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Blow - out fracture of the inferior orbital wall is defined as fracture of an outer wall that supports the lower part of an orbit by the impact of blunt trauma, producing increased internal pressure . The importance of the diagnosis to treatment of the blow - out fracture is rising because of industrialization, increas... |
Microbial ecologists have devoted considerable effort to understanding the nature of the viruses in seawater, because viruses have key roles in the evolution, ecology and mortality of marine plankton (rohwer and vega thurber, 2007; suttle, 2007). For at least the past two decades, researchers have assumed that the pool... |
The national health insurance system in taiwan is compulsory and covers all citizens except prisoners . The taiwan national health insurance research database (nhird) was released for research purposes by the national health research institute (19) and is one of the largest and most comprehensive databases in the world... |
Iran is located in western asia, with over 77 million inhabitants and also more than two - thirds of the population is under the age of 30 with one - quarter being 15 years of age or younger . Iran also exhibits one of the steepest urban growth rates in the world and approximately over 70 percent of iran's population l... |
A 2-year - old child was admitted to the department of pediatrics at the jawaharlal institute of postgraduate medical education and research (jipmer), puducherry, india, with a provisional diagnosis of cholera . Before the child received antimicrobial therapy, a fecal specimen meanwhile, a strain of v. cholerae o1 el t... |
Prostate cancer (pca) is the fastest growing cancer in korea . According to the statistical data of the national cancer information center, the incidence of pca, 8.5 per 100,000 population in 1999, the annual growth rate, 13.5%, is the fastest of all cancers in korea . Radical prostatectomy (rp) is the standard treatme... |
The -subdivision of proteobacteria includes gram - negative bacteria with diverse and contrasting lifestyles, ranging from free - living, symbiotic to pathogenic bacteria . Despite this apparent heterogeneity, -proteobacteria share some unexpected common features such as an asymmetric cell division followed by a differ... |
Solanaceae, the nightshade family, as a group represents the third most valuable crop family in the us, exceeded only by the grasses and legumes, and the most valuable family in terms of vegetable crops providing important dietary contributions to human health and nutrition . Tomato (solanum lycopersicum until recently... |
There is mounting evidence indicating that the static neck posture frequently assumed by computer workers using a computer is a risk factor for work - related neck and upper - limb disorders1, 2 . During computer work, use of the cervical erector spinae (ces) muscles is important for efficient muscle activation and sup... |
(2009) address the production of il-9 by helper t cells, a finding that is of interest because of recent studies that found tgf- could induce the differentiation of th9 cells with a unique pattern of cytokine expression and a transcription factor profile that could not be pigeonholed into the framework of the th1, th2,... |
Many us americans consume diets that are overly high in energy and in constituents associated with disease risk, particularly saturated fat (sfa), cholesterol and sodium and low in protective components such as fiber or -carotene . Poorly balanced diets contribute to overweight, cardiovascular disease, type 2 diabetes ... |
Methacrylate - based resin cements are popular for attaching indirect restoratives, appliances, and fiber posts to the prepared teeth due to their less technique sensitivity, good esthetics, high bond strength, and a potential for fluoride release.1 - 4 as luting agents for indirect restorations, resin cements are need... |
Obesity is an increasingly prevalent problem in the united states . Seventeen percent of children and 32% of adults in the us meet the clinical definition of obesity . In adult men and in adolescents of both sexes, these numbers have been climbing over the past 6 years, and in women the rate of obesity seems to be leve... |
Pyogenic liver abscess (pla) is a crucial clinical disease that can be fatal without prompt recognition and treatment . An increasing number of studies have demonstrated that pla in western and asian countries differs in many aspects, including demographic characteristics, etiological factors, and clinical manifestatio... |
Osteoarthritis (oa) of the knee is a common problem causing knee pain and physical disabilities in the elderly1 . The prevalence of knee oa is known to increase with age not only in japan but also in various countries, meaning it is an important social issue around the world2, 3 . Recently, research on osteoarthritis a... |
Species of microsporidia are obligate intracellular protozoans that have been recognized among broad spectrum of invertebrate and vertebrate hosts (1, 2). Almost 1200 species of microsporidia belong to more than 140 genera were described, so far (1, 3, 4). Since the first human microsporidiosis was identified in 1959, ... |
Globally, solid waste management is one of the greatest environmental health challenges and continues to overwhelm local authorities and national governments as urban populations continue to rise and consumption patterns change [13]. Cities generate about 1.3 billion tonnes of solid waste per year, a volume expected to... |
Slow waves and sleep spindles are the essential elements in the definition of sleep stages . They recently received additional attention because of their hypothesized involvement in processes related to neuronal plasticity, learning, and memory [24]. Furthermore, slow oscillations (<1 hz) are considered as a central fe... |
Despite the declining incidence of gastric cancer in western countries, gastric cancer is the most frequently diagnosed cancer worldwide, and is one of the main causes of cancer deaths . In patients with advanced gastric cancer with distant metastasis or recurrence, systemic chemotherapy has been recommended as standar... |
Fabry disease (fd) is a rare x - linked disorder resulting from a deficient activity of the lysosomal enzyme -glycosidase a (-gal a) that leads to progressive accumulation of glycosphingolipids in several tissues and organs . In the classical form of the disease, renal involvement commonly ensues in the second to third... |
Embryonic pancreata were harvested from time - mated cd1 strain mouse intercrosses of ngn3 females and males and stored individually in rnalater (ambion) at 4c until genotyping by pcr (30 cycles; ngn3 forward, 5-cctcttctggctttcactac-3 and reverse, 5-ggagcgagagtttgatgtgg-3; neomycin forward, 5-gtcttgtcgatcaggatgatctc-3 ... |
Cow s milk allergy is the most common food allergy in children . Symptoms usually involve the skin and the gastrointestinal and respiratory tracts . Gastrointestinal tract manifestations of cow s milk allergy are nonspecific, and are the only type that can be diagnosed in all age groups . Here, we report a rare case of... |
Unsaturated amine borane complexes have been known for many years to be isolable molecules that easily survive exposure to the air at room temperature. (1) this stability can be attributed to the strength of the bond between nitrogen and boron in the lewis acidlewis base complex and is consistent with prior reports tha... |
Boletus griseipurpureus (boletaceae) is a wild edible ectomycorrhizal mushroom, rich in protein and low in fat (1). An analysis of the internal transcribed spacer (its) region for b. griseipurpureus from the south of thailand revealed a monophylogenetic clade (1). However, only its sequences cannot indicate the differe... |
Implantable cardioverter defibrillator (icd) implantation is performed at many centers in korea,1)2) however, icd lead extraction has not yet been reported . We report our experience of icd lead extraction using locking stylet and polypropylene dilator sheath in a patient with recurrent inappropriate shocks due to lead... |
Project budburst (budburst.org) is a citizen - science program in which ordinary people including kids ten years old and up observe and upload information about bloom times and other life stages of plants (called phenophases) to a national database online . This site has been actively storing phenological information s... |
A broad and heterogeneous group of syndromes may result from this process, since any type, size, and location of blood vessel may be involved . Vasculitis and its consequences may be the primary or sole manifestation of a disease; alternatively, vasculitis may be a secondary component of another primary disease like in... |
Nebivolol is a third - generation 1 - selectiveblocker that is indicated for the treatment of hypertension and heart failure . It has vasodilatory properties mediated by direct stimulation of the endothelial nitric oxide synthase (enos). Nebivolol is a racemic mixture of two enantiomers in a 1:1 ratio, namely a d - and... |
Clinically, calcineurin inhibitors (e.g., cyclosporine a, csa) have been used to reduce proteinuria in focal segmental glomerulosclerosis (fsgs), minimal change disease (mcd), and other proteinuric kidney diseases . T - cell dysfunction is associated with some forms of proteinuria, including a subset of mcd in children... |
Histopathology of type 1 lepra reaction shows edema within granuloma separating inflammatory cells with density of lymphocytes in the dermis . To distinguish between upgrading and downgrading reaction histopathologicaly, serial examination of biopsies histopathology of skin lesions of type 2 lepra reaction (erythema no... |
In addition to the progresses made in the areas of surgical techniques and surgical tools, efforts are being made to take surgical measures for the patient in such a manner so that they are economical and with less side effects and least hospitalization period in addition to maximum benefits for the patient regarding t... |
The patient is a 58 years old iraqi male that referred to our center three months after an unsuccessful operation for removing a subhepatic mass, probably adrenal mass . He experienced general weakness, fatigue, and weight loss in the last several months . A scar of previous surgery in the right subcostal area (subcost... |
Avian influenza is a highly contagious viral disease of major concern to both the poultry industry and human health; the currently ongoing outbreaks of h5n1 since 1997 have been unprecedented with over 500 million birds destroyed and over 303 humans dead . This development has ignited a global fear of imminent influenz... |
Invasive cervical cancer (icc) is the leading cause of cancer - related deaths among women in developing countries . It is the second most common cancer among women worldwide with an estimate of over 500,000 new cases and about 275,000 deaths in 2008 . About 86% of these cases occur in developing countries representing... |
There currently is considerable interest in developing therapeutic strategies to enhance plasticity of the adult central nervous system (cns). Physical exercise, diet, and various forms of environmental / cognitive enrichment have all been proposed to facilitate plasticity [14]. For example, the maturation and strength... |
Glycogen storage diseases (gsd) are a group of disorders caused by alteration of the enzymes involved in glycogen metabolism, producing an accumulation of glycogen in several tissues . The most frequent type of glycogen storage disease is gsd ix, which incidence is 1:100,000 births and is responsible for 25% of all gsd... |
Thus, vision loss is a major medical, economic, safety, and social issue affecting millions of persons worldwide . Neurodegenerative diseases of the retina involve progressive and irreversible loss of retinal neurons, their connections and supporting glia, thereby leading to impaired visual function . Major neurodegene... |
Panthothenate kinase - associated neurodegeneration (pkan), formerly termed as hallervorden - spatz disease is a rare chromosomal disorder first described by hallervorden and spatz in 1922 . The characteristic features in patients with pkan include dystonia, muscle spasm, cognitive dysfunction, and seizure disorder . T... |
A 42-year - old female patient was admitted to the department of dentomaxillofacial radiology, faculty of dentistry, ankara university with a complaint of bleeding on the gums . The patient's medical history included having undergone treatment for pernicious anemia and a gastric ulcer two years earlier . On intraoral e... |
Patients with collagen vascular disease (cvd) such as rheumatoid arthritis, systemic lupus erythematosus, scleroderma, polymyositis, and dermatomyositis, are known to be sensitive to ionizing radiation 19 . Irradiation to the lung in patients with interstitial pneumonia (ip) is also considered a relative contraindicati... |
Infection with the hepatitis b and c viruses (hbv and hcv) causes significant morbidity and mortality . Even though hbv infection can be prevented through vaccination, the world health organization (who) has estimated that globally around 240 million people are chronically infected [1, 2] with between 500 000 and 700 0... |
In february 1997, rotavirus infection was diagnosed (by page analysis) in a 2-year - old child hospitalized with severe acute diarrhea at the g. di cristina the virus, pa260/97, exhibited a long e - type and was recognized by an sg - specific monoclonal antibody (mab) and by a vp7-specific mab as sgi and g3 (6). Accord... |
Human sparganosis is a zoonosis caused by plerocercoid larvae (= spargana) of pseudophyllidean (now classified as diphyllobothriidean) tapeworms . In asia, s. erinaceieuropaei is responsible for this disease, whereas spirometra mansonoides is important in the americas . This parasite can be found anywhere in the body i... |
Megalocornea is a nonprogressive bilateral congenital enlargement of the anterior segment in the absence of raised intraocular pressure.1 it can occur in three forms simple megalocornea unassociated with other ocular abnormalities; anterior megalophthalmos with megalocornea; and iris and angle abnormalities as well as ... |
This is an investigator - initiated phase iii double - blind, randomized, placebo - controlled, two - arm crossover clinical study . The study adhered to the guidelines of the declaration of helsinki, and the protocol and consent form were approved by the local investigational review board, the national ethics committe... |
Trimethyltin (tmt), a short - chain trialkyltin, is used as a stabilizing agent for certain plastics and is a neurotoxin that induces neuronal damage in both humans and experimental animals [1 - 3]. Tmt causes a selective degeneration of pyramidal neurons in the hippocampus and the cortical areas connected to the hippo... |
1a). Four trials used tid dosing, three used bid dosing, and all but one trial (pregabalin 300 mg / day vs. placebo) used escalation to assigned fixed dosing over a period of 1 to 2 weeks . Patients were randomized to placebo or fixed - dosage pregabalin at 150, 300, or 600 mg / day . One trial included a 75-mg / day d... |
Focal segmental glomerulosclerosis (fsgs) causes scarring or sclerosis of glomeruli that act as tiny filters in the kidneys, damage to which results in diminished ability to properly filter blood, resulting in the urinary loss of plasma proteins and subsequent proteinuria . A 60-year - old, white female with a history ... |
Materials from renewable resources have the potential to be more environmentally friendly than polymer materials of petrochemical origin.1 the annual production of chitin in nature is estimated to be in the range of 10100 trillion tones, and the seafood industry generates large amount of chitin waste.2 the disposal of ... |
Nine patients with type 2 diabetes and eight healthy control subjects gave informed consent to the approved protocol . Patients with poor metabolic control were intentionally chosen . Lipid profile and inflammatory proteins (fibrinogen, von clauss method; haptoglobin and immunoglobin g, immunonephelometric method; and ... |
Neuromyelitis optica (nmo) has been traditionally considered a predominantly opticospinal disorder, but recent studies have shown that clinical spectrum of nmo includes cerebral and brainstem syndromes as well [13]. Brain lesions on magnetic resonance imaging (mri) are found in the majority of nmo patients with long - ... |
Nanoparticles are a special group of materials with unique features and extensive applications in diverse fields.1 metal nanoparticles, such as those containing gold and silver have recognized importance in chemistry, physics, and biology because of their unique optical, electrical, and photothermal properties.2 the ea... |
Each year, more than forty million abortions are occurred whole of the world (1). Most of the inducible abortions are performed by surgical methods as the gold choice procedure however may lead patients dissatisfaction and postoperative serious complications (2). By advancing medical services as alternative methods for... |
New psychoactive substances (npss) are continuously emerging on the recreational and illicit drug market . They are often referred to as legal highs, designer drugs, or they are mainly synthetic derivatives and analogues of existing controlled drugs, analogues of pharmaceutical products, herbs, fungi, and their extract... |
The university medical center groningen is a tertiary referral center in the northern part of the netherlands . We perform routine diagnostic real - time pcr for all patients evaluated for respiratory disease by laboratory developed tests for 17 targets, including adenovirus, bocavirus, coronavirus, enterovirus, metapn... |
The fundamental manifestation of the aging process is a progressive decline in the functional maintenance of tissue homeostasis and an increasing propensity to degenerative diseases and death . It has attracted significant interest to study the underlying mechanisms of aging, and many theories have been put forward to ... |
Staphylococcus aureus is an important bacterial pathogen that may cause a variety of diseases, ranging from common skin and soft tissue infections to very serious and lethal diseases such as septic shock, toxic shock syndrome or pneumonia (1, 2). Although antibiotic therapy is currently used to treat s. aureus infectio... |
Publication ethics is a multidimensional concern that affects numerous groups such as authors, editors, reviewers, researchers, scholars, learned societies and organizations, policy makers, practitioners, clinicians, funders, and many other stakeholders . What is generally expected of scholarly publications is, first a... |
We conducted a single - center, open - label, randomized clinical trial to evaluate the progression of -cell dysfunction over 3.5 years in patients with treatment - nave newly diagnosed type 2 diabetes . All patients were treated for 3 months with insulin and metformin and then randomly assigned to treatment with eithe... |
Fusion and gemination are the terms used to describe joint and double formation of teeth . Fusion is generally regarded as a union of two or more hard tissues of two or more teeth, and the number of teeth in the affected arch is usually less than one . However, definitive diagnosis is difficult, because a normal tooth ... |
Hemorrhage and perforation are the most common complications after colonoscopy occurring in less than 1% of patients and often associated with biopsy or polypectomy . Splenic injury or rupture is also an infrequent complication that is often forgotten and may require urgent surgical intervention . The first case of spl... |
Medical devices, which have a physical mode of action, are widely employed to control head louse infestation in europe and, more recently, in australia . However, in most countries, competent authorities and national prescribing schemes still generally favor insecticide - based medicinal products over medical devices f... |
Pleural mesothelioma is a rare condition associated with exposure to asbestos in around 70% of the cases . Other risk factors include sv40 virus, genetic alterations, and exposure to radiotherapy generally for cancer treatment . The relationship between exposure to radiotherapy and pleural mesothelioma has been documen... |
Dental caries is the most common chronic disease of childhood and significantly impacts children's well - being . Among us children aged from 2 to 5 years of age, more than 25% have caries, a prevalence which appears to be on the rise . Yet, young children, particularly those who are low - income, encounter substantial... |
We selected eight genes known to be involved in the ras pathway, namely cdk5, hras, mapk1, mapk3, map2k1, map2k2, ngfr and raf1 . Core genes due to their relevance in the ras pathway and their consequential importance in colorectal cancer . The knock - down experiments were performed on the eight core genes using short... |
Other concomitant symptoms should be considered for diagnostic approach in a child with pleuritic chest pain . In this report we discuss chest pain in a 6-year - old child with regard to other signs and symptoms . This six - year old boy was presented to the emergency department of children's medical center, tehran, wi... |
A 24 y / o single, educated, mother is hesitant to have her 12 mo daughter vaccinated for measles, mumps and rubella (mmr) due to concerns of her developing autism . Student objectives: to discuss the actual risks and benefits of the mmr vaccine and to debunk the link the between the mmr vaccine and autism by describin... |
(1) patients may report dysuria, intermittency, haematuria, frequency, hesitancy, nocturia or sudden termination of voiding . A 62 year old lady presented to the hospital with a swelling in her right thigh . She had a past history of myelomeningocele spina bifida which had been closed at birth . She suffered from urina... |
The plasma membrane serves as a highly dynamic platform for binding of peripheral membrane proteins and their complexes, a phenomenon that is involved in the regulation of a wide range of cellular and physiological processes, e.g., intercellular signaling, membrane trafficking, and coagulation . As the association of p... |
Inversion traction (it) is a form of spinal traction in which the body is maintained in an inverted position so that back problems can be prevented and cured1 . Specifically, it provides the spinal column with traction force using the body s weight . The force of the body s weight in the it position is usually calculat... |
Patients or individuals may not respond in similar ways when administered with the same drug in a standard dose . Both genetic and non - genetic factors including age, gender, nutrition, concomitant medications, organ function however, to a great extent the inter - individual variability in drug response is attributabl... |
A computed tomography (ct) incidentaloma is an incidentally detected and previously unsuspected finding or abnormality that is not related to the indication for obtaining the ct examination . Chest ct incidentalomas are pandemic in modern health care due to many factors, including the explosion in the use of chest ct s... |
Acrodermatitis enteropathica (ae) is an autosomal recessive condition resulting in severe zinc deficiency . The deficiency is caused by a defect of dietary zinc absorption in the duodenum and jejunum . Zinc is an essential co - enzyme in metal enzymes (like alkaline phosphatase); it is an important structural component... |
Diffusion tensor imaging (dti) is a noninvasive magnetic resonance imaging (mri)-based technique that is increasingly used to characterize microstructural brain changes in parkinson's disease (pd). Mean diffusivity (md) and fractional anisotropy (fa) are common dti measures extracted from the diffusion tensor which mea... |
Ins-1 cells (passage 545) were cultured in rpmi1640 medium (sigma) containing 11.1 mmol / l d - glucose supplemented with 10% heat - inactivated fbs, 10 mmol / l hepes, 100 units / ml penicillin, 100 mg / ml streptomycin, 1 mmol / l sodium pyruvate, and 50 mol / l -mercaptoethanol at 37c in a humidified incubator conta... |
Anxiety among patients is present in the operation theatre set up with a reported incidence of 60%80% . Lengthy surgical procedures, anaesthesia, unfamiliar surroundings and unexpected delays typically increase patient anxiety . Approximately, one - third of patients having surgery under regional anaesthesia are highly... |
Hypoxia is suggested to play an important role in the pathogenesis of endocrine and metabolic dysregulation in obesity and the metabolic syndrome . We could previously demonstrate, based on an experimental human in vivo design established in our group, that 30 minutes of oxygen desaturation to 75% are sufficient to ind... |
Lymph edema is the accumulation of a high - protein edema fluid in the interstitial tissue as a result of the functional overload of the lymphatic system in which lymph volume exceeds transport capabilities and the lymphatic system becomes overwhelmed, causing lymphatic insufficiency or failure1 . Secondary lymph edema... |
Due to the stringency of cellular quality control (qc), protein production and assembly are often inefficient in the cell . About 30% of newly synthesized proteins in mammalian cells are subject to rapid degradation by proteasomes . However, experimental efforts to rationalize the interplay between the physiochemical p... |
Tamoxifen is an effective treatment in reducing recurrence and mortality rates for estrogen receptor (er) positive breast cancer patients 1 . On the other hand, an undesirable side effect of increasing risk of endometrial cancer has been suspected for decades 2 - 6 . A number of case - control studies showed that the r... |
Metzincin matrix - metalloproteases (mmps) comprise a large family of endopeptidases of which today, 24 distinct genes have been identified in man (only 23 have been identified in mouse). The prefix metallo- refers to the reliance of these endopeptidases on zinc ions to perform hydrolysis of their respective protein su... |
Neuroimmune interactions are increasingly appreciated as both an important regulator of normal brain development and function and a potential contributor to the pathophysiology of a range of neuropsychiatric illnesses . In particular, there is accumulating evidence that immune dysregulation can contribute to obsessive ... |
Sarcoidosis is a very rare disease in korea with an incidence of 59 cases in 1998 (0.125 cases/100000 people)11). Hydrocephalus is a rare clinical feature with a prevalence of 6% among patients with neurosarcoidosis, as reported by a prospective study2). Secondary hydrocephalus following meningitis, ventriculitis, or h... |
La agudeza visual no corregida y corregida (udva, cdva) mejor considerablemente a los 9 meses de la intervencin, y continuaron mejorando significativamente hasta el ltimo seguimiento a los 5 aos de la misma . El tratamiento result seguro y efectivo, con mejora continua de la agudeza visual durante los 5 aos posteriores... |
There is a robust corpus of behavioral studies showing that, at a young age, infants discriminate phonetic contrasts from different languages of the world (e.g., [14]). The capacity of infants to acquire linguistic information from their native language is well established, but the mechanisms neural or other underlying... |
Fecal microbiota transplantation (fmt) has gained worldwide attention in recent years 1 . In 2013, it was recommended as the clinical choice in guidelines for treatment of recurrent clostridium difficile infection (cdi) 2 . In addition, clinical studies have shown that fmt has a therapeutic role in inflammatory bowel d... |
In 2010, about 8,900 ontario women were diagnosed with breast cancer while 2,100 died of the disease . Compared to women without a family history of breast cancer, women with an affected first - degree relative are about twice as likely to develop breast cancer, with risks increasing when any first - degree relatives a... |
Porcine circovirus (pcv) is a small nonenveloped virus that contains a single - stranded circular dna of about 1.76 kb . Pcv was originally isolated as a noncytopathic contaminant of the pk-15 cell line and was classified as a member of circoviridae family, genus circovirus, based on its morphological and genomic chara... |
Hydatidosis is a chronic infection of medical and veterinary importance caused by the larval stage of cosmopolitan parasitic platyhelminth echinococcus granulosus . This disease is considered as re - emerging zoonosis in several countries and endemic in algeria; it is considered as disease for obligatory declaration by... |
Aniline is a solvent used in dyes, antioxidants, rubber accelerators, drugs, photographic chemicals, isocyanates, herbicides, and fungicides . . Antidote methylene blue [figure 1] 12 mg should be started after 4 h of exposure as the symptoms or extent of toxicity of poisoning cannot be determined before that . Dependin... |
Chronic lymphocytic leukaemia (cll), the commonest type of leukaemia, is a generalised malignancy of lymphoid tissue originating in the bone marrow . It is characterised by an accumulation of monoclonal lymphocytes, usually of b cell type . The malignant lymphocytes spread from the bone marrow to blood, lymph nodes and... |
Pityriasis amiantacea (pa) is a scalp disorder presenting with thick, silvery / yellowish, asbestos - like scales wrapping around and binding down tufts of hair . It is typically considered to be a reactive condition to several inflammatory diseases, which may affect the scalp, mainly including psoriasis, atopic dermat... |
The world organization for animal health has identified ppr as a notifiable and economically important transboundary viral disease of sheep and goats associated with high morbidity and mortality . Clinically, symptoms of this disease include severe pyrexia, oculo - nasal discharges, necrotizing and erosive stomatitis, ... |
Today's technology makes it feasible to sequence the genome of almost any species of interest and to investigate complex genetic relationships in populations of animals [13]. However, the task of translating enormous amounts of genetic data into practical applications is still a work in progress [46]. As the ability to... |
It has been recognized that cardiac autonomic nervous system activity is of great significance in the initiation and maintenance of atrial fibrillation (af). Stimulation or inhibition of selective extracardiac neural structures may be a useful therapeutic option for cardiac arrhythmias, including af, and other abnormal... |
Blood - oxygen - level - dependent (bold) functional magnetic resonance imaging (fmri) is an imaging technique that makes it possible to dynamically and noninvasively track metabolic and hemodynamic changes in the brain [1, 2]. The early developments of bold fmri data analysis have mostly relied on a method called gene... |
Transfection of small interfering rna (sirna) molecules into mammalian cells induces post - transcriptional gene silencing via sequence - specific mrna degradation (rna interference) (1,2). Sirna molecules for rnai experiments can be generated by chemical or by enzymatic synthesis (1,3). Expressed hairpin molecules are... |
Previous studies showed that a novel, combined haemophilus influenzae type b (hib) and neisseria meningitidis serogroups c and y conjugate vaccine that uses tetanus toxoid as carrier protein (hibmency - tt) was immunogenic with an acceptable safety profile when administered to infants as a 3-dose primary series, with a... |
In the yoga sutras, yoga is defined as union of mind, body and spirit . These days it is assuming importance in improving mental health and quality of life in the treatment of a number of disorders . For example, a rash of psoriasis may not bother some people while it may make some feel depressed and more ill . For exa... |
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