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NCT02880215
28:50:chronic_disease
meets criteria for current substance use disorder (mild or greater severity)
3
[ "meets", "criteria", "for", "current", "substance", "use", "disorder", "(", "mild", "or", "greater", "severity", ")" ]
[ 0, 0, 0, 0, 2, 2, 2, 0, 0, 0, 0, 0, 0 ]
NCT02404155
1:29:chronic_disease
Systemic Lupus Erythematosus
3
[ "Systemic", "Lupus", "Erythematosus" ]
[ 2, 2, 2 ]
NCT02577406
29:51:treatment,59:75:treatment,93:97:chronic_disease
The use of a stable dose of oral steroid post-HSCT and/or topical steroids for ongoing skin GVHD
3
[ "The", "use", "of", "a", "stable", "dose", "of", "oral", "steroid", "post-HSCT", "and/or", "topical", "steroids", "for", "ongoing", "skin", "GVHD" ]
[ 0, 0, 0, 0, 0, 0, 0, 1, 1, 1, 0, 1, 1, 0, 0, 0, 2 ]
NCT02525692
,,24:30:treatment,73:84:treatment,209:218:treatment
Pregnant women because ONC201 is novel agent with unknown potential for teratogenic or abortifacient effects. Because there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with ONC201, breastfeeding should be discontinued if the mother is treated with ONC201
3
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NCT02681211
23:46:treatment,58:67:treatment,77:83:treatment
Patients who received ED migraine medications (including ibuprofen or other NSAIDS) prior to study evaluation
3
[ "Patients", "who", "received", "ED", "migraine", "medications", "(", "including", "ibuprofen", "or", "other", "NSAIDS", ")", "prior", "to", "study", "evaluation" ]
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NCT00871260
1:32:chronic_disease
Second or third degree AV block
3
[ "Second", "or", "third", "degree", "AV", "block" ]
[ 2, 2, 2, 2, 2, 2 ]
NCT03124355
6:42:chronic_disease,,,,159:182:chronic_disease,,263:286:chronic_disease
with Postural Tachycardia Syndrome (POTS) as defined by a heart rate increase ≥30 bpm from supine within 10 min of standing or head-up tilt in the absence of orthostatic hypotension, with chronic symptoms (> 6 months), and in the absence of other acute cause of orthostatic tachycardia
3
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NCT02541903
1:25:cancer
Meningeal carcinomatosis
3
[ "Meningeal", "carcinomatosis" ]
[ 3, 3 ]
NCT02252432
35:44:treatment,57:78:treatment,85:97:treatment,99:109:treatment,111:121:treatment,123:135:treatment,137:153:treatment
Drugs/substances known to inhibit methadone metabolism: macrolide antibiotics e.g., erythromycin, cimetidine, astemizole, voriconazole, grapefruit juice
3
[ "Drugs/substances", "known", "to", "inhibit", "methadone", "metabolism", ":", "macrolide", "antibiotics", "e.g.", ",", "erythromycin", ",", "cimetidine", ",", "astemizole", ",", "voriconazole", ",", "grapefruit", "juice" ]
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NCT02397083
42:52:allergy_name,62:71:allergy_name,86:95:allergy_name,97:109:allergy_name
Known intolerance or hypersensitivity to everolimus or other rapamycin analogs (e.g. sirolimus, temsirolimus)
3
[ "Known", "intolerance", "or", "hypersensitivity", "to", "everolimus", "or", "other", "rapamycin", "analogs", "(", "e.g", ".", "sirolimus", ",", "temsirolimus", ")" ]
[ 0, 0, 0, 0, 0, 4, 0, 0, 4, 0, 0, 0, 0, 4, 0, 4, 0 ]
NCT02631850
93:106:chronic_disease,,128:136:chronic_disease,151:182:chronic_disease
Have medical conditions that would place volunteers at higher risk of adverse events (e.g., renal disease, frailty, pregnancy, dementia, severe pain, end-stage/degenerative diseases)
3
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NCT01676259
4:18:cancer
nonadenocarcinoma histology
3
[ "nonadenocarcinoma", "histology" ]
[ 3, 3 ]
NCT00673842
1:22:chronic_disease,24:36:treatment,40:59:treatment
Chronic renal failure (hemodialysis or peritoneal dialysis)
3
[ "Chronic", "renal", "failure", "(", "hemodialysis", "or", "peritoneal", "dialysis", ")" ]
[ 2, 2, 2, 0, 1, 0, 1, 1, 0 ]
NCT02520427
,,,98:108:treatment
Women planning to become pregnant while on study through 1 week after receiving the last dose of study drug
3
[ "Women", "planning", "to", "become", "pregnant", "while", "on", "study", "through", "1", "week", "after", "receiving", "the", "last", "dose", "of", "study", "drug" ]
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NCT02132598
34:52:cancer,66:82:cancer,105:114:treatment
Previously treated patients with non-squamous NSCLC who have had brain metastases at any point in their treatment history
3
[ "Previously", "treated", "patients", "with", "non-squamous", "NSCLC", "who", "have", "had", "brain", "metastases", "at", "any", "point", "in", "their", "treatment", "history" ]
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NCT02440815
1:15:treatment,23:36:treatment,,64:89:treatment,
Antidepressant use or psychotherapy within the past 6 weeks or electroconvulsive therapy within the past 6 months
3
[ "Antidepressant", "use", "or", "psychotherapy", "within", "the", "past", "6", "weeks", "or", "electroconvulsive", "therapy", "within", "the", "past", "6", "months" ]
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NCT01810588
1:29:chronic_disease
Chronic lymphocytic leukemia, relapsed or with poor prognostic features
3
[ "Chronic", "lymphocytic", "leukemia", ",", "relapsed", "or", "with", "poor", "prognostic", "features" ]
[ 2, 2, 2, 0, 0, 0, 0, 0, 0, 0 ]
NCT02106052
1:3:chronic_disease,
MS diagnosis at least 6 months prior
3
[ "MS", "diagnosis", "at", "least", "6", "months", "prior" ]
[ 2, 0, 0, 0, 0, 0, 0 ]
NCT01925573
22:42:allergy_name
Known sensitivity to conductive hydrogels
3
[ "Known", "sensitivity", "to", "conductive", "hydrogels" ]
[ 0, 0, 0, 4, 4 ]
NCT02158858
,,82:94:treatment,
Platelet count ≥ 75 x 10^9/L without the assistance of thrombopoietic factors or transfusions for at least 14 days
3
[ "Platelet", "count", "≥", "75", "x", "10^9/L", "without", "the", "assistance", "of", "thrombopoietic", "factors", "or", "transfusions", "for", "at", "least", "14", "days" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0 ]
NCT02234934
1:11:chronic_disease
Infectious
3
[ "Infectious" ]
[ 2 ]
NCT03043807
1:17:treatment,24:34:treatment,36:45:treatment,47:58:treatment,60:69:treatment
Hormonal therapy (e.g. leuprolide, goserelin, triptorelin, degarelix)
3
[ "Hormonal", "therapy", "(", "e.g", ".", "leuprolide", ",", "goserelin", ",", "triptorelin", ",", "degarelix", ")" ]
[ 1, 1, 0, 0, 0, 1, 0, 1, 0, 1, 0, 1, 0 ]
NCT02667392
,,22:39:chronic_disease
> 6 months < 5 years post-stroke onset
3
[ ">", "6", "months", "<", "5", "years", "post-stroke", "onset" ]
[ 0, 0, 0, 0, 0, 0, 2, 2 ]
NCT03017196
53:71:chronic_disease
Health professionals who do not treat patients with chronic conditions
3
[ "Health", "professionals", "who", "do", "not", "treat", "patients", "with", "chronic", "conditions" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 2, 2 ]
NCT02203513
,,200:220:treatment
all subjects of reproductive potential must agree to use adequate contraception prior to study entry, for the duration of study participation, and for at least four months following the last dose of experimental therapy
3
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NCT02925923
12:27:treatment,29:40:treatment,42:51:treatment,
use of any thienopyridines (Clopidogrel, Prasugrel) 7 days prior to randomization
3
[ "use", "of", "any", "thienopyridines", "(", "Clopidogrel", ",", "Prasugrel", ")", "7", "days", "prior", "to", "randomization" ]
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NCT02193191
1:14:treatment,
Major surgery in the past 30 days
3
[ "Major", "surgery", "in", "the", "past", "30", "days" ]
[ 1, 1, 0, 0, 0, 0, 0 ]
NCT02327403
13:37:treatment,39:51:treatment,55:65:treatment
Maintenance immunosuppression of CNI (cyclosporine or tacrolimus)
3
[ "Maintenance", "immunosuppression", "of", "CNI", "(", "cyclosporine", "or", "tacrolimus", ")" ]
[ 0, 1, 1, 1, 0, 1, 0, 1, 0 ]
NCT01954576
71:83:treatment,286:294:treatment,296:313:treatment,319:333:treatment,404:419:treatment,455:460:cancer
There must be an interval of at least 12 weeks from the completion of radiotherapy to start of device treatment. When the interval is less than 12 weeks from the completion of radiotherapy, the histological confirmation of progression must be unequivocal per RANO criteria. The use of PET scan, perfusion imaging, and MRspectroscopy to differentiate between true early progression and pseudoprogression prior to biopsy or resection of probable recurrent tumor is per standard of care
3
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NCT02725177
14:22:chronic_disease,24:36:chronic_disease,88:103:treatment
Uncontrolled diabetes, hypertension, or other contra-indication to increased dosage of glucocorticoids
3
[ "Uncontrolled", "diabetes", ",", "hypertension", ",", "or", "other", "contra-indication", "to", "increased", "dosage", "of", "glucocorticoids" ]
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NCT02706249
1:25:chronic_disease
Congestive heart failure (NYHA class III or IV)
3
[ "Congestive", "heart", "failure", "(", "NYHA", "class", "III", "or", "IV", ")" ]
[ 2, 2, 2, 0, 0, 0, 0, 0, 0, 0 ]
NCT03154476
1:33:chronic_disease
Pulmonary veno-occlusive disease
3
[ "Pulmonary", "veno-occlusive", "disease" ]
[ 2, 2, 2 ]
NCT01726257
1:19:chronic_disease
Aneurysmal disease of the descending thoracic aorta
3
[ "Aneurysmal", "disease", "of", "the", "descending", "thoracic", "aorta" ]
[ 2, 2, 0, 0, 0, 0, 0 ]
NCT01625923
44:75:chronic_disease,,124:140:treatment,142:163:treatment,165:177:treatment,180:194:treatment
Use of medications potentially influencing upper gastrointestinal motility or appetite within one week of the study (e.g., prokinetic drugs, macrolide antibiotics (erythromycin), GLP-1 mimetics)
3
[ "Use", "of", "medications", "potentially", "influencing", "upper", "gastrointestinal", "motility", "or", "appetite", "within", "one", "week", "of", "the", "study", "(", "e.g.", ",", "prokinetic", "drugs", ",", "macrolide", "antibiotics", "(", "erythromycin", ")", ",", "GLP-1", "mimetics", ")" ]
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NCT03099070
1:26:chronic_disease
Axis-I psychotic disorder
3
[ "Axis-I", "psychotic", "disorder" ]
[ 2, 2, 2 ]
NCT02770326
8:15:chronic_disease
Active fistula
3
[ "Active", "fistula" ]
[ 0, 2 ]
NCT02588326
22:31:chronic_disease
History of recurrent epistaxis, or any epistaxis requiring medical intervention
3
[ "History", "of", "recurrent", "epistaxis", ",", "or", "any", "epistaxis", "requiring", "medical", "intervention" ]
[ 0, 0, 0, 2, 0, 0, 0, 0, 0, 0, 0 ]
NCT02355912
1:21:treatment
pace maker placement
3
[ "pace", "maker", "placement" ]
[ 1, 1, 1 ]
NCT02311621
141:163:treatment
Presence of any concurrent medical condition that, in the opinion of the protocol PI or designee, would prevent the patient from undergoing protocol-based therapy
3
[ "Presence", "of", "any", "concurrent", "medical", "condition", "that", ",", "in", "the", "opinion", "of", "the", "protocol", "PI", "or", "designee", ",", "would", "prevent", "the", "patient", "from", "undergoing", "protocol-based", "therapy" ]
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NCT02547818
14:23:allergy_name,25:31:allergy_name,33:40:allergy_name,42:49:allergy_name,60:67:allergy_name
Allergies to ibuprofen (Advil®, Motrin®, Nuprin®, etc.) or aspirin
3
[ "Allergies", "to", "ibuprofen", "(", "Advil®", ",", "Motrin®", ",", "Nuprin®", ",", "etc", ".", ")", "or", "aspirin" ]
[ 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4 ]
NCT03113136
25:47:chronic_disease
unstable or significant psychiatric conditions (past and stable conditions will be allowed)
3
[ "unstable", "or", "significant", "psychiatric", "conditions", "(", "past", "and", "stable", "conditions", "will", "be", "allowed", ")" ]
[ 0, 0, 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02210650
31:73:treatment,94:105:treatment,109:111:treatment
Patients scheduled to undergo ureteroscopic removal of ureteral stone(s) that are visible on KUB (x-ray) or CT (i.e., calcium stones)
3
[ "Patients", "scheduled", "to", "undergo", "ureteroscopic", "removal", "of", "ureteral", "stone", "(", "s", ")", "that", "are", "visible", "on", "KUB", "(", "x-ray", ")", "or", "CT", "(", "i.e.", ",", "calcium", "stones", ")" ]
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NCT02770326
1:27:chronic_disease
Inflammatory bowel disease
3
[ "Inflammatory", "bowel", "disease" ]
[ 2, 2, 2 ]
NCT02088554
,20:33:chronic_disease
Child-Pugh Class C liver disease
3
[ "Child-Pugh", "Class", "C", "liver", "disease" ]
[ 0, 0, 0, 2, 2 ]
NCT02286687
,,59:61:treatment,,104:125:treatment,137:176:treatment,172:175:treatment,224:238:treatment,
International normalized ratio (INR) or prothrombin time (PT) =< 1.5 x ULN unless subject is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants; activated PTT (aPTT) =< 1.5 x ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants
3
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NCT02762006
12:39:treatment,,,107:117:treatment,121:133:treatment
Receipt of live attenuated vaccination within 30 days prior to study entry or within 30 days of receiving durvalumab or tremelimumab
3
[ "Receipt", "of", "live", "attenuated", "vaccination", "within", "30", "days", "prior", "to", "study", "entry", "or", "within", "30", "days", "of", "receiving", "durvalumab", "or", "tremelimumab" ]
[ 0, 0, 1, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1 ]
NCT03100539
1:18:chronic_disease,
Chronic neck pain for 6 months or longer
3
[ "Chronic", "neck", "pain", "for", "6", "months", "or", "longer" ]
[ 2, 2, 2, 0, 0, 0, 0, 0 ]
NCT03148795
13:18:chronic_disease,20:27:chronic_disease,32:61:chronic_disease
Significant renal, hepatic, or bone marrow organ dysfunction
3
[ "Significant", "renal", ",", "hepatic", ",", "or", "bone", "marrow", "organ", "dysfunction" ]
[ 0, 2, 0, 2, 0, 0, 2, 2, 2, 2 ]
NCT02338232
39:51:chronic_disease,52:62:treatment,,123:134:treatment
Patient unable to discontinue current hypertension medication for medical or other reasons for two days prior to starting telmisartan
3
[ "Patient", "unable", "to", "discontinue", "current", "hypertension", "medication", "for", "medical", "or", "other", "reasons", "for", "two", "days", "prior", "to", "starting", "telmisartan" ]
[ 0, 0, 0, 0, 0, 2, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
NCT01812174
15:30:chronic_disease
Patients with aortic aneurysm or other medical condition that creates a higher than usual risk of surgical complication
3
[ "Patients", "with", "aortic", "aneurysm", "or", "other", "medical", "condition", "that", "creates", "a", "higher", "than", "usual", "risk", "of", "surgical", "complication" ]
[ 0, 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02719847
39:64:treatment,66:78:treatment,80:98:treatment,100:115:treatment,120:127:treatment
Patients already scheduled to receive conventional radiotherapy, chemotherapy, biological therapy, vaccine therapy, or surgery as treatment
3
[ "Patients", "already", "scheduled", "to", "receive", "conventional", "radiotherapy", ",", "chemotherapy", ",", "biological", "therapy", ",", "vaccine", "therapy", ",", "or", "surgery", "as", "treatment" ]
[ 0, 0, 0, 0, 0, 1, 1, 0, 1, 0, 1, 1, 0, 1, 1, 0, 0, 1, 0, 0 ]
NCT02864277
33:55:cancer,67:74:cancer,76:87:cancer,93:109:cancer
Known or suspected diagnosis of gynecologic malignancy (including ovarian, endometrial, and cervical cancers)
3
[ "Known", "or", "suspected", "diagnosis", "of", "gynecologic", "malignancy", "(", "including", "ovarian", ",", "endometrial", ",", "and", "cervical", "cancers", ")" ]
[ 0, 0, 0, 0, 0, 3, 3, 0, 0, 3, 0, 3, 0, 0, 3, 3, 0 ]
NCT01604512
25:28:treatment,36:45:treatment,47:60:treatment,62:77:treatment
Any contraindication to MRI (e.g., pacemaker, aneurysm clip, tissue expander)
3
[ "Any", "contraindication", "to", "MRI", "(", "e.g.", ",", "pacemaker", ",", "aneurysm", "clip", ",", "tissue", "expander", ")" ]
[ 0, 0, 0, 1, 0, 0, 0, 1, 0, 1, 1, 0, 1, 1, 0 ]
NCT02177695
12:35:chronic_disease
Documented muscle invasive disease
3
[ "Documented", "muscle", "invasive", "disease" ]
[ 0, 2, 2, 2 ]
NCT02532231
,,151:174:treatment
Males who have partners of childbearing potential must agree to use an effective contraceptive method during the study and for 31 weeks following the last dose of study drug
3
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NCT02108860
14:33:chronic_disease,
A history of active tuberculosis within the past 3 years even if treated
3
[ "A", "history", "of", "active", "tuberculosis", "within", "the", "past", "3", "years", "even", "if", "treated" ]
[ 0, 0, 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT01822522
,,,192:202:treatment
all participants of reproductive potential must agree to use both a barrier method and a second method of birth control during the course of the study and for 6 months after the last dose of study drug
3
[ "all", "participants", "of", "reproductive", "potential", "must", "agree", "to", "use", "both", "a", "barrier", "method", "and", "a", "second", "method", "of", "birth", "control", "during", "the", "course", "of", "the", "study", "and", "for", "6", "months", "after", "the", "last", "dose", "of", "study", "drug" ]
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NCT02510417
10:13:treatment,15:22:treatment,32:78:treatment,
Received ATG, Campath or other T cell immunosuppressive monoclonal antibodies in the last 28 days
3
[ "Received", "ATG", ",", "Campath", "or", "other", "T", "cell", "immunosuppressive", "monoclonal", "antibodies", "in", "the", "last", "28", "days" ]
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NCT03109210
1:26:chronic_disease
imminent risk for suicide
3
[ "imminent", "risk", "for", "suicide" ]
[ 2, 2, 2, 2 ]
NCT02335671
37:92:treatment,118:123:cancer,161:164:treatment,193:219:treatment
Participants must be candidates for definitive local therapy with breast conserving therapy (this takes into account tumor to breast size ratio appropriate for BCS, and the ability to undergo standard radiation therapy post-operatively)
3
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NCT00338065
15:34:chronic_disease
Patients with open-angle glaucoma
3
[ "Patients", "with", "open-angle", "glaucoma" ]
[ 0, 0, 2, 2 ]
NCT02525692
103:109:cancer,187:196:treatment,199:211:treatment,239:267:treatment,312:330:treatment,321:330:treatment,336:353:cancer,435:444:treatment,455:462:treatment,520:537:cancer,604:619:treatment,748:760:cancer,781:807:treatment,929:951:cancer,969:984:cancer
For Arm A or D: Any number of recurrences are allowable. For Arm B: First recurrence (only) WHO Grade glioma. First recurrence is defined as progression following initial therapy (i.e., radiation ± chemotherapy). For participants who had prior therapy with radiation or chemotherapy for a low-grade glioma, the surgical diagnosis of a high-grade glioma will be considered the first recurrence. For patients who did not get additional treatment following surgery and diagnosis of low-grade glioma, surgical diagnosis of high grade glioma will not be considered the first recurrence. Instead, progression after treatment will be considered first recurrence. For Arm C: Patients must have clinical and/or radiographic evidence of first recurrence of glioblastoma and be eligible for salvage surgical resection as deemed by the site Investigator. For Arm E: Patients must have clinical and/or radiographic evidence of recurrence of diffuse midline glioma defined as a WHO Grade IV glioma involving the pons, thalamus or spinal cord, and be eligible for salvage surgical resection as deemed by the site Investigator
3
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NCT02588326
17:37:treatment,
Exposure to any investigational drug within 30 days of enrollment
3
[ "Exposure", "to", "any", "investigational", "drug", "within", "30", "days", "of", "enrollment" ]
[ 0, 0, 0, 1, 1, 0, 0, 0, 0, 0 ]
NCT02579161
23:34:treatment
Patients currently on antibiotics immediately prior to the procedure
3
[ "Patients", "currently", "on", "antibiotics", "immediately", "prior", "to", "the", "procedure" ]
[ 0, 0, 0, 1, 0, 0, 0, 0, 0 ]
NCT02025465
16:45:chronic_disease,41:44:chronic_disease,95:116:chronic_disease,118:134:chronic_disease,158:173:chronic_disease,176:189:treatment,196:215:treatment
A diagnosis of acute coronary syndrome (ACS) made by the admitting ED physician (ST elevation myocardial infarction, non-ST elevation myocardial infarction, unstable angina) (beta blockers are a Class I medications for ACS)
3
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NCT02373644
1:17:chronic_disease
Spinal fractures
3
[ "Spinal", "fractures" ]
[ 2, 2 ]
NCT02412540
26:39:chronic_disease
No evidence of any other liver disease by history, screening tests or histological evaluation
3
[ "No", "evidence", "of", "any", "other", "liver", "disease", "by", "history", ",", "screening", "tests", "or", "histological", "evaluation" ]
[ 0, 0, 0, 0, 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02128100
1:20:treatment,
Whole body PET scan within 8 weeks of registration
3
[ "Whole", "body", "PET", "scan", "within", "8", "weeks", "of", "registration" ]
[ 1, 1, 1, 1, 0, 0, 0, 0, 0 ]
NCT02525029
42:61:treatment,63:71:treatment,73:85:treatment,94:106:treatment
Unwilling or unable to stop supplemental sex hormone therapy (estrogen, progesterone, and/or testosterone preparations)
3
[ "Unwilling", "or", "unable", "to", "stop", "supplemental", "sex", "hormone", "therapy", "(", "estrogen", ",", "progesterone", ",", "and/or", "testosterone", "preparations", ")" ]
[ 0, 0, 0, 0, 0, 0, 1, 1, 1, 0, 1, 0, 1, 0, 0, 1, 0, 0 ]
NCT02394704
20:38:treatment,77:91:treatment,93:108:treatment,110:120:treatment,126:149:treatment,,212:222:treatment
Current use of any psychotropic drugs thought to affect learning, including antipsychotics, anticonvulsants, stimulants, and anti-Parkinsonian drugs. Current is defined as within 2 weeks of testing, 4 weeks for fluoxetine
3
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NCT03082612
45:68:treatment
Have completed more than half of prescribed chemotherapy treatments
3
[ "Have", "completed", "more", "than", "half", "of", "prescribed", "chemotherapy", "treatments" ]
[ 0, 0, 0, 0, 0, 0, 0, 1, 1 ]
NCT01419561
1:13:chronic_disease,,
Hyponatremia (sodium<135mmol/L)
3
[ "Hyponatremia", "(", "sodium", "<", "135mmol/L", ")" ]
[ 2, 0, 0, 0, 0, 0 ]
NCT02956486
1:20:cancer,
Malignant neoplasms within 5 years of Screening
3
[ "Malignant", "neoplasms", "within", "5", "years", "of", "Screening" ]
[ 3, 3, 0, 0, 0, 0, 0 ]
NCT02409888
11:32:chronic_disease,53:66:chronic_disease,70:86:chronic_disease,126:150:chronic_disease
a serious psychiatric diagnosis (e.g., uncontrolled schizophrenia or major depression) as well as those meeting criteria for organic brain impairment, as measured by the mini-mental status examination section of the DIS-IV will be precluded from study participation
3
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NCT03121586
49:65:chronic_disease
Known family or personal history or symptoms of long QT syndrome
3
[ "Known", "family", "or", "personal", "history", "or", "symptoms", "of", "long", "QT", "syndrome" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 2, 2, 2 ]
NCT02040610
1:10:treatment
Bone scan is not required for patients enrolled with a single intermediate risk factor only, but this scan may be obtained at the discretion of the treating physician
3
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NCT01261728
,,,45:58:chronic_disease
Evidence of NYHA functional class III or IV heart disease
3
[ "Evidence", "of", "NYHA", "functional", "class", "III", "or", "IV", "heart", "disease" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 2, 2 ]
NCT01653093
7:29:chronic_disease
known circulatory impairment
3
[ "known", "circulatory", "impairment" ]
[ 0, 2, 2 ]
NCT03159936
,,101:112:treatment
Women of childbearing potential must use effective contraceptive methods in order to participate in tofacitinib clinical studies
3
[ "Women", "of", "childbearing", "potential", "must", "use", "effective", "contraceptive", "methods", "in", "order", "to", "participate", "in", "tofacitinib", "clinical", "studies" ]
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NCT02387216
,26:50:treatment
Not received more than 2 prior systemic therapies
3
[ "Not", "received", "more", "than", "2", "prior", "systemic", "therapies" ]
[ 0, 0, 0, 0, 0, 1, 1, 1 ]
NCT02446457
11:29:chronic_disease,48:66:treatment,,127:142:treatment,146:169:treatment
No active autoimmune disease that has required systemic treatment in past 2 years (i.e. with use of disease modifying agents, corticosteroids or immunosuppressive drugs)
3
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NCT02932410
1:58:chronic_disease
PAH associated with connective tissue diseases (PAH-aCTD)
3
[ "PAH", "associated", "with", "connective", "tissue", "diseases", "(", "PAH-aCTD", ")" ]
[ 2, 2, 2, 2, 2, 2, 2, 0, 0 ]
NCT02446886
34:51:chronic_disease
Patients with a known history of diabetes mellitus
3
[ "Patients", "with", "a", "known", "history", "of", "diabetes", "mellitus" ]
[ 0, 0, 0, 0, 0, 0, 2, 2 ]
NCT00924027
1:22:cancer
lymph node metastases
3
[ "lymph", "node", "metastases" ]
[ 3, 3, 3 ]
NCT02398773
32:55:treatment,60:78:cancer,94:122:treatment
Patient must NOT have received prior endocrine therapy for metastatic disease (i.e., must be first-line endocrine therapy for metastatic disease)
3
[ "Patient", "must", "NOT", "have", "received", "prior", "endocrine", "therapy", "for", "metastatic", "disease", "(", "i.e.", ",", "must", "be", "first-line", "endocrine", "therapy", "for", "metastatic", "disease", ")" ]
[ 0, 0, 0, 0, 0, 1, 1, 1, 0, 3, 3, 0, 0, 0, 0, 0, 1, 1, 1, 0, 0, 0, 0 ]
NCT02138617
46:60:cancer
Histological or cytological documentation of adenocarcinoma of the colon or rectum
3
[ "Histological", "or", "cytological", "documentation", "of", "adenocarcinoma", "of", "the", "colon", "or", "rectum" ]
[ 0, 0, 0, 0, 0, 3, 0, 0, 0, 0, 0 ]
NCT02565901
91:100:treatment,124:141:chronic_disease,164:174:treatment
patient must be offered and made aware of all Food and Drug Administration (FDA)‐approved treatment options; patients with bone only disease may not have received radium-223
3
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NCT02307058
4:17:treatment,25:37:treatment,,92:114:treatment,136:161:treatment
An anti-androgen (e.g., bicalutamide at 50 mg per day po) is recommended to start prior to LHRH agonist injection (not recommended for LHRH antagonist injection) and is recommended to not be administered
3
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NCT02769611
15:32:chronic_disease
Patients with acute myocarditis
3
[ "Patients", "with", "acute", "myocarditis" ]
[ 0, 0, 2, 2 ]
NCT02266329
15:36:chronic_disease
any period of loss of consciousness
3
[ "any", "period", "of", "loss", "of", "consciousness" ]
[ 0, 0, 0, 2, 2, 2 ]
NCT02584647
10:47:treatment
Agree to pre and post-treatment tumor biopsies
3
[ "Agree", "to", "pre", "and", "post-treatment", "tumor", "biopsies" ]
[ 0, 0, 1, 1, 1, 1, 1 ]
NCT02760498
,60:78:chronic_disease,93:102:treatment,108:134:treatment,135:145:treatment,174:203:chronic_disease
Ongoing or recent (within 5 years) evidence of significant autoimmune disease that required treatment with systemic immunosuppressive treatments, which may suggest risk for immune-related adverse events
3
[ "Ongoing", "or", "recent", "(", "within", "5", "years", ")", "evidence", "of", "significant", "autoimmune", "disease", "that", "required", "treatment", "with", "systemic", "immunosuppressive", "treatments", ",", "which", "may", "suggest", "risk", "for", "immune-related", "adverse", "events" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 2, 0, 0, 1, 0, 1, 1, 1, 0, 0, 0, 0, 0, 0, 2, 2, 2 ]
NCT02570256
34:49:chronic_disease
diffuse/multiple lesion sites or multiple stroke events
3
[ "diffuse/multiple", "lesion", "sites", "or", "multiple", "stroke", "events" ]
[ 2, 2, 0, 0, 0, 0, 0 ]
NCT00147056
104:113:chronic_disease
Symptoms and signs of increased intracranial pressure (e.g., headache, nausea, vomiting, lethargy, and papaedema)
3
[ "Symptoms", "and", "signs", "of", "increased", "intracranial", "pressure", "(", "e.g.", ",", "headache", ",", "nausea", ",", "vomiting", ",", "lethargy", ",", "and", "papaedema", ")" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 0 ]
NCT02323945
,,,57:70:chronic_disease
Age 18 and 75 years (the latter to reduce likelihood of heart disease)
3
[ "Age", "18", "and", "75", "years", "(", "the", "latter", "to", "reduce", "likelihood", "of", "heart", "disease", ")" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 2, 0 ]
NCT03007745
1:10:chronic_disease
cirrhosis
3
[ "cirrhosis" ]
[ 2 ]
NCT02584244
39:70:treatment
Subjects may have previously received pre-operative radiation therapy
3
[ "Subjects", "may", "have", "previously", "received", "pre-operative", "radiation", "therapy" ]
[ 0, 0, 0, 0, 0, 1, 1, 1 ]
NCT02585973
,159:175:treatment,
Not willing to avoid grapefruit, grapefruit juices, grapefruit hybrids, Seville oranges, pummelos, and exotic citrus fruits from 14 days prior to the dose of study medication, throughout the study, and until 2 weeks after the last dose of AZD1775 due to potential CYP3A4 interaction with the study medication
3
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NCT02962427
14:42:chronic_disease
Diagnosis of post-dural puncture headache based on the International Classification of Headache Disorders
3
[ "Diagnosis", "of", "post-dural", "puncture", "headache", "based", "on", "the", "International", "Classification", "of", "Headache", "Disorders" ]
[ 0, 0, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02496208
1:25:chronic_disease
Unstable angina pectoris
3
[ "Unstable", "angina", "pectoris" ]
[ 2, 2, 2 ]