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Hemifacial spasm is a disorder of the seventh cranial nerve, and is characterized by irregular, involuntary and recurrent tonic and clonic contractions of the ipsilateral facial expression muscles . Each spontaneous motor paroxysm starts with eye twitching and progresses to involve the other muscles innervated by the f...
Varicella zoster virus (vzv) is a neurotropic dna alpha herpesvirus that infects more than 95% of the world population . Usually, varicella results from primary infection . The virus then becomes latent in ganglion neurons along the entire neuroaxis, and after reactivation, vzv moves transaxonally to the skin resulting...
This group of children has been identified as a highly vulnerable group that needs special attention and care . It has been reported that the number of street children range from 10 million to 100 million; the majority of them are living in major urban areas in developing countries.1 in amman, jordan, it is estimated t...
Sepsis is the systemic inflammatory response to infection and represents a major cause of morbidity and mortality in patients admitted to intensive care units (icus). However, despite decades of research, the pathophysiology of sepsis remains incompletely understood . A critical limitation of tissue oxygen delivery due...
An efficient photocatalyst minimizes recombination of photoexcited electron hole pairs and maximizes electron and hole transfer to the adsorbate upon consecutive surface reactions . In general, the photocatalytic activity of a given particle system depends on multiple factors . For a reliable photoactivity assessment, ...
The repercussions and clinical impact of this minimally invasive technological advance have been broadly highlighted in the international scientific literature and more recently expanded to pulmonology and thoracic oncology . Endobronchial ultrasound (known as ebus) has faced greater technical bottlenecks, related to t...
Prostate cancer is one of the most common cancers diagnosed in men in the united states: there were 238 590 new cases and 29 720 deaths recorded in 2013 . Prostate specific antigen (psa) is currently used as a diagnostic biomarker of prostate cancer . Psa is an androgen - regulated serine protease and a member of the t...
The national diabetes epidemic continues to expand, with about 1.6 million new cases each year and an overall prevalence of 23.6 million people . Additional 57 million american adults are at high risk for type 2 diabetes mellitus (t2 dm). The annual diagnosed diabetes incidence is projected to almost double from 8 case...
Recombinant human tgf-2 was obtained from r&d systems (minneapolis, mn, usa). (st . Louis, mo, usa) and calbiochem - emd millipore (temecula, ca, usa), respectively . As to primary antibodies, fascin was from millipore (temecula, ca, usa), e - cadherin from bd transduction laboratories (lexington, ky, usa), active -cat...
Direct coronary stent implantation is an elegant technique for coronary artery revascularization.1 however, calcified coronary lesions, often seen in older patients suffering from diabetes mellitus, renal failure and hypertension, are challenging to deal with, as they require optimal lesion preparation prior stenting f...
The emergency care system in denmark has been reorganized during recent years, and a danish quality database on emergency care has been established to assess, monitor, and improve quality . The danish quality database for prehospital emergency medical services (qems) is one of the three national sub - databases . The a...
Recent advances in array - based and sequence - based instrumentation have opened up new ways to monitor the inner molecular world of the cells and tissues that might be relevant to human diseases . Yet it is far from evident how these large datasets should be analyzed and how they can be integrated with other sources ...
The efficiency and function of the left ventricle (lv) as a pump are represented as systole and diastole . The systolic function is energy dependent; the diastolic function is an important part of cardiac output (as preload) and also includes active processes such as the suction effect, which is also energy dependent a...
The results of imaging studies are negatively affected by patients movements; hence, patient s cooperation is required during imaging . Children s movements and lack of cooperation are common indications for pediatric procedural sedation during imaging studies such as computed tomography (ct) scans (1). Different rates...
The common occurrence of these tumors is prevalent among males in their second or third decades of life with site predilection toward trunk and extremities, especially in the forearm . However, the incidence of al is extremely rare in the intraoral region, with only 21 reported cases in english literature . A 90-year -...
Attention deficit hyperactivity disorder (adhd) is a behaviorally defined disorder characterized by a persistent pattern of inattention and/or hyperactivity impulsivity that is more frequent and severe than typically observed in individuals at a comparable level of development (american psychiatric association, 2013). ...
Gingival recession is defined as the partial denudation of the root surface due to the apical migration of the gingival margin . Etiological factors include trauma from tooth brushing, malposition of teeth, ectopic insertion of frenum, and muscle attachments . The major therapeutic goals in mucogingival surgery are a c...
Nowadays a highlighted issue for an increasing number of consumers is the problem of meat tenderness, as the result of its physicochemical and biochemical mechanisms acting mainly on myofibrillar structures postmortem . Because calpastatin inhibits both calpain1 and calpain2, it remains unclear whether one or both calp...
Acupuncture is a promising treatment approach in patients with low back pain (clbp) with nearly the same or even better results compared to conventional therapy . Since in fact various acupuncture strategies are used in clinical practice, research in order to define the best acupuncture technique is of clinical interes...
The practice of psychiatry and the shift to noninstitutional care of severe psychiatric disorders are the result of antipsychotic medications, beginning with chlorpromazine in the early 1950s . Approximately 10 other drugs, known as first - generation or typical antipsychotics, followed over the subsequent 30 years . T...
Experimental approaches such as x - ray and electron crystallography and microscopy have traditionally excelled at determining the structure of single folded proteins and large protein complexes . However, intrinsically disordered proteins (idps) are not amenable to these static structural determination methods . Idps ...
The protocol has been approved by the institutional review board at the national institute of cholera and enteric disease . Briefly, fecal specimens were collected systematically from patients entering the hospital from november 2007 through february 2010 . Of note, the previous study analyzed data through october 2009...
Many neuroscientists have been calling for a system for the mouse brain where digital atlases serve as the framework used to traverse the brain and information linked to it (baldock et al ., 2003; bjaalie, 2002; boline et al ., 2007; mackenzie - graham et al ., 2003; martone et al ., 2004; toga, 2002). In contrast to d...
Oral angiokeratomas are most commonly found as a component of the generalized systemic disorder in fabry's disease or fucosidosis, where multiple angiokeratomas can be found on the skin and the oral mucosa . We report a rare case of a patient with multiple oral and scrotal angiokeratomas in the absence of a systemic di...
There are approximately 287,000 preventable maternal deaths annually, of which 99% occur in developing countries . As a sentinel event, maternal death is also a prime indicator in evaluating the quality of a nation's health care delivery systems [2, 3]. Mothers are pivotal to the social, economic, and cultural developm...
Patients show increasing declines in cognition, and behavioral symptoms occur in all stages of ad . While all ad patients can present with depression, agitation, and aggressive behaviors, behavioral difficulties are most pronounced in the advanced stages of the disease.13 rivastigmine, inhibiting both acetylcholinester...
Low aqueous solubility of drug has always presented major obstacle towards the development of drug delivery systems which often compromises patient compliance . Oral route is thought to be common and easy for drug administration . On oral administration of drug in its dosage form, it is expected to dissolve and release...
Health - care associated infections (hcais) are one among the major health related hazards and account for a major global disease burden . They pose a health threat toward patients and health care workers . These have a global impact and pose a disease burden to millions of people worldwide . These promote resistance t...
Resistance to fluoroquinolones (flq) and second - line injectable drugs (slid) is becoming more common, especially in eastern european countries, posing a serious threat to effective tuberculosis (tb) infection control . According to the most recent world health organization (who) report, extensively drug - resistant t...
Psoas abscess is characterized by infrequent incidence, insidious onset, and nonspecific clinical features, which can lead to misinterpretation and delayed diagnosis; thus, it is difficult to clinically diagnose psoas abscess1,5). Here, we present a rare case of tuberculous spondylitis and a large abscess in the left p...
Internet user population world - wide has doubled from 1.15 billion to 2.27 billion and has grown from 418 million to 1 billion in the last 5 years in asia . Rapid expansion and proliferation of the internet has provided better opportunities for communication, information and social interaction . However, the excessive...
Randomized controlled trials are primarily designed and conducted to meet the needs of regulatory bodies, so as to provide evidence on the efficacy and the safety of new drugs or other health care interventions . However, these studies are generally insufficient by themselves to meet the evidentiary needs of many healt...
Amyotrophic lateral sclerosis (als) is a progressive and fatal neurodegenerative disease characterized by the loss of lower and upper motor neurons, leading to muscle atrophy, paralysis, and death . Sleep disorders in patients with als are well - documented, and sleep - related complaints, such as insomnia, disturbed s...
Subdural spinal hematoma is an extremely rare complication of spinal and epidural anesthesia and may lead to cauda equina syndrome, bowel bladder dysfunction or even complete permanent paraplegia . A 60-year - old female patient was diagnosed to have osteoarthritis of right knee joint and was advised knee arthroplasty ...
Hypophosphatasia is a rare enzymopathy that normally presents within the first few years of life and often has profound effects upon the periodontium . It is characterized by low or zero levels of serum and tissue non - specific alkaline phosphatase, which is necessary for normal bone mineralization . It is a heritable...
Chagas disease (or american trypanosomiasis) was recognized by world health organization as one of thirteen neglected tropical diseases in the world . It was estimated that over 10 million people are infected, and latin america was considered the area of the highest prevalence . This parasitic disease is caused by tryp...
The prevalence and the severity of posture and gait disorders increase with ageing (salthouse and somberg 1982; maki et al 1994; mourey et al 1998; rankin et al 2000). Indeed, balance controlis a complex sensori - motor function which requires the integration of vestibular, visual, and somesthetic information into the ...
Conjunctival tick attachment is a rare occurrence, with only 7 cases reported in the literature . The tick species ixodes holocyclus is found in australia and belongs to the family of hard ticks, ixodidae, which are a group of blood - sucking acarine ectoparasites [1, 2]. It is also known as the paralysis tick because ...
Twenty - three patients were administered a high - dose and low - dose atd mixture (100 vs. 25 g amino acids) in a double - blind randomized crossover design with two sessions, separated by at least 4 days (booij et al . The 100 g and 25 g atd mixtures have previously been shown to lower plasma trp levels by approximat...
Metal - ceramic restorations have been successfully applied in restorative dentistry due to high fracture strength . However, achieving a natural translucency is more difficult with metal - ceramic restorations than all - ceramic restorations because metal substructures prevent light transmission in metal - ceramic res...
However, it has not been reported with fluoroscopically - guided endovascular procedures.the rapidly proliferating keratinocytes in the hair matrix are most sensitive to radiation . The insult damages the keratinocytes, which results in thin, weakened hair shaft that is susceptible to trauma.complete hair re - growth o...
Hemicrania continua (hc) is an uncommon primary headache disorder characterized by a continuous, mild to moderate intensity, unilateral headache [14]. Most patients will experience superimposed exacerbations of more severe pain, often associated with ipsilateral autonomic symptoms . Headache for greater than 3 months f...
The study population consisted of 85 caucasian, northern spanish girls representing a continuum of female subjects with hyperinsulinemic androgen excess that commences in prepuberty in those girls with a combined history of lbw and precocious pubarche, is followed by a preclinical phase starting around menarche of bioc...
The centers for disease control and prevention report that autism spectrum disorder (asd) now affects 1 in 88 children in the usa and 1 in 47 in utah . Asd is 5 times more likely in boys with 1 in 54 boys identified nationally . More children will be diagnosed with asd this year than with aids, diabetes, and cancer com...
The optimal time of catheter removal following radical prostatectomy (rp) is not defined . From a patient's perspective, early removal of the urinary catheter is desirable due to catheter - related discomfort, penile pain, bladder irritation / spasm, pericatheter urine leaks, etc ., however, the surgeon's concerns with...
Successful laparoscopic treatment has been described previously in only a few cases . Rarely the diagnosis is suspected preoperatively when using only ultrasound . Other diagnostic tests like magnetic resonance cholangiopancreatography (mrcp), endoscopic retrograde cholangiopancreatography (ercp) and intraoperative cho...
Phantom limb pain (plp) is classified as a kind of neuropathic pain that is induced after nerve injury . It is an after effect of amputation occurring in up to 50 - 85% of the patients,[13] and often leads to significant impairment in occupational and social functioning . Daily pain is reported by 48% of patients with ...
Isolated double - orifice mitral valve (domv) is an extremely rare congenital anomaly whose exact incidence has not been conclusively determined . Interestingly, this cardiac abnormality rarely presents as an isolated finding, preferentially associated with valvular regurgitation rather than stenosis . The etiology of ...
The largest mercury processing in the western hemisphere was in huancavelica in the peruvian andes, now a town of 30,000 people situated at 3676 m altitude . The extensive mercury deposits have been mined since pre - hispanic times, they are just above the present town at ~4000 m. although the mine closed 30 years ago,...
In the present issue of critical care, linder and colleagues present a new study in which they assess the clinical importance of serial measurements of heparin - binding protein (hbp) plasma levels in critically ill septic and nonseptic patients . They found that hbp plasma levels are significantly higher in patients w...
The information gathered during pre - marketing drug development is inevitably incomplete with regard to possible adverse reactions . This is mainly due to: animal testing is insufficient to predict human safety;patients enrolled in clinical trials are selected and limited in number;the conditions of use are different ...
Periapical pathoses of pulpal origin develop in response to microbial irritants in the root canal systems . Bacterial cell wall components react with monocytes, macrophages, other cells of the immune system, as well as with fibroblasts, leading to the production of proinflammatory cytokines, such as il-1, il-1, tnf-, i...
The traditional management of gallstone pancreatitis (gp) has been to perform cholecystectomy during the same hospital admission after resolution . However, when gp develops in the immediate postoperative period from a major colorectal operation, cholecystectomy may be fraught with difficulty due to the inflammatory re...
High - grade gliomas, who grade iii or iv [1, 2], are the most common primary brain tumors in adults [1, 3]. Who grade iv tumors are almost exclusively (8090%) glioblastoma multiforme (gbm), which are the most common high - grade glioma (4045%) [1, 3], the most common form of brain tumor overall (1215%) [1, 3], and the...
Adrenal myelolipoma is a tumor - like lesion composed of variable amounts of mature adipose tissue and bone marrow elements . In spite of wbc and rbc precursors such as megakaryocytes giercke in 1905 first described and 24 years later, oberling coined the term myelolipoma. Only two cases under the age of 16 are reporte...
Nutcracker syndrome is generally referred to as the compression of the left renal vein between the superior mesenteric artery and aorta (1). This compression leads to lrv hypertension and results in direct communication of the renal vein with the calyceal cavity and the varicosities of the collateral pathway of the lrv...
Since the international subarachnoid trial, coil embolization of aneurysms is now accepted as a primary optional treatment19). However, endovascular treatment (evt) of middle cerebral artery (mca) aneurysms has been less often applied in many institutions because of the feasibility of surgical clipping afforded by the ...
Co2mnsi samples were prepared and investigated completely in situ in an ultrahigh vacuum cluster consisting of sputtering chambers, an molecular beam epitaxy (mbe) chamber, and a srups chamber equipped with a he gas discharge lamp (h=21.2 ev) and a hemispherical energy analyzer with multi - channel spin filter27 (energ...
Mucocutaneous lymph node syndrome, which had been affecting infants and young children in japan . Diagnosis requires fever and 4 out of 5 principal clinical features (conjunctivitis; erythematous lips, oral cavity; palms and soles; polymorphous exanthema of the body trunk; swelling of the cervical lymph nodes) or if fe...
Expression of genes is regulated at many different levels, transcription of dna being one of the most critical stages . Specific configurations of transcription factors (tfs) that interact with gene promoter regions are recruited to activate or modulate the production of a given transcript . Many of these tfs possess t...
It is well known that job stress is responsible for poor work performance, high absenteeism, less work productivity, and several diseases.15 recently, results from thirteen independent cohort studies in europe indicated that job strain is responsible for coronary heart disease, as are lifestyle and orthodox risk factor...
Detection of beta globin gene lesions in thalassemic patients and carriers is based on screening for the mutations most often found in the relevant ethnic group . But in circumstances in which an unknown mutation is encountered, another difficulty arises when at - risk couples present at a late stage of pregnancy with ...
Tendinopathy is an overuse tendon injury that occurs in loaded tendons and results in pain and functional impairment, a major problem in sports and occupational medicine . Characteristic changes in tendon structure include loss of type i collagen, increase in proteoglycan content, and neovascularization . This has been...
Livestock animals are subjected to a huge sort of stress factors, such as environmental conditions, animal management or diets that may disrupt the intestinal ecosystem and increase the risk of pathogenic infections . In the swine industry, transition from the liquid to a solid diet during weaning and post - weaning ar...
Transposable elements (tes) dispersed in the mammalian genome are on the rise, as completion of the whole human genome sequence . Contrary to our expectations, tes, thought to be junk dna, were estimated to account for approximately 45% of the human genome (international human genome sequencing consortium, 2001). Tes c...
Sarcomas are a group of very uncommon malignant tumors that compromise 1% of all adult malignancies.1 approximately 11,590 new diagnoses and 3,560 deaths from soft tissue sarcomas (sts) and bone sarcomas occur annually in the united states.1 isolated pulmonary metastases from sts occur in 20 - 50% of these patients, an...
Obsessive compulsive disorder (ocd) is a common psychiatric disorder (2% - 3% of the general population) which is diagnosed easily most of the time by the psychiatrist or even the physician . It is sometimes very difficult to properly diagnose a person for ocd based only on an interview . The presentation of ocd may be...
The new drg - based prospective payment system (pps) for medicare is a revolutionary concept in health care finance . It introduces a new approach to reimbursement, which is based upon a defined clinical product . In contrast, under retrospective cost - based reimbursement, each component of the process of care (each v...
Obstructive sleep apnea (osa) is a highly prevalent and underdiagnosed disease.1 a recent large clinical trial established osa as a novel risk factor for sudden cardiac death (scd).2 after 20 years of followup, the busselton health study cohort showed that moderate to severe sleep apnea was independently associated wit...
Parkinson's disease (pd) is a debilitating neurologic disorder characterized clinically by bradykinesia, resting tremor, rigidity, and postural instability with a therapeutic response to levodopa . Pathophysiologically, pd is characterized by the loss of dopamine neurons in the substantia nigra (sn) pars compacta and b...
We did a single - center retrospective analysis of seven patients with pelvic abscess treated by eus transrectal drainage between january 2010 and august 2014 . There were four men and three women, with a median age of 50 years (range 22 - 68). A concomitant intravenous antibiotic treatment was always administered be f...
The reovirus 2 protein catalyzes mrna capping, that is, addition of a guanosine to the 5' end of each transcript in a 5'-to-5' orientation, as well as transfer of a methyl group from s - adenosyl - l - methionine (adomet) to the n7 atom of the added guanosyl moiety and subsequently to the ribose 2'-o atom of the first ...
Helicobacter pylori is the most common chronic bacterial infection in humans, affecting 50% of the world population . Chronic colonization increases the risk of duodenal ulcer and gastric cancer, including adenocarcinoma and mucosa associated lymphoid tissue (malt) lymphoma . The relative risk of gastric carcinoma in i...
Chronic sialadenitis is one of the major disorders that can cause salivary hypofunction and correct diagnosis and management is essential for its recovery . The classification of this pathological condition has changed in the past decade and nowadays was revised and modified, for new diagnostic (high - resolution ultra...
Diabetes mellitus (dm) is one of the most common chronic metabolic diseases, which is on the rise globally.123) the dm prevalence for all age groups worldwide was estimated to be 2.8% in 2000 and projected to be 4.4% by 2030 . During this period, the total number of people with dm is expected to rise from 171 million t...
Core autism symptoms such as social communication deficits have proven difficult to change through social skills training (rao et al . 2008). Although several large - scale interventions for young children with autism such as pivotal response treatment meet american psychological association criteria for probable effic...
It is characterized by neuropsychiatric manifestations . In minimal hepatic encephalopathy (mhe), patients have alterations in sleep pattern, and there is difficulty in performing even day - to - day routine activities like driving a vehicle, doing simple calculations, and so forth [13]. Initially there is a mild impai...
Pseudocholinesterase (pche) is an enzyme with a complex molecular structure.1 it is synthesized in the liver and immediately released into the plasma.2 the plasma half - life has been estimated to be approximately 12 days.3 deficiency or reduced activity of this enzyme results in significant prolongation of mivacurium-...
Six and 18monthold male c57 and mdx mice were euthanized, and the tibialis anterior (ta) muscle and the diaphragms were dissected . They were either flash frozen in liquid nitrogen for biochemical analysis or embedded in oct and frozen in melting isopentane for histological evaluation . Portions of ta and diaphragm wer...
With the aging of the population worldwide, dementia is a real public health priority . In 2000, the estimated number of dementia cases was 25.5 million people, representing 0.4% of the worldwide population . Nearly two thirds of all people with dementia lived in low- and middle - income countries . The other most impo...
See detailed information on materials, virus construction, quantitative pcr, and adipocyte area measurement in the supplementary methods . Adipoq mice were created as previously described (5) on the 129/svev genetic background and had been back - crossed to c57bl/6 for five generations . The experiments using mouse mod...
The national library of medicine's (nlm) medline / pubmed biomedical literature database () is rapidly expanding and as of the 2006 edition, the baseline database contains more than 15 million citations . A number of papers have introduced tools to perform searches more advanced than those available with the current en...
Lymphangioma circumscriptum (lc) or microcystic lymphatic malformation is a hamartomatous malformation of the lymphatic channels of the skin . Treatment of lc is difficult because of the persistent nature of the disease due to deeper subcutaneous cisternal connections . We report here a case of lc treated effectively w...
A patient was immediately referred to our department after epidural endoscopy with severe bilateral visual impairment and underwent complete ophthalmologic examination . A 45-year old man suffered from low back pain unresponsive to pharmacologic treatment, radiating to the left hip and left lower extremity, due to a ba...
The human genome is laden with repetitive sequences in the form of transposable elements (tes) and tandem repeats, which comprise 45% and 3% of the human genome, respectively . Using new methods capable of annotating repetitive sequences that have substantially diverged from known te sequences, recent analyses indicate...
One important and interesting problem in genome research is the prediction of transcription factor binding sites (tfbss). Binding of transcription factors to their dna binding sites in the regulatory region of a gene is a prerequisite for its activation or repression . The combinatorial presence of tfbss controls gene ...
Spinal epidural hemangiomas have been reported in the literature, but most of them were cavernous type hemangiomas that enable a preoperative differential diagnosis with relative ease . The limited number of spinal epidural hemangiomas and few radiological findings make an exact diagnosis difficult prior to surgery . A...
Numerous investigators have reported improved function, reduced pain, and high rates of implant survivorship at up to 20 years followup [4, 29]. However, concerns about limitations in implant longevity related to the osteolysis associated with metal - on - polyethylene (m - pe) bearing surface wear have led to innovati...
Out of the 10,807 patients enrolled for the original survey, access survival data were available for 7058 (65%) patients . These patients resided in portugal, the united kingdom, ireland, italy, turkey, romania, slovenia, poland, and spain . The mean age was 63.515.0 years, 38.5% were female, 27.1% were diabetic, 90.6%...
The developing vertebrate heart tube contains an outer layer of myocardium and an inner layer of endocardium separated by an extracellular matrix (ecm) referred to as the cardiac jelly . During heart valve formation, a subset of endocardial cells in the atrioventricular (av) canal (avc) region is specified to delaminat...
Schwannoma may arise from any peripheral nerve and is often found in the chest wall and posterior mediastinum . However, case reports of intrapulmonary schwannoma are extremely rare . A 38-year - old man was referred to our institution because of an abnormal shadow found incidentally on the chest x - ray . The plain ch...
A pulmonary nodule is defined as a spherical well - circumscribed radiographic opacity that is surrounded completely by aerated lung . Lesions that are larger than 3 cm are described as lung masses . As size has been shown to be important for classification of nodules (see below) the term micronodules is usually applie...
Stressful life experiences have the amazing ability to synchronize organism - wide physiological responses toward the common goal of surviving threat . In this way, the major stress - responsive systems are often regarded by evolutionary biologists as essential adaptive mechanisms that ultimately promote survival . How...
Hemorrhage from pelvic blood vessels after trauma or obstetric delivery are major health care problems . Trauma is a leading cause of death worldwide and a major cause of lost quality - adjusted life years (qalys). Treatment of pelvic trauma is difficult since hemorrhage can be massive and it is difficult to apply dire...
Cell culture performed as previously described . Briefly, k562 cells (atcc) were cultured in rpmi 1640 (gibco) media and supplemented with 10% fbs (hyclone), penicillin (10,000 i.u./ml), streptomycin (10,000 ug / ml), and l - glutamine (2 mm). Cells were grown in log phase during all biological assays by returning the ...
Clinical presentations vary from nonspecific systemic symptoms (e.g., fever, myalgia, palpitation, chest pain, dyspnea) to fulminant hemodynamic collapse and sudden death . Infections (viral, bacterial, fungal, protozoal, parasitic), toxins, immunological syndromes, and hypersensitivity can cause myocarditis . Among th...
Liver cancer is the second most common cause of cancer - related death worldwide, the fifth most common cancer among men and the ninth most common cancer among women.1 hepatocellular carcinoma (hcc) is responsible for ~90% of primary liver cancers.2 in the united states, hcc is the fastest rising cause of cancer - rela...
Conidiation in aspergillus involves many common developmental themes including spatial and temporal control of gene expression, specialized differentiation of cells, and intra and intercellular communications . Conidiation is regulated by an asexual developmental signaling pathway that directs expression control elemen...