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A 46-year-old man with hypertension and dyslipidemia diagnosed 4-months before, as well as new-onset diabetes mellitus unveiled 1-month earlier, was referred to emergency department for hypokalemia. | [
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Hormonal study and dynamic biochemical tests performed indicated ECS. | [
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Imaging and cytological findings pointed toward a likely primary right parotid malignancy with liver metastases. | [
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Somatostatin receptor scintigraphy has shown an increased uptake in the parotid gland and mild expression in liver metastasis. | [
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The patient underwent right parotidectomy, and histopathologic examination confirmed ACC. | [
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Meanwhile, hypercortisolism was managed with metyrapone, ketoconazole, and lanreotide. | [
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Despite chemotherapy onset, a rapid disease progression and clinical course deterioration was observed. | [
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We present a case of a 32-year-old woman with a history of gradual enlargement of the anterior neck. | [
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The medical history was unremarkable and no comorbidities existed. | [
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There was no history of radiation exposure. | [
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Clinical examination revealed a multinodular goiter. | [
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Computed tomography showed a thyroid nodule of the lef... | EN100310 |
Computed tomography showed a thyroid nodule of the left lobe extended to the isthmus and the right lobe with anterior and posterior capsular rupture contracting close contact with the vascular axis left carotid-jugular plunging into the cervicothoracic away from the hole aortic arch. | [
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There was no evidence of lung lesions. | [
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The patient underwent a surgical exploration. | [
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There was a hard left lobe nodule of 5 cm infiltrating the adjacent muscles and partially infiltrates the trachea. | [
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The intraoperative consultation pathology diagnosis was: undifferentiated carcinoma. | [
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A total thyroidectomy was realized. | [
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Histological examination showed a proliferation of elongated spindle-shaped cells, arranged in interweaving fascicles of varying sizes, intersected at right angles. | [
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Chromatin is distributed inhomogeneously. | [] | We present a case of a 32-year-old woman with a history of gradual enlargement of the anterior neck. The medical history was unremarkable and no comorbidities existed. There was no history of radiation exposure. Clinical examination revealed a multinodular goiter.
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The tumor realize a pushing against thyroid parenchyma which is separated with a fibrous capsule. | [
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Computed tomography showed a thyroid nodule of the lef... | EN100310 |
The mitotic rate was extremely high (19 mitosis/10 high power field), and atypical mitotic figures were also present. | [
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Computed tomography showed a thyroid nodule of the lef... | EN100310 |
The neoplasia showed invasion of the peri-glandular fat tissue. | [
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Computed tomography showed a thyroid nodule of the lef... | EN100310 |
Immuno-histochemical staining of the slides with caldesmon, desmin, PanCK, CK5-6, CK7, myogenin, epithelial membrane antigen (EMA), CEA, thyroid transcription factor (TTF-1), pancytokeratin, smooth muscle actin (SMA), MelanA, S 100 protein, CD 45, CD3, CD30, CD 20, CD 15, CD34, ALK, calcitonin and KI 67 protein was per... | [
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The tumour was strongly positive for caldesmon, SMA, desmin, and negative for pancytokeratin and other epithelial, lymphoid and melanocytic markers. | [
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On the basis of the clinical, radiographic, histopathological and immunohistochemical features, the final diagnosis was primary thyroid leiomyosarcoma, FNCLCC grade 3. | [
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Computed tomography showed a thyroid nodule of the lef... | EN100310 |
In multidisciplinary tumour board, it was decided that adjuvant loco regional RT and chemotherapy by ifosfamide and doxorubicin. | [
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Computed tomography showed a thyroid nodule of the lef... | EN100310 |
A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. | [
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She was born from a full-term and uncomplicated pregnancy during which the mother had no prenatal ultrasound (US). | [
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Clinical findings: on physical examination, she was colored and active. | [
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Her vitals were within normal limits as well as her anthropometric parameters (weight: 10kg). | [
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Abdomen was soft on palpation and tympanic on percussion. | [
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... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
The digital rectal examination was unremarkable. | [
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"text": "examination",
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"role": "",
"semantic_type_id": "",
"text": "unremarkable",
"type": "RML"
... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Symptomatic treatment was initiated with lactulose (five mL bid) and an antispasmodic, trimebutine (five mL bid). | [
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12,
21
],
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"text": "initiated",
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... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Timeline: our patient experienced first symptoms since August 2019. | [
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"id": "7873",
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48
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"role": "",
"semantic_type_id": "",
"text": "symptoms",
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10,
21
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"role": "PATIENT",
"semantic_type_id": "",
"text": "our patient",
"type": "ACTO... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Parents brought her at our service only on 27 th July 2020 two days after they remarked visible peristalsis on her abdominal wall. | [
{
"id": "7888",
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8,
15
],
"role": "",
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"text": "brought",
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{
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"text": "remarked",
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{
... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
The patient has been treated and discharged in August 2020 and pathology results were available 11 days later. | [
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"role": "",
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... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Diagnostic assessment: blood results were within normal range. | [
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21
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"text": "assessment",
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{
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36
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... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Abdominal X-ray showed distension of an intestinal loop in the left lumbar region. | [
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15
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"role": "",
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"text": "X-ray",
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22
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"text": "showed",
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{
... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Abdominal US identified a misleading colonic dilatation containing heterogeny echoic substance, with no other additional features. | [
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12
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"text": "identified",
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{
... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Contrast enema was unremarkable. | [
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9,
14
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"role": "",
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"text": "enema",
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31
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"role": "",
"semantic_type_id": "",
"text": "unremarkable",
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}
] | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Due to financial constraints, upper gastro-intestinal (GI) series and abdominal computed tomography (CT) could not be performed. | [
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17,
28
],
"role": "",
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"text": "constraints",
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},
{
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59,
65
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"role": "",
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"text": "series",
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},
... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
An exploratory laparotomy has been indicated with presumptive diagnosis of intestinal duplication. | [
{
"id": "8218",
"offsets": [
15,
25
],
"role": "",
"semantic_type_id": "",
"text": "laparotomy",
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},
{
"id": "8233",
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35,
44
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"role": "",
"semantic_type_id": "",
"text": "indicated",
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},... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Therapeutic intervention: after the median laparotomy, a dilatated segment of the jejunum was identified at approximately ten cm from the Treitz's angle. | [
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12,
24
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"role": "",
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"text": "intervention",
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"text": "laparotomy",
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... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Its diameter was fourfold greater than of the adjacent bowel, to which the dilatation was connected abruptly, without any identified obstructive cause. | [
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"id": "8308",
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4,
12
],
"role": "",
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"text": "diameter",
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},
{
"id": "8323",
"offsets": [
75,
85
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"role": "",
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"text": "dilatation",
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},
... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
It measured ten cm in length and had prominent serosal vessels. | [
{
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3,
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],
"role": "",
"semantic_type_id": "",
"text": "measured",
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{
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"offsets": [
37,
62
],
"role": "",
"semantic_type_id": "",
"text": "prominent serosal vessels",
"type":... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Adjacent mesentery was thickened. | [
{
"id": "8383",
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23,
32
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"role": "",
"semantic_type_id": "",
"text": "thickened",
"type": "EVENT"
},
{
"id": "8800",
"offsets": [
9,
18
],
"role": "",
"semantic_type_id": "C0266235",
"text": "mesentery",
"type": "CLINE... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
No further anatomic anomaly was identified. | [
{
"id": "8398",
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20,
27
],
"role": "",
"semantic_type_id": "",
"text": "anomaly",
"type": "EVENT"
},
{
"id": "8413",
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32,
42
],
"role": "",
"semantic_type_id": "",
"text": "identified",
"type": "EVENT"
}
] | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
A resection of the dilatated portion was performed, followed by end-to-end jejunal anastomosis using Vicryl 3/0 in separate stitches. | [
{
"id": "8428",
"offsets": [
2,
11
],
"role": "",
"semantic_type_id": "",
"text": "resection",
"type": "EVENT"
},
{
"id": "8443",
"offsets": [
83,
94
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"role": "",
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"text": "anastomosis",
"type": "EVENT"
}
... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Follow-up and outcomes: microscopic examination revealed a lymphocytic infiltration of both layers of the muscularis propria. | [
{
"id": "8458",
"offsets": [
0,
9
],
"role": "",
"semantic_type_id": "",
"text": "Follow-up",
"type": "EVENT"
},
{
"id": "8473",
"offsets": [
14,
22
],
"role": "",
"semantic_type_id": "",
"text": "outcomes",
"type": "EVENT"
},
{... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
The dense lymphocytic infiltration was mainly constituted of T lymphocytes CD3+/8+ (C and D) and some B lymphocytes CD20+. | [
{
"id": "8533",
"offsets": [
22,
34
],
"role": "",
"semantic_type_id": "",
"text": "infiltration",
"type": "EVENT"
},
{
"id": "8814",
"offsets": [
10,
34
],
"role": "",
"semantic_type_id": "C1262091",
"text": "lymphocytic infiltration",... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Locally diminished actin coloration indicated atrophy of smooth muscle fibers. | [
{
"id": "8548",
"offsets": [
25,
35
],
"role": "",
"semantic_type_id": "",
"text": "coloration",
"type": "EVENT"
},
{
"id": "8563",
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36,
45
],
"role": "",
"semantic_type_id": "",
"text": "indicated",
"type": "EVENT"
},... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Nerve fibers and ganglion cells of myenteric and submucosal plexuses were intact with focalized absence of NK CD56+ cells around lymphocytic infiltration. | [
{
"id": "8593",
"offsets": [
74,
80
],
"role": "",
"semantic_type_id": "",
"text": "intact",
"type": "EVENT"
},
{
"id": "8828",
"offsets": [
129,
153
],
"role": "",
"semantic_type_id": "C1262091",
"text": "lymphocytic infiltration",
... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
No ectopic tissue was identified. | [
{
"id": "8608",
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11,
17
],
"role": "",
"semantic_type_id": "",
"text": "tissue",
"type": "EVENT"
},
{
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"offsets": [
22,
32
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"role": "",
"semantic_type_id": "",
"text": "identified",
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}
] | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
The postoperative period was uneventful. | [
{
"id": "8638",
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29,
39
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"role": "",
"semantic_type_id": "",
"text": "uneventful",
"type": "EVENT"
},
{
"id": "9170",
"offsets": [
4,
17
],
"role": "",
"semantic_type_id": "",
"text": "postoperative",
"type": "TIMEX3"
... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
The patient was on parenteral nutrition until day seven postoperatively. | [
{
"id": "8653",
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30,
39
],
"role": "",
"semantic_type_id": "",
"text": "nutrition",
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{
"id": "9054",
"offsets": [
0,
11
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"role": "PATIENT",
"semantic_type_id": "",
"text": "The patient",
"type": "ACTO... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
She was discharged on day ten and after three months of monthly follow-up, colicky abdominal pain and chronic constipation had disappeared since the early postoperative days. | [
{
"id": "8668",
"offsets": [
8,
18
],
"role": "",
"semantic_type_id": "",
"text": "discharged",
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},
{
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64,
73
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"role": "",
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"text": "follow-up",
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},
... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
For the future, the follow-up will be done on a three months basis for a year and then, twice yearly. | [
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"id": "8743",
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20,
29
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"role": "",
"semantic_type_id": "",
"text": "follow-up",
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{
"id": "9233",
"offsets": [
46,
66
],
"role": "",
"semantic_type_id": "",
"text": "a three months basis",
"type": "T... | A 17 months girl have been consulted in our service for colicky abdominal pain often associated with constipation and loss of appetite, since she was six months old. Parents kept her at home until they remarked visible peristalsis on the abdominal wall, which lead them to consult our service. She was born from a full-t... | EN100700 |
Here we report a case of aggressive metastatic cholangiocarcinoma (MCC) in 72-year-old man, sequentially treated with two targeted chemotherapies. | [
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"text": "report",
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{
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"text": "cholangiocarcinoma",
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... | Here we report a case of aggressive metastatic cholangiocarcinoma (MCC) in 72-year-old man, sequentially treated with two targeted chemotherapies. Initially disease quickly progressed during best clinical practice care (gemcitabine in combination with cisplatin or capecitabine), which was accompanied by significant dec... | EN103220 |
Initially disease quickly progressed during best clinical practice care (gemcitabine in combination with cisplatin or capecitabine), which was accompanied by significant decrease of life quality. | [
{
"id": "2768",
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10,
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"role": "",
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"text": "disease",
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{
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26,
36
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"role": "",
"semantic_type_id": "",
"text": "progressed",
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... | Here we report a case of aggressive metastatic cholangiocarcinoma (MCC) in 72-year-old man, sequentially treated with two targeted chemotherapies. Initially disease quickly progressed during best clinical practice care (gemcitabine in combination with cisplatin or capecitabine), which was accompanied by significant dec... | EN103220 |
Monotherapy with TKI sorafenib was prescribed to the patient, which resulted in stabilization of tumor growth and elimination of pain. | [
{
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0,
11
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"role": "",
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"text": "Monotherapy",
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45
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"role": "",
"semantic_type_id": "",
"text": "prescribed",
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}... | Here we report a case of aggressive metastatic cholangiocarcinoma (MCC) in 72-year-old man, sequentially treated with two targeted chemotherapies. Initially disease quickly progressed during best clinical practice care (gemcitabine in combination with cisplatin or capecitabine), which was accompanied by significant dec... | EN103220 |
The choice of the inhibitor was made based on high-throughput screening of gene expression in the patient's tumor biopsy, utilized by Oncobox platform to build a personalized rating of potentially effective target therapies. | [
{
"id": "2933",
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"text": "choice",
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37,
42
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"text": "based",
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{
... | Here we report a case of aggressive metastatic cholangiocarcinoma (MCC) in 72-year-old man, sequentially treated with two targeted chemotherapies. Initially disease quickly progressed during best clinical practice care (gemcitabine in combination with cisplatin or capecitabine), which was accompanied by significant dec... | EN103220 |
However, time to progression after start of sorafenib administration did not exceed 6 months and the regimen was changed to monotherapy with Pazopanib, another TKI predicted to be effective for this patient according to the same molecular test. | [
{
"id": "3023",
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"text": "progression",
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{
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35,
40
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"role": "",
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"text": "start",
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... | Here we report a case of aggressive metastatic cholangiocarcinoma (MCC) in 72-year-old man, sequentially treated with two targeted chemotherapies. Initially disease quickly progressed during best clinical practice care (gemcitabine in combination with cisplatin or capecitabine), which was accompanied by significant dec... | EN103220 |
It resulted in disease progression according to RECIST with simultaneous elimination of sorafenib side effects such as rash and hand-foot syndrome. | [
{
"id": "3143",
"offsets": [
23,
34
],
"role": "",
"semantic_type_id": "",
"text": "progression",
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},
{
"id": "3158",
"offsets": [
73,
84
],
"role": "",
"semantic_type_id": "",
"text": "elimination",
"type": "EVENT"
... | Here we report a case of aggressive metastatic cholangiocarcinoma (MCC) in 72-year-old man, sequentially treated with two targeted chemotherapies. Initially disease quickly progressed during best clinical practice care (gemcitabine in combination with cisplatin or capecitabine), which was accompanied by significant dec... | EN103220 |
After 2 years from the diagnosis of MCC the patient was alive and physically active, which is substantially longer than median survival for standard therapy. | [
{
"id": "3203",
"offsets": [
36,
39
],
"role": "",
"semantic_type_id": "",
"text": "MCC",
"type": "EVENT"
},
{
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56,
61
],
"role": "",
"semantic_type_id": "",
"text": "alive",
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},
{
"i... | Here we report a case of aggressive metastatic cholangiocarcinoma (MCC) in 72-year-old man, sequentially treated with two targeted chemotherapies. Initially disease quickly progressed during best clinical practice care (gemcitabine in combination with cisplatin or capecitabine), which was accompanied by significant dec... | EN103220 |
A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. | [
{
"id": "6759",
"offsets": [
22,
34
],
"role": "",
"semantic_type_id": "",
"text": "hypertensive",
"type": "EVENT"
},
{
"id": "6774",
"offsets": [
36,
48
],
"role": "",
"semantic_type_id": "",
"text": "hospitalized",
"type": "EVENT"... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
In the family history, her mother, sisters and cousins underwent a surgery for MNG. | [
{
"id": "6789",
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14,
21
],
"role": "",
"semantic_type_id": "",
"text": "history",
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},
{
"id": "6804",
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74
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"role": "",
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"text": "surgery",
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},
{
... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, laryngeal, vascular or neurologic signs. | [
{
"id": "6834",
"offsets": [
59,
68
],
"role": "",
"semantic_type_id": "",
"text": "described",
"type": "EVENT"
},
{
"id": "6849",
"offsets": [
87,
98
],
"role": "",
"semantic_type_id": "",
"text": "compression",
"type": "EVENT"
}... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
She never suffered from thyroid dysfunction. | [
{
"id": "6924",
"offsets": [
10,
18
],
"role": "",
"semantic_type_id": "",
"text": "suffered",
"type": "EVENT"
},
{
"id": "6939",
"offsets": [
32,
43
],
"role": "",
"semantic_type_id": "",
"text": "dysfunction",
"type": "EVENT"
},... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
Her neck was deformed by the voluminous formation classified grade III according to the WHO modified classification. | [
{
"id": "6954",
"offsets": [
13,
21
],
"role": "",
"semantic_type_id": "",
"text": "deformed",
"type": "EVENT"
},
{
"id": "7832",
"offsets": [
4,
8
],
"role": "",
"semantic_type_id": "",
"text": "neck",
"type": "BODYPART"
}
] | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
The mass took the front and the two sides of the neck. | [
{
"id": "7736",
"offsets": [
4,
8
],
"role": "",
"semantic_type_id": "C0149736",
"text": "mass",
"type": "CLINENTITY"
},
{
"id": "7838",
"offsets": [
14,
23
],
"role": "",
"semantic_type_id": "",
"text": "the front",
"type": "BODYPA... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
Its surface was embossed and covered by a thin normal skin. | [
{
"id": "6969",
"offsets": [
16,
24
],
"role": "",
"semantic_type_id": "",
"text": "embossed",
"type": "EVENT"
},
{
"id": "6984",
"offsets": [
29,
36
],
"role": "",
"semantic_type_id": "",
"text": "covered",
"type": "EVENT"
},
{... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
There were some veins of the collateral circulation limited to the neck. | [
{
"id": "7856",
"offsets": [
16,
51
],
"role": "",
"semantic_type_id": "",
"text": "veins of the collateral circulation",
"type": "BODYPART"
},
{
"id": "7862",
"offsets": [
63,
71
],
"role": "",
"semantic_type_id": "",
"text": "the neck... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
The goiter measured 18 x 11 cm. | [
{
"id": "6999",
"offsets": [
11,
19
],
"role": "",
"semantic_type_id": "",
"text": "measured",
"type": "EVENT"
},
{
"id": "7868",
"offsets": [
0,
10
],
"role": "",
"semantic_type_id": "",
"text": "The goiter",
"type": "BODYPART"
}... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
The mass was firm, painless, and mobile with the swallowing movements. | [
{
"id": "7743",
"offsets": [
4,
8
],
"role": "",
"semantic_type_id": "C0149736",
"text": "mass",
"type": "CLINENTITY"
}
] | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
Lymphadenopathy research was difficult and found no palpable lymph nodes. | [
{
"id": "7014",
"offsets": [
16,
24
],
"role": "",
"semantic_type_id": "",
"text": "research",
"type": "EVENT"
},
{
"id": "7029",
"offsets": [
43,
48
],
"role": "",
"semantic_type_id": "",
"text": "found",
"type": "EVENT"
},
{
... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
The laboratory tests (T 3, T 4 and TSH) were normal. | [
{
"id": "7059",
"offsets": [
15,
20
],
"role": "",
"semantic_type_id": "",
"text": "tests",
"type": "EVENT"
}
] | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
Thoracic radiography showed a large cervical opacity roughly round and strewn with microcalcifications associated with a right eccentricity of the trachea. | [
{
"id": "7074",
"offsets": [
9,
20
],
"role": "",
"semantic_type_id": "",
"text": "radiography",
"type": "EVENT"
},
{
"id": "7089",
"offsets": [
21,
27
],
"role": "",
"semantic_type_id": "",
"text": "showed",
"type": "EVENT"
},
... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
Cervical and chest CT revealed the presence of a partially calcified thyroid mass slightly plunging in the anterior mediastinum. | [
{
"id": "7119",
"offsets": [
19,
21
],
"role": "",
"semantic_type_id": "",
"text": "CT",
"type": "EVENT"
},
{
"id": "7134",
"offsets": [
22,
30
],
"role": "",
"semantic_type_id": "",
"text": "revealed",
"type": "EVENT"
},
{
... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
It took heterogeneously the contrast and then evocate a large MNG. | [
{
"id": "7771",
"offsets": [
62,
65
],
"role": "",
"semantic_type_id": "",
"text": "MNG",
"type": "CLINENTITY"
}
] | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
The trachea was surrounded by the goiter, slightly narrowed and right deviated as well as the lower part of the larynx. | [
{
"id": "7164",
"offsets": [
16,
26
],
"role": "",
"semantic_type_id": "",
"text": "surrounded",
"type": "EVENT"
},
{
"id": "7179",
"offsets": [
70,
78
],
"role": "",
"semantic_type_id": "",
"text": "deviated",
"type": "EVENT"
},
... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
The right and left vascular axes of the neck (carotid artery and jugular vein) were deviated backward. | [
{
"id": "7194",
"offsets": [
84,
92
],
"role": "",
"semantic_type_id": "",
"text": "deviated",
"type": "EVENT"
},
{
"id": "7916",
"offsets": [
0,
44
],
"role": "",
"semantic_type_id": "",
"text": "The right and left vascular axes of the... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
The patient underwent a surgery for her enormous MNG slightly plunging in the mediastinum. | [
{
"id": "7209",
"offsets": [
24,
31
],
"role": "",
"semantic_type_id": "",
"text": "surgery",
"type": "EVENT"
},
{
"id": "7778",
"offsets": [
49,
52
],
"role": "",
"semantic_type_id": "",
"text": "MNG",
"type": "CLINENTITY"
},
{... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
Endotracheal intubation was relatively easy by the laryngoscope. | [
{
"id": "7224",
"offsets": [
13,
23
],
"role": "",
"semantic_type_id": "",
"text": "intubation",
"type": "EVENT"
}
] | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
The incision performed was a Kocher cervicotomy. | [
{
"id": "7239",
"offsets": [
4,
12
],
"role": "",
"semantic_type_id": "",
"text": "incision",
"type": "EVENT"
}
] | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
There was a multinodular, hypervascularized goiter. | [
{
"id": "7934",
"offsets": [
44,
50
],
"role": "",
"semantic_type_id": "",
"text": "goiter",
"type": "BODYPART"
}
] | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
Its lower end plunges behind the sternal manubrium. | [] | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
The larynx was deviated towards the right side. | [
{
"id": "7254",
"offsets": [
15,
23
],
"role": "",
"semantic_type_id": "",
"text": "deviated",
"type": "EVENT"
},
{
"id": "7940",
"offsets": [
0,
10
],
"role": "",
"semantic_type_id": "",
"text": "The larynx",
"type": "BODYPART"
}... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
The total thyroidectomy was performed in two steps: initially a right lobo-isthmectomy, then the left lobectomy. | [
{
"id": "7269",
"offsets": [
10,
23
],
"role": "",
"semantic_type_id": "",
"text": "thyroidectomy",
"type": "EVENT"
},
{
"id": "7284",
"offsets": [
70,
86
],
"role": "",
"semantic_type_id": "",
"text": "lobo-isthmectomy",
"type": "E... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
The retrosternal part of the goiter was released using the finger by the same incision. | [
{
"id": "7314",
"offsets": [
40,
48
],
"role": "",
"semantic_type_id": "",
"text": "released",
"type": "EVENT"
},
{
"id": "7952",
"offsets": [
0,
35
],
"role": "",
"semantic_type_id": "",
"text": "The retrosternal part of the goiter",
... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
Both recurrent laryngeal nerves (RLN) were not identified because of the hemorrhage. | [
{
"id": "7329",
"offsets": [
47,
57
],
"role": "",
"semantic_type_id": "",
"text": "identified",
"type": "EVENT"
},
{
"id": "7344",
"offsets": [
73,
83
],
"role": "",
"semantic_type_id": "",
"text": "hemorrhage",
"type": "EVENT"
}... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
One parathyroid gland was accidently devascularized and was autotransplanted to the ipsilateral sternocleidomastoid muscle. | [
{
"id": "7359",
"offsets": [
37,
51
],
"role": "",
"semantic_type_id": "",
"text": "devascularized",
"type": "EVENT"
},
{
"id": "7374",
"offsets": [
60,
76
],
"role": "",
"semantic_type_id": "",
"text": "autotransplanted",
"type": "... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
The operation was finished by double aspiration drainage. | [
{
"id": "7389",
"offsets": [
4,
13
],
"role": "",
"semantic_type_id": "",
"text": "operation",
"type": "EVENT"
},
{
"id": "7404",
"offsets": [
18,
26
],
"role": "",
"semantic_type_id": "",
"text": "finished",
"type": "EVENT"
}
] | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
In the first hours after surgery, the patient developed a large cervical hematoma. | [
{
"id": "7419",
"offsets": [
46,
55
],
"role": "",
"semantic_type_id": "",
"text": "developed",
"type": "EVENT"
},
{
"id": "7792",
"offsets": [
73,
81
],
"role": "",
"semantic_type_id": "C0018944",
"text": "hematoma",
"type": "CLINE... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
She was readmitted to the operating room, and after evacuation of the hematoma there was no vessels bleeding. | [
{
"id": "7434",
"offsets": [
8,
18
],
"role": "",
"semantic_type_id": "",
"text": "readmitted",
"type": "EVENT"
},
{
"id": "7449",
"offsets": [
52,
62
],
"role": "",
"semantic_type_id": "",
"text": "evacuation",
"type": "EVENT"
},... | A 50-years-old woman, hypertensive, hospitalized for a large cervical mass appeared 30 years ago. In the family history, her mother, sisters and cousins underwent a surgery for MNG. Despite of the large volume of the mass, the patient never described signs of cervical compression whatsoever respiratory, digestive, lary... | EN100067 |
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