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EP 22189130 A
LOCK ASSEMBLY, SOLAR PANEL MOUNTING APPARATUS, AND RECREATIONAL VEHICLE
Provided are a lock assembly, a solar panel mounting apparatus, and a recreational vehicle. The lock assembly includes a driving member (1), a locking member (2), and a latch (110). The driving member (1) includes a connection end (11), and a driving end (12) movable with respect to the connection end (11). The connect...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1146/annurev-neuro-070815-013824
Ten Years of Grid Cells
The medial entorhinal cortex (MEC) creates a neural representation of space through a set of functionally dedicated cell types: grid cells, border cells, head direction cells, and speed cells. Grid cells, the most abundant functional cell type in the MEC, have hexagonally arranged firing fields that tile the surface of...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1016/j.biopsycho.2015.10.009
Interoceptive awareness in patients with functional neurological symptoms
Historically, emotional factors, such as trauma or psychological conflict, have been suggested as causal factors of functional motor disorders (FMD). More recent approaches have instead stressed potential neural and cognitive abnormalities in the allocation and maintenance of attention. Yet these studies have mostly fo...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing" ]
interreg_188
Sustainable Sediment Management of Alpine Reservoirs considering ecological and economical aspects
The Alpine Region is regarded as the most valuable source of clean drinking water in Europe and of great importance for hydro power use. Management of water as an extremely valuable resource is guaranteed by numerous reservoirs enabling a third essential task: flood protection. Sediments are transported in rivers origi...
[ "Products and Processes Engineering", "Earth System Science" ]
W1976462028
Speeding up of genetic algorithm for network topology optimization with use of cumulative updating of network reliability
Network optimization problems in conditions of constraints are NP-hard problems mostly. Genetic Algorithms are applicable solution for network structure optimization and for obtaining good results within acceptable periods of time. In this study we consider the problem of network topology optimization with unreliable c...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
interreg_628
Sustainable MED Cities
Energy efficiency improvement is a key strategy to reduce the environmental impact of public buildings. But usually energy efficiency plans do not fully exploit the potential for synergies that groups of buildings might offer. Energy efficient measures and their implementation at neighbourhood level (i.e. district heat...
[ "Products and Processes Engineering", "Human Mobility, Environment, and Space" ]
10.3390/rs9070735
Large-scale, multi-temporal remote sensing of palaeo-river networks: A case study from Northwest India and its implications for the indus civilisation
Remote sensing has considerable potential to contribute to the identification and reconstruction of lost hydrological systems and networks. Remote sensing-based reconstructions of palaeo-river networks have commonly employed single or limited time-span imagery, which limits their capacity to identify features in comple...
[ "The Study of the Human Past", "Earth System Science" ]
10.1039/C6CE00193A
From Benzodithiophene To Diethoxy Benzodithiophene Covalent Organic Frameworks Structural Investigations
The incorporation of side groups into a covalent organic framework (COF) backbone can be of significant importance for developing new frameworks with enhanced properties. Here we present a novel π-stacked thiophene-based COF containing a benzodithiophene building unit modified with ethoxy side chains. The resulting BDT...
[ "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
981175
Microgel-Based high-performance smart filtration membranes for liquid nuclear waste treatment
The release of radioactive isotopes, with caesium (e.g. 137Cs+) being the most abundant species, are polluting a large quantity of water, substantially threatening human health, while the remediation remains challenging. Membrane separation is a good technology for water treatment thanks to its flexibility and easy up-...
[ "Physical and Analytical Chemical Sciences", "Materials Engineering", "Products and Processes Engineering" ]
10.1021/acs.nanolett.9b00268
Coexistence of Elastic Modulations in the Charge Density Wave State of 2 H-NbSe <inf>2</inf>
Bulk and single-layer 2H-NbSe 2 exhibit identical charge density wave order (CDW) with a quasi-commensurate 3 × 3 superlattice periodicity. Here we combine scanning tunnelling microscopy (STM) imaging at T = 1 K of 2H-NbSe 2 with first-principles density functional theory (DFT) calculations to investigate the structura...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
W298899029
Reliability of the VDO Clip-based Goniometry Method for Measuring Range of Motion of the Elbow
Purpose: Telemedicine is an adaptation of internet-based communication for remote patients. The video (VDO) clip-based goniometry method is a type of telemedicine that would be useful for patients who need periodic assessment. A previous report showed the validation of this technique but it did not verify the generaliz...
[ "Products and Processes Engineering", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1167/12.2.10
Visual Motion Distorts Visual And Motor Space
Much evidence suggests that visual motion can cause severe distortions in the perception of spatial position. In this study, we show that visual motion also distorts saccadic eye movements. Landing positions of saccades performed to objects presented in the vicinity of visual motion were biased in the direction of moti...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
W2299086563
Error assessment of satellite-derived lead fraction in the Arctic
Abstract. Leads within consolidated sea ice control heat exchange between the ocean and the atmosphere during winter, thus constituting an important climate parameter. These narrow elongated features occur when sea ice is fracturing under the action of wind and currents, reducing the local mechanical strength of the ic...
[ "Earth System Science", "Systems and Communication Engineering" ]
10.1002/anie.201705932
Anaerobic Origin of Ergothioneine
Ergothioneine is a sulfur metabolite that occurs in microorganisms, fungi, plants, and animals. The physiological function of ergothioneine is not clear. In recent years broad scientific consensus has formed around the idea that cellular ergothioneine primarily protects against reactive oxygen species. Herein we provid...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1137/17M1125388
The Effect On Fisher Kpp Propagation In A Cylinder With Fast Diffusion On The Boundary
In this paper we consider a reaction-diffusion equation of Fisher-KPP type inside an infinite cylindrical domain in $\mathbb{R}^{N+1}$, coupled with a reaction-diffusion equation on the boundary of the domain, where potentially fast diffusion is allowed. We will study the existence of an asymptotic speed of propagation...
[ "Mathematics" ]
US 2007/0081980 W
SYSTEM AND METHOD FOR ESTABLISHING A COMMUNICATIONS SESSION WITH AN END-USER BASED ON THE STATE OF A NETWORK CONNECTION
A method for establishing a communications session includes receiving a request to initiate a communications session. The request is associated with an end-user and the end-user is associated with at least two identifiers. The method also includes selecting one of the at least two identifiers in response to performance...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
W815257151
Molecular modus operandi of ligand-gated ion channels : Studies of trimeric P2X receptors and pentameric GABA A receptors
This thesis, by using various chemical and biological tools, focuses on the molecular modus operandi of two different superfamilies of ligand-gated ion channels: P2XRs and GABAARs. P2XR is a cation-selective ion channel gated by extracellular ATP (and is implicated in diverse physiological processes, from synaptic tran...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W2036399578
Development and characterisation of soluble polymeric particles for pulmonary peptide delivery
Pulmonary administration of protein and peptide drugs using inhaled dry powder particles is an interesting alternative to parenteral delivery. The stabilisation of these molecules is essential to the maintenance of biological activity in such inhalation formulations. Here salmon calcitonin (sCT) was co-spray dried with...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases", "Materials Engineering" ]
10.1038/nature13043
Disclinations provide the missing mechanism for deforming olivine-rich rocks in the mantle
Mantle flow involves large strains of polymineral aggregates. The strongly anisotropic plastic response of each individual grain in the aggregate results from the interactions between neighbouring grains and the continuity of material displacement across the grain boundaries. Orthorhombic olivine, which is the dominant...
[ "Condensed Matter Physics", "Earth System Science" ]
10.1021/acschembio.8b00270
Detection of Chemical Engagement of Solute Carrier Proteins by a Cellular Thermal Shift Assay
Solute carriers (SLCs) are transmembrane proteins that transport various nutrients, metabolites, and drugs across cellular membranes. Despite the relevance of SLCs to cell homeostasis, metabolism, and disease states, for the majority of SLCs we lack experimental evidence regarding the nature of the cognate ligands, whe...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physical and Analytical Chemical Sciences", "Cell Biology, Development, Stem Cells and Regeneration" ]
W1990946951
Determination of melamine concentrations in dairy samples
Abstract Melamine, a basic organic chemical intermediate, can cause renal failure because of the formation of insoluble melamine cyanurate crystals in the kidneys. This study examined a novel fluorescence spectrometry for the determination of trace melamine in dairy. The method was based on the inhibitory effect of mel...
[ "Physical and Analytical Chemical Sciences", "Products and Processes Engineering" ]
Q4574666
Research and development of the new MEDIMONITOR system for intelligent diagnostic forecasting
The subject of the proposed project is to create a software platform with elements of knowledge management and artificial intelligence. Its output will be a new MEDIMONITOR system using artificial intelligence, which will significantly affect treatments, especially where there is a diagnosis with a long-term impact, wi...
[ "Computer Science and Informatics", "Prevention, Diagnosis and Treatment of Human Diseases" ]
GB 2009001857 W
PUMP
A progressive cavity pump is provided, having a stator section and a rotor section axially aligned with and surrounded by the stator section, a drive shaft connection section and a suction chamber, arranged between the stator section and the drive shaft connection section; wherein the suction chamber is configured such...
[ "Products and Processes Engineering" ]
10.1007/978-3-662-48971-0_48
Effectiveness Of Structural Restrictions For Hybrid Csps
Constraint Satisfaction Problem (CSP) is a fundamental algorithmic problem that appears in many areas of Computer Science. It can be equivalently stated as computing a homomorphism \({\mathbf {R}\rightarrow \varvec{\Gamma }}\) between two relational structures, e. g. between two directed graphs. Analyzing its complexi...
[ "Computer Science and Informatics", "Mathematics" ]
10.1038/s41467-018-04865-7
LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration
Cancer cells' ability to migrate through constricting pores in the tissue matrix is limited by nuclear stiffness. MT1-MMP contributes to metastasis by widening matrix pores, facilitating confined migration. Here, we show that modulation of matrix pore size or of lamin A expression known to modulate nuclear stiffness di...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Physiology in Health, Disease and Ageing" ]
10.1002/dvg.20656
Hoxb8-Cre mice: A tool for brain-sparing conditional gene deletion
The spinal cord is the first site of temporal and spatial integration of nociceptive signals in the pain pathway. Neuroplastic changes occurring at this site contribute critically to various chronic pain syndromes. Gene targeting in mice has generated important insights into these processes. However, the analysis of co...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
US 59780284 A
Rotary multiposition valve
The disclosure is directed to a rotary multiposition valve for selectively directing the flow of a fluid through a plurality of paths. The valve comprises an inner member and a hollow housing with a row of ducts on its outer surface. The ducts are in fluid communication with the housing. An engaging section of the inne...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1109/ISBI.2016.7493375
Optimized In Vivo Conductivity Estimation Using Bem
One of the most important factors limiting the accuracy of source localization with EEG is the ignorance of the conductivity of brain, skull and skin. Because these parameters are highly subject dependent, it has been proposed to estimate them in vivo using an electrical impedance tomographic approach. Here the associa...
[ "Systems and Communication Engineering", "Computer Science and Informatics", "Neuroscience and Disorders of the Nervous System" ]
10.1007/jhep12(2019)177
Four-particle scattering amplitudes in QCD at NNLO to higher orders in the dimensional regulator
Abstract We compute all helicity amplitudes for four particle scattering in massless QCD with n f fermion flavours to next-to-next-to-leading order (NNLO) in perturbation theory. In particular, we consider all possible configurations of external quarks and gluons. We evaluate the amplitudes in terms of a Laurent ser...
[ "Fundamental Constituents of Matter", "Mathematics" ]
10.1021/acsnano.5b01636
Fabrication of Self-Cleaning, Reusable Titania Templates for Nanometer and Micrometer Scale Protein Patterning
The photocatalytic self-cleaning characteristics of titania facilitate the fabrication of reuseable templates for protein nanopatterning. Titania nanostructures were fabricated over square centimeter areas by interferometric lithography (IL) and nanoimprint lithography (NIL). With the use of a Lloyd's mirror two-beam i...
[ "Condensed Matter Physics", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Materials Engineering" ]
10.1007/JHEP01(2020)004
Metastable Vacua In Large N Qcd3
We reexamine the vacuum structure of three-dimensional quantum chromodynamics (QCD3) with gauge group SU(N), Nf fundamental quark flavors, and a level-k Chern-Simons term. This analysis can be reliably carried out in the large-N, fixed Nf, k limit of the theory, up to certain assumptions that we spell out explicitly. A...
[ "Fundamental Constituents of Matter", "Mathematics" ]
interreg_1581
Development of ecosystem-based risk governance concepts with respect to natural hazards and climate impacts – from ecosystem-based solutions to integrated risk assessment
In natural hazard and risk reduction worldwide, but especially in the Alpine Space (AS), forests and mountain ecosystems are outstandingly important, and are increasingly considered on-par with technical measures or other prevention concepts. Forests efficiently protect against avalanches, torrents, landslides or rock-...
[ "Earth System Science", "Human Mobility, Environment, and Space", "Institutions, Governance and Legal Systems" ]
10.1021/acs.cgd.8b01134
Tuning the particle sizes in spherical agglomeration
This paper presents an experimental technique for tuning the size of spherical agglomerates together with a simple model that provides qualitative information on the agglomerate size. Spherical agglomerates of benzoic acid of varying sizes using toluene as the bridging liquid were obtained with a very good reproducibil...
[ "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
3727215
Governing resource urbanisation (grout): multi-stakeholder governance of extractive industries in the era of planetary urbanisation
GROUT will address the governance challenges posed by mining projects advancing close to urban areas. Europe is making a concerted effort to increase a sustainable supply of minerals from European sources, This project will improve knowledge and expertise on the governance of these urbanising frontiers. This fellowship...
[ "Human Mobility, Environment, and Space", "Institutions, Governance and Legal Systems", "Environmental Biology, Ecology and Evolution" ]
10.1038/ngeo3009
Fluid-driven metamorphism of the continental crust governed by nanoscale fluid flow
The transport of fluids through the Earth's crust controls the redistribution of elements to form mineral and hydrocarbon deposits, the release and sequestration of greenhouse gases, and facilitates metamorphic reactions that influence lithospheric rheology. In permeable systems with a well-connected porosity, fluid tr...
[ "Condensed Matter Physics", "Earth System Science" ]
10.1073/pnas.1414293111
Intrinsically organized resting state networks in the human spinal cord
Spontaneous fluctuations in functional magnetic resonance imaging (fMRI) signals of the brain have repeatedly been observed when no task or external stimulation is present. These fluctuations likely reflect baseline neuronal activity of the brain and correspond to functionally relevant resting-state networks (RSN). It ...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing" ]
W2019732914
Development of a Standard Checklist for Protection to Electrical Accidents of Laboratory
대학 연구기관 등의 연구실에서 감전, 전기화재 등 전기사고방지를 위해 수행하는 전기분야 정기점검에 대한 문제점을 파악하고 명확한 기준이 없는 점검항목에 대해 실제 효율적으로 적용 가능하도록 구체적인 기준을 제시한다. 그래서 연구실 전기안전취약요인을 개선하도록 체계적이고 능률적인 정기점검 실시를 위한 표준모델을 마련하고자 한다. 또한, 모든 연구실의 전기안전환경을 중심으로 객관적인 평가가 가능하도록 공통으로 적용될 수 있는 점검항목을 도출하여 연구실 전기안전관리에 부합하도록 연구실 정기점검 전기분야 체크리스트를 개발 한다. 본 연구에서 개발된 전기분야 체크리스트는 실제...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
2719547
Software parallelisation with emmtrix parallel studio
The introduction of multicore processors in 2005 enabled a wide range of computation-intensive real-time applications, in the PC and embedded sector. Especially high-performance embedded systems, as used in today’s automotive technologies (like driver assistance systems), in avionics but also in industrial automation, ...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1093/mnras/sty859
KiDS-i-800: Comparing weak gravitational lensing measurements from same-sky surveys
We present a weak gravitational lensing analysis of 815 deg2 of i-band imaging from the Kilo-Degree Survey (KiDS-i-800). In contrast to the deep r-band observations, which take priority during excellent seeing conditions and form the primary KiDS data set (KiDS-r-450), the complementary yet shallower KiDS-i-800 spans a...
[ "Universe Sciences", "Computer Science and Informatics" ]
10.1080/20414005.2017.1329268
Dimensions Of Justice And Justification In Eu And Transnational Contexts
ABSTRACTThe introduction to this special issue presents and explains the main idea behind each contribution to this collection of papers. Specifically, this special issue explores a grammar of justice and justification through political theory, legal and sociological perspectives, and discusses their relevance in EU an...
[ "Institutions, Governance and Legal Systems", "The Social World and Its Interactions" ]
Q4213694
POR LABBIO CRISTINA
PEDIDO DE CONCESSÃO PREVISTA NO ANÚNCIO PÚBLICO DE PEQUENAS SUBVENÇÕES A PME SUSPENSAS OU COM UMA GRAVE DIMINUIÇÃO DO VOLUME DE NEGÓCIOS
[ "Individuals, Markets and Organisations" ]
W1989602875
Full-term development of rats from oocytes fertilized in vitro using cryopreserved ejaculated sperm
For preservation of rat spermatozoa, the general-purpose method requires that the male be sacrificed for collection of spermatozoa from the epididymides. However, it would be highly useful if the ejaculated spermatozoa could be successfully cryopreserved and the frozen-thawed spermatozoa used for in vitro fertilization...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Biotechnology and Biosystems Engineering" ]
10.1021/acs.biochem.8b01150
Tuning Protein Diffusivity with Membrane Tethers
Diffusion is essential for biochemical processes because it dominates molecular movement on small scales. Enzymatic reactions, for example, require fast exchange of substrate and product molecules in the local environment of the enzyme to ensure efficient turnover. On larger spatial scales, diffusion of secreted signal...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
2723733
Support to the vice-presidents of the erc scientific council 2019
The European Research Council (ERC) provides a competitive platform for investigator-driven frontier research at the European level. It is led by a Scientific Council (ScC) consisting of 21 eminent scientists and their President, and it is this council that independently establishes and oversees theERC's scientific man...
[ "Institutions, Governance and Legal Systems" ]
10.1021/ja508213d
Rational design of pH-controlled DNA strand displacement
Achieving strategies to finely regulate with biological inputs the formation and functionality of DNA-based nanoarchitectures and nanomachines is essential toward a full realization of the potential of DNA nanotechnology. Here we demonstrate an unprecedented, rational approach to achieve control, through a simple chang...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
Q98025
Implementazione di un processo tecnologico innovativo al fine di ampliare l'offerta dell'azienda "MAL-PAK".
Questo progetto riguarda l'implementazione di una nuova tecnologia di stampa industriale che utilizza inchiostri ecologici rispettosi dell'acqua. Il richiedente implementerà il nuovo processo e amplierà l'offerta del prodotto. Il livello di innovazione del progetto è stato definito come un'innovazione a livello naziona...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1093/cercor/bht201
High-expanding cortical regions in human development and evolution are related to higher intellectual abilities
Cortical surface area has tremendously expanded during human evolution, and similar patterns of cortical expansion have been observed during childhood development. An intriguing hypothesis is that the high-expanding cortical regions also show the strongest correlations with intellectual function in humans. However, we ...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
W2087149761
Postoperative Orgasmic Function Increases over Time in Patients Undergoing Nerve-Sparing Radical Prostatectomy
Postprostatectomy orgasmic function (OF) remains poorly defined.To assess OF over time in patients who underwent bilateral nerve-sparing radical retropubic prostatectomy (BNSRRP) for organ-confined prostate cancer (PCa).Baseline data were obtained from 334 consecutive preoperatively sexually active PCa patients at hosp...
[ "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
758885
4-Colours/2-Junctions of III-V semiconductors on Si to use in electronics devices and solar cells
It was early predicted by M. Green and coeval colleagues that dividing the solar spectrum into narrow ranges of colours is the most efficient manner to convert solar energy into electrical power. Multijunction solar cells are the current solution to this challenge, which have reached over 30% conversion efficiencies by...
[ "Condensed Matter Physics", "Materials Engineering", "Synthetic Chemistry and Materials" ]
10.1534/genetics.118.301019
Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans
Abstract In vitro studies suggest that stress may generate random standing variation and that different cellular and ploidy states may evolve more rapidly under stress. Yet this idea has not been tested with pathogenic fungi growing within their host niche in vivo. Here, we analyzed the generation of both genotypic and...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1016/j.neuropsychologia.2018.12.008
Is ventromedial prefrontal cortex critical for behavior change without external reinforcement?
Cue-approach training (CAT) is a novel paradigm that has been shown to induce preference changes towards items without external reinforcements. In the task, the mere association of a neutral cue and a speeded button response has been shown to induce a behavioral choice preference change lasting for months. This paradig...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1364/OL.43.000022
Kilohertz Binary Phase Modulator For Pulsed Laser Sources Using A Digital Micromirror Device
The controlled modulation of an optical wavefront is required for aberration correction, digital phase conjugation or patterned photostimulation. For most of these applications it is desirable to control the wavefront modulation at the highest rates possible. The digital micromirror device (DMD) presents a cost-effecti...
[ "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
W2046643148
A systematic review of short courses for nonspecialist education in intensive care
The availability of reliable and accessible educational material for the training of nonspecialist intensive care physicians is potentially advantageous. We assessed the availability, cost, and content of generic short courses designed to teach basic critical care skills to junior physicians or nonspecialist intensive ...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "The Social World and Its Interactions" ]
10.1084/jem.20131274
SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells
Prnp−/− mice lack the prion protein PrPC and are resistant to prion infections, but variable phenotypes have been reported in Prnp−/− mice and the physiological function of PrPC remains poorly understood. Here we examined a cell-autonomous phenotype, inhibition of macrophage phagocytosis of apoptotic cells, previously ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Immunity, Infection and Immunotherapy" ]
10.1126/science.1256917
Closing the cohesin ring: Structure and function of its Smc3-kleisin interface
Through their association with a kleisin subunit (Scc1), cohesin's Smc1 and Smc3 subunits are thought to form tripartite rings that mediate sister chromatid cohesion. Unlike the structure of Smc1/Smc3 and Smc1/Scc1 interfaces, that of Smc3/Scc1 is not known. Disconnection of this interface is thought to release cohesin...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration" ]
W193148205
Improving thermal comfort in apparel
Abstract: Comfort is a key factor to be considered in clothing design. Among all the comfort factors, thermal comfort is the primary one, as an important function of clothing is to provide aids in maintaining the thermal balance of the human body and ensure that the heat loss, skin temperature, air movement and humidit...
[ "Materials Engineering", "Products and Processes Engineering" ]
W2070389405
Men and women exhibit a similar time to task failure for a sustained, submaximal elbow extensor contraction
Sex differences in muscle fatigue-resistance have been observed in a variety of muscles and under several conditions. This study compared the time to task failure (TTF) of a sustained isometric elbow extensor (intensity 15% of maximal strength) contraction in young men (n = 12) and women (n = 11), and examined if their...
[ "Physiology in Health, Disease and Ageing" ]
997208
A synergistic approach toward understanding receptor signaling in the cell at very high resolution
Members of the Epidermal Growth Factors Receptor family (EGFRs) influence cell growth and proliferation, and are pivotal in all phases of tumor progression. We will use this receptor family as an example with which to develop a ground-breaking new technology to study cellular signaling towards atomic resolution, in sit...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Physical and Analytical Chemical Sciences", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1038/nsmb.2937
CtIP tetramer assembly is required for DNA-end resection and repair
Mammalian CtIP protein has major roles in DNA double-strand break (DSB) repair. Although it is well established that CtIP promotes DNA-end resection in preparation for homology-dependent DSB repair, the molecular basis for this function has remained unknown. Here we show by biophysical and X-ray crystallographic analys...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.3389/fmicb.2016.01619
Distinct patterns in human milk microbiota and fatty acid profiles across specific geographic locations
Breast feeding results in long term health benefits in the prevention of communicable and non-communicable diseases at both individual and population levels. Geographical location directly impacts the composition of breast milk including microbiota and lipids. The aim of this study was to investigate the influence of g...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1109/VLSIC.2015.7231302
A Tdd Fdd Saw Less Superheterodyne Receiver With Blocker Resilient Band Pass Filter And Multi Stage Hr In 28Nm Cmos
A SAW-less discrete-time superheterodyne receiver (RX) with multi-stage harmonic rejection in 28nm CMOS, featuring highly linear LNTA, employs a novel blocker-resilient octal charge-sharing band-pass filter to achieve low power consumption. The RX features NF of 2. 1 to 2. 6 dB, and IIP3 of 8 to 14 dBm, while drawing o...
[ "Systems and Communication Engineering", "Materials Engineering" ]
10.15184/aqy.2019.109
The archaeology and ethnoarchaeology of rain-fed cultivation in arid and hyper-arid North Africa
Abstract
[ "The Study of the Human Past", "Environmental Biology, Ecology and Evolution" ]
US 2007/0078020 W
FOOTREST
A footrest comprising a sling having two ends and a strap connected to each end of the sling. A user in a seat rests a foot in the sling where the straps of the sling are attached around an object in front of the seat.
[ "Products and Processes Engineering" ]
10.1038/s41598-017-11039-w
On the consistency of seismically imaged lower mantle slabs
The geoscience community is increasingly utilizing seismic tomography to interpret mantle heterogeneity and its links to past tectonic and geodynamic processes. To assess the robustness and distribution of positive seismic anomalies, inferred as subducted slabs, we create a set of vote maps for the lower mantle with 14...
[ "Earth System Science" ]
10.1016/j.bpj.2014.07.023
Carbohydrate conformation and lipid condensation in monolayers containing glycosphingolipid Gb3: Influence of acyl chain structure
Globotriaosylceramide (Gb3), a glycosphingolipid found in the plasma membrane of animal cells, is the endocytic receptor of the bacterial Shiga toxin. Using x-ray reflectivity (XR) and grazing incidence x-ray diffraction (GIXD), lipid monolayers containing Gb3 were investigated at the air-water interface. XR probed Gb3...
[ "Condensed Matter Physics", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1038/ncomms5815
Topological excitations in a kagome magnet
Chirality - that is, left or right handedness - is present in many scientific areas, and particularly in condensed matter physics. Inversion symmetry breaking relates chirality with skyrmions, which are protected field configurations with particle-like and topological properties. Here we show that a kagome magnet, with...
[ "Condensed Matter Physics", "Synthetic Chemistry and Materials", "Systems and Communication Engineering" ]
10.1007/JHEP09(2016)034
On Triviality Of S Matrix In Conformal Higher Spin Theory
We consider the conformal higher spin (CHS) theory in d = 4 that contains the s = 1 Maxwell vector, s = 2 Weyl graviton and their higher spin s = 3,4,… counterparts with higher-derivative □ s kinetic terms. The interacting action for such theory can be found as the coefficient of the logarithmically divergent part in...
[ "Fundamental Constituents of Matter", "Mathematics" ]
643863
Laboratory experiments, numerical modelling and field observations of basaltic magma fragmentation
For low viscosity magmas such as basalts, rapid and unpredictable transitions between effusive and explosive activity may occur. These transitions dramatically alter the impact of an eruption and pose a real challenge to policymakers tasked with mitigating the risks associated with basaltic eruptions. Mechanisms contro...
[ "Physical and Analytical Chemical Sciences", "Earth System Science" ]
306576
Quantum Interfaces and Open Systems
Researchers have strived to obtain control of a variety of different quantum systems, each characterized by their own distinct advantages: quantum optical systems offer excellent isolation from the environment while solid state systems allow for integrated micro-fabricated devices. At the same time nuclear spins in mol...
[ "Fundamental Constituents of Matter", "Condensed Matter Physics", "Systems and Communication Engineering" ]
10.1016/j.algal.2017.01.015
Enhanced NADPH production in the pentose phosphate pathway accelerates lipid accumulation in the oleaginous diatom Fistulifera solaris
As a consequence of the environmental concerns linked with the exploitation of fossil fuel reserves, biofuel production using microalgae has been widely considered because of their higher productive capacity compared with land plants. However, genetic modifications will likely be required to further improve the lipid p...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Biotechnology and Biosystems Engineering" ]
W1538993818
Movement and the Paradox of Resistance
In his Progressive Dichotomy Paradox, Zeno argued that a runner will never reach a fixed goal along the racetrack. The reason is that the runner must first reach half the distance to the goal, but when there he must then cross half the remaining distance, then half of the new remainder, and so on. If the goal is one me...
[ "Texts and Concepts", "The Social World and Its Interactions" ]
10.1080/17437199.2016.1138871
What Is The Psychological Impact Of Self Weighing A Meta Analysis
Many people self-weigh and many interventions addressing weight-related problems such as obesity promote self-weighing. However, while self-weighing has been associated with weight loss, there is mixed evidence regarding the psychological impact of this behaviour. The present review aimed to quantify the relationship b...
[ "The Human Mind and Its Complexity" ]
10.1029/2010JB007704
Structure Of North American Mantle Constrained By Simultaneous Inversion Of Multiple Frequency Sh Ss And Love Waves
[1] We simultaneously invert for the velocity and attenuation structure of the North American mantle from a mixed data set: SH wave traveltime and amplitude anomalies, SS wave differential traveltime anomalies, and Love wave fundamental mode phase delays. All data are measured for multiple frequency bands, and finite f...
[ "Earth System Science" ]
10.2217/epi.10.8
In junk we trust: repetitive DNA, epigenetics and facioscapulohumeral muscular dystrophy
Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant myopathy with a peculiar etiology. Unlike most genetic disorders, FSHD is not caused by mutations in a protein-coding gene. Instead, it is associated with contraction of the D4Z4 macrosatellite repeat array located at 4q35. Interestingly, D4Z4 delet...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1364/OL.36.002587
Terahertz Imaging Through Self Mixing In A Quantum Cascade Laser
We demonstrate terahertz (THz) frequency imaging using a single quantum cascade laser (QCL) device for both generation and sensing of THz radiation. Detection is achieved by utilizing the effect of self-mixing in the THz QCL, and, specifically, by monitoring perturbations to the voltage across the QCL, induced by light...
[ "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
984598
Mussila ms (mussila music school) - an innovative solution in music education
Learning music has shown to have relevant benefits for the cognitive development of children, leading to better academic results, work opportunities, higher career goals and more civic engagement. However, traditional methods in music education leave this enormous potential untapped; due to the difficulty of dealing wi...
[ "Products and Processes Engineering", "Computer Science and Informatics", "The Social World and Its Interactions" ]
10.1145/3308558.3313693
The Few Get Richer A Surprising Consequence Of Popularity Based Rankings
Ranking algorithms play a crucial role in online platforms ranging from search engines to recommender systems. In this paper, we identify a surprising consequence of popularity-based rankings: the fewer the items reporting a given signal, the higher the share of the overall traffic they collectively attract. This few-g...
[ "Computer Science and Informatics", "The Social World and Its Interactions" ]
10.1016/j.cam.2013.07.048
Software for weighted structured low-rank approximation
A software package is presented that computes locally optimal solutions to low-rank approximation problems with the following features: mosaic Hankel structure constraint on the approximating matrix,weighted 2-norm approximation criterion,fixed elements in the approximating matrix,missing elements in the data matrix, a...
[ "Computer Science and Informatics", "Mathematics" ]
10.1117/12.2208948
Optimizing The Mode Instability Threshold Of High Power Fiber Laser Systems
In this work we present guidelines to increase the transverse mode instability threshold of high power fiber amplifiers and also, for the first time to the best of our knowledge, of fiber oscillators. These guidelines do not involve changes in the composition of the active material (except for its doping concentration)...
[ "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
W4281785800
Terapia Ocupacional en educación inclusiva
El artículo presenta un panorama de los trabajos de inclusión realizados en Cali y busca agradecer a muchas terapeutas ocupacionales por la trocha que abrieron en este sector en la ciudad. Inicia con un recorrido histórico por las prácticas de terapeutas ocupacionales en educación en Cali, desde la década de 1970, y en...
[ "The Social World and Its Interactions" ]
10.1088/1751-8113/43/22/225303
Classical Statistical Mechanics Approach To Multipartite Entanglement
We characterize the multipartite entanglement of a system of n qubits in terms of the distribution function of the bipartite purity over balanced bipartitions. We search for maximally multipartite entangled states, whose average purity is minimal, and recast this optimization problem into a problem of statistical mecha...
[ "Mathematics", "Fundamental Constituents of Matter", "Condensed Matter Physics" ]
758494
Refiguring Conservation in/for 'the Anthropocene': The Global Lives of the Orangutan
In recent years, conservationists have engaged in heated debates about whether and how conservation should respond to the challenges posed by ‘the Anthropocene’—a term increasingly used to encapsulate the overwhelming, transformative impact of human activity on the Earth system. How are these debates—and the wider ‘Ant...
[ "Environmental Biology, Ecology and Evolution", "The Social World and Its Interactions", "Human Mobility, Environment, and Space" ]
221189
Discovering new catalysts in the cluster-nanoparticle transition regime
The purpose of this proposal is to establish new fundamental insight of the reactivity and thereby the catalytic activity of oxides, nitrides, phosphides and sulfides (O-, N-, P-, S- ides) in the Cluster-Nanoparticle transition regime. We will use this insight to develop new catalysts through an interactive loop involv...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Materials Engineering" ]
W2183659053
Improving Adherence to Screening Colonoscopy Preparation and Appointments
Colorectal screening for cancer by colonoscopy is recommended for adults 50 years and older. Scheduling patients for sedated endoscopic procedures involves balancing physician schedules, room availability and equipment, proper patient preparedness, and necessary personnel. Both nonattendance and poor preparations contr...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Individuals, Markets and Organisations" ]
10.1093/aje/kwv015
Social Participation and Depression in Old Age: A Fixed-Effects Analysis in 10 European Countries
We examined whether changes in different forms of social participation were associated with changes in depressive symptoms in older Europeans. We used lagged individual fixed-effects models based on data from 9,068 persons aged ≥50 years in wave 1 (2004/2005), wave 2 (2006/2007), and wave 4 (2010/2011) of the Survey of...
[ "The Social World and Its Interactions", "The Human Mind and Its Complexity" ]
10.1007/978-3-642-32147-4_16
Minimum Ratio Cover Of Matrix Columns By Extreme Rays Of Its Induced Cone
Given a matrix S∈ℝm ×n and a subset of columns R, we study the problem of finding a cover of R with extreme rays of the cone $\mathcal{F}=\{v \in \mathbb{R}^n \mid Sv=\mathbf{0}, v\geq \mathbf{0}\}$, where an extreme ray v covers a column k if vk>0. In order to measure how proportional a cover is, we introduce two diff...
[ "Mathematics", "Computer Science and Informatics" ]
10.1021/acs.langmuir.8b02631
Effects of Ca<sup>2+</sup> Ion Condensation on the Molecular Structure of Polystyrene Sulfonate at Air-Water Interfaces
The structure of poly(sodium 4-styrenesulfonate) (NaPSS) polyelectrolytes at air-water interfaces was investigated with tensiometry, ellipsometry, and vibrational sum-frequency generation (SFG) in the presence of low and high CaCl2 concentrations. In addition, we have studied the foaming behavior of 20 mM NaPSS solutio...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
283605
THE ORIGIN AND IMPACT OF COLOUR CATEGORIES IN THOUGHT AND LANGUAGE
This proposal outlines a cutting-edge five year project which will push the frontiers of colour category research, and will resonate throughout the cognitive and social sciences. Humans can discriminate millions of colours (Zeki, 1993), yet language refers to colour using a number of discrete categories (e.g., red, gr...
[ "The Human Mind and Its Complexity", "Neuroscience and Disorders of the Nervous System" ]
10.1051/0004-6361/201833292
A Tale Of Two Periods Determination Of The Orbital Ephemeris Of The Super Eddington Pulsar Ngc 7793 P13
We present a timing analysis of multiple XMM-Newton and NuSTAR observations of the ultra-luminous pulsar NGC 7793 P13 spread over its 65d variability period. We use the measured pulse periods to determine the orbital ephemeris, confirm a long orbital period with P_orb = 63. 9 (+0. 5,-0. 6) d, and find an eccentricity o...
[ "Universe Sciences" ]
10.1161/circresaha.119.315730
The Noonan Syndrome Gene Lztr1 Controls Cardiovascular Function by Regulating Vesicular Trafficking
Rationale: Noonan syndrome (NS) is one of the most frequent genetic disorders. Bleeding problems are among the most common, yet poorly defined complications associated with NS. A lack of consensus on the management of bleeding complications in patients with NS indicates an urgent need for new therapeutic approaches. Ob...
[ "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1016/j.cell.2017.03.002
A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family
Natural killer (NK) cells play a key role in innate immunity by detecting alterations in self and non-self ligands via paired NK cell receptors (NKRs). Despite identification of numerous NKR-ligand interactions, physiological ligands for the prototypical NK1. 1 orphan receptor remain elusive. Here, we identify a viral ...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W2900385822
Adoption Constraints for Small-scale Agroforestry-based Biofuel Systems in India
Abstract Small-scale agroforestry-based biofuel production has recently been proposed as a strategy for rural poverty alleviation, but few empirical evidence is available on farmer adoption of such novel systems. This study describes adoption of oilseed tree mixtures on smallholdings in Hassan district, South India, an...
[ "Environmental Biology, Ecology and Evolution", "Biotechnology and Biosystems Engineering", "Individuals, Markets and Organisations" ]
217521
Firm-To-Firm trade networks
This project analyzes the propagation of shocks through international trade. The microeconomic structure of trade networks is argued to favor the propagation and amplification of shocks with an end-effect on the dynamics and volatility of aggregate trade. The exploitation of highly disaggregated firm-to-firm trade data...
[ "Individuals, Markets and Organisations" ]
W903422662
Pressurization method for controllable impulsion of liquids in microfluidic platforms
In this paper, a pressurization method for manufacturing an independent impulsion system is proposed. The method consists in inserting a deformable material filling a microchamber, leading to its pressurization, which will be on charge of the movement of fluid. The reached pressure involves a wide range of positive val...
[ "Products and Processes Engineering", "Materials Engineering", "Systems and Communication Engineering" ]
260678
Molecular studies of synaptic vesicle recycling in health and disease
Synaptic transmission is of paramount importance for neuronal circuit integrity; if synapses fail, circuits fail. Transmission of electrical pulses in our brain is critical for normal but also higher brain functions such as learning, memory formation and thought, and understanding the regulatory processes of synaptic t...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1007/s00125-019-4888-z
Novel therapeutic potential of angiotensin receptor 1 blockade in a rat model of diabetes-associated depression parallels altered BDNF signalling
Aims/hypothesis: Diabetes is a worldwide epidemic linked with diverse diseases of the nervous system, including depression. A few studies suggested a connection between renin–angiotensin–aldosterone system blockers and reduced depressive symptoms, although underlying mechanisms are unclear. Here we investigated the ant...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1007/s11121-018-0941-2
What Affects Attendance and Engagement in a Parenting Program in South Africa?
Parenting programs are a promising approach to improving family well-being. For families to benefit, programs need to be able to engage families actively in the interventions. Studies in high-income countries show varying results regarding whether more disadvantaged families are equally engaged in parenting interventio...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "The Social World and Its Interactions" ]
interreg_3514
Promoting Silver tourism through valorization of MED-diet and wellbeing routes in the CBC area
Silver Wellbeing project aims to create and promote a touristic offer mainly addressed to “silver” public (over 65), that brings together territorial valorization and promotion with the Mediterranean diet and a correct and healthy lifestyle. By adopting the Mediterranean diet and lifestyle (an Intangible Cultural Heri...
[ "Human Mobility, Environment, and Space", "Studies of Cultures and Arts", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1163/23519924-00601002
The Special Issue ‘Forced Migration and Refugeedom in the Modern Middle East’ Towards Connected Histories of Refugeedom in the Middle East
This special issue approaches the study of refugees and forcibly displaced persons in the Middle East beyond the analytic bounds dictated by states, nations and regions. Each author is interested in showing connections, influences, and far-reaching consequences that cut across analytic boundaries. By challenging state-...
[ "The Study of the Human Past", "Human Mobility, Environment, and Space" ]
10.1007/s10963-013-9067-4
East Africa and Madagascar in the Indian Ocean world
The Indian Ocean has long been a forum for contact, trade and the transfer of goods, technologies and ideas between geographically distant groups of people. Another, less studied, outcome of expanding maritime connectivity in the region is the translocation of a range of species of plants and animals, both domestic and...
[ "The Study of the Human Past", "Environmental Biology, Ecology and Evolution" ]