README.md

---
license: cc-by-4.0
language:
- en
tags:
- clinical-trials
- biomedical
- pharma
- healthcare
- parquet
- phase3
pretty_name: Clinical Trials Phase 3 Intelligence
size_categories:
- 10K<n<100K
---
# clinicaltrials-completed-phase3-full — Data Card
**Version:** 1.1.0 | **Generated:** 2026-06-14T06:18:47.568731+00:00 | **Records:** 29,633

## Dataset Summary
**clinicaltrials-completed-phase3-full** contains structured clinical trial records from ClinicalTrials.gov, the U.S. federal registry of clinical studies operated by the National Library of Medicine (NIH). Each record includes trial status, design parameters, eligibility criteria, sponsor information, enrollment counts, and primary outcome measures — extracted, normalized, and validated by the jade pipeline. Intended for clinical researchers, pharmaceutical data teams, market intelligence analysts, and quantitative healthcare investors.

## Source
- **Primary source:** ClinicalTrials.gov, the U.S. National Library of Medicine's registry of clinical studies, operated by NIH. Accessed via the ClinicalTrials.gov REST API v2. Enrichment fields added post-hoc from the same source.
- **Collection method:** Automated pipeline using jade v0.1.0
- **License:** U.S. Government Open Data (Public Domain) — no restrictions on use or redistribution
- **PII status:** No personally identifiable information. Investigator contacts and
  patient-level data excluded at collection time.

## Quality Metrics
- **Dataset quality score:** 0.9867 (threshold: 0.92)
- **Validation layers:** Pydantic schema · Business rules · Statistical checks · LLM cross-check
- **Records passing validation:** 29,633 of 29,633 in this version

## Field Definitions
| Field | Type | Description |
|-------|------|-------------|
| nct_id | str | ClinicalTrials.gov unique identifier (NCT######) |
| title | str | Brief title of the clinical study |
| official_title | str | None | Full official title of the study |
| status | str | Overall recruitment status (e.g. COMPLETED, RECRUITING) |
| start_date | str | None | Study start date (YYYY-MM-DD) |
| completion_date | str | None | Primary completion date (YYYY-MM-DD) |
| sponsor_name | str | Lead sponsor organization name |
| sponsor_class | str | None | Sponsor classification (INDUSTRY, NIH, OTHER_GOV, etc.) |
| conditions | list[str] | Medical conditions or diseases studied |
| study_type | str | None | Study type: INTERVENTIONAL or OBSERVATIONAL |
| phases | list[str] | Clinical trial phases (e.g. PHASE3) |
| enrollment | int | None | Target or actual enrollment count |
| allocation | str | None | Allocation method: RANDOMIZED or NON_RANDOMIZED |
| masking | str | None | Blinding type (e.g. DOUBLE, OPEN_LABEL) |
| interventions | list[dict] | Interventions with type, name, and description |
| primary_outcomes | list[dict] | Primary outcome measures with measure and time_frame |
| secondary_outcomes | list[dict] | Secondary outcome measures with measure and time_frame |
| minimum_age | str | dict | None | Minimum participant age (parsed value and unit) |
| maximum_age | str | dict | None | Maximum participant age (parsed value and unit) |
| sex | str | None | Eligible sex: ALL, FEMALE, or MALE |
| results_available | bool | Whether results have been posted to ClinicalTrials.gov |
| locations_count | int | None | Number of study sites / locations |
| countries | list[str] | Countries where the study is conducted |
| trial_duration_days | int | None | Days from start_date to completion_date. Null if either date missing. |
| therapeutic_area | str | Disease area classification: Oncology, Cardiovascular, Neurology / CNS, Infectious Disease, Metabolic / Endocrine, Immunology / Rheumatology, Respiratory, Gastroenterology, Dermatology, Ophthalmology, Rare Disease / Orphan, Other. |
| primary_endpoint_met | str | Whether the primary endpoint was achieved: 'true', 'false', or 'unknown'. Coverage: ~45% of records (those with posted results on ClinicalTrials.gov). Extracted by LLM from the results section. |

## Known Limitations
- Location data (countries, locations_count) is absent for approximately 15% of studies where ClinicalTrials.gov omits the contactsLocationsModule.
- sponsor_class may include values outside the standard set (e.g. 'OTHER') for a small fraction of records; these receive a statistical soft warning but are not excluded.
- Completion dates reflect the study's reported anticipated or actual completion, not verified outcomes.
- Age fields (minimum_age, maximum_age) are returned as parsed {value, unit} objects rather than plain strings.
- primary_endpoint_met is 'unknown' for ~55% of records where ClinicalTrials.gov has not yet posted results. This is expected — results are posted voluntarily and often lag trial completion.
- therapeutic_area is LLM-assigned and may differ from formal MeSH classification for trials spanning multiple disease areas.

## Update Cadence
Weekly (every Friday night)

## Provenance
All records include a provenance object documenting:
- Source URL and retrieval timestamp
- Extraction model and pipeline version
- Validation model and quality score
- Whether LLM cross-check was performed

## License
This dataset is derived entirely from U.S. federal government public records
(ClinicalTrials.gov, operated by the National Library of Medicine, NIH).
The source data is in the public domain. This structured, cleaned version
is provided under CC BY 4.0 — attribution required.

## How to Access the Full Dataset

The 50-row `sample.csv` in this repository is free to use under CC BY 4.0.

**Full dataset (29,633 records, 26 fields, Parquet format):**
Available for purchase at [Ruby Intelligence on Gumroad](https://rubyintelligence.gumroad.com/l/hlgxox)

- One-time download: $1,499

---
*Generated by jade pipeline v0.1.0 · 2026-06-14T06:18:47.568731+00:00*