Datasets:
task3_SSL: add the no-LLM groups (policy-random runs; frozen DINOv3, DINO4Cells, DCM, OpenPhenom, Phenom, CellProfiler)
Browse files
README.md
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### `task3_SSL/` — self-supervised representation learning
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SHAPE-ES vs ReAct (at SHAPE-ES's control frequency), each with gpt-5.6-luna and claude-sonnet-5-5, against
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fixed-recipe
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(
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| archive | arm | HEPG2 | RPE | HUVEC |
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| `react_<task>_s0_luna` | ReAct · gpt-5.6-luna | 0.0116 | 0.0040 | 0.220 |
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| `react_<task>_s0_sonnet` | ReAct · claude-sonnet-5-5 | 0.0021 | 0.0151 | 0.260 |
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| `policy_fixed_<task>_s0` | fixed recipe, no LLM | 0.0137 | 0.0331 | 0.300 |
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| `default_<task>_s0` | default fine-tune | 0.0086 | 0.0198 | 0.262 |
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Each run archive holds the agent trace (`agent_log.jsonl`), every LLM request and reply (`reasoner.jsonl`), every
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tool call with its training record (`tool_calls.jsonl`), run settings, the delivered model's record, per-call loss
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curves, the console log and the score; no checkpoints.
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[SHAPE-Revision `repro-sweep`](https://github.com/xuekunwu/SHAPE-Revision/tree/repro-sweep/reproduce/sweep_2026_10).
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## Unpack
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### `task3_SSL/` — self-supervised representation learning
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SHAPE-ES vs ReAct (at SHAPE-ES's control frequency), each with gpt-5.6-luna and claude-sonnet-5-5, against no-LLM
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baselines: fixed-recipe and random searches over the same levers, the default DINOv3 fine-tune, and frozen pretrained
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models (DINOv3, DINO4Cells, DCM, OpenPhenom, Phenom, CellProfiler). Training used a 25 % subset of each plate's
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training wells (seed 0). Scores on held-out wells: RxRx1 well mAP (HEPG2, RPE), RxRx3-core EFAAR recall (HUVEC).
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| archive | arm | HEPG2 | RPE | HUVEC |
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|---|---|---|---|---|
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| `react_<task>_s0_luna` | ReAct · gpt-5.6-luna | 0.0116 | 0.0040 | 0.220 |
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| `react_<task>_s0_sonnet` | ReAct · claude-sonnet-5-5 | 0.0021 | 0.0151 | 0.260 |
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| `policy_fixed_<task>_s0` | fixed recipe, no LLM | 0.0137 | 0.0331 | 0.300 |
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| `policy_random_<task>_s0` | random search, no LLM | 0.0147 | 0.0380 | 0.287 |
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| `default_<task>_s0` | default fine-tune | 0.0086 | 0.0198 | 0.262 |
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| `frozen_models` | frozen DINOv3 | 0.0145 | 0.0237 | 0.293 |
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| `frozen_models` | frozen DINO4Cells-S / -B | 0.0150 / 0.0126 | 0.0295 / 0.0240 | 0.265 / 0.280 |
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| `frozen_models` | frozen DCM DINOv2-B | 0.0072 | 0.0168 | 0.268 |
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| `frozen_models` | frozen OpenPhenom | 0.0058 | 0.0090 | 0.267 |
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| `frozen_models` | Phenom-1 / Phenom-2 / CellProfiler (released tables) | — | — | 0.318 / 0.358 / 0.286 |
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Each run archive holds the agent trace (`agent_log.jsonl`), every LLM request and reply (`reasoner.jsonl`), every
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tool call with its training record (`tool_calls.jsonl`), run settings, the delivered model's record, per-call loss
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curves, the console log and the score; no checkpoints. Frozen models train nothing, so `frozen_models` holds their
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scores, scorer outputs and embedding code instead. Details: `logs/task3_SSL/README.md`. Code to rerun:
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[SHAPE-Revision `repro-sweep`](https://github.com/xuekunwu/SHAPE-Revision/tree/repro-sweep/reproduce/sweep_2026_10).
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## Unpack
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logs/task3_SSL/README.md
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- `react` — ReAct at SHAPE-ES's control frequency (a call resuming a finished call inherits its parameters; the
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learning rates change in at most one call per run);
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- `policy_fixed` — a fixed-recipe search over the same levers, no LLM;
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- `default` — the plain DINOv3 fine-tune at the tool's defaults, no LLM;
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- frozen
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LLM arms ran with gpt-5.6-luna (`_luna`) and claude-sonnet-5-5 (`_sonnet`), reasoning effort high.
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| ReAct · luna | 0.0116 | 0.0040 | 0.220 |
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| ReAct · Sonnet | 0.0021 | 0.0151 | 0.260 |
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| policy-fixed | 0.0137 | 0.0331 | 0.300 |
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| default fine-tune | 0.0086 | 0.0198 | 0.262 |
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| frozen DINOv3 | 0.0145 | 0.0237 | 0.293 |
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## Archives
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- `run/react/` (ReAct only) — the ReAct session trace;
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- `lane.log` — the run's console log; `score.json` — its held-out score.
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`default_<task>_s0.tar.zst` hold the control stage's `CONTROL.json` (training record of the default fine-tune and of
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frozen DINOv3), its console log and score. `summary.tar.zst`: `results.json` (every score, wall-clock hours, training
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hours, LLM tokens), the summary figure, frozen DINOv3's scores and `VALIDATION.md` (the reproduction code against the
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- `react` — ReAct at SHAPE-ES's control frequency (a call resuming a finished call inherits its parameters; the
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learning rates change in at most one call per run);
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- `policy_fixed` — a fixed-recipe search over the same levers, no LLM;
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- `policy_random` — a random search over the same levers, no LLM;
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- `default` — the plain DINOv3 fine-tune at the tool's defaults, no LLM;
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- frozen pretrained models, no training and so no trace: DINOv3 (the analyzer's starting point), DINO4Cells-S/B,
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DCM DINOv2-B, OpenPhenom, Phenom-1/2 and CellProfiler (`frozen_models.tar.zst`).
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LLM arms ran with gpt-5.6-luna (`_luna`) and claude-sonnet-5-5 (`_sonnet`), reasoning effort high.
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| ReAct · luna | 0.0116 | 0.0040 | 0.220 |
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| ReAct · Sonnet | 0.0021 | 0.0151 | 0.260 |
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| policy-fixed | 0.0137 | 0.0331 | 0.300 |
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| policy-random | 0.0147 | 0.0380 | 0.287 |
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| default fine-tune | 0.0086 | 0.0198 | 0.262 |
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| frozen DINOv3 | 0.0145 | 0.0237 | 0.293 |
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| frozen DINO4Cells-S (Cell Painting) | 0.0150 | 0.0295 | 0.265 |
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| frozen DINO4Cells-B (Cell Painting) | 0.0126 | 0.0240 | 0.280 |
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| frozen DCM DINOv2-B (JUMP-CP) | 0.0072 | 0.0168 | 0.268 |
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| frozen OpenPhenom (MAE-S) | 0.0058 | 0.0090 | 0.267 |
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| frozen Phenom-1 (MAE-L) | — | — | 0.318 |
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| frozen Phenom-2 (MAE-G) | — | — | 0.358 |
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| CellProfiler features | — | — | 0.286 |
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The 25 % subset changes only the training wells. Validation and held-out wells are the full prep's, so the frozen
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models' scores apply unchanged (frozen DINOv3 scores the same to the last digit on both preps). Phenom-1/2 and
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CellProfiler exist only as Recursion's released RxRx3-core tables, so they have no RxRx1 score. The summary figure
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(`summary.tar.zst`) shows the arms of the main comparison only, without policy-random and the frozen models other
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than DINOv3.
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## Archives
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- `run/react/` (ReAct only) — the ReAct session trace;
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- `lane.log` — the run's console log; `score.json` — its held-out score.
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`frozen_models.tar.zst`: the frozen pretrained models' scores (`scores.json`, with the per-plate matched table and
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per-source recall), their scorer outputs, and the embedding and EFAAR scoring code (see its `README.md`).
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`default_<task>_s0.tar.zst` hold the control stage's `CONTROL.json` (training record of the default fine-tune and of
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frozen DINOv3), its console log and score. `summary.tar.zst`: `results.json` (every score, wall-clock hours, training
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hours, LLM tokens), the summary figure, frozen DINOv3's scores and `VALIDATION.md` (the reproduction code against the
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logs/task3_SSL/frozen_models.tar.zst
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size 13926
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logs/task3_SSL/policy_random_HEPG2_s0.tar.zst
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logs/task3_SSL/policy_random_HUVEC_s0.tar.zst
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logs/task3_SSL/policy_random_RPE_s0.tar.zst
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logs/task3_SSL/summary.tar.zst
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