The full dataset viewer is not available (click to read why). Only showing a preview of the rows.
The dataset generation failed because of a cast error
Error code:   DatasetGenerationCastError
Exception:    DatasetGenerationCastError
Message:      An error occurred while generating the dataset

All the data files must have the same columns, but at some point there are 10 new columns ({'mutant_rank', 'mut_Rank_Stab', 'mut_netchop_score_ct', 'mutant_rank_PRIME', 'mutant_other_significant_alleles', 'mutant_seq', 'seq_len', 'TAP_score', 'mutant_rank_netMHCpan', 'wt_seq'}) and 31 missing columns ({'HLA', 'anchor_mutation', 'pubmed_id', 'genomic_coord', 'mt_peptide', 'netmhcpan_rank', 'tumor_type_detail', 'netmhcstabpan_stability', 'length', 'effector_origin', 'wt_peptide', 'assay_type', 'dai_netmhcpan', 'bigmhc_im_score', 'mutation_type', 'presentation_method', 'ndd_id', 'reference_name', 'ref', 'eluted_ligand_match', 'position', 'tcga_cancer_expression_tpm_median', 'mutation', 'alt', 'prime_rank', 'driver_status', 'chromosome', 'tap_score', 'stimulation_target', 'tumor_tissue', 'netchop_score'}).

This happened while the csv dataset builder was generating data using

hf://datasets/NeoDiscovery/NDD/data/leaderboard/nip_leaderboard_train.tsv (at revision f4d033289b4846e6a9bc50efd5ed847e438bdd2e)

Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)
Traceback:    Traceback (most recent call last):
                File "/usr/local/lib/python3.12/site-packages/datasets/builder.py", line 1831, in _prepare_split_single
                  writer.write_table(table)
                File "/usr/local/lib/python3.12/site-packages/datasets/arrow_writer.py", line 714, in write_table
                  pa_table = table_cast(pa_table, self._schema)
                             ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
                File "/usr/local/lib/python3.12/site-packages/datasets/table.py", line 2272, in table_cast
                  return cast_table_to_schema(table, schema)
                         ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
                File "/usr/local/lib/python3.12/site-packages/datasets/table.py", line 2218, in cast_table_to_schema
                  raise CastError(
              datasets.table.CastError: Couldn't cast
              patient_id: string
              response_type: string
              gene: string
              mutant_seq: string
              wt_seq: string
              seq_len: int64
              mutant_rank_netMHCpan: double
              mutant_rank: double
              mutant_other_significant_alleles: int64
              mutant_rank_PRIME: double
              TAP_score: double
              mut_Rank_Stab: double
              mut_netchop_score_ct: double
              -- schema metadata --
              pandas: '{"index_columns": [{"kind": "range", "name": null, "start": 0, "' + 1909
              to
              {'ndd_id': Value('string'), 'patient_id': Value('string'), 'tumor_tissue': Value('string'), 'tumor_type_detail': Value('string'), 'gene': Value('string'), 'mutation_type': Value('string'), 'mutation': Value('string'), 'position': Value('string'), 'mt_peptide': Value('string'), 'wt_peptide': Value('string'), 'length': Value('int64'), 'chromosome': Value('string'), 'genomic_coord': Value('string'), 'ref': Value('string'), 'alt': Value('string'), 'HLA': Value('string'), 'response_type': Value('string'), 'assay_type': Value('string'), 'effector_origin': Value('string'), 'stimulation_target': Value('string'), 'presentation_method': Value('string'), 'netmhcpan_rank': Value('float64'), 'netmhcstabpan_stability': Value('float64'), 'prime_rank': Value('float64'), 'bigmhc_im_score': Value('float64'), 'tap_score': Value('float64'), 'netchop_score': Value('float64'), 'dai_netmhcpan': Value('float64'), 'anchor_mutation': Value('string'), 'eluted_ligand_match': Value('int64'), 'tcga_cancer_expression_tpm_median': Value('float64'), 'driver_status': Value('string'), 'pubmed_id': Value('string'), 'reference_name': Value('string')}
              because column names don't match
              
              During handling of the above exception, another exception occurred:
              
              Traceback (most recent call last):
                File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1455, in compute_config_parquet_and_info_response
                  parquet_operations = convert_to_parquet(builder)
                                       ^^^^^^^^^^^^^^^^^^^^^^^^^^^
                File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1054, in convert_to_parquet
                  builder.download_and_prepare(
                File "/usr/local/lib/python3.12/site-packages/datasets/builder.py", line 894, in download_and_prepare
                  self._download_and_prepare(
                File "/usr/local/lib/python3.12/site-packages/datasets/builder.py", line 970, in _download_and_prepare
                  self._prepare_split(split_generator, **prepare_split_kwargs)
                File "/usr/local/lib/python3.12/site-packages/datasets/builder.py", line 1702, in _prepare_split
                  for job_id, done, content in self._prepare_split_single(
                                               ^^^^^^^^^^^^^^^^^^^^^^^^^^^
                File "/usr/local/lib/python3.12/site-packages/datasets/builder.py", line 1833, in _prepare_split_single
                  raise DatasetGenerationCastError.from_cast_error(
              datasets.exceptions.DatasetGenerationCastError: An error occurred while generating the dataset
              
              All the data files must have the same columns, but at some point there are 10 new columns ({'mutant_rank', 'mut_Rank_Stab', 'mut_netchop_score_ct', 'mutant_rank_PRIME', 'mutant_other_significant_alleles', 'mutant_seq', 'seq_len', 'TAP_score', 'mutant_rank_netMHCpan', 'wt_seq'}) and 31 missing columns ({'HLA', 'anchor_mutation', 'pubmed_id', 'genomic_coord', 'mt_peptide', 'netmhcpan_rank', 'tumor_type_detail', 'netmhcstabpan_stability', 'length', 'effector_origin', 'wt_peptide', 'assay_type', 'dai_netmhcpan', 'bigmhc_im_score', 'mutation_type', 'presentation_method', 'ndd_id', 'reference_name', 'ref', 'eluted_ligand_match', 'position', 'tcga_cancer_expression_tpm_median', 'mutation', 'alt', 'prime_rank', 'driver_status', 'chromosome', 'tap_score', 'stimulation_target', 'tumor_tissue', 'netchop_score'}).
              
              This happened while the csv dataset builder was generating data using
              
              hf://datasets/NeoDiscovery/NDD/data/leaderboard/nip_leaderboard_train.tsv (at revision f4d033289b4846e6a9bc50efd5ed847e438bdd2e)
              
              Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)

Need help to make the dataset viewer work? Make sure to review how to configure the dataset viewer, and open a discussion for direct support.

ndd_id
string
patient_id
string
tumor_tissue
string
tumor_type_detail
string
gene
string
mutation_type
string
mutation
string
position
string
mt_peptide
string
wt_peptide
string
length
int64
chromosome
string
genomic_coord
string
ref
string
alt
string
HLA
string
response_type
string
assay_type
string
effector_origin
string
stimulation_target
string
presentation_method
string
netmhcpan_rank
float64
netmhcstabpan_stability
float64
prime_rank
float64
bigmhc_im_score
float64
tap_score
float64
netchop_score
float64
dai_netmhcpan
float64
anchor_mutation
string
eluted_ligand_match
int64
tcga_cancer_expression_tpm_median
float64
driver_status
string
pubmed_id
string
reference_name
string
NDDR-8Y7QQTRFWC-U
GEXOATK7
Skin
Skin Cutaneous Melanoma
WDR46
SNV
p.T227I
3
FLIYLDVSV
FLTYLDVSV
9
6
33287207
G
A
HLA-A02:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC, tumor_cells
none
0.123
0.17
0.124
0.500021
0.2
0.152263
-0.198451
no
1
5.306263
null
PMID:33303615
Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer
NDDR-2HJHFX0EFJ-0
GEXOATK7
Skin
Skin Cutaneous Melanoma
AHNAK
SNV
p.S4460F
1
FMPDFDLHL
SMPDFDLHL
9
11
62526678
G
A
HLA-A02:01
CD8
ELISPOT, ICS, multimer
patient_TIL
peptide_pulsed_APC
none
0.057
0.3
0.053
0.582847
0.782
0.978539
-0.816761
no
1
4.897806
Other Tumor Driver
PMID:33303615
Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer
NDDR-M2GXDWKP1W-D
ZWHDI5GT
Skin
Skin Cutaneous Melanoma
GNB5
SNV
p.P377L
9
RVSTLRVSL
RVSTLRVSP
9
15
52124519
G
A
HLA-B07:02
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.139
0.8
0.088
0.476441
1.286
0.034531
-3.435379
no
0
0.389732
null
PMID:33303615
Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer
NDDR-JRGCAYDCQA-S
6FHDB5EK
Skin
Skin Cutaneous Melanoma
TRAPPC1
SNV
p.R129G
4
FRSGLDSYV
FRSRLDSYV
9
17
7930659
G
C
HLA-C06:02
CD8
51Cr, HLA-block
patient_Tc_line
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
0.1
29
0.018
0.380201
0.366
0.73499
-0.41871
no
1
5.942411
null
PMID:10582700
Two antigens recognized by autologous cytolytic T lymphocytes on a Melanoma result from a single point mutation
NDDR-VXMQ2DHCNY-F
DAXCBTFA
Skin
Skin Cutaneous Melanoma
TRAPPC1
SNV
p.R129G
7
SELFRSGLDSY
SELFRSRLDSY
11
17
7930659
G
C
HLA-B44:02
CD8
51Cr, HLA-block
patient_Tc_line
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
0.266
0.4
0.581
0.052169
3.04
0.763436
0.158546
no
1
5.942411
null
PMID:10582700
Two antigens recognized by autologous cytolytic T lymphocytes on a Melanoma result from a single point mutation
NDDR-AHCH9CD88T-A
M4HZA63S
Skin
Skin Cutaneous Melanoma
HERV-K-MEL
SNV
p.V102I
5
MLAVISCAV
MLAVVSCAV
9
null
null
null
null
HLA-A02:01
CD8
51Cr, HLA-block
patient_Tc_line
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
1.022
0.3
0.553
0.416587
0.378
null
-0.068993
no
0
null
null
PMID:12359761
A human endogenous retroviral sequence encoding an antigen recognized on Melanoma by cytolytic T lymphocytes
NDDR-MG2GYB7FKK-1
LFXUCEDT
Skin
Skin Cutaneous Melanoma
PRDX5
SNV
p.S79L
6
LLLDDLLVSI
LLLDDSLVSI
10
11
64321032
C
T
HLA-A02:01
CD8
51Cr, HLA-block, multimer
patient_Tc_line, patient_TIL
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
0.171
0.4
0.046
0.535931
0.624
0.954141
0.047913
no
1
7.68365
null
PMID:15695408
Immunogenicity without immunoselection: a mutant but functional antioxidant enzyme retained in a human metastatic Melanoma and targeted by CD8(+) T cells with a memory phenotype
NDDR-3Q45K91QR4-F
D35NTCNS
Skin
Skin Cutaneous Melanoma
MYO1B
SNV
p.E911K
1
KINKNPKYK
EINKNPKYK
9
2
191414079
G
A
HLA-A03:01
CD8
51Cr, HLA-block, multimer
patient_Tc_line, patient_TIL
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
0.024
0.2
0.013
0.446357
0.552
0.634706
-4.044512
no
1
3.642422
null
PMID:10064075
A natural cytotoxic T cell response in a spontaneously regressing human Melanoma targets a neoantigen resulting from a somatic point mutation
NDDR-7SABVDNYFG-Y
TSXDFNM6
Head & Neck
Head and Neck Squamous Cell Carcinoma
TP53
SNV
p.Y220C
4
VVPCEPPEV
VVPYEPPEV
9
null
null
null
null
HLA-A02:01
CD8
51Cr, HLA-block
patient_Tc_line
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
0.751
9
1.073
0.317315
0.454
0.687508
0.629941
no
1
3.293914
Tumor Driver
PMID:17294448
Immunological characterization of missense mutations occurring within cytotoxic T cell defined p53 epitopes in HLA A0201 squamous cell carcinomas of the head and neck
NDDR-GSSA542C57-I
7LJZLSYK
Skin
Skin Cutaneous Melanoma
ENTPD4
SNV
p.P85L
7
ATDTNNLNVNY
ATDTNNPNVNY
11
8
23447838
G
A
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
none
2.391
4.5
1.282
0.364496
2.864
0.96242
0.671223
no
0
3.119629
null
PMID:33038342
Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction
NDDR-SGEY1B756Q-7
7LJZLSYK
Skin
Skin Cutaneous Melanoma
TTC37
SNV
p.A692V
6
YLDGKVVDY
YLDGKAVDY
9
5
95520755
G
A
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
none
3.937
35
11.33
0.307559
2.426
null
-0.116625
no
0
3.005436
null
PMID:33038342
Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction
NDDR-WSV1MDSJB6-H
TFT6DO6A
Skin
Skin Cutaneous Melanoma
ARMT1
SNV
p.P286L
2
FYGKTILWF
FPGKTILWF
9
6
151468641
C
T
HLA-A24:02
CD8
ELISPOT, ICS, multimer
PBMC_postVax
peptide_pulsed_APC
none
0.052
0.25
0.02
0.351818
2.108
null
-4.193145
no
0
2.896756
null
PMID:30880120
Identification of a neoantigen epitope in a Melanoma patient with good response to anti-PD-1 antibody therapy
NDDR-XMMWH86R9X-E
FNWFEVPE
Cerebellum/Posterior fossa
Medulloblastoma (pediatric)
PDCD10
SNV
p.A74P
4
IASPIKEL
IASAIKEL
8
3
167687680
C
G
HLA-C12:02
CD8
ELISPOT, ICS, multimer
patient_Tc_line, PBMC_pre
peptide_pulsed_APC
none
0.234
2.5
3.957
0.149582
0.99
0.48951
-1.082819
no
0
null
null
PMID:31351799
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy
NDDR-BBEYF3X3HN-4
FNWFEVPE
Cerebellum/Posterior fossa
Medulloblastoma (pediatric)
PDCD10
SNV
p.A74P
10
LQTIKDIASPI
LQTIKDIASAI
11
3
167687680
C
G
HLA-B52:01
CD8
ELISPOT, ICS, multimer
patient_Tc_line, PBMC_pre
peptide_pulsed_APC
none
7.046
0.4
10.695
0.000387
0.728
0.897295
0.649004
no
0
null
null
PMID:31351799
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy
NDDR-8FNTWKZDFG-Y
FU5SPZUA
Cerebellum/Posterior fossa
Medulloblastoma (pediatric)
TSEN54
SNV
p.R472Q
2
AQMCISGF
ARMCISGF
8
17
75523764
G
A
HLA-C12:03
CD8
ELISPOT, ICS, multimer
patient_Tc_line, PBMC_pre
peptide_pulsed_APC
none
22.864
1.2
33.066
0.003008
3.142
0.307014
-0.193672
yes
0
null
null
PMID:31351799
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy
NDDR-JDQYDNJXFT-A
FU5SPZUA
Cerebellum/Posterior fossa
Medulloblastoma (pediatric)
PCSK9
SNV
p.V202F
11
DHREIEGRVMF
DHREIEGRVMV
11
1
55052358
G
T
HLA-B18:01
CD8
ELISPOT, ICS, multimer
patient_Tc_line, PBMC_pre
peptide_pulsed_APC
none
0.158
12
1.548
0.145635
2.264
0.536006
-2.522178
no
0
null
null
PMID:31351799
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy
NDDR-0J9XF0AJTT-A
FU5SPZUA
Cerebellum/Posterior fossa
Medulloblastoma (pediatric)
PCSK9
SNV
p.V202F
1
FTDFENVP
VTDFENVP
8
1
55052358
G
T
HLA-C05:01
CD8
ELISPOT, ICS, multimer
patient_Tc_line, PBMC_pre
peptide_pulsed_APC
none
9.493
45
8.173
0.146671
-0.474
0.405231
-0.296779
no
0
null
null
PMID:31351799
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy
NDDR-0V67NT0BT2-D
FU5SPZUA
Cerebellum/Posterior fossa
Medulloblastoma (pediatric)
NEU2
SNV
p.L234T
9
KTGEQRVVTL
KTGEQRVVLL
10
2
233034587
G
A
HLA-C12:03
CD8
ELISPOT, ICS, multimer
patient_Tc_line, PBMC_pre
peptide_pulsed_APC
none
9.571
5.5
5.727
0.004257
0.814
null
-0.381034
yes
0
null
null
PMID:31351799
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy
NDDR-9A9KVDPVGD-V
FU5SPZUA
Cerebellum/Posterior fossa
Medulloblastoma (pediatric)
SVIL
SNV
p.D1285N
8
RTDVKAYNVT
RTDVKAYDVT
10
null
null
null
null
HLA-C05:01
CD8
ELISPOT, ICS, multimer
patient_Tc_line, PBMC_pre
peptide_pulsed_APC
none
12.052
31
3.575
0.175771
-0.81
0.027018
-0.39557
no
0
null
null
PMID:31351799
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy
NDDR-NB93YAHBJ0-B
4V2JUJEQ
Liver
Hepatocellular Carcinoma
C5orf42
SNV
p.I1134K
13
DADILSETFQLLK
DADILSETFQLLI
13
5
37201697
A
T
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre, patient_Tc_line
peptide_pulsed_APC
none
12.983
5.5
2.664
0.158422
null
null
-1.87901
no
0
null
null
PMID:31887370
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
NDDR-1YAP0FVN2C-U
4V2JUJEQ
Liver
Hepatocellular Carcinoma
C5orf42
SNV
p.I1134K
11
DILSETFQLLK
DILSETFQLLI
11
5
37201697
A
T
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre, patient_Tc_line
peptide_pulsed_APC
none
3.101
1.8
0.978
0.09474
0.296
null
-2.96262
no
0
null
null
PMID:31887370
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
NDDR-0T85G4PK4N-4
4V2JUJEQ
Liver
Hepatocellular Carcinoma
C5orf42
SNV
p.I1134K
10
ILSETFQLLK
ILSETFQLLI
10
5
37201697
A
T
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre, patient_Tc_line
peptide_pulsed_APC
none
0.675
0.5
0.762
0.072464
0.432
null
-3.858778
no
0
null
null
PMID:31887370
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
NDDR-JPW6QH0ZNW-D
4V2JUJEQ
Liver
Hepatocellular Carcinoma
C5orf42
SNV
p.I1134K
9
LSETFQLLK
LSETFQLLI
9
5
37201697
A
T
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre, patient_Tc_line
peptide_pulsed_APC
none
0.544
1.2
0.28
0.121928
0.316
null
-3.752958
no
0
null
null
PMID:31887370
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
NDDR-NPWGNEDF13-E
G4ZPYEDM
Skin
Skin Cutaneous Melanoma
DDX3X
SNV
p.E388K
4
FPKKIQMLA
FPKEIQMLA
9
X
41345316
G
A
HLA-B56:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.006
0.07
0.347
0.831153
-1.374
0.920179
0.405465
no
0
4.161428
Tumor Driver
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-1RZ65VX580-B
G4ZPYEDM
Skin
Skin Cutaneous Melanoma
ITGA9
SNV
p.L548P
7
VTEKLQPTY
VTEKLQLTY
9
3
37542539
T
C
HLA-A01:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.02
0.12
0.02
0.281449
2.714
0.946856
1.609438
no
0
1.3091
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-5NDTKW9WVC-U
G6DBM54G
Skin
Skin Cutaneous Melanoma
VPS16
SNV
p.S404F
5
LRAAFFGKCF
LRAASFGKCF
10
20
2862814
C
T
HLA-B27:05
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
2.327
0.8
0.612
0.411294
2.934
0.412664
-0.018732
no
0
3.703167
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-MHSQEBMGSW-D
G6DBM54G
Skin
Skin Cutaneous Melanoma
CIT
SNV
p.P2056L
4
VRTLLSQVNK
VRTPLSQVNK
10
12
119690296
G
A
HLA-B27:05
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.829
0.4
1.059
0.659847
0.756
0.817271
0.578183
no
0
0.65081
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-M431P5K4KM-3
G6DBM54G
Skin
Skin Cutaneous Melanoma
CASP1
SNV
p.P172S
8
WRNILLLSLH
WRNILLLPLH
10
11
105041480
G
A
HLA-B27:05
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
2.113
1.2
0.462
0.79588
-0.566
null
-0.025235
no
0
2.91849
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-YZD3GSV3PV-C
F3XRZQLP
Skin
Skin Cutaneous Melanoma
FAM200A
SNV
p.S116F
9
IPLSDNTIF
IPLSDNTIS
9
7
99548061
G
A
HLA-B35:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.049
0.12
0.039
0.542263
1.964
0.042772
-4.541121
yes
0
1.976985
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-QFKBAJAWPA-S
F3XRZQLP
Skin
Skin Cutaneous Melanoma
GRIN2B
SNV
p.E1104K
5
REFDKIELAY
REFDEIELAY
10
12
13563928
C
T
HLA-B41:02
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.527
2.5
0.137
0.473416
3.384
0.977014
-0.564753
no
0
-7.861448
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-3FYD6RDVNQ-7
F3XRZQLP
Skin
Skin Cutaneous Melanoma
TBX4
SNV
p.S271F
5
YPVIFKSIM
YPVISKSIM
9
17
61480110
C
T
HLA-B35:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.083
0.08
0.076
0.853465
-0.268
0.949069
0.170345
yes
0
-5.357024
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-J3PXJHBAC2-D
URSBQAUG
Skin
Skin Cutaneous Melanoma
FAM50B
SNV
p.E78K
7
DMKARQKALV
DMKARQEALV
10
6
3850043
G
A
HLA-B08:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.843
3
3.24
0.65091
0.1
0.521495
0.064934
yes
0
2.637761
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-BGT2WPZEN8-J
F3XRZQLP
Skin
Skin Cutaneous Melanoma
COL22A1
SNV
p.D291N
7
FPQGLPNEY
FPQGLPDEY
9
8
138826756
C
T
HLA-B35:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
none
0.003
0.09
0.016
0.566362
2.026
0.818258
0
yes
0
0.919263
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-51YCQP8A9M-3
F3XRZQLP
Skin
Skin Cutaneous Melanoma
COL22A1
SNV
p.D291N
3
LPNEYAFVTT
LPDEYAFVTT
10
8
138826756
C
T
HLA-B35:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
4.521
1
0.237
0.364148
-1.422
0.05056
0.028721
yes
0
0.919263
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-B7GMHB69XA-S
F3XRZQLP
Skin
Skin Cutaneous Melanoma
COL22A1
SNV
p.D291N
3
LPNEYAFVT
LPDEYAFVT
9
8
138826756
C
T
HLA-B35:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.923
0.5
0.19
0.718165
-1.422
0.499
-0.327767
yes
0
0.919263
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-2YDKRK2AD9-K
NGE5BUYC
Skin
Skin Cutaneous Melanoma
TTBK2
SNV
p.S1088L
9
RPHHDQRSL
RPHHDQRSS
9
15
42745988
G
A
HLA-B07:02
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.008
0.05
0.1
0.729896
0.654
0.118015
-4.77702
no
0
0.111698
null
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-VAPV22ZYG6-H
LC3W5VRX
Skin
Skin Cutaneous Melanoma
KIF26B
SNV
p.N256S
2
SSYTGFANK
SNYTGFANK
9
1
245367135
A
G
HLA-A11:01
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.007
0.3
0.006
0.334228
0.99
0.970843
-4.330733
no
0
1.124709
null
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-KWE7NJQDW7-I
LYXKV47S
Skin
Skin Cutaneous Melanoma
SPOP
SNV
p.N147I
7
FLLDEAIGL
FLLDEANGL
9
17
49619021
T
A
HLA-A02:01
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.009
0.8
0.042
0.644657
0.738
0.943178
-0.893818
no
1
2.900451
Other Tumor Driver
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-KYVW6EZ6RX-E
OKQRI23E
Skin
Skin Cutaneous Melanoma
NARFL
SNV
p.E62K
1
KSQREEVRR
ESQREEVRR
9
null
null
null
null
HLA-A31:01
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.411
1.3
0.683
0.025452
1.666
null
-2.183067
no
0
null
null
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-NFN8N8118Y-F
VU5HBL4S
Skin
Skin Cutaneous Melanoma
PPFIA4
SNV
p.S709N
4
MRMNQGVCC
MRMSQGVCC
9
1
203053848
G
A
HLA-B39:06
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.418
0.09
3.039
0.972498
0.486
0.033837
0.42601
no
0
-0.786497
null
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-73G4NR2F2Q-7
LYXKV47S
Skin
Skin Cutaneous Melanoma
CDK4
SNV
p.R24L
2
ALDPHSGHFV
ARDPHSGHFV
10
12
57751647
C
A
HLA-A02:01
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.085
1.2
0.065
0.469788
0.228
0.668099
-4.919637
no
1
4.89147
Tumor Driver
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-B1DKTHN336-H
5DJDBZPW
Skin
Skin Cutaneous Melanoma
SYTL4
SNV
p.S363F
6
GRIAFFLKY
GRIAFSLKY
9
X
100687163
G
A
HLA-B27:05
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
MS
0.009
0.4
0.001
0.914394
3.272
0.977758
0.117783
no
1
-2.573045
null
PMID:27869121
Direct identification of clinically relevant neoepitopes presented on native human Melanoma tissue by mass spectrometry
NDDR-VZ6AX01GXJ-0
5DJDBZPW
Skin
Skin Cutaneous Melanoma
NCAPG2
SNV
p.P333L
2
KLILWRGLK
KPILWRGLK
9
7
158680743
G
A
HLA-A03:01
CD8
ELISPOT
patient_TIL
peptide_pulsed_APC
MS
0.184
0.4
0.122
0.435756
0.762
0.861472
-3.519785
no
1
2.653482
null
PMID:27869121
Direct identification of clinically relevant neoepitopes presented on native human Melanoma tissue by mass spectrometry
NDDR-PBXJS7YJDT-A
5DJDBZPW
Skin
Skin Cutaneous Melanoma
AKAP6
SNV
p.M1482I
6
KLKLPIIMK
KLKLPMIMK
9
14
32822259
G
C
HLA-A03:01
CD8
ELISPOT
patient_TIL
peptide_pulsed_APC
MS
0.006
0.12
0.001
0.468706
0.62
0.968833
-0.154151
no
1
-0.385819
null
PMID:27869121
Direct identification of clinically relevant neoepitopes presented on native human Melanoma tissue by mass spectrometry
NDDR-WKQY9KFRV9-K
PKPFBJDF
Skin
Skin Cutaneous Melanoma
NOP16
SNV
p.P169L
9
SPGPVKLEL
SPGPVKLEP
9
5
176384171
G
A
HLA-B07:02
CD8
ELISPOT
patient_TIL
peptide_pulsed_APC
MS
0.011
0.7
0.028
0.235061
0.112
null
-4.500819
no
1
2.721895
null
PMID:27869121
Direct identification of clinically relevant neoepitopes presented on native human Melanoma tissue by mass spectrometry
NDDR-C98AVT8VA9-K
I4HS6WN2
Skin
Skin Cutaneous Melanoma
CSNK1A1
SNV
p.S27L
2
GLFGDIYLA
GSFGDIYLA
9
5
149550885_149550886
TC
CT
HLA-A02:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.052
1.5
0.046
0.590849
-0.414
0.312295
-4.006284
no
1
3.029707
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-FF8XNFEPVF-X
74LV6E74
Skin
Skin Cutaneous Melanoma
MATN2
SNV
p.E226K
1
KTLTSVFQK
ETLTSVFQK
9
8
97931486
G
A
HLA-A11:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.004
0.01
0.001
0.441139
0.686
0.926989
-3.102342
no
1
2.156137
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-894FCPT0FK-1
74LV6E74
Skin
Skin Cutaneous Melanoma
CDK12
SNV
p.E928K
5
CILGKLFTK
CILGELFTK
9
7
40063036
G
A
HLA-A11:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.279
1.1
0.021
0.14316
0.56
0.34099
-0.327213
no
1
2.569549
Tumor Driver
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-AYRXPFMZNE-W
74LV6E74
Skin
Skin Cutaneous Melanoma
CDK12
SNV
p.E928K
5
CILGKLFTKK
CILGELFTKK
10
7
40063036
G
A
HLA-A11:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
1.908
1.2
0.466
0.20399
0.56
0.794302
0.048869
no
0
2.569549
Tumor Driver
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-YRY5RYAEAT-A
I4HS6WN2
Skin
Skin Cutaneous Melanoma
CSNK1A1
SNV
p.S27L
2
GLFGDIYLAI
GSFGDIYLAI
10
5
149550885_149550886
TC
CT
HLA-A02:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.369
0.8
0.185
0.573459
0.656
0.921601
-3.064454
no
1
3.029707
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-EMJNAQ3KAZ-G
I4HS6WN2
Skin
Skin Cutaneous Melanoma
HAUS3
SNV
p.T160A
7
ILNAMIAKI
ILNAMITKI
9
4
2240469
T
C
HLA-A02:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.43
0.5
0.15
0.647834
0.322
0.879551
0.750579
no
1
0.52195
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-BGR5R73328-J
74LV6E74
Skin
Skin Cutaneous Melanoma
MATN2
SNV
p.E226K
1
KTLTSVFQKK
ETLTSVFQKK
10
8
97931486
G
A
HLA-A11:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.054
0.01
0.069
0.448778
0.686
0.963817
-2.580497
no
0
2.156137
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-545JRB33M5-G
J5PM7M2Y
Skin
Skin Cutaneous Melanoma
PLEKHM2
SNV
p.H1005Y
10
LTDDRLFTCY
LTDDRLFTCH
10
1
15732428
C
T
HLA-A01:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.009
0.01
0.006
0.695479
2.652
0.412145
-4.333653
no
0
5.051104
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-F477MEXVTB-T
I4HS6WN2
Skin
Skin Cutaneous Melanoma
GAS7
SNV
p.H225Y
9
SLADEAEVYL
SLADEAEVHL
10
17
9934186
G
A
HLA-A02:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.095
2.5
0.045
0.343229
1.054
0.969244
-0.408968
no
1
5.458259
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-1NGBH26P25-G
J5PM7M2Y
Skin
Skin Cutaneous Melanoma
PPP1R3B
SNV
p.P176H
5
YTDFHCQYV
YTDFPCQYV
9
8
9141125
G
T
HLA-A01:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.224
1.3
0.005
0.684944
-0.158
0.901694
-0.117783
no
1
2.600531
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-3397S1P89B-T
J5PM7M2Y
Skin
Skin Cutaneous Melanoma
PPP1R3B
SNV
p.P176H
5
YTDFHCQYVK
YTDFPCQYVK
10
8
9141125
G
T
HLA-A01:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
0.841
1.2
0.145
0.480959
-0.008
0.912707
0.144291
no
1
2.600531
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-4H8V6XSZ4F-X
6K4YGFNF
Skin
Skin Cutaneous Melanoma
KIF16B
SNV
p.L1009P
2
APARLERRHSA
ALARLERRHSA
11
20
16378976
A
G
HLA-B07:02
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.459
0.7
2.211
0.022523
-0.818
0.78183
-3.671241
no
0
1.905253
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-1C3G4QSC15-G
6K4YGFNF
Skin
Skin Cutaneous Melanoma
FLNA
SNV
p.R2049C
1
CVRVSGQGL
RVRVSGQGL
9
X
154353082
G
A
HLA-B07:02
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
1.384
1.8
0.386
0.063144
1.114
0.953143
2.305479
no
0
7.162795
Other Tumor Driver
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-WYJW76M06R-8
TOGZJCOT
Skin
Skin Cutaneous Melanoma
PDS5A
SNV
p.Y1000F;H1007Y
1,8
FVVPYMIYLL
YVVPYMIHLL
10
null
null
null
null
HLA-C03:03
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
4.104
4.5
0.127
0.088732
0.976
0.971609
1.044545
yes
0
3.19243
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-XJ3RMEC41A-S
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MAGEA6
SNV
p.E168K
1
KVDPIGHVY
EVDPIGHVY
9
X
152767149
C
T
HLA-A01:01
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.011
0.02
0.006
0.538203
2.85
0.975792
0.606136
no
0
2.919136
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-BS3218G751-C
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MAGEA6
SNV
p.E168K
1
KVDPIGHVYIF
EVDPIGHVYIF
11
null
null
null
null
HLA-C05:01
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.207
20
0.147
0.218765
2.46
0.972332
-1.486205
no
0
2.919136
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-YXV2AQ4573-E
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MAGEA6
SNV
p.E168K
3
LMKVDPIGHVY
LMEVDPIGHVY
11
null
null
null
null
HLA-B15:01
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.178
0.04
0.557
0.094909
3.084
0.975792
-1.548041
no
0
2.919136
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-0CQM64X89C-U
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MED13
SNV
p.P1691S
6
SVQIISCQY
SVQIIPCQY
9
null
null
null
null
HLA-A30:02
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.122
2.5
0.031
0.996467
3.044
0.965587
0.541341
no
0
2.53319
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-8V8HWA94GP-6
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MED13
SNV
p.P1691S
5
VQIISCQY
VQIIPCQY
8
17
61961773
G
A
HLA-A30:02
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
1.365
4
11.228
0.965486
3.326
0.965587
0.328301
no
0
2.53319
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-R8DTB8R876-H
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MED13
SNV
p.P1691S
5
VQIISCQY
VQIIPCQY
8
17
61961773
G
A
HLA-B15:01
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.34
0.12
0.377
0.395824
3.326
0.965587
0.102098
no
0
2.53319
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-NG120S2XBY-F
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MED13
SNV
p.P1691S
7
VSVQIISCQY
VSVQIIPCQY
10
null
null
null
null
HLA-A30:02
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.491
3.5
1.446
0.992012
3.218
0.965587
-0.085823
no
0
2.53319
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-HHJP6E4WJE-W
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MED13
SNV
p.P1691S
7
VSVQIISCQY
VSVQIIPCQY
10
null
null
null
null
HLA-A01:01
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.715
0.12
1.623
0.058955
3.218
0.965587
0.035591
no
0
2.53319
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-NATBNFYEAK-1
YQSS3IYL
Ovary
Ovarian Cancer
HS6ST1
SNV
p.S405I
4
DYMIHIIEKW
DYMSHIIEKW
10
2
128268184
C
A
HLA-A23:01
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
0.328
0.9
0.215
0.596565
0.846
0.959502
0.291755
no
0
4.582285
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-BHHDNDR6ZQ-7
VMHDDH4X
Ovary
Ovarian Cancer
COPG2
SNV
p.T37I
1
IPINPRRCL
TPINPRRCL
9
7
130666910
G
A
HLA-B07:02
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
0.025
0.06
0.434
0.808351
0.486
0.764573
0.083382
no
0
3.153886
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-RABCTRZ18B-T
TKJU56TT
Ovary
Ovarian Cancer
SEPT9
SNV
p.R289H
7
SILEQMHRK
SILEQMRRK
9
null
null
null
null
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
0.02
0.6
0.128
0.189973
0.682
null
-1.848455
no
1
null
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-81PF6HAJE6-H
Q2ITNIFI
Ovary
Ovarian Cancer
PDPN
SNV
p.G222C
3
FICAIIVVV
FIGAIIVVV
9
1
13614365
G
T
HLA-A02:01
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
1.217
0.4
0.024
0.68459
0.196
0.680153
0.893544
no
0
2.404058
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-WAWJVEYCNM-3
Q2ITNIFI
Ovary
Ovarian Cancer
KIR2DS4
SNV
p.I7S
1
SMACVGFFL
IMACVGFFL
9
null
null
null
null
HLA-A02:01
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
1.021
1.9
0.068
0.363276
1.164
0.623868
-0.075436
no
0
-5.058894
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-B9FTPHZX9N-4
GNQ75CJK
Ovary
Ovarian Cancer
USP47
SNV
p.V170L
5
TSDYLSQSY
TSDYVSQSY
9
11
11892058
G
C
HLA-A01:01
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
0.002
0.4
0.004
0.252534
2.636
0.971324
0
no
0
0.7376
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-8KVBFCA09D-V
4DKUZH62
Ovary
Ovarian Cancer
ODZ3
SNV
p.A2490V
9
GAQSWLWFV
GAQSWLWFA
9
4
182799720
C
T
HLA-A02:11
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
0.923
0.7
0.142
0.975253
0.216
null
-1.199847
yes
0
null
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-453FFPEY00-B
YG2NSK3U
Brain
Glioblastoma (GBM)
IDH1
SNV
p.R132H
10
GWVKPIIIGH
GWVKPIIIGR
10
2
208248388
C
T
HLA-B58:01
CD8
ICS
PBMC_postVax
peptide_pulsed_APC
none
29.107
49
20.4
0.019775
-0.336
0.868231
-0.230244
yes
0
5.024923
Tumor Driver
PMID:30733620
Actively personalized vaccination trial for newly diagnosed glioblastoma
NDDR-W3ZRQB9QB9-K
TBH3PNXF
Brain
Glioblastoma (GBM)
SLC44A2
SNV
p.L204M
4
ITDMVEGAKK
ITDLVEGAKK
10
null
null
null
null
HLA-A03:01
CD8
ICS
PBMC_postVax
peptide_pulsed_APC
none
2.002
2.5
1.811
0.177257
0.114
0.373603
-0.165362
no
0
5.43825
null
PMID:30733620
Actively personalized vaccination trial for newly diagnosed glioblastoma
NDDR-Q35B4A9CVQ-7
MYK5YWYV
Brain
Glioblastoma (GBM)
RFX1
SNV
p.T324M
2
YMQTASTSYY
YTQTASTSYY
10
null
null
null
null
HLA-A01:01
CD8
ICS
PBMC_postVax
peptide_pulsed_APC
none
0.332
1
0.059
0.130624
2.824
0.966927
2.221616
no
0
1.410422
null
PMID:30733620
Actively personalized vaccination trial for newly diagnosed glioblastoma
NDDR-0EZ996H7KA-S
MYK5YWYV
Brain
Glioblastoma (GBM)
EPHB3
SNV
p.R677W
7
YTERQRWDF
YTERQRRDF
9
null
null
null
null
HLA-A01:01
CD8
ICS
PBMC_postVax
peptide_pulsed_APC
none
0.615
5
0.469
0.021732
2.126
0.088796
-0.998957
no
0
2.61188
null
PMID:30733620
Actively personalized vaccination trial for newly diagnosed glioblastoma
NDDR-A9KQRJ0YTC-U
ZLZLTBFT
Brain
Glioblastoma (GBM)
NUCB1
SNV
p.V300M
8
RLRMREHMMK
RLRMREHVMK
10
null
null
null
null
HLA-A03:01
CD8
ICS
PBMC_postVax
peptide_pulsed_APC
none
0.167
0.15
0.361
0.359162
0.784
0.947325
-0.247982
no
0
5.924214
null
PMID:30733620
Actively personalized vaccination trial for newly diagnosed glioblastoma
NDDR-44QS1THAG3-E
F3UNKL3Y
Brain
Glioblastoma (GBM)
RBKS
SNV
p.T95A
7
KQNDISAEF
KQNDISTEF
9
null
null
null
null
HLA-B15:01
CD8
ICS
PBMC_postVax
peptide_pulsed_APC
none
0.004
0.02
0.002
0.295377
2.718
0.966161
0.287682
no
0
0.333136
null
PMID:30733620
Actively personalized vaccination trial for newly diagnosed glioblastoma
NDDR-6J2G3WKA08-J
GVYOONV4
Brain
Glioblastoma (GBM)
SLC9A6
SNV
p.N572I
10
SAWLFRMWYI
SAWLFRMWYN
10
null
null
null
null
HLA-A02:01
CD8
ICS
PBMC_postVax
peptide_pulsed_APC
none
13.515
6
1.186
0.176609
1.012
0.022848
-1.778226
no
0
2.120799
null
PMID:30733620
Actively personalized vaccination trial for newly diagnosed glioblastoma
NDDR-EDQDWAWTP4-F
PFMINZ56
Breast
Breast Cancer
ECPAS
SNV
p.S186F
10
MPYGYVLNEF
MPYGYVLNES
10
9
111437072_111437073
CA
TT
HLA-B35:01
CD8
ELISPOT, 4-1BB
patient_TIL, TCR_clone
peptide_pulsed_APC, TMC_minigene
TMC
0.056
0.05
0.018
0.478653
2.356
0.422068
-4.303582
yes
0
4.401606
null
PMID:29867227
Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer
NDDR-Y3TJTRGEMA-S
PFMINZ56
Breast
Breast Cancer
CADPS2
SNV
p.R1266H
8
TYDTVHRHL
TYDTVHRRL
9
7
122320259
C
T
HLA-C04:01
CD8
ELISPOT, 4-1BB
patient_TIL, TCR_clone
peptide_pulsed_APC, TMC_minigene
TMC
0.006
25
0.001
0.660042
0.732
0.958242
-0.287682
no
0
3.089786
null
PMID:29867227
Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer
NDDR-9MF2CZ9EEC-U
6TP4IBLE
Skin
Skin Cutaneous Melanoma
PORCN
SNV
p.H346Y
8
LLHGFSFYL
LLHGFSFHL
9
X
48515902
C
T
HLA-A02:01
CD8
multimer, 51Cr
PBMC_pre, PBMC_postVax, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.086
0.15
0.015
0.734435
1.068
0.977941
0.059898
no
1
1.886384
null
PMID:31685621
Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens
NDDR-7HFGTRT2KG-Y
6TP4IBLE
Skin
Skin Cutaneous Melanoma
AKAP9
SNV
p.L947F
5
RLSDFSEQL
RLSDLSEQL
9
7
92002801
C
T
HLA-A02:01
CD8
multimer, 51Cr
PBMC_pre, PBMC_postVax, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.024
0.4
0.069
0.499613
1.168
0.977036
-0.223144
no
1
2.055005
Other Tumor Driver
PMID:31685621
Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens
NDDR-R6WWVF6EQ6-H
6TP4IBLE
Skin
Skin Cutaneous Melanoma
RASAL2
SNV
p.P637S
4
IMSSSLFNL
IMSPSLFNL
9
1
178452552
C
T
HLA-A02:01
CD8
multimer
PBMC_pre, PBMC_postVax, patient_TIL
peptide_pulsed_APC
none
0.236
0.6
0.066
0.306679
1.032
0.969002
1.352958
no
1
1.331619
null
PMID:31685621
Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens
NDDR-108MYSE1VC-U
6TP4IBLE
Skin
Skin Cutaneous Melanoma
CDKN2A
SNV
p.P114L
2
LLVDLAEEL
LPVDLAEEL
9
9
21971018
G
A
HLA-A02:01
CD8
multimer
PBMC_pre, PBMC_postVax, patient_TIL
peptide_pulsed_APC
none
0.1
2.5
0.174
0.478684
1.164
0.957983
-4.712319
no
0
1.258459
Tumor Driver
PMID:31685621
Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens
NDDR-1G2Z2Z3NBX-E
6TP4IBLE
Skin
Skin Cutaneous Melanoma
PDE7B
SNV
p.G113R
1
RMWDFDIFL
GMWDFDIFL
9
6
136149105
G
A
HLA-A02:01
CD8
multimer
PBMC_pre, PBMC_postVax, patient_TIL
peptide_pulsed_APC
none
0.022
0.09
0.005
0.719792
1.63
0.968043
-0.127833
no
0
-1.260168
null
PMID:31685621
Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens
NDDR-SEA7CN1KAX-E
6TP4IBLE
Skin
Skin Cutaneous Melanoma
GCN1L1
SNV
p.P274L
6
SLLRSLENV
SLLRSPENV
9
12
120177464
G
A
HLA-A02:01
CD8
multimer, 51Cr
PBMC_pre, PBMC_postVax, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.06
0.4
0.081
0.546661
0.416
null
-0.559616
no
1
null
null
PMID:31685621
Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens
NDDR-EZBD3HKP1K-1
6TP4IBLE
Skin
Skin Cutaneous Melanoma
SOCS6
SNV
p.P134L
9
SLRSHHYSL
SLRSHHYSP
9
18
70325069
C
T
HLA-B08:01
CD8
multimer, 51Cr
PBMC_pre, PBMC_postVax, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.006
0.6
0.023
0.480798
1.118
0.409931
-5.372961
yes
1
3.067294
null
PMID:31685621
Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens
NDDR-5GDBWJVZ1H-Z
6TP4IBLE
Skin
Skin Cutaneous Melanoma
POGK
SNV
p.P46L
3
WVLALFDEV
WVPALFDEV
9
1
166846616
C
T
HLA-A02:01
CD8
multimer
PBMC_pre, PBMC_postVax, patient_TIL
peptide_pulsed_APC, TMC_minigene
none
3.02
4.5
0.733
0.347158
0.314
0.288239
-0.050995
no
0
3.56306
null
PMID:31685621
Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens
NDDR-T0AFTDJ9PD-V
6TP4IBLE
Skin
Skin Cutaneous Melanoma
ZDBF2
SNV
p.S2228L
3
YILKYSVFL
YISKYSVFL
9
2
206311211
C
T
HLA-A02:01
CD8
multimer, 51Cr
PBMC_pre, PBMC_postVax, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.193
0.5
0.027
0.61301
0.96
0.963955
-0.179728
no
1
-0.664534
null
PMID:31685621
Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens
NDDR-47041KC807-I
6TP4IBLE
Skin
Skin Cutaneous Melanoma
GAS7
SNV
p.S270F
1
FLGEAWAQV
SLGEAWAQV
9
17
9934242
G
A
HLA-A02:01
CD8
multimer
PBMC_pre, PBMC_postVax, patient_TIL
peptide_pulsed_APC
none
0.055
0.9
0.392
0.592199
-0.264
0.969671
-0.828949
no
0
5.458259
null
PMID:31685621
Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens
NDDR-JV00FYYZJR-8
6TP4IBLE
Skin
Skin Cutaneous Melanoma
PNPLA4
SNV
p.P100S
3
ILSPSAHEL
ILPPSAHEL
9
X
7921826
G
A
HLA-A02:01
CD8
multimer
PBMC_pre, PBMC_postVax, patient_TIL
peptide_pulsed_APC
none
0.024
1.4
0.196
0.431042
0.922
0.976745
-0.432864
no
0
2.462092
null
PMID:31685621
Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens
NDDR-N6NTA1JDTE-W
352WTYXA
Ovary
Ovarian Cancer
PPM1F
SNV
p.C259Y
7
FLAPLFLVLL
FLAPLFCVLL
10
5
88203038
T
G
HLA-A24:02
CD8
ELISPOT
PBMC_postVax, patient_TIL
peptide_pulsed_APC
none
8.36
3
1.457
0.027011
0.736
null
-0.252377
no
0
0.780394
null
PMID:32660279
Intranodal Administration of Neoantigen Peptide-loaded Dendritic Cell Vaccine Elicits Epitope-specific T Cell Responses and Clinical Effects in a Patient with Chemorefractory Ovarian Cancer with Malignant Ascites
NDDR-MCK2ZAJ8GQ-7
R7NU4BAT
Brain
Glioblastoma (GBM)
WDR63
SNV
p.T690M
8
FYNDIILMV
FYNDIILTV
9
1
85124208
C
T
HLA-C06:02
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
none
0.042
34
0.001
0.937943
0.026
null
0.518794
no
0
null
null
PMID:30906654
Detection of neoantigen-specific T cells following a personalized vaccine in a patient with glioblastoma
NDDR-S6DN480CYD-V
XD6MQQ3M
Ovary
Ovarian Cancer
SSC4D
SNV
p.D85Y
9
YGTGHILLY
YGTGHILLD
9
7
76397626
C
A
HLA-B35:01
CD8
4-1BB, ICS
PBMC_pre
peptide_pulsed_APC, tumor_cells
none
0.347
5
0.095
0.34794
2.496
0.067292
-5.180179
yes
0
1.241352
null
PMID:31069153
Neoantigens retention in patient derived xenograft models mediates autologous T cells activation in ovarian cancer
NDDR-VS85BXHK0E-W
XD6MQQ3M
Ovary
Ovarian Cancer
SSC4D
SNV
p.D85Y
9
YGTGHILLY
YGTGHILLD
9
7
76397626
C
A
HLA-C12:03
CD8
4-1BB, ICS
PBMC_pre
peptide_pulsed_APC, tumor_cells
none
0.117
18
0.008
0.062591
2.496
0.067292
-5.774366
yes
0
1.241352
null
PMID:31069153
Neoantigens retention in patient derived xenograft models mediates autologous T cells activation in ovarian cancer
NDDR-HR56JF3PKD-V
XD6MQQ3M
Ovary
Ovarian Cancer
NAV1
SNV
p.K349M
1
MAKAKAVAL
KAKAKAVAL
9
null
null
null
null
HLA-B35:01
CD8
4-1BB, ICS
PBMC_pre
peptide_pulsed_APC, tumor_cells
none
0.841
1.2
1.189
0.061466
1.048
0.941944
-1.781601
yes
0
0.481402
null
PMID:31069153
Neoantigens retention in patient derived xenograft models mediates autologous T cells activation in ovarian cancer
NDDR-C5YZS7EBSD-V
XD6MQQ3M
Ovary
Ovarian Cancer
TRO
SNV
p.S598C
5
SVGACGFSY
SVGASGFSY
9
X
54930991
C
G
HLA-B35:01
CD8
4-1BB, ICS
PBMC_pre
peptide_pulsed_APC, tumor_cells
none
1.793
2.5
0.289
0.02987
2.782
null
1.156591
yes
0
1.602932
null
PMID:31069153
Neoantigens retention in patient derived xenograft models mediates autologous T cells activation in ovarian cancer
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