---
license: cc-by-nc-nd-4.0
tags:
- histopathology
- whole-slide-image
---

# BigCell sample data

This is a small sample of the data format used to train and evaluate
[BigCell](https://huggingface.co/StonyBrook-CVLab/BigCell) ([GitHub](https://github.com/cvlab-stonybrook/BigCell)).
It contains two 32,768×32,768 regions at 20×:

| Region | Source |
|---|---|
| `cptac/AML/C3L-00453-41_x0_y0` | CPTAC (AML) |
| `tcga_diagnostic/brca/TCGA-3C-AALI-01Z-00-DX1.F6E9A5DF-D8FB-45CF-B4BD-C6B76294C291_x0_y0` | TCGA-BRCA (diagnostic) |

Each region is cut into non-overlapping crops of 2048 to 32768 px, excluding background. The sample has
6.8 GB, 1,600 files.

## Layout

All crops are at 20×. `<size>` is the side length of the crop in pixels at 20×.

```
<source>/<type>/<slide>_x<X>_y<Y>/<size>/      size ∈ {2048, 4096, 8192, 16384, 32768}
    <N>.jpg          2048×2048 image (the crop downsampled when size > 2048)
    <N>_full.jpg     the crop at full resolution (size > 2048)
    <N>_uni.npy      (size/256, size/256, 1536) float16 UNI-2h grid, one token per 256×256 patch
    <N>_vae.npy      (64, 256, 256) float16 FLUX.2 VAE posterior mean ‖ std of <N>.jpg
metadata/
    image_list_train.h5      datasets size_<size>: relative paths of every <N>.jpg
    new_organ_split.csv      organ ↔ (source, type) used in the paper
image_embedding_stats/uni2_{4096,8192}/normalization_stats.pt
                             per-position mean / var of UNI-2 grids over the full training set (used by the CGM)
```

| size | crops | used for |
|---|---|---|
| 2048 | 367 | training the tile generator (`_vae.npy` + `_uni.npy`) |
| 4096 / 8192 | 93 / 24 | CGM training grids; 4k / 8k generation |
| 16384 / 32768 | 7 / 2 | 16k / 32k generation |

## Usage

```bash
huggingface-cli download StonyBrook-CVLab/BigCell-sample-data --repo-type dataset --local-dir bigcell_sample_data

# generate an 8192×8192 image from a real region's UNI-2 grid
python scripts/generate_from_grid.py --grid bigcell_sample_data/cptac/AML/C3L-00453-41_x0_y0/8192/0_uni.npy --out 8k.jpg

# fine-tune the 2048 tile generator on the sample
torchrun --nproc_per_node 4 -m bigcell.train configs/bigcell/2048.yaml --data-dir bigcell_sample_data \
    --init-from bigcell-2048 --batch-size 8 --max-train-steps 100
```

The TITAN report embeddings that the CGM is trained on are not part of this sample.

## License

CC BY-NC-ND 4.0. The images derive from CPTAC and TCGA, which are subject to their original data-use terms. The
UNI-2h features and FLUX.2 latents are subject to the licences of those models.