Add dataset card

README.md

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+---
+license: cc-by-4.0
+task_categories:
+  - tabular-regression
+  - tabular-classification
+tags:
+  - gwas
+  - summary-statistics
+  - psychiatric-genomics
+  - pgc
+  - mdd
+  - mental-health
+  - genetics
+  - genomics
+pretty_name: >-
+  PGC Major Depressive Disorder GWAS Summary Statistics
+size_categories:
+  - 1M-10M
+configs:
+  - config_name: AntiDepResponse2021
+    default: true
+    data_files:
+      - split: train
+        path: data/AntiDepResponse2021/*.parquet
+  - config_name: mdd2013
+    data_files:
+      - split: train
+        path: data/mdd2013/*.parquet
+  - config_name: mdd2018
+    data_files:
+      - split: train
+        path: data/mdd2018/*.parquet
+  - config_name: mdd2018_noUKBB
+    data_files:
+      - split: train
+        path: data/mdd2018_noUKBB/*.parquet
+  - config_name: mdd2021asi
+    data_files:
+      - split: train
+        path: data/mdd2021asi/*.parquet
+  - config_name: mdd2023diverse
+    data_files:
+      - split: train
+        path: data/mdd2023diverse/*.parquet
+  - config_name: mdd2025
+    data_files:
+      - split: train
+        path: data/mdd2025/*.parquet
+  - config_name: ppd2023
+    data_files:
+      - split: train
+        path: data/ppd2023/*.parquet
+---
+
+# PGC Major Depressive Disorder — GWAS Summary Statistics
+
+[![License: CC BY 4.0](https://img.shields.io/badge/License-CC_BY_4.0-lightgrey)](https://creativecommons.org/licenses/by/4.0/)
+
+## Dataset Description
+
+Genome-wide association study (GWAS) summary statistics for **Major Depressive Disorder** phenotypes from the [Psychiatric Genomics Consortium (PGC)](https://pgc.unc.edu/).
+
+Each publication is available as a separate subset (config) and can be loaded independently.
+
+## Usage
+
+```python
+from datasets import load_dataset
+
+# Load a specific GWAS
+ds = load_dataset("OpenMed/pgc-mdd", "AntiDepResponse2021")
+print(ds)
+```
+
+### List all available subsets
+
+```python
+from datasets import get_dataset_config_names
+print(get_dataset_config_names("OpenMed/pgc-mdd"))
+```
+
+## Subsets
+
+| Config | Phenotype | Journal | Year | PubMed |
+|--------|-----------|---------|------|--------|
+| `AntiDepResponse2021` | Antidepressant Response | Biol Psychiatry: Global Open Science | 2021 | Pending |
+| `mdd2013` | Major Depression | Molecular Psychiatry | 2013 | [22472876](https://pubmed.ncbi.nlm.nih.gov/22472876/) |
+| `mdd2018` | Major Depression | Nature Genetics | 2018 | [29700475](https://pubmed.ncbi.nlm.nih.gov/29700475/) |
+| `mdd2018_noUKBB` | Major Depression (no UK Biobank) | Nature Genetics | 2018 | [29700475](https://pubmed.ncbi.nlm.nih.gov/29700475/) |
+| `mdd2021asi` | Major Depression (East Asian) | JAMA Psychiatry | 2021 | [34586374](https://pubmed.ncbi.nlm.nih.gov/34586374/) |
+| `mdd2023diverse` | Major Depression (Multi-Ancestry) | Nature Genetics | 2023 | [38177345](https://pubmed.ncbi.nlm.nih.gov/38177345/) |
+| `mdd2025` | Major Depression | Cell | 2025 | [39814019](https://pubmed.ncbi.nlm.nih.gov/39814019/) |
+| `ppd2023` | Peripartum Depression | American Journal of Psychiatry | 2023 | [37849304](https://pubmed.ncbi.nlm.nih.gov/37849304/) |
+
+## Data Format
+
+All data is stored as **Apache Parquet** shards (10,000 rows each). Common columns:
+
+| Column | Description |
+|--------|-------------|
+| `SNP` / `ID` | SNP rsID or variant identifier |
+| `CHR` | Chromosome |
+| `BP` / `POS` | Base-pair position (typically GRCh37/hg19) |
+| `A1` | Effect allele |
+| `A2` | Non-effect allele |
+| `OR` / `BETA` | Odds ratio or effect size |
+| `SE` | Standard error |
+| `P` | P-value |
+| `_source_file` | Original source filename |
+
+> Column names vary between publications. Check each subset's schema.
+
+## Citation
+
+Please cite the original publication (see PubMed links above) and acknowledge the PGC:
+
+> Data were obtained from the Psychiatric Genomics Consortium — https://pgc.unc.edu/
+
+## Terms of Use
+
+Released under **[CC BY 4.0](https://creativecommons.org/licenses/by/4.0/)** / **[CC0 1.0](https://creativecommons.org/publicdomain/zero/1.0/)**.
+
+- Cite the original publication(s)
+- Do not attempt to re-identify individual participants
+- Comply with the PGC [data use policies](https://pgc.unc.edu/for-researchers/data-access/)
+
+## Source
+
+- [Psychiatric Genomics Consortium (PGC)](https://pgc.unc.edu/)
+- [PGC Downloads](https://pgc.unc.edu/for-researchers/download-results/)