Create README.md

README.md

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+### Description
+This dataset contains ΔΔG value of various protein mutations. The ΔΔG value indicates the stability of protein.
+
+### Splits
+traing: 486352
+
+valid: 60995
+
+test: 60492
+
+### Related paper 
+Tsuboyama, K., Dauparas, J., Chen, J. et al. Mega-scale experimental analysis of protein folding stability in biology and design. Nature 620, 434–444 (2023).
+https://doi.org/10.1038/s41586-023-06328-6.
+
+### Label
+Label means ΔΔG of each mutant amino acid sequence based on a deep mutation scanning experiment.
+
+#### Understanding ΔG (delta G)
+ΔG is the Gibbs free energy change of a process, dictating whether a process is thermodynamically favorable:
+
+Negative ΔG: Indicates the process is energetically favorable. For protein unfolding, it implies the protein is more stable in its unfolded form.
+
+Positive ΔG: Indicates the process is not energetically favorable. In protein unfolding, it means the protein requires energy to maintain its unfolded state, i.e. it is stable in folded form.
+
+#### The delta delta G (ΔΔG) represents the deltaG of the mutation compared to the base protein:
+
+Positive ΔΔG: Suggests the mutation enhances protein stability.
+
+Negative ΔΔG: Suggests the mutation decreases protein stability.