import torch from torch.utils.data import Dataset from typing import List, Dict, Any, Optional, Sequence, Tuple from pathlib import Path import pandas as pd DEFAULT_CONDITION_TOKENS: Tuple[str, ...] = ("", "", "") def split_condition_prefix( text: str, condition_tokens: Optional[Sequence[str]] = None, ) -> Tuple[str, str]: if not condition_tokens: return "", text remaining = text prefix_parts: List[str] = [] sorted_tokens = sorted({token for token in condition_tokens if token}, key=len, reverse=True) while remaining: matched = False for token in sorted_tokens: if remaining.startswith(token): prefix_parts.append(token) remaining = remaining[len(token):] matched = True break if not matched: break return "".join(prefix_parts), remaining def normalize_sequence_text( text: Any, uppercase: bool = True, strip: bool = True, conditioned_input: bool = False, condition_tokens: Optional[Sequence[str]] = None, ) -> str: value = "" if text is None else str(text) if strip: value = value.strip() if not value: return value if not conditioned_input: return value.upper() if uppercase else value prefix, dna_suffix = split_condition_prefix( value, condition_tokens=condition_tokens or DEFAULT_CONDITION_TOKENS, ) if uppercase: dna_suffix = dna_suffix.upper() return prefix + dna_suffix class ParquetSequenceDataset(Dataset): def __init__( self, parquet_path: str, sequence_col: str = "sequence", uppercase: bool = True, strip: bool = True, dropna: bool = True, limit: Optional[int] = None, conditioned_input: bool = False, condition_tokens: Optional[Sequence[str]] = None, ): if limit is not None and limit <= 0: raise ValueError("limit must be a positive integer.") p = Path(parquet_path) paths: List[Path] if p.is_dir(): paths = sorted(p.glob("*.parquet")) if not paths: raise FileNotFoundError(f"No parquet files under: {parquet_path}") else: if not p.exists(): raise FileNotFoundError(parquet_path) paths = [p] sequences: List[str] = [] remaining = limit for fp in paths: try: df = pd.read_parquet(fp, columns=[sequence_col]) except Exception as e: raise ValueError(f"Failed to read column '{sequence_col}' from {fp}: {e}") from e if dropna: df = df[df[sequence_col].notna()] s = df[sequence_col].astype(str) s = s.map( lambda value: normalize_sequence_text( text=value, uppercase=uppercase, strip=strip, conditioned_input=conditioned_input, condition_tokens=condition_tokens, ) ) if remaining is not None: if remaining <= 0: break s = s.iloc[:remaining] remaining -= len(s) sequences.extend(s.tolist()) if remaining is not None and remaining <= 0: break if not sequences: raise ValueError( "No sequences found after filtering. Check parquet_path and sequence_col." ) self.seqs = sequences def __len__(self): return len(self.seqs) def __getitem__(self, idx) -> Dict[str, Any]: return {"text": self.seqs[idx]} class SequenceDataCollator: def __init__( self, tokenizer, max_length: int = 16384, pad_to_multiple_of: Optional[int] = None, add_special_tokens: bool = True, # Let tokenizer add and conditioned_input: bool = False, condition_tokens: Optional[Sequence[str]] = None, ): self.tokenizer = tokenizer self.max_length = max_length self.pad_to_multiple_of = pad_to_multiple_of self.add_special_tokens = add_special_tokens self.conditioned_input = conditioned_input self.condition_tokens = tuple(condition_tokens or DEFAULT_CONDITION_TOKENS) # Ensure pad_token is set, even if the tokenizer doesn't register it. if self.tokenizer.pad_token is None: self.tokenizer.pad_token = "" def __call__(self, features: List[Dict[str, Any]]) -> Dict[str, torch.Tensor]: texts = [f["text"] for f in features] # Right-truncate to a multiple of tokenizer.k before tokenization. k = self.tokenizer.k if self.conditioned_input: processed_texts = [] for text in texts: prefix, dna_suffix = split_condition_prefix( text, condition_tokens=self.condition_tokens, ) usable_length = len(dna_suffix) - (len(dna_suffix) % k) processed_texts.append(prefix + dna_suffix[:usable_length]) texts = processed_texts else: texts = [t[:len(t) - (len(t) % k)] for t in texts] enc = self.tokenizer( texts, add_special_tokens=self.add_special_tokens, padding=True, truncation=True, max_length=self.max_length, return_tensors="pt", pad_to_multiple_of=self.pad_to_multiple_of, ) input_ids = enc["input_ids"] attention_mask = enc.get("attention_mask", torch.ones_like(input_ids)) labels = input_ids.clone() labels[attention_mask == 0] = -100 return { "input_ids": input_ids, "attention_mask": attention_mask, "labels": labels, }