id stringlengths 3 6 | query stringlengths 30 142 | target_ids listlengths 1 1 | scores listlengths 1 1 |
|---|---|---|---|
1_1 | latest monoclonal antibody treatments for lupus | [
"c17"
] | [
1
] |
1_2 | mechanism of action for belimumab in SLE treatment | [
"c17"
] | [
1
] |
1_3 | how does anifrolumab target the interferon pathway in lupus? | [
"c17"
] | [
1
] |
1_4 | shift from glucocorticoids to targeted therapies in lupus management | [
"c17"
] | [
1
] |
1_5 | future of personalized medicine in treating systemic lupus erythematosus | [
"c17"
] | [
1
] |
2_1 | How do long-acting injectable antipsychotics differ from oral medications in their pharmacokinetics? | [
"c15"
] | [
1
] |
2_2 | Benefits of injectable antipsychotics for schizophrenia relapse prevention | [
"c15"
] | [
1
] |
2_3 | Why is oral tolerability testing required before prescribing long-acting injectable antipsychotics? | [
"c15"
] | [
1
] |
2_4 | Pharmacological mechanism of depot release in injectable antipsychotic formulations | [
"c15"
] | [
1
] |
2_5 | Does the use of long-acting antipsychotic injections improve long-term prognosis for schizophrenia? | [
"c15"
] | [
1
] |
3_1 | How did the practice of vaccination originate? | [
"c27"
] | [
1
] |
3_2 | What role have vaccines played in improving global health and life expectancy? | [
"c27"
] | [
1
] |
3_3 | When was smallpox officially declared eradicated and how was it achieved? | [
"c27"
] | [
1
] |
3_4 | What is the basic scientific principle behind how vaccines train the immune system? | [
"c27"
] | [
1
] |
3_5 | What are the primary challenges facing global immunization programs today? | [
"c27"
] | [
1
] |
4_1 | how does cognitive behavioral therapy address generalized anxiety disorder | [
"c9"
] | [
1
] |
4_2 | what is cognitive restructuring in the context of treating anxiety | [
"c9"
] | [
1
] |
4_3 | how do behavioral experiments help reduce GAD symptoms | [
"c9"
] | [
1
] |
4_4 | techniques for managing physiological arousal in anxiety disorders | [
"c9"
] | [
1
] |
4_5 | why do therapists encourage exposure exercises for excessive worry | [
"c9"
] | [
1
] |
5_1 | What is the role of an Asthma Action Plan for students in a school setting? | [
"c26"
] | [
1
] |
5_2 | Are students generally permitted to self-carry rescue inhalers at school? | [
"c26"
] | [
1
] |
5_3 | What are the best practices for training teachers and coaches to identify pediatric asthma attacks? | [
"c26"
] | [
1
] |
5_4 | How can schools reduce environmental asthma triggers in the classroom? | [
"c26"
] | [
1
] |
5_5 | How should schools coordinate with families to manage care for asthmatic students? | [
"c26"
] | [
1
] |
6_1 | how does maternal diet influence long-term health of the child | [
"c14"
] | [
1
] |
6_2 | what does the developmental origins of health and disease hypothesis suggest about prenatal nutrition | [
"c14"
] | [
1
] |
6_3 | connection between prenatal nutrient scarcity and adult metabolic diseases | [
"c14"
] | [
1
] |
6_4 | essential micronutrients for fetal organogenesis and development | [
"c14"
] | [
1
] |
6_5 | can prenatal nutrition affect a child's future risk of chronic disease | [
"c14"
] | [
1
] |
7_1 | developmental delays in infants with congenital heart defects | [
"c8"
] | [
1
] |
7_2 | why do babies with CHD have trouble reaching motor milestones? | [
"c8"
] | [
1
] |
7_3 | impact of hospital stays and surgery on child development in CHD patients | [
"c8"
] | [
1
] |
7_4 | benefits of early intervention services for children with heart conditions | [
"c8"
] | [
1
] |
7_5 | do all children born with congenital heart defects experience developmental delays? | [
"c8"
] | [
1
] |
8_1 | benefits of integrating electronic health records for patient safety | [
"c10"
] | [
1
] |
8_2 | how does ehr interoperability help prevent medical errors | [
"c10"
] | [
1
] |
8_3 | role of clinical decision support in electronic health records | [
"c10"
] | [
1
] |
8_4 | how do integrated health records improve care transitions | [
"c10"
] | [
1
] |
8_5 | why are siloed health records a risk to patient safety | [
"c10"
] | [
1
] |
9_1 | What are the primary differences between mechanical and bioprosthetic heart valves? | [
"c18"
] | [
1
] |
9_2 | How do tissue-engineered heart valves differ from current prosthetic options? | [
"c18"
] | [
1
] |
9_3 | Why is Transcatheter Aortic Valve Replacement considered a significant advancement in cardiac care? | [
"c18"
] | [
1
] |
9_4 | What are the current limitations of traditional valve replacement devices? | [
"c18"
] | [
1
] |
9_5 | Can heart valve replacement avoid the need for long-term anticoagulation therapy? | [
"c18"
] | [
1
] |
10_1 | How does the hippocampus use synaptic plasticity to encode declarative memories? | [
"c4"
] | [
1
] |
10_2 | What is the role of the NMDA receptor as a coincidence detector in neurons? | [
"c4"
] | [
1
] |
10_3 | How does Long-Term Potentiation increase synaptic sensitivity to glutamate? | [
"c4"
] | [
1
] |
10_4 | What is the cellular difference between Long-Term Potentiation and Long-Term Depression? | [
"c4"
] | [
1
] |
10_5 | How does calcium influx lead to changes in AMPA receptor densit during memory formation? | [
"c4"
] | [
1
] |
11_1 | clinical management protocol for acute myocardial infarction | [
"c3"
] | [
1
] |
11_2 | door-to-balloon time goal for STEMI patients | [
"c3"
] | [
1
] |
11_3 | differentiating STEMI and NSTE-ACS in emergency settings | [
"c3"
] | [
1
] |
11_4 | reperfusion strategies for heart attack patients when PCI is not available | [
"c3"
] | [
1
] |
11_5 | initial emergency department assessment steps for suspected AMI | [
"c3"
] | [
1
] |
12_1 | Why do traditional SIR models struggle to accurately predict viral transmission in high-density urban environments? | [
"c11"
] | [
1
] |
12_2 | How do agent-based models and network analysis improve the accuracy of urban epidemic forecasting? | [
"c11"
] | [
1
] |
12_3 | What role does high-resolution mobility data play in identifying potential superspreading sites within cities? | [
"c11"
] | [
1
] |
12_4 | How do socioeconomic factors like housing density and labor type influence disease spread models? | [
"c11"
] | [
1
] |
12_5 | How can cities use granular epidemiological simulations to develop targeted non-pharmaceutical interventions? | [
"c11"
] | [
1
] |
13_1 | How have targeted therapies improved the outlook for HER2-positive breast cancer patients? | [
"c5"
] | [
1
] |
13_2 | What are biological missiles in the context of breast cancer treatment? | [
"c5"
] | [
1
] |
13_3 | Are there specific HER2 breast cancer drugs that can cross the blood-brain barrier? | [
"c5"
] | [
1
] |
13_4 | What is the mechanism of action for trastuzumab and pertuzumab in breast cancer? | [
"c5"
] | [
1
] |
13_5 | Difference between monoclonal antibodies and tyrosine kinase inhibitors for treating HER2-positive tumors | [
"c5"
] | [
1
] |
14_1 | How does the aging process affect lung structure and COPD progression in the elderly? | [
"c6"
] | [
1
] |
14_2 | What is the relationship between inflammaging and COPD in older populations? | [
"c6"
] | [
1
] |
14_3 | Why are elderly patients more susceptible to airway remodeling and bacterial colonization in COPD? | [
"c6"
] | [
1
] |
14_4 | Role of protease and anti-protease imbalance in geriatric COPD pathology | [
"c6"
] | [
1
] |
14_5 | Factors contributing to dyspnea and air trapping in elderly patients with COPD | [
"c6"
] | [
1
] |
15_1 | How has the scientific understanding of glial cells evolved from being considered passive support structures? | [
"c23"
] | [
1
] |
15_2 | Why do peripheral nerves regenerate more effectively than those in the central nervous system? | [
"c23"
] | [
1
] |
15_3 | What is the specific role of Schwann cells in the repair of peripheral nerves? | [
"c23"
] | [
1
] |
15_4 | Why does the glial scar created by astrocytes inhibit axonal regrowth in the CNS? | [
"c23"
] | [
1
] |
15_5 | Can modulating the activity of reactive astrocytes help with central nervous system injury recovery? | [
"c23"
] | [
1
] |
16_1 | how does chronic sleep deprivation impact cardiovascular health | [
"c21"
] | [
1
] |
16_2 | physiological mechanisms connecting sleep loss to high blood pressure | [
"c21"
] | [
1
] |
16_3 | link between sleep deficiency and systemic inflammation or atherosclerosis | [
"c21"
] | [
1
] |
16_4 | does lack of sleep increase risk of diabetes and heart disease | [
"c21"
] | [
1
] |
16_5 | why should sleep deprivation be considered a clinical determinant of heart disease | [
"c21"
] | [
1
] |
17_1 | How does the hypothalamic-pituitary-ovarian axis regulate the menstrual cycle? | [
"c24"
] | [
1
] |
17_2 | What role do FSH and LH play in ovulation and follicle development? | [
"c24"
] | [
1
] |
17_3 | How do conditions like PCOS impact hormonal feedback loops and fertility? | [
"c24"
] | [
1
] |
17_4 | Explain the hormonal changes that trigger menstruation if pregnancy doesn't occur. | [
"c24"
] | [
1
] |
17_5 | How do clinicians use hormone profiles to diagnose infertility issues? | [
"c24"
] | [
1
] |
18_1 | What is the primary function of the autonomic nervous system? | [
"c1"
] | [
1
] |
18_2 | How do the sympathetic and parasympathetic nervous systems differ in their functions? | [
"c1"
] | [
1
] |
18_3 | Explain the role of the autonomic nervous system in maintaining body homeostasis | [
"c1"
] | [
1
] |
18_4 | How does the autonomic nervous system automatically regulate heart rate and temperature? | [
"c1"
] | [
1
] |
18_5 | What role does the autonomic nervous system play in the fight-or-flight response? | [
"c1"
] | [
1
] |
19_1 | How does the gut microbiome influence immune system development? | [
"c19"
] | [
1
] |
19_2 | What are the effects of microbial dysbiosis on chronic inflammation? | [
"c19"
] | [
1
] |
19_3 | How do short-chain fatty acids contribute to immune regulation? | [
"c19"
] | [
1
] |
19_4 | What is the link between gut bacterial diversity and immune homeostasis? | [
"c19"
] | [
1
] |
19_5 | How does a lack of microbial diversity affect the human immune system? | [
"c19"
] | [
1
] |
20_1 | How is artificial intelligence being integrated into diagnostic radiology practices? | [
"c30"
] | [
1
] |
20_2 | Do deep learning algorithms replace radiologists or augment their diagnostic capabilities? | [
"c30"
] | [
1
] |
20_3 | What are the benefits of using AI tools to handle diagnostic backlogs in healthcare? | [
"c30"
] | [
1
] |
20_4 | How does AI technology help radiologists detect subtle irregularities in medical images? | [
"c30"
] | [
1
] |
20_5 | Can AI act as a second opinion in medical imaging diagnostics? | [
"c30"
] | [
1
] |
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