypothalamus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for NUPL2 in Hypothalamus eQTL omic data for PD is rs2141307, which has a multi-SNP SMR p-value of 2.90e-06 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NUPL2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1461948', 'topRSID': 'rs2141307', 'Disease': 'PD', 'Gene': 'NUPL2', 'p_SMR_multi': 2.903356e-06, 'p_HEIDI': 0.01877344, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1223 | Q67 | What is the top-associated SNP of the gene GPC2 in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for GPC2 in Cerebellum eQTL omic data for AD is rs17309333, which has a multi-SNP SMR p-value of 8.86e-07 and a HEIDI of 0.27, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPC2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_272', 'topRSID': 'rs17309333', 'Disease': 'AD', 'Gene': 'GPC2', 'p_SMR_multi': 8.862247e-07, 'p_HEIDI': 0.2725038, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1687932', 'topRSID': '... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.580 | Q67 | What is the top-associated SNP of the gene LRRK2 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for LRRK2 in Whole Blood eQTL eQTLgen omic data for PD is rs4363681, which has a multi-SNP SMR p-value of 9.07e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRK2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1561430', 'topRSID': 'rs4363681', 'Disease': 'PD', 'Gene': 'LRRK2', 'p_SMR_multi': 9.070753e-07, 'p_HEIDI': 1.978415e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.51 | Q67 | What is the top-associated SNP of the gene CHRNE in Cortex eQTL GTEx omic data for AD and is it functionally significant? | The top-associated SNP for CHRNE in Cortex eQTL GTEx omic data for AD is rs72835069, which has a multi-SNP SMR p-value of 2.70e-06 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CHRNE" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1246971', 'topRSID': 'rs72835069', 'Disease': 'AD', 'Gene': 'CHRNE', 'p_SMR_multi': 2.702617e-06, 'p_HEIDI': 0.04331229, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1553 | Q67 | What is the top-associated SNP of the gene SCML4 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene SCML4 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SCML4" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_686896', 'topRSID': 'rs1546960', 'Disease': 'ALS', 'Gene': 'SCML4', 'p_SMR_multi': 0.2658353, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_686898', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.733 | Q67 | What is the top-associated SNP of the gene GDNF in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene GDNF in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GDNF" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_731591', 'topRSID': 'rs67720228', 'Disease': 'ALS', 'Gene': 'GDNF', 'p_SMR_multi': 0.009331988, 'p_HEIDI': 0.8116559, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_731588', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.840 | Q67 | What is the top-associated SNP of the gene CLU in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CLU in Whole Blood mQTL omic data for AD is rs9331888, which has a multi-SNP SMR p-value of 2.76e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CLU" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_615772', 'topRSID': 'rs9331888', 'Disease': 'AD', 'Gene': 'CLU', 'p_SMR_multi': 2.763826e-08, 'p_HEIDI': 6.190068e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1392 | Q67 | What is the top-associated SNP of the gene PRSS36 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PRSS36 in Whole Brain meta-analysis mQTL omic data for AD is rs78924645, which has a multi-SNP SMR p-value of 9.59e-07 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PRSS36" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_109538', 'topRSID': 'rs55667375', 'Disease': 'AD', 'Gene': 'PRSS36', 'p_SMR_multi': 6.457535e-07, 'p_HEIDI': 0.01582905, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1125 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Whole Blood eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Whole Blood eQTL GTEx omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 2.14e-15 and a HEIDI of 0.1, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1679563', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 2.139585e-15, 'p_HEIDI': 0.104475, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1176 | Q67 | What is the top-associated SNP of the gene HSD3B7 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for HSD3B7 in Whole Blood eQTL eQTLgen omic data for AD is rs4889606, which has a multi-SNP SMR p-value of 9.59e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HSD3B7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501472', 'topRSID': 'rs4889606', 'Disease': 'AD', 'Gene': 'HSD3B7', 'p_SMR_multi': 9.58512e-07, 'p_HEIDI': 0.004832233, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.476 | Q67 | What is the top-associated SNP of the gene C6orf10 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C6orf10 in Whole Blood mQTL omic data for AD is rs601945, which has a multi-SNP SMR p-value of 6.19e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C6orf10" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621662', 'topRSID': 'rs35265698', 'Disease': 'AD', 'Gene': 'C6orf10', 'p_SMR_multi': 2.929935e-08, 'p_HEIDI': 2.344082e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.980 | Q67 | What is the top-associated SNP of the gene KAT8 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for KAT8 in Whole Blood eQTL eQTLgen omic data for AD is rs1060506, which has a multi-SNP SMR p-value of 1.78e-07 and a HEIDI of 0.15, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KAT8" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501482', 'topRSID': 'rs1060506', 'Disease': 'AD', 'Gene': 'KAT8', 'p_SMR_multi': 1.783298e-07, 'p_HEIDI': 0.1463961, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.660 | Q67 | What is the top-associated SNP of the gene STAG3 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for STAG3 in Whole Brain meta-analysis mQTL omic data for AD is rs11767968, which has a multi-SNP SMR p-value of 1.42e-08 and a HEIDI of 0.09, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STAG3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_74050', 'topRSID': 'rs11767968', 'Disease': 'AD', 'Gene': 'STAG3', 'p_SMR_multi': 1.165779e-11, 'p_HEIDI': 8.480336e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.405 | Q67 | What is the top-associated SNP of the gene ARL17A in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Whole Blood eQTL eQTLgen omic data for PD is rs62074125, which has a multi-SNP SMR p-value of 5.25e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1564793', 'topRSID': 'rs62074125', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 5.250435e-11, 'p_HEIDI': 1.455558e-13, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.517 | Q67 | What is the top-associated SNP of the gene LRRC37A in Cerebellum eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A in Cerebellum eQTL omic data for PSP is rs7225002, which has a multi-SNP SMR p-value of 1.94e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_22218', 'topRSID': 'rs7225002', 'Disease': 'PSP', 'Gene': 'LRRC37A', 'p_SMR_multi': 8.469841e-21, 'p_HEIDI': 7.804429e-15, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.324 | Q67 | What is the top-associated SNP of the gene SFXN3 in Anterior Cingulate Cortex BA24 eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene SFXN3 in Anterior Cingulate Cortex BA24 eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SFXN3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1487579', 'topRSID': 'rs76529895', 'Disease': 'PD', 'Gene': 'SFXN3', 'p_SMR_multi': 0.899054, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.20 | Q67 | What is the top-associated SNP of the gene SNX31 in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for SNX31 in Cerebellum eQTL omic data for AD is rs1693551, which has a multi-SNP SMR p-value of 8.91e-07 and a HEIDI of 0.89, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNX31" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_3737', 'topRSID': 'rs1693568', 'Disease': 'AD', 'Gene': 'SNX31', 'p_SMR_multi': 4.685159e-07, 'p_HEIDI': 0.7160667, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1688163', 'topRSID': ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.691 | Q67 | What is the top-associated SNP of the gene TP53BP1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene TP53BP1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TP53BP1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_105245', 'topRSID': 'rs2253807', 'Disease': 'AD', 'Gene': 'TP53BP1', 'p_SMR_multi': 0.4557166, 'p_HEIDI': 0.9466071, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.36 | Q67 | What is the top-associated SNP of the gene CHST13 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | There are no SNPs within the gene CHST13 in Whole Blood eQTL eQTLgen omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CHST13" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1492963', 'topRSID': 'rs11718493', 'Disease': 'AD', 'Gene': 'CHST13', 'p_SMR_multi': 0.1263505, 'p_HEIDI': 0.9526882, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.910 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Prefrontal Cortex eQTL omic data for AD is rs2696466, which has a multi-SNP SMR p-value of 1.22e-08 and a HEIDI of 0.05, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203020', 'topRSID': 'rs2696466', 'Disease': 'AD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 1.220094e-08, 'p_HEIDI': 0.04836808, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.834 | Q67 | What is the top-associated SNP of the gene RP11-378J18.8 in Whole Brain eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene RP11-378J18.8 in Whole Brain eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-378J18.8" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1612924', 'topRSID': 'rs17465982', 'Disease': 'ALS', 'Gene': 'RP11-378J18.8', 'p_SMR_multi': 0.284868, 'p_HEIDI': 0.9618152, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1798 | Q67 | What is the top-associated SNP of the gene NSFP1 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for NSFP1 in Whole Blood eQTL eQTLgen omic data for PD is rs17698176, which has a multi-SNP SMR p-value of 9.33e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NSFP1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1564791', 'topRSID': 'rs17698176', 'Disease': 'PD', 'Gene': 'NSFP1', 'p_SMR_multi': 9.333059e-10, 'p_HEIDI': 5.118198e-11, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.413 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Amygdala eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A2 in Amygdala eQTL omic data for PSP is rs393152, which has a multi-SNP SMR p-value of 1.65e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1604719', 'topRSID': 'rs393152', 'Disease': 'PSP', 'Gene': 'LRRC37A2', 'p_SMR_multi': 1.654495e-15, 'p_HEIDI': 2.312915e-17, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.928 | Q67 | What is the top-associated SNP of the gene CTD-2516F10.2 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene CTD-2516F10.2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTD-2516F10.2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_465896', 'topRSID': 'rs7949121', 'Disease': 'PD', 'Gene': 'CTD-2516F10.2', 'p_SMR_multi': 0.004017807, 'p_HEIDI': 0.1142147, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_upda... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.543 | Q67 | What is the top-associated SNP of the gene PLD2 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for PLD2 in Whole Blood eQTL eQTLgen omic data for AD is rs2286670, which has a multi-SNP SMR p-value of 5.05e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLD2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501909', 'topRSID': 'rs2286670', 'Disease': 'AD', 'Gene': 'PLD2', 'p_SMR_multi': 5.045019e-08, 'p_HEIDI': 0.004146128, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.765 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Whole Brain meta-analysis mQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.54e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560854', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 1.544458e-18, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1905 | Q67 | What is the top-associated SNP of the gene GAK in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for GAK in Whole Blood mQTL omic data for PD is rs6837528, which has a multi-SNP SMR p-value of 6.03e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GAK" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996273', 'topRSID': 'rs12651271', 'Disease': 'PD', 'Gene': 'GAK', 'p_SMR_multi': 6.180527e-09, 'p_HEIDI': 3.619298e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1071 | Q67 | What is the top-associated SNP of the gene CTB-171A8.1 in Whole Brain eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CTB-171A8.1 in Whole Brain eQTL omic data for AD is rs61744497, which has a multi-SNP SMR p-value of 1.42e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTB-171A8.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1611533', 'topRSID': 'rs61744497', 'Disease': 'AD', 'Gene': 'CTB-171A8.1', 'p_SMR_multi': 1.420057e-11, 'p_HEIDI': 5.845447e-08, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1209 | Q67 | What is the top-associated SNP of the gene TRAPPC6A in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for TRAPPC6A in Cortex eQTL metaBrain omic data for AD is rs12462040, which has a multi-SNP SMR p-value of 7.03e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TRAPPC6A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1108036', 'topRSID': 'rs12462040', 'Disease': 'AD', 'Gene': 'TRAPPC6A', 'p_SMR_multi': 7.034371e-07, 'p_HEIDI': 0.0006778446, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.248 | Q67 | What is the top-associated SNP of the gene ARL17B in Nucleus Accumbens Basal Ganglia omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17B in Nucleus Accumbens Basal Ganglia omic data for PSP is rs4792831, which has a multi-SNP SMR p-value of 4.35e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17B" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1732399', 'topRSID': 'rs4792831', 'Disease': 'PSP', 'Gene': 'ARL17B', 'p_SMR_multi': 4.354531e-07, 'p_HEIDI': 5.579067e-08, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance threshold but shows s... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1431 | Q67 | What is the top-associated SNP of the gene TMEM180 in Whole Blood mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene TMEM180 in Whole Blood mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM180" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_768577', 'topRSID': 'rs4919643', 'Disease': 'FTD', 'Gene': 'TMEM180', 'p_SMR_multi': 0.1711406, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_768576', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1137 | Q67 | What is the top-associated SNP of the gene APOC2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOC2 in Whole Blood mQTL omic data for AD is rs12460352, which has a multi-SNP SMR p-value of 1.99e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_637437', 'topRSID': 'rs5120', 'Disease': 'AD', 'Gene': 'APOC2', 'p_SMR_multi': 1.276397e-24, 'p_HEIDI': 2.572368e-19, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.791 | Q67 | What is the top-associated SNP of the gene CLUHP3 in Whole Blood eQTL eQTLgen omic data for ALS and is it functionally significant? | There are no SNPs within the gene CLUHP3 in Whole Blood eQTL eQTLgen omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CLUHP3" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1517159', 'topRSID': 'rs4632148', 'Disease': 'ALS', 'Gene': 'CLUHP3', 'p_SMR_multi': 0.5680645, 'p_HEIDI': 0.756811, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1744 | Q67 | What is the top-associated SNP of the gene SLC39A13 in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for SLC39A13 in Cortex eQTL metaBrain omic data for AD is rs2071304, which has a multi-SNP SMR p-value of 2.19e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SLC39A13" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1112424', 'topRSID': 'rs2071304', 'Disease': 'AD', 'Gene': 'SLC39A13', 'p_SMR_multi': 2.194578e-06, 'p_HEIDI': 0.005743233, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.495 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Whole Brain eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Whole Brain eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 5.46e-41 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1646044', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 5.463693999999998e-41, 'p_HEIDI': 2.645557e-08, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.157 | Q67 | What is the top-associated SNP of the gene DND1P1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for DND1P1 in Whole Blood mQTL omic data for PD is rs199447, which has a multi-SNP SMR p-value of 4.93e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948856', 'topRSID': 'rs199447', 'Disease': 'PD', 'Gene': 'DND1P1', 'p_SMR_multi': 4.92908e-15, 'p_HEIDI': 3.866787e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.970 | Q67 | What is the top-associated SNP of the gene TSC22D4 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for TSC22D4 in Whole Blood eQTL eQTLgen omic data for AD is rs3807471, which has a multi-SNP SMR p-value of 2.43e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TSC22D4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495812', 'topRSID': 'rs3807471', 'Disease': 'AD', 'Gene': 'TSC22D4', 'p_SMR_multi': 2.429445e-08, 'p_HEIDI': 0.0002477143, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.