id stringlengths 6 42 | title stringlengths 3 499 | abstract stringlengths 0 6.24k | label listlengths 0 6 |
|---|---|---|---|
10.18632/oncotarget.19567 | The AF4-MLL fusion transiently augments multilineage hematopoietic engraftment but is not sufficient to initiate leukemia in cord blood CD34<sup>+</sup> cells | The translocation t(4;11)(q21;q23) is the hallmark genetic abnormality associated with infant pro-B acute lymphoblastic leukemia (B-ALL) and has the highest frequency of rearrangement in Mixed-lineage leukemia (MLL) leukemias. Unlike other MLL translocations, MLL-AF4-induced proB-ALL is exceptionally difficult to model... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Cell Biology, Development, Stem Cells and Regeneration",
"Integrative Biology: from Genes and Genomes to Systems"
] |
W2066478212 | Limits of hybrid political orders: the case of Somaliland | Abstract Hybrid political orders are in the literature discussed as a heuristic tool to understand how power and legitimacy are negotiated in settings where the Western model of the liberal democratic state does not work. Sometimes they are presented as an alternative model for successful statehood, e.g., by combining ... | [
"Institutions, Governance and Legal Systems",
"The Social World and Its Interactions"
] |
US 2021/0062204 W | DETOXIFICATION DEVICE HAVING HEATED FILTER FOR KILLING PATHOGENS | A detoxification device for removing pathogens from air within an environment. The detoxification device may include a filtration media for catching and retaining particles larger than about 0.3 micrometers (pm) with an efficiency of at least 99%, The detoxification device may also include a heating element having a me... | [
"Products and Processes Engineering",
"Materials Engineering"
] |
10.1039/C7CC04289B | Scavenger Templates A Systems Chemistry Approach To The Synthesis Of Porphyrin Based Molecular Wires | A hexa-pyridyl template can be used as a scavenger to facilitate the synthesis of a linear porphyrin dodecamer from a mixture of linear hexamers with one or two terminal reactive groups. The template suppresses polymer formation by rapidly cyclizing the fully deprotected hexamer, thus up-regulating formation of the lin... | [
"Synthetic Chemistry and Materials",
"Physical and Analytical Chemical Sciences"
] |
10.1111/ajps.12225 | Are Voters Equal under Proportional Representation? | We develop and apply a new conceptual framework and measure for evaluating electoral systems, focusing on (in)equality in parliamentary representation. Our main arena of interest is proportional representation with districts, an electoral system employed by more than half of democratic states, and we draw on an almost ... | [
"Institutions, Governance and Legal Systems",
"The Social World and Its Interactions"
] |
950262 | DEAD-box ATPases as master regulators of phase-separated compartments to control cellular RNA flux and the remodeling of RNA-protein complexes | Life ultimately depends on the tight control of gene expression, which requires an ordered and efficient processing of various RNA molecules. Messenger RNAs (mRNAs) – bound by a constantly changing coat of passenger proteins - transit from transcription in the nucleus to translation and ultimately decay in the cytoplas... | [
"Cell Biology, Development, Stem Cells and Regeneration",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.3389/fimmu.2019.01462 | The metabolic signature of macrophage responses | Macrophages are a heterogeneous population of immune cells playing several and diverse functions in homeostatic and immune responses. The broad spectrum of macrophage functions depends on both heterogeneity and plasticity of these cells, which are highly specialized in sensing the microenvironment and modify their prop... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1007/s10670-019-00128-z | The Logic of Fast and Slow Thinking | AbstractWe present a framework for epistemic logic, modeling the logical aspects of System 1 (“fast”) and System 2 (“slow”) cognitive processes, as per dual process theories of reasoning. The framework combines non-normal worlds semantics with the techniques of Dynamic Epistemic Logic. It models non-logically-omniscien... | [
"The Human Mind and Its Complexity",
"Computer Science and Informatics"
] |
10.1080/15476286.2016.1142039 | Bidirectional Coupling Of Splicing And Atm Signaling In Response To Transcription Blocking Dna Damage | In response to DNA damage cells activate intricate protein networks to ensure genomic fidelity and tissue homeostasis. DNA damage response signaling pathways coordinate these networks and determine cellular fates, in part, by modulating RNA metabolism. Here we discuss a replication-independent pathway activated by tran... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems",
"Cell Biology, Development, Stem Cells and Regeneration"
] |
10.1088/1748-9326/ab8589 | Quantifying the potential for climate change mitigation of consumption options | Background. Around two-thirds of global GHG emissions are directly and indirectly linked to household consumption, with a global average of about 6 tCO2eq/cap. The average per capita carbon footprint of North America and Europe amount to 13. 4 and 7. 5 tCO2eq/cap, respectively, while that of Africa and the Middle East ... | [
"Environmental Biology, Ecology and Evolution",
"Earth System Science"
] |
10.1109/SEAA.2012.11 | Engineering Emergent Semantics Into Pervasive Resource Discovery | Pervasive environments are composed as spontaneous aggregation of heterogeneous and independent devices, which may seamlessly consume, but also provide, software resources over the network. As result, applications emerge from the dynamic composition of the resources available within the environment. This requires appli... | [
"Computer Science and Informatics",
"Systems and Communication Engineering"
] |
W1997148938 | Hybrid general-purpose computation on GPU (GPGPU) and computer graphics synthetic aperture radar simulation for complex scenes | In this paper, a new hybrid general-purpose computation on GPU (GPGPU) and computer graphics synthetic aperture radar (SAR) simulation method for complex scenes is proposed. Previous SAR simulations for complex scenes only use GPU’s graphics capabilities for scattering calculation in graphical electromagnetic computing... | [
"Computer Science and Informatics",
"Systems and Communication Engineering"
] |
10.1002/anie.201603562 | Structural Analysis using SHALiPE to Reveal RNA G-Quadruplex Formation in Human Precursor MicroRNA | RNA G-quadruplex (rG4) structures are of fundamental importance to biology. A novel approach is introduced to detect and structurally map rG4s at single-nucleotide resolution in RNAs. The approach, denoted SHALiPE, couples selective 2′-hydroxyl acylation with lithium ion-based primer extension, and identifies character... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems",
"Physical and Analytical Chemical Sciences"
] |
10.1016/j.annepidem.2013.05.014 | Time away from work predicts later cognitive function: Differences by activity during leave | Purpose: We sought to examine how different activities performed during employment gaps are associated with later cognitive function and change. Methods: Five cognitive measures were used to indicate cognitive impairment of 18,259 respondents to the Survey of Health, Ageing, and Retirement in Europe (ages 50-73) in 200... | [
"The Human Mind and Its Complexity",
"The Social World and Its Interactions",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
W2149278034 | Evaluation of Sustainability of Smallholder Dairy Production Systems in the Highlands of Mexico During the Rainy Season | A sustainability evaluation was undertaken with 22 smallholder dairy farms in the highlands of Mexico; following the IDEA method in the agroecological, socioterritorial, and economic scales (all scales are out of 100). Sustainability was highest for the agroecological scale (59/100), intermediate for the socioterritori... | [
"Earth System Science",
"Human Mobility, Environment, and Space",
"Individuals, Markets and Organisations"
] |
10.1007/s11229-016-1202-1 | On the supposed connection between proper names and singular thought | A thesis I call the name-based singular thought thesis (NBT thesis) is part of orthodoxy in contemporary philosophy of mind and language: it holds that taking part in communication involving a proper name puts one in a position to entertain singular thoughts about the name’s referent. I argue, first, that proponents of... | [
"Texts and Concepts",
"The Human Mind and Its Complexity"
] |
883275 | A diagnostic tool for endometritis in cows, based on a portable automated image recognition software | Endometritis is a curable uterine infection that is highly prevalent in cow farms affecting approximately 30% of cows per year, with up to 70% incidence in some herds. A farm with just 1,500 cows and with a typical incidence rate of 30% has a loss of up to €146,000 a year due to the costs associated with endometritis. ... | [
"Products and Processes Engineering",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1111/cobi.12462 | Quantifying the erosion of natural darkness in the global protected area system | The nighttime light environment of much of the earth has been transformed by the introduction of electric lighting. This impact continues to spread with growth in the human population and extent of urbanization. This has profound consequences for organismal physiology and behavior and affects abundances and distributio... | [
"Environmental Biology, Ecology and Evolution",
"Earth System Science"
] |
10.1016/j.bbamcr.2008.05.013 | Prohibitin function within mitochondria: Essential roles for cell proliferation and cristae morphogenesis | Prohibitins comprise an evolutionary conserved and ubiquitously expressed family of membrane proteins. Various roles in different cellular compartments have been proposed for prohibitin proteins. Recent experiments, however, identify large assemblies of two homologous prohibitin subunits, PHB1 and PHB2, in the inner me... | [
"Cell Biology, Development, Stem Cells and Regeneration",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
W1631012431 | Fair Trade and justice: a comment on Walton and Deneulin | In this article we first point out that the different conceptualisations of Fair Trade, which are sometimes analytically contradictory, actually form a coordinated set. Understanding the Fair Trade project is impossible without taking these interlinked conceptualisations into consideration. Second, this set basically f... | [
"Texts and Concepts",
"Institutions, Governance and Legal Systems",
"The Social World and Its Interactions"
] |
171358 | Inorganic therapeutic nanoparticles for osteoporosis | The aim of the proposed interdisciplinary project is to design, make and test novel nanoparticles that will have direct and rapid impact in osteoporosis. The unique aspect of these injectable nanoparticles is that they will deliver active therapy locally, to where it is needed, and that the cargo is not a conventional ... | [
"Physiology in Health, Disease and Ageing",
"Prevention, Diagnosis and Treatment of Human Diseases",
"Materials Engineering"
] |
W2466691842 | Molybdenum-99-producing 37-element fuel bundle neutronically and thermal-hydraulically equivalent to a standard CANDU fuel bundle | Abstract 99m Tc, the most commonly used radioisotope in diagnostic nuclear medicine, results from the radioactive decay of 99 Mo which is currently being produced at various research reactors around the globe. In this study, the potential use of CANDU power reactors for the production of 99 Mo is investigated. A modifi... | [
"Products and Processes Engineering",
"Fundamental Constituents of Matter",
"Materials Engineering"
] |
W2598552155 | Modelling of Consequences of Biogas Leakage from Gasholder | This paper describes modelling of consequences of biogas leakage from a gasholder on agricultural biogas station. Four scenarios were selected for the purpose of this work. A rupture of gasholders membrane and instantaneous explosion of gas cloud, blast of gas with delay, emptying of whole volume of gas (without initia... | [
"Products and Processes Engineering",
"Physical and Analytical Chemical Sciences",
"Systems and Communication Engineering"
] |
3732344 | Micro-Scale dependent, time- and space-evolving rheologies: the key for generating strain localization in the earth | RhEoVOLUTION proposes a ""revolution"" in how we define rheology (the equations relating forces to deformation) in geodynamical models. It aims at predicting the onset and evolution of strain localization. Modeling spontaneous ductile strain localization has been impossible so far, because it depends on processes activ... | [
"Earth System Science",
"Condensed Matter Physics",
"Computer Science and Informatics"
] |
291156 | Flow Machines: Interacting with Style | Content creation is a fundamental activity for developing identities in modern individuals. Yet creativity is hardly addressed by computer science. This project addresses the issue of content creation from the perspective of Flow machines. Flow machines are interactive systems that learn how to generate content, text o... | [
"Computer Science and Informatics",
"The Human Mind and Its Complexity"
] |
10.1042/bj20102090 | Substrate diffusion and oxidation in GMC oxidoreductases: an experimental and computational study on fungal aryl-alcohol oxidase | AAO (aryl-alcohol oxidase) provides H2O2 in fungal degradation of lignin, a process of high biotechnological interest. The crystal structure of AAO does not show open access to the active site, where different aromatic alcohols are oxidized. In the present study we investigated substrate diffusion and oxidation in AAO ... | [
"Physical and Analytical Chemical Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1073/pnas.1421056111 | Place cells in the hippocampus: Eleven maps for eleven rooms | The contribution of hippocampal circuits to high-capacity episodic memory is often attributed to the large number of orthogonal activity patterns that may be stored in these networks. Evidence for high-capacity storage in the hippocampus is missing, however. When animals are tested in pairs of environments, different c... | [
"Neuroscience and Disorders of the Nervous System"
] |
10.1016/j.yexcr.2014.07.013 | Sirtuin 6 protects the heart from hypoxic damage | Sirtuin 6 (SIRT6) is a protein associated with prolonged life expectancy. We investigated whether life extension is associated with cardioprotection against hypoxia. The proposed study is to develop approaches to reduce hypoxic damage through the use of the sirtuin pathway and to elucidate the mechanism involved. For t... | [
"Physiology in Health, Disease and Ageing",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.15252/emmm.201708076 | An oligoclonal antibody durably overcomes resistance of lung cancer to third-generation EGFR inhibitors | Epidermal growth factor receptor (EGFR) mutations identify patients with lung cancer who derive benefit from kinase inhibitors. However, most patients eventually develop resistance, primarily due to the T790M second-site mutation. Irreversible inhibitors (e. g. , osimertinib/AZD9291) inhibit T790M-EGFR, but several mec... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1007/s11229-013-0275-3 | Dynamics of lying | We propose a dynamic logic of lying, wherein a 'lie that φ' (where φ is a formula in the logic) is an action in the sense of dynamic modal logic, that is interpreted as a state transformer relative to the formula φ. The states that are being transformed are pointed Kripke models encoding the uncertainty of agents about... | [
"Computer Science and Informatics",
"The Human Mind and Its Complexity"
] |
W1600326538 | Mycobacterium tuberculosis employs Cpn60.2 as an adhesin that binds CD43 on the macrophage surface | CD43 is a large sialylated glycoprotein found on the surface of haematopoietic cells and has been previously shown to be necessary for efficient macrophage binding and immunological responsiveness to Mycobacterium tuberculosis. Using capsular material from M. tuberculosis and recombinant CD43-Fc, we have employed affin... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
W2013102540 | Craniofacial morphology characteristics of operated unilateral complete cleft lip and palate patients in mixed dentition | The objective of this study was to analyze craniofacial morphologic characteristics at the stage of mixed dentition in Chinese children who had received surgery for unilateral complete cleft lip and palate (UCCLP) compared with the healthy population.Lateral cephalometric radiographs were taken for 2 groups of individu... | [
"Physiology in Health, Disease and Ageing",
"Cell Biology, Development, Stem Cells and Regeneration"
] |
W2022311890 | Maintenance of belt conveyors using an expert system based on fuzzy logic | In recent years, conveyor belt transport systems have taken on a new significance due to numerous research studies on innovative design solutions. The application of these new developed solutions leads to considerable reduction in operational costs of transport systems, while ensuring their high reliability and service... | [
"Products and Processes Engineering",
"Computer Science and Informatics"
] |
10.1007/s11538-016-0194-9 | Numerical Bifurcation Analysis of Physiologically Structured Populations: Consumer–Resource, Cannibalistic and Trophic Models | With the aim of applying numerical methods, we develop a formalism for physiologically structured population models in a new generality that includes consumer–resource, cannibalism and trophic models. The dynamics at the population level are formulated as a system of Volterra functional equations coupled to ODE. For th... | [
"Mathematics",
"Environmental Biology, Ecology and Evolution"
] |
10.1145/2746539.2746620 | From Independence To Expansion And Back Again | We consider the following fundamental problems: Constructing k-independent hash functions with a space-time tradeoff close to Siegel's lower bound. Constructing representations of unbalanced expander graphs having small size and allowing fast computation of the neighbor function. It is not hard to show that these probl... | [
"Computer Science and Informatics",
"Mathematics"
] |
W1985816518 | Evaluation of the vectorial capacity of Rhipicephalus sanguineus (Acari: Ixodidae) in the transmission of canine visceral leishmaniasis | The vectorial capacity of Rhipicephalus sanguineus in the transmission of canine visceral leishmaniasis has been evaluated through a laboratory-controlled experiment. One healthy Leishmania-free dog and two dogs naturally infected with Leishmania were infested with R. sanguineus in various stages of development. Engorg... | [
"Immunity, Infection and Immunotherapy",
"Environmental Biology, Ecology and Evolution"
] |
10.1093/jxb/eru161 | Reticulate evolution in Panicum (Poaceae): The origin of tetraploid broomcorn millet, P. miliaceum | Panicum miliaceum (broomcorn millet) is a tetraploid cereal, which was among the first domesticated crops, but is now a minor crop despite its high water use efficiency. The ancestors of this species have not been determined; we aimed to identify likely candidates within the genus, where phylogenies are poorly resolved... | [
"Environmental Biology, Ecology and Evolution",
"Integrative Biology: from Genes and Genomes to Systems",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
643610 | Neural, computational and acoustic principles of auditory sensory processing sensitivity | Hearing is an essential part of human life. We communicate through the voice, use sounds to navigate in the world and enjoy listening to music. On the other hand noise pollution in living and working environments causes serious health problems impacting millions of people and many neurological or psychiatric conditions... | [
"Neuroscience and Disorders of the Nervous System",
"Computer Science and Informatics",
"The Human Mind and Its Complexity"
] |
637853 | Injectable anisotropic microgel-in-hydrogel matrices for spinal cord repair | This project will engineer an injectable biomaterial that forms an anisotropic microheterogeneous structure in vivo. Injectable hydrogels enable a minimal invasive in situ generation of matrices for the regeneration of tissues and organs, but currently lack structural organization and unidirectional orientation. The an... | [
"Materials Engineering",
"Cell Biology, Development, Stem Cells and Regeneration",
"Neuroscience and Disorders of the Nervous System",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
268648 | Next Generation Genetics of Cancer Predisposition | Unravelling genetic components of human tumor predisposition has contributed significantly to our understanding on molecular basis of cancer, and cancer prevention in the context of hereditary tumor susceptibility is one of the early examples of benefits from genetic disease information. Research into cancer susceptibi... | [
"Integrative Biology: from Genes and Genomes to Systems",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1038/nsmb.1905 | The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA | Individuals with BRCA2 mutations are predisposed to breast cancers owing to genome instability. To determine the functions of BRCA2, the human protein was purified. It was found to bind selectively to single-stranded DNA (ssDNA), and to ssDNA in tailed duplexes and replication fork structures. Monomeric and dimeric for... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1007/JHEP12(2018)078 | Holographic Compact Stars Meet Gravitational Wave Constraints | We investigate a simple holographic model for cold and dense deconfined QCD matter consisting of three quark flavors. Varying the single free parameter of the model and utilizing a Chiral Effective Theory equation of state (EoS) for nuclear matter, we find four different compact star solutions: traditional neutron star... | [
"Fundamental Constituents of Matter",
"Universe Sciences"
] |
W2117547260 | On Newton’s method and Halley’s method for the principal <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si1.gif" overflow="scroll"><mml:mrow><mml:mi>p</mml:mi></mml:mrow></mml:math>th root of a matrix | If A is a matrix with no negative real eigenvalues and all zero eigenvalues of A are semisimple, the principal p th root of A can be computed by Newton’s method or Halley’s method, with a preprocessing procedure if necessary. We prove a new convergence result for Newton’s method, and discover an interesting property of... | [
"Mathematics"
] |
10.1063/1.4945792 | Energy Utilization In Fluctuating Biological Energy Converters | We have argued previously [Szoke et al. , FEBS Lett. 553, 18–20 (2003); Curr. Chem. Biol. 1, 53–57 (2007)] that energy utilization and evolution are emergent properties based on a small number of established laws of physics and chemistry. The relevant laws constitute a framework for biology on a level intermediate betw... | [
"Physical and Analytical Chemical Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1016/j.atmosenv.2008.10.059 | Deposition rates on smooth surfaces and coagulation of aerosol particles inside a test chamber | Because aerosol particle deposition is an important factor in indoor air quality, many empirical and theoretical studies have attempted to understand the process. In this study, we estimated the deposition rate of aerosol particles on smooth aluminum surfaces inside a test chamber. We investigated the influence of turb... | [
"Physical and Analytical Chemical Sciences",
"Earth System Science"
] |
10.1002/jgrd.50828 | Gas-particle partitioning of primary organic aerosol emissions: 3. Biomass burning | Atmospheric organic aerosol concentrations depend in part on the gas-particle partitioning of primary organic aerosol (POA) emissions. Consequently, heating and dilution were used to investigate the volatility of biomass-burning smoke particles from combustion of common North American trees/shrubs/grasses during the th... | [
"Physical and Analytical Chemical Sciences",
"Earth System Science"
] |
169593 | European holocaust research infrastructure | The European Holocaust Research Infrastructure (EHRI) project seeks to transform archival research on the Holocaust. The vision of EHRI is to integrate the data, services and expertise of existing Holocaust infrastructures on an unprecedented scale. It will allow researchers from across the globe transnational and virt... | [
"The Study of the Human Past",
"Computer Science and Informatics"
] |
865724 | NanophononIcs for QUantum information procEssing | Over the past thirty years, the remarkable technological advances in microfabrication processes have thrust mechanical vibrations into the quantum realm. The intrinsic coherence of mechanical motion and the capability to couple it to other physical degrees of freedom hold promises of scalable hybrid quantum platforms. ... | [
"Condensed Matter Physics",
"Fundamental Constituents of Matter",
"Systems and Communication Engineering"
] |
10.1002/pssr.201105247 | Electronics with and on paper | Today there is a strong interest in the scientific and industrial community concerning the use of biopolymers for electronic applications, driven mainly by low-cost and disposable applications. Adding to this interest, we must recognise the importance of the dream of wireless auto-sustained and low-energy-consumption e... | [
"Systems and Communication Engineering",
"Materials Engineering"
] |
W4313194398 | Spiel im Morgengrauen (1926/1927) | 27 Jahre nach der Publikation von Lieutenant Gustl (1900) erscheint Schnitzlers zweite »Leutn[ants]novella « (Tb, 5.3.1924), Spiel im Morgengrauen, bei S. Fischer in Berlin. Der Entstehungsprozess der Novelle, die sich zugleich als Abwandlung und Aktualisierung früher Figuren und Grundmotive lesen lässt (vgl. Rey 1968,... | [
"Texts and Concepts"
] |
W3100010313 | MAGNETOSPHERIC ACCRETION AND EJECTION OF MATTER IN RESISTIVE MAGNETOHYDRODYNAMIC SIMULATIONS | The ejection of matter in the close vicinity of a young stellar object is investigated, treating the accretion disk as a gravitationally bound reservoir of matter. By solving the resistive MHD equations in 2D axisymmetry using our version of the Zeus-3D code with newly implemented resistivity, we study the effect of ma... | [
"Universe Sciences",
"Fundamental Constituents of Matter"
] |
320651 | Solving High Energy Physics Equations using Monte Carlo Gaming Techniques | The main objective of this proposal is to perform (hitherto unsolved) calculations in Quantum Field Theory (QFT) most of which are urgently needed to make optimal use of upcoming experimental data from the Large Hadron Collider. These specific calculations have been intractable thus far due to their enormous demand of ... | [
"Fundamental Constituents of Matter",
"Computer Science and Informatics"
] |
10.1016/j.msea.2015.08.060 | Effect of grain size and specimen dimensions on micro-forming of high purity aluminum | Micro-compression testing was conducted using high purity Al processed by equal-channel angular pressing (ECAP) with both coarse-grained (CG) and ultrafine-grained (UFG) samples. The effects on the flow stresses of the initial grain size and the specimen size were investigated and the results show the initial grain siz... | [
"Condensed Matter Physics",
"Materials Engineering"
] |
10.1007/s11229-013-0261-9 | A slugfest of intuitions: Contextualism and experimental design | This paper considers ways that experimental design can affect judgments about informally presented context shifting experiments. Reasons are given to think that judgments about informal context shifting experiments are affected by an exclusive reliance on binary truth value judgments and by experimenter bias. Exclusive... | [
"The Human Mind and Its Complexity"
] |
10.1209/0295-5075/122/36006 | Hydrogel Menisci Shape Interaction And Instability | The interface of a soft hydrogel is easily deformed when it is in contact with particles, droplets or cells. Here we compute the intricate shapes of hydrogel menisci due to the indentation of point particles. The analysis is based on a free energy formulation, by which we also assess the interaction laws between neighb... | [
"Condensed Matter Physics",
"Physical and Analytical Chemical Sciences"
] |
10.1126/science.aal3298 | Recent natural selection causes adaptive evolution of an avian polygenic trait | We used extensive data froma long-term study of great tits (Parusmajor) in theUnitedKingdom and Netherlands to better understand how genetic signatures of selection translate into variation in fitness and phenotypes. We found that genomic regions under differential selection contained candidate genes for bill morpholog... | [
"Environmental Biology, Ecology and Evolution",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1051/0004-6361/201937247 | ALMA chemical survey of disk-outflow sources in Taurus (ALMA-DOT) | The chemical composition of planets is determined by the distribution of the various molecular species in the protoplanetary disk at the time of their formation. To date, only a handful of disks have been imaged in multiple spectral lines with high spatial resolution. As part of a small campaign devoted to the chemical... | [
"Physical and Analytical Chemical Sciences",
"Universe Sciences"
] |
802437 | The Dark Side of Translation: 20th and 21st Century Translation from Russian as a Political Phenomenon in the UK, Ireland, and the USA | What is the dark side of translation? Translation is valued, taught, and often funded as a deterrent to monolingual nationalism and cultural parochialism. Yet the praxis of translation is highly politicized, often subverted by ideological prejudice or state interference. Translators have a personal agenda, as do editor... | [
"Texts and Concepts",
"The Study of the Human Past",
"Studies of Cultures and Arts"
] |
10.1371/journal.pone.0135353 | Lack of dietary polyunsaturated fatty acids causes synapse dysfunction in the Drosophila visual system | Polyunsaturated fatty acids (PUFAs) are essential nutrients for animals and necessary for the normal functioning of the nervous system. A lack of PUFAs can result from the consumption of a deficient diet or genetic factors, which impact PUFA uptake and metabolism. Both can cause synaptic dysfunction, which is associate... | [
"Neuroscience and Disorders of the Nervous System",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Physiology in Health, Disease and Ageing"
] |
W4301394117 | USO DO PLASMA ATMOSFÉRICO A FRIO NO TRATAMENTO DO CARCINOMA DE CÉLULAS ESCAMOSAS FELINO EM ESTÁGIO AVANÇADO | INTRODUÇÃO: O plasma atmosférico frio (CAP) vem emergindo como tratamento promissor para o tratamento de lesões cutâneas, possuindo capacidade antimicrobiana e antinflamatória. Recentemente vem sendo utilizado no tratamento de neoplasias, promovendo a morte seletiva de células cancerígenas por meio da produção de espéc... | [
"Physiology in Health, Disease and Ageing",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1111/bjir.12053 | Rule Enactment in a Pan-European Labour Market: Transnational Posted Work in the German Construction Sector | This article analyses the micro-level rule enactment of the posting of workers framework in the German construction sector. I examine how actors draw on different power resources in order to influence policies without formal negotiation within transnational workspaces and thereby initiate institutional change. Drawing ... | [
"Institutions, Governance and Legal Systems",
"The Social World and Its Interactions"
] |
323883 | Personal Perception | The project aims to open-up a new research field concerned with how human visual perception operates in a social context, and involves an innovative link between cognitive and social psychology. In particular, the project assesses how personal social interests permeate the functional and neural processes supporting hum... | [
"The Social World and Its Interactions",
"The Human Mind and Its Complexity"
] |
US 2004/0005096 W | COVALENT MODIFICATION OF RNA FOR IN VITRO AND IN VIVO DELIVERY | The post-synthetic modification of RNA for the delivery of the RNA to a mammalian cell is described. The modifications enhance resistant of the RNA to nuclease digestion and delivery of the RNA to the cell whether the RNA is delivered alone or in combination with a transfection agent. Activity of the RNA in the cell is... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Biotechnology and Biosystems Engineering"
] |
10.1093/gbe/evt205 | Is ftsH the key to plastid longevity in sacoglossan slugs? | Plastids sequestered by sacoglossan sea slugs have long been a puzzle. Some sacoglossans feed on siphonaceous algae and can retain the plastids in the cytosol of their digestive gland cells. There, the stolen plastids (kleptoplasts) can remain photosynthetically active in some cases for months. Kleptoplast longevity it... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Environmental Biology, Ecology and Evolution",
"Integrative Biology: from Genes and Genomes to Systems"
] |
10.1016/j.gca.2014.06.037 | Structure, equation of state and transport properties of molten calcium carbonate (CaCO<inf>3</inf>) by atomistic simulations | First-principle molecular dynamics (FPMD) calculations have been performed to evaluate the physical properties of liquid calcium carbonate (CaCO3), which are up to now poorly known. The liquid structure, the density, the atomic vibration motions, the diffusion coefficients of calcium and carbonate ions and the electric... | [
"Condensed Matter Physics",
"Physical and Analytical Chemical Sciences"
] |
10.1080/17531055.2020.1768468 | One Stop Border Posts In East Africa State Encounters Of The Fourth Kind | Across Africa, One-Stop Border Posts are being rolled out as part of a continental/ regional integration agenda that seeks to facilitate the movement of people and goods. This article focuses on fo. . . | [
"Human Mobility, Environment, and Space",
"Institutions, Governance and Legal Systems"
] |
267104 | Towards the Construction of the Fundamental Theory of Flavour | Six quarks and six leptons of different kinds, referred to as flavours, form the modern periodic table of the fundamental building blocks of matter. The Standard Model of particle physics successfully describes these elementary particles and the forces between them. A deeper understanding of the flavour structure of qu... | [
"Fundamental Constituents of Matter"
] |
10.1039/c7ta03144k | Correlating photovoltaic properties of a PTB7-Th:PC71BM blend to photophysics and microstructure as a function of thermal annealing | The effect of thermal annealing on a polymer solar cell is investigated and related to changes in the photophysics and structure. | [
"Condensed Matter Physics",
"Physical and Analytical Chemical Sciences",
"Synthetic Chemistry and Materials"
] |
10.1093/cercor/bhs142 | Functional neural plasticity and associated changes in positive affect after compassion training | The development of social emotions such as compassion is crucial for successful social interactions as well as for the maintenance of mental and physical health, especially when confronted with distressing life events. Yet, the neural mechanisms supporting the training of these emotions are poorly understood. To study ... | [
"Neuroscience and Disorders of the Nervous System",
"The Human Mind and Its Complexity"
] |
10.1103/PhysRevC.86.035801 | Investigation of α-induced reactions on 127I for the astrophysical γ process | Background: The γ process in core-collapse supernova explosions is thought to explain the origin of proton-rich isotopes between Se and Hg, the so-called p nuclei. The majority of the reaction rates for γ process reaction network studies has to be predicted in Hauser-Feshbach statistical model calculations. Recent inve... | [
"Fundamental Constituents of Matter",
"Universe Sciences"
] |
10.1021/acs.chemmater.5b03995 | Controlled Shape and Nucleation Switching of Interfacially Polymerizable Nanoassemblies by Methyl Substitution | Interfacial polymerization of uniform template-free nanostructures is very challenging since many factors play determinant roles in the final structure of the resulting nanoassemblies. Here, we present a single oxidative coupling method for the synthesis of different nanoshapes by addition or substitution of a methyl g... | [
"Physical and Analytical Chemical Sciences",
"Materials Engineering",
"Synthetic Chemistry and Materials"
] |
10.1021/jacs.6b03604 | Advancing Drug Formulation Additives toward Precision Additives with Release Mediating Peptide Interlayer | Amphiphilic drug formulation additives based on palmitic acid-modified poly(ethylene glycol) (Pal-PEG) are combined with a tailored drug binding peptide that is positioned at the hydrophobic-hydrophilic interface. The peptide originates from combinatorial selection and enables precise modulation of the drug release pro... | [
"Physical and Analytical Chemical Sciences",
"Synthetic Chemistry and Materials",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1111/pai.12344 | Maternal preeclampsia and childhood asthma in the offspring | Background: Preeclampsia is a possible risk factor for childhood asthma in the offspring. Our aim was to find whether preeclampsia is associated with childhood asthma. We also aimed to study whether a possible association can be explained by factors shared by siblings. Methods: All eligible live singletons born in Denm... | [
"Prevention, Diagnosis and Treatment of Human Diseases",
"Physiology in Health, Disease and Ageing"
] |
Q77907 | Development of the Cybersecurity System of Internet Services as a tool to improve the security of use of Internet services by end-users. | Reference number of the aid programme: SA.41471(2015/X) Purpose of public aid: Article 25 of EC Regulation No 651/2014 of 17 June 2014 declaring certain types of aid compatible with the internal market in the application of Articles 107 and 108 of the Treaty (OJ L. I'm sorry. EU L 187/1 of 26.06.2014). The aim of the p... | [
"Computer Science and Informatics",
"Systems and Communication Engineering"
] |
10.1051/0004-6361/201834489 | Formation Of Planetary Systems By Pebble Accretion And Migration Growth Of Gas Giants | Giant planets migrate though the protoplanetary disc as they grow. We investigate how the formation of planetary systems depends on the radial flux of pebbles through the protoplanetary disc and on the planet migration rate. Our N-body simulations confirm previous findings that Jupiter-like planets in orbits outside th... | [
"Universe Sciences"
] |
10.1007/JHEP04(2015)019 | Holographic Charge Oscillations | The Reissner-Nordstrom black hole provides the prototypical description of a holographic system at finite density. We study the response of this system to the presence of a local, charged impurity. Below a critical temperature, the induced charge density, which screens the impurity, exhibits oscillations. These oscilla... | [
"Condensed Matter Physics",
"Fundamental Constituents of Matter"
] |
10.1037/a0025659 | Automated gaze-contingent objects elicit orientation following in 8-month-old infants | The current study tested whether the purely amodal cue of contingency elicits orientation following behavior in 8-month-old infants. We presented 8-month-old infants with automated objects without human features that did or did not react contingently to the infants' fixations recorded by an eye tracker. We found that a... | [
"Neuroscience and Disorders of the Nervous System",
"The Human Mind and Its Complexity"
] |
W2896274961 | Design and Operation Overview of 4-person 180-day Integrated Experiment in Controlled Ecological Life Support System | Objective To explore the key technologies of integrated bio-regenerative and physical-chemical regenerative life support system,and investigate the performance of the Controlled Ecological Life Support System( CELSS) with multiple crews in long-term experiment,and to meet the engineering demands of life support system ... | [
"Products and Processes Engineering",
"Biotechnology and Biosystems Engineering",
"Earth System Science"
] |
10.1016/j.celrep.2016.11.012 | Tenascin-C Orchestrates Glioblastoma Angiogenesis by Modulation of Pro- and Anti-angiogenic Signaling | High expression of the extracellular matrix component tenascin-C in the tumor microenvironment correlates with decreased patient survival. Tenascin-C promotes cancer progression and a disrupted tumor vasculature through an unclear mechanism. Here, we examine the angiomodulatory role of tenascin-C. We find that direct ... | [
"Cell Biology, Development, Stem Cells and Regeneration",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Physiology in Health, Disease and Ageing"
] |
10.1016/j.lingua.2015.10.002 | Pyow-hack revisited: Two analyses of Putty-nosed monkey alarm calls | Male Putty-nosed monkeys have two main alarm calls, pyows and hacks. While pyows have a broad distribution suggestive of a general call, hacks are often indicative of eagles. In a series of articles, Arnold and Zuberbühler showed that Putty-nosed monkeys sometimes produce distinct pyow-hack sequences made of a small nu... | [
"The Human Mind and Its Complexity",
"Environmental Biology, Ecology and Evolution"
] |
W1990519231 | Preparation and Photocatalytic Properties of Nano Ni/TiO<sub>2</sub> Composite in Alginate | New nano nickel-doped titanium dioxide composites had been produced by a conducting sol-gel method. The alginate gel was used as a template to prevent the conglomeration of the inorganic materials. In this experiment, nickel nitrate, tetrabutyl titanate and sodium alginate were used as main materials to prepare differe... | [
"Physical and Analytical Chemical Sciences",
"Condensed Matter Physics"
] |
10.1371/journal.ppat.1005585 | Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets | Here we describe a chemical biology strategy performed in Staphylococcus aureus and Staphylococcus epidermidis to identify MnaA, a 2-epimerase that we demonstrate interconverts UDP-GlcNAc and UDP-ManNAc to modulate substrate levels of TarO and TarA wall teichoic acid (WTA) biosynthesis enzymes. Genetic inactivation of ... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Immunity, Infection and Immunotherapy",
"Prevention, Diagnosis and Treatment of Human Diseases",
"Physical and Analytical Chemical Sciences"
] |
10.3791/3453 | Electric Field Controlled Directed Migration Of Neural Progenitor Cells In 2D And 3D Environments | Endogenous electric fields (EFs) occur naturally in vivo and play a critical role during tissue/organ development and regeneration, including that of the central nervous system1,2. These endogenous EFs are generated by cellular regulation of ionic transport combined with the electrical resistance of cells and tissues. ... | [
"Neuroscience and Disorders of the Nervous System",
"Cell Biology, Development, Stem Cells and Regeneration"
] |
W2193870916 | Improving neural network performance on SIMD architectures | Neural network calculations for the image recognition problems can be very time consuming. In this paper we propose three methods of increasing neural network performance on SIMD architectures. The usage of SIMD extensions is a way to speed up neural network processing available for a number of modern CPUs. In our expe... | [
"Computer Science and Informatics",
"Systems and Communication Engineering"
] |
10.1109/TIA.2017.2704908 | On Secondary Control Approaches For Voltage Regulation In Dc Microgrids | Centralized or decentralized secondary controller is commonly employed to regulate the voltage drop raised by the primary controller. However, in the case of high capacity microgrids (MGs) and long feeders with much voltage drop on the line resistances, the conventional methods may not guarantee the voltage regulation ... | [
"Systems and Communication Engineering",
"Products and Processes Engineering"
] |
10.1039/C4FD00195H | Unfolding The Contents Of Sub Nm Plasmonic Gaps Using Normalising Plasmon Resonance Spectroscopy | Plasmonic coupling of gold nanoparticles to a gold surface creates intense plasmonic hot spots with large electromagnetic field-enhancements within the cavity formed by the two metallic surfaces. The localised field in such structures is extremely sensitive to morphological fluctuations and subtle changes in the dielec... | [
"Physical and Analytical Chemical Sciences",
"Condensed Matter Physics"
] |
10.1016/j.jenvp.2017.03.001 | Predictors of visual attention to climate change images: An eye-tracking study | Attentional engagement with climate change is an important precondition for intentional climate-friendly behavior. However, not much is known about the determinants of an individuals’ implicit willingness to attend to this global problem. This study investigates two potentially relevant predictors of implicit attention... | [
"The Human Mind and Its Complexity",
"Earth System Science"
] |
W1574263887 | Non-negative Hidden Markov Modeling of Audio with Application to Source Separation | In recent years, there has been a great deal of work in modeling audio using non-negative matrix factorization and its probabilistic counterparts as they yield rich models that are very useful for source separation and automatic music transcription. Given a sound source, these algorithms learn a dictionary of spectral ... | [
"Computer Science and Informatics",
"Systems and Communication Engineering"
] |
10.1039/c5sm01429h | Shear banding in entangled polymers in the micron scale gap: a confocal-rheoscopic study | Recent shear experiments in well-entangled polymer solutions demonstrated that interfacial wall slip is the only source of shear rate loss and there is no evidence of shear banding in the micron scale gap. | [
"Condensed Matter Physics",
"Physical and Analytical Chemical Sciences"
] |
10.1111/j.1365-2486.2012.02701.x | Comprehensive methodological analysis of long-term changes in phenological extremes in Germany | This study reports on alterations in the magnitude and frequency of extremes in reproductive phenology using long-term records (1951-2008) for plant species widely distributed across Germany. For each of fourteen indicator phases studied, time series of annual onset dates at up to 119 stations, providing 50-58 years of... | [
"Earth System Science",
"Environmental Biology, Ecology and Evolution",
"Mathematics"
] |
10.1177/0956797617714828 | Reciprocity Outperforms Conformity To Promote Cooperation | Evolutionary psychologists have proposed two processes that could give rise to the pervasiveness of human cooperation observed among individuals who are not genetically related: reciprocity and conformity. We tested whether reciprocity outperformed conformity in promoting cooperation, especially when these psychologica... | [
"The Human Mind and Its Complexity",
"The Social World and Its Interactions"
] |
EP 2020077986 W | LOG GRAB | The present invention relates to the geometrical shape of a grab, a single grab element (one-element grab) thereof in the form of a solid and/or a hollow profile engaging in a closed grab element. The invention is used predominantly in timber processing. | [
"Products and Processes Engineering",
"Materials Engineering"
] |
10.1039/B810669J | Reversible Electronic Energy Transfer A Means To Govern Excited State Properties Of Supramolecular Systems | A strategy to manage energy, following light absorption, and modulate excited-state properties, including luminescence lifetimes of multicomponent photoactive systems, is presented. The intervening mechanism, which is illustrated through the use of bi-/multi-chromophoric molecules, relies on energy shuttling between di... | [
"Physical and Analytical Chemical Sciences",
"Condensed Matter Physics"
] |
10.1007/s00425-018-2989-4 | LAESI mass spectrometry imaging as a tool to differentiate the root metabolome of native and range-expanding plant species | Main conclusion: LAESI-MSI, an innovative high-throughput technique holds a unique potential for untargeted detection, profiling and spatial localization of metabolites from intact plant samples without need for extraction or extensive sample preparation. Our understanding of chemical diversity in biological samples ha... | [
"Physical and Analytical Chemical Sciences",
"Environmental Biology, Ecology and Evolution",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
W34812821 | Findings with AVC Design for Mitigation of Human Induced Vibrations in Office Floors | In recent years, there have been extensive active vibration control (AVC) studies for the mitigation of human induced vibrations in a series of office floors, in which such vibrations are deemed to be ‘problematic’ and have been found to affect only certain sections of the floors. These floors are predominantly open-pl... | [
"Products and Processes Engineering",
"Systems and Communication Engineering"
] |
10.1038/nchembio.2380 | Engineering protein stability with atomic precision in a monomeric miniprotein | Miniproteins simplify the protein-folding problem, allowing the dissection of forces that stabilize protein structures. Here we describe PPα-Tyr, a designed peptide comprising an α-helix buttressed by a polyproline II helix. PPα-Tyr is water soluble and monomeric, and it unfolds cooperatively with a midpoint unfolding ... | [
"Physical and Analytical Chemical Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.18632/oncotarget.12002 | Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition | EZH2 inhibitors have gained great interest for their use as anti-cancer therapeutics. However, most research has focused on EZH2 mutant cancers and recently adverse effects of EZH2 inactivation have come to light. To determine whether colorectal cancer cells respond to EZH2 inhibition and to explore which factors influ... | [
"Cell Biology, Development, Stem Cells and Regeneration",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Physiology in Health, Disease and Ageing"
] |
10.1145/2661229.2661236 | Dual Strip Weaving Interactive Design Of Quad Layouts Using Elastica Strips | We introduce Dual Strip Weaving, a novel concept for the interactive design of quad layouts, i. e. partitionings of freeform surfaces into quadrilateral patch networks. In contrast to established tools for the design of quad layouts or subdivision base meshes, which are often based on creating individual vertices, edg... | [
"Computer Science and Informatics"
] |
10.1142/S0218301318300035 | Tmd Gluon Distributions At Small X In The Cgc Theory | In this paper, we review recent progress in the description of unpolarized transverse-momentum-dependent (TMD) gluon distributions at small x in the color glass condensate (CGC) effective theory. We discuss the origin of the nonuniversality of TMD gluon distributions in the TMD factorization framework and in the CGC th... | [
"Fundamental Constituents of Matter"
] |
10.1016/j.jbiotec.2014.04.005 | Small RNA cloning and sequencing strategy affects host and viral microRNA expression signatures | The establishment of the microRNA (miRNA) expression signatures is the basic element to investigate the role played by these regulatory molecules in the biology of an organism. Marek's disease virus 1 (MDV-1) is an avian herpesvirus that naturally infects chicken and induces T cells lymphomas. During latency, MDV-1, li... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems",
"Immunity, Infection and Immunotherapy"
] |
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